Method for producing gamma-aminobutyric acid with high yield through mixed fermentation

Through the mixed fermentation of Bifidobacterium lactis and Lactobacillus hilansergi, the problems of low GABA production and long cycle in the traditional single-bacteria fermentation method are solved, and the efficient production of γ-aminobutyric acid is achieved, which has important application value.

CN120665773AActive Publication Date: 2025-09-19SHANDONG NICE HEALTH TECHNOLOGY CO LTD
4 Cites 2 Cited by

Patent Information

Application Number
CN202510893081.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-30
Publication Date
2025-09-19
Estimated Expiration
2045-06-30

AI Technical Summary

Technical Problem

The traditional single-bacteria fermentation method for producing γ-aminobutyric acid (GABA) has problems such as low yield and long fermentation cycle, and is particularly affected by environmental factors, which limits the improvement of production efficiency and cost.

Method used

The mixed fermentation of Bifidobacterium lactis and Lactobacillus hilgeni promotes the growth of Lactobacillus hilgeni through the growth of Bifidobacterium lactis, and enhances the GABA production capacity by producing metabolites such as lactic acid and glutamate decarboxylase.

Benefits of technology

The GABA production was significantly improved. The mixed fermentation method can increase the GABA production by 2-3 times and shorten the fermentation cycle by more than 50%, which has significant technical advantages and economic benefits.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention belongs to the technical field of fermentation engineering and enzyme engineering, and particularly relates to a method for producing gamma-aminobutyric acid at high yield through mixed fermentation. Specifically, a mixed fermentation mode is adopted, the growth of lactobacillus hilgardii is promoted through the growth of bifidobacteria, and the synergistic interaction of the two strains is realized, so that the yield of GABA is greatly improved. Experimental results show that compared with traditional single-bacterium fermentation, the mixed fermentation method has the advantages that the yield of the GABA can be increased by 2-3 times, the fermentation period is shortened by 50% or above, and remarkable technical advantages and economic benefits are achieved. Therefore, the mixed fermentation method provided by the technical scheme provides an efficient and environment-friendly new way for the production of high-yield GABA, and has important application value and market prospect.
Need to check novelty before this filing date? Find Prior Art