Doxidine crystal form and preparation method and application thereof

By preparing the polydapoxetine crystal form, the stability problem of polydapoxetine pesticide during production, storage and transportation is solved, the preparation performance and efficacy are improved, and the stability and quality control of the crystal form are achieved.

CN120682123APending Publication Date: 2025-09-23SHANDONG WEIFANG RAINBOW CHEMICAL CO LTD
0 Cites 0 Cited by

Patent Information

Application Number
CN202510795563.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-13
Publication Date
2025-09-23

AI Technical Summary

Technical Problem

The different crystal forms of existing doxorubicin pesticides are easily transformed during production, storage and transportation, resulting in product crystallization, agglomeration, and reduced suspension rate, affecting efficacy. Traditional synthesis processes fail to effectively control crystal morphology, affecting formulation performance and stability.

Method used

A method for preparing a polymorphic polymorph is provided. By controlling the solvent and temperature conditions, block or flaky crystals are obtained. The crystal habit thereof is characterized by X-ray powder diffraction. A stable polymorph is prepared through a heating and stirring, cooling and crystallization, and drying process.

Benefits of technology

The stability of the polymorphic form of polyols and the performance of the preparation are improved, the uniformity of the product during production, storage and transportation is improved, the stability and efficacy of the preparation are ensured, and the quality standards of the original drug and the preparation are controlled.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention relates to the technical field of pesticide crystal form molecules, and discloses a dodine crystal form as well as a preparation method and application thereof. The dodine crystal form has characteristic absorption peaks when 2theta is 6.40 + / -0.2 degrees and 19.20 + / -0.2 degrees in an X-ray powder diffraction pattern of the dodine crystal form under Cu-K alpha radiation at the temperature of 25 DEG C; the crystal form has a block-shaped or sheet-shaped crystal habit. According to the invention, the crystal form singleness of the product in the production, storage and transportation processes can be ensured, and the stability of the product is ensured; and the crystal habit is qualitatively characterized by PXRD, so that the quality standard of the original medicine and the preparation can be more effectively controlled, and the standard is provided for the practical application process.
Need to check novelty before this filing date? Find Prior Art