Lactobacillus plantarum HNGD-YC1 capable of degrading free AGEs and application of lactobacillus plantarum HNGD-YC1

By screening out the acid-resistant and bile-resistant Lactobacillus plantarum HNGD-YC1 and fermenting it to prepare dairy products with low free AGEs, the problem of removing AGEs from food was solved, and efficient and safe food degradation effects were achieved.

CN120683015APending Publication Date: 2025-09-23HENAN UNIVERSITY OF TECHNOLOGY
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Patent Information

Application Number
CN202510920305.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-04
Publication Date
2025-09-23

AI Technical Summary

Technical Problem

Existing technologies are difficult to effectively remove high concentrations of free AGEs in food, and the safety and adaptability of traditional strains have not been fully verified, which limits their application in the food industry.

Method used

A strain of Lactobacillus plantarum HNGD-YC1 was screened out from dairy products. It has good acid and bile salt resistance and can degrade free AGEs in food through fermentation to prepare dairy products with low free AGEs.

Benefits of technology

Lactobacillus plantarum HNGD-YC1 can effectively degrade free AGEs with a degradation rate of up to 69.3%, and maintain a high survival rate in gastric juice and bile salt environments, providing a safe and effective food solution and reducing economic costs.

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Abstract

The invention belongs to the technical field of microorganisms, and particularly relates to lactobacillus plantarum HNGD-YC1 capable of degrading free-state advanced glycosylation end products (AGEs) and application of the lactobacillus plantarum HNGD-YC1. The strain is classified and named as Lactobacillus plantarum, and the preservation number of the strain is CCTCC M 20251498. The strain can effectively degrade free AGEs, and has good acid resistance and cholate resistance. Besides, lactic acid bacteria are adopted for degrading free AGEs in food for the first time, the degradation rate is 69.3%, and the lactobacillus has an excellent probiotic function, is high in strain activity, can easily pass through the stomach and be planted in the intestinal tract and is low in economic cost; the invention provides a novel safe and sustainable method for solving the problem that the food-sourced harmful factor AGEs enters the body to damage the health, and also provides a safer and more effective diet strategy for people with AGEs-related metabolic diseases, thereby being beneficial to promoting the healthy life of people.
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Citation Information

Patent Citations

  • Lactobacillus plantarum NKU SS120, culture and application

    CN118879581A