Efficient and rapid antibacterial composition as well as product and application thereof

Abstract

The invention provides an efficient and rapid antibacterial composition as well as a product and application thereof. The antibacterial composition provided by the invention contains cetyltrimethylammonium bromide (CTAB), didecyl dimethyl ammonium bromide, N-methyl di-n-octylamine and D-sphingosine, through scientific compounding, all the components play a synergistic effect, the antibacterial effect is remarkably improved, and the antibacterial composition has broad-spectrum antibacterial activity, can inhibit various bacteria and fungi, can quickly sterilize, and is free of toxic and side effects. Removing bacteria on the object surface. Through reasonable compounding of the proportion of all the components, the irritation of a composition system can be effectively reduced, the composition is mild to skin and free of irritation, the compounded D-sphingosine not only can enhance the antibacterial effect of the composition, but also can reduce the toxicity of CTAB, and the problem that the irritation of CTAB is large is solved; the prepared antibacterial gel product is good in sterilizing effect, better in stability, free of irritation to skin, simple and convenient in preparation method and wide in application range, and can be applied to various scenes such as personal care, medical disinfection and environment cleaning.

Description

Technical Field

[0001] The present invention belongs to the technical field of sterilization and disinfection compositions, and more specifically, relates to a high-efficiency and rapid antibacterial composition, its products, and applications. Background Art

[0002] Bacterial infections are a major cause of many diseases and health issues. Skin and environmental contamination by pathogens such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa is a widespread problem. Existing antimicrobial products often rely on single ingredients, resulting in limited effectiveness or prone to drug resistance. Due to overuse and the use of single mechanisms (such as cell wall destruction or protein synthesis inhibition) to kill bacteria, bacteria can easily develop drug resistance through genetic mutation or adaptive evolution. While some traditional antimicrobial agents, such as alcohol and benzalkonium chloride, have effective antibacterial properties, they are also highly irritating to the skin. Long-term use can damage the skin barrier, leading to dryness, redness, swelling, or allergies. Frequent use of antimicrobial products can also disrupt the beneficial bacterial flora on the skin's surface. These issues limit the long-term effectiveness and safety of antimicrobial products. Therefore, the development of novel antimicrobial agents is crucial to reducing the risk of bacterial resistance and irritation.

[0003] Due to their excellent surface activity and permeability, surfactants can disrupt microbial cell walls or membranes, achieving an antibacterial effect. Compared to traditional chemical disinfectants, some surfactants (particularly biosurfactants) have lower toxicity and better biocompatibility, making them relatively friendly to humans and the environment. However, surfactants prioritize their antibacterial effects and are often used in combination with other antimicrobial agents (such as antibiotics and silver ions) to enhance their effectiveness.

[0004] Although surfactants exhibit some antimicrobial activity, the types of surfactants currently used to prepare antimicrobial products are extremely limited. Some surfactants are irritating, toxic, and unstable. Because the antimicrobial mechanisms of most surfactants are still not fully understood, some highly effective surfactants may face production limitations and high costs, limiting their large-scale application. Therefore, it is necessary to develop more surfactant-based antimicrobial products with broad-spectrum antimicrobial activity, more efficient antimicrobial effects, resistance to drug resistance, minimal skin irritation, and good stability. Summary of the Invention

[0005] The present invention aims to solve the technical problems of limited effect, easy drug resistance and severe skin irritation of existing antibacterial products, and provide a high-efficiency and fast-acting antibacterial composition, product and application thereof.

[0006] The object of the present invention is to provide an antibacterial composition.

[0007] Another object of the present invention is to provide an application of the antibacterial composition.

[0008] Yet another object of the present invention is to provide a product.

[0009] The above-mentioned purpose of the present invention is achieved through the following technical solutions: The invention provides an antibacterial composition, which comprises raw materials in the following mass ratio: hexadecyltrimethylammonium bromide: didecyldimethylammonium bromide: N-methyldi-n-octylamine: D-sphingosine = (0.5-2): (0.1-5): (0.1-5): (0.01-1).

[0010] The present invention combines cetyltrimethylammonium bromide (CTAB), didecyldimethylammonium bromide, N-methyldioctylamine, and D-sphingosine. Through this scientifically formulated combination, the components synergistically enhance each other, significantly improving antibacterial efficacy. The product exhibits broad-spectrum antibacterial activity against a wide range of bacteria and fungi, including significant antibacterial activity against common pathogens such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. It rapidly kills bacteria and removes bacteria from surfaces. Furthermore, the synergistic effect of the active ingredients reduces the irritation of the composition, resulting in a mild and non-irritating effect on the skin. The addition of D-sphingosine not only enhances the antibacterial efficacy of the composition but also reduces the toxicity of CTAB, providing a certain degree of repair and reparative properties, thereby addressing the significant irritation associated with CTAB. The resulting antibacterial gel product exhibits excellent bactericidal efficacy, superior stability, and is non-irritating to the skin. Its preparation method is simple and has a wide range of applications, including personal care, medical disinfection, and environmental cleaning.

[0011] Preferably, the antibacterial composition comprises raw materials in the following mass ratio: hexadecyltrimethylammonium bromide: didecyldimethylammonium bromide: N-methyldioctylamine: D-sphingosine = 1: (0.1-5): (0.1-5): (0.01-1).

[0012] The present invention provides application of the composition in disinfection and sterilization in personal care, medical disinfection and environmental cleaning.

[0013] The present invention provides the use of the above composition in the preparation of antibacterial products.

[0014] The present invention also provides use of the above composition in inhibiting bacteria and fungi for purposes other than disease diagnosis and treatment.

[0015] Preferably, the bacteria inhibited by the composition or antibacterial product are one or more of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Pseudomonas aeruginosa, Candida albicans, and Propionibacterium acnes; the fungi inhibited by the composition or antibacterial product are one or more of Candida albicans and Malassezia.

[0016] The present invention provides a product containing the above composition.

[0017] Preferably, the product comprises the following raw materials in weight percentage: 0.1%-0.5% hexadecyltrimethylammonium bromide, 0.05%-0.5% didecyldimethylammonium bromide, 0.1%-0.5% N-methyldioctylamine, 0.01%-0.1% D-sphingosine, and the balance is deionized water.

[0018] In particular, the product can be formulated into a transparent gel, antibacterial spray, or emulsion, allowing for flexible adjustments based on usage requirements. The resulting antibacterial gel offers excellent bactericidal efficacy, excellent stability, and is non-irritating to the skin. Its simple preparation method offers a wide range of applications, including personal care, medical disinfection, and environmental cleaning.

[0019] More preferably, the product is an antibacterial gel.

[0020] Preferably, the product further contains a gel base and a moisturizer.

[0021] Preferably, the product further comprises the following raw materials in weight percentage: gel matrix 1%-5%, moisturizer 1%-10%.

[0022] More preferably, the gel matrix is ​​selected from hydroxyethyl cellulose, sodium alginate or a mixture thereof; and the moisturizing agent is selected from glycerin, propylene glycol, sodium hyaluronate or a mixture thereof.

[0023] The compositions provided by this invention can be used in a variety of scenarios, including personal care (such as antibacterial sprays and hand sanitizers), medical disinfection (such as wound cleansing solutions), and environmental cleaning. In the medical and health sector, they can be used as surgical disinfectants and medical antibacterial cleansers; in daily care, they can be used in antibacterial sprays, hand sanitizers, and skin care products; and in public disinfection, they can be used for surface cleaning and air disinfection, improving public health safety.

[0024] The present invention provides application of the above product in disinfection and sterilization for personal care, medical disinfection and environmental cleaning.

[0025] The present invention has the following beneficial effects: The present invention provides a highly effective and rapid antibacterial composition having the following advantages: (1) Synergistic effect enhances antibacterial properties: The antibacterial composition contains CTAB, didecyldimethylammonium bromide, N-methyldioctylamine and D-sphingosine. There is a significant synergistic effect between the components, and it has broad-spectrum antibacterial properties. Its antibacterial effect is better than that of a single component or a simple mixture, and it has significant antibacterial activity.

[0026] (2) Gentle and safe: While improving the antibacterial effect of the composition, it can also significantly reduce the irritation to the skin, solving the problem of high irritation of CTAB. It is gentle and non-irritating to the skin and suitable for long-term use.

[0027] (3) Wide range of applications: The antibacterial composition provided by the present invention can be used in various scenarios such as personal care (such as antibacterial spray, hand sanitizer), medical disinfection (such as wound cleaning solution) and environmental cleaning.

[0028] (4) High stability: The antibacterial composition provided by the present invention exhibits good stability under long-term storage and different temperature conditions, is not prone to stratification or failure, and extends the shelf life of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 This is the result of the inhibition zone experiment on five strains in Example 2.

[0030] Figure 2 Graph showing the results of the inhibition zone experiment on five strains in Example 3.

[0031] Figure 3 The results of the inhibition zone test of Example 2 and the positive control against Candida albicans and Malassezia are shown (in the figure, Example is the composition of Example 2, Comparative Example is the positive control group, and CON is the blank control). DETAILED DESCRIPTION

[0032] The present invention will be further described below with reference to the accompanying drawings and specific examples, but the examples do not limit the present invention in any way. Unless otherwise specified, the reagents, methods and equipment used in the present invention are conventional reagents, methods and equipment in the art.

[0033] Unless otherwise specified, the reagents and materials used in the following examples were commercially available.

[0034] Example 1 Selection of antibacterial components 1. Selection of antibacterial ingredients The antibacterial ingredients are selected from the following raw materials: cetyltrimethylammonium bromide (CTAB), didecyldimethyl bromide, N-methyldioctylamine, and D-sphingosine.

[0035] 2. Preparation of different ingredient concentrations Dissolve the above ingredients in deionized water and prepare different concentrations for later use. The specific concentrations and combinations are as follows: (1) Antibacterial ingredients used alone: ​​CTAB (0.5%), didecyldimethylammonium bromide (0.5%), N-methyldioctylamine (0.5%), and D-sphingosine (0.1%).

[0036] (2) Antibacterial ingredients in pairs (mixed in a 1:1 mass ratio, with a concentration of 1% of the total amount): CTAB + didecyldimethylammonium bromide, CTAB + N-methyldioctylamine, CTAB + D-sphingosine, didecyldimethylammonium bromide + N-methyldioctylamine, didecyldimethylammonium bromide + D-sphingosine, N-methyldioctylamine + D-sphingosine.

[0037] (3) Combination of three ingredients (mixed in a mass ratio of 1:1:1, and the total concentration was adjusted to 1%): CTAB + didecyldimethylammonium bromide + N-methyldioctylamine, CTAB + didecyldimethylammonium bromide + D-sphingosine, CTAB + N-methyldioctylamine + D-sphingosine, didecyldimethylammonium bromide + N-methyldioctylamine + D-sphingosine.

[0038] (4) A combination of four ingredients (mixed in a mass ratio of 1:1:1:1, with the total concentration adjusted to 1%): CTAB + didecyl dimethyl bromide + N-methyl dioctylamine + D-sphingosine.

[0039] 3. Antibacterial effect Bacterial strain selection: Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were selected as pathogens, and the strains were sourced from standard laboratory strains.

[0040] The agar diffusion method was used to test the bacteria. 1×10 8 The CFU / mL bacterial suspension was evenly spread on the surface of the agar medium. A hole was made on the agar surface, and the sample solutions of different concentrations were injected into the hole. For the combined sample, the components were mixed according to the above ratio and injected into the hole. The agar medium was placed in an incubator at 37°C for 24 hours.

[0041] 4. Inhibition zone measurement The antibacterial effects of different samples against the three pathogens were recorded by observing and measuring the diameter of the inhibition zone around each well. The statistical results of the inhibition zones at different concentrations and combinations are shown in Table 1 below. This indicates that each component exhibits a certain antibacterial effect when used alone, but the antibacterial effect gradually increases after compounding. At the same concentration, the combination of CTAB, didecyldimethylammonium bromide, N-methyldioctylamine, and D-sphingosine exhibits the most significant antibacterial effect. Lowering the concentration and dosage of each component actually enhances the antibacterial effect. The components exhibit significant synergistic effects, effectively inhibiting the growth of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, demonstrating the strongest antibacterial activity.

[0042] Table 1 Antibacterial properties of different concentrations and combinations

[0043] Example 2 Antibacterial composition The formula is: 0.5 g of hexadecyltrimethylammonium bromide (CTAB), 0.5 g of didecyldimethylammonium bromide, 0.5 g of N-methyldioctylamine, 0.1 g of D-sphingosine, and deionized water to make up to 100 g.

[0044] Preparation method: Dissolve CTAB, didecyldimethylammonium bromide and N-methyldioctylamine in 30 g of deionized water and stir until completely dissolved; adjust the pH to 5.5 with dilute NaOH solution, filter and divide into packages.

[0045] Example 3 Preparation of antibacterial gel The antibacterial composition is used to prepare antibacterial products, which can be used in various scenarios such as personal care (such as antibacterial spray, hand sanitizer), medical disinfection (such as wound cleaning solution) and environmental cleaning. It can be used to make transparent gel, antibacterial spray or emulsion form, and can be flexibly adjusted according to usage requirements.

[0046] The composition of Example 2 was prepared into an antibacterial gel product, and a gel matrix and a moisturizer were further added to the composition. The gel matrix was selected from hydroxyethyl cellulose, sodium alginate, or a mixture thereof; and the moisturizer was selected from glycerin, propylene glycol, sodium hyaluronate, or a mixture thereof.

[0047] The formula of the antibacterial gel is: CTAB 0.5 g, didecyldimethylammonium bromide 0.5 g, N-methyldioctylamine 0.5 g, D-sphingosine 0.1 g, glycerol 5.0 g, hydroxyethyl cellulose 0.5 g, and deionized water to make up to 100 g.

[0048] Preparation method of antibacterial gel: weigh 30 g of deionized water and place it in a stirring container, add CTAB and didecyldimethylammonium bromide in sequence, stir until completely dissolved, then add hydroxyethyl cellulose to swell to form a gel matrix, add glycerol and D-sphingosine in sequence, cool to room temperature, add deionized water to 100 g, and then package to prepare the antibacterial gel.

[0049] Comparative Example 1 Composition without D-sphingosine The formula of the antibacterial composition is: 0.5 g of hexadecyltrimethylammonium bromide (CTAB), 0.5 g of didecyldimethylammonium bromide, 0.5 g of N-methyldioctylamine, and deionized water to make up to 100 g.

[0050] Preparation method: Dissolve CTAB, didecyldimethylammonium bromide and N-methyldioctylamine in 30 g of deionized water and stir until completely dissolved; adjust the pH to 5.5 with dilute NaOH solution; add deionized water to 100 g, filter and divide into packages.

[0051] Comparative Example 2 The formula of other surfactant antibacterial compositions is: dodecyltrimethylammonium chloride (DTAC) 1.0g, octylphenoxyethanol (OPE) 1.0g, cetyltrimethylammonium bromide (CTAB) 1.0g, benzalkonium chloride 1.0g, and deionized water to make up to 100g.

[0052] Comparative Example 3 The preparation of the antibacterial composition was the same as in Example 2, except that 0.3 g of cetyltrimethylammonium bromide (CTAB), 1.2 g of didecyldimethylammonium bromide, 0.8 g of N-methyldioctylamine, 0.6 g of D-sphingosine, and deionized water were used to make up to 100 g.

[0053] Comparative Example 4 The preparation of the antibacterial composition was the same as in Example 2, except that 0.4 g of cetyltrimethylammonium bromide (CTAB), 1 g of didecyldimethylammonium bromide, 0.6 g of N-methyldioctylamine, 0.7 g of D-sphingosine, and deionized water were used to make up to 100 g.

[0054] Comparative Example 5 The preparation of the antibacterial composition was the same as in Example 2, except that 1.2 g of cetyltrimethylammonium bromide (CTAB), 0.8 g of didecyldimethylammonium bromide, 0.5 g of N-methyldioctylamine, 0.6 g of D-sphingosine, and deionized water were used to make up to 100 g.

[0055] In Comparative Examples 3-5, by adjusting the ratio of the components of the antibacterial composition, it was determined that each group also had certain antibacterial properties, but the effect was lower than that of the composition in Example 2. Overall, it did not show a better synergistic effect, and there was also a certain skin irritation.

[0056] Test Example 1 Sterilization Speed ​​Test The short-term bactericidal efficacy of different antimicrobial compositions was tested. All bacterial species were provided by the Guangdong Institute of Microbiology. Suspensions of Staphylococcus aureus (ATCC 6538) and Escherichia coli (ATCC 25922) were mixed with the test sample at a ratio of 1:9 (final concentration 1%). Samples were collected at 1, 5, 10, and 30 minutes, and colony counts were performed. A commercially available hand sanitizer gel was also tested as a control. The bactericidal efficacy of each composition was calculated using the following formula.

[0057]

[0058] The results are shown in Table 2 below, which shows that the bactericidal composition and product of Example 2 can achieve a bactericidal effect of more than 95% in about 10 minutes, and the bactericidal rate increases rapidly in a period of time, and the effect is significantly better than the comparative example and the control product; although the bactericidal composition of Comparative Example 1 also has a good effect at 10 minutes, it is more irritating.

[0059] Table 2 Sterilization rate of different samples

[0060] Test Example 2 Skin irritation test The skin irritation of different samples was compared. Thirty volunteers were selected and divided into two groups based on gender. Within each group, there were five volunteers, each divided into a youth group (18 to 35 years old), a middle-aged group (36 to 59 years old), and an elderly group (over 60 years old). Each group applied the samples of Example 2, Example 3, Comparative Example 1, Comparative Example 2, and Comparative Example 3 to different areas on the inner forearm. Reactions such as redness, swelling, and itching were observed within 48 hours, and an irritation score (0-5) was recorded. The irritation score was set according to international standards such as the European Pharmacopoeia or ISO 10993-10 (Biological Evaluation of Skin Irritation Test Standard). 0 is no irritation (no redness, swelling, itching, or skin damage); 1 is mild irritation (mild redness, swelling, intact skin, and no exudation); 2 is moderate irritation (obvious redness, swelling, and slight skin damage or cracking); 3 is severe irritation (obvious redness, swelling, and mild blistering or peeling); 4 is very severe irritation (obvious redness, swelling, and numerous blisters or skin ulcerations); and 5 is extreme irritation (extensive ulceration, skin peeling, severe redness, swelling, or bleeding). The incidence of redness and swelling is the percentage of participants who experienced redness and swelling.

[0061] The results, as shown in Table 3 below, show that the antibacterial composition of Comparative Example 1 was the most irritating, resulting in a high incidence of skin redness and swelling, while Examples 2 and 3 were the least irritating to the skin. Comparing Example 2 with Comparative Example 1 demonstrates that adding D-sphingosine to the antibacterial composition not only enhances the antibacterial effect but also reduces the composition's irritation, demonstrating a certain restorative effect. By rationally adjusting the concentrations and dosages of the various components, the toxicity of CTAB is reduced, resulting in a mild, non-irritating skin composition while exhibiting significant antibacterial efficacy. Further preparation into a gel product, the addition of a gel base and a moisturizer further reduces irritation, enhancing safety.

[0062] Table 3 Skin irritation of different samples

[0063] Test Example 3 Surface Sterilization Effect The bactericidal efficacy of different antimicrobial compositions on surfaces was tested. A suspension of Staphylococcus aureus was inoculated on a stainless steel surface and allowed to dry naturally. After determining the initial colony count, the surface was wiped with samples from Examples 2 and 3 and Comparative Examples 1-3. After 5 minutes, samples were taken to measure the colony count.

[0064] The results are shown in Table 4 below, which shows that the test results of the sterilization effect on the stainless steel surface in the environment show that the sterilization effects of the sterilization compositions and products of Examples 2 and 3 are the best, and their effects are significantly better than those of Comparative Examples 1-3, and they can effectively kill bacteria on the surface of objects.

[0065] Table 4 Surface sterilization effect of different samples

[0066] Test Example 4 Broad-spectrum antibacterial activity 1. Antibacterial effect on different bacteria The antibacterial compositions and products of Examples 2 and 3 were used to perform inhibition zone tests and minimum inhibitory concentration tests on Gram-negative bacteria: Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 15442); Gram-positive bacteria: Staphylococcus aureus (ATCC 6538), Candida albicans (ATCC 10231), and Propionibacterium acnes (ATCC 11827). The bacterial solution concentration in the inhibition zone test was 1×10 8 CFU / mL (standard laboratory strain).

[0067] The antibacterial results of the antibacterial composition of Example 2 are shown in Table 5 below, which shows that the antibacterial composition of Example 2 has a good inhibitory effect on five different bacteria. Figure 1 As shown, its minimum inhibitory concentration is as low as 0.02~0.09ml / ml.

[0068] Table 5 Evaluation of the antibacterial effect of Example 2 on five strains

[0069] The antibacterial results of the antibacterial gel product of Example 3 are shown in Table 6 below, which shows that the antibacterial product of Example 3 has a good inhibitory effect on five types of bacteria. Figure 2 As shown, because the gel contains ingredients such as a gel matrix and a moisturizer, its antibacterial effect is slightly weaker than that of the antibacterial composition of Example 2, and its minimum inhibitory concentration is between 0.02 and 0.16 ml / ml.

[0070] Table 6 Evaluation of the antibacterial effect of Example 3 on five strains

[0071] 2. Antibacterial effect on fungi The antibacterial effects of the positive control sample (a commercially available hand-free antibacterial gel product) and Example 2 on the fungi Candida albicans (ATCC 10231) and Malassezia (ATCC 44344) were compared, and the inhibition zone test was performed to compare the antibacterial performance.

[0072] The results are shown in Table 7 below, which show that the antibacterial composition of Example 2 also has a good antibacterial effect on fungi. Figure 3 As shown, it can inhibit Candida albicans and Malassezia. Compared with existing antibacterial products, the antibacterial composition provided by the present invention is a mild formula and has the characteristics of broad-spectrum antibacterial activity, synergistic enhancement and low irritation.

[0073] Table 7 Statistics of inhibition zone diameters of Example 2 and the positive control against Malassezia and Candida albicans

[0074] In summary, the present invention provides a highly effective and rapid antibacterial composition comprising cetyltrimethylammonium bromide (CTAB), didecyldimethylammonium bromide, N-methyldioctylamine, and D-sphingosine. Through the scientifically formulated synergistic effect between the components, the composition significantly enhances antibacterial performance and exhibits broad-spectrum antibacterial activity, inhibiting a wide range of bacteria and fungi, while rapidly sterilizing and removing bacteria from surfaces. By rationally blending the components in appropriate proportions, the composition reduces the toxicity of CTAB, resulting in a mild and non-irritating effect on the skin. The addition of D-sphingosine not only enhances the antibacterial efficacy of the composition but also reduces its irritation, addressing the significant irritation associated with CTAB and providing a certain degree of repair. The composition can be prepared into an antibacterial product and further added with a gel base, a moisturizer, and other ingredients to produce an antibacterial gel product with excellent bactericidal efficacy, superior stability, and no skin irritation. The composition is simple to prepare and has a wide range of applications, including personal care, medical disinfection, and environmental cleaning.

[0075] The above embodiments are preferred implementation modes of the present invention, but the implementation modes of the present invention are not limited to the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications that do not deviate from the spirit and principles of the present invention should be considered as equivalent replacement methods and are included in the scope of protection of the present invention.

Claims

1. An antibacterial composition, characterized in that The method comprises raw materials in the following mass ratio: hexadecyltrimethylammonium bromide: didecyldimethylammonium bromide: N-methyldioctylamine: D-sphingosine = (0.5-2): (0.1-5): (0.1-5): (0.01-1).

2. The composition according to claim 1, characterized in that The method comprises raw materials in the following mass ratio: hexadecyltrimethylammonium bromide: didecyldimethylammonium bromide: N-methyldioctylamine: D-sphingosine = 1: (0.1-5): (0.1-5): (0.01-1).

3. Use of the composition according to claim 1 or 2 in disinfection and sterilization in personal care, medical equipment, and environmental cleaning.

4. Use of the composition according to claim 1 or 2 in the preparation of antibacterial products.

5. A product, characterized in that Containing the composition according to claim 1 or 2.

6. The product according to claim 5, characterized in that: The product comprises the following raw materials in percentage by weight: 0.1%-0.5% hexadecyltrimethylammonium bromide, 0.05%-0.5% didecyldimethylammonium bromide, 0.1%-0.5% N-methyldioctylamine, 0.01%-0.1% D-sphingosine, and the balance is deionized water.

7. The product according to claim 6, characterized in that The product also contains a gel matrix and a moisturizer.

8. The product according to claim 7, characterized in that: The product further comprises the following raw materials in weight percentage: 1%-5% gel matrix and 1%-10% moisturizer.

9. The product according to claim 8, characterized in that The gel matrix is ​​selected from hydroxyethyl cellulose, sodium alginate or a mixture thereof; the moisturizing agent is selected from glycerin, propylene glycol, sodium hyaluronate or a mixture thereof.

10. Use of the product according to any one of claims 6 to 9 in disinfection and sterilization in personal care, medical disinfection, and environmental cleaning.

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