Composition for turning white hair into black hair as well as preparation method, product and application of composition

Abstract

The invention belongs to the field of cosmetics, and particularly relates to a composition for turning white hair into black hair as well as a preparation method, a product and application of the composition. The composition comprises the following effective components: a red formononetin root extract, a black oat seed extract, an emblic leafflower fruit extract and glycoprotein, the composition further comprises water, an ammonium acryloyldimethyl taurate / VP copolymer, butanediol, glycerin, trehalose, betaine, allantoin, phenoxyethanol and ethylhexylglycerin. The composition can directly stimulate the activity of melanin cells, promote synthesis and transportation of melanin and fundamentally promote blackening of white hair. The composition provided by the invention can directly solve the core mechanism of the white hair problem, and is expected to bring revolutionary breakthrough to treatment or prevention of white hair.

Description

Technical Field

[0001] The present invention belongs to the field of cosmetics, and in particular relates to a composition for converting white hair into black hair, a preparation method thereof, a product and an application thereof. Background Art

[0002] As people's living standards improve, their pursuit of external appearance is also getting higher and higher. Hair color is one of the important factors affecting external appearance. The appearance of gray hair can give people a sense of aging, so many people hope to turn gray hair black and restore their youthful and beautiful image.

[0003] Existing "white hair blackening" products fall into four categories: a. Shampoo and conditioner products, primarily shampoo, such as "One Wash Black," primarily cleanse. While these products claim to turn white hair black, they actually use dyes to color hair. b. Herbal hair products claiming to be naturally derived from herbs, free of side effects, and capable of "blackening" hair have emerged on major e-commerce platforms and are even selling like hotcakes in brick-and-mortar stores. They claim to stimulate hair follicles to produce "natural melanin," naturally darkening hair. However, testing has revealed that the actual active ingredients in some products that cause hair darkening are chemicals like silver nitrate. These products, through exposure to light or heat lamps, induce oxidation on the surface of gray hair, visually changing its color. Using these products can pose a health risk. c. Oral supplements, primarily health products, such as the "Black Five" supplements, typically black sesame seeds, black beans, black rice, black wolfberries, and mulberries, primarily contain protein, vitamins, and minerals, primarily for nutritional purposes. Scientific evidence suggests they do not actually "blacken" hair. d. Physical therapy: In addition to products, there are also various services for turning gray hair into black on the market, such as head massage, muscle massage, scraping, fumigation, etc. These services focus on comfort and relaxation, and have the effect of promoting blood circulation, but there is no scientific basis for turning gray hair into black.

[0004] Hair color is primarily determined by melanin synthesized by melanocytes within the hair follicles. Melanin granules are transported to the hair shaft, giving the hair its color. When the melanin content in the hair follicles and hair decreases, the hair gradually turns gray. Conversely, if the melanin content in the hair follicles and hair increases, gray hair can turn black. The melanin content in the hair follicles is a key factor influencing hair color. Melanocytes within the hair follicles are responsible for producing melanin granules, and the amount of these granules directly determines hair color. When the melanin content in the hair follicles decreases, the hair turns gray. To turn gray hair black, the melanocytes in the hair follicles need to be activated to increase melanin production.

[0005] Furthermore, while basal melanocytes primarily influence skin color, they are linked to hair follicle melanocytes. The health of basal melanocytes may indirectly influence the activity of hair follicle melanocytes. Therefore, maintaining healthy skin may also help promote the activity of hair follicle melanocytes, thereby helping to darken gray hair.

[0006] Therefore, there is an urgent need to develop a composition that directly targets melanocyte dysfunction to provide a more effective treatment plan for turning gray hair black. Summary of the Invention

[0007] In view of the above-mentioned deficiencies, the present invention provides a composition that can directly act on melanocytes in hair follicles, promote their activity enhancement and melanin synthesis, and thus gradually turn white hair black.

[0008] The technical solution of the present invention is: In one aspect, the present invention provides a composition for converting white hair into black hair, comprising a red onion root extract, a black oat seed extract, a phyllanthus emblica fruit extract, and glycoprotein.

[0009] Specifically, the composition further comprises one or more of a thickener, a moisturizer or a preservative.

[0010] More specifically, the thickener includes, but is not limited to, one or more of ammonium acryloyldimethyltaurate / VP copolymer, xanthan gum, carrageenan, guar gum, gum arabic, hydroxyethyl cellulose, hydroxypropyl methylcellulose, carbomer, sodium polyacrylate, polyvinyl alcohol, or polyethylene glycol.

[0011] Preferably, the thickener may be ammonium acryloyldimethyltaurate / VP copolymer.

[0012] More specifically, the moisturizing agent includes but is not limited to one or more of butylene glycol, glycerin, 1,3-propylene glycol, propylene glycol, sodium hyaluronate, trehalose, betaine, sorbitol, mannitol or sodium pyrrolidonecarboxylate.

[0013] Preferably, the moisturizing agent may be butylene glycol, glycerin, 1,3-propylene glycol, trehalose and betaine.

[0014] More specifically, the preservative includes but is not limited to one or more of phenoxyethanol, ethylhexylglycerin, caprylyl glycol, pentylene glycol or 1,2-hexanediol.

[0015] Preferably, the preservatives may be phenoxyethanol and ethylhexylglycerin.

[0016] Specifically, the composition consists of Ononopus rubra root extract, Oat black seed extract, Emblica officinalis fruit extract, allantoin, bisabolol, glycoprotein, ammonium acryloyldimethyltaurate / VP copolymer, butylene glycol, glycerin, 1,3-propylene glycol, trehalose, betaine, phenoxyethanol and ethylhexylglycerin.

[0017] Preferably, the composition comprises, by weight percentage, 0.013-0.015% of red onion root extract, 0.013-0.015% of black oat seed extract, 0.030-0.035% of emblica fruit extract, 0.000006-0.000008% glycoprotein, 0.1-0.2% allantoin, 0.4-0.6% ammonium acryloyldimethyltaurate / VP copolymer, 2-3% butylene glycol, 1.0-1.2% glycerin, 1-1.5% trehalose, 0.5-1% betaine, 0.45-0.48% phenoxyethanol and 0.05-0.08% ethylhexylglycerin, with the balance being water.

[0018] Preferably, in some embodiments, the composition is composed, by weight percentage, of 0.013% of red onion root extract, 0.013% of black oat seed extract, 0.030% of emblica fruit extract, 0.000006% glycoprotein, 0.1% allantoin, 0.6% ammonium acryloyldimethyltaurate / VP copolymer, 2% butylene glycol, 1.0% glycerin, 1% trehalose, 0.5% betaine, 0.45% phenoxyethanol and 0.05% ethylhexylglycerin, with the balance being water.

[0019] Preferably, in other embodiments, the composition is composed, by weight percentage, of 0.015% of Ononopus rubra root extract, 0.015% of Black Oat Seed Extract, 0.035% of Emblica officinalis fruit extract, 0.000008% of glycoprotein, 0.2% of allantoin, 0.4% of ammonium acryloyldimethyltaurate / VP copolymer, 3% of butylene glycol, 1.2% of glycerin, 1.5% of trehalose, 1% of betaine, 0.48% of phenoxyethanol and 0.08% of ethylhexylglycerin, and the balance is water.

[0020] In another aspect, the present invention provides a method for preparing the aforementioned composition, comprising the following steps: S1. Accurately weigh water and ammonium acryloyldimethyltaurate / VP copolymer and add them to the main beaker. Stir evenly after swelling to obtain A. S2. Accurately weigh and sequentially add glycerol, butylene glycol, betaine, trehalose, and allantoin to solution A until completely dissolved to obtain solution B. S3. Add the red onion root extract, black oat seed extract, Kerascalp emblica fruit extract, Wisegrade glycoprotein, phenoxyethanol and ethylhexylglycerin to B in sequence and mix well.

[0021] In another aspect, the present invention provides use of the aforementioned composition or preparation method in preparing a product for promoting black hair / preventing gray hair.

[0022] Specifically, the product includes a head care product or a medicine.

[0023] Preferably, the head care products include but are not limited to: scalp essence, scalp scrub, scalp massage oil, scalp spray, conditioner, hair mask, hair care essential oil, hair care spray, shampoo, shampoo soap, dry shampoo spray, hair gel, hair wax, hair mud or styling spray.

[0024] In yet another aspect, the present invention provides a head care product, comprising the aforementioned composition.

[0025] In particular, the composition is the sole or main active ingredient of a head care product.

[0026] Specifically, the head care product further comprises other ingredients for improving product texture, stability, sensory experience or auxiliary efficacy.

[0027] Specifically, the head care products include but are not limited to: scalp essence, scalp scrub, scalp massage oil, scalp spray, conditioner, hair mask, hair care essential oil, hair care spray, shampoo, shampoo soap, dry shampoo spray, hair gel, hair wax, hair mud or styling spray.

[0028] In yet another aspect, the present invention provides a medicine comprising the aforementioned composition.

[0029] Specifically, the drug further includes pharmaceutically acceptable excipients.

[0030] Preferably, the pharmaceutically acceptable excipient is selected from one or a combination of two or more of wetting agents, emulsifiers, preservatives, antioxidants, buffers, excipients, diluents, lubricants, antibacterial agents, suspending agents, suspending aids, solubilizers, thickeners, stabilizers, sweeteners and flavors.

[0031] Preferably, the pharmaceutically acceptable excipient is selected from at least one of lactose, mannose, starch, gum arabic, calcium phosphate, alginate, gelatin, calcium silicate, polyvinyl pyrrolidone, cellulose, water, syrup, methylcellulose, methyl hydroxybenzoate, propyl hydroxybenzoate, magnesium stearate and mineral oil.

[0032] Specifically, the dosage form of the drug includes, but is not limited to, tablets, liquids, capsules, powders, suppositories, granules, sprays, liniments, ointments, creams, gels, lotions, sprays or patches.

[0033] Specifically, the drug is administered orally, intravenously, topically, intradermally or subcutaneously.

[0034] Preferably, the drug can be administered topically.

[0035] Specifically, the drug can also be used in combination with other drugs that promote black hair / prevent gray hair.

[0036] The beneficial effects of the present invention are: (1) The composition provided by the present invention can effectively reduce the degree of whitening of hair and hair follicles in mice with hydroquinone-induced leukoderma.

[0037] (2) The composition provided by the invention can significantly increase the melanin content in the hair of mice with hydroquinone-induced leukoderma.

[0038] (3) The composition provided by the invention can effectively increase the number and activity of basal melanocytes in the skin of mice with hydroquinone-induced leukoplakia. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 Figure 2 is the albino status of the test area of ​​each group of mice.

[0040] Figure 2 Microscopic observation of the hair in the test area of ​​each group of mice (magnification 200).

[0041] Figure 3 Microscopic observation of hair follicles in the test area of ​​mice in each group (magnification 200).

[0042] Figure 4 Statistical analysis of the relative content of hair melanin in the test area of ​​each group of mice. *p<0.05 indicates that the difference is statistically significant compared with the corresponding group.

[0043] Figure 5 The hair follicle images of the skin of the test area of ​​mice in each group were stained with ferrous sulfate method (magnification 200).

[0044] Figure 6 The basal images of the skin of the test area of ​​mice in each group were stained with ferrous sulfate method (magnification 200). DETAILED DESCRIPTION

[0045] The present invention will be further clarified and fully described below by way of examples. The following examples are only a portion of the present invention and are not intended to limit the present invention, but are merely for illustration. The experimental methods used in the following examples are all routine experiments unless otherwise specified, and the materials and reagents used in the following examples are all commercially available unless otherwise specified.

[0046] The main instruments and reagents used in this invention are shown in Table 1: Table 1

[0047] Example 1 (1) The formulation of the composition provided in this embodiment See Table 2: Table 2

[0048] (2) Preparation method of the composition S1. Accurately weigh water and ammonium acryloyldimethyltaurate / VP copolymer and add them to the main beaker. Stir evenly after swelling to obtain A. S2. Accurately weigh and add glycerol, butylene glycol, betaine, trehalose, and allantoin to the main beaker in sequence; S3. Start stirring in the main beaker and heat to about 80°C until the solution is completely dissolved; S4. Slowly cool to 45°C, weigh and add Formononetum root extract, black oat seed extract, Kerascalp emblica fruit extract, Wisegrade glycoprotein, phenoxyethanol, and ethylhexylglycerin in sequence, and stir until uniformly dispersed; S5. Cool down to below 40℃ and end.

[0049] Example 2 The formula of the composition provided in this embodiment is shown in Table 3: Table 3

[0050] The preparation method of the composition is the same as that of Example 1.

[0051] Effect Examples Hydroquinone has a strong competitive inhibitory effect on tyrosinase, which can reduce the formation of melanosomes and change the internal structure of melanosomes. In this example, hydroquinone was used as an inducer to prepare a mouse model of leukoderma to test the effect of the test substance on hair regeneration.

[0052] 1.1 Experimental animals 4-5 week old male C57BL / 6J mice were purchased from Guangdong Yaokang Biotechnology Co., Ltd. with the animal review ethics number G2024124.

[0053] 1.2 Grouping and Dosing The experimental groups and drug administration are shown in Table 4: Table 4 Experimental groups

[0054] The specific process is as follows: (1) Male C57BL / 6J mice of appropriate age were selected and housed in a barrier facility with free access to food and water. The experiment was started after adaptive feeding (approximately 7 days); (2) After the adaptive feeding of C57BL / 6J mice was completed, they were divided into four groups: blank control group (NC), model control group (M), experimental sample group (S1), and experimental sample group (S2), and ear-tagged. (3) An area of ​​approximately 2 cm × 2 cm was selected from the back of the mouse as the test area and shaved; (4) Mice in the model control group (M), experimental sample group (S1), and experimental sample group (S2) were given an appropriate amount of hydroquinone cream and evenly applied to the test area every day. After a certain period of time, it was washed off with saline and then an appropriate amount of sample was applied (application method: 200uL of sample was added to the center of the experimental area (3cm×3cm), and then massaged from the inside to the outside in a spiral manner to apply it evenly). The negative control group (NC) was given normal saline applied to the test area every day. (5) Observe the physical signs and behavioral changes of mice daily, such as lethargy, sparse hair, appetite, and water intake; take photos and record the hair condition of the test area every 7 days; (6) The model was continued until the hair in the test area of ​​the mice in group M showed obvious whitening compared with that in the mice in group NC.

[0055] 1.3 Sampling, testing and analysis (a) Mice were sacrificed, and photos were taken to record the hair condition of the test area.

[0056] (b) Mice with obvious differences in each group were selected and their hair and hair follicles were plucked and observed under a microscope.

[0057] (c) Newly grown hair from the test area of ​​each group of mice was cut and melanin was extracted (Melanin extraction method: weigh an appropriate amount of hair from the test area of ​​mice and place it in a centrifuge tube. Add concentrated hydrochloric acid at a ratio of 1 mg / 300 μL and soak until the mouse hair is fully dissolved (for more than 5 days). Then, aspirate the extract and measure OD490.) Spectrophotometric values ​​were measured to compare the relative melanin content of each molecular group.

[0058] (d) The skin of the test area of ​​each group of mice was removed and fixed in 4% paraformaldehyde before being embedded in paraffin. The skin was sectioned and stained with ferrous sulfate for melanin. The melanin content of the skin hair follicles and the basal melanocytes were observed under a microscope.

[0059] 1.4 Result calculation and judgment method 1.4.1 Result calculation (a) Photographs were taken to record the hair condition of the test area, and the degree of hair whitening in the test area of ​​mice in each group was observed and compared.

[0060] (b) The melanin content in the hair follicles and hair of the test areas of each group of mice was observed and compared under a microscope.

[0061] (c) Hair samples from the test area of ​​mice were dissolved and the OD value of the solution was measured at a wavelength of 490 nm. The average OD value of each group of samples was calculated.

[0062] Melanin relative content (%) = OD 490e / OD 490b ×100% Where: OD 490e —Absorbance of test sample and blank control group; OD 490b —Absorbance of model control group.

[0063] (d) The skin structure, hair follicle morphology, and melanocytes were observed under a microscope after melanin ferrous sulfate staining in sections of each group.

[0064] 1.4.2 Determination method Under the conditions of this experiment, by observing the pictures of the test area of ​​mice, if the hair of the test area of ​​the model control group (M) mice shows obvious whitening compared with the blank control group (NC), then the test system is normal and meets the requirements; if the degree of whitening of the hair of the test area of ​​the sample group mice is lower than that of the model control group mice, it is considered that the sample can promote the production of melanin in the mouse hair and has the effect of promoting the conversion of white hair to black.

[0065] Under the conditions of this experiment, by observing the hair and hair follicles in the test area of ​​mice under a microscope, if the hair and hair follicles in the test area of ​​mice in the model control group (M) show obvious whitening compared with the blank control group (NC), then the test system has no abnormalities and meets the requirements; if the degree of whitening of the hair and hair follicles in the test area of ​​mice in the sample group is lower than that of mice in the model control group, it is considered that the sample can promote the production of melanin in mouse hair and has the effect of promoting the conversion of white hair to black.

[0066] Under the conditions of this experiment, by extracting the hair melanin of the test area of ​​each group of mice, if the hair melanin content of the test area of ​​the model control group (M) mice is significantly reduced compared with the blank control group (NC), then the test system has no abnormalities and meets the requirements; if the hair melanin content of the test area of ​​the sample group mice is significantly higher than that of the model control group mice, it is considered that the sample can promote the production of hair melanin in mice and has the effect of promoting the transformation of white hair into black.

[0067] Under the conditions of this experiment, the skin sections of the test area of ​​each group of mice were stained with ferrous sulfate method. If the melanin content of the hair follicles in the test area of ​​the model control group (M) mice was significantly reduced compared with the blank control group (NC), then the test system was normal and met the requirements; if the melanin content of the hair follicles in the test area of ​​the sample group mice was significantly higher than that of the model control group mice, or the basal melanocytes in the test area of ​​the sample group mice were higher than that of the model control group mice, then it was considered that the sample could promote the production of melanin in the mouse hair and had the effect of promoting the transformation of white hair into black.

[0068] 1.5 Statistical analysis The experimental data were processed using IBM SPSS Statistics 23 software and plotted using GraphPad Prism 7.00 software. For numerical variables, t-test was used for comparison between groups. p A difference less than 0.05 was considered significant.

[0069] 1.6 Test results and analysis 1.6.1 Albinism status of the test area See the results Figure 1 By observing the pictures of the test areas of mice, compared with the blank control group (NC), the hair of the test area of ​​the mice in the model control group (M) showed obvious whitening compared with the NC group mice. There was no abnormality in the test system and it met the requirements; the degree of whitening of the hair in the test area of ​​the mice in the S1 and S2 groups was lower than that in the model control group mice.

[0070] 1.6.2 Microscopic observation of hair and hair follicles in the test area See the results Figure 2-Figure 3 By observing the hair and hair follicles in the test area of ​​mice under a microscope, compared with the blank control group (NC), the hair and hair follicles in the test area of ​​mice in the model control group (M) showed obvious whitening compared with the NC group mice. There was no abnormality in the test system and it met the requirements; the degree of whitening of the hair and hair follicles in the test area of ​​mice in the S1 and S2 groups was significantly lower than that in the model control group mice.

[0071] 1.6.3 Statistical analysis of relative melanin content in hair of the test area The results are shown in Table 5: Table 5 Statistical analysis results of relative content of melanin in hair of mice tested area

[0072] The results showed that (Table 5, Figure 4 ), by extracting the hair melanin of the test area of ​​each group of mice, compared with the blank control group (NC), the hair melanin content in the test area of ​​the model control group (M) mice was significantly reduced, and there was no abnormality in the test system, which met the requirements; the relative content of hair melanin in the test area of ​​the mice in the S1 and S2 groups was 176.35% and 199.38%, respectively, which were significantly higher than those in the model control group mice.

[0073] 1.6.4 Results of ferrous sulfate staining of the test area skin See the results Figure 5-Figure 6 By staining the skin sections of the test areas of mice in each group with the ferrous sulfate method, the results showed that compared with the blank control group (NC), the melanin content of the hair follicles in the test area of ​​the model control group (M) mice was significantly reduced, and there was no abnormality in the test system, which met the requirements; the melanin content of the hair follicles in the test areas of the mice in the S1 and S2 groups was significantly higher than that in the model control group, and the number and activity of basal melanocytes in the test areas of the mice in the S1 and S2 groups were higher than those in the model control group.

[0074] In summary, under the test conditions of this test, both S1 and S2 samples can significantly promote the production of melanin in the hair of mice with hydroquinone-induced leukoencephalopathy, and have the effect of promoting the transformation of white hair to black.

[0075] Comparative Example A comparative example was set up with reference to Example 1. The differences between the comparative example and Example 1 are shown in Table 6. Then, the melanin content was measured with reference to the effect example. The results are shown in Table 7.

[0076] Table 6

[0077] Table 7

[0078] The above results show that compared with the model group, samples 1-5 of Comparative Examples significantly increased the melanin content in mouse hair (p < 0.05). Compared with the samples of the present invention's formula, the relative melanin content was lower than the test results of samples S1 and S2. This indicates that the active ingredients in the present invention's formula promote melanin production through different pathways or targets, rather than acting alone, and that the combination of ingredients synergizes to enhance efficacy.

[0079] The above detailed description is a specific description of one feasible embodiment of the present invention and is not intended to limit the scope of the present invention. It should be noted that any equivalent implementation or modification that does not depart from the present invention should be included within the scope of the technical solution of the present invention. Therefore, the scope of protection of the patent of this invention should be based on the attached requirements.

Claims

1. A composition for turning white hair into black hair, characterized in that: The composition includes Ononopus rubrum root extract, Oat nigra seed extract, Emblica officinalis fruit extract and glycoprotein.

2. The composition according to claim 1, characterized in that The composition may also include one or more of a thickener, a humectant, or a preservative.

3. The composition according to claim 2, characterized in that The thickener is one or more of ammonium acryloyldimethyltaurate / VP copolymer, xanthan gum, carrageenan, guar gum, gum arabic, hydroxyethyl cellulose, hydroxypropyl methylcellulose, carbomer, sodium polyacrylate, polyvinyl alcohol or polyethylene glycol; The moisturizing agent is one or more of butylene glycol, glycerin, propylene glycol, sodium hyaluronate, trehalose, betaine, sorbitol, mannitol or sodium pyrrolidone carboxylate; The preservative is one or more of phenoxyethanol, ethylhexylglycerin, caprylyl glycol, pentylene glycol or 1,2-hexanediol.

4. The composition according to any one of claims 1 to 3, characterized in that The composition is composed of Ononopus rubrum root extract, Oat nigra seed extract, Emblica officinalis fruit extract, Zingiber officinale root extract, Allantoin, Bisabolol, Panthenol, Glycoprotein, Ammonium Acryloyldimethyltaurate / VP Copolymer, Butylene Glycol, Glycerin, Propanediol, Propylene Glycol, Sodium Hyaluronate, Trehalose, Betaine, Phenoxyethanol, and Ethylhexylglycerin.

5. The composition according to claim 4, characterized in that The composition consists, by weight percentage, of 0.013-0.015% of red onion root extract, 0.013-0.015% of black oat seed extract, 0.030-0.035% of emblica fruit extract, 0.000006-0.000008% of glycoprotein, 0.1-0.2% of allantoin, 0.4-0.6% of ammonium acryloyldimethyltaurate / VP copolymer, 2-3% of butylene glycol, 1.0-1.2% of glycerin, 1.0-1.5% of trehalose, 0.5-1.0% of betaine, 0.45-0.48% of phenoxyethanol and 0.05-0.08% of ethylhexylglycerin, with the balance being water.

6. The composition according to claim 5, characterized in that The composition consists of, by weight percentage, 0.013% of red onion root extract, 0.013% of black oat seed extract, 0.030% of emblica fruit extract, 0.000006% glycoprotein, 0.1% allantoin, 0.6% ammonium acryloyldimethyltaurate / VP copolymer, 2% butylene glycol, 1% glycerin, 1% trehalose, 0.5% betaine, 0.45% phenoxyethanol and 0.05% ethylhexylglycerin, with the balance being water.

7. The composition according to claim 5, characterized in that The composition consists of, by weight percentage, 0.015% of red onion root extract, 0.015% of black oat seed extract, 0.035% of emblica fruit extract, 0.000008% glycoprotein, 0.2% allantoin, 0.4% ammonium acryloyldimethyltaurate / VP copolymer, 3% butylene glycol, 1.2% glycerin, 1.5% trehalose, 1% betaine, 0.48% phenoxyethanol and 0.08% ethylhexylglycerin, with the balance being water.

8. The method for preparing the composition according to any one of claims 1 to 7, characterized in that: The following steps are involved: S1. Accurately weigh water and ammonium acryloyldimethyltaurate / VP copolymer and add them to the main beaker. Stir evenly after swelling to obtain A. S2. Accurately weigh and sequentially add glycerol, butylene glycol, betaine, trehalose, and allantoin to solution A until completely dissolved to obtain solution B. S3. Add the red onion root extract, black oat seed extract, Kerascalp emblica fruit extract, Wisegrade glycoprotein, phenoxyethanol and ethylhexylglycerin to B in sequence and mix well.

9. Use of the composition according to any one of claims 1 to 7 or the preparation method according to claim 8 in preparing products for promoting black hair or preventing gray hair.

10. The use according to claim 9, characterized in that The products include head care products or medicines.

11. The use according to claim 10, characterized in that The head care product is scalp essence, scalp scrub, scalp massage oil, scalp spray, conditioner, hair mask, hair care essential oil, hair care spray, shampoo, shampoo soap, dry shampoo spray, hair gel, hair wax, hair mud or styling spray.

12. A head care product, characterized in that: The head care product comprises the composition according to any one of claims 1 to 7.

13. The head care product according to claim 12, characterized in that The composition is the sole or main active ingredient of a head care product.

14. The head care product according to claim 12 or 13, characterized in that The head care product may further comprise other ingredients that improve product texture, stability, sensory experience or auxiliary efficacy.

15. A drug, characterized in that The medicine comprises the composition according to any one of claims 1 to 7.

16. The drug according to claim 15, characterized in that The drug also includes pharmaceutically acceptable excipients.

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