Oil-soluble anti-wrinkle firming composition containing glassine

Abstract

The invention relates to the technical field of anti-wrinkle firming compositions. The oil-soluble anti-wrinkle and firming composition is prepared from the following raw materials in parts by weight: 60 to 80 parts of oil-soluble botryine, 10 to 20 parts of caprylic / capric triglyceride, 10 to 20 parts of additive liquid, 10 to 20 parts of mixed essential oil, 3 to 5 parts of acetyl hexapeptide-8, 2 to 4 parts of chrysanthemum extract, 2 to 4 parts of carnosine, 1 to 2 parts of ergothioneine and 1 to 2 parts of methyl p-hydroxybenzoate. According to the anti-wrinkle and firming composition, the anti-wrinkle and firming effects are achieved after the anti-wrinkle and firming composition is smeared, meanwhile, the comfort degree of skin is improved, in the second mixture component, daidzin in the soy isoflavone can be converted into an aglycone form which is high in biological activity and easier to absorb and utilize by the skin through beta-glucosidase, and therefore the anti-wrinkle and firming composition has a good anti-wrinkle and firming effect. The skin absorption efficiency of the anti-wrinkle and firming composition after use is improved, so that the use effect of the anti-wrinkle and firming composition is improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of anti-wrinkle firming composition, in particular to an oil-soluble anti-wrinkle firming composition containing bovine growth factors. BACKGROUND

[0002] Anti-wrinkle firming composition is a kind of skin care product that improves skin wrinkles and tightness through the synergistic effect of multiple ingredients.

[0003] In the prior art, during the user experience of using the anti-wrinkle firming composition, it is found that the anti-wrinkle firming composition has the problems of skin heat and poor absorption efficiency after application, which affects the use effect of the anti-wrinkle firming composition. Based on this, the present application provides an oil-soluble anti-wrinkle firming composition containing bovine growth factors. SUMMARY

[0004] The purpose of the present application is to provide an oil-soluble anti-wrinkle firming composition containing bovine growth factors. The anti-wrinkle firming composition prepared by the present application not only has good anti-wrinkle performance, but also has excellent application comfort, effectively improving the use performance of the anti-wrinkle firming composition.

[0005] To achieve the above-mentioned purpose, the present application provides the following technical scheme:

[0006] In a first aspect, the present application provides an oil-soluble anti-wrinkle firming composition containing bovine growth factors, comprising the following raw materials by weight: 60-80 parts of oil-soluble bovine growth factors, 10-20 parts of capric and caprylic acid glycerol triester, 10-20 parts of additive liquid, 10-20 parts of mixed essential oil, 3-5 parts of acetyl hexapeptide-8, 2-4 parts of spilanthes extract, 2-4 parts of myo-inositol, 1-2 parts of ergothioneine, and 1-2 parts of methyl paraben.

[0007] The additive liquid is prepared by the following method:

[0008] S1: First mixture preparation, the raw materials of the first mixture include shaddock essential oil, mixed liquid, glycerol, and treatment agent. The raw materials of the mixed liquid include dried tea leaves, lignin, and konjac glucomannan. The raw materials of the treatment agent include cellulase, pectinase, asiaticoside, and deionized water.

[0009] S2: Second mixture preparation, the raw materials of the second mixture include beta-glucosidase and soybean isoflavone. The mass of the second mixture is 10-20% of the mass of the first mixture.

[0010] S3: Mixing treatment, the first mixture and the second mixture are mixed to prepare the additive liquid.

[0011] Further, the method for preparing the first mixture is as follows: pomelo essential oil, mixed solution, glycerol are added into a water bath, the water bath is set to be heated to 55-65℃, the water bath is connected to a magnetic stirrer, the magnetic stirrer is set to rotate at a speed of 200-300r / min, the constant temperature stirring treatment is carried out for 20-40min, the slurry is prepared, the slurry is added into a mixer, a treating agent is added into the mixer, the mixer is set to stir at a speed of 60-100r / min for 6-10min, the obtained product is placed in a dark environment at 28-32℃ for 4-8d, the obtained product is subjected to high temperature sterilization treatment, then centrifugal treatment is carried out, the supernatant is taken, and the first mixture is prepared.

[0012] Further, the mass ratio of pomelo essential oil, mixed solution and glycerol is 1:(0.6-0.8):(0.1-0.2), and the mass of the treating agent is 20-30% of the mass of the slurry.

[0013] Further, the treating agent is prepared by mixing cellulase, pectinase, asiaticoside and deionized water, and the mass ratio of cellulase, pectinase, asiaticoside and deionized water is 1:(0.4-0.6):(0.2-0.4):(3-5).

[0014] Further, the mixed solution is prepared by the following method: dried tea leaves are fed into a powder mill, the powder mill is set to process at a speed of 400-600r / min for 8-10min to obtain coarse powder, the coarse powder is added into a mixer, lignin and konjac glucomannan are added into the mixer, and stirring treatment is carried out at a speed of 120-160r / min for 20-30min to obtain powder, the powder is subjected to soaking treatment with boiling water, the mass of the boiling water is 8-10 times of the mass of the powder, and the soaking time is 20-30min, after the soaking treatment is completed, filtration is carried out to obtain liquid material and solid material respectively, the solid material is subjected to repeated soaking and filtration treatment for 2-4 times, and the liquid material obtained through multiple treatments is combined to obtain the mixed solution, wherein the mass ratio of coarse powder, lignin and konjac glucomannan is 1:(0.06-0.08):(0.08-0.12).

[0015] Further, the second mixture is prepared by the following method: β-glucosidase is subjected to ultrasonic reaction at pH 4.8, temperature 45-55℃ and power 200-300W for 30-40min, the obtained product is added into a reaction kettle, soybean isoflavone is added into the reaction kettle, the reaction kettle is set to have a temperature of 45-55℃ and a stirring speed of 200-300r / min, constant temperature stirring treatment is carried out for 20-30min, the obtained product is subjected to boiling water bath treatment for 4-6h, and the second mixture is prepared.

[0016] Further, the mass ratio of β-glucosidase and soybean isoflavone is 1:(4-6).

[0017] Further, the mixing method is that the first mixture and the second mixture are added into a mixer, the mixer is set to stirring treatment at 300-500 r / min for 30-40 min, and the additive liquid is prepared.

[0018] Further, the mixed essential oil is prepared by mixing lavender essential oil, tea tree essential oil, grape seed oil and blue gum leaf oil, and the mass ratio of the lavender essential oil, the tea tree essential oil, the grape seed oil and the blue gum leaf oil is 1:(0.2-0.4):(0.6-0.8):(0.4-0.6).

[0019] In the second aspect, the application further provides a preparation method of the oil-soluble anti-wrinkle and firming composition containing a Bose factor, which comprises the following steps: weighing the oil-soluble Bose factor, capric and caprylic triglyceride, additive liquid, mixed essential oil, acetyl hexapeptide-8, spilanthes acuta extract, carnosine, ergothioneine and methyl paraben according to requirements and adding them into a mixer, setting the mixer to stirring treatment at 100-200 r / min for 40-60 min, and performing high-temperature sterilization treatment on the obtained product to prepare the anti-wrinkle and firming composition.

[0020] Compared with the prior art, the application has the following beneficial effects:

[0021] 1. In the preparation process of the anti-wrinkle and firming composition, the oil-soluble Bose factor as a basic component can promote the synthesis of glycosaminoglycan and collagen, improve skin elasticity and wrinkles, in the component addition system of the additive liquid, the tea leaves can utilize the rich polyphenolic compounds to play the roles of antioxidation, anti-inflammation and promotion of collagen synthesis, so that the anti-wrinkle and firming composition after application can play the roles of anti-wrinkle and firming and improve the comfort of the skin, in the second mixture component, the beta-glucosidase can convert soybean glycosides in soybean isoflavones into aglycone forms with higher biological activity and easier absorption by the skin, so as to improve the skin absorption efficiency after use of the anti-wrinkle and firming composition, thereby improving the use effect of the anti-wrinkle and firming composition.

[0022] 2. In the application, the enzymatic treatment of the slurry by the treatment agent can destroy the cell wall structure of the tea leaf cells, maximize the extraction and release of the antioxidant polyphenolic components in the tea leaves, thereby effectively improving the use effect of the anti-wrinkle and firming composition, and the konjac gum can form a sticky state at the oil-water interface, so that the anti-wrinkle and firming composition is easy to spread and apply, ensures that the effective components are stably left at the application position, and further improves the use effect of the anti-wrinkle and firming composition. BRIEF DESCRIPTION OF DRAWINGS

[0023] Figure 1 The application provides a flowchart of the oil-soluble anti-wrinkle and firming composition containing a Bose factor. DETAILED DESCRIPTION

[0024] With reference to the embodiments of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described, obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of the present application.

[0025] It should be noted that the raw materials used in the following examples are all commercially available.

[0026] Example 1:

[0027] Preparation of raw materials: 60 parts of oil-soluble bovine growth factors, 10 parts of capric and caprylic acid glycerin ester, 10 parts of additive liquid, 10 parts of mixed essential oil, 3 parts of acetyl hexapeptide-8, 2 parts of spilanthes acmella extract, 2 parts of lycium barbarum polypeptide, 1 part of ergothioneine, and 1 part of methyl paraben;

[0028] The mixed essential oil is prepared by mixing lavender essential oil, tea tree essential oil, grape seed oil and blue eucalyptus leaf oil, and the mass ratio of the lavender essential oil, tea tree essential oil, grape seed oil and blue eucalyptus leaf oil is 1:0.2:0.6:0.4.

[0029] Preparation of additive liquid:

[0030] S1: Preparation of the first mixture, the raw materials of the first mixture include grapefruit essential oil, mixed liquid, glycerol and treatment agent, the raw materials of the mixed liquid include dried tea leaves, lignin and konjac glucomannan, and the raw materials of the treatment agent include cellulase, pectinase, asiaticoside and deionized water;

[0031] The method for preparing the first mixture is as follows: the grapefruit essential oil, mixed liquid and glycerol are added into a water bath kettle, the water bath kettle is set to be heated to 55℃, the water bath kettle is connected with a magnetic stirrer, the magnetic stirrer is set to rotate at a speed of 200r / min, and the slurry is prepared by constant temperature stirring treatment for 20 min, then the slurry is added into a mixer, the treatment agent is added into the mixer, the mixer is set to stir at a speed of 60r / min for 6 min, the obtained product is placed in a dark environment at 28℃ for 4 days, the obtained product is subjected to high temperature sterilization treatment, and then centrifugal treatment is performed, the supernatant is taken, and the first mixture is prepared, wherein the mass ratio of the grapefruit essential oil, mixed liquid and glycerol is 1:0.6:0.1, and the mass of the treatment agent is 20% of the mass of the slurry;

[0032] The treatment agent is prepared by mixing cellulase, pectinase, asiaticoside and deionized water, and the mass ratio of the cellulase, pectinase, asiaticoside and deionized water is 1:0.4:0.2:3.

[0033] The mixed solution is prepared by the following method: dry tea leaves are fed into a powder mill, the powder mill is set to 400 r / min for 8 min to obtain coarse powder, the coarse powder is added into a mixer, lignin and konjac glucomannan are added into the mixer, and the mixer is set to 120 r / min for stirring for 20 min to obtain powder, the powder is subjected to soaking treatment with boiling water, the mass of the boiling water is 8 times that of the powder, the soaking time is 20 min, after the soaking treatment is completed, filtration is performed to obtain liquid material and solid material respectively, the solid material is subjected to repeated soaking and filtration treatment for 2 times, and the liquid materials obtained through multiple treatments are combined to obtain the mixed solution, wherein the mass ratio of the coarse powder, the lignin and the konjac glucomannan is 1:0.06:0.08.

[0034] S2: second mixture preparation, the raw materials of the second mixture include β-glucosidase and soy isoflavone, and the mass of the second mixture is 10% of the mass of the first mixture;

[0035] The second mixture is prepared by the following method: β-glucosidase is subjected to ultrasonic reaction at pH 4.8, a temperature of 45°C and a power of 200 W for 30 min, the obtained product is added into a reaction kettle, soy isoflavone is added into the reaction kettle, the reaction kettle is set to a temperature of 45°C and a stirring speed of 200 r / min, and the obtained product is subjected to constant-temperature stirring treatment for 20 min, and then boiling water bath treatment for 4 h to obtain the second mixture, wherein the mass ratio of the β-glucosidase and the soy isoflavone is 1:4.

[0036] S3: mixing treatment, the first mixture and the second mixture are subjected to mixing treatment to obtain an additive solution;

[0037] The mixing treatment method is as follows: the first mixture and the second mixture are added into a mixer, the mixer is set to 300 r / min for stirring treatment for 30 min to obtain the additive solution;

[0038] Product preparation: oil-soluble bovine sirtuins, capric and caprylic triglyceride, the additive solution, mixed essential oil, acetyl hexapeptide-8, chrysanthemum parthenium extract, carnosine, ergothioneine and methyl paraben are weighed as required and added into a mixer, the mixer is set to 100 r / min for stirring treatment for 40 min, and the obtained product is subjected to high-temperature sterilization treatment to obtain an anti-wrinkle firming composition.

[0039] Example two:

[0040] Raw material preparation: 70 parts of oil-soluble bovine sirtuins, 15 parts of capric and caprylic triglyceride, 15 parts of the additive solution, 15 parts of mixed essential oil, 4 parts of acetyl hexapeptide-8, 3 parts of chrysanthemum parthenium extract, 3 parts of carnosine, 1.5 parts of ergothioneine and 1.5 parts of methyl paraben;

[0041] The mixed essential oil is prepared by mixing lavender essential oil, tea tree essential oil, grape seed oil and blue eucalyptus leaf oil, and the mass ratio of the lavender essential oil, the tea tree essential oil, the grape seed oil and the blue eucalyptus leaf oil is 1:0.3:0.7:0.5;

[0042] The preparation of the additive solution:

[0043] S1: The first mixture is prepared, and the raw materials of the first mixture include grapefruit essential oil, a mixed solution, glycerol and a treatment agent, the raw materials of the mixed solution include dried tea leaves, lignin and konjac glucomannan, and the raw materials of the treatment agent include cellulase, pectinase and asiaticoside, and deionized water;

[0044] The method for preparing the first mixture is as follows: the grapefruit essential oil, the mixed solution and the glycerol are added into a water bath kettle, the water bath kettle is set to be heated to 60 DEG C, the water bath kettle is connected with a magnetic stirrer, the magnetic stirrer is set to rotate at a speed of 250 r / min, and the slurry is prepared by constant temperature stirring treatment for 30 min; the slurry is added into a mixer, the treatment agent is added into the mixer, the mixer is set to stir at a speed of 80 r / min for 8 min, the obtained product is placed in a dark environment at 30 DEG C for 6 days, the obtained product is subjected to high-temperature sterilization treatment, and then centrifugal treatment is performed, the supernatant is taken, and the first mixture is prepared, wherein the mass ratio of the grapefruit essential oil, the mixed solution and the glycerol is 1:0.7:0.15, and the mass of the treatment agent is 25% of the mass of the slurry;

[0045] The treatment agent is prepared by mixing cellulase, pectinase, asiaticoside and deionized water, and the mass ratio of the cellulase, the pectinase, the asiaticoside and the deionized water is 1:0.5:0.3:4;

[0046] The mixed solution is prepared by the following method: the dried tea leaves are sent into a powder mill, the powder mill is set to be treated at a speed of 500 r / min for 9 min to obtain coarse powder, the coarse powder is added into a mixer, the mixer is set to stir at a speed of 140 r / min for 25 min after lignin and konjac glucomannan are added into the mixer to obtain powder, the powder is subjected to soaking treatment with boiling water, the mass of the boiling water is 9 times of the mass of the powder, the soaking time is 25 min, and after the soaking treatment is completed, the liquid material and the solid material are obtained by filtration, the solid material is continuously subjected to repeated soaking and filtration treatment for 3 times, and the liquid materials obtained by multiple treatments are combined to obtain the mixed solution, wherein the mass ratio of the coarse powder, the lignin and the konjac glucomannan is 1:0.07:0.1;

[0047] S2: The second mixture is prepared, and the raw materials of the second mixture include beta-glucosidase and soybean isoflavone. The mass of the second mixture is 15% of the mass of the first mixture;

[0048] The second mixture is prepared by the following method: ultrasonic reaction of the beta-glucosidase at pH 4.8, a temperature of 50 DEG C and a power of 250 W for 35 min, adding the obtained product into a reaction kettle, adding soy isoflavones into the reaction kettle, setting the temperature of the reaction kettle to 50 DEG C, setting the stirring speed of the reaction kettle to 250 r / min, constant temperature and stirring treatment for 25 min, boiling water bath treatment of the obtained product for 5 h, to obtain the second mixture, wherein the mass ratio of the beta-glucosidase and the soy isoflavones is 1:5;

[0049] S3: mixing treatment, the first mixture and the second mixture are mixed to obtain the additive liquid;

[0050] The method of the mixing treatment is: the first mixture and the second mixture are added into a mixer, the mixer is set to stirring treatment at 400 r / min for 35 min to obtain the additive liquid;

[0051] Product preparation: oil-soluble bovine, capric and caprylic triglyceride, additive liquid, mixed essential oil, acetyl hexapeptide-8, spilanthes acuta extract, carnosine, ergothioneine, methyl paraben are weighed according to the requirements and added into a mixer, the mixer is set to stirring treatment at 150 r / min for 50 min, the obtained product is subjected to high-temperature sterilization treatment to obtain the anti-wrinkle and firming composition.

[0052] Example three:

[0053] Raw material preparation: 80 parts of oil-soluble bovine, 20 parts of capric and caprylic triglyceride, 20 parts of additive liquid, 20 parts of mixed essential oil, 5 parts of acetyl hexapeptide-8, 4 parts of spilanthes acuta extract, 4 parts of carnosine, 2 parts of ergothioneine, and 2 parts of methyl paraben;

[0054] The mixed essential oil is prepared by mixing lavender essential oil, tea tree essential oil, grape seed oil and blue eucalyptus leaf oil, and the mass ratio of the lavender essential oil, the tea tree essential oil, the grape seed oil and the blue eucalyptus leaf oil is 1:0.4:0.8:0.6;

[0055] Additive liquid preparation:

[0056] S1: first mixture preparation, the raw materials of the first mixture include yuxiang essential oil, mixed liquid, glycerol and treatment agent, the raw materials of the mixed liquid include dried tea leaves, lignin and konjac glucomannan, and the raw materials of the treatment agent include cellulase, pectinase, asiaticoside and deionized water;

[0057] The method for preparing the first mixture is as follows: the grapefruit essential oil, the mixed solution, and glycerol are added into a water bath kettle, the water bath kettle is set to be heated to 65 DEG C, the water bath kettle is connected with a magnetic stirrer, the magnetic stirrer is set to rotate at a speed of 300 r / min, the constant temperature stirring treatment is performed for 40 min, the slurry is prepared, the slurry is added into a mixer, a treating agent is added into the mixer, the mixer is set to stir at a speed of 100 r / min for 10 min, the obtained product is placed in a dark environment at 32 DEG C for 8 days, the obtained product is subjected to high-temperature sterilization treatment, and then is subjected to centrifugal treatment, the supernatant is taken, and the first mixture is prepared, wherein the mass ratio of the grapefruit essential oil, the mixed solution, and glycerol is 1:0.8:0.2, and the mass of the treating agent is 30% of the mass of the slurry.

[0058] The treating agent is prepared by mixing the cellulase, the pectinase, the asiaticoside, and the deionized water, and the mass ratio of the cellulase, the pectinase, the asiaticoside, and the deionized water is 1:0.6:0.4:5.

[0059] The mixed solution is prepared by the following method: the dried tea leaves are fed into a powder mill, the powder mill is set to be treated at a speed of 600 r / min for 10 min to obtain coarse powder, the coarse powder is added into a mixer, the mixer is added with the lignin and the konjac glucomannan, and is set to be stirred at a speed of 160 r / min for 30 min to obtain powder, the powder is subjected to soaking treatment with boiling water, the mass of the boiling water is 10 times of the mass of the powder, the soaking time is 30 min, and after the soaking treatment is completed, the liquid material and the solid material are obtained by filtration, the solid material is continuously subjected to repeated soaking and filtration treatment for 4 times, and the liquid materials obtained by multiple times of treatment are combined to prepare the mixed solution, wherein the mass ratio of the coarse powder, the lignin, and the konjac glucomannan is 1:0.08:0.12.

[0060] S2: the second mixture is prepared, the raw materials of the second mixture include the β-glucosidase and the soybean isoflavone, and the mass of the second mixture is 20% of the mass of the first mixture;

[0061] The second mixture is prepared by the following method: the β-glucosidase is subjected to ultrasonic reaction at pH 4.8, a temperature of 55 DEG C, and a power of 300 W for 40 min, the obtained product is added into a reaction kettle, the reaction kettle is added with the soybean isoflavone, the reaction kettle is set to be heated to 55 DEG C, and is stirred at a speed of 300 r / min for 30 min, and the obtained product is subjected to boiling water bath treatment for 6 h to prepare the second mixture, wherein the mass ratio of the β-glucosidase and the soybean isoflavone is 1:6.

[0062] S3: the mixing treatment, the first mixture and the second mixture are subjected to mixing treatment to prepare the adding liquid;

[0063] The method for the mixing treatment is as follows: the first mixture and the second mixture are added into a mixer, the mixer is set to be stirred at a speed of 500 r / min for 40 min to prepare the adding liquid;

[0064] Product preparation: the oil-soluble bovine growth factor, capric caprylic triglyceride, additive liquid, mixed essential oil, acetyl hexapeptide-8, spilanthes acuta extract, carnosine, ergothioneine, methyl paraben were weighed as needed and added into a mixer, the mixer was set to 200 r / min stirring treatment for 60 min, the obtained product was subjected to high temperature sterilization treatment to prepare the anti-wrinkle firming composition.

[0065] Comparative Example 1, the difference between the comparative example 1 and example 1 is that the comparative example 1 does not contain the mixed liquid.

[0066] Comparative Example 2, the difference between the comparative example 2 and example 1 is that the comparative example 2 does not contain the first mixed material.

[0067] Comparative Example 3, the difference between the comparative example 3 and example 1 is that the comparative example 3 does not contain the second mixed material.

[0068] Comparative Example 4, the difference between the comparative example 4 and example 1 is that the comparative example 4 does not contain the additive liquid.

[0069] Performance test: the anti-wrinkle firming compositions prepared in example 1, example 2, example 3, comparative example 1, comparative example 2, comparative example 3 and comparative example 4 were subjected to performance test, and the obtained test data were recorded in the following table:

[0070] Detection item Number of wrinkle removal satisfaction Comfort score Example 1 46 4.8 Example 2 45 4.6 Example 3 43 4.6 Comparative Example 1 39 3.8 Comparative Example 2 33 3.2 Comparative Example 3 37 3.6 Comparative Example 4 28 2.8

[0071] In the performance test, 350 female volunteers aged 35-45 were recruited, and the 350 volunteers were evenly divided into 7 groups, and the anti-wrinkle firming compositions prepared in example 1, example 2, example 3, comparative example 1, comparative example 2, comparative example 3 and comparative example 4 were respectively distributed to the 7 groups of volunteers, and the anti-wrinkle firming compositions were evenly applied on the forehead and rubbed every night, and the use period was 60 d, and after the use period, the use of the volunteers was investigated, and the investigation content included the wrinkle removal state and the comfort degree score during application, and the score standard was 1-5 points, wherein 1 point was the worst and 5 points was the best.

[0072] It can be seen that the anti-wrinkle performance and application comfort of the anti-wrinkle firming compositions prepared in Comparative Examples 1, 2, 3 and 4 are lower than those in Example 1, 2 and 3; this shows that in the preparation of the anti-wrinkle firming composition, the oil-soluble bovine growth factor as the base component can promote the synthesis of glycosaminoglycan and collagen, improve the skin elasticity and wrinkle, in the component adding system of the additive liquid, the tea leaves can utilize the rich polyphenol compounds to play the roles of antioxidation, anti-inflammation and promotion of collagen synthesis, so that the anti-wrinkle firming composition after application can play the roles of anti-wrinkle firming and improve the skin comfort, in the second mixture component, the beta-glucosidase can convert the soybean glycoside in the soybean isoflavone into the aglycone form with higher biological activity and easier to be absorbed by the skin, so as to improve the skin absorption efficiency after use of the anti-wrinkle firming composition, thereby improving the use effect of the anti-wrinkle firming composition;

[0073] The enzymatic treatment of the slurry by the treatment agent can destroy the cell wall structure of the tea leaf cells, maximize the extraction and release of the antioxidant polyphenol components in the tea leaves, thereby effectively improving the use effect of the anti-wrinkle firming composition; the konjac gum can form a sticky state at the oil-water interface, so that the anti-wrinkle firming composition is easy to spread and apply, and the effective components are ensured to be stably left at the application position, thereby further improving the use effect of the anti-wrinkle firming composition.

[0074] It can be known from the comparison and analysis of the related data in the table that the anti-wrinkle firming composition prepared by the application not only has good anti-wrinkle performance, but also has excellent application comfort; this shows that the oil-soluble anti-wrinkle firming composition containing bovine growth factor provided by the application has a broader market prospect and is more suitable for promotion.

[0075] In the description of the present specification, the description of the terms "one embodiment", "example", "specific example" and the like means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are contained in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0076] The preferred embodiments of the application disclosed above are only used to help explain the application. The preferred embodiments do not describe all the details and limit the application to the specific embodiments described. Obviously, many modifications and changes can be made according to the content of the present specification. The present specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the application, so that those skilled in the art can well understand and utilize the application. The application is limited by the claims and their entire scope and equivalents.

Claims

1. An oil-soluble anti-wrinkle firming composition containing a bovine somatotropin, characterized in that: The method comprises the following raw materials by weight: 60-80 parts of oil-soluble bovine growth factors, 10-20 parts of capric and caprylic acid triglyceride, 10-20 parts of additive liquid, 10-20 parts of mixed essential oil, 3-5 parts of acetyl hexapeptide-8, 2-4 parts of spilanthes acuta extract, 2-4 parts of carnosine, 1-2 parts of ergothioneine, and 1-2 parts of methyl paraben; The additive liquid is prepared by the following method: S1: first mixture preparation, the raw materials of the first mixture include grapefruit essential oil, mixed liquid, glycerol, and treatment agent, the raw materials of the mixed liquid include dried tea leaves, lignin, and konjac glucomannan, and the raw materials of the treatment agent include cellulase, pectinase, and asiaticoside, and deionized water; S2: second mixture preparation, the raw materials of the second mixture include β-glucosidase and soybean isoflavone, and the mass of the second mixture is 10-20% of the mass of the first mixture; S3: mixing treatment, the first mixture and the second mixture are mixed to prepare the additive liquid.

2. The oil-soluble anti-wrinkle firming composition containing a bovine factor according to claim 1, characterized by, The method for preparing the first mixture is as follows: the grapefruit essential oil, the mixed liquid, and the glycerol are added into a water bath kettle, the water bath kettle is set to be heated to 55-65 ℃, the water bath kettle is connected with a magnetic stirrer, the magnetic stirrer is set to rotate at a speed of 200-300 r / min, and constant temperature stirring treatment is performed for 20-40 min to prepare a slurry, the slurry is added into a mixer, the treatment agent is added into the mixer, the mixer is set to stir at a speed of 60-100 r / min for 6-10 min, the obtained product is placed in a dark environment at 28-32 ℃ for 4-8 d, the obtained product is subjected to high-temperature sterilization treatment, and then centrifugal treatment is performed, the supernatant is taken, and the first mixture is prepared.

3. The oil-soluble anti-wrinkle firming composition containing a bovine factor according to claim 2, characterized by, The mass ratio of the grapefruit essential oil, the mixed liquid, and the glycerol is 1:(0.6-0.8):(0.1-0.2), and the mass of the treatment agent is 20-30% of the mass of the slurry.

4. The oil-soluble anti-wrinkle firming composition containing a bovine factor according to claim 2, characterized by, The treatment agent is prepared by mixing cellulase, pectinase, asiaticoside, and deionized water, and the mass ratio of the cellulase, the pectinase, the asiaticoside, and the deionized water is 1:(0.4-0.6):(0.2-0.4):(3-5).

5. The oil-soluble anti-wrinkle firming composition containing a bovine factor according to claim 2, characterized by, The mixed liquid is prepared by the following method: the dried tea leaves are sent into a powder mill, the powder mill is set to be treated at a speed of 400-600 r / min for 8-10 min to obtain coarse powder, the coarse powder is added into a mixer, lignin and konjac glucomannan are added into the mixer, and stirring treatment is performed at a speed of 120-160 r / min for 20-30 min to obtain powder, the powder is subjected to soaking treatment with boiling water, the mass of the boiling water is 8-10 times that of the powder, and the soaking time is 20-30 min, after the soaking treatment is completed, filtration is performed to obtain liquid material and solid material, the solid material is subjected to repeated soaking and filtration treatment for 2-4 times, and the liquid material obtained through multiple treatments is combined to prepare the mixed liquid, and the mass ratio of the coarse powder, the lignin, and the konjac glucomannan is 1:(0.06-0.08):(0.08-0.12).

6. The oil-soluble anti-wrinkle firming composition containing a bovine factor according to claim 1, wherein The second mixture is prepared by the following method: ultrasonic reaction of beta-glucosidase at pH 4.8, temperature 45-55 DEG C, power 200-300 W for 30-40 min, adding the obtained product into a reaction kettle, adding soy isoflavones into the reaction kettle, setting the temperature of the reaction kettle to 45-55 DEG C, setting the stirring speed to 200-300 r / min, constant temperature stirring treatment for 20-30 min, boiling water bath treatment of the obtained product for 4-6 h, to obtain the second mixture.

7. The oil-soluble anti-wrinkle firming composition containing a bovine factor according to claim 6, characterized by, The mass ratio of beta-glucosidase and soy isoflavones is 1:(4-6).

8. The oil-soluble anti-wrinkle firming composition containing a bovine factor according to claim 1, wherein The mixing method is as follows: adding the first mixture and the second mixture into a mixer, setting the mixer to 300-500 r / min stirring treatment for 30-40 min, to obtain the additive liquid.

9. The oil-soluble anti-wrinkle composition containing a bovine factor according to claim 1, wherein The mixed essential oil is prepared by mixing lavender essential oil, tea tree essential oil, grape seed oil and blue eucalyptus leaf oil, and the mass ratio of lavender essential oil, tea tree essential oil, grape seed oil and blue eucalyptus leaf oil is 1:(0.2-0.4):(0.6-0.8):(0.4-0.6).

10. A process for the preparation of an oil-soluble anti-wrinkle firming composition containing a bovine somatotropin according to any one of claims 1 to 9, characterized in that, The method comprises the following steps: weighing oil-soluble bovine sirtuins, capric acid and capric acid triglyceride, additive liquid, mixed essential oil, acetyl hexapeptide-8, thousand-day chrysanthemum extract, carnosine, ergothioneine and methyl paraben according to the requirement, adding them into a mixer, setting the mixer to 100-200 r / min stirring treatment for 40-60 min, high-temperature sterilization treatment of the obtained product, to obtain the anti-wrinkle firming composition.

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