Intelligent solution concentrating and filling equipment

Abstract

The invention discloses intelligent solution concentrating and filling equipment which comprises a control module, a packaging module, an evaporation assembly provided with an evaporation tank, an extraction pump, a final liquid tank and a distribution pump. The extraction pump is connected with the evaporation tank and the final liquid tank and is used for extracting the evaporated and concentrated solution to the final liquid tank; the distribution pump is connected with the final liquid tank and matched with the packaging module, and the solution in the final liquid tank is conveyed to the packaging module to be packaged; the final liquid tank is provided with a final liquid measuring device for measuring the volume of the solution; the control module is connected with the evaporation assembly, the extraction pump, the distribution pump, the final liquid measuring device and the packaging module; after the control module sets the solution filling quantity, the distribution pump is controlled to carry out average distribution according to the filling quantity according to the solution volume fed back by the final solution measuring device, and the packaging module is controlled to carry out concentrated solution packaging according to the quantity. The problems that traditional concentration filling equipment is low in precision, poor in efficiency, high in manual dependence and the like are systematically solved through intelligent regulation and control of the control module, and the production efficiency and the product quality of liquid medicine preparations are remarkably improved.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical preparation production and processing, and more specifically, to a solution intelligent concentration and filling equipment. Background Technology

[0002] Medicinal liquids are active liquids obtained from natural medicinal materials (such as plants, animals, and minerals) through processes such as extraction, decoction, or osmosis. They are widely used in the pharmaceutical, health product, and food industries. Their core components include alkaloids, polysaccharides, volatile oils, and other effective substances, but they typically have a high water content (70%-90%). High water content can cause the following problems: 1. Poor user experience: Water dilutes the effective ingredients, resulting in reduced efficacy for the same volume, requiring more liquid to reach the required dosage. Overdose can easily cause bloating, nausea, and other physiological discomfort. 2. High storage risk: Moisture creates a suitable environment for the growth of microorganisms (such as bacteria and mold), easily leading to spoilage and deterioration of the medicinal liquid. Long-term storage may also cause stratification, precipitation, or crystallization, affecting the uniformity of administration. 3. Inconvenient to carry: High water content increases packaging volume, not only increasing transportation costs but also making the packaging more susceptible to damage during transport due to compression or collision.

[0003] Drug concentration and filling are core steps in pharmaceutical manufacturing, and their combined efficiency and control precision directly impact product quality, production efficiency, and compliance. However, in existing technologies, concentration and filling are often independent processes with fragmented control logic requiring manual intervention, potentially leading to the following problems: 1. After concentration, before filling, the volume data of the concentrated solution needs to be manually read and input into the filling equipment. Manual reading and input may introduce errors, potentially causing discrepancies in the actual filling volume between packages. 2. Relying entirely on manual adjustment and distribution for switching between equipment results in low production efficiency. Furthermore, human error can easily lead to problems with the final result; for example, failure to transfer the solution in time can cause continued evaporation in the concentration module, resulting in insufficient concentrated solution to meet the expected filling requirements. 3. The control of the distribution pump during the filling process is crude, mostly using fixed flow rate or time control, which cannot be adaptively adjusted according to the actual volume of the final liquid and the expected filling quantity, resulting in filling errors between the final formulation products. At the same time, when the equipment needs to switch to the production of different formulation products, the parameters of the distribution pump must be manually adjusted, which increases time costs and reduces production efficiency. Summary of the Invention

[0004] This invention overcomes the shortcomings of the prior art and provides a solution intelligent concentration and filling equipment with simple structure, reasonable design, higher production efficiency, stable filling accuracy, and controllable product quality.

[0005] To solve the above-mentioned technical problems, the technical solution of the present invention is as follows:

[0006] A smart solution concentration and filling device includes a control module, a concentration module, an extraction and distribution module, and a packaging module. The concentration module includes an evaporation assembly with an evaporator. The extraction and distribution module includes an extraction pump, a final liquid tank, and a distribution pump. The extraction pump is connected to the evaporator and the final liquid tank to extract the concentrated solution to the final liquid tank. The distribution pump is connected to the final liquid tank and works with the packaging module to deliver the solution in the final liquid tank to the packaging module for packaging. The final liquid tank is equipped with a final liquid measuring device to measure the solution volume. The control module is connected to the evaporation assembly, the extraction pump, the distribution pump, the final liquid measuring device, and the packaging module. After setting the solution filling quantity, the control module controls the distribution pump to distribute the solution evenly according to the filling quantity based on the solution volume feedback from the final liquid measuring device, and controls the packaging module to package the concentrated solution according to the quantity.

[0007] Furthermore, the final liquid tank is provided with a final liquid measurement space; the final liquid measurement space is vertically arranged, and its shape and inner diameter are consistent in all vertical directions; the final liquid tank is provided with a concentration inlet and a concentration outlet communicating with the final liquid measurement space, and a concentration inlet valve and a concentration outlet valve are respectively provided at the two, the extraction pump cooperates with the concentration inlet valve, and the concentration outlet valve cooperates with the distribution pump.

[0008] Furthermore, the evaporation assembly includes a heating tank with an internal heating space and a heating device disposed within the heating space; at least the bottom of the evaporation tank is located in the heating space, the evaporation tank is made of a thermally conductive material, and there is a gap between the outer wall of the portion of the evaporation tank located in the heating space and the inner wall of the heating tank; the heating tank is also provided with a heating inlet for filling the heating space with a thermally conductive medium, and the thermally conductive medium filling the heating space surrounds the portion of the evaporation tank located in the heating space and the heating device.

[0009] Furthermore, the evaporator is equipped with an evaporation space, and the heating space and the evaporation space are relatively sealed. The evaporator is equipped with a solution inlet, a solution outlet and a steam outlet that communicate with the evaporation space. The solution outlet is located at the lowest point of the evaporation space, and a solution outlet pipe is provided at the solution outlet. The solution outlet pipe passes through the heating space and protrudes from the heating tank, and cooperates with the extraction pump.

[0010] Furthermore, the concentration module includes a negative pressure generating component, which includes a vacuum pump; the vacuum pump cooperates with the steam outlet to extract gas in the evaporation space to form a negative pressure environment in the evaporation space; a solution inlet is provided at the solution inlet, and solenoid valves that control the conduction state of both the solution inlet and the solution outlet are provided at both the solution inlet and the solution outlet.

[0011] Furthermore, the concentration module also includes a condenser and a water collection tank; the condenser is connected to and communicates with the evaporator and the water collection tank; the vacuum pump is connected to and cooperates with the water collection tank, thereby drawing the steam generated by the evaporation component into the condenser, and then drawing the condensate formed by the steam in the condenser into the water collection tank.

[0012] Furthermore, it includes an inlet mechanism, which comprises an inlet valve body, an inlet pipeline, and an inlet device; the inlet pipeline cooperates with the inlet valve body and the solution inlet interface; a solenoid valve controlling the conduction state of the solution inlet interface is located at the inlet pipeline; the inlet device cooperates with the inlet pipeline to draw the solution from the inlet valve body and guide it to the evaporation space; the inlet device is connected to the control module and is controlled by it to operate.

[0013] Furthermore, it also includes a cleaning module, which includes a water supply device. The water supply device works with the final liquid tank and the inlet valve body to provide cleaning water to the inlet valve body and the final liquid measurement space. The water supply device is connected to and controlled by the control module to supply water. The inlet valve body is a three-way valve, which has a solution inlet channel, a cleaning liquid inlet channel, and a liquid outlet channel inside, and correspondingly has a solution inlet opening, a cleaning inlet opening, and a liquid outlet. The water supply device is connected to the cleaning inlet opening. The liquid outlet is connected to the inlet pipeline. The inlet valve body is equipped with a valve switch to control the opening and closing of the solution inlet channel, the cleaning liquid inlet channel, and the liquid outlet channel.

[0014] Furthermore, the evaporator includes a tank body and a cover detachably mounted on the tank body. The tank body has an internal space and an opening at the top. The cover closes to the opening of the tank body to form an evaporation space. The cover is located outside the heating space. A solution inlet and a solution addition interface are provided on the cover. The cleaning module also includes a rotary cleaning nozzle, which is mounted on the cover. When the cover is closed on the tank, the rotary cleaning nozzle is located within the evaporation space. The cover also has a cleaning interface that connects and cooperates with the rotary cleaning nozzle. The inlet pipeline includes a front-end pipeline and a rear-end branch pipeline. The inlet device uses a self-priming pump. The front-end pipeline connects to the liquid outlet and the suction inlet of the self-priming pump, ensuring communication between them. The rear-end branching pipeline includes an inlet pipe, a first branching pipe, and a second branching pipe, with the inlet pipe communicating with both the first and second branching pipes. The inlet pipe is connected to and communicates with the discharge outlet of the self-priming pump. The first branching pipe connects to and communicates with the solution inlet interface. A solenoid valve controlling the on / off state of the solution inlet interface is located on the first branching pipe. The second branching pipe connects to and communicates with the cleaning interface. A solenoid valve controlling the on / off state of the second branching pipe is also located on the second branching pipe. The rotating cleaning nozzle is connected to the control module and is controlled by it to perform rotating rinsing.

[0015] Furthermore, a foam sensor connected to the control module is installed on the tank body; at least the lower half of the tank body is in the heating space, and the foam sensor is installed in the position where the tank body is not in the heating space, with the sensing part of the foam sensor located in the evaporation space; the condenser tank and the water collection tank are connected by a water collection connecting pipe, and a vent valve that allows atmospheric pressure air to be introduced is also installed at the water collection connecting pipe.

[0016] Beneficial effects:

[0017] In this invention, the control module is directly connected to the evaporation assembly, extraction pump, distribution pump, final liquid measurement device, and packaging module, achieving a seamless connection between "concentration completion → automatic extraction → dynamic distribution → precise filling". Through the intelligent regulation of the control module, the real-time feedback of the final liquid measurement device, and the automated connection of the extraction and distribution module, the problems of low precision, poor efficiency, and high dependence on manual labor in traditional concentration and filling equipment are systematically solved. The invention realizes the integrated operation of "high-efficiency concentration, precise distribution, and intelligent filling", which significantly improves the production efficiency and product quality of pharmaceutical preparations.

[0018] In this invention, the final liquid measuring device can directly obtain the actual volume of the concentrated solution and then transmit the data to the control module in real time. The control module automatically calculates the amount of each preparation based on the set filling quantity and the real-time volume of the final liquid, and drives the dispensing pump to accurately deliver it to the packaging module. This avoids underfilling or overfilling as much as possible, thereby significantly reducing the filling error of a single package and improving the consistency of product dosage.

[0019] In this invention, other modules are managed by the same control module. When switching products, only the type and quantity of the new product need to be input into the control module. The system can automatically adjust parameters such as the working status of the evaporation component, the number of times the distribution pump works, the number of rotations of the distribution pump in a single operation, and the number of times the packaging module works, without the need for manual adjustment, thereby improving production efficiency. Furthermore, it can also support the rapid switching of formulations, improve equipment utilization, and thus adapt to the needs of multi-variety small-batch production.

[0020] In this invention, the final liquid measurement space of the final liquid tank is set vertically, and the shape and inner diameter of the final liquid measurement space are consistent in the vertical direction. This design ensures that the final concentrate is evenly distributed in the vertical final liquid measurement space, and the liquid level height and volume have a strict linear relationship. This significantly improves the accuracy of the final liquid volume data measurement and provides a reliable basis for the dynamic allocation logic of the control module.

[0021] Traditional concentration equipment often uses immersion heating, which can easily lead to excessively high local temperatures in the liquid, potentially damaging heat-sensitive components. In this invention, a heat-conducting medium is introduced into the heating space. After the heating device heats the medium, the heated medium transfers heat to the area surrounding the evaporator, thereby eliminating local temperature gradients and ensuring that the evaporator and the liquid inside are heated as evenly as possible.

[0022] Different medicinal solutions have different evaporation requirements; some require rapid evaporation of water, while others require slow concentration to retain volatile components. In this invention, the temperature can be increased by a heating device, or a suitable temperature-conducting medium can be added through a heated inlet, thereby adjusting the temperature of the heat-conducting medium within the heating space to meet the evaporation requirements of different medicinal solutions. This enhances the adaptability of the equipment, enabling it to process various medicinal solutions and meet different process requirements.

[0023] In this invention, there is a gap between the outer wall of the evaporator and the inner wall of the heating tank. This not only allows the heat-conducting medium to flow freely within the gap, improving the uniformity of heat conduction, but also avoids uneven heating of the evaporator that may occur due to the outer wall of the evaporator being in close contact with the inner wall of the heating tank, further eliminating heat dead zones. The medicine is heated evenly, which can effectively prevent heat-sensitive components from decomposing due to local high temperatures, and retain the alkaloids, polysaccharides and other active substances in the medicine to the greatest extent, thereby improving product quality.

[0024] In this invention, because the solution outlet is located at the lowest point of the evaporation space, gravity allows the concentrated solution to converge at the outlet. The concentrated solution is then transported to the final liquid tank via a solution outlet pipe and an extraction pump, reducing the residual amount in the evaporation space and minimizing concentrate loss. Simultaneously, since the solution outlet pipe passes through a heating tank to engage with the extraction pump, part of the outlet pipe itself is within the heating space. The temperature of the outlet pipe and the internal drug solution is maintained by the heat-conducting medium within the heating space. This helps prevent viscosity increases due to temperature drops during transfer. Increased drug viscosity can reduce flowability, decreasing transfer and filling efficiency, and may also lead to increased residual amount during transfer, resulting in insufficient dosage.

[0025] In this invention, a vacuum pump extracts gas from the evaporation space, creating a negative pressure environment that lowers the boiling point of the solution. The vapor generated during evaporation is also quickly extracted from the evaporation space, rapidly reducing moisture content and improving concentration efficiency. Under low temperature and negative pressure, the rate of moisture evaporation accelerates, shortening the concentration process time and increasing production efficiency. Simultaneously, heat-sensitive components (such as alkaloids and polysaccharides) decompose less due to the lower evaporation temperature, resulting in more stable product efficacy.

[0026] In this invention, the condenser is connected to and communicates with the evaporator and the water collection tank. A vacuum pump continuously draws in steam, causing it to quickly enter the condenser. This creates a stable negative pressure environment in the evaporation space, lowering the boiling point of the solution and accelerating evaporation. The steam generated from the evaporation of the solution may carry odors, microorganisms, or volatile organic compounds. The condenser condenses the steam into liquid, which is then collected into the water collection tank through a water collection connection pipe. This process collects both the steam and the condensate, preventing direct discharge that could pollute the production workshop.

[0027] In traditional equipment, the solution needs to be manually poured into the evaporator, which is time-consuming and prone to human error, such as inaccurate pouring or solution leakage, affecting the concentration effect. In this invention, through the setting and coordination of the inlet valve, inlet pipeline and inlet device, the control module issues corresponding instructions to automatically send the solution to be concentrated into the evaporator for concentration. This avoids solution overflow or insufficient volume caused by manual operation, and allows for more precise control of the amount of solution added, thereby ensuring the efficiency and quality of concentration.

[0028] In this invention, the water supply device, under the control of the control module, provides cleaning water to the inlet valve body and the final liquid measurement space, thereby achieving automated cleaning of the final liquid measurement space, the pipeline from the inlet valve body to the evaporation space, the evaporation space, and the pipeline from the evaporation space to the final liquid measurement space. The cleaning process requires no manual operation, is more efficient, and improves production efficiency. It also avoids mixing of different liquids when switching between different concentrated drug types, thus preventing interference with the final product. In this invention, the inlet valve body uses a three-way valve, allowing the cleaning fluid from the water supply device to clean all paths of the drug flow as needed, thus preventing mixing of different liquids.

[0029] In this invention, the lid of the evaporator is separable from the tank body. When cleaning or maintenance is required, the lid can be quickly opened to directly contact the inner wall of the evaporation space and thoroughly remove residue. A rotating cleaning nozzle is integrated on the lid. When the lid is closed, the nozzle is located within the evaporation space and is driven to rotate 360° by the control module, spraying cleaning fluid to cover the entire inner wall, thereby improving the cleaning effect and eliminating cleaning dead zones. This allows for rapid and high-quality cleaning when continuous operation is required, improving the equipment's working efficiency.

[0030] In this invention, the rear-end distribution pipeline includes an inlet pipe, a first distribution pipe, and a second distribution pipe, and both the first and second distribution pipes are equipped with solenoid valves to control their conduction state. This allows the solenoid valve on the second distribution pipe to be closed during solution introduction and initial cleaning, while only the solenoid valve on the first distribution pipe is opened, ensuring that the solution can be introduced into the evaporation space and that the path through which the solution flows can be cleaned. During further cleaning, the second distribution pipe is opened again to supply water to the rotating cleaning nozzle, which then performs further cleaning. This makes the cleaning work of this equipment more precise and of higher quality.

[0031] During the negative pressure evaporation process, the liquid medicine may produce foam due to excessively low air pressure, caused by surface-active substances (such as proteins and polysaccharides). This foam typically contains unevaporated active ingredients from the liquid medicine. Excessive foam can be drawn out of the evaporation space by the vacuum pump, resulting in liquid medicine loss, reduced product yield, and increased raw material costs. In this invention, a foam sensor is used. When foam exceeds a threshold, the opening and closing of the vent valve can be finely adjusted to introduce atmospheric air at normal pressure, maintaining a stable negative pressure environment within the system and thus eliminating foam. Simultaneously, this vent valve is located at the connection between the condenser and the water collection tank, away from the evaporation space, thereby minimizing the impact of ambient air entering the evaporation space after the vent valve is opened on the internal temperature of the evaporation space. Attached Figure Description

[0032] Figure 1 This is a structural diagram of the entire invention.

[0033] Figure 2 A structural diagram showing the inlet valve body and suction tube located on the inner surface of the housing.

[0034] Figure 3 This is a structural diagram of the valve body.

[0035] Figure 4 This is a cross-sectional view of the valve body.

[0036] Figure 5 This is a structural diagram of the present invention without a housing.

[0037] Figure 6 for Figure 5 The structural diagram of the other side.

[0038] Figure 7 This is a structural diagram of the condensation module.

[0039] Figure 8 This is a structural diagram of the evaporation assembly.

[0040] Figure 9 for Figure 8 Side view of the structure.

[0041] Figure 10 for Figure 8 Cross-sectional view.

[0042] Figure 11 This is a structural diagram of the cover.

[0043] Figure 12 This is a structural diagram of a condenser.

[0044] Figure 13 for Figure 12 Cross-sectional view.

[0045] Figure 14 This is a structural diagram of the water collection tank.

[0046] Figure 15 for Figure 14 Cross-sectional view.

[0047] Figure 16 This is a structural diagram of the junction between the back-end branch pipeline and the inlet device.

[0048] Figure 17 The structure diagram for extracting the allocation module.

[0049] Figure 18 This is a cross-sectional view of the final liquid tank.

[0050] Figure 19 This is a cross-sectional view of the final liquid tank from another direction.

[0051] Figure 20 This is a structural diagram of the packaging module.

[0052] Figure 21 Structural diagram of the guide sheet metal.

[0053] Figure 22 This is a structural diagram of the bag clamping mechanism.

[0054] Figure 23 This is a structural diagram of the transmission mechanism.

[0055] Figure 24 This is a structural diagram showing the assembly of the drive motor, fixed mounting block, and movable mounting block.

[0056] Figure 25 This is a structural diagram of the sealing and cutting mechanism.

[0057] Figure 26 This is a structural diagram of the cutting groove and cutting blade.

[0058] Numbering on the map:

[0059] 1. Control module; 2. Concentration module; 3. Extraction and distribution module; 4. Packaging module; 5. Evaporation assembly; 6. Negative pressure generating assembly; 7. Inlet mechanism; 8. Cleaning module; 9. Nitrogen generator; 10. Housing; 11. Control panel; 21. Condensate tank; 22. Water collection tank; 23. Water collection connection pipe; 24. Condensate connection pipe; 25. Vent valve; 31. Extraction pump; 32. Final liquid tank; 33. Distribution pump; 34. Final liquid measuring device; 41. Feeding mechanism; 42. Bag clamping mechanism; 43. Conveying mechanism; 44. Sealing and cutting mechanism; 45. Packaging mounting plate; 51. Evaporation tank; 52. Heating tank; 61. Vacuum pump; 71. Inlet valve body; 72. Rear end branch pipe; 73. Inlet device; 81. Water supply device; 82. Rotary cleaning nozzle; 100. Suction pipe; 101. Pressure sensor; 102. Temperature sensor; 103. Liquid level sensor; 104. Pressure gauge; 105. Foam sensor; 210. Condensation space; 211. Baffle; 212. First zone; 213. Second zone; 214. Third zone; 215. First condensation opening; 216. Second condensation opening; 217. Condensation pipe; 218. Condensation water inlet; 219. Condensation drain outlet; 221. Water collection space; 222. Water collection inlet; 223. Extraction connection port; 224. Drain outlet; 225. Drain interface; 226. Drain control valve; 227. Drain sensor; 321. Final liquid measurement space; 322. Concentrated liquid inlet; 323. 324. Concentrated liquid outlet; 325. Concentrated liquid inlet valve; 326. Concentrated liquid outlet valve; 327. Final liquid tank cleaning port; 328. Final liquid tank cleaning valve; 329. Final liquid tank drain outlet; 410. Final liquid tank drain valve; 411. Feeding wheel; 412. Guide sheet metal; 413. Guide inlet; 414. Guide outlet; 415. Consumables; 421. First drive cylinder; 422. Left clamping block; 423. Right clamping block; 424. First clamping block space; 431. Drive motor; 432. Fixed mounting block; 433. Movable mounting block; 434. Rotating shaft; 435. Driven gear; 436. Contact roller; 437. Drive gear; 438. Adjusting handle; 439. Connecting sheet metal; 441. Second drive cylinder; 442. Front clamp 443. Rear clamping block; 444. Second clamping block space; 445. Cutting groove; 446. Cutting blade; 447. Cutting cylinder; 451. Through notch; 511. Evaporation space; 512. Solution inlet; 513. Solution outlet; 514. Steam outlet; 515. Solution outlet pipe; 516. Solution inlet port; 517. Tank body; 518. Cover; 519. Cleaning port; 521. Heating space; 522. Heating device; 523. Heating inlet port; 524. Heating outlet port; 525. Heating pressure relief port; 526. Drain valve; 527. Inlet valve; 711. Solution inlet channel; 712. Cleaning fluid inlet channel; 713. Liquid outlet channel; 714. Solution inlet opening; 715.716. Cleaning inlet; 717. Liquid outlet; 721. Valve switch; 722. Inlet pipe; 723. First distributor pipe; 724. Second distributor pipe. Detailed Implementation

[0060] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. It should be noted that the embodiments are merely specific illustrations of the present invention, intended to enable those skilled in the art to better understand the technical solutions of the present invention, and should not be regarded as limitations on the present invention.

[0061] In the description of this invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this invention.

[0062] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0063] Example:

[0064] like Figure 1-26As shown, a solution intelligent concentration and filling device includes a control module 1, a concentration module 2, an extraction and distribution module 3, and a packaging module 4. The concentration module 2 includes an evaporation assembly 5 equipped with an evaporator 51. The extraction and distribution module 3 includes an extraction pump 31, a final liquid tank 32, and a distribution pump 33. The extraction pump 31 is connected to the evaporator 51 and the final liquid tank 32 to extract the concentrated solution to the final liquid tank 32. The distribution pump 33 is connected to the final liquid tank 32 and cooperates with the packaging module 4 to deliver the solution in the final liquid tank 32 to the packaging module 4 for packaging. The final liquid tank 32 is equipped with a final liquid measuring device 34 to measure the solution volume. The control module 1 is connected to the evaporation assembly 5, the extraction pump 31, the distribution pump 33, the final liquid measuring device 34, and the packaging module 4. After the operator sets the solution filling quantity in the control module 1, the control module 1 controls the distribution pump 33 to distribute the solution evenly according to the filling quantity based on the solution volume fed back by the final liquid measuring device 34, and then controls the packaging module 4 to package the concentrated solution according to the set quantity. In this invention, the control module 1 is directly connected to the evaporation assembly 5, the extraction pump 31, the distribution pump 33, the final liquid measuring device 34, and the packaging module 4, achieving seamless integration between "concentration completion → automatic extraction → dynamic distribution → precise filling". Through the intelligent regulation of the control module 1, the real-time feedback of the final liquid measuring device 34, and the automated connection of the extraction and distribution module 3, the problems of low precision, poor efficiency, and high reliance on manual labor in traditional concentration and filling equipment are systematically solved. The integrated operation of "high-efficiency concentration, precise distribution, and intelligent filling" of the equipment is realized, significantly improving the production efficiency and product quality of pharmaceutical preparations.

[0065] In this invention, the final liquid measuring device 34 can directly obtain the actual volume of the concentrated solution and then transmit the data to the control module 1 in real time. The control module 1 automatically calculates the amount of each preparation based on the set filling quantity and the real-time volume of the final liquid, and drives the dispensing pump 33 to accurately deliver it to the packaging module 4. This helps to avoid underfilling or overfilling as much as possible, thereby significantly reducing the filling error of a single package and improving the consistency of product dosage.

[0066] In this invention, other modules are managed by the same control module 1. When switching products, only the type and quantity of the new product need to be input into the control module 1. The system can automatically adjust parameters such as the working status of the evaporation component 5, the number of working times of the distribution pump 33, the number of rotations of the distribution pump 33 in a single operation, and the number of working times of the packaging module 4. No manual adjustment is required, thereby improving production efficiency. Furthermore, it can also support the rapid switching of formulations, improve equipment utilization, and thus adapt to the needs of multi-variety small-batch production.

[0067] In this invention, the final liquid tank 32 is provided with a final liquid measurement space 321. The final liquid measurement space 321 is vertically arranged, and its shape and inner diameter are consistent throughout the vertical direction. The final liquid tank 32 is provided with a concentration inlet 322 and a concentration outlet 323 communicating with the final liquid measurement space 321, and a concentration inlet valve 324 and a concentration outlet valve 325 are respectively provided at both. The extraction pump 31 cooperates with the concentration inlet valve 324, and the concentration outlet valve 325 cooperates with the distribution pump 33. The vertical arrangement of the final liquid measurement space 321 of the final liquid tank 32, and the design of the shape and inner diameter of the final liquid measurement space 321 being consistent in the vertical direction, ensures that the final concentrate is evenly distributed in the vertical final liquid measurement space 321, and the liquid level height has a strict linear relationship with the volume. This significantly improves the accuracy of the final liquid volume measurement data and provides a reliable basis for the dynamic allocation logic of the control module 1.

[0068] In this embodiment, the length direction of the sensing part of the final liquid measuring device 34 corresponds to the length direction of the final liquid measuring space 321, thereby enabling it to more accurately measure the volume of the final concentrate.

[0069] Traditional concentration equipment often uses immersion heating, which can easily lead to excessively high local temperatures in the liquid, potentially damaging heat-sensitive components. In this invention, the evaporation assembly 5 includes a heating tank 52 with an internal heating space 521 and a heating device 522 disposed within the heating space 521. At least the bottom of the evaporation tank 51 is located within the heating space 521. The evaporation tank 51 is made of a thermally conductive material, such as copper or stainless steel, which have good thermal conductivity. A gap exists between the outer wall of the portion of the evaporation tank 51 within the heating space 521 and the inner wall of the heating tank 52. The heating tank 52 is also provided with a heating inlet 523 for filling the heating space 521 with a heat-conducting medium. The heat-conducting medium filling the heating space 521 surrounds the portion of the evaporation tank 51 within the heating space 521 and the heating device 522. In this invention, a heat-conducting medium is introduced into the heating space 521. After the heat-conducting medium is heated by the heating device 522, it is then used to transfer heat to the evaporator 51, thereby eliminating local temperature gradients and ensuring that the evaporator 51 and the internal medicinal liquid are heated as evenly as possible. A gap exists between the outer wall of the evaporator 51 and the inner wall of the heating tank 52. This not only allows the heat-conducting medium to flow freely within the gap, improving heat conduction uniformity, but also prevents uneven heating of the evaporator 51 that might occur if the outer wall of the evaporator 51 is in close contact with the inner wall of the heating tank 52, further eliminating heat dead zones. Furthermore, the uniform heating of the medicinal liquid during evaporation and concentration effectively prevents the decomposition of heat-sensitive components due to localized high temperatures, maximizing the retention of active substances such as alkaloids and polysaccharides in the medicinal liquid and improving product quality.

[0070] Different medicinal solutions have different evaporation requirements; some require rapid evaporation of water, while others require slow concentration to retain volatile components. In this invention, the temperature can be increased by heating device 522, or a suitable temperature of heat-conducting medium can be added by heating inlet 523, thereby adjusting the temperature of the heat-conducting medium in heating space 521 to adapt to the evaporation requirements of different medicinal solutions. This enhances the adaptability of the equipment, enabling it to process various medicinal solutions and meet different process requirements.

[0071] In this embodiment, the heating tank 52 is also provided with a heating outlet 524 and a heating pressure relief port 525 communicating with the heating space 521. The heating pressure relief port 525 is located near the top of the heating tank 52 and the heating space 521. The heating pressure relief port 525 releases the pressure that rises synchronously in the heating space 521 due to temperature increase, thereby preventing the heating tank 52 from being damaged by overpressure. The heating outlet 524 allows some high-temperature heat transfer medium to be released when the temperature of the heating medium in the heating space 521 is too high, and then heat transfer medium of suitable temperature can be replenished through the heating inlet 523, thereby achieving reasonable temperature regulation of the heating medium in the heating space 521. At the same time, the heating outlet 524 also facilitates the release of the internal heating medium during transportation and handling of the equipment, making transportation and handling easier; moreover, the heating outlet 524 and the heating inlet 523 also allow operators to clean the heating space 521 regularly. A drain valve 526 is also provided at the heating outlet 524, allowing the operator to release the heat transfer medium in the heating space 521 by opening this valve. A water inlet valve 527 is provided at the heating inlet 523, allowing the operator to fill the heating space 521 with heat transfer medium by opening this valve. During operation, the liquid level of the heating medium in the heating space 521 is not higher than the location of the heating pressure relief port 525, thus achieving pressure relief in the heating space 521. Preferably, during operation, the liquid level of the concentrated medicine in the evaporation space 511 is lower than the liquid level of the heating medium in the heating space 521 to achieve better heat transfer.

[0072] In this embodiment, the heating device 522 uses a heating tube, and there is a certain gap between it and the part of the evaporator 51 that is in the heating space 521, thereby minimizing uneven heating of the evaporator 51. In this embodiment, the heating tank 52 is also equipped with a temperature sensor 102 for detecting the internal temperature of the heating space 521 and a liquid level sensor 103 for detecting the volume of the heat-conducting medium inside the heating space 521, and the two sensors are used to more accurately control the working status of the heating space 521.

[0073] In this invention, an evaporation space 511 is provided inside the evaporator 51, and the heating space 521 is relatively sealed to the evaporation space 511. The evaporator 51 is provided with a solution inlet 512, a solution outlet 513, and a steam outlet 514 communicating with the evaporation space 511. A solution outlet pipe 515 is provided at the solution outlet 513. The solution outlet pipe 515 passes through the heating space 521 and protrudes from the heating tank 52, and cooperates with the extraction pump 31. The solution outlet 513 is located at the lowest point of the evaporation space 511. Gravity allows the concentrated solution to converge at the solution outlet 513. Then, through the cooperation of the solution outlet pipe 515 and the extraction pump 31, the concentrated solution is sent to the final liquid tank 32, thereby reducing the residual amount in the evaporation space 511 and minimizing the loss of concentrated solution. Since the solution outlet tube 515 needs to pass through the heating tank 52 to cooperate with the extraction pump 31, part of the solution outlet tube 515 itself is located in the heating space 521. Therefore, the temperature of the solution outlet tube 515 and the internal drug solution can be maintained by the temperature of the heat-conducting medium in the heating space 521. This can prevent the viscosity of the solution from increasing due to the temperature drop during the transfer process to a certain extent. An increase in drug solution viscosity may not only reduce the fluidity, thus reducing the transfer and filling efficiency, but may also increase the residual amount during the transfer, resulting in insufficient filling volume of the formulation.

[0074] In this invention, the concentration module 2 includes a negative pressure generating component 6, which includes a vacuum pump 61. The vacuum pump 61 works in conjunction with the steam outlet 514 to extract gas from the evaporation space 511, creating a negative pressure environment within the evaporation space 511. A solution inlet 516 is provided at the solution inlet 512, and solenoid valves controlling the conduction state of both the solution inlet 516 and the solution outlet 515 are provided. The solenoid valves are connected to and controlled by the control module 1. By setting the solenoid valves, the solution inlet 512 and the solution outlet 513 can be sealed, which is beneficial for the device to extract gas from the evaporation space 511 through the vacuum pump 61, creating a negative pressure environment in the evaporation space 511, thereby reducing the boiling point of the solution in the evaporation space 511. The steam generated by evaporation can also be quickly extracted from the evaporation space 511 by the vacuum pump 61, rapidly reducing the moisture in the evaporation space 511 and improving the concentration efficiency. Under low temperature and negative pressure conditions, the rate of water evaporation is accelerated, the concentration process time is shortened, and production efficiency is improved. At the same time, heat-sensitive components (such as alkaloids and polysaccharides) decompose less due to the lower evaporation temperature, making the product's efficacy more stable.

[0075] In this invention, the concentration module 2 further includes a condenser tank 21 and a water collection tank 22. The condenser tank 21 is connected and communicates with the evaporator tank 51 and the water collection tank 22. The condenser tank 21 and the water collection tank 22 are connected and communicate with each other through a water collection connecting pipe 23, and the evaporator tank 51 and the condenser tank 21 are connected and communicate with each other through a condenser connecting pipe 24. A vacuum pump 61 is connected and cooperates with the water collection tank 22 to draw the steam generated by the evaporation component 5 into the condenser tank 21, and then draws the condensate formed by the steam in the condenser tank 21 into the water collection tank 22. The condenser tank 21 is connected and communicates with the evaporator tank 51 and the water collection tank 22. The vacuum pump 61 continuously draws in steam, allowing it to quickly enter the condenser tank 21. This creates a stable negative pressure environment in the evaporation space 511, lowering the boiling point of the solution and accelerating evaporation. The steam formed by the evaporation of the solution may carry odors, microorganisms, or volatile organic compounds. The condenser tank 21 condenses the steam into liquid and collects it into the water collection tank 22. This collects the steam and condensate, preventing direct discharge that could pollute the production workshop.

[0076] In this embodiment, the vacuum pump 61 is a water-circulating vacuum pump 61. Since the vacuum pump 61 needs to draw in steam, and the condenser 21 cannot guarantee that all the steam will be condensed into condensate, the non-water-circulating vacuum pump 61 may be damaged after drawing in steam; while the water-circulating vacuum pump 61 is less likely to cause this problem.

[0077] In this invention, an inlet mechanism 7 is included, comprising an inlet valve body 71, an inlet pipe, and an inlet device 73. The inlet pipe cooperates with the inlet valve body 71 and the solution addition interface 516. The inlet device 73 cooperates with the inlet pipe to draw the solution from the inlet valve body 71 and guide it to the evaporation space 511. The inlet device 73 is connected to and controlled by the control module 1. In traditional equipment, the solution needs to be manually poured into the evaporator 51, which is time-consuming and prone to human error, such as inaccurate pouring or solution leakage, affecting the concentration effect. In this invention, through the setting and cooperation of the inlet valve body 71, the inlet pipe, and the inlet device 73, the control module 1 issues corresponding instructions to automatically send the solution to be concentrated into the evaporator 51 for concentration. This avoids solution overflow or insufficient quantity caused by manual operation, and allows for more precise control of the amount of solution added, thereby ensuring the efficiency and quality of concentration.

[0078] In this invention, the solenoid valve controlling the conduction state of the solution inlet 516 is located at the inlet pipe. Since the solution inlet 516 needs to be connected to the inlet pipe, a certain amount of space is required for the connection operation. If the solenoid valve is installed at the solution inlet 516, it may affect the connection operation between the solution inlet 516 and the inlet pipe. The connection effect directly affects whether the concentrated drug solution can flow completely into the evaporation space 511. If the connection is not tight, the concentrated drug solution may leak, resulting in loss of potency and affecting the final product. However, after the solution inlet 516 is connected to the inlet pipe, controlling the conduction state of the inlet pipe is equivalent to controlling the conduction state of the solution inlet 516. Therefore, placing the solenoid valve at the inlet pipe minimizes interference and facilitates operation.

[0079] This invention also includes a cleaning module 8, which includes a water supply device 81. The water supply device 81 cooperates with the final liquid tank 32 and the inlet valve body 71, and provides cleaning water to the inlet valve body 71 and the final liquid measurement space 321. The water supply device 81 is connected to the control module 1 and is controlled by it to supply water. Under the control of the control module 1, the water supply device 81 provides cleaning water to the inlet valve body 71 and the final liquid measurement space 321, thereby realizing automated cleaning of the final liquid measurement space 321, the pipeline from the inlet valve body 71 to the evaporation space 511, the evaporation space 511, and the pipeline from the evaporation space 511 to the final liquid measurement space 321. The cleaning process does not require manual operation, is more efficient, and improves production efficiency. When the equipment switches to the type of concentrated medicine, it can also avoid mixing of different medicines, which would affect the output.

[0080] In this embodiment, the water supply device 81 is a water heater, which provides hot water for operation; compared with cold water, using hot water for equipment cleaning can achieve better cleaning results.

[0081] In this embodiment, the final liquid tank 32 is provided with a final liquid tank cleaning port 326 communicating with the final liquid measurement space 321, and a final liquid tank cleaning valve 327 is provided at the final liquid tank cleaning port 326. The water supply device 81 cooperates with the final liquid tank cleaning valve 327 to supply water. The final liquid tank cleaning port 326 is located near the top of the final liquid measurement space 321 to facilitate cleaning. The final liquid tank 32 is also provided with a final liquid tank drain port 328 communicating with the final liquid measurement space 321. The final liquid tank drain port 328 is located near the bottom of the final liquid measurement space 321, and the concentrated liquid outlet 323 is located at the lowest point of the final liquid measurement space 321. The height of the final liquid tank drain port 328 is higher than that of the concentrated liquid outlet 323. A final liquid tank drain valve 329 is provided at the final liquid tank drain port 328. Both the final liquid tank cleaning valve 327 and the final liquid tank drain valve 329 are connected to the control module 1. The inlet and outlet of the final liquid measurement space 321 are controlled by the control module 1, realizing automated cleaning of the final liquid tank 32. At the same time, the remaining cleaning water can be discharged through the concentrated liquid outlet 323, thereby cleaning the pipeline from the final liquid tank 32 to the packaging module 4.

[0082] In this embodiment, the inlet valve body 71 is a three-way valve, internally equipped with a solution inlet channel 711, a cleaning fluid inlet channel 712, and a liquid outlet channel 713, and correspondingly equipped with a solution inlet opening 714, a cleaning fluid inlet opening 715, and a liquid outlet 716. The water supply device 81 is connected to the cleaning fluid inlet opening 715; the liquid outlet 716 is connected to the inlet pipeline; and a valve switch 717 is provided on the inlet valve body 71 to control the opening and closing of the solution inlet channel 711, the cleaning fluid inlet channel 712, and the liquid outlet channel 713. The use of a three-way valve in the inlet valve body 71 allows the cleaning fluid from the water supply device 81 to clean all paths of the liquid flow as needed, thus preventing the mixing of different liquids.

[0083] In this invention, the evaporator 51 includes a tank body 517 and a cover 518 detachably mounted on the tank body 517. The tank body 517 has an internal space and an opening at the top. The cover 518 closes to the opening of the tank body 517 to form an evaporation space 511. The cover 518 is located outside the heating space 521. A solution inlet 512 and a solution addition interface 516 are provided on the cover 518. The cover 518 of the evaporator 51 is separable from the tank body 517. When cleaning or maintenance is required, the cover 518 can be quickly opened to directly contact the inner wall of the evaporation space 511 and thoroughly remove residues. The cleaning module 8 also includes a rotating cleaning nozzle 82, which is mounted on the cover 518. When the cover 518 is closed on the tank 517, the rotating cleaning nozzle 82 is located within the evaporation space 511. The cover 518 is also provided with a cleaning interface 519 that connects and cooperates with the rotating cleaning nozzle 82. The rotating cleaning nozzle 82 is connected to the control module 1 and is controlled by it to perform rotating rinsing. The rotating cleaning nozzle 82 is integrated on the cover 518. When the cover 518 is closed, the nozzle is located within the evaporation space 511 and is driven to rotate 360° by the control module 1, spraying cleaning liquid to cover the entire inner wall, thereby improving the cleaning effect and eliminating cleaning dead corners. This allows for rapid and high-quality cleaning when continuous operation is required, improving the working efficiency of the equipment.

[0084] In this embodiment, the inlet pipeline includes a front-end pipeline and a rear-end branch pipeline 72, and the inlet device 73 uses a self-priming pump. The front-end pipeline is connected to the liquid outlet 716 and the suction port of the self-priming pump, and the two are in communication. The rear-end branch pipeline 72 includes an inlet pipe 721, a first branch pipe 722, and a second branch pipe 723. The inlet pipe 721 is in communication with the first branch pipe 722 and the second branch pipe 723, respectively. The inlet pipe 721 is connected to and in communication with the discharge port of the self-priming pump. The first branch pipe 722 is in cooperation with and in communication with the solution addition interface 516. The second branch pipe 723 is in cooperation with and in communication with the cleaning interface 519. A solenoid valve is provided on the second branch pipe 723 to control its conduction state.

[0085] In this embodiment, the solenoid valve controlling the conduction state of the solution addition interface 516 is set on the first dispensing pipe 722, thereby providing convenience for the connection and cooperation between the first dispensing pipe 722 and the solution addition interface 516 without affecting the original function, and also making it easier to improve the tightness of the connection and cooperation between the two.

[0086] During solution introduction and initial cleaning, the solenoid valve on the second distributor pipe 723 is closed, and only the solenoid valve on the first distributor pipe 722 is opened to ensure that the solution can be introduced into the evaporation space 511 and that the path through which the solution flows can be cleaned. For further cleaning, the second distributor pipe 723 is opened again to supply water to the rotating cleaning nozzle 82, which then performs the cleaning. This makes the cleaning work of this equipment more precise and of higher quality.

[0087] In this embodiment, a housing 10 is also included, enclosing the other modules. The inlet valve body 71 is fixed to the inner surface of the housing 10, and the valve switch 717 of the inlet valve body 71 is located outside the housing 10, thus facilitating operator control of the valve switch 717. A suction tube 100 is also fixedly installed on the housing 10. One end of the suction tube 100 is inside the housing 10 and is connected to the solution inlet opening 714 of the inlet valve body 71 via a pipeline. The other end of the suction tube 100 is outside the housing 10, allowing the operator to connect a pipeline at this end to assist in drawing in the concentrated drug solution with a self-priming pump. The control panel 11 of the control module 1 protrudes from the housing 10, thus facilitating operator operation of the equipment and monitoring of its working status.

[0088] In this embodiment, the cover 518 is equipped with a pressure sensor 101, a temperature sensor 102, and a liquid level sensor 103. When the cover 518 is closed on the tank 517, the sensing parts of these three sensors are located within the evaporation space 511, and all three are connected to the control module 1. This allows for direct acquisition of real-time data on pressure, temperature, and liquid level in the evaporation space 511, facilitating operator monitoring and unified management and coordination by the control module 1. Furthermore, since the tank 517 and the cover 518 are detachable, after the cover 518 is removed, the operator can thoroughly clean the sensing parts of the pressure sensor 101, temperature sensor 102, and liquid level sensor 103.

[0089] In this embodiment, a pressure gauge 104 is also provided on the cover 518. The sensing part of the pressure gauge 104 is located inside the evaporation space 511, and the dial of the pressure gauge 104 is located outside the cover 518. The dial of the pressure gauge 104 is located outside the cover 518, which makes it convenient for the operator to observe the pressure value in real time.

[0090] In this invention, a foam sensor 105 connected to the control module 1 is also provided on the tank 517; at least the lower half of the tank 517 is in the heating space 521, and the foam sensor 105 is located in a position where the tank 517 is not in the heating space 521. The sensing part of the foam sensor 105 is located in the evaporation space 511; the condenser 21 and the water collection tank 22 are connected by a water collection connecting pipe 23, and a vent valve 25 for introducing atmospheric pressure air is also provided at the water collection connecting pipe 23. During the negative pressure evaporation process, the liquid medicine may produce foam due to the low air pressure caused by surface active substances (such as proteins and polysaccharides). The foam usually contains unevaporated effective components of the liquid medicine; when there is too much foam, it will be sucked out of the evaporation space 511 when the vacuum pump 61 is working, resulting in liquid medicine loss, reduced product yield, and increased raw material costs. In this invention, by setting up the foam sensor 105, when foam is detected to exceed the threshold, the opening and closing state of the vent valve 25 can be finely adjusted to introduce atmospheric air at normal pressure, maintain a stable negative pressure environment in the system, and thus eliminate foam. At the same time, the vent valve 25 is set at the connection between the condenser tank 21 and the water collection tank 22, in a position far away from the evaporation space 511, thereby minimizing the impact of the ambient temperature air entering the evaporation space 511 after the vent valve 25 is opened.

[0091] In this invention, a condenser tank 21 has a condensation space 210 inside; a partition 211 is provided in the condensation space 210 to divide it into a first region 212, a second region 213, and a third region 214; the first region 212 and the third region 214 are located at both ends of the condenser tank 21, and the second region 213 is located between the two, and the spaces are relatively sealed; the two ends of the condenser tank 21 are respectively provided with a first condensation opening 215 communicating with the first region 212 and a second condensation opening 216 communicating with the third region 214; the first condensation opening 215 is connected to and communicates with the evaporator tank 51, and the second condensation opening 216 is connected to and communicates with the water collection tank 22; the first condensation opening 215 is connected to the steam outlet 514 through a condensation connecting pipe 24, so that the first region 212 communicates with the evaporation space 511. A condenser pipe 217 is installed in the second region 213. Both ends of the condenser pipe 217 have openings that connect it to the first region 212 and the third region 214, and also connect the first region 212 and the third region 214. The condenser pipe 217 is relatively sealed to the second condensation space 210. The condenser tank 21 is also equipped with a condensate inlet 218 and a condensate drain outlet 219 that communicate with the second region 213. The interior of the condenser tank 21 is divided into the first region 212, the second region 213, and the third region 214 by a partition 211, thus forming a directional path for steam flow. When steam passes through the condenser pipe 217, it can fully exchange heat with the condensing medium in the second region 213, and then condense to form condensate water which finally enters the water collection tank 22. In this embodiment, the condensate inlet 218 is located at the bottom of the condenser tank 21, and the condensate drain outlet 219 is located at the top of the condenser tank 21. This ensures that when the condensing medium is injected into the second region 213, it overflows only after the second space is completely filled, thus allowing the steam in the condenser tube 217 to achieve a better heat exchange effect. Generally, water is used as the condensing medium in the second space. Simultaneously, since hot water has a lower density than cold water, the water surrounding the condenser tube 217 in the second region 213 will be heated after heat exchange with the steam in the condenser tube 217, and will gradually float to the surface of the cold water. The condensate drain outlet 219 at the top of the condenser tank 21 allows the higher-temperature water to overflow more effectively, maintaining a suitable liquid temperature in the second space to achieve a better condensation effect.

[0092] In this invention, a water collection tank 22 is located below a condenser tank 21. The water collection tank 22 contains a water collection space 221, and is equipped with a water collection inlet 222, an extraction connection port 223, and a drain outlet 224 that communicate with the water collection space 221. The water collection inlet 222 and the extraction connection port 223 are located at the top of the water collection tank 22, and the extraction connection port 223 is connected to a vacuum pump 61. This prevents the vacuum pump 61 from directly drawing condensate from the water collection space 221, thus avoiding the formation of negative pressure. The drain outlet 224 is located at the bottom of the water collection tank 22 and at the lowest point of the water collection space 221. A drain interface 225 is provided at the drain outlet 224, and a drain control valve 226 and a drain sensor 227 are installed at the drain interface 225 to detect whether there is water in the drain interface 225 and the water collection space 221. The water collection inlet 222 is connected to the second condensation opening 216 via the water collection connecting pipe 23, so that the water collection space 221 is connected to the third area 214. The water collection tank 22 is also equipped with a liquid level sensor 103 to prevent the vacuum pump 61 from failing to work properly due to excessive condensate collected in the water collection tank 22.

[0093] In this invention, the packaging module 4 includes a feeding mechanism 41, a bag clamping mechanism 42, a conveying mechanism 43, and a sealing and cutting mechanism 44. The feeding mechanism 41 includes a feeding wheel 411 for placing packaging consumables 415 and a guide sheet metal 412. The upper and lower ends of the guide sheet metal 412 are respectively provided with a guide inlet 413 and a guide outlet 414. The bag clamping mechanism 42 is located below the guide outlet 414. The consumables 415 pass through the guide sheet metal and bend to form a packaging bag shape. The bag clamping mechanism 42 seals the side of the consumables 415 along its length to initially form a packaging bag shape. The conveying mechanism 43 conveys the packaging bag with the side seal to the sealing and cutting mechanism 44 and performs bottom sealing and cutting of the packaging bag. Subsequently, after the dispensing pump 33 injects the concentrated medicine into the packaging bag through the unsealed top position, the conveying mechanism 43 continues to convey the medicine, and the sealing and cutting mechanism 44 completes the top sealing and cutting of the packaging bag, thereby completing the filling of the preparation. In traditional packaging processes, sealing, filling, and cutting are usually separate operations, requiring manual intervention or waiting for the previous step to complete. This design uses a conveyor mechanism 43 to connect these steps into a continuous process, thereby improving production efficiency. Simultaneously, the sealing and cutting mechanism 44, during its operation, completes both the top sealing of the previous bag of formulation and the bottom sealing of the next bag, further improving filling efficiency.

[0094] In this embodiment, the guide inlet 413 of the guide sheet metal is larger than the guide outlet 414, and the guide outlet 414 is annular, which is beneficial for the consumable 415 to pass through the guide sheet metal, bend and form a packaging bag shape for subsequent side sealing.

[0095] In this embodiment, the bag clamping mechanism 42 includes a first driving cylinder 421, a left clamping block 422, and a right clamping block 423. The first driving cylinder 421 drives the left clamping block 422 and the right clamping block 423 to move relative to each other and move closer together. Both the left clamping block 422 and the right clamping block 423 are made of thermally conductive materials, and each of them has a first clamping space 424. A heating element is provided in the first clamping space 424, and heat is conducted to the left clamping block 422 and the right clamping block 423 through the heating element. The left and right clamping blocks 423 and the first clamping spaces 424 provided inside them are all vertically arranged corresponding to the length direction of the formed packaging bag. The sealing and cutting mechanism 44 includes a second driving cylinder 441. A front clamping block 442 and a rear clamping block 443 are driven to move closer together by a second driving cylinder 441. Both the front clamping block 442 and the rear clamping block 443 are made of a thermally conductive material, and each has a second clamping space 444 within it. A heating element is installed in the second clamping space 444, and heat is conducted to the front clamping block 442 and the rear clamping block 443 through the heating element. The front and rear clamping blocks 443 and the second clamping spaces 444 within them are all horizontally arranged. A cutting groove 445 is also provided on the surface of the rear clamping block 443 facing the front clamping block 442, and a cutting blade 446 is installed within the cutting groove 445. The cutting groove 445 and the cutting blade 446 are horizontally arranged. The sealing and cutting mechanism 44 also includes a cutting cylinder 447 connected to and controlling the extension and retraction of the cutting blade 446. The left and right clamping blocks, as well as the front and rear clamping blocks, are all made of heat-conducting materials and have heating elements installed inside to support the bag clamping mechanism 42 and the sealing and cutting mechanism 44 in sealing the packaging bags. The cutting blade 446 is located in the cutting groove 445 when the front and rear clamping blocks are sealing. After the front and rear clamping blocks have completed the sealing, it performs the cutting function under the action of the cutting cylinder 447. When the heating element transfers heat to the rear clamping block 443, it simultaneously transfers heat to the cutting blade 446, making the cutting effect of the cutting blade 446 better.

[0096] It is worth noting that the cutting groove 445 can also be provided on the surface of the front clamping block 442 facing the rear clamping block 443, or the cutting groove 445 can be provided on the surfaces of the front and rear clamping blocks 443 facing each other; and the cutting blade 446 can be provided in the cutting groove 445.

[0097] In this invention, the packaging module 4 includes a vertically arranged packaging mounting plate 45, on which a bag clamping mechanism 42, a conveying mechanism 43, and a sealing and cutting mechanism 44 are mounted. The conveying mechanism 43 is located below the bag clamping mechanism 42, and the sealing and cutting mechanism 44 is located below the conveying mechanism 43. The conveying mechanism 43 delivers the packaging bag formed by the bag clamping mechanism 42 to the sealing and cutting mechanism 44. The conveying mechanism 43 includes a drive motor 431, a fixed mounting block 432, and a movable mounting block 433. The fixed mounting block 432 is fixed to the packaging mounting plate 45, and the movable mounting block 433 is movably mounted on the fixed mounting block 432 or the packaging mounting plate 45. Each component is equipped with a rotatable shaft 434, with a driven gear 435 and a contact roller 436 at each end of the shaft 434. The driven gears 435 and contact rollers 436 at both ends of the shaft 434 on the fixed mounting block 432 and the movable mounting block 433 are correspondingly arranged. A transmission motor 431 is mounted on the fixed mounting block 432, and a transmission gear 437 is provided on the motor shaft of the transmission motor 431. The transmission gear 437 meshes with the driven gear 435 of the shaft 434 on the fixed mounting block 432. The transmission mechanism 43 also includes an adjustment handle 438, which is connected to the movable mounting block 433 via a connecting sheet metal 439 to control the movement of the movable mounting block 433 and its shaft 434.

[0098] In this embodiment, the movable mounting block 433 is movably mounted on the fixed mounting block 432; the packaging mounting plate 45 is provided with a through notch 451 for the rotating shaft 434 on both the fixed mounting block 432 and the movable mounting block 433 to pass through; the fixed mounting block 432 is also provided with a through notch 451 for the rotating shaft 434 on the movable mounting block 433 to pass through; the through notch 451 of the rotating shaft 434 on the movable mounting block 433 corresponds to the movement path of the rotating shaft 434 on the movable mounting block 433. By controlling the adjusting handle 438, the position of the movable mounting block 433 can be changed, thereby adjusting the distance between the driven gear 435 and the contact roller 436 on the fixed mounting block 432 and the movable mounting block 433; this facilitates the replacement of the consumable 415 when it is exhausted.

[0099] In this invention, a nitrogen generator 9 connected to the control module 1 is also included; when the distribution pump 33 injects concentrated medicine into the packaging bag, nitrogen is simultaneously injected into the packaging bag through the pipeline; to avoid the drug components in the preparation from contacting oxygen and undergoing oxidation reaction as much as possible, while maintaining the stability of the medicine environment and preventing deterioration caused by oxidation or moisture as much as possible.

[0100] In this invention, a main valve for water supply to the equipment is also provided. The main valve is connected to a water source outside the equipment. At the same time, the main valve is connected to the water supply device 81, condensate water inlet 218, water circulation vacuum pump 61 and heating liquid inlet 523 of the equipment through pipelines, so as to realize the supply of water from the external water source to the equipment. Meanwhile, the final liquid tank drain valve 329 is also connected to a pipeline to transport the cleaning liquid discharged from the final liquid measurement space 321 through the final liquid tank drain outlet 328 to the outside of the equipment.

[0101] It is worth noting that when supplying water to the water supply device 81 and the heating space 521, the actual water storage capacity required by both and the stable temperature required by the heating space 521 need to be considered; when supplying water to the second zone 213, cold water needs to be continuously injected into the second zone 213 to achieve the condensation of hot steam.

[0102] The working process of this equipment includes a preparation stage, a pre-concentration cleaning stage, a concentration working stage, a packaging stage, and a post-concentration cleaning stage; when this equipment is working, the above stages are carried out in sequence.

[0103] The steps in the preparation phase are as follows:

[0104] (1) The operator connects the power supply, opens the main valve, and starts the equipment to power on the equipment and supplies water to the water supply device 81, the second area 213, the heating space 521, and the water circulation vacuum pump 61.

[0105] (2) The operator selects the type of drug to be concentrated and the quantity of packaging on the control panel 11.

[0106] The steps in the pre-concentration cleaning stage are as follows:

[0107] (1) The water supply device 81 supplies water to the inlet valve body 71 and the final liquid tank cleaning valve 327; the control module 1 controls the final liquid tank cleaning valve 327 to open, so that the cleaning liquid flows into the final liquid measurement space 321; the control module 1 controls or the operator manually controls the valve body switch 717 to control the cleaning liquid to flow to the solution inlet channel 711 or the liquid outlet channel 713.

[0108] (2) The control module 1 controls the self-priming pump to guide the cleaning liquid to the first distribution pipe 722 and / or the second distribution pipe 723; the control module 1 controls the solenoid valves at the first distribution pipe 722 and the second distribution pipe 723 to open; the first distribution pipe 722 guides the cleaning liquid to the solution inlet 512, which directly enters the evaporation space 511 for cleaning; the second distribution pipe 723 guides the cleaning liquid to the cleaning interface 519, and the evaporation space 511 is cleaned by rotating the cleaning nozzle 82.

[0109] (3) The cleaning liquid gathers at the lowest point of the evaporation space 511. The control module 1 controls the solenoid valve, extraction pump 31 and concentration inlet valve 324 at the solution outlet pipe 515 to open the solenoid valve and concentration inlet valve 324 at the solution outlet pipe 515. Then the extraction pump 31 sends the cleaning liquid to the final liquid measurement space 321.

[0110] (4) The control module 1 controls the final liquid tank drain valve 329 to open, thereby directly discharging the cleaning liquid into the final liquid measurement space 321 through the final liquid tank drain port 328; subsequently, the control module 1 controls the concentrated liquid outlet valve 325 to open and controls the distribution pump 33 to work, guiding the remaining cleaning liquid in the final liquid measurement space 321 to the packaging module 4, and cleaning the pipeline between the final liquid measurement space 321 and the packaging module 4.

[0111] (5) The control module 1 controls the packaging module 4 to package the cleaning liquid discharged by the distribution pump 33.

[0112] The steps in the condensation phase are as follows:

[0113] (1) The operator connects the pipe to one end of the suction tube 100 outside the shell 10 and puts the other end of the pipe into the liquid to be suctioned and concentrated.

[0114] (2) The control module 1 controls the self-priming pump and the solenoid valves at the first liquid distribution pipe 722 and the second liquid distribution pipe 723; after the solenoid valve at the first liquid distribution pipe 722 is opened and the solenoid valve at the second liquid distribution pipe 723 is closed, the self-priming pump works to draw the concentrated medicine into the evaporation space 511.

[0115] (3) The control module 1 controls the vacuum pump 61 and the heating device 522 to work. After a negative pressure is formed in the evaporation space 511, the liquid is evaporated and concentrated.

[0116] (4) After the drug solution is evaporated and concentrated, the control module 1 controls the solenoid valve, extraction pump 31 and concentration inlet valve 324 at the solution outlet pipe 515 to open the solenoid valve and concentration inlet valve 324 at the solution outlet pipe 515, and then the extraction pump 31 sends the concentrated liquid to the final liquid measurement space 321.

[0117] The steps in the packaging stage are as follows:

[0118] (1) The control module 1 controls the concentrated liquid outlet valve 325 to open, and then controls the distribution pump 33 to work according to the concentrated liquid volume fed back by the final liquid measuring device 34 and the preset packaging quantity, so as to guide the concentrated liquid to the packaging module 4.

[0119] (2) The control module 1 controls the packaging module 4 to work according to the preset packaging quantity.

[0120] The steps in the post-concentration cleaning stage correspond to the steps in the pre-concentration cleaning stage.

[0121] After each stage of the work is completed, the operator can shut off the water and power to the equipment according to the usage needs, and release the water in the heating space 521, the water collection tank 22, the second area 213 and the water supply device 81.

[0122] It is worth noting that, in this invention, the opening of valves such as solenoid valves, inlet valves, final liquid tank cleaning valves, and concentrate outlet valves refers to opening the valve body so that it or its set position is in a conductive state, enabling liquid flow; similarly, the closing of the aforementioned valve body refers to closing the valve body so that it or its set position is in a closed state.

[0123] It is worth noting that the other technical solutions of this invention are all prior art, and therefore will not be described in detail.

[0124] The above description is only a preferred embodiment of the present invention. It should be noted that those skilled in the art can make several improvements and modifications without departing from the concept of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A solution intelligent concentration and filling device, characterized in that, It includes a control module, a concentration module, an extraction and dispensing module, and a packaging module; The concentration module includes an evaporation assembly equipped with an evaporator; the extraction and distribution module includes an extraction pump, a final liquid tank, and a distribution pump; the extraction pump is connected to the evaporator and the final liquid tank to extract the concentrated solution to the final liquid tank; the distribution pump is connected to the final liquid tank and cooperates with the packaging module to deliver the solution in the final liquid tank to the packaging module for packaging. The final liquid tank is equipped with a final liquid measuring device to measure the volume of the solution; The control module is connected to the evaporation assembly, extraction pump, distribution pump, final liquid measuring device, and packaging module. After the control module sets the solution filling quantity, it controls the distribution pump to distribute the solution evenly according to the filling quantity based on the solution volume fed back by the final liquid measuring device, and controls the packaging module to package the concentrated solution according to the quantity.

2. The intelligent solution concentration and filling equipment according to claim 1, characterized in that, The final liquid tank is provided with a final liquid measurement space; the final liquid measurement space is vertically arranged, and its shape and inner diameter are consistent in all vertical directions; the final liquid tank is provided with a concentration inlet and a concentration outlet communicating with the final liquid measurement space, and a concentration inlet valve and a concentration outlet valve are respectively provided at the two; the extraction pump cooperates with the concentration inlet valve, and the concentration outlet valve cooperates with the distribution pump.

3. The intelligent solution concentration and filling equipment according to claim 2, characterized in that, The evaporation assembly includes a heating tank with an internal heating space and a heating device disposed within the heating space; at least the bottom of the evaporation tank is located in the heating space, and the evaporation tank is made of a thermally conductive material; the heating tank is also provided with a heating inlet for filling the heating space with a heat-conducting medium, and the heat-conducting medium surrounds the part of the evaporation tank located in the heating space and the heating device.

4. The intelligent solution concentration and filling equipment according to claim 3, characterized in that, The evaporator has an evaporation space inside, and the heating space and the evaporation space are relatively sealed. The evaporator is equipped with a solution inlet, a solution outlet and a steam outlet that communicate with the evaporation space. The solution outlet is located at the lowest point of the evaporation space, and a solution outlet pipe is provided at the solution outlet. The solution outlet pipe passes through the heating space and protrudes from the heating tank, and is used in conjunction with the extraction pump.

5. The intelligent solution concentration and filling equipment according to claim 4, characterized in that, The concentration module includes a negative pressure generating component, which includes a vacuum pump. The vacuum pump works in conjunction with the steam outlet to extract gas from the evaporation space and create a negative pressure environment in the evaporation space. A solution inlet is provided at the solution inlet, and solenoid valves are provided at both the solution inlet and the solution outlet to control their conduction state.

6. The intelligent solution concentration and filling equipment according to claim 5, characterized in that, The concentration module also includes a condenser and a water collection tank; the condenser is connected to and communicates with the evaporator and the water collection tank; the vacuum pump is connected to the water collection tank to draw the steam generated by the evaporation component into the condenser, and then draw the condensate formed by the steam in the condenser into the water collection tank.

7. The intelligent solution concentration and filling equipment according to claim 6, characterized in that, It includes an inlet mechanism, which comprises an inlet valve body, an inlet pipeline, and an inlet device; the inlet pipeline cooperates with the inlet valve body and the solution inlet interface; a solenoid valve controlling the conduction state of the solution inlet interface is located at the inlet pipeline; the inlet device cooperates with the inlet pipeline to draw the solution from the inlet valve body and guide it to the evaporation space; the inlet device is connected to the control module and is controlled by it to operate.

8. The intelligent solution concentration and filling equipment according to claim 7, characterized in that, It also includes a cleaning module, which includes a water supply device; the water supply device works with the final liquid tank and the inlet valve body, and provides cleaning water to the inlet valve body and the final liquid measurement space; the water supply device is connected to the control module and is controlled by it to supply water. The inlet valve body is a three-way valve, which has a solution inlet channel, a cleaning fluid inlet channel and a liquid outlet channel inside, and correspondingly has a solution inlet opening, a cleaning inlet opening and a liquid outlet; the water supply device is connected to the cleaning inlet opening; the liquid outlet is connected to the inlet pipeline; the inlet valve body is equipped with a valve body switch to control the opening and closing of the solution inlet channel, the cleaning fluid inlet channel and the liquid outlet channel.

9. The intelligent solution concentration and filling equipment according to claim 8, characterized in that, The evaporator includes a tank body and a cover that can be detachably mounted on the tank body. The tank body has an internal space and an opening at the top. The cover closes to the opening of the tank body to form an evaporation space. The cover is located outside the heating space; The cleaning module also includes a rotary cleaning nozzle, which is mounted on the cover. When the cover is closed on the tank, the rotary cleaning nozzle is located in the evaporation space. The cover is also provided with a cleaning interface that connects and cooperates with the rotary cleaning nozzle. The inlet pipeline includes a front-end pipeline and a rear-end branch pipeline, and the inlet device uses a self-priming pump. The front-end pipeline is connected to the liquid outlet and the suction inlet of the self-priming pump, and the two are in communication. The rear-end branch pipeline includes an inlet pipe, a first branch pipe, and a second branch pipe, with the inlet pipe communicating with both the first and second branch pipes. The inlet pipe is connected to the discharge outlet of the self-priming pump, and the first branch pipe is connected to the solution inlet interface. A solenoid valve controlling the on / off state of the solution inlet interface is installed on the first branch pipe. The second branch pipe is connected to the cleaning interface and is equipped with a solenoid valve controlling its on / off state. The rotating cleaning nozzle is connected to the control module and is controlled by it to perform rotating rinsing.

10. A solution intelligent concentration and filling device according to claim 9, characterized in that, The tank is also equipped with a foam sensor connected to the control module; at least the lower half of the tank is in the heating space, the foam sensor is located in a position where the tank is not in the heating space, and the sensing part of the foam sensor is located in the evaporation space. The condenser and the water collection tank are connected by a water collection connection pipe, and a vent valve that allows atmospheric pressure air to enter is also installed at the water collection connection pipe.

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