Compound antibacterial nail cream containing hanfengji cream and binding therapy of compound antibacterial nail cream containing hanfengji cream

Abstract

The invention discloses a compound antibacterial nail cream containing hanghai cream and a binding therapy thereof, and relates to the technical field of dermatological external preparations, the compound antibacterial nail cream comprises active components and a matrix, the active components comprise, by weight, 10%-20% of hanghai powder, 5%-10% of salicylic acid, 5%-10% of benzoic acid, 5%-10% of boric acid, 10%-20% of talcum powder and 5%-8% of carbamide, and the matrix is prepared from, by weight, 20%-30% of water. Components with different effects are combined, and salicylic acid, benzoic acid and carbamide cooperate to jointly achieve the effects of softening and exfoliating sick nail cutin; and meanwhile, through the mutual cooperation of the buddleja officinalis powder, the boric acid and the components, the growth of microorganisms can be inhibited. In addition, the base material formed by the vaseline and the liquid paraffin can enable the ointment body to keep a proper ointment form, and is convenient to smear and attach. The application method comprises the following steps of: grinding a diseased nail, applying the ointment and binding, so that the active ingredients can be promoted to permeate into a nail bed.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of dermatological external preparations, in particular to a compound antibacterial nail cream containing Hanzhi cream and a bandaging therapy. BACKGROUND

[0002] Nail cream is a kind of external preparation that directly acts on the nail and its surrounding skin, usually in the form of cream or ointment. Its core function is to achieve the purpose of treating nail diseases (such as onychomycosis and paronychia), caring for nails, or improving the appearance of nails through the active ingredients it contains.

[0003] Currently, the active ingredients of commercially available external products for treating gray nails are mostly single antifungal drugs (such as amorolfine) or chemical keratolytic agents (such as high-concentration urea). However, due to the dense and hard physical barrier of the nail itself, it is difficult for single-component ointments to effectively penetrate into the deep layer of the nail plate and the nail bed, resulting in slow onset, long treatment period, and uncertain efficacy.

[0004] In view of the above deficiencies of the prior art, an external nail cream preparation and therapy that can more effectively soften, penetrate, and remove diseased nails, while also having antimicrobial effects, and significantly improving efficacy through a specific bandaging method, is designed to achieve the synergistic compounding of traditional Chinese medicine extracts and modern chemical drugs, and to provide a feasible solution for realizing this technical problem by combining with the closed bandaging technology. SUMMARY

[0005] In view of the deficiencies of the prior art, the present application provides a compound antibacterial nail cream containing Hanzhi cream and a bandaging therapy, which solves the technical problems raised in the background art.

[0006] To achieve the above purpose, the present application is implemented by the following technical scheme: a compound antibacterial nail cream containing Hanzhi cream, which is composed of active ingredients and a base, and the composition is as follows in terms of total weight percentage: active ingredients: good Hanzhi powder: 10%~20%, salicylic acid: 5%~10%, benzoic acid: 5%~10%, boric acid: 5%~10%, talc: 10%~20%, carbamide: 5%~8%; base: vaseline: 15%~25%, liquid paraffin: 3%~5%; the weight ratio of the active ingredients to the base is (4.0~6.0):(1.8~3.0).

[0007] Preferably, the good Hanzhi powder is a powder of dried roots of good Hanzhi, with a fineness of 80 to 200 mesh.

[0008] Preferably, the method comprises the following steps: (1) raw material preparation: weighing the raw materials according to the proportions described in claim 1; (2) mixing: putting the raw materials into a dry-wet mixer and mixing them to obtain a uniform mixture of active ingredients; (3) paste preparation: adding vaseline and liquid paraffin to the mixture of active ingredients obtained in step (2), and mixing them until a uniform paste is formed; (4) packaging: packaging the paste obtained in step (3) according to predetermined specifications.

[0009] Preferably, the method comprises the following steps: (a) nail treatment: using a nail treatment tool to grind off the surface layer and thickened part of the diseased nail until the nail becomes thin and most of the nail bed is exposed; (b) cleaning and lubricating: using a cotton ball dipped in aviation kerosene or liquid paraffin to wipe the treated nail and surrounding skin to clean, cool and lubricate; (c) applying the medicine and bandaging: taking an appropriate amount of the compound antibacterial nail paste according to claim 1 or 2, and evenly applying it to the surface of the treated nail, with the amount being sufficient to completely cover the nail without overflowing; then using an elastic band-aid or medical tape to seal and bandage the treated nail; (d) continuous bandaging: continuously bandaging the nail for 46-55 hours; (e) removing and cleaning: after the bandaging time, remove the bandage and gently clean the remaining paste with water, avoiding the use of alkaline cleaners; (f) repeating the treatment: repeat the bandaging process of steps (a) to (e) with a 46-55 hour bandaging interval and a 1-2 hour rest interval, and perform continuous bandaging for 4 times 8 days as a course of treatment. If the nail is particularly severe, observe for one week to one month, and if necessary, supplement the bandaging according to the same operation. Generally, the diseased nail can recover after one or two courses of treatment.

[0010] Preferably, the elastic band-aid in step (c) is a Yunnan White Drug elastic band-aid.

[0011] Advantages The application provides a compound antibacterial nail cream containing Hanzhi paste and a bandaging therapy thereof. Different components with different effects are combined in the application. Salicylic acid, benzoic acid and carbamide are synergized to soften and exfoliate the keratin of diseased nails. Meanwhile, good Hanzhi powder, boric acid and the above components are mutually matched to help inhibit the growth of microorganisms. In addition, the base formed by vaseline and liquid paraffin can keep the cream in a proper ointment form, facilitating the application and adhesion. In the use method, the process of first grinding the diseased nails and then applying the cream and bandaging can promote the penetration of active ingredients into the nail plate and nail bed. After the therapy is applied, the physical replacement process in which the diseased nails are gradually replaced by new nails can be observed, and the user is provided with clear operation instructions, thereby helping to alleviate the troubles caused by onychomycosis. BRIEF DESCRIPTION OF DRAWINGS

[0012] Figure 1 A flowchart schematic diagram of the compound antibacterial nail cream containing Hanzhi paste and the bandaging therapy thereof is shown in the application. DETAILED DESCRIPTION

[0013] The technical solutions in the embodiments of the application will be clearly and completely described in combination with the drawings in the embodiments of the application. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments. Based on the embodiments in the application, all other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the application.

[0014] Please refer to Figure 1 The application provides a technical solution: a compound antibacterial nail cream containing Hanzhi paste, which is composed of active ingredients and a base, and the composition is as follows according to the total weight percentage: active ingredients: good Hanzhi powder: 10% to 20%, salicylic acid: 5% to 10%, benzoic acid: 5% to 10%, boric acid: 5% to 10%, talc: 10% to 20%, carbamide: 5% to 8%; base: vaseline: 15% to 25%, liquid paraffin: 3% to 5%; the weight ratio of the active ingredients to the base is (4.0~6.0):(1.8~3.0).

[0015] In this embodiment, the good Hanzhi powder is the powder of dried roots of good Hanzhi, and the fineness is 80 to 200 meshes.

[0016] The embodiment is further provided with the following steps: (1) raw material preparation: weighing the proportions of the hohan branch powder, salicylic acid, benzoic acid, boric acid, talc, carbamide, vaseline and liquid paraffin according to the proportions in claim 1; (2) mixing: putting the hohan branch powder, salicylic acid, benzoic acid, boric acid, talc and carbamide weighed in step (1) into a dry and wet mixer, and mixing by dry method to obtain a uniform active ingredient powder mixture; (3) paste preparation: adding the weighed vaseline and liquid paraffin into the active ingredient powder mixture obtained in step (2), and starting the wet mixing function of the mixer to fully stir and shear until a uniform paste is formed; (4) packaging: packaging the paste prepared in step (3) according to the predetermined specifications.

[0017] The embodiment is further provided with the following steps: (a) nail grinding: using a nail grinding tool to grind off the surface layer and thickened part of the diseased nail until the diseased nail is thinned and most of the nail bed is exposed; (b) cleaning and lubricating: using a cotton ball dipped in aviation kerosene or liquid paraffin to wipe the diseased nail and the surrounding skin after grinding, to clean, cool and lubricate; (c) applying medicine and bandaging: taking an appropriate amount of the compound antibacterial nail paste according to claim 1 or 2, and uniformly applying it to the surface of the ground diseased nail, with the amount being sufficient to completely cover the diseased nail without overflowing; then using an elastic band-aid or medical tape to seal and bandage the medicated nail; (d) continuous bandaging: continuously bandaging the diseased nail for 46-55 hours; (e) removing and cleaning: after the bandaging time, remove the bandage and gently clean the remaining medicine paste with clean water, avoiding the use of alkaline cleaners; (f) repeated treatment: repeat the bandaging process of steps (a) to (e) with a continuous bandaging of 46-55 hours each time, with a 1 to 2 hour rest interval, for a total of 4 times, 8 days as a course of treatment. If the diseased nail is particularly severe, it needs to be observed for one week to one month, and the same operation is performed for the supplementary bandaging. Generally, the diseased nail can recover after one or two courses of treatment.

[0018] The embodiment is further provided with the following steps: (a) nail grinding: using a nail grinding tool to grind off the surface layer and thickened part of the diseased nail until the diseased nail is thinned and most of the nail bed is exposed; (b) cleaning and lubricating: using a cotton ball dipped in aviation kerosene or liquid paraffin to wipe the diseased nail and the surrounding skin after grinding, to clean, cool and lubricate; (c) applying medicine and bandaging: taking an appropriate amount of the compound antibacterial nail paste according to claim 1 or 2, and uniformly applying it to the surface of the ground diseased nail, with the amount being sufficient to completely cover the diseased nail without overflowing; then using an elastic band-aid or medical tape to seal and bandage the medicated nail; (d) continuous bandaging: continuously bandaging the diseased nail for 46-55 hours; (e) removing and cleaning: after the bandaging time, remove the bandage and gently clean the remaining medicine paste with clean water, avoiding the use of alkaline cleaners; (f) repeated treatment: repeat the bandaging process of steps (a) to (e) with a continuous bandaging of 46-55 hours each time, with a 1 to 2 hour rest interval, for a total of 4 times, 8 days as a course of treatment. If the diseased nail is particularly severe, it needs to be observed for one week to one month, and the same operation is performed for the supplementary bandaging. Generally, the diseased nail can recover after one or two courses of treatment.

[0019] The detailed connection means is a technology known in the art, and the working principle and process are described below. The specific work is as follows.

[0020] Example: Preparation of nail paste First, accurately weigh each raw material according to the following specific weight ratio: 40 grams of Hao Han branch powder (fineness of 150 mesh), 20 grams of salicylic acid, 20 grams of benzoic acid, 20 grams of boric acid, 40 grams of talc, 25 grams of carbamide, 50 grams of vaseline, and 10 grams of liquid paraffin. The preparation process is carried out in a clean environment. First, put the weighed Hao Han branch powder, salicylic acid, benzoic acid, boric acid, talc, and carbamide into the container of the dry-wet mixer, and mix them for 15 minutes at a speed of 60 revolutions per minute until a uniformly colored mixed powder is obtained. Then, add the weighed vaseline and liquid paraffin to the mixed powder, switch to the wet mixing and shearing mode of the mixer, and stir for 20 minutes at a speed of 30 revolutions per minute. Finally, a light brown paste with uniform texture and moderate viscosity is obtained. The prepared paste is divided into 20-gram plastic boxes and sealed for storage.

[0021] Application of bandaging therapy A patient diagnosed with severe onychomycosis (gray nails) was selected, whose toenails on both feet were significantly thickened, turbid, and brittle, with white patches on the surface of the nail plate. The treatment process was as follows: First, use an electric nail grinder with a grinding head to grind the nails, focusing on removing the thick and brittle nail material until the nail plate is thinned and the underlying solid nail bed structure is exposed. At this time, some turbid areas can still be seen on the surface of the nail plate. During the grinding process, heat is generated due to the friction between the grinding head and the nail, so a cotton ball dipped in aviation kerosene is used to wipe the ground area to cool and clean the debris. After grinding is completed, about 2 grams of nail paste prepared in this example is evenly applied to the entire surface of the ground nail with a spatula, with a thickness of about 1-2 millimeters, completely covering the nail but not overflowing to the surrounding skin. Then, use a piece of Yunnan Baiyao elastic bandage to tightly bandage the medicated toe nail, ensuring that the paste is in close contact with the nail surface and is well sealed. The bandage is removed after 48 hours and the remaining paste is gently wiped off with a soft cloth soaked in warm water. During this period, no alkaline products such as soap or shower gel are used to clean the affected area.

[0022] After the first bandage was removed, a slight whitening and desquamation of the skin around the nail was observed. The treatment was repeated every 46-55 hours, with 2 hours interval (to allow the skin to breathe), following the method described above. After four cycles of treatment (total of eight days), the patient observed that the turbid part of the nail surface started to lift in patches, and the dead keratin layer (nail) could be easily peeled off using a blunt knife. Beneath the peeled-off layer, a new nail plate was visible, which was significantly smoother and closer to the color of a healthy nail. In the following 7-30 days, the new nail plate was observed to continuously grow forward from the nail root, and the original nail area was gradually replaced by the new nail plate. The hardness and luster of the nail were also improved. During the whole treatment, the patient only felt a short-term pain after the first application of the ointment, and no other discomfort was observed. This example directly demonstrates the process of the present therapy, which removes the diseased nail and promotes the regeneration of a new nail through the combination of chemical softening, antibacterial effect, and physical exfoliation in stages.

[0023] It should be noted that the relational terms herein such as first and second and the like are used solely to distinguish one entity or action from another, without necessarily requiring or implying any such actual relationship or order between such entities or actions.

Claims

1. A compound antibacterial nail cream containing *Houttuynia cordata* extract, characterized in that, Composed of active ingredients and matrix, its composition by total weight percentage is as follows: Active ingredients: Heroic branch powder: 10%~20%, salicylic acid: 5%~10%, benzoic acid: 5%~10%, boric acid: 5%~10%, talc: 10%~20%, carbamide: 5%~8%; Matrix: petrolatum: 15%~25%, liquid paraffin: 3%~5%; The weight ratio of the active ingredients to the matrix is ​​(4.0~6.0):(1.8~3.0).

2. The compound antibacterial nail cream containing *Houttuynia cordata* extract according to claim 1, characterized in that, The powder of the "Hero's Branch" is the powder of the dried roots of the "Hero's Branch," with a fineness of 80 to 200 mesh.

3. The processing method of a compound antibacterial nail cream containing *Houttuynia cordata* extract according to claim 1, characterized in that, Includes the following steps: (1) Raw material preparation: Weigh out the proportions of eucommia ulmoides powder, salicylic acid, benzoic acid, boric acid, talc, carbamide, petrolatum and liquid paraffin as described in claim 1 respectively; (2) Mixing: Put the eucommia ulmoides powder, salicylic acid, benzoic acid, boric acid, talc and carbamide weighed in step (1) into a dry and wet mixer and dry mix them to obtain a uniform active ingredient powder mixture; (3) Paste preparation: Add the weighed petrolatum and liquid paraffin to the active ingredient powder mixture obtained in step (2), start the wet mixing function of the mixer, and stir and shear thoroughly until a uniform paste is formed; (4) Packaging: Package the paste obtained in step (3) according to the predetermined specifications.

4. The bandaging therapy of a compound antibacterial nail cream containing *Houttuynia cordata* ointment according to claim 1, characterized in that, The procedure includes the following steps: (a) Nail trimming: Using nail trimming tools, the surface layer and thickened portion of the diseased nail are trimmed until the nail is thinned, exposing most of the nail bed; (b) Cleaning and lubrication: Using cotton balls soaked in aviation kerosene or liquid paraffin, the trimmed nail and surrounding skin are wiped to clean, cool, and lubricate; (c) Medication application and bandaging: An appropriate amount of the compound antibacterial nail cream described in claim 1 or 2 is applied evenly to the surface of the trimmed nail, with the amount sufficient to completely cover the nail without overflowing; then, an elastic bandage or medical tape is used to seal the nail after the medication is applied. (d) Continuous bandaging: Bandage the affected nail continuously for 46-55 hours; (e) Removal and cleaning: After the bandaging time is up, remove the bandage and gently clean away any residual ointment with clean water. Avoid using alkaline cleaners; (f) Repeat treatment: Repeat the bandaging process from (a) to (e), bandaging continuously for 46-55 hours each time, with a rest interval of 1 to 2 hours, for a total of 4 times over 8 days as one course of treatment. If the affected nail is particularly severe, observe for one week to one month. If re-bandaging is needed, follow the same procedure as before. Generally, the affected nail can recover in one or two courses of treatment.

5. The bandaging therapy of a compound antibacterial nail cream containing *Houttuynia cordata* ointment according to claim 4, characterized in that, The elastic bandage mentioned in step (c) is Yunnan Baiyao elastic bandage.

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