Composition for comprehensive conditioning of internal environment and preparation method thereof

Abstract

The invention discloses a composition for comprehensive conditioning of an internal environment, which comprises the following components in parts by weight: 1000-1200 parts of alpha-linolenic acid, 100-300 parts of cordyceps militaris powder, 50-150 parts of oyster powder, 50-150 parts of ginseng powder, 50-150 parts of pueraria peptide, 50-150 parts of fresh lalang grass rhizome powder and 50-150 parts of polygonatum odoratum powder. Wherein the purity of the alpha-linolenic acid is not lower than 80%. According to the invention, high-purity alpha-linolenic acid and six specific medicinal and edible components are scientifically proportioned to construct a multi-level synergistic system, and all the components complement and synergism on a plurality of targets such as lipid lowering, circulation promoting, sugar stabilizing, acid discharging, repairing and the like, so that comprehensive conditioning on disorder of multiple indexes such as blood fat, blood sugar, uric acid, blood pressure and the like is realized; the limitation of a single component or a simple compound product is broken through, and the comprehensive synergistic conditioning of the internal environment is realized; all the components are selected from a medicinal and edible substance catalog, so that the traditional Chinese medicine composition is safe and mild, meets the physique requirements of Chinese people on warm nourishing and conditioning, gives consideration to conditioning and repairing, and is high in adaptability.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of functional food or health food, in particular to a composition for comprehensive regulation of internal environment and a preparation method thereof. BACKGROUND

[0002] With the change of lifestyle, sub-health and chronic problems caused by metabolic abnormalities are becoming increasingly common. Linolenic acid, especially alpha-linolenic acid (ALA), as an essential omega-3 polyunsaturated fatty acid for the human body, has been proven to have physiological functions such as regulating blood lipids, anti-inflammatory, and improving insulin sensitivity. Therefore, there are various foods or health foods on the market that highlight the supplementation of linolenic acid.

[0003] However, such products in the prior art still have obvious defects: (1) Most products are single linolenic acid supplements, or only simple superposition of a few ingredients, lacking systematic design based on human metabolic pathways. The ingredients cannot form a system of mutual complementation and synergistic effect, resulting in single target regulation, and it is difficult to achieve comprehensive and stable regulation effect for complex internal environment disorders such as multiple indicators of blood glucose, blood lipids, and uric acid. Poor formulation synergy; (2) Existing products focus on "index regulation", and the formula design often ignores the basic nutritional support and repair of cells (such as mitochondria, nerve cells), and the improvement of overall immune function. In addition, the universal formula does not fully consider the physical characteristics and dietary habits of the Chinese population, and some products contain artificial synthesis or non-traditional food ingredients, ignoring basic repair and physical adaptation, and the safety and adaptability of long-term use are questionable; (3) Many products have broad claims of efficacy, lack specific and quantifiable effect data support, and cannot allow consumers to establish a clear expectation of "perceptible and detectable", resulting in insufficient market credibility.

[0004] Therefore, it is necessary to provide a composition for comprehensive regulation of internal environment and a preparation method thereof to overcome the above-mentioned defects. SUMMARY

[0005] The purpose of the present application is to provide a composition for comprehensive regulation of internal environment and a preparation method thereof, which aims to solve the technical problem that existing linolenic acid products cannot comprehensively and systematically regulate the internal environment due to single formula and poor synergy.

[0006] In order to achieve the above object, the present application provides a composition for comprehensive regulation of internal environment, comprising the following components in parts by weight: 1000-1200 parts of alpha-linolenic acid, 100-300 parts of cordyceps militaris powder, 50-150 parts of oyster powder, 50-150 parts of ginseng powder, 50-150 parts of pueraria peptide, 50-150 parts of fresh Imperata cylindrical root powder, and 50-150 parts of polygonatum sibiricum powder; wherein the purity of the alpha-linolenic acid is not less than 80%.

[0007] In a preferred embodiment, the alpha-linolenic acid is obtained by low-temperature cold extraction of perilla seed oil.

[0008] In a preferred embodiment, the purity of the alpha-linolenic acid is 81%.

[0009] In a preferred embodiment, the weight of the cordyceps militaris powder is 200 parts.

[0010] In a preferred embodiment, the weight of the oyster powder, the ginseng powder, the pueraria peptide, the fresh Imperata cylindrical root powder and the polygonatum sibiricum powder is 100 parts.

[0011] In a preferred embodiment, the dosage form of the composition is gummy candy, soft capsule, hard capsule, tablet or powder.

[0012] The present application also provides a preparation method of the composition for comprehensive regulation of internal environment, comprising: Step S1: selecting 1000-1200 parts of alpha-linolenic acid raw material with a purity of not less than 80% to make gummy candy; wherein the purity of the alpha-linolenic acid is not less than 80%; Step S2: selecting 100-300 parts of cordyceps militaris powder, 50-150 parts of oyster powder, 50-150 parts of ginseng powder, 50-150 parts of pueraria peptide, 50-150 parts of fresh Imperata cylindrical root powder and 50-150 parts of polygonatum sibiricum powder, and mixing the raw materials uniformly under the protection of inert gas to obtain a powder mixture; Step S3: low-temperature drying, shaping and packaging the homogenized powder mixture to make candy tablets.

[0013] In a preferred embodiment, the method further comprises the step of: low-temperature cold extraction of perilla seed oil under the protection of nitrogen to extract alpha-linolenic acid.

[0014] The composition for comprehensive regulation of internal environment and the preparation method thereof provided by the present application have at least the following beneficial effects: (1) By scientifically combining high-purity α-linolenic acid with six specific medicinal and edible homologous ingredients, a multi-level synergistic system was constructed. Among them, α-linolenic acid serves as the core driver, responsible for improving basal metabolism and insulin resistance; Cordyceps militaris powder and kudzu root peptide synergistically regulate blood sugar; fresh Imperata cylindrica root powder promotes uric acid excretion; Polygonatum odoratum powder maintains vascular health; oyster powder and ginseng powder provide trace elements and enhance the overall function of the body. Each component complements and enhances the effects on multiple targets such as "lipid reduction, circulation promotion, blood sugar stabilization, acid excretion, and repair", thereby achieving comprehensive regulation of multiple indicators such as blood lipids, blood sugar, uric acid, and blood pressure disorders. This breaks through the limitations of single-component or simple compound products and achieves comprehensive synergistic regulation of the internal environment. (2) All components are selected from the list of food and medicine homologous substances published by the National Health Commission or traditional food raw materials. They are safe and mild, and meet the needs of Chinese people for "warm nourishment and conditioning". They take into account both conditioning and repair, and have strong adaptability: This formula not only focuses on the improvement of metabolic indicators, but also provides comprehensive nutritional support for cell repair and immune function, achieving "cleansing and nourishing combination", which is more suitable for long-term conditioning. (3) Based on the defined components and proportions, and with the use of low temperature and inert gas protection in the preparation process, the stability of active ingredients such as α-linolenic acid is effectively protected. The clear formula and process ensure consistent quality between batches of the product, and the efficacy is predictable and verifiable. Attached Figure Description

[0015] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of the present invention and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 The test report shows that the composition for comprehensive internal environment regulation provided by this invention is free from other drugs with similar functions; Figure 2 A flowchart illustrating the preparation method of the composition for comprehensive internal environment regulation provided by the present invention. Detailed Implementation

[0017] To make the objectives, technical solutions, and beneficial effects of this invention clearer, the invention will be further described in detail below with reference to the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described in this specification are merely for explaining the invention and are not intended to limit the invention.

[0018] It should also be understood that the terminology used in this specification is for the purpose of describing particular embodiments only and is not intended to limit the invention. As used in this specification and the appended claims, the singular forms “a,” “an,” and “the” are intended to include the plural forms unless the context clearly indicates otherwise.

[0019] It should also be further understood that the term "and / or" as used in this specification and the appended claims refers to any combination of one or more of the associated listed items and all possible combinations, and includes such combinations.

[0020] In embodiments of the present invention, a composition for comprehensive internal environment regulation is provided, comprising a high-content α-linolenic acid as the core, compounded with various medicinal and edible ingredients, and a method for its preparation. This composition is suitable for improving the human body's metabolic internal environment and assisting in the regulation of indicators such as blood lipids, blood sugar, uric acid, and blood pressure. It should be noted that regulating various chronic diseases requires addressing the root cause, nurturing a healthy foundation, using traditional Chinese medicine logic for detoxification, anti-inflammation, phlegm removal, fat dissolution, and thrombolysis, and using nutrition to repair cell membranes and mitochondria, repair nerves, resolve organ metabolism problems, enhance immunity, and allow the body's own metabolic functions to operate normally, thus enabling health and longevity.

[0021] The composition, by weight, comprises the following components: 1000-1200 parts α-linolenic acid, 100-300 parts Cordyceps militaris powder, 50-150 parts oyster shell powder, 50-150 parts ginseng powder, 50-150 parts kudzu root peptide, 50-150 parts fresh Imperata cylindrica root powder, and 50-150 parts Polygonatum odoratum powder; wherein the purity of α-linolenic acid is not less than 80%. α-linolenic acid can be obtained by low-temperature cold extraction (or cold pressing) of perilla seed oil. For example, the purity of α-linolenic acid is 81%.

[0022] Specifically, in some preferred exemplary embodiments, the Cordyceps militaris powder is 200 parts by weight; the oyster shell powder, ginseng powder, kudzu root peptide, fresh Imperata cylindrica root powder, and Polygonatum odoratum powder are each 100 parts by weight. Meanwhile, for the convenience of user consumption and storage, the composition is available in the form of gel candies, soft capsules, hard capsules, tablets, or powders. Specifically, α-linolenic acid can be made into gel candies, and the Cordyceps militaris powder, oyster shell powder, ginseng powder, kudzu root peptide, fresh Imperata cylindrica root powder, and Polygonatum odoratum powder can be mixed and made into compressed candies.

[0023] It should be noted that the efficacy of the composition in this application originates from the individual raw materials themselves, such as... Figure 1 The test report shows that this composition does not contain any other drugs with similar functions. The individual roles of each ingredient in this composition are shown in the table below: Among them, the combination of the first five ingredients in the table above has a good effect on regulating the liver, while the combination of the first seven ingredients increases the effect on regulating the kidneys and the internal environment.

[0024] The present invention also provides a method for preparing a composition for comprehensive internal environment regulation, used to prepare the above-mentioned composition. For example... Figure 2 As shown, it includes steps S1-S3.

[0025] Step S1: Select 1000-1200 parts of α-linolenic acid raw material with a purity of not less than 80% to make gel candies; wherein, the purity of α-linolenic acid is not less than 80%; Step S2: Select 100-300 parts of Cordyceps militaris powder, 50-150 parts of oyster powder, 50-150 parts of ginseng powder, 50-150 parts of kudzu root peptide, 50-150 parts of fresh Imperata cylindrica root powder, and 50-150 parts of Polygonatum odoratum powder. Under the protection of inert gas, mix the raw materials evenly to obtain a powder mixture. Step S3: The homogenized powder mixture is dried at low temperature, shaped and packaged to make candy tablets.

[0026] Furthermore, α-linolenic acid was extracted from perilla seed oil by low-temperature cold extraction under nitrogen protection.

[0027] The beneficial effects of this composition will be illustrated below with some exemplary specific embodiments and comparative examples.

[0028] Example 1: Composition Formulation: This embodiment provides a comprehensive internal environment conditioning composition. First, 1134g of α-linolenic acid (81% purity) extracted from perilla seed oil is selected to prepare gel candies (0.7g of contents per candy); then, 200g of Cordyceps militaris powder, 100g of oyster powder, 100g of ginseng powder (artificially cultivated), 100g of kudzu root peptide, 100g of fresh Imperata cylindrica root powder, and 100g of Polygonatum odoratum powder are selected to prepare compressed candies.

[0029] Example 2: Preparation method of the composition: According to the formulation of Example 1, the preparation steps are as follows: (1) Raw material pretreatment: Cordyceps militaris, oyster, ginseng, kudzu root, fresh Imperata cylindrica root and Solomon's seal were washed and dried at a low temperature below 60℃. They were then pulverized by an ultra-micro pulverizer and passed through a 100-mesh sieve to obtain powder of each raw material. The powder was sealed and stored for later use. (2) Mixing and homogenization: In a closed mixing tank filled with nitrogen, first add Cordyceps militaris powder, oyster shell powder, ginseng powder, kudzu root peptide, fresh Imperata cylindrica root powder and Polygonatum odoratum powder, and then add them in sequence under continuous slow stirring. After the addition is complete, increase the speed and homogenize for 30 minutes under nitrogen atmosphere until a uniform powder mixture is formed; (3) Molding and packaging: Perilla seed oil α-linolenic acid is transferred to a gel candy filling machine and filled under light-proof and low temperature (<25℃) conditions to obtain gel candy; then the powder mixture is pressed into tablets in a tablet press and dried to make edible compressed candy; finally, aluminum-plastic blister packaging is carried out and covered with light-proof film.

[0030] Examples 3-5: Adjusting the amounts of each powder component (Cordyceps militaris powder, oyster shell powder, ginseng powder, kudzu root peptide, fresh Imperata cylindrica root powder, and Polygonatum odoratum powder) in Example 1 within the weight range described in claim 1, and repeating the preparation method of Example 2, the composite product was successfully obtained in both cases. Testing of the product showed that the α-linolenic acid content remained stable between 80.5% and 81.2% (tested according to GB5009.168-2016), indicating that the formulation system and process have good compatibility and stability.

[0031] Comparative Example 1: Using only the same amount of perilla seed oil α-linolenic acid as in Example 1, without adding any other powder components, it was directly filled into soft capsules of the same size.

[0032] To illustrate the overall conditioning effect of the composition of the present invention, feedback data (anonymized) from some volunteers who underwent conditioning using the product of Example 1 were collected. The results are summarized below: Case A (Blood Glucose and Uric Acid): Volunteer Mr. Zhang, 55 years old; after using the product for one month, a follow-up examination showed that his fasting blood glucose level decreased by about 1.33 mmol / L and his blood uric acid level decreased by about 156.3 μmol / L.

[0033] Case B (Blood Pressure): Volunteer Mr. Dai, with a history of hypertension; after adjusting his lifestyle and taking this product for one week under the guidance of a doctor, his fasting blood pressure in the morning decreased from 162 / 96 mmHg to 139 / 87 mmHg. Case C (Hyperuricemia): Volunteer Mr. Yin, whose original serum uric acid was 651 μmol / L; after taking this product for three weeks, his serum uric acid dropped to 288 μmol / L, and he reported that his joint discomfort had lessened. Meanwhile, feedback from similar populations regarding the pure linolenic acid product in Comparative Example 1 showed that its speed and extent of improvement on a single indicator, as well as its subjective effects on sleep, energy, etc., were inferior to the composition product in Example 1.

[0034] The above data show that the composition provided by the present invention has a more comprehensive and significant positive effect on assisting in the improvement of multiple metabolic indicators compared with single linolenic acid products.

[0035] It should be noted that this invention combines the inventor's understanding of traditional Chinese medicine and healthy nutrition, and this formula was obtained through practice. There are many successful cases, and these successful cases can be based on test reports from authoritative medical institutions (such as top-tier hospitals), ensuring that the levels of blood sugar, blood pressure, uric acid, and blood lipids are within normal ranges. It can also repair cells, enhance immunity, and thus promote physical health.

[0036] In summary, the composition for comprehensive internal environment regulation and its preparation method provided by the present invention have at least the following beneficial effects: (1) By scientifically combining high-purity α-linolenic acid with six specific medicinal and edible homologous ingredients, a multi-level synergistic system was constructed. Among them, α-linolenic acid serves as the core driver, responsible for improving basal metabolism and insulin resistance; Cordyceps militaris powder and kudzu root peptide synergistically regulate blood sugar; fresh Imperata cylindrica root powder promotes uric acid excretion; Polygonatum odoratum powder maintains vascular health; oyster powder and ginseng powder provide trace elements and enhance the overall function of the body. Each component complements and enhances the effects on multiple targets such as "lipid reduction, circulation promotion, blood sugar stabilization, acid excretion, and repair", thereby achieving comprehensive regulation of multiple indicators such as blood lipids, blood sugar, uric acid, and blood pressure disorders. This breaks through the limitations of single-component or simple compound products and achieves comprehensive synergistic regulation of the internal environment. (2) All components are selected from the list of food and medicine homologous substances published by the National Health Commission or traditional food raw materials. They are safe and mild, and meet the needs of Chinese people for "warm nourishment and conditioning". They take into account both conditioning and repair, and have strong adaptability: This formula not only focuses on the improvement of metabolic indicators, but also provides comprehensive nutritional support for cell repair and immune function, achieving "cleansing and nourishing combination", which is more suitable for long-term conditioning. (3) Based on the defined components and proportions, and with the preparation process of low temperature and inert gas protection, the stability of active ingredients such as α-linolenic acid is effectively protected; the clear formula and process ensure that the quality of the products is consistent between batches, and the efficacy is predictable and verifiable.

[0037] The present invention is not limited to the description in the specification and embodiments, and thus other advantages and modifications can be readily realized by those skilled in the art. Therefore, the present invention is not limited to the specific details, representative devices and illustrated examples shown and described herein without departing from the spirit and scope of the general concept as defined by the claims and their equivalents.

Claims

1. A composition for comprehensive conditioning of the internal environment, characterized in that, By weight, it comprises the following components: 1000-1200 parts α-linolenic acid, 100-300 parts Cordyceps militaris powder, 50-150 parts oyster shell powder, 50-150 parts ginseng powder, 50-150 parts kudzu root peptide, 50-150 parts fresh Imperata cylindrica root powder, and 50-150 parts Polygonatum odoratum powder; wherein the purity of the α-linolenic acid is not less than 80%.

2. The composition for comprehensive internal environment regulation as described in claim 1, characterized in that, The α-linolenic acid was obtained by cold extraction of perilla seed oil at low temperature.

3. The composition for comprehensive internal environment regulation as described in claim 1, characterized in that, The purity of the α-linolenic acid is 81%.

4. The composition for comprehensive internal environment regulation as described in claim 1, characterized in that, The Cordyceps militaris powder is in the amount of 200 parts by weight.

5. The composition for comprehensive internal environment regulation as described in claim 1, characterized in that, The oyster powder, ginseng powder, kudzu root peptide, fresh Imperata cylindrica root powder, and Solomon's seal powder are all in the amount of 100 parts by weight.

6. The composition for comprehensive internal environment regulation as described in claim 1, characterized in that, The composition is available in the form of gel candy, soft capsules, hard capsules, tablets, or powder.

7. A method for preparing a composition for comprehensive conditioning of the internal environment, characterized in that, include: Step S1: Select 1000-1200 parts of α-linolenic acid raw material with a purity of not less than 80% to make gel candies; wherein, the purity of the α-linolenic acid is not less than 80%; Step S2: Select 100-300 parts of Cordyceps militaris powder, 50-150 parts of oyster powder, 50-150 parts of ginseng powder, 50-150 parts of kudzu root peptide, 50-150 parts of fresh Imperata cylindrica root powder, and 50-150 parts of Polygonatum odoratum powder. Under the protection of inert gas, mix the raw materials evenly to obtain a powder mixture. Step S3: The homogenized powder mixture is dried at low temperature, shaped and packaged to produce candy tablets.

8. The method for preparing the composition for comprehensive internal environment regulation as described in claim 7, characterized in that, It also includes the step of cold extracting α-linolenic acid from perilla seed oil at low temperature under nitrogen protection.

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