Paraffin section treatment device and method

Abstract

The invention discloses a paraffin section treatment device and method. The paraffin section processing device comprises a rack, a clamping mechanism arranged on the rack through a driving mechanism, a section sending mechanism used for placing a new glass slide, a sample box used for placing a sample glass slide, a slicing machine used for cutting a paraffin block, a section mounting water tank used for receiving a sample section and a circulating mechanism used for injecting water into an inner cavity of the section mounting water tank. The edge of the top opening is provided with a receiving gap and a drainage gap at intervals; the bearing notch is formed below the discharging end of the slicing machine, and the bottom face of the bearing notch is higher than the bottom face of the drainage notch. And the driving mechanism is suitable for driving the clamping mechanism to move, so that the clamping mechanism performs a sheet taking action, or a sheet mounting action, or a water throwing action, or a sheet sending action, or a sheet placing action. Through cooperation of the sample box, the sheet mounting water tank and all the mechanisms, automatic sheet taking, sheet mounting, sheet sending and other actions of the device are achieved, and the working efficiency is improved.

Description

Technical Field

[0001] This invention relates to the field of experimental equipment technology, specifically to a paraffin section processing device and method. Background Technology

[0002] In the preparation of pathological specimens, a portion of the diseased tissue or organ is placed in paraffin for fixation. Specifically, the staff places the diseased tissue or organ in melted paraffin; after the paraffin solidifies, the tissue is encased in paraffin, forming a paraffin block; the paraffin block is then sectioned, typically with a thickness of 4μm to 6μm; the prepared paraffin section is placed in water, and because the density of paraffin is less than that of water, the paraffin section floats on the surface. The surface tension of the water naturally flattens the slightly wrinkled paraffin section, and the staff uses a glass slide to lift the section from the water, tilting the slide to remove any remaining water. The slide containing the paraffin section is then placed in an oven to bake, removing the paraffin from the interstitial spaces.

[0003] Currently, existing paraffin slicing processing devices cannot automate actions such as slice taking, mounting, and dispensing, resulting in low work efficiency and limited flexibility in use. Summary of the Invention

[0004] This invention proposes a paraffin slice processing device and method to solve the problem that existing paraffin slice processing devices cannot achieve automated slice taking, mounting, and dispensing, resulting in low work efficiency.

[0005] On one hand, the present invention discloses a paraffin slicing processing apparatus, including a frame and a clamping mechanism disposed on the frame by a drive mechanism; The rack is equipped with a storage area and a slicing area; The storage area is provided with a slide-issuing mechanism for placing new slides and a sample box for placing sample slides; a push rod is hinged to the slide-issuing mechanism; The slicing area is equipped with a slicer for cutting wax blocks, a mounting water tank for receiving sample slices, and a circulation mechanism for injecting water into the inner cavity of the mounting water tank. The top opening of the mounting tank has a receiving notch for receiving sample slices and a drainage notch for draining water spaced apart along its edge; the receiving notch is located below the output end of the slicer, and the bottom surface of the receiving notch is higher than the bottom surface of the drainage notch. The driving mechanism is adapted to drive the clamping mechanism to move so that the clamping mechanism can perform actions such as picking up a piece, mounting a piece, shaking off water, dispensing a piece, or placing a piece. The drive mechanism is also adapted to drive the clamping mechanism to push the new slide within the slide issuing mechanism via the push rod during the slide issuing action, so that the clamping part of the new slide is exposed outside the slide issuing mechanism. Through the coordination of the drive mechanism, clamping mechanism, slide issuing mechanism, sample box, microtome, mounting water tank, and circulation mechanism, the device achieves automated slide picking, mounting, and slide issuing actions, improving work efficiency.

[0006] Optionally, the film-issuing mechanism includes a film-issuing box, an elastic film support assembly, a push block, and the push rod; The hairpiece box is a hollow cavity with openings at both the top and bottom, and is mounted on the frame; the elastic support assembly is installed at the lower end of the inner cavity of the hairpiece box; the upper end of the hairpiece box has a sliding channel extending in the front-back direction, and the sliding channel penetrates the inner cavity of the hairpiece box. The inner cavity of the slide box is provided with symmetrical limiting protrusions on the left and right sides. The limiting protrusions are located between the elastic slide support assembly and the sliding channel. The bottom surface of the limiting protrusions, the inner wall of the slide box and the top surface of the elastic slide support assembly form a receiving cavity for placing stacked new glass slides. The front side wall of the hairpiece box has a hairpiece opening that communicates with the receiving cavity; The push block is slidably disposed within the sliding channel, and the lower end of the push block extends into the receiving cavity; A return spring extending in the front-to-back direction is provided between the push block and the hair-generating box; The push rod is positioned on the side of the push block away from the hairpiece opening, the push rod is hinged to the hairpiece box, and is placed within the sliding channel; The driving mechanism is adapted to drive the clamping mechanism to slide the push block via the push rod during the slide launching operation. This allows the push block to push the new slide located on the top layer within the receiving cavity, thereby causing the clamping part of the new slide on the top layer to pass through the launching port and be exposed outside the launching cassette. Using the above scheme, the cooperation of the push rod, the return spring, and the elastic slide support assembly allows the launching mechanism to complete the slide launching operation under the drive of the clamping mechanism.

[0007] Optionally, the receiving notch is opened in the front-to-back direction and is located at the rear end of the mounting plate water tank; the receiving notch is provided with a first water inlet connected to the circulation mechanism; The drainage gap is opened in the left-right direction and is located at the front end of the mounting plate water tank; the front end of the mounting plate water tank is also provided with a second water inlet connected to the circulation mechanism; The drainage notch and the second water inlet are positioned opposite each other at the left and right ends of the mounting plate water tank; The circulation mechanism is adapted to inject water into the inner cavity of the mounting water tank through the second water inlet when the slicer is cutting the wax block; The circulation mechanism is also adapted to inject water into the inner cavity of the mounting water tank through the first water inlet when the slicer cuts out waste slices. By employing the above scheme, the cooperation between the circulation mechanism and the mounting water tank allows the mounting water tank to discharge waste slices or cooperate with the clamping mechanism to perform mounting operations. The mounting water tank can be flexibly adjusted according to the slicing situation during use, thereby improving ease of use.

[0008] Optionally, a prying mechanism is provided at the receiving notch; The paddle mechanism includes a paddle lever, a motor, and a locking assembly; The lever is rotatably mounted in the inner cavity of the mounting water tank and positioned above the receiving notch; the lever extends in the left-right direction. Both ends of the lever extend outside the mounting plate water tank, one end of which is connected to the motor, and the other end is provided with a limiting ring groove that engages with the locking assembly. The motor is installed on the outer wall of the mounting tank and is adapted to drive the middle protrusion of the lever to move the sample slice between the receiving notch and the slicer; The locking assembly is rotatably mounted on the outer wall of the mounting tank. Using the above solution, a prying mechanism is added to achieve the prying action.

[0009] Optionally, the clamping mechanism includes a fixed gripper and a movable gripper; The fixed gripper is connected to the output end of the drive mechanism via a flip drive module, and the fixed gripper is provided with a mating protrusion suitable for cooperating with the push rod; The movable gripper is connected to the fixed gripper via a gripping drive module; The clamping drive module is adapted to drive the movable gripper and the fixed gripper to clamp or release the glass slide. This design enables the clamping mechanism to clamp or release the glass slide.

[0010] Optionally, a transition plate is provided between the blade of the slicer and the receiving notch; The transition plate is provided with an inclined transition surface, which is located between the bottom surface of the receiving notch and the cutting edge of the blade; The top opening of the mounting water tank is T-shaped, and the end of the mounting water tank near the slicer blade holder is provided with an arc-shaped clearance structure; The bottom surface of the receiving notch includes a horizontal bottom surface near the output end of the slicer and an arc-shaped bottom surface away from the output end of the slicer, and the arc-shaped bottom surface of the receiving notch bends downward and extends downward. The bottom surface of the drainage notch is horizontal, and the horizontal bottom surface of the receiving notch is higher than the horizontal bottom surface of the drainage notch. This design allows the receiving notch to better receive the sample slice.

[0011] Optionally, the circulation mechanism includes a water storage tank and a filter screen; The inner cavity of the water storage tank is connected to the inner cavity of the mounting plate water tank via a water pump and pipelines. The water storage tank is also adapted to receive water discharged from the drainage outlet. The filter screen is detachably mounted on the water storage tank and is suitable for filtering the water discharged from the drain opening. This design filters the waste film discharged from the drain opening, preventing it from being recycled in subsequent cycles.

[0012] Optionally, the driving mechanism includes a horizontal driving module, a vertical driving module, and a rotary driving module; The guide rail of the horizontal drive module is mounted on the frame, and the slider of the horizontal drive module is connected to the slider of the vertical drive module. The fixed end of the rotary drive module is located at the lower end of the guide rail of the vertical drive module, and the output end of the rotary drive module is connected to the clamping mechanism. The horizontal drive module is adapted to drive the clamping mechanism to move in the forward and backward directions; The output end of the rotary drive module extends in the left-right direction.

[0013] Optionally, the film-generating mechanism and the sample box are placed on top of the frame, and the mounting water tank and the slicer are placed below the frame; The mounting tank, the slide issuing mechanism, and the sample box are arranged in sequence from front to back, with the slide slicer located behind the mounting tank. The frame is provided with an opening for exposing the mounting plate water tank; The push rod is located at the rear end of the film-generating mechanism. With this design, the device's positional distribution facilitates efficient operation of the drive mechanism and clamping structure, improving work efficiency.

[0014] On the other hand, the present invention also discloses a paraffin section processing method, which, using the aforementioned paraffin section processing apparatus, includes the following steps: S1. Slide Retrieval Action: The drive mechanism cooperates with the clamping mechanism. The clamping mechanism clamps the new slide whose clamping part is exposed outside the slide issuing mechanism and pulls the new slide out of the slide issuing mechanism. S2, Mounting action: The slicer cuts the wax block; When unusable scrap pieces are cut out, the circulation mechanism injects water into the receiving gap so that the scrap pieces falling into the receiving gap are pushed by the water flow out of the drainage gap and out of the mounting water tank. When a usable sample slice is cut out, the circulation mechanism stops injecting water into the receiving notch. After the sample slice falls to the receiving notch, the drive mechanism drives the clamping mechanism holding the new slide to move to the receiving notch, so that the sample slice at the receiving notch is attached to the new slide and is taken out of the water. The sample slices are attached to a new glass slide to form the sample slide; S3, Water-spinning action: The drive mechanism drives the clamping mechanism holding the sample slide to move upward, and at the same time, the drive mechanism drives the clamping mechanism to swing, so that the water droplets attached to the sample slide are flung off. After the water-spinning action is completed, the clamping mechanism drives the clamping end of the clamping mechanism to flip the sample slide so that the sample slices on the sample slide are placed facing upwards. S4. Slide feeding action: The drive mechanism drives the clamping mechanism holding the sample slide to move from above the mounting tank to the push rod, and then moves the push rod. The actuated push rod pushes the new slide inside the slide issuing mechanism so that the new slide holding part inside the slide issuing mechanism is exposed outside the slide issuing mechanism; S5. Slide placement action: The drive mechanism drives the clamping mechanism holding the sample slide to separate from the push rod and move it to the top of the sample box; then the drive mechanism drives the clamping mechanism holding the sample slide to insert the sample slide into the sample box so that the sample slices on the sample slide are placed facing upwards. After the sample slide is inserted into the sample box, the clamping mechanism releases the sample slide, the driving mechanism drives the clamping mechanism away from the sample box, and the clamping mechanism drives the clamping end of the clamping mechanism to reset and flip. When the clamping mechanism separates from the push rod, the push rod is reset by the action of the return spring.

[0015] By adopting the above technical solution, the present invention has the following advantages compared with the prior art: Through the coordination of the drive mechanism, clamping mechanism, film dispensing mechanism, sample box, slicer, mounting water tank and circulation mechanism, the device realizes the automated actions of film picking, mounting and dispensing, and improves work efficiency. The push rod, return spring, and elastic support assembly work together to enable the launching mechanism to complete the launching action under the drive of the clamping mechanism. The combination of the circulation mechanism and the mounting water tank allows the mounting water tank to discharge waste films or cooperate with the clamping mechanism to perform mounting operations. The mounting water tank can be flexibly adjusted according to the condition of the films during use to improve ease of use. The paddle action is achieved by adding a paddle mechanism; The arrangement of the film feeding mechanism, sample box, slicer, mounting water tank, and circulation mechanism makes it easier for the drive mechanism and clamping structure to perform each action efficiently, thus improving work efficiency. As the drive mechanism, having completed the water-splashing action, moves the clamping mechanism above the sample box, the clamping mechanism actuates the push rod, causing the film-issuing mechanism to complete the film-issuing action, effectively improving work efficiency.

[0016] The above description of the disclosure and the following description of the embodiments are intended to demonstrate and explain the spirit and principles of the present invention, and to provide a further explanation of the scope of the patent application of the present invention. Attached Figure Description

[0017] The specific embodiments of the present invention will be further described in detail below with reference to the accompanying drawings.

[0018] Figure 1 This is a schematic diagram of the paraffin sectioning device performing the section taking action in this invention; Figure 2 This is a partial structural diagram of the paraffin section processing device in this invention performing the section placement action; Figure 3 This is a schematic diagram of the drive mechanism in this invention; Figure 4 This is a schematic diagram of the clamping mechanism in this invention; Figure 5 This is a partial structural diagram of the paraffin slicing processing device in this invention performing the slice-making action; Figure 6 This is a schematic diagram of the inside of the film-generating box when the push rod is not moved in this invention; Figure 7 This is a schematic diagram of the inside of the film-generating box when the push rod is moved in this invention; Figure 8 This is a schematic diagram of the structure of the hair-generating box in this invention; Figure 9 This is a schematic diagram of the mounting tank and slicer in this invention; Figure 10 for Figure 9 Enlarged view of point A in the middle; Figure 11 This is a schematic diagram of the mounting plate water tank and circulation mechanism in this invention; Figure 12 This is a partial structural diagram of the paraffin slicing device in the present invention performing the mounting action; Figure 13 This is a schematic diagram of the paddle mechanism in this invention; Figure 14 This is a schematic diagram of the locking component and the limiting ring groove engaging in the present invention; Figure 15This is a schematic diagram of the structure in this invention where the locking component is separated from the limiting ring groove; Figure 16 This is an exploded view of the mounting bracket in this invention.

[0019] Explanation of icon numbers: 1. Rack; 2. Drive mechanism; 21. Horizontal drive module; 22. Vertical drive module; 23. Rotary drive module; 3. Clamping mechanism; 31. Fixed gripper; 32. Movable gripper; 33. Clamping drive module; 34. Tilting drive module; 35. Mating protrusion; 36. Clamping connecting frame; 4. Film issuing mechanism; 41. Film issuing box; 411. Limiting protrusion; 412. Film issuing port; 413. Positioning groove; 414. Limiting slot; 42. Elastic film support assembly; 421. Base plate; 422. Top plate; 423. Support column; 424. Support spring; 43. Fixing block; 44. Pushing block; 45. Pushing rod; 46. Guide rod; 47. Return spring; 48. Pull-out plate; 5. Slicer; 51. Blade; 52. Transition plate; 521. Inclined transition surface; 6. Mounting film water tank; 61. Receiving notch; 62. Drainage notch; 63. First water inlet; 64. Second water inlet; 7. Circulation mechanism; 71. Water storage tank; 72. Water filter screen; 8. Paddle mechanism; 81. Paddle lever; 811. Limiting ring groove; 82. Motor; 83. Transmission assembly; 84. Locking assembly; 85. Mounting bracket; 851. Fixing frame; 852. Connecting plate; 853. Anchor bolt; 854. Fixing bolt; 9. Sample box; 91. Storage slot; 101. New glass slide; 102. Sample glass slide; 103. Sample section. Detailed Implementation

[0020] The following specific embodiments illustrate the implementation of the present invention. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. Although the description of the present invention is presented in conjunction with preferred embodiments, this does not mean that the features of the invention are limited to these embodiments. On the contrary, the purpose of describing the invention in conjunction with embodiments is to cover other options or modifications that may be derived based on the claims of the present invention. To provide a deep understanding of the invention, many specific details will be included in the following description. The invention may also be implemented without using these details. Furthermore, to avoid confusion or obscuring the focus of the invention, some specific details will be omitted in the description. It should be noted that, unless otherwise specified, the embodiments and features in the embodiments of the present invention can be combined with each other.

[0021] In the description of this embodiment, it should be noted that the terms "upper", "lower", "inner", "bottom", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship that the product of the invention is usually placed in during use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the present invention.

[0022] The terms “first”, “second”, etc., are used only to distinguish descriptions and should not be interpreted as indicating or implying relative importance.

[0023] In the description of this embodiment, it should also be noted that, unless otherwise explicitly specified and limited, the terms "provided with," "set up," "connected," and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this embodiment based on the specific circumstances.

[0024] On one hand, the present invention provides a paraffin slice processing apparatus. Please refer to [link / reference needed]. Figure 1 As shown, the paraffin section processing device includes a frame 1, a drive mechanism 2, a clamping mechanism 3, a section feeding mechanism 4, a sectioner 5, a mounting water tank 6, a circulation mechanism 7, and a sample box 9.

[0025] The clamping mechanism 3 is mounted on the frame 1 via the drive mechanism 2. The drive mechanism 2 is used to drive the clamping mechanism 3 to move and rotate. The frame 1 is provided with a storage area and a slicing area.

[0026] The storage area is equipped with a slide issuing mechanism 4 and a sample box 9 at intervals. In this embodiment, the slide issuing mechanism 4 is used to place new slides 101. The new slides 101 placed in the slide issuing mechanism 4 are stacked vertically (e.g., Figure 6 (As shown). The new slide 101 in the slide issuing mechanism 4 extends in the left-right direction. A push rod 45 is hinged to the slide issuing mechanism 4 for pushing the new slide 101 located at the top layer in the slide issuing mechanism 4. The top of the sample box 9 has a storage slot 91 (as shown). Figure 2 As shown, the storage slot 91 is used to place the sample slide 102. The inner wall of the storage slot 91 is provided with an inclined support surface, which is used to support the sample slide 102 so that the sample slide 102 is placed at an inclination.

[0027] The slicing area is equipped with a microtome 5, a mounting water tank 6, and a circulation mechanism 7. In this embodiment, the microtome 5 is used to cut the wax block. The mounting water tank 6 is used to receive the sample slices 103 cut by the microtome 5. The circulation mechanism 7 is used to inject water into the cavity of the mounting water tank 6 to create a water flow inside the mounting water tank 6, which is suitable for moving the sample slices 103 inside the mounting water tank 6.

[0028] Please see Figure 11 As shown, the top opening of the mounting tank 6 has a receiving notch 61 for receiving sample slices 103 and a drainage notch 62 for draining water, spaced apart along the edge of the top opening. The receiving notch 61 is located below the discharge end of the microtome 5. The bottom surface of the receiving notch 61 is higher than the bottom surface of the drainage notch 62 to ensure that water in the mounting tank 6 is discharged only through the drainage notch 62.

[0029] The drive mechanism 2 is adapted to drive the clamping mechanism 3 to move, so that the clamping mechanism 3 performs actions such as picking up films, mounting films, splashing water, dispensing films, or releasing films. In the dispensing action (e.g....) Figure 5 and Figure 7 As shown), the drive mechanism 2 is adapted to drive the clamping mechanism 3 to move. The moving clamping mechanism 3 moves the push rod 45 to swing. The swinging clamping mechanism 3 is adapted to push the new slide 101 located on the top layer in the slide issuing mechanism 4 so that the clamping part of the new slide 101 is exposed outside the slide issuing mechanism 4.

[0030] Please see Figure 1 As shown, the film issuing mechanism 4 and sample box 9 are located at the top of the frame 1, while the mounting water tank 6 and slicer 5 are located below the frame 1. The mounting water tank 6, film issuing mechanism 4, and sample box 9 are arranged sequentially from front to back. The slicer 5 is located behind the mounting water tank 6. The frame 1 has an opening to expose the mounting water tank 6, so that the drive mechanism 2 can drive the clamping mechanism 3 to move between the mounting water tank 6, film issuing mechanism 4, and sample box 9. The push rod 45 is located at the rear end of the film issuing mechanism 4. In this embodiment, please refer to... Figure 2 As shown, the top of the sample box 9 has several storage slots 91, which are arranged at intervals along the front-to-back direction.

[0031] Please see Figure 1 and Figure 2 As shown, the drive mechanism 2 includes a horizontal drive module 21, a vertical drive module 22, and a rotary drive module 23. In this embodiment, both the horizontal drive module 21 and the vertical drive module 22 are existing technologies, and the two drive modules include, but are not limited to, lead screw linear modules. The horizontal drive module 21 is suitable for driving the clamping mechanism 3 to move in the forward and backward direction. The vertical drive module 22 is suitable for driving the clamping mechanism 3 to move in the up and down direction. The rotary drive module 23 is a drive motor, and its output shaft extends in the left and right direction.

[0032] Preferably, the horizontal drive module 21 includes a lead screw guide and a nut slider that cooperate with each other. The vertical drive module 22 includes a lead screw guide and a nut slider that cooperate with each other. The lead screw guide of the horizontal drive module 21 is mounted on the frame 1. The nut slider of the horizontal drive module 21 is connected to the nut slider of the vertical drive module 22. The fixed end of the rotary drive module 23 is located at the lower end of the lead screw guide of the vertical drive module 22, and the output end of the rotary drive module 23 (i.e., the output shaft of the rotary drive module 23) is connected to the clamping mechanism 3.

[0033] Please see Figure 3 and Figure 4 As shown, the clamping mechanism 3 includes a fixed clamping jaw 31 and a movable clamping jaw 32. The fixed clamping jaw 31 is connected to the output end of the rotation drive module 23 via a flip drive module 34, and has a mating protrusion 35 suitable for engaging with the push rod 45. The movable clamping jaw 32 is connected to the fixed clamping jaw 31 via a clamping drive module 33. The clamping drive module 33 is adapted to drive the movable clamping jaw 32 and the fixed clamping jaw 31 to clamp or release the glass slide.

[0034] In this embodiment, the flip drive module 34 is a drive motor, and its output shaft extends in the front-to-back direction. The fixed ends of the flip drive module 34 and the rotary drive module 23 are respectively located on the left and right sides of the lead screw guide rail of the vertical drive module 22. The output end of the rotary drive module 23 passes through the lead screw guide rail of the vertical drive module 22 and is connected to the fixed end of the flip drive module 34 through the clamping connecting bracket 36.

[0035] In this embodiment, the fixed gripper 31 includes a connecting portion and a gripper portion. The gripper portion and the mating protrusion 35 are disposed opposite to each other at the upper and lower ends of the connecting portion. The driving end of the flipping drive module 34 is connected to the connecting portion. The movable gripper 32 is connected to the gripper portion via the clamping drive module 33. The clamping drive module 33 includes, but is not limited to, an electric actuator, a cylinder, and a hydraulic cylinder. The clamping drive module 33 is located on the side of the movable gripper 32 away from the gripper portion. The clamping drive module 33 is adapted to drive the movable gripper 32 and the gripper portion to clamp or release the glass slide.

[0036] When the clamping mechanism 3 performs the mounting action, the clamping drive module 33 is located above the movable gripper 32 (e.g., Figure 12 (as shown), to prevent the clamping drive module 33 from coming into contact with water.

[0037] Please see Figures 5-8As shown, the film issuing mechanism 4 includes a film issuing box 41, an elastic slide support assembly 42, a pusher block 44, and a pusher rod 45. The film issuing box 41 is a hollow cavity with openings at both the top and bottom, and is located at the top of the frame 1. The elastic slide support assembly 42 is installed at the lower end of the inner cavity of the film issuing box 41. A sliding channel extending in the front-back direction is provided at the upper end of the film issuing box 41, and the sliding channel passes through the inner cavity of the film issuing box 41. Limiting protrusions 411 are symmetrically provided on the left and right sides of the inner cavity of the film issuing box 41. The limiting protrusions 411 are located between the elastic slide support assembly 42 and the sliding channel. The bottom surface of the limiting protrusions 411, the inner side wall of the film issuing box 41, and the top surface of the elastic slide support assembly 42 form a receiving cavity for placing stacked new glass slides 101.

[0038] The front sidewall of the slide cassette 41 has a slide inlet 412 communicating with the receiving cavity. Preferably, the thickness of a single new slide 101 is N mm. The distance between the top and bottom surfaces of the inner wall of the slide inlet 412 is greater than or equal to N mm and less than 2 N mm. A pusher block 44 is slidably disposed within a sliding channel. The lower end of the pusher block 44 extends into the receiving cavity, and its front sidewall is adapted to abut against the rear sidewall of the new slide 101 located on the top layer. Preferably, the height difference between the lower end surface of the pusher block 44 and the bottom surface of the limiting protrusion 411 is greater than zero and less than or equal to the thickness of a single new slide 101. A return spring 47 extending in the front-rear direction is provided between the pusher block 44 and the slide cassette 41. A pusher rod 45 is positioned on the side of the pusher block 44 away from the slide inlet 412. The middle part of the push rod 45 is hinged to the film release box 41, the lower end of the push rod 45 is placed in the sliding channel, and the upper end of the push rod 45 is exposed outside the film release box 41.

[0039] During the slide delivery operation, the drive mechanism 2 is adapted to drive the mating protrusion 35 of the clamping mechanism 3, so that the mating protrusion 35 drives the push block 44 to slide via the push rod 45, so that the push block 44 pushes the new slide 101 located on the top layer in the receiving cavity, thereby causing the clamping part of the new slide 101 located on the top layer to pass through the delivery port 412 and be exposed outside the delivery box 41 (e.g., Figure 7 (As shown). During the film-laying action, the push rod 45 and the push block 44 engage in contact.

[0040] The working principle of the film-generating mechanism 4 is as follows: When push lever 45 is not moved (e.g.) Figure 6 As shown), the push rod 45 is vertically positioned, with its bottom higher than the lower end face of the push block 44, and its top exposed outside the film cassette 41. At this time, the push block 44, under the action of the return spring 47, is positioned behind the stacked new slides 101 and spaced apart from the stacked new slides 101.

[0041] When the upper end of the push rod 45 is swung backward by the protrusion 35, it is as follows (e.g.) Figure 7As shown), the film issuing mechanism 4 performs the film issuing action. Specifically, the lower end of the push rod 45 pushes the push block 44 forward, so that the push block 44 pushes the new slide 101 located on the top layer in the receiving cavity forward, thereby causing the clamping part of the new slide 101 located on the top layer in the receiving cavity to pass through the film issuing port 412 and be exposed outside the film issuing box 41.

[0042] When the mating protrusion 35 separates from the push rod 45, the push block 44 is reset backward under the action of the return spring 47; the push block 44, which is reset backward, pushes the lower end of the push rod 45 so that the push rod 45 is reset to the vertical setting state.

[0043] After the new slide 101 exposed outside the slide box 41 is removed by the clamping mechanism 3 (as shown in the image) Figure 6 As shown), the new glass slides 101 stacked in the receiving cavity move upward under the action of the elastic support assembly 42, so that the new glass slides 101 located at the top layer in the receiving cavity abut against the bottom surface of the limiting protrusion 411. At this time, the push block 44 is placed behind the stacked new glass slides 101 and is spaced apart from the stacked new glass slides 101, waiting for the protrusion 35 to move the push rod 45 again.

[0044] In this embodiment, in order to ensure that the protrusion 35 effectively moves the push rod 45, the protrusion 35 is provided with an arc-shaped notch that cooperates with the push rod 45.

[0045] In some embodiments, a torsion spring can be provided between the film-generating box 41 and the push rod 45 to ensure that the push rod 45 remains vertical in its free state.

[0046] Furthermore, to improve the stability of the film-generating mechanism 4, a fixing block 43 is provided within the sliding channel. The left and right ends of the fixing block 43 are respectively fixedly connected to the film-generating box 41 by bolts. (See also...) Figure 6 As shown, the feeding port 412, fixing block 43, pushing block 44, and pushing rod 45 are arranged sequentially from front to back. The fixing block 43 is positioned above the limiting protrusion 411. The pushing block 44 is slidably connected to the fixing block 43 via a guide rod 46. The guide rod 46 extends in the front-to-back direction, with one end fixed to the pushing block 44 by a bolt, and the other end slidably passing through the fixing block 43. A return spring 47 is sleeved on the guide rod 46 and positioned between the fixing block 43 and the pushing block 44. Both ends of the return spring 47 abut against the fixing block 43 and the pushing block 44, respectively.

[0047] In some embodiments, the end of the guide rod 46 away from the push block 44 is provided with a limiting flange, which is located on the side of the fixing block 43 away from the push block 44 (not shown in the figure). By providing the limiting flange, the guide rod 46 is prevented from accidentally disengaging from the fixing block 43, thereby limiting the sliding range of the push block 44 in the front-back direction.

[0048] For further details, please refer to Figure 6 As shown, the elastic support assembly 42 includes a base plate 421, a top plate 422, support columns 423, and support springs 424. In this embodiment, the base plate 421 is horizontally arranged. There are four support columns 423, distributed at the four corners of the base plate 421. The support columns 423 are vertically arranged and fixed to the top of the base plate 421. The top plate 422 is horizontally arranged and placed above the base plate 421. The four corners of the top plate 422 are slidably connected to the corresponding support columns 423. A support spring 424 is provided between the base plate 421 and the top plate 422, and the support spring 424 is sleeved on the corresponding support column 423. The upper and lower ends of the support spring 424 are connected to the base plate 421 and the top plate 422, respectively. The inner cavity of the dispensing box 41 is provided with a positioning groove 413 (e.g., Figure 8 (As shown). The upper end of the support column 423 slides through the top plate 422 and is adapted to be inserted into the positioning groove 413 to position the elastic slide assembly 42. The top surface of the top plate 422 is adapted to place the stacked new slides 101. The four support columns 423 are distributed on the left and right sides of the stacked new slides 101.

[0049] Furthermore, to ensure that the new slide 101 within the receiving cavity passes smoothly through the slide opening 412, please refer to... Figure 8 As shown, the front and rear ends of the receiving cavity are respectively provided with limiting slots 414 to limit the left and right sides of the new glass slide 101.

[0050] For further details, please refer to Figure 6 As shown, the film issuing mechanism 4 also includes a pull-out plate 48. A pull-out slot is provided at the bottom of the film issuing box 41. The pull-out slot extends in the left-right direction. The pull-out plate 48 is inserted into the pull-out slot to seal the lower opening of the film issuing box 41. A flexible film support assembly 42 is placed on top of the pull-out plate 48.

[0051] Please see Figure 9 As shown, the slicer 5 is prior art. Chinese patent document CN220960846U describes a shatterproof paraffin slicer. Therefore, this application will not elaborate on the structure of the slicer 5.

[0052] Please see Figure 9 and Figure 10 As shown, a transition plate 52 is provided between the blade 51 of the slicer 5 and the receiving notch 61. The transition plate 52 is fixed to the blade holder of the slicer 5. An inclined transition surface 521 is provided on the transition plate 52. The inclined transition surface 521 is positioned between the bottom surface of the receiving notch 61 and the cutting edge of the blade 51. The angle between the inclined transition surface 521 and the horizontal plane is 5° to 10°.

[0053] In this embodiment, the top opening of the mounting plate water tank 6 is T-shaped (e.g., Figure 11(As shown). The bottom of the mounting water tank 6 near the blade holder of the slicer 5 is provided with an arc-shaped clearance structure. The transition plate 52 is provided with a clearance notch, which is located below the inclined transition surface 521 to avoid the edge of the mounting water tank 6.

[0054] Please see Figure 11 and Figure 12 As shown, the receiving notch 61 is opened along the front-to-back direction and is located at the rear end of the mounting water tank 6. A first water inlet 63 connected to the circulation mechanism 7 is provided at the receiving notch 61. A drain notch 62 is opened along the left-to-right direction and is located at the rear end of the mounting water tank 6. A second water inlet 64 connected to the circulation mechanism 7 is also provided at the rear end of the mounting water tank 6. The drain notch 62 and the second water inlet 64 are positioned opposite each other at the left and right ends of the mounting water tank 6.

[0055] In this embodiment, the T-shaped top opening of the mounting tank 6 includes a receiving section extending in the front-to-back direction and a drainage section extending in the left-to-right direction. The receiving section has a receiving notch 61 at its rear end. The front end of the receiving section is connected to the middle of the drainage section. The left and right ends of the drainage section each have drainage notches 62 and a second water inlet 64. The width of the receiving section in the left-to-right direction is greater than the width of the new glass slide 101.

[0056] Furthermore, the bottom surface of the receiving notch 61 includes a horizontal bottom surface near the discharge end of the slicer 5 (i.e., near the blade 51) and an arc-shaped bottom surface away from the discharge end of the slicer 5 (i.e., away from the blade 51). In this embodiment, the arc-shaped bottom surface of the receiving notch 61 is located behind the arc-shaped bottom surface of the receiving notch 61. The arc-shaped bottom surface of the receiving notch 61 bends downward and extends forward. The arc-shaped bottom surface of the receiving notch 61 can better fit the arc-shaped clearance structure of the mounting water tank 6, and at the same time, it is more conducive to the water discharged from the first inlet 63 flowing to the drain notch 62. In addition, the downward bending of the arc-shaped bottom surface of the receiving notch 61 can deepen the water depth at the receiving notch 61, which is convenient for the sample slice 103 to be flattened so that the sample slice 103 at the receiving notch 61 can be attached to the new glass slide 101. Furthermore, the bottom surface of the inner cavity of the mounting water tank 6 corresponding to the receiving section is higher than the bottom surface of the inner cavity of the mounting water tank 6 corresponding to the drain section.

[0057] The bottom surface of the drainage gap 62 is a horizontal bottom surface, and the horizontal bottom surface of the receiving gap 61 is higher than the horizontal bottom surface of the drainage gap 62.

[0058] When the slicer 5 cuts the wax block, the circulation mechanism 7 is adapted to inject water into the inner cavity of the mounting water tank 6 through the second water inlet 64, so that a directional water flow is formed at the drainage section, and the water flow direction at the drainage section is from right to left. When the slicer 5 cuts the wax block and cuts out waste slices, the circulation mechanism 7 is adapted to inject water into the inner cavity of the mounting water tank 6 through the first water inlet 63, so that a directional water flow is formed at the receiving section, and the water flow direction at the receiving section is from back to front.

[0059] The working principle of mounting plate water tank 6 is as follows: When the slicer 5 initially cuts the wax block and the resulting sample slice 103 is an unusable waste slice, the circulation mechanism 7 injects water into the inner cavity of the mounting water tank 6 through the first water inlet 63 and the second water inlet 64. When the waste slice falls to the receiving notch 61, the water flow at the receiving section moves the waste slice forward, allowing it to flow to the drainage section; then, the water flow at the drainage section moves the waste slice to the left, allowing it to be discharged out of the mounting water tank 6 through the drainage notch 62.

[0060] When the microtome 5 cuts the wax block and the resulting sample slice 103 is usable, the first water inlet 63 stops injecting water into the mounting tank 6 to prevent the slice at the receiving notch 61 from moving to the drainage section. Once the slice reaches the receiving notch 61, the device performs subsequent mounting operations. During this period, whether or not the second water inlet 64 injects water into the mounting tank 6 will not affect the state of the slice; therefore, the second water inlet 64 can inject water into the mounting tank 6 through the circulation mechanism 7, and the second water inlet 64 can also stop injecting water into the mounting tank 6.

[0061] Preferably, during this period, the second water inlet 64 continues to inject water into the inner cavity of the mounting tank 6 through the circulation mechanism 7 to ensure that the mounting tank 6 and the circulation mechanism 7 are always in a state of circulation. In addition, the second water inlet 64 continuing to inject water into the inner cavity of the mounting tank 6 through the circulation mechanism 7 can help the sample slice 103 flatten in the receiving section of the mounting tank 6, so as to facilitate subsequent mounting operations.

[0062] Furthermore, to ensure that the water flow can effectively drive the waste film to circulate, both the first water inlet 63 and the second water inlet 64 are located in the upper middle part of the mounting water tank 6, and the horizontal height of both water inlets is lower than the horizontal height of the bottom surface of the drainage notch 62. Preferably, in the vertical direction, the distance between the top surface of the inner wall of the first water inlet 63 and the second water inlet 64 and the bottom surface of the drainage notch 62 is 1mm to 50mm.

[0063] Please see Figure 11 As shown, the circulation mechanism 7 includes a water storage tank 71 and a filter screen 72. The water storage tank 71 is connected to the inner cavity of the mounting plate water tank 6 (not shown) via a water pump and pipeline. The water storage tank 71 is also adapted to receive water discharged from the drain outlet 62. The filter screen 72 is detachably mounted on the water storage tank 71 and is adapted to filter the water discharged from the drain outlet 62.

[0064] In this embodiment, a guide plate is provided at the edge of the drainage notch 62. A reinforcing rib is provided between the guide plate and the film-mounting water tank 6, and the reinforcing rib is located on the lower surface of the guide plate. A water storage tank 71 is located below the guide plate. The water storage tank 71 is a cavity with an open top. A filter screen 72 is snapped onto the top of the water storage tank 71 and is located directly below the guide plate. The filter screen 72 is suitable for filtering waste film to prevent the waste film from circulating.

[0065] In this embodiment, the circulation mechanism 7 also includes a solenoid valve (not shown in the figure) for controlling the opening and closing of the pipeline. The number of solenoid valves includes, but is not limited to, one or two.

[0066] When there is one solenoid valve and one water pump, the solenoid valve has one inlet and two outlets. The inlet of the solenoid valve is connected to the inner cavity of the water storage tank 71 via the water pump. One outlet of the solenoid valve is connected to the first inlet 63 via a first pipe, and the other outlet is connected to the second inlet 64 via a second pipe. The flow between the first inlet 63, the second inlet 64, and the water pump outlet is controlled by the solenoid valve. Both the first and second pipes are fixed to the outer walls of the mounting plate water tank 6 and the water storage tank 71 via pipe clamps. Both the first and second pipes are equipped with one-way valves to prevent water in the mounting plate water tank 6 from flowing back into the water storage tank 71 through either the first or second pipe.

[0067] When there are two solenoid valves and one water pump, the water pump inlet is connected to the inner cavity of the water storage tank 71, and the water pump outlet is connected through the inlet end of the diverter pipe. The first outlet end of the diverter pipe is connected to the first inlet 63, and a solenoid valve is installed between them. The second outlet end of the diverter pipe is connected to the second inlet 64, and another solenoid valve is installed between them. The two solenoid valves control the opening and closing of their respective pipelines.

[0068] In this embodiment, the water pump is a circulating water pump, which is existing technology and will not be described in detail. Both the water pump and the solenoid valve are installed on the outer or inner wall of the water storage tank 71 (not shown in the figure). Neither the water pump nor the solenoid valve comes into direct contact with water, effectively protecting them. The water pump inlet is connected to the inner cavity of the water storage tank 71 via a pipeline.

[0069] Please see Figures 11-13 As shown, the sample slice 103 is effectively moved between the blade 51 and the receiving notch 61. The receiving notch 61 is equipped with a moving mechanism 8. The moving mechanism 8 includes a moving rod 81, a motor 82, and a locking assembly 84. The moving rod 81 is rotatably mounted in the inner cavity of the mounting tank 6 and positioned above the receiving notch 61. The moving rod 81 extends in the left-right direction, with both ends extending outside the mounting tank 6. One end of the moving rod 81 is connected to the motor 82, and the other end of the moving rod 81 is provided with a limiting annular groove 811 that engages with the locking assembly 84.

[0070] In this embodiment, the paddle lever 81 includes a first shaft, a lever, and a second shaft connected in sequence. The axis of the first shaft coincides with the axis of the second shaft. The end of the first shaft is connected to one end of the lever via a corresponding radial extension, and the end of the second shaft is connected to the other end of the lever via a corresponding radial extension. The lever and its radial extensions at both ends constitute the middle section protrusion of the paddle lever 81, and the middle section protrusion is located in the inner cavity of the mounting tank 6. The lever has an arc-shaped surface, suitable for moving the sample slice 103 between the receiving notch 61 and the blade 51.

[0071] The specific paddle action of the paddle mechanism 8 is as follows: When the slicer 5 cuts the wax block and produces waste slices, the motor 82 drives the lever 81 to rotate, causing the lever 81 to move the waste slices, thus separating the waste slices from the blade 51. The waste slices then slide to the receiving notch 61 and drain through the drainage notch 62 to the outside of the mounting tank 6. When the slicer 5 cuts the wax block and produces usable slices, after cutting the required number (one or two slices), the motor 82 drives the lever 81 to rotate, causing the slices to separate from adjacent slices or from the blade 51. This allows the usable slices to flow to the receiving section of the mounting tank 6 for subsequent mounting operations.

[0072] The locking assembly 84 and the motor 82 are respectively located on the left and right sides of the mounting tank 6. The motor 82 is mounted on the right outer wall of the mounting tank 6 via a mounting bracket 85. The output shaft of the motor 82 is connected to one end of the lever 81 via a transmission assembly 83. The motor 82 is adapted to drive the protrusion in the middle section of the lever 81 to actuate the sample slice 103 between the receiving notch 61 and the actuating blade 51. The locking assembly 84 is rotatably mounted on the left outer wall of the mounting tank 6.

[0073] When the lever mechanism 8 completes the lever action or is in an idle state, the middle section of the lever rod 81 is convex with the arc-shaped surface facing upward, that is, the middle section of the lever rod 81 is positioned above the liquid surface in the mounting water tank 6 and does not come into contact with the water in the mounting water tank 6.

[0074] In this embodiment, the conveying assembly 83 includes a conveyor belt, a driving wheel, and a driven wheel. The driving wheel is connected to the output shaft of the motor 82. The right end of the lever 81 passes through the mounting water tank 6 and is connected to the driven wheel. The locking assembly 84 limits the left end of the lever 81 to prevent the lever 81 from accidentally disengaging from the mounting water tank 6. The locking assembly 84 includes a locking hook rotatably connected to the mounting water tank 6. The locking hook is rotatably connected to the mounting water tank 6 via a pin. The pin extends in the left-right direction, and a rubber pad is provided between the end of the pin and the locking hook to increase the friction between the locking hook and the pin, thereby preventing the locking hook from rotating accidentally.

[0075] Furthermore, the mounting water tank 6 is provided with an assembly hole through which the lever 81 passes. This assembly hole is positioned higher than the horizontal bottom surface of the receiving notch 61, ensuring that water inside the mounting water tank 6 will not leak out through the assembly hole. The end of the lever 81 furthest from the motor 82 is rotatably connected to the mounting water tank 6 via a bearing housing, and a sealing ring is provided between the bearing housing and the mounting water tank 6. The end of the lever 81 closest to the motor 82 is connected to the driven wheel via a coupling.

[0076] When it is necessary to replace the lever 81, rotate the locking hook to disengage it from the limiting ring groove 811 (e.g., Figure 15 (As shown), to facilitate subsequent disassembly operations. After installing the new lever 81 on the mounting plate water tank 6, rotate the locking hook to engage it with the limiting ring groove 811 (as shown). Figure 14 (As shown).

[0077] In this embodiment, to ensure the conveyor belt can be effectively tensioned, please refer to... Figure 12 , Figure 13 and Figure 16 As shown, the mounting bracket 85 includes a fixed frame 851 and a connecting plate 852. A connecting slider is fitted onto the fixed end of the motor 82, and the connecting slider is connected to the motor 82 by bolts. The fixed frame 851 is a cavity with an open left end and a closed right end. The inner cavity of the fixed frame 851 is a sliding groove extending in the left-right direction, and the connecting slider is slidably connected to the sliding groove. The connecting plate 852 is installed at the left end opening of the fixed frame 851, and its four corners are connected to the fixed frame 851 by bolts. The drive wheel is connected to the output shaft of the motor 82 and exposed outside the fixed frame 851. The fixed end of the motor 82 extends to the outside of the fixed frame 851 in the left-right direction so that the motor 82's cable can be connected to external cables. The driven wheel is rotatably mounted on the fixed frame 851 and located behind the drive wheel.

[0078] A clamping bolt 853 is provided between the connecting slider and the connecting plate 852. The clamping bolt 853 extends in the left-right direction, and its screw end is threadedly connected to the connecting plate 852 and extends into the fixed frame 851 to abut against the connecting slider. The tension of the conveyor belt can be adjusted by rotating the clamping bolt 853.

[0079] Furthermore, the mounting bracket 85 has oblong holes at both its top and bottom. These oblong holes extend in the left-right direction. A fixing bolt 854 is provided between the connecting slider and the mounting bracket 85. The fixing bolt 854 is vertically positioned. When the tightening bolt 853 effectively abuts against the connecting slider, the thread of the fixing bolt 854 is adapted to pass through the oblong hole and be threadedly connected to the connecting slider, so that the nut of the fixing bolt 854 abuts against the mounting bracket 85, thereby limiting the position of the connecting slider.

[0080] In this embodiment, the paraffin slicing processing device further includes a controller. The controller is electrically connected to each drive module in the drive mechanism 2 and each drive module in the clamping mechanism 3 to control the drive mechanism 2 and the clamping mechanism 3 to perform slice picking, slice mounting, water removal, slice dispensing, and slice placement actions. The connection between the controller and the drive modules is prior art and will not be described in detail. The controller includes, but is not limited to, a PLC controller.

[0081] On the other hand, the present invention also provides a paraffin section processing method, which uses the above-mentioned paraffin section processing apparatus and includes the following steps: S1. Film retrieval action: such as... Figure 1 As shown, the drive mechanism 2 cooperates with the clamping mechanism 3. The clamping mechanism 3 clamps the new glass slide 101 whose clamping part is exposed outside the glass slide issuing mechanism 4 and pulls the new glass slide 101 out of the glass slide issuing mechanism 4.

[0082] Specifically, the clamping drive module 33 drives the movable gripper 32 and the gripper portion to the open state, and the drive mechanism 2 drives the clamping mechanism 3 to move to the vicinity of the opening 412 of the developing cassette 41, so that the movable gripper 32 and the gripper portion are positioned on the upper and lower sides of the new slide 101 exposed outside the developing cassette 41. Then, the clamping drive module 33 drives the movable gripper 32 and the gripper portion to close, so that the clamping mechanism 3 clamps the new slide 101. After the clamping mechanism 3 clamps the new slide 101, the drive mechanism 2 drives the clamping mechanism 3 to move forward, so that the clamping mechanism 3 pulls the new slide 101 out of the developing cassette 41, that is, the new slide 101 is completely separated from the developing cassette 41.

[0083] In S1, the protrusion 35 is positioned above the fixed gripper 31, and the movable gripper 32 is positioned above the gripper portion. After the slide retrieval operation is completed, no new slide 101 is exposed outside the slide retrieval box 41 at the slide retrieval opening 412 (e.g., Figure 6 (As shown).

[0084] S2. Mounting Action: The microtome 5 cuts the wax block; when unusable waste slides are cut out, the circulation mechanism 7 injects water into the receiving notch 61, so that the waste slides falling into the receiving notch 61 are pushed by the water flow and discharged from the drain notch 62 to the outside of the mounting water tank 6; when a usable sample slide 103 is cut out, the circulation mechanism 7 stops injecting water into the receiving notch 61. After the sample slide 103 falls into the receiving notch 61, the drive mechanism 2 drives the clamping mechanism 3 holding the new slide 101 to move to the receiving notch 61, so that the sample slide 103 at the receiving notch 61 is attached to the new slide 101 and is taken out of the water (e.g., Figure 12 (As shown). Among them, sample slice 103 is attached to new slide 101 to form sample slide 102.

[0085] Specifically, when unusable scrap pieces are cut out, the motor 82 drives the lever 81 to rotate, causing the lever 81 to agitate the scrap piece, thereby separating it from the blade 51. The agitated scrap piece slides down the inclined transition surface 521 and falls into the receiving notch 61. During this process, the circulation mechanism 7 injects water into the inner cavity of the mounting tank 6 through the first inlet 63 and the second inlet 64. After the agitated scrap piece falls into the receiving notch 61 under the guidance of the inclined transition surface 521, it moves forward under the push of the water flow at the receiving section, allowing it to flow to the drainage section. Then, under the push of the water flow at the drainage section, the scrap piece moves to the left, allowing it to be discharged through the drainage notch 62 out of the mounting tank 6 (i.e., into the filter screen 72). Waste film is filtered by the filter screen 72 and remains on the filter screen 72, while the remaining water discharged through the drain opening 62 enters the water storage tank 71 through the filter screen 72. The water in the water storage tank 71 can circulate with the water in the mounting tank 6 under the action of the water pump.

[0086] When usable sample slices 103 are cut, after cutting the required number (one or two slices) and ensuring there are no waste slices at the receiving section, the motor 82 drives the pry bar 81 to rotate, so that the sample slice 103 separates from the adjacent sample slice 103, or separates the sample slice 103 from the blade 51; the prying sample slice 103 slides down the inclined transition surface 521 under the guidance of the blade 521 to the receiving notch 61. During this period, the first water inlet 63 stops injecting water into the inner cavity of the mounting water tank 6, while the second water inlet 64 continues to inject water into the inner cavity of the mounting water tank 6. After the prying sample slice 103 falls to the receiving notch 61 under the guidance of the inclined transition surface 521, the sample slice 103 in contact with the water flattens out in the mounting water tank 6. Then, the drive mechanism 2 drives the clamping mechanism 3 holding the new slide 101 to move to the receiving notch 61, so that the sample slice 103 at the receiving notch 61 is attached to the new slide 101 and is taken out of the water to form the sample slide 102.

[0087] In S2, the protrusion 35 is positioned above the fixed gripper 31, the movable gripper 32 is positioned above the gripper portion, and the sample slice 103 on the sample slide 102 is placed downwards.

[0088] S3, Water-spinning action: The drive mechanism 2 drives the clamping mechanism 3 holding the sample slide 102 to move upward, and at the same time, the drive mechanism 2 drives the clamping mechanism 3 to swing so that the water droplets attached to the sample slide 102 are shaken off; after the water-spinning action is completed, the clamping mechanism 3 drives the clamping end of the clamping mechanism 3 to rotate the sample slide 102 so that the sample slice 103 on the sample slide 102 is placed facing upward.

[0089] Specifically, the vertical drive module 22 drives the clamping mechanism 3 holding the sample slide 102 to move upward, while the rotation drive module 23 drives the clamping mechanism 3 to swing back and forth at a low speed to ensure that while the water droplets are shaken off, the sample slice 103 remains effectively attached to the sample slide 102. After the water-swinging action is completed, the sample slide 102 is set horizontally with the sample slice 103 on the sample slide 102 facing downward. Then, the flip drive module 34 drives the clamping end of the clamping mechanism 3 (i.e., the fixed jaw 31 and the movable jaw 32) to rotate 180° so that the sample slice 103 on the sample slide 102 is placed upward, with the protrusion 35 located below the fixed jaw 31, so that the subsequent slide placement action can be performed.

[0090] S4. Slide feeding action: The drive mechanism 2 drives the clamping mechanism 3 holding the sample slide 102 to move from above the mounting tank 6 to the push rod 45, and moves the push rod 45 (e.g., Figure 5 As shown), the actuated push rod 45 pushes the new slide 101 inside the slide issuing mechanism 4, so that the clamping part of the new slide 101 inside the slide issuing mechanism 4 is exposed outside the slide issuing mechanism 4 (as shown). Figure 7 (As shown).

[0091] Specifically, after the device completes the water-spraying action, the clamping mechanism 3 is positioned above the mounting water tank 6, with the cooperating protrusion 35 located below the fixed gripper 31. The horizontal drive module 21 drives the clamping mechanism 3 holding the sample slide 102 to move backward, causing the cooperating protrusion 35 to actuate the upper end of the push rod 45 to swing backward, and the lower end of the push rod 45 to push the push block 44 forward. The forward-moving push block 44 pushes the new slide 101 located on the top layer in the receiving cavity forward, thereby causing the clamping part of the new slide 101 located on the top layer in the receiving cavity to pass through the opening 412 and be exposed outside the opening cassette 41 (e.g., Figure 7 (As shown).

[0092] Specifically, when a new slide 101 within the receiving cavity is partially pushed outside the slide cassette 41, the portion of the new slide 101 exposed outside the slide cassette 41 is merely a clamping area (i.e., a clamping region) for the operator to hold or for the clamping mechanism 3 to hold, rather than the area in contact with the wax sheet (i.e., the attachment region). Furthermore, the side of the new slide 101 furthest from the limiting protrusion 411 is used for wax sheet attachment. Therefore, when the operator does not remove the new slide 101 from the slide inlet 412, the attachment region of the new slide 101 will not be exposed outside the slide cassette 41, meaning the attachment region will not be contaminated by external factors.

[0093] S5. Slide Placement Action: The drive mechanism 2 drives the clamping mechanism 3 holding the sample slide 102 to separate from the push rod 45 and move it above the sample box 9; then the drive mechanism 2 drives the clamping mechanism 3 holding the sample slide 102 to insert the sample slide 102 into the sample box 9, so that the sample slice 103 on the sample slide 102 is placed facing upwards (e.g., Figure 2 (as shown) After the sample slide 102 is inserted into the sample container 9, the clamping mechanism 3 releases the sample slide 102, the driving mechanism 2 drives the clamping mechanism 3 away from the sample container 9, and the clamping end of the clamping mechanism 3 is reset and flipped. When the clamping mechanism 3 separates from the push rod 45, the push rod 45 is reset by the action of the reset spring 47.

[0094] Specifically, the horizontal drive module 21 continues to drive the clamping mechanism 3 holding the sample slide 102 to move backward, so that the clamping mechanism 3 is positioned above the storage slot 91. The rotation drive module 23 drives the clamping mechanism 3 holding the sample slide 102 to rotate, so that the sample slide 102 is tilted (e.g., Figure 2 (As shown). The vertical drive module 22 drives the clamping mechanism 3 to insert the sample slide 102 into the storage slot 91. After the sample slide 102 is inserted into the storage slot 91, the clamping drive module 33 drives the movable jaw 32 and the jaw part to open, so that the clamping mechanism 3 releases the sample slide 102. Then, the drive mechanism 2 drives the clamping mechanism 3 away from the sample box 9, and the flip drive module 34 drives the clamping end of the clamping mechanism 3 (i.e., the fixed jaw 31 and the movable jaw 32) to flip 180° to achieve a reset flip. At this time, the mating protrusion 35 is located above the fixed jaw 31, and the movable jaw 32 is located above the jaw part.

[0095] During operation, the paraffin section processing device performs a water-spraying action. Therefore, as the clamping mechanism 3 moves from above the mounting water tank 6 to above the sample box 9, water droplets will not fall onto the sheet-issuing mechanism 4. During the movement of the clamping mechanism 3 from above the mounting water tank 6 to above the sample box 9, the sheet-issuing mechanism 4 is driven to perform the sheet-issuing action, achieving a coordinated effect.

[0096] This invention achieves automated slide picking, mounting, and slide dispensing through the coordination of a drive mechanism, clamping mechanism, slide dispensing mechanism, sample box, microtome, mounting water tank, and circulation mechanism, thereby improving work efficiency. The push rod, return spring, and elastic slide support assembly work together to allow the slide dispensing mechanism to complete the dispensing action under the drive of the clamping mechanism. The circulation mechanism and mounting water tank work together to allow the mounting water tank to discharge waste slides or assist the clamping mechanism in mounting actions. The mounting water tank can be flexibly adjusted according to the slide conditions during use, improving ease of use. A slide-picking mechanism is added to achieve the slide-picking action. The positional distribution of the slide dispensing mechanism, sample box, microtome, mounting water tank, and circulation mechanism facilitates efficient operation of each action by the drive mechanism and clamping structure, improving work efficiency. When the drive mechanism, after completing the water-spraying action, moves the clamping mechanism above the sample box, the clamping mechanism actuates the push rod, causing the slide dispensing mechanism to complete the slide dispensing action, effectively improving work efficiency.

[0097] The above embodiments are merely illustrative of the principles and effects of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by those skilled in the art without departing from the spirit and technical concept disclosed in the present invention should still be covered by the claims of the present invention.

Claims

1. A paraffin slicing processing device, characterized in that, Includes a frame (1) and a clamping mechanism (3) mounted on the frame (1) via a drive mechanism (2); The rack (1) is provided with a storage area and a slicing area; The storage area is provided with a slide-dispensing mechanism (4) for placing new slides (101) and a sample box (9) for placing sample slides (102); a push rod (45) is hinged to the slide-dispensing mechanism (4). The slicing area is equipped with a slicer (5) for cutting wax blocks, a mounting water tank (6) for receiving sample slices (103), and a circulation mechanism (7) for injecting water into the inner cavity of the mounting water tank (6). The top opening of the mounting tank (6) has a receiving notch (61) for receiving sample slices (103) and a drainage notch (62) for draining water at intervals along the edge of the top opening; the receiving notch (61) is located below the discharge end of the slicer (5), and the bottom surface of the receiving notch (61) is higher than the bottom surface of the drainage notch (62). The driving mechanism (2) is adapted to drive the clamping mechanism (3) to move so that the clamping mechanism (3) can perform a film picking action, or a film mounting action, or a water-spraying action, or a film dispensing action, or a film releasing action. The drive mechanism (2) is also adapted to drive the clamping mechanism (3) to push the new slide (101) in the slide issuing mechanism (4) through the push rod (45) during the slide issuing action, so that the clamping part of the new slide (101) is exposed outside the slide issuing mechanism (4).

2. The paraffin slice processing apparatus according to claim 1, characterized in that, The film-issuing mechanism (4) includes a film-issuing box (41), an elastic film support assembly (42), a push block (44), and the push rod (45). The hairpiece box (41) is a hollow cavity with openings at both the top and bottom, and is mounted on the frame (1); the elastic support assembly (42) is installed at the lower end of the inner cavity of the hairpiece box (41); the upper end of the hairpiece box (41) is provided with a sliding channel extending in the front-back direction, and the sliding channel penetrates the inner cavity of the hairpiece box (41). The inner cavity of the slide holder (41) is provided with symmetrical limiting protrusions (411) on the left and right sides. The limiting protrusions (411) are located between the elastic slide assembly (42) and the sliding channel. The bottom surface of the limiting protrusions (411), the inner side wall of the slide holder (41) and the top surface of the elastic slide assembly (42) form a receiving cavity for placing stacked new glass slides (101). The front side wall of the hairpiece box (41) is provided with a hairpiece opening (412) that communicates with the receiving cavity. The push block (44) is slidably disposed in the sliding channel, and the lower end of the push block (44) extends into the receiving cavity; A return spring (47) extending in the front-rear direction is provided between the push block (44) and the film box (41). The push rod (45) is placed on the side of the push block (44) away from the hair opening (412); the push rod (45) is hinged to the hair box (41), and its lower end is placed in the sliding channel; The drive mechanism (2) is adapted to drive the clamping mechanism (3) to drive the push block (44) to slide through the push rod (45) during the film launching action, so that the push block (44) pushes the new slide (101) located on the top layer in the receiving cavity, thereby causing the clamping part of the new slide (101) located on the top layer to pass through the film launching port (412) and be exposed outside the film launching box (41).

3. The paraffin slice processing apparatus according to claim 1, characterized in that, The receiving notch (61) is opened in the front-to-back direction and is located at the rear end of the mounting plate water tank (6); the receiving notch (61) is provided with a first water inlet (63) connected to the circulation mechanism (7). The drainage gap (62) is opened in the left and right direction and is located at the front end of the mounting plate water tank (6); the front end of the mounting plate water tank (6) is also provided with a second water inlet (64) connected to the circulation mechanism (7). The drainage notch (62) and the second water inlet (64) are respectively located at the left and right ends of the mounting plate water tank (6); The circulation mechanism (7) is adapted to inject water into the inner cavity of the mounting water tank (6) through the second water inlet (64) when the slicer (5) cuts the wax block; The circulation mechanism (7) is also adapted to inject water into the inner cavity of the mounting water tank (6) through the first water inlet (63) when the slicer (5) cuts out waste slices.

4. The paraffin slicing processing apparatus according to claim 1, characterized in that, A prying mechanism (8) is provided at the receiving notch (61). The paddle mechanism (8) includes a paddle lever (81), a motor (82), and a locking assembly (84). The lever (81) is rotatably mounted in the inner cavity of the mounting plate water tank (6) and positioned above the receiving notch (61); the lever (81) extends in the left-right direction; Both ends of the lever (81) extend outside the mounting plate water tank (6), one end of which is connected to the motor (82), and the other end is provided with a limiting ring groove (811) that engages with the locking assembly (84). The motor (82) is installed on the outer wall of the mounting tank (6) and is adapted to drive the middle protrusion of the lever (81) to move the sample slice (103) between the receiving notch (61) and the slicer (5). The locking assembly (84) is rotatably mounted on the outer wall of the mounting plate water tank (6).

5. The paraffin slice processing apparatus according to claim 1, characterized in that, The clamping mechanism (3) includes a fixed gripper (31) and a movable gripper (32); The fixed gripper (31) is connected to the output end of the drive mechanism (2) through the flip drive module (34), and the fixed gripper (31) is provided with a mating protrusion (35) suitable for cooperating with the push rod (45). The movable gripper (32) is connected to the fixed gripper (31) via the gripping drive module (33); The clamping drive module (33) is adapted to drive the movable jaw (32) and the fixed jaw (31) to clamp or release the glass slide.

6. The paraffin slice processing apparatus according to claim 1, characterized in that, A transition plate (52) is provided between the blade (51) of the slicer (5) and the receiving notch (61). The transition plate (52) is provided with an inclined transition surface (521), which is located between the bottom surface of the receiving notch (61) and the cutting edge of the blade (51). The top opening of the mounting water tank (6) is T-shaped, and the end of the mounting water tank (6) near the blade holder of the slicer (5) is provided with an arc-shaped clearance structure; The bottom surface of the receiving notch (61) includes a horizontal bottom surface near the discharge end of the slicer (5) and an arc-shaped bottom surface away from the discharge end of the slicer (5), and the arc-shaped bottom surface of the receiving notch (61) bends downward. The bottom surface of the drainage gap (62) is a horizontal bottom surface, and the horizontal bottom surface of the receiving gap (61) is higher than the horizontal bottom surface of the drainage gap (62).

7. The paraffin slice processing apparatus according to claim 1, characterized in that, The circulation mechanism (7) includes a water storage tank (71) and a filter screen (72); The inner cavity of the water storage tank (71) is connected to the inner cavity of the mounting plate water tank (6) through a water pump and pipeline. The water storage tank (71) is also suitable for receiving water discharged from the drainage gap (62). The filter screen (72) is detachably mounted on the water storage tank (71) and is suitable for filtering the water discharged from the drain opening (62).

8. The paraffin slice processing apparatus according to claim 1, characterized in that, The drive mechanism (2) includes a horizontal drive module (21), a vertical drive module (22), and a rotary drive module (23); The guide rail of the horizontal drive module (21) is mounted on the frame (1), and the slider of the horizontal drive module (21) is connected to the slider of the vertical drive module (22). The fixed end of the rotary drive module (23) is located at the lower end of the guide rail of the vertical drive module (22), and the output end of the rotary drive module (23) is connected to the clamping mechanism (3). The horizontal drive module (21) is adapted to drive the clamping mechanism (3) to move in the forward and backward direction; The output end of the rotary drive module (23) extends in the left-right direction.

9. The paraffin slicing apparatus according to claim 1, characterized in that, The film-making mechanism (4) and the sample box (9) are placed on top of the frame (1), and the mounting water tank (6) and the slicer (5) are placed below the frame (1); The mounting water tank (6), the film issuing mechanism (4), and the sample box (9) are arranged in sequence from front to back, and the slicer (5) is placed behind the mounting water tank (6); The frame (1) is provided with an opening for exposing the mounting plate water tank (6); The push rod (45) is located at the rear end of the film-generating mechanism (4).

10. A method for processing paraffin sections, characterized in that, The paraffin sectioning apparatus according to any one of claims 1 to 9 comprises the following steps: S1. Slide Removal Action: The drive mechanism (2) cooperates with the clamping mechanism (3). The clamping mechanism (3) clamps the new slide (101) whose clamping part is exposed outside the slide issuing mechanism (4) and pulls the new slide (101) out of the slide issuing mechanism (4). S2, Mounting action: Slicer (5) cuts wax block; When unusable scrap pieces are cut out, the circulation mechanism (7) injects water into the receiving notch (61) so that the scrap pieces falling into the receiving notch (61) are pushed by the water flow and discharged from the drainage notch (62) to the outside of the mounting water tank (6); When a usable sample slice (103) is cut out, the circulation mechanism (7) stops injecting water into the receiving notch (61). After the sample slice (103) falls into the receiving notch (61), the drive mechanism (2) drives the clamping mechanism (3) holding the new slide (101) to move to the receiving notch (61) so that the sample slice (103) at the receiving notch (61) is attached to the new slide (101) and is taken out of the water. The sample slice (103) is attached to the new slide (101) to form the sample slide (102). S3, Water-spinning action: The driving mechanism (2) drives the clamping mechanism (3) holding the sample slide (102) to move upward, and at the same time the driving mechanism (2) drives the clamping mechanism (3) to swing so that the water droplets attached to the sample slide (102) are flung off. After the water-spinning action is completed, the clamping mechanism (3) drives the clamping end of the clamping mechanism (3) to rotate the sample slide (102) so that the sample slice (103) on the sample slide (102) is placed facing upwards. S4. Slide feeding action: The drive mechanism (2) drives the clamping mechanism (3) holding the sample slide (102) to move from above the mounting water tank (6) to the push rod (45) and push the push rod (45). The pushed rod (45) is pushed to push the new slide (101) in the slide issuing mechanism (4) so ​​that the clamping part of the new slide (101) in the slide issuing mechanism (4) is exposed outside the slide issuing mechanism (4); S5, Slide placement action: The drive mechanism (2) drives the clamping mechanism (3) holding the sample slide (102) to separate from the push rod (45) and move to the top of the sample box (9); then the drive mechanism (2) drives the clamping mechanism (3) holding the sample slide (102) to insert the sample slide (102) into the sample box (9) so that the sample slice (103) on the sample slide (102) is placed facing upwards; After the sample slide (102) is inserted into the sample box (9), the clamping mechanism (3) releases the sample slide (102), the driving mechanism (2) drives the clamping mechanism (3) away from the sample box (9), and the clamping mechanism (3) drives the clamping end of the clamping mechanism (3) to reset and flip. When the clamping mechanism (3) separates from the push rod (45), the push rod (45) is reset by the action of the reset spring (47).

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