Qi and blood nourishing and anti-aging fermented traditional Chinese medicine compound as well as preparation process and application thereof

Abstract

The invention discloses a fermented traditional Chinese medicine compound capable of nourishing qi and blood and resisting aging, which is a composition of a fermented product and an edible carrier thereof, wherein the fermented product is obtained by carrying out composite enzymolysis treatment on traditional Chinese medicinal materials with the effects of tonifying qi, enriching blood and resisting aging and then carrying out composite strain fermentation on the treated traditional Chinese medicinal materials. Wherein the traditional Chinese medicinal materials at least comprise qi-tonifying traditional Chinese medicinal materials selected from ginseng, codonopsis pilosula, astragalus membranaceus, radix pseudostellariae, bighead atractylodes rhizome, poria cocos and liquorice; the blood-enriching traditional Chinese medicinal materials are selected from angelica sinensis, prepared rehmannia roots, radix paeoniae alba, donkey-hide gelatin, longan aril and mulberries; the anti-aging traditional Chinese medicinal materials are selected from fructus lycii, glossy privet fruit, dogwood, polygonum multiflorum, polygonatum kingianum, ginseng and acanthopanax senticosus.

Description

Technical Field

[0001] This application relates to the field of pharmaceutical products, specifically to a fermented traditional Chinese medicine compound that nourishes qi and blood and has anti-aging properties, as well as its preparation process and application. Background Technology

[0002] Adequate Qi and blood are the material basis for maintaining human life activities and health. Deficiency of Qi and blood easily leads to functional decline and is a significant internal factor accelerating the aging process. Traditional Chinese medicine theory has always emphasized strengthening the body's foundation and cultivating its vital energy by replenishing Qi and nourishing blood, thereby delaying aging. Herbs that replenish Qi, such as ginseng, astragalus, and codonopsis; herbs that replenish blood, such as angelica, rehmannia, and donkey-hide gelatin; and herbs that combine nourishing and antioxidant effects, such as wolfberry, polygonatum, and he shou wu, are widely used in traditional health preservation practices.

[0003] However, the traditional methods of applying these Chinese medicinal herbs (such as decoction, powdering, and infusion) have significant limitations. First, the plant cell wall, acting as a natural barrier, severely hinders the full dissolution of intracellular active ingredients (such as polysaccharides, saponins, and flavonoids). Second, the large molecules in these herbs, such as starch, protein, and pectin, are not only difficult for the human body to directly absorb and utilize, but may also affect the stability and taste of the preparation. Furthermore, traditional processing methods are insufficient in converting potentially harmful components in the herbs (such as the prototypes of certain aglycones) and make it difficult to generate new active metabolites. These factors collectively lead to the common problems of low bioavailability, slow onset of action, and unstable active ingredients in traditional Chinese medicine preparations. Summary of the Invention

[0004] The summary section of this application is intended to provide a brief overview of the concepts, which will be described in detail in the detailed description section below. This summary section is not intended to identify key or essential features of the claimed technical solutions, nor is it intended to limit the scope of the claimed technical solutions.

[0005] To address the technical problems mentioned in the background section, some embodiments of this application provide a fermented traditional Chinese medicine complex that nourishes qi and blood and combats aging. The fermented traditional Chinese medicine complex is a composition of fermentation products and their edible carriers obtained by treating traditional Chinese medicinal materials with qi-tonifying, blood-tonifying, and anti-aging effects through compound enzymatic hydrolysis and then fermenting them with compound microbial strains. The traditional Chinese medicinal materials include at least: qi-tonifying herbs selected from ginseng, codonopsis, astragalus, pseudostellaria, atractylodes, poria, and licorice; blood-tonifying herbs selected from angelica, rehmannia, white peony root, donkey-hide gelatin, longan pulp, and mulberry; and anti-aging herbs selected from wolfberry, privet fruit, cornus officinalis, polygonum multiflorum, polygonatum sibiricum, ginseng, and eleutherococcus senticosus.

[0006] A preparation process for the above-mentioned fermented traditional Chinese medicine complex that nourishes qi and blood and has anti-aging properties includes the following steps:

[0007] The Chinese medicinal materials with the effects of replenishing qi, replenishing blood, and anti-aging are cleaned, disinfected, and physically pulverized.

[0008] The prepared materials are subjected to heat treatment above the sterilization temperature threshold;

[0009] Add hot water, the Chinese medicinal herbs with qi-tonifying, blood-tonifying, and anti-aging effects, the preparation materials, the nutrient fortifier, and the compound enzyme reagent to a mixing container, and mix them evenly by stirring.

[0010] The fermentation products are subjected to ultra-high temperature instantaneous sterilization.

[0011] The composite strain was inoculated into the sterilized fermentation product.

[0012] Furthermore, the compound enzyme reagent includes cellulase, pectinase, amylase, and protease.

[0013] Furthermore, the ultra-high temperature instantaneous sterilization treatment of the fermentation products includes heating the fermentation products at a high temperature of 80°C for 15-30 minutes.

[0014] Furthermore, the compound microbial strain includes lactic acid bacteria, yeast, and bifidobacteria.

[0015] Furthermore, the nutritional fortifiers include vitamin C, vitamin E, zinc, selenium, and coenzyme Q10.

[0016] Furthermore, the stirring container includes: a stirring tank, a vertical feeding pipe and a horizontal feeding pipe that are interconnected in the stirring tank, and a pushing component disposed inside the horizontal feeding pipe; powdered compound enzyme reagent is placed in the vertical feeding pipe; the pushing component is used to push the compound enzyme reagent in the horizontal feeding pipe outward; the opening of the horizontal feeding pipe is located below the liquid surface in the stirring tank.

[0017] Furthermore, the feeding assembly includes a first pusher plate and a second pusher plate that can reciprocate along the axial direction of the transverse feeding pipe, the outer periphery of the first pusher plate and the second pusher plate sealingly abutting against the inner wall of the transverse feeding pipe; a first drive member and a second drive member arranged outside the transverse feeding pipe and respectively connected to the first pusher plate and the second pusher plate, the first drive member and the second drive member being used to drive the first pusher plate and the second pusher plate to reciprocate independently within the transverse feeding pipe.

[0018] Application of a fermented traditional Chinese medicine compound that nourishes qi and blood and has anti-aging properties in the preparation of health foods or medicines for improving symptoms of qi deficiency and blood deficiency.

[0019] Application of a fermented traditional Chinese medicine compound that nourishes qi and blood and has anti-aging properties in the preparation of health foods or drugs for slowing down aging and improving antioxidant capacity.

[0020] The beneficial effects of this application are as follows:

[0021] The process integrates "compound enzymatic hydrolysis" and "compound microbial fermentation" sequentially. Compound enzymes (such as cellulase, pectinase, and protease) first efficiently disrupt the cell walls of the medicinal materials, initially degrading large molecules such as polysaccharides and proteins into smaller fragments or monomers, providing a rich and easily usable high-quality substrate for subsequent microbial fermentation. Compound microbial strains (such as lactic acid bacteria and yeast) then ferment on this optimized substrate, further decomposing and transforming substances, and producing various beneficial metabolites (such as organic acids, amino acids, vitamins, and enzymes). Attached Figure Description

[0022] The accompanying drawings, which form part of this application, are used to provide a further understanding of the application and to make other features, objects, and advantages of the application more apparent. The illustrative embodiments and descriptions of this application are used to explain the application and do not constitute an undue limitation of the application.

[0023] Furthermore, throughout the accompanying drawings, the same or similar reference numerals denote the same or similar elements. It should be understood that the drawings are schematic, and the elements are not necessarily drawn to scale.

[0024] In the attached diagram: Figure 1 This is an overall schematic diagram based on an embodiment of this application; Figure 2 This is a structural schematic diagram as part of an embodiment, mainly showing an observation from another perspective. Figure 1 The structure; Figure 3 This is a structural schematic diagram of a part of the embodiment, mainly showing... Figure 1 sectional structure; Figure 4 yes Figure 3 Enlarged view of part A; Figure 5 yes Figure 3 Enlarged view of part B; Figure 6 This is a structural schematic diagram as part of an embodiment, mainly showing an observation from another perspective. Figure 3 The structure.

[0031] Figure label:

[0032] 1. Mixing tank;

[0033] 2. Mixing components;

[0034] 3. Vertical feeding pipe; 31. Feeding hopper;

[0035] 4. Horizontal feeding pipe; 41. Opening; 42. First horizontal feeding pipe; 43. Second horizontal feeding pipe;

[0036] 5. Pushing assembly; 51. First push plate; 511. Elastic protrusion; 52. Second push plate; 521. Groove;

[0037] 6. First driving component; 61. First electric push rod; 62. Connecting pipe; 63. Misaligned connecting plate;

[0038] 7. Second driving component; 71. Second electric push rod; 72. Connecting rod;

[0039] 8. Control valve;

[0040] 9. Pump body. Detailed Implementation

[0041] Embodiments of this disclosure will now be described in more detail with reference to the accompanying drawings. While some embodiments of this disclosure are shown in the drawings, it should be understood that this disclosure can be implemented in various forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided to provide a more thorough and complete understanding of this disclosure. It should be understood that the accompanying drawings and embodiments of this disclosure are for illustrative purposes only and are not intended to limit the scope of protection of this disclosure.

[0042] It should also be noted that, for ease of description, only the parts relevant to the invention are shown in the accompanying drawings. Unless otherwise specified, the embodiments and features described in this disclosure can be combined with each other.

[0043] It should be noted that the concepts of "first" and "second" mentioned in this disclosure are used only to distinguish different devices, modules or units, and are not used to limit the order of functions performed by these devices, modules or units or their interdependencies.

[0044] It should be noted that the terms "a" and "a plurality of" used in this disclosure are illustrative rather than restrictive, and those skilled in the art should understand that, unless otherwise expressly indicated in the context, they should be understood as "one or more".

[0045] This disclosure will now be described in detail with reference to the accompanying drawings and embodiments.

[0046] A fermented traditional Chinese medicine complex that nourishes qi and blood and has anti-aging properties, wherein the fermented traditional Chinese medicine complex is a composition of fermentation products obtained by compound enzymatic hydrolysis of traditional Chinese medicinal materials with qi-tonifying, blood-tonifying and anti-aging effects, followed by fermentation with compound microbial strains, and an edible carrier thereof.

[0047] in:

[0048] The medicinal materials mentioned include at least:

[0049] Qi-tonifying Chinese medicinal herbs: selected from ginseng, codonopsis, astragalus, pseudostellaria, atractylodes macrocephala, poria cocos, and licorice;

[0050] Blood-nourishing Chinese medicinal herbs: selected from Angelica sinensis, Rehmannia glutinosa, Paeonia lactiflora, donkey-hide gelatin, longan pulp, and mulberry;

[0051] Anti-aging Chinese medicinal herbs: selected from wolfberry, privet fruit, cornus officinalis, fleeceflower root, polygonatum rhizome, ginseng, and eleutherococcus senticosus.

[0052] Preferred ingredient ratio: Astragalus membranaceus 20g, Codonopsis pilosula 15g, Angelica sinensis 10g, Rehmannia glutinosa 10g, Lycium barbarum 20g, Polygonatum sibiricum 15g, and Longan aril 10g.

[0053] The preparation process of a fermented traditional Chinese medicine compound that nourishes qi and blood and has anti-aging effects includes:

[0054] Pre-treatment: After cleaning and ultraviolet disinfection, the above-mentioned medicinal materials are pulverized and passed through a 60-mesh sieve.

[0055] Preparation and enzymatic hydrolysis: Add 2L of purified water (80℃) to a stirred tank, add the herbal powder, then add 5g of fructooligosaccharide (nutrient fortifier) ​​and 0.5g of compound enzyme reagent (cellulase:pectinase:protease = 2:1:1). Stir and enzymatically hydrolyze at 50℃ for 2 hours.

[0056] Sterilization and inoculation: Sterilize the enzymatic hydrolysate at 95℃ for 15 minutes and cool to 37℃. Inoculate with a compound microbial fermentation agent (Lactobacillus plantarum:Streptococcus thermophilus:Saccharomyces cerevisiae = 5:3:2) at an inoculation rate of 3%.

[0057] Fermentation: Ferment at a constant temperature of 37℃ for 48 hours.

[0058] Post-processing and sterilization: After fermentation, the fermentation broth is homogenized, subjected to ultra-high temperature instantaneous sterilization (80℃, 20 minutes), and bottled to obtain the fermented Chinese medicine compound oral liquid.

[0059] Comparative Example 1: Traditional Water-boiling Process

[0060] Take the same amount of the same Chinese medicinal materials as in Example 1, add 10 times the amount of water, soak for 30 minutes, decoct twice, combine the filtrates, and concentrate to a volume similar to the final product of Example 1. No enzymatic hydrolysis or fermentation treatment is required.

[0061] Comparative Example 2, single enzymatic hydrolysis treatment

[0062] The preparation process is basically the same as in Example 1, but inoculation fermentation is not performed in step 4. That is, after sterilizing the enzymatic hydrolysate, subsequent homogenization and sterilization bottling are carried out directly.

[0063] Comparative Example 3, Single Fermentation Treatment

[0064] The preparation process is basically the same as in Example 1, but the complex enzymatic hydrolysis process in step 3 is omitted. Instead, the herbal powder is mixed with hot water and a nutrient fortifier, then directly sterilized in step 4, and finally inoculated with the same strain for fermentation.

[0065] The products obtained in Example 1 and Comparative Examples 1-3 were tested for multiple key indicators, and the results are shown in the table below:

[0066] Testing items Example 1 (Combined Enzymatic Hydrolysis + Fermentation) Comparative Example 1 (Traditional Decoction) Comparative Example 2 (Single Enzyme Digestion) Comparative Example 3 (Single Fermentation) Polysaccharide content (mg / mL) 25.4 ± 1.2 8.7 ± 0.5 18.6 ± 0.9 15.3 ± 0.8 Total saponin content (mg / mL) 1.85 ± 0.10 0.62 ± 0.05 1.20 ± 0.08 1.05 ± 0.07 Total flavonoid content (mg / mL) 0.98 ± 0.05 0.35 ± 0.03 0.70 ± 0.04 0.59 ± 0.04 DPPH free radical scavenging rate (%) 92.5 ± 2.1 48.3 ± 3.0 75.6 ± 2.5 68.4 ± 2.8 ABTS⁺ free radical scavenging rate (%) 89.8 ± 1.8 41.2 ± 2.7 72.1 ± 2.2 65.3 ± 2.5 Soluble solids increase rate (%) 185 100 142 131 Total essential amino acids (mg / mL) 3.42 ± 0.15 1.05 ± 0.08 2.21 ± 0.12 2.88 ± 0.13 Animal experiments: Hemoglobin elevation rate +18.7% +8.2% +12.5% +14.1% Animal experiments: Increased serum SOD activity +22.3% +9.5% +15.6% +17.0%

[0067] Free radical scavenging rate is used to evaluate in vitro antioxidant (anti-aging) capabilities.

[0068] The increase in soluble solids was based on Comparative Example 1 (100%), representing the degree of increase in total extractable substances. Animal experiments were conducted using mice with a qi and blood deficiency model, who were treated with an equal amount of the drug product for 4 weeks before the results were evaluated.

[0069] In summary, compared with the comparative example, Example 1 showed a multiple-fold increase in the content of various active ingredients, in vitro antioxidant activity, and efficacy indicators in animal experiments. This fully demonstrates that the compound enzymatic hydrolysis and fermentation process can greatly break down cell walls, release and transform the effective substances in medicinal materials, and significantly improve the efficacy of the product.

[0070] Compared with Comparative Example 2 or Comparative Example 3, the product of this invention significantly outperforms any single treatment process in all key indicators. This indicates a significant synergistic effect between enzymatic hydrolysis and fermentation: the combined enzymatic hydrolysis provides a richer and more readily available substrate for subsequent microbial fermentation; while the fermentation process not only further decomposes substances but also produces new active ingredients (such as higher levels of certain essential amino acids after fermentation) and flavor compounds. This synergistic effect is key to achieving efficient biotransformation.

[0071] This invention, through an integrated process of "compound enzymatic hydrolysis-compound microbial fermentation," not only significantly increases the concentration and bioactivity of the core components for nourishing qi and blood and anti-aging in the product, but also enriches the product's nutritional spectrum through microbial metabolism, improving the absorption and utilization rate and potential taste of traditional Chinese medicine preparations. The tabular data systematically demonstrates the comprehensive advantages of this invention in terms of both process and product efficacy.

[0072] The aforementioned fermented Chinese herbal medicine complexes that nourish qi and blood and have anti-aging properties can be used in the preparation of health foods or medicines to improve symptoms of qi deficiency and blood deficiency.

[0073] The aforementioned fermented Chinese herbal medicine complexes that nourish qi and blood and have anti-aging properties can be used in the preparation of health foods or drugs to slow down aging and improve antioxidant capacity.

[0074] Reference Figure 1-6 ,

[0075] In some embodiments, the stirring container includes a stirring tank 1, which has a conventional structure and contains liquid to be enzymatically hydrolyzed or otherwise processed. The top of the tank may be an open structure or have an openable lid. Inside the stirring tank 1, a stirring component 2 is provided, such as a stirring rod, stirring paddle, or other stirring impeller assembly. The stirring component 2 can rotate around the axis of the tank under the drive of a drive motor to stir and mix the liquid inside the tank.

[0076] Since the medicinal powder and powdered enzyme preparation need to be added to the mixing tank 1 and quickly dispersed and dissolved by the stirring action of the stirring paddle, if the traditional method of adding materials directly to the liquid surface from top to bottom is used, it is easy to cause problems such as powder splashing, dust pollution, uneven addition, and local agglomeration. At the same time, some powder will adhere to the tank wall or surface to form clumps, affecting enzyme activity and fermentation effect.

[0077] To address the aforementioned issues, the mixing container also includes a vertical feeding pipe 3 and a horizontal feeding pipe 4 positioned below the liquid surface. These allow the powder to be discharged directly from the interior of the liquid, where it is subjected to the stirring flow field near the discharge point, thus rapidly dispersing it within the liquid. Simultaneously, the pusher assembly 5 with its specific structure and driving mechanism effectively prevents external liquid from flowing back into the vertical feeding pipe 3, thus avoiding the powder from clumping, adhering, and deteriorating when it encounters water inside the pipe.

[0078] The lower end of the vertical feeding pipe 3 extends into the interior of the mixing tank 1, and is preferably positioned at a certain depth below the liquid surface, for example, 50–300 mm below the liquid surface, to ensure that the powder is completely submerged in liquid when it is finally discharged from the horizontal pipe. The upper end of the vertical feeding pipe 3 is located outside the mixing tank 1, and can pass through the tank wall or through a pre-drilled hole in the tank cover to connect with an external feeding system. Alternatively, the vertical feeding pipe 3 can be located outside the mixing tank 1, and the horizontal feeding pipe 4 can penetrate the mixing tank 1, such that the opening 41 of the horizontal feeding pipe 4 is below the liquid surface in the mixing tank 1.

[0079] A feeding hopper 31 is provided at the upper end of the vertical feeding pipe 3. The feeding hopper 31 is used to receive powdered enzyme preparations delivered manually or by a higher conveying device, so that the powder falls into the vertical feeding pipe 3 under the action of gravity.

[0080] The lower end of the vertical feeding pipe 3 is connected to the horizontal feeding pipe 4 through two pipe fittings. The horizontal feeding pipe 4 is arranged in a horizontal or near-horizontal direction, located below the liquid surface, and preferably arranged in the outer edge area of ​​the stirring member 2 or near its sweeping trajectory, that is, the opening 41 area of ​​the horizontal feeding pipe 4 is close to the high shear zone or strong convection zone of the stirring paddle, so that the powder is quickly entrained and uniformly mixed after being discharged.

[0081] The end of the horizontal feeding pipe 4 away from the vertical feeding pipe 3 is provided with an opening 41 that communicates with the liquid. The opening 41 can be the port of the horizontal feeding pipe 4, or multiple discharge holes opened circumferentially at the end, or even a grooved structure can be set along the pipe wall to ensure that the powder is pushed into the liquid smoothly after being pushed into this area.

[0082] The transverse feeding tube 4 is internally equipped with a pushing assembly 5. The pushing assembly 5 includes: a first pushing plate 51, a second pushing plate 52, a first driving member 6 for driving the first pushing plate 51 to move, and a second driving member 7 for driving the second pushing plate 52 to move.

[0083] Both the first pusher plate 51 and the second pusher plate 52 can reciprocate along the axis of the transverse feeding pipe 4. Preferably, the first pusher plate 51 and the second pusher plate 52 are basically disc-shaped, and a sealing fit structure is provided between their outer periphery and the inner wall of the transverse feeding pipe 4. For example, an elastic sealing ring or sealing lip is provided on the outer edge of the pusher plate, so that a sliding sealing fit is formed between the pusher plate and the pipe wall. On the one hand, the first pusher plate 51 can effectively push the powder in front during its forward stroke; on the other hand, the first pusher plate 51 can prevent external liquid from entering the area behind the pusher plate during its backward stroke, preventing liquid from flowing back into the vertical feeding pipe 3 through the transverse feeding pipe 4.

[0084] The first driving component 6 includes a first electric push rod 61, a connecting pipe 62, and a misaligned connecting plate 63. The second driving component 7 includes a second electric push rod 71 and a connecting rod 72.

[0085] One end of the connecting pipe 62 is fixedly connected to the first push plate 51, and the other end extends out of the transverse feeding pipe 4 and is fixedly connected to the misaligned connecting plate 63. The misaligned connecting plate 63 is connected to the output end of the first electric push rod 61, so that when the first electric push rod 61 extends or retracts, the connecting pipe 62 is driven to move axially through the misaligned connecting plate 63, thereby driving the first push plate 51 to reciprocate within the transverse feeding pipe 4. The connecting rod 72 is fixedly connected to the second push plate 52, and passes axially through the through hole on the first push plate 51 and through the connecting pipe 62 to extend out of the transverse feeding pipe 4, connecting to the second electric push rod 71. The second electric push rod 71 is also arranged transversely, and its output end is connected to the connecting rod 72. Axial extension or retraction can drive the second push plate 52 to move along the transverse feeding pipe 4. To accommodate two electric actuators within a limited space and prevent their installation positions from interfering with each other, a misaligned connecting plate 63 is provided to misalign the axes of the first electric actuator 61 and the connecting pipe 62, thereby reserving space near the end of the connecting pipe 62 to accommodate the second electric actuator 71.

[0086] To prevent liquid from seeping into the area behind the first push plate 51 through the through hole, an elastic seal, such as a rubber plug, rubber ring, or elastic sealing sleeve, is provided between the through hole and the connecting rod 72. This elastic seal is preferably clamped or fixed to the wall of the through hole, forming an annular sealing contact with the connecting rod 72. This effectively prevents liquid from leaking along the through hole to the rear side of the first push plate 51 without affecting the reciprocating linear movement of the connecting rod 72.

[0087] A control valve 8 is provided on the vertical feeding pipe 3, preferably above its position near the connection point with the horizontal feeding pipe 4. The control valve 8 can be a conventional pipeline shut-off valve, ball valve, butterfly valve, or electric / pneumatic control valve 8, used to selectively cut off or open the flow channel of powder in the vertical feeding pipe 3 to the downstream horizontal feeding pipe 4.

[0088] The work process is as follows:

[0089] In the initial state, the first push plate 51 and the second push plate 52 are attached together and are located on the outer side of the transverse feeding pipe 4, preferably close to the opening 41, so as to ensure that there is as little residual powder inside the transverse feeding pipe 4 as possible after the previous feeding cycle is completed, and to form a reliable isolation from the external liquid.

[0090] The system controls the first electric push rod 61 and the second electric push rod 71 to move, keeping the second push plate 52 in contact with the first push plate 51. Then, the first push plate 51 moves backward toward the end of the horizontal feeding pipe 4 that connects to the vertical feeding pipe 3, until the first push plate 51 moves to the predetermined "feeding position". At this position, the first push plate 51 is at least partially located below or behind the area where the vertical feeding pipe 3 and the horizontal feeding pipe 4 connect, so that a space sufficient to accommodate the powder is formed in front of the first push plate 51.

[0091] The control valve 8 is opened, causing the powdered enzyme preparation accumulated above the control valve 8 in the vertical feeding pipe 3 to fall into the horizontal feeding pipe 4 under gravity and accumulate in the area in front of the first push plate 51. At this time, since the first push plate 51 and the second push plate 52 are still close to each other or maintain a certain distance, and the second push plate 52 is still located in front of the first push plate 51, the space in front of it is still sealed, and the powder only accumulates in the area between the first push plate 51 and the connection port of the control valve 8.

[0092] Once the predetermined amount of powder has fallen from the vertical feeding pipe 3 into the horizontal feeding pipe 4, the control valve 8 is closed to prevent new powder from continuing to fall.

[0093] Drive the first electric push rod 61 to move the first push plate 51 toward the opening 41, pushing the powder material piled up in front of it to move along the transverse feeding pipe 4. When the powder is completely squeezed and piled between the first push plate 51 and the second push plate 52, the second push plate 52 moves forward to open the opening 41 and pushes the powder out from the opening 41 and directly into the liquid.

[0094] After the powder is completely discharged, the second pusher plate 52 retracts and returns to a position where it is in contact with the first pusher plate 51. At this point, the two pushers form a tightly fitted double-pusher sealing structure within the transverse feeding pipe 4. Subsequently, the control system drives the first pusher plate 51 and the second pusher plate 52 to retract together in the direction communicating with the vertical feeding pipe 3, returning to their initial positions. Because the first pusher plate 51 and the second pusher plate 52 remain in contact or nearly in contact throughout the retraction process, the cross-section of the transverse feeding pipe 4 is sealed, and the external liquid is blocked outside the opening 41, thus preventing it from flowing further into the vertical feeding pipe 3 through the transverse feeding pipe 4.

[0095] Through the reciprocating motion and valve control described above, this embodiment can ensure that the inside of the vertical feeding pipe 3 remains dry for a long time, and the powdered enzyme preparation does not come into contact with the liquid inside the vertical feeding pipe 3, thus avoiding moisture deterioration or scaling after prolonged stay; at the same time, the powder is directly added below the liquid surface from the opening 41 of the horizontal feeding pipe 4 and is within the stirring flow field, which is conducive to the rapid dispersion, dissolution and uniform mixing of the powder.

[0096] In another embodiment, the horizontal feeding pipe 4 includes a first horizontal feeding pipe 424a and a second horizontal feeding pipe 434b. The lower end of the vertical feeding pipe 3 is connected to a tee fitting, and the first horizontal feeding pipe 424a and the second horizontal feeding pipe 434b are respectively connected to the other two interfaces of the tee fitting, thereby realizing a "tee connection" between the vertical and two horizontal pipes.

[0097] In this embodiment, the first pusher plate 51 can move within the first transverse feeding pipe 424a, and can also pass through the tee fitting and continue to reciprocate into the second transverse feeding pipe 434b. The control system sets the retraction endpoint position of the first pusher plate 51 so that when the control valve 8 is opened, it can retract to the rear of the position where the vertical feeding pipe 3 connects with the tee fitting, that is, inside the second transverse feeding pipe 434b, so that the space in front of the first pusher plate 51 includes the inner cavity of the tee fitting and at least part of the inner cavity of the second transverse feeding pipe 434b, forming a larger volume material receiving space.

[0098] In other embodiments, the first push plate 51 has an axially projecting elastic protrusion 511 on its end face facing the second push plate 52, and the second push plate 52 has a groove 521 on its end face facing the first push plate 51 to accommodate the elastic protrusion 511. The elastic protrusion 511 can be made of an elastic material, such as rubber, silicone, or elastic plastic, or other non-absorbent materials, or it can be a composite structure of a rigid substrate covered with an elastic layer. The groove 521 can be directly machined into the body material of the second push plate 52, or it can be provided as an insert.

[0099] The solid volume of the protrusion is larger than the effective volume of the groove 521, so that when the second push plate 52 moves closer to the first push plate 51, the protrusion is inserted into the groove 521 and undergoes a certain elastic deformation, so as to completely squeeze out any residual liquid or trace powder mixture that may exist inside the groove 521. When the end faces of the two push plates are completely attached, there is almost no residual moisture left on the joint surface between the push plates.

[0100] In other embodiments, the second electric push rod 71 and the connecting rod 72 can also be connected by a staggered connection, with the end of the connecting rod 72 being left unobstructed. In this embodiment, an air injection chamber is formed in the connecting rod 72, and an air pump is provided at the end of the connecting rod 72. The air pump injects external air into the mixing tank 1, or injects inert gas into the mixing tank 1. By utilizing the formation of air bubbles in the liquid, the powder can be quickly dispersed into the liquid in the mixing tank 1.

[0101] In other embodiments, the protrusion is made of an elastic rubber membrane, which forms a pouch. The pouch is connected to the external pump body 9 via a hose. The external pump body 9 is connected to hot air or has a built-in air heating structure, injecting air into the elastic rubber membrane to increase and decrease the volume of the protrusion. This can be achieved by the protrusion initially contacting the groove 521 with a very small volume, then gradually increasing in volume, so that the protrusion initially contacts the middle of the groove 521, and then gradually contacts other parts of the groove 521, gradually squeezing the water out of the groove 521. Then, the first push plate 51 and the second push plate 52 move closer to each other, and the volume of the protrusion slowly decreases until the first push plate 51 and the second push plate 52 are pressed together.

[0102] The above embodiments use the first electric actuator 61 and the second electric actuator 71 as driving components. In practical applications, the first driving component 6 and / or the second driving component 7 can also be implemented using a cylinder, a hydraulic cylinder, a lead screw motor, a linear servo mechanism, or a combination thereof.

[0103] The above description is merely a selection of preferred embodiments of this disclosure and an explanation of the technical principles employed. Those skilled in the art should understand that the scope of the invention involved in the embodiments of this disclosure is not limited to technical solutions formed by specific combinations of the above-described technical features, but should also cover other technical solutions formed by arbitrary combinations of the above-described technical features or their equivalents without departing from the above-described inventive concept. For example, technical solutions formed by substituting the above-described features with (but not limited to) technical features with similar functions disclosed in the embodiments of this disclosure.

Claims

1. A fermented traditional Chinese medicine complex that nourishes qi and blood and has anti-aging properties, characterized in that: The fermented Chinese herbal medicine complex is a combination of fermentation products and its edible carrier obtained by compound enzymatic hydrolysis and then fermentation with compound microbial strains of Chinese herbal medicines with qi-tonifying, blood-tonifying and anti-aging effects. in: The medicinal materials mentioned include at least: Qi-tonifying Chinese medicinal herbs: selected from ginseng, codonopsis, astragalus, pseudostellaria, atractylodes macrocephala, poria cocos, and licorice; Blood-nourishing Chinese medicinal herbs: selected from Angelica sinensis, Rehmannia glutinosa, Paeonia lactiflora, donkey-hide gelatin, longan pulp, and mulberry; Anti-aging Chinese medicinal herbs: selected from wolfberry, privet fruit, cornus officinalis, fleeceflower root, polygonatum rhizome, ginseng, and eleutherococcus senticosus.

2. A preparation process for a fermented traditional Chinese medicine complex for nourishing qi and blood and anti-aging as described in claim 1, characterized in that, Includes the following steps: The Chinese medicinal materials with the effects of replenishing qi, replenishing blood, and anti-aging are cleaned, disinfected, and physically pulverized. The prepared materials are subjected to heat treatment above the sterilization temperature threshold; Add hot water, the Chinese medicinal herbs with qi-tonifying, blood-tonifying, and anti-aging effects, the preparation materials, the nutrient fortifier, and the compound enzyme reagent to a mixing container, and mix them evenly by stirring. The fermentation products are subjected to ultra-high temperature instantaneous sterilization. The composite strain was inoculated into the sterilized fermentation product.

3. The preparation process according to claim 2, characterized in that, The compound enzyme reagent includes cellulase, pectinase, amylase, and protease.

4. The fermentation process according to claim 2, characterized in that, Ultra-high temperature instantaneous sterilization of fermentation products includes heating the fermentation products at 80°C for 15-30 minutes.

5. The preparation process according to claim 2, characterized in that, The compound microbial strain includes lactic acid bacteria, yeast, and bifidobacteria.

6. The preparation process according to claim 2, characterized in that, The nutritional fortifiers include vitamin C, vitamin E, zinc, selenium, and coenzyme Q10.

7. The preparation process according to claim 2, characterized in that, The mixing container includes: a mixing tank, a vertical feeding pipe and a horizontal feeding pipe that are interconnected in the mixing tank, and a pushing component disposed inside the horizontal feeding pipe; Powdered compound enzyme reagent is placed in the vertical feeding tube; The pusher assembly is used to push the compound enzyme reagent in the horizontal feeding tube outward; The opening of the horizontal feeding pipe is located below the liquid level in the mixing tank.

8. The preparation process according to claim 7, characterized in that, The feeding assembly includes a first pusher plate and a second pusher plate that can reciprocate along the axial direction of the transverse feeding pipe, and the outer periphery of the first pusher plate and the second pusher plate are in sealed contact with the inner wall of the transverse feeding pipe. A first driving member and a second driving member are arranged outside the transverse feeding tube and connected to the first push plate and the second push plate, respectively. The first driving member and the second driving member are respectively used to drive the first push plate and the second push plate to reciprocate independently within the transverse feeding tube.

9. The application of the fermented traditional Chinese medicine complex according to claim 1 in the preparation of health food or medicine for improving symptoms of qi deficiency and blood deficiency.

10. The application of the fermented traditional Chinese medicine complex according to claim 1 in the preparation of health foods or drugs for slowing down aging and improving antioxidant capacity.

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