Directional liquid drug delivery device

Abstract

The utility model discloses a directional liquid medicine guide device includes controller and medicine liquid guide component, and the controller includes box body, sets up the main control circuit board in the box body inside and two current output interfaces of electric connection in the main control circuit board, and medicine liquid guide component includes main electrode part and auxiliary electrode part, and the main electrode part includes the main casing with medicine liquid storage compartment and electrode storage compartment, and the main electrode board is placed in the electrode storage compartment, and the semi-permeable membrane and the gasket, and the main casing is set up with medicine liquid storage compartment the medicine liquid permeation hole of intercommunication and is used for the medicine liquid mouth of injection or drawing out medicine liquid, and the auxiliary electrode part includes the auxiliary casing and sets up the auxiliary electrode board in the auxiliary casing, and the main casing and auxiliary casing are connected through the bandage and enclose the wearing space, and the main electrode board and auxiliary electrode board are connected with two current output interfaces through the power cord, and this directional liquid medicine guide device can satisfy the local liquid medicine delivery requirement, and the absorption rate of medicine is improved obviously, and the equipment use has the flexibility, the repeatability and the security.

Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, and more specifically, it relates to a directional liquid drug delivery device. Background Technology

[0002] In clinical practice, local tissue or organ injuries or lesions are frequently encountered, often requiring topical medication. However, the skin's barrier function and the low extravascular absorption of these medications significantly reduce their effectiveness. Therefore, improving the absorption efficiency of topical medications has always been a challenging problem in medical technology.

[0003] Direct current drug delivery therapy offers unique advantages over traditional drug administration methods (including oral and injection methods), improving the absorption efficiency of locally applied medications. Direct current drug delivery therapy refers to the use of direct current to introduce drug ions into the body through the skin, mucous membranes, or wounds for treatment. The principle is that in a drug solution, some drugs dissociate into ions. Under the influence of direct current, anions and cations move in a specific direction. If the cathode liner contains negatively charged drug ions, or the anode liner contains positively charged drug ions, due to the principle of like charges repelling and unlike charges attracting, the charged drug ions will move in the opposite direction and enter the body after current is applied. Therefore, cationic drugs can only be delivered from the anode, and anionic drugs can only be delivered from the cathode. Furthermore, electroosmosis further promotes the transport of neutral molecules, especially when the skin is negatively charged, in which case the direction of electroosmosis is consistent with the current (from anode to cathode).

[0004] The main characteristics of direct current iontophoresis for drug delivery are: 1) Drug ions can be directly introduced into relatively superficial lesions, resulting in a higher concentration in local superficial tissues. Furthermore, because the local concentration of drug ions is higher than the concentration reached after systemic administration, the duration of action is longer. Moreover, drug ions introduced via direct current form an "ion pool" locally, unlike other methods of drug administration which are quickly excreted through blood circulation. Therefore, the introduced drug ions are stored in the body for a longer period, resulting in a longer therapeutic effect. 2) Direct current iontophoresis for drug delivery delivers drugs externally, avoiding gastrointestinal irritation or systemic side effects associated with oral or injectable medications. 3) In addition to the effects of the drug itself, direct current iontophoresis for drug delivery also has the effect of altering the permeability of the stratum corneum, allowing drug ions to directly enter the interstitial spaces or body fluid circulation. Therefore, the two enhance each other, resulting in a better therapeutic effect than drugs or direct current alone. Thus, direct current iontophoresis for drug delivery can enhance drug absorption and efficacy.

[0005] Currently, the treatment process using direct current drug iontophoresis typically involves the use of a controller, electrode pads, wires, gauze, padding, and fixation straps. Before treatment, the gauze is soaked in a drug solution and placed on the skin at the treatment site. The padding and electrodes are then placed on top and secured with the fixation straps. The electrode pads are connected to the controller via wires, and treatment is initiated after electricity is applied.

[0006] The current method of directly soaking gauze in the medicine solution and placing it on the skin, then introducing the medicine through electrode pads, is prone to causing skin burns due to the generation of acid and alkali byproducts from electrolysis, resulting in low safety.

[0007] Therefore, making devices that improve local drug absorption efficiency safer is a pressing technical issue in the industry. Utility Model Content

[0008] The purpose of this invention is to propose a directional liquid drug delivery device to solve the problem of low safety in the existing technology.

[0009] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0010] This utility model proposes a directional liquid drug delivery device, including a controller and a drug delivery component. The controller includes a housing, a main control circuit board disposed inside the housing, and two current output interfaces electrically connected to the main control circuit board and exposed outside the housing. The drug delivery component includes a main electrode component and a secondary electrode component. The main electrode component includes a main shell having a drug storage chamber and an electrode storage chamber, a main electrode plate placed inside the electrode storage chamber, a semi-permeable membrane, and a liner. The main shell has a drug permeation hole communicating with the drug storage chamber and a drug port for injecting or extracting the drug. The liner is disposed on the side of the main shell with the drug permeation hole. The semi-permeable membrane is located between the main shell and the liner. The secondary electrode component includes a secondary shell and a secondary electrode plate disposed inside the secondary shell. The main shell and the secondary shell are connected by straps and form a wearable space. The main electrode plate and the secondary electrode plate are connected to the two current output interfaces by power lines.

[0011] Furthermore, the controller also includes two current direction switching buttons electrically connected to the main control circuit board and exposed outside the housing, and a current intensity adjustment button. The two current direction switching buttons include a main electrode positive power button for controlling the main electrode plate to be positively charged and a main electrode negative power button for controlling the main electrode plate to be negatively charged.

[0012] Furthermore, the main housing is also provided with a main electrode replacement port that communicates with the electrode storage compartment. The main electrode replacement port is used to replace different types of main electrode plates, including polar electrode plates or non-polar electrode plates.

[0013] Furthermore, two snap-fits are provided at intervals on the main housing, and the liner is snapped into the main housing through the two snap-fits to make the liner replaceable.

[0014] Furthermore, the main casing shares the same liquid inlet and outlet.

[0015] Furthermore, the secondary housing has a secondary electrode replacement port for replacing the secondary electrode plate. The secondary electrode replacement port is covered with a velvet cloth, and the end of the strap near the secondary housing has a Velcro strap for adjusting the length and securing the secondary housing.

[0016] Furthermore, the main casing and the secondary casing are made of waterproof and insulating materials.

[0017] Furthermore, the directional liquid drug delivery device is a specialized instrument for the directional delivery of liquid drugs used in local treatment.

[0018] Compared with the prior art, the directional liquid drug delivery device proposed in this utility model has at least one of the following beneficial effects:

[0019] 1. This invention allows for the direct use of liquid medications and enables the replacement of other medications, making it more flexible. At the same time, it effectively avoids skin burns that may occur due to the generation of acid and alkali byproducts at the electrode plates during electrolysis, making it safer.

[0020] 2. This invention can switch the positive / negative charge of the main electrode plate to adapt to drug solutions of different polarities.

[0021] 3. This utility model allows for the replacement of the main electrode plate type (polar / non-polar electrode), making it suitable for different types of drug solutions to prevent electrolysis products from damaging the drug solution's activity. Attached Figure Description

[0022] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0023] Figure 1 This is a schematic diagram of the directional liquid drug delivery device in Embodiment 1 of this utility model;

[0024] Figure 2 This is a schematic diagram of the structure of the medicine liquid introduction component in Embodiment 1 of this utility model;

[0025] Figure 3 This is a schematic diagram of the main electrode component in Embodiment 1 of this utility model;

[0026] Figure 4for Figure 3 Enlarged view of point A in the middle;

[0027] Figure 5 This is a schematic diagram of the directional liquid drug delivery device in Embodiment 2 of this utility model;

[0028] Figure 6 This is a schematic diagram of the directional liquid drug delivery device in Embodiment 3 of this utility model;

[0029] Figure 7 This is a schematic diagram of the structure of the medicine infusion component in Embodiment 3 of this utility model;

[0030] The main markings in the attached figures are as follows:

[0031] 11. Box body; 12. Current output interface; 13. Main electrode positive button; 14. Main electrode negative button; 15. Current intensity adjustment button; 16. Power switch button; 17. Display screen; 2. Main electrode component; 20. Main housing; 21. Medicine storage chamber; 22. Electrode storage chamber; 23. Main electrode plate; 24. Medicine penetration hole; 25. Padding; 26. Semi-permeable membrane; 27. Buckle; 28. Medicine port; 29. ​​Main electrode replacement port; 210. First power cord interface; 3. Secondary electrode component; 31. Secondary housing; 32. Secondary electrode plate; 33. Flannel cloth; 34. Secondary power cord interface; 4. Power cord; 5. Strap; 51. Velcro. Detailed Implementation

[0032] To make the technical problems, technical solutions, and beneficial effects of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0033] The directional liquid drug delivery device proposed in this invention can meet the requirements of local liquid drug delivery, significantly improve the drug absorption rate, and the device is flexible, repeatable and safe to use.

[0034] Example 1

[0035] Please refer to the following: Figures 1 to 4 The directional liquid drug delivery device proposed in this utility model includes two parts: a controller and a drug delivery component.

[0036] The controller includes a housing 11, a main control circuit board, two current output interfaces 12, a power switch button 16, a current intensity adjustment button 15, and a display screen 17. The main control circuit board is located inside the housing 11. The two current output interfaces 12 are electrically connected to the main control circuit board and are exposed at the bottom of the housing 11. The power switch button 16, the current intensity adjustment button 15, and the display screen 17 are electrically connected to the main control circuit board and are exposed at the front of the housing 11.

[0037] The drug delivery assembly includes a main electrode component 2 and a secondary electrode component 3. The main electrode component 2 and the secondary electrode component 3 are connected to two current output interfaces 12 on the controller via power lines 4. The main electrode component 2 includes a main housing 20, a main electrode plate 23, a semi-permeable membrane 26, and a pad 25. The main housing 20 contains a drug storage chamber 21 and an electrode storage chamber 22. The main housing 20 has a drug outlet 28 and a drug permeation hole 24 communicating with the drug storage chamber 21. The pad 25 is disposed on the side of the main housing 20 with the drug permeation hole 24. The semi-permeable membrane 26 is located between the main housing 20 and the pad 25. The secondary electrode component 3 includes a secondary housing 31 and a secondary electrode plate 32 disposed within the secondary housing 31. Furthermore, the main housing 20 of the main electrode component 2 and the secondary housing 31 of the secondary electrode component 3 are connected by straps 5 to form a wearable space.

[0038] In this embodiment, the main housing 20 includes a top wall and a bottom wall. The top wall of the main housing 20 has a liquid inlet 28 and a left-hand flap for covering the liquid inlet 28. The liquid inlet 28 serves as both an inlet and an outlet, improving space utilization and ease of use. The bottom wall of the main housing 20 has multiple liquid permeation holes 24 spaced apart. A semi-permeable membrane 26 is attached to the bottom wall of the main housing 20, and a pad 25 is snap-fitted to the bottom wall of the main housing 20. Two clips 27 are provided at both ends of the bottom wall of the main housing 20 for snapping the pad 25, thus securing the pad 25 to the bottom wall of the main housing 20 via the two clips 27. Of course, in other embodiments, a liquid inlet 28 may be provided at a certain position on the side wall of the main housing 20. A control valve for controlling the opening and closing of the liquid inlet 28 may be provided instead of the left flip cover. Two liquid inlets 28 may be provided, i.e., the inlet and outlet are set separately. Alternatively, a padding 25 may be used to fix the bottom wall of the main housing 20 with a bandage.

[0039] It should be noted that the semi-permeable membrane 26 can selectively allow components in the drug solution to pass through based on its pore size and membrane material characteristics, thus achieving a filtering effect. The liner 25 allows the drug solution ions filtered by the semi-permeable membrane 26 to be more evenly distributed on the skin surface, and the liner 25 also acts as a buffer, reducing skin irritation. In this embodiment, the semi-permeable membrane 26 and the liner 25 are stacked on the bottom wall of the main housing 20 for easy replacement of the semi-permeable membrane 26 and the liner 25. When selecting the semi-permeable membrane 26, the most suitable semi-permeable membrane 26 can be selected according to the diameter and type of drug ions. For example, the semi-permeable membrane 26 can be an ion exchange membrane, which is a polymer membrane containing ionic groups and having selective permeability to ions in a solution. Ion exchange membranes are made of special polymer materials. Because its ion-selective permeability is generally utilized in applications, it is also called an ion-selective permeable membrane. Based on the type of ions that selectively permeate, ion exchange membranes are divided into cation exchange membranes that allow only cations to pass through and anion exchange membranes that allow only anions to pass through. This example demonstrates how changing the type of ion exchange membrane can adapt to different types of drug solutions. For instance, the semi-permeable membrane 26 uses nanoscale membrane materials with pore sizes less than 0.4 nm, exhibiting high selective filtration capabilities and preventing water leakage. When selecting the liner 25, different materials can be chosen based on the characteristics of different drug delivery sites. For example, skin requires breathability and fit, so a liner 25 made of materials such as polyethylene or polyurethane can be selected. Similarly, mucous membranes may require biocompatibility and adhesion, so a liner 25 made of materials such as chitosan or hydroxypropyl cellulose can be selected.

[0040] In this embodiment, the electrode storage compartment 22 inside the main housing 20 is located near the top wall of the main housing 20. The top wall of the main housing 20 also has a first power line interface 210 communicating with the electrode storage compartment 22. The main electrode plate 23 is placed inside the electrode storage compartment 22 of the main housing 20, and the main electrode plate 23 is connected to an external power line 4 via the first power line interface 210 and connected to one of the current output interfaces 12 on the controller. The sub-housing 31 forms a storage space to accommodate the sub-electrode plate 32. The sub-housing 31 includes opposing top and bottom walls. The bottom wall of the sub-housing 31 has a second power line interface 34. The sub-electrode plate 32 is placed inside the sub-housing 31, and the sub-electrode plate 32 is connected to an external power line 4 via the second power line interface 34 and connected to another current output interface 12 on the controller. The top wall of the sub-housing 31 has a sub-electrode replacement port for replacing the sub-electrode plate 32. A soft cloth 33 is provided at the sub-electrode replacement port to better fit the skin surface. In addition, the main housing 20 and the secondary housing 31 are made of waterproof and insulating materials.

[0041] In this embodiment, one end of each of the two straps 5 is fixed to both sides of the main housing 20, and the other end of each strap 5 is provided with Velcro 51 and is bound to the secondary housing 31, so that the main electrode component 2, the secondary electrode component 3, and the two straps 5 together form a wearing space. The two straps 5 are made of elastic material, and the size of the wearing space can be changed by adjusting the length of the two straps 5 to adapt to different drug delivery sites on the human body.

[0042] In this embodiment, the main electrode component 2 and the auxiliary electrode component 3 can be selected with shapes suitable for different drug delivery sites. The shapes of the main electrode component 2 and the auxiliary electrode component 3 are preferably square or circular. For example, when the drug delivery site is the human face, the main electrode component 2 and the auxiliary electrode component 3 are circular. Or, for example, when the drug delivery site is the human leg, the main electrode component 2 and the auxiliary electrode component 3 are square with a curved shape to facilitate better adhesion to the skin.

[0043] The directional liquid drug delivery device proposed in this invention can be applied to fields such as tumor treatment, cancer chemotherapy, pain management, and local treatment. For better understanding, a detailed explanation will now be given using a local treatment of a patient's leg as an example. In this example, the directional liquid drug delivery device is a dedicated instrument for the directional delivery of liquid drugs used in local treatment. Before treatment, the drug delivery component is worn on the designated drug delivery site on the patient's thigh, ensuring that the padding 25 in the main electrode component 2 and the fleece 33 in the auxiliary electrode component 3 are in contact with the skin; the drug is injected into the drug storage chamber 21 in the main electrode component 2 through the drug port 28; the main electrode plate 23 in the main electrode component 2 and the auxiliary electrode plate 32 in the auxiliary electrode component 3 are connected to the two current output interfaces 12 on the controller via two power lines 4. During treatment, press the power switch button 16 on the controller to turn on the power. The current displayed on the screen 17 can also be adjusted to a comfortable value for the patient using the current intensity adjustment button 15. During treatment, a DC electric field is generated between the main electrode plate 23 and the secondary electrode plate 32, ionizing the molecules in the medication solution into ions. These ions then move directionally under the influence of the electric field (i.e., from the side closer to the main electrode plate 23 towards the side closer to the secondary electrode plate 32). Consequently, the medication ions in the medication storage chamber 21 flow sequentially through the medication permeation hole 24, the semi-permeable membrane 26, and the pad 25 to the skin, entering the body through the skin to achieve the therapeutic effect. After treatment, turn off the power and remove the medication delivery component.

[0044] The directional liquid drug delivery device proposed in this invention allows for the direct use of liquid medications and enables the automatic replacement of other medication solutions, offering greater flexibility. The main housing 20 of the main electrode component 2 includes a medication storage chamber 21 and an electrode storage chamber 22, increasing the distance between the main electrode plate 23 and the skin. This effectively prevents skin burns caused by the generation of acid and alkali byproducts at the electrode plate due to electrolysis, making it safer. Therefore, the device offers flexibility, repeatability, and safety in its use.

[0045] Example 2

[0046] like Figure 5 As shown, the difference between this embodiment and Embodiment 1 is that the controller further includes two current direction switching buttons, namely, the main electrode positive power button 13 and the main electrode negative power button 14. The main electrode positive power button 13 and the main electrode negative power button 14 are electrically connected to the main control circuit board and are exposed at the front of the housing 11. The main electrode positive power button 13 is used to control the main electrode plate 23 to be positively charged, and the main electrode negative power button 14 is used to control the main electrode plate 23 to be negatively charged. It can be understood that the main electrode plate 23 and the auxiliary electrode plate 32 are in the same closed circuit. Controlling the main electrode plate 23 to be positively charged via the main electrode positive power button 13 also controls the auxiliary electrode plate 32 to be negatively charged; similarly, controlling the main electrode plate 23 to be negatively charged via the main electrode negative power button 14 also controls the auxiliary electrode plate 32 to be positively charged.

[0047] The advantage of setting two current direction switching buttons in this embodiment is that it takes into account that the polarity of the drug solution ions directly affects their migration behavior in the electric field. It can switch the positive / negative charge of the main electrode plate 23 as needed to adapt to drug solutions of different polarities. Compared with changing the connection method of the power cord 4, it is more flexible, convenient and saves time and effort.

[0048] To better understand, two application examples will now be provided. For instance, the medication injected into the drug storage chamber 21 of the main electrode component 2 is potassium chloride (potassium ions are cations), which can increase neuromuscular excitability and is used to treat peripheral neuritis and nerve paralysis. In this application example, the main electrode plate 23 can be positively charged and the auxiliary electrode plate 32 negatively charged via the main electrode positive charge button 13. As another example, the medication injected into the drug storage chamber 21 of the main electrode component 2 is edible vinegar (the main component of edible vinegar is acetic acid, which contains anions), which can treat bone hyperplasia. In this application example, the main electrode plate 23 can be negatively charged and the auxiliary electrode plate 32 positively charged via the main electrode negative charge button 14. Therefore, by switching the positive / negative charge of the main electrode plate 23 as needed, both anion- and cation-containing medications are introduced into the body from the main electrode component 2 side. This eliminates the need for a medication storage space in the auxiliary electrode component 3, reducing the size of the device and making it easier to carry.

[0049] Example 3

[0050] like Figure 6 , Figure 7 As shown, the difference between this embodiment and Embodiment 2 is that the main housing 20 of the main electrode component 2 also has a main electrode replacement port 29 communicating with the electrode storage compartment 22. Preferably, the top wall of the main housing 20 has a main electrode replacement port 29 and a right-hand flap for covering the main electrode replacement port 29, and the main electrode replacement port 29 and the liquid outlet 28 are located at opposite ends of the top wall of the main housing 20, making the structure of the device more compact. Of course, the main electrode replacement port 29 can also be located at other positions on the main housing 20, as long as it is convenient to replace the main electrode plate 23.

[0051] In this embodiment, the main housing 20 is provided with a main electrode replacement port 29, which allows for the replacement of the type of main electrode plate 23 (polar / non-polar electrode plate) to suit different types of drug solutions, in order to prevent electrolysis products from destroying the activity of the drug solution.

[0052] Understandably, the main electrode plate 23 can be categorized into non-polar and polar electrode plates. Non-polar electrode plates are primarily made of inert materials such as gold, platinum, and copper. During electrochemical processes, no electrochemical reaction occurs on the electrode surface, making them suitable for solutions that are easily destroyed by electrolysis products, such as antibiotics like penicillin and tetracycline, to prevent pH changes from causing drug inactivation. Polar electrodes, on the other hand, may be made of precious metals such as gold and platinum, or inexpensive materials such as iron and chromium, depending on the requirements. During electrochemical processes, an electrochemical reaction occurs on the electrode surface, making them suitable for solutions that are not easily destroyed by electrolysis products, such as streptomycin and chloramphenicol.

[0053] Example 4

[0054] The difference between this embodiment and Embodiment 1 is that the main housing 20 in the main electrode component 2 divides its internal space into a drug storage chamber 21 and an electrode storage chamber 22 by a flexible partition plate. The main electrode plate 23 placed in the electrode storage chamber 22 is a flexible electrode plate. The main electrode plate 23 is in contact with the flexible partition plate. In addition, an extrusion member is provided in the electrode storage chamber 22. The fixed end of the extrusion member is connected to the top wall of the main housing 20, and the telescopic end of the extrusion member abuts against the main electrode plate 23.

[0055] In this embodiment, the main electrode plate 23 is deformed by the extrusion component, thereby making the volume of the drug storage chamber 21 variable. This achieves the purpose of reducing the volume of the drug storage chamber 21 as the amount of drug decreases during treatment, so as to prevent the main electrode plate 23 and the auxiliary electrode plate 32 from failing to form a DC electric field due to excessive air in the drug storage chamber 21, and further improve the treatment effect.

[0056] Understandably, the squeezing element could be a spring, etc. Before treatment, medication is injected into the medication storage chamber 21 through the medication port 28. When the medication reaches a certain amount, the squeezing element will contract as the medication increases until it reaches its limit. During treatment, as medication ions flow out of the medication storage chamber 21 and enter the body through the skin, the squeezing element begins to extend and pushes the main electrode plate 23 and the flexible partition plate to deform, reducing the volume of the medication storage chamber 21. This ensures that the remaining medication still fills the medication storage chamber 21, improving the treatment effect. This design also reduces the requirements for how the medication delivery components are worn. For example, the main electrode component 2 and the auxiliary electrode component 3 can be attached to the front and back sides or the upper and lower sides of the patient's thighs, which can make the volume of the medication storage chamber 21 match the amount of medication and reduce the amount of air in the medication storage chamber 21.

[0057] In this embodiment, a liquid level detection sensor and / or an air detection sensor may also be provided in the liquid storage chamber 21 to detect whether the liquid storage chamber 21 is full of liquid or whether a set dose of liquid has been added.

[0058] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A directional liquid drug delivery device, comprising a controller and a drug delivery assembly, wherein the controller includes a housing, a main control circuit board disposed inside the housing, and two current output interfaces electrically connected to the main control circuit board and exposed outside the housing; characterized in that, The drug delivery assembly includes a main electrode component and a secondary electrode component. The main electrode component includes a main housing with a drug storage chamber and an electrode storage chamber, a main electrode plate placed in the electrode storage chamber, a semi-permeable membrane, and a liner. The main housing has a drug permeation hole communicating with the drug storage chamber and a drug port for injecting or extracting drug. The liner is disposed on the side of the main housing with the drug permeation hole. The semi-permeable membrane is located between the main housing and the liner. The secondary electrode component includes a secondary housing and a secondary electrode plate disposed in the secondary housing. The main housing and the secondary housing are connected by straps and form a wearable space. The main electrode plate and the secondary electrode plate are connected to the two current output ports via power lines.

2. The directional liquid drug delivery device as described in claim 1, characterized in that, The controller also includes two current direction switching buttons and one current intensity adjustment button that are electrically connected to the main control circuit board and exposed outside the housing. The two current direction switching buttons include a main electrode positive button for controlling the main electrode plate to be positively charged and a main electrode negative button for controlling the main electrode plate to be negatively charged.

3. The directional liquid drug delivery device as described in claim 1, characterized in that, The main housing is also provided with a main electrode replacement port that communicates with the electrode storage compartment. The main electrode replacement port is used to replace different types of main electrode plates, including polar electrode plates or non-polar electrode plates.

4. The directional liquid drug delivery device as described in claim 1, characterized in that, Two snap fasteners are provided at intervals on the main housing, and the padding is connected to the main housing by the two snap fasteners so that the padding can be replaced.

5. The directional liquid drug delivery device as described in claim 1, characterized in that, The main casing shares the same liquid inlet and outlet.

6. The directional liquid drug delivery device as described in claim 1, characterized in that, The sub-shell has a sub-electrode replacement port for replacing the sub-electrode plate. The sub-electrode replacement port is provided with a velvet cloth. The end of the strap near the sub-shell is provided with Velcro for adjusting the length and securing the sub-shell.

7. The directional liquid drug delivery device as described in claim 1, characterized in that, The main housing and the secondary housing are made of waterproof and insulating materials.

8. The directional liquid drug delivery device as described in claim 1, characterized in that, The directional liquid drug delivery device is a specialized instrument for the directional delivery of liquid drugs used in local treatment.

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