Liquid driving structure of microfluidic chip

Abstract

The utility model relates to a kind of driving structure, belong to microfluidic chip technical field, specifically a kind of liquid driving structure of microfluidic chip;In the utility model, when elastic film is used for a long time, limit frame is removed, so that limit frame and fixed frame separate, then elastic film is removed, new elastic film is sleeved on limit column, then limit frame is covered, and elastic film is fixed, so that elastic film is replaced easily, cooperation is carried out by motor, carousel, threaded rod, threaded block, connecting column, sliding frame and extruding roller, the speed of reciprocating movement of extruding roller is adjusted by the rotation of motor, so as to adjust the flow rate of liquid, when the flow of liquid needs to be adjusted, threaded rod is rotated, since threaded block is screw thread connected on threaded rod, so threaded rod moves along with the rotation of threaded block, drives connecting column to move, so that the range of sliding frame movement reduces, the extrusion degree of extruding roller to elastic film is reduced, so as to control the flow of liquid, improve the practicability of the device.

Description

Technical Field

[0001] This utility model relates to the field of microfluidic chip technology, specifically a liquid-driven structure for a microfluidic chip. Background Technology

[0002] Microfluidic chips are commonly used to precisely control the flow of tiny volumes of liquid, with applications in biomedical detection, chemical analysis, and other fields. The liquid-driven structure is a key component, as it determines the flow pattern, speed, and precision of the liquid.

[0003] Chinese patent CN213913852U discloses a microfluidic chip liquid driving device. It creates a liquid flow channel on the chip by leaving a variable cavity in the middle layer inside the shell, which is connected to an inlet channel and an outlet channel. One-way valves are installed in the inlet and outlet channels to control the unidirectional flow of liquid within the channels. When the driving device is working, external force repeatedly squeezes the variable cavity to cause deformation, allowing liquid to enter from the inlet channel and flow out from the outlet channel. This utilizes the change in air pressure within the variable cavity as the driving force, thus achieving unidirectional liquid flow within the microfluidic chip channels, preventing backflow and ensuring the normal reaction of liquid reagents or samples.

[0004] In the above technical solution, the elastic membrane is squeezed by external force to compress the variable cavity, allowing liquid to enter from the inlet channel. However, the elasticity of the elastic membrane will weaken after long-term use, thus weakening the effect of external force squeezing the elastic membrane and causing changes in the liquid flow rate.

[0005] Based on this, the present invention proposes a liquid-driven structure for a microfluidic chip. Utility Model Content

[0006] To address the aforementioned technical problems, this invention proposes a liquid-driven structure for a microfluidic chip. The structure utilizes a fixed frame and a limiting frame to facilitate the replacement of the elastic membrane, preventing its elasticity from weakening after prolonged use. A motor drives a squeezing roller to compress the elastic membrane. By controlling the motor's rotation, the liquid flow rate can be controlled. Adjusting the lifting height of the squeezing roller via a threaded rod controls the liquid flow rate, thus improving the device's practicality.

[0007] The technical solution to achieve the purpose of this utility model is: a liquid driving structure for a microfluidic chip, including an upper shell and a lower shell, with an intermediate layer between the upper shell and the lower shell, and an inlet channel, a connecting channel and an outlet channel formed in the intermediate layer, wherein the inlet channel and the outlet channel are connected through the connecting channel, and further comprising;

[0008] A cavity is formed in the intermediate layer. A fixed frame is fixedly connected inside the cavity. Multiple limiting posts are fixedly connected to the fixed frame. An elastic membrane is sleeved on the limiting posts. The limiting posts are engaged with the limiting frame. A through hole is formed in the intermediate layer. The cavity is connected to the connecting channel through the through hole.

[0009] Preferably, one check valve one and one check valve two are fixedly connected to both ends of the connection channel, respectively.

[0010] Preferably, a motor is fixedly connected inside the intermediate layer, and a turntable is fixedly connected to the output shaft of the motor.

[0011] Preferably, the turntable is internally threaded with a threaded rod, and a threaded block is threadedly connected to the threaded rod, the threaded block being slidably connected inside the turntable.

[0012] Preferably, a connecting post is rotatably connected to the threaded block, and a sliding frame is slidably connected inside the cavity.

[0013] Preferably, the sliding frame has a groove, the connecting column is disposed in the groove, and an extrusion roller is fixedly connected to the sliding frame.

[0014] Compared with existing technologies, the significant advantages of this invention are:

[0015] Firstly, in this utility model, after the elastic membrane has been used for a long time, the limiting frame is removed to separate the limiting frame from the fixing frame. Then, the elastic membrane is removed, and a new elastic membrane is fitted onto the limiting post. Finally, the limiting frame is covered to fix the elastic membrane, making it easy to replace the elastic membrane.

[0016] Secondly, in this invention, the motor, turntable, threaded rod, threaded block, connecting column, sliding frame, chute, and extrusion roller work together to regulate the reciprocating speed of the extrusion roller by controlling the rotation of the motor, thereby regulating the flow rate of the liquid. When it is necessary to regulate the flow rate of the liquid, the threaded rod is rotated. Since the threaded block is threadedly connected to the threaded rod, the threaded rod moves with the rotation of the threaded block, driving the connecting column to move. This reduces the range of movement of the sliding frame, decreases the degree of extrusion of the extrusion roller on the elastic membrane, thereby controlling the flow rate of the liquid and improving the practicality of the device. Attached Figure Description

[0017] The present invention will be further explained below with reference to the accompanying drawings and embodiments:

[0018] Figure 1 This is a three-dimensional structural schematic diagram of the present invention;

[0019] Figure 2 This is a cross-sectional structural schematic diagram of the present invention;

[0020] Figure 3It is an exploded structural schematic diagram of the fixed frame and the limit frame in the utility model;

[0021] Figure 4 is Figure 1 an enlarged structural view of part A in

[0022] Explanation of reference numerals:

[0023] 1. Upper shell; 2. Lower shell; 3. Intermediate layer; 4. Liquid inlet channel; 5. Connection channel; 6. Liquid outlet channel; 7. Check valve one; 8. Check valve two; 9. Cavity; 10. Through hole; 11. Fixed frame; 12. Limit column; 13. Elastic membrane; 14. Limit frame; 15. Motor; 16. Turntable; 17. Threaded rod; 18. Threaded block; 19. Connection column; 20. Sliding frame; 21. Chute; 22. Extrusion roller. Detailed implementation manners

[0024] The present utility model will be described in detail below. The technical solutions in the embodiments of the present utility model are clearly and completely described. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts belong to the scope of protection of the present utility model.

[0025] The present utility model provides a liquid driving structure of a microfluidic chip through improvement. The technical solution of the present utility model is:

[0026] As Figures 1-4 shown, a liquid driving structure of a microfluidic chip includes an upper shell 1 and a lower shell 2. An intermediate layer 3 is provided between the upper shell 1 and the lower shell 2. A liquid inlet channel 4, a connection channel 5 and a liquid outlet channel 6 are opened in the intermediate layer 3. The liquid inlet channel 4 is connected to the liquid outlet channel 6 through the connection channel 5. The cross-section of the connection channel 5 is in a "U" shape, and further includes;

[0027] A cavity 9 is opened on the intermediate layer 3. A fixed frame 11 is fixedly connected in the cavity 9. The cross-section of the fixed frame 11 is in a "return" shape. A plurality of limit columns 12 are fixedly connected to the fixed frame 11. The limit columns 12 are linearly arrayed on the top of the fixed frame 11. An elastic membrane 13 is sleeved on the limit columns 12. A limit frame 14 is clamped on the limit columns 12. The elastic membrane 13 is fixed by the fixed frame 11 and the limit frame 14, so that the elastic membrane 13 is convenient to disassemble and replace, and to prevent the elasticity of the elastic membrane 13 from weakening after long-term use. A through hole 10 is opened in the intermediate layer 3. The cavity 9 is connected to the connection channel 5 through the through hole 10.

[0028] Furthermore, as Figure 2As shown, one-way valve 1 and one-way valve 2 are fixedly connected to both ends of connecting channel 5 respectively. One-way valve 1 is located at one end of connecting channel 5 close to liquid inlet channel 4, so that liquid can only flow into connecting channel 5 through liquid inlet channel 4 and cannot flow back. One-way valve 2 is located at one end of connecting channel 5 close to liquid outlet channel 6, so that liquid can only flow into liquid outlet channel 6 through connecting channel 5 and cannot flow back.

[0029] Further, as Figures 1-4 shown, an electric motor 15 is fixedly mounted on the intermediate layer 3 by bolts. A turntable 16 is fixedly mounted on the output shaft of the electric motor 15 by bolts. By controlling the rotational speed of the electric motor 15, the reciprocating movement speed of the extrusion roller 22 is controlled, that is, the frequency of the extrusion roller 22 extruding the elastic membrane 13, so as to control the flow rate of the liquid.

[0030] Further, as Figures 1-4 shown, a threaded rod 17 is connected to the turntable 16 by internal threads. A threaded block 18 is connected to the threaded rod 17 by threads. The threaded block 18 is slidably connected to the turntable 16. By adjusting the position of the connecting column 19 through the threaded rod 17, the reciprocating movement range of the sliding frame 20 is controlled, so as to control the extrusion degree of the extrusion roller 22 on the elastic membrane 13, and thus control the flow rate of the liquid.

[0031] Further, as Figures 1-4 shown, a connecting column 19 is rotatably connected to the threaded block 18. A sliding frame 20 is slidably connected to the cavity 9. The cross section of the sliding frame 20 is in the shape of a Chinese character 'hui'.

[0032] Further, as Figure 2 shown, a chute 21 is formed in the sliding frame 20. The connecting column 19 is disposed in the chute 21. An extrusion roller 22 is fixedly connected to the sliding frame 20. By rotating the connecting column 19 around the turntable 16, the extrusion roller 22 is driven to reciprocate, and the elastic membrane 13 is periodically extruded.

[0033] The specific working method is as follows: Start the motor 15, its output shaft drives the turntable 16 to rotate, the threaded block 18 rotates accordingly, and drives the connecting column 19 to rotate. Since the connecting column 19 is located in the slide groove 21, the sliding frame 20 moves with the rotation of the connecting column 19, driving the extrusion roller 22 to move back and forth, extruding the elastic membrane 13, so that the liquid enters the inlet channel 4, enters the connecting channel 5 through the one-way valve 7, and then flows out through the connecting channel 5 and the one-way valve 8 into the outlet channel 6. After the elastic membrane 13 has been used for a long time, remove the limit frame 1. 4. Separate the limiting frame 14 from the fixed frame 11, then remove the elastic membrane 13, and place the new elastic membrane 13 on the limiting post 12. Then cover the limiting frame 14 to fix the elastic membrane 13. When it is necessary to adjust the flow rate of the liquid, rotate the threaded rod 17. Since the threaded block 18 is threadedly connected to the threaded rod 17, the threaded rod 17 moves with the rotation of the threaded block 18, which drives the connecting post 19 to move, thereby reducing the range of movement of the sliding frame 20 and reducing the degree of compression of the elastic membrane 13 by the squeezing roller 22, thereby controlling the flow rate of the liquid.

[0034] The technical means disclosed in this utility model are not limited to those described above, but also include technical solutions composed of equivalent substitutions of the above technical features. Matters not covered in this utility model are common knowledge to those skilled in the art.

Claims

1. A liquid driving structure of a microfluidic chip, comprising an upper shell (1) and a lower shell (2), an intermediate layer (3) being arranged between the upper shell (1) and the lower shell (2), characterized in that: The intermediate layer (3) is provided with an inlet channel (4), a connecting channel (5) and an outlet channel (6), the inlet channel (4) and the outlet channel (6) are connected through the connecting channel (5), and also includes; A cavity (9) is formed on the intermediate layer (3). A fixed frame (11) is fixedly connected inside the cavity (9). Multiple limiting posts (12) are fixedly connected on the fixed frame (11). An elastic membrane (13) is sleeved on the limiting post (12). A limiting frame (14) is snapped onto the limiting post (12). A through hole (10) is formed in the intermediate layer (3). The cavity (9) is connected to the connecting channel (5) through the through hole (10).

2. The liquid driving structure of a microfluidic chip according to claim 1, wherein: One-way valve 1 (7) and one-way valve 2 (8) are fixedly connected to both ends of the connection channel (5).

3. The liquid driving structure of a microfluidic chip according to claim 1, wherein: A motor (15) is fixedly connected inside the intermediate layer (3), and a turntable (16) is fixedly connected to the output shaft of the motor (15).

4. The liquid driving structure of a microfluidic chip according to claim 3, wherein: The turntable (16) is internally threaded with a threaded rod (17), and a threaded block (18) is threadedly connected to the threaded rod (17). The threaded block (18) is slidably connected inside the turntable (16).

5. The liquid driving structure of a microfluidic chip according to claim 4, wherein: A connecting column (19) is rotatably connected to the threaded block (18), and a sliding frame (20) is slidably connected inside the cavity (9).

6. The liquid driving structure of a microfluidic chip according to claim 5, wherein: The sliding frame (20) is provided with a sliding groove (21), the connecting column (19) is provided in the sliding groove (21), and the squeezing roller (22) is fixedly connected to the sliding frame (20).

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