A stirred reactor for glutamate dehydrogenase
By designing coaxial, counter-rotating stirring rods and grinding components, the problem of existing reactors being unable to crush solid materials was solved, improving stirring efficiency and reducing manpower consumption, thus achieving a highly efficient reactor with controlled vessel temperature and cleanliness.
Patent Information
- Application Number
- CN202520921947.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-12
- Publication Date
- 2026-06-26
- Estimated Expiration
- 2035-05-12
AI Technical Summary
Existing stirred reactors for glutamate dehydrogenase cannot effectively pulverize solid substrates during mixing, resulting in time-consuming and labor-intensive processes that affect work efficiency.
A stirred reactor comprising a stirring assembly and a heat preservation assembly was designed. Solid materials are crushed by a coaxially rotating stirring rod and a grinding element. The temperature is regulated by a PLC controller and a cleaning system is used to ensure reaction efficiency and reactor cleanliness.
It achieves effective crushing of solid materials, improves stirring efficiency, saves manpower, and ensures normal reaction and cleanliness of the vessel through temperature control and cleaning systems, thereby reducing costs.
Smart Images
Figure CN224411776U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of reaction vessel technology, specifically to a stirred reaction vessel for glutamate dehydrogenase. Background Technology
[0002] A reaction vessel is a closed container used for chemical reactions and is widely used in many fields such as chemical industry, pharmaceutical industry, food industry, and materials industry. A stirred reaction vessel for glutamate dehydrogenase is a device specifically designed for glutamate dehydrogenase-related reaction processes.
[0003] Working principle:
[0004] Material mixing: The coaxial and counter-rotating stirring rod driven by the motor is used to fully stir the mixture, so that the glutamate dehydrogenase, substrate and other reaction media in the reactor form a flowing liquid flow to ensure full reaction. The substrate is fully ground by the grinding device to increase the reaction surface area and accelerate the reaction rate.
[0005] Temperature control: The heating or cooling device of the reactor is used to control the reaction temperature. It adopts a jacketed method. When heating is required, the heat transfer oil is heated by electric heating tubes, and the heat is transferred to the material inside the reactor through the wall of the reactor body or coil. When cooling is required, the electric heating tubes are de-energized, and the water pump is driven to use the low temperature cooling water or chilled brine in the cooling chamber to remove the heat from the heat transfer oil.
[0006] High-efficiency cleaning: The stirring rod has a wall-scraping brush to prevent clumping. An external device is provided to lift the complex stirring device, allowing manual cleaning of hard-to-reach areas. At the same time, a three-dimensional high-pressure cleaning nozzle is used to clean the cylinder wall with water from the cooling chamber.
[0007] Existing stirred reactors for glutamate dehydrogenase have the following drawbacks: During the glutamate dehydrogenase reaction, the glutamate dehydrogenase needs to fully dissociate with the reaction substrate. Common glutamate dehydrogenase reactors cannot effectively pulverize solid substrates, resulting in time-consuming and labor-intensive processes that affect work efficiency. Utility Model Content
[0008] The purpose of this invention is to provide a stirred reaction vessel for glutamate dehydrogenase, in order to solve the problem in the above-mentioned background technology that the reaction vessel cannot crush the added solid material during stirring and mixing, resulting in wasted manpower and reduced production efficiency.
[0009] To achieve the above objectives, the present invention provides the following technical solution: a stirred reaction vessel for glutamate dehydrogenase, comprising a support, a vessel body and a vessel lid, wherein the vessel body is located below the support, the vessel lid is located between the support and the vessel body, and a movable component is provided between the vessel lid and the support;
[0010] The lid is equipped with a stirring component for stirring the vessel body;
[0011] The support frame is equipped with insulation components to keep the vessel body warm;
[0012] The stirring assembly includes a first motor detachably mounted on the vessel lid. A rotating rod is detachably mounted on the end of the first motor. A first gear is fixedly mounted on the rotating rod. A fifth gear is meshed with the side of the first gear. A second gear is meshed with the side of the first gear. A third gear is meshed with the side of the second gear. The ends of the second and third gears are rotatably connected to the vessel lid. A fourth gear is meshed with the side of the third gear and is rotatably connected to the rotating rod. The fourth gear is located directly below the first gear. A stirring element is located below the fourth gear. A sixth gear is meshed with the side of the fourth gear. The sixth gear is located directly below the first gear. A grinding element is located between the sixth gear and the fifth gear.
[0013] Preferably, the insulation component includes an insulation sleeve fitted onto the vessel body, an electric heating element detachably installed inside the insulation sleeve, heat-conducting oil filling the insulation sleeve, a thermal resistance temperature sensor detachably installed inside the insulation sleeve, a cooling chamber formed on the support, a first pipe detachably connected between the bottom of the cooling chamber and the bottom side of the insulation sleeve, a first water pump detachably installed on the first pipe, a third pipe detachably connected to the side of the cooling chamber, a first solenoid valve detachably installed on the third pipe, a second pipe detachably connected between the bottom of the cooling chamber and the top side of the insulation sleeve, a cooling pipe detachably installed between the second pipe and the first pipe, a water storage chamber formed on the support and located at the top of the cooling chamber, a through hole formed between the water storage chamber and the cooling chamber, a second water pump detachably installed at the bottom of the water storage chamber, a fifth pipe detachably installed at the end of the second water pump, a cleaning component connected to the end of the fifth pipe, a fourth pipe detachably installed on the side of the water storage chamber, and a second solenoid valve detachably installed on the fourth pipe.
[0014] Preferably, the movable component includes a slide groove formed on the bracket, a second motor detachably mounted on one end of the slide groove, a lead screw detachably mounted on the end of the second motor, the end of the lead screw rotatably connected to the other end of the slide groove, a limiting block adapted to the slide groove detachably mounted inside the slide groove, a first slider adapted to the slide groove threadedly connected to the lead screw, and the first slider being located to the side of the limiting block, a first hydraulic cylinder detachably mounted on the bottom of the first slider, and the end of the first hydraulic cylinder detachably mounted on the vessel lid, a second slider adapted to the slide groove threadedly connected to the lead screw, and the first slider being located between the second slider and the limiting block.
[0015] Preferably, the stirring component includes a sliding sleeve detachably mounted on the fourth gear, a stirring frame fixedly mounted on the sliding sleeve, a fixing block detachably mounted on the bottom of the stirring frame, a brush detachably mounted on the stirring frame, a first stirring rod detachably mounted inside the stirring frame, several sets of the first stirring rods being arranged linearly and symmetrically, a rotating rod end inserted into the fixing block, and a second stirring rod detachably mounted on the rotating rod, several sets of the second stirring rods being arranged linearly and symmetrically.
[0016] Preferably, the transmission component includes a second gear rotatably connected to the lid of the vessel, with the inner side of the first gear meshing with the outer side of the second gear, a third gear meshing with the side of the second gear, and the end of the third gear rotatably connected to the lid of the vessel. The outer side of the third gear meshes with the inner side of the fourth gear, and the sixth gear rotatably connected to the lid of the vessel.
[0017] Preferably, the cleaning component includes a second hydraulic cylinder detachably mounted on the bottom of the second slider, a three-dimensional high-pressure cleaning nozzle detachably mounted on the end of the second hydraulic cylinder, and a fifth pipe detachably mounted on the end of the three-dimensional high-pressure cleaning nozzle. The three-dimensional high-pressure cleaning nozzle includes a third motor detachably mounted on the second hydraulic cylinder, a first rotating seat detachably mounted on the end of the third motor, a fourth motor detachably mounted on the first rotating seat, a second rotating seat detachably mounted on the end of the fourth motor, and two nozzles symmetrically arranged on the second rotating seat.
[0018] Preferably, a first feed pipe is detachably installed on the lid, a second feed pipe is detachably installed on the lid, and the second feed pipe is located to the side of the first feed pipe. A solid feeding port is opened on the lid, located to the side of the second feed pipe and the first feed pipe, and the solid feeding port is located above the grinding tank. A fixing groove adapted to the fixing block is opened at the bottom of the lid, and a discharge pipe is detachably installed at the bottom of the fixing groove. A third solenoid valve is detachably installed on the discharge pipe.
[0019] Preferably, a PLC controller is detachably mounted on the bracket. The PLC controller is used to control the third solenoid valve, the first motor, the heating element, the thermal resistance temperature sensor, the first water pump, the second water pump, the first solenoid valve, the second solenoid valve, the third motor, the fourth motor, the second motor, the first hydraulic cylinder, and the second hydraulic cylinder. The third solenoid valve, the first motor, the heating element, the thermal resistance temperature sensor, the first water pump, the second water pump, the first solenoid valve, the second solenoid valve, the third motor, the fourth motor, the second motor, the first hydraulic cylinder, the second hydraulic cylinder, the PLC controller, and the external power supply are linearly connected.
[0020] Compared with the prior art, the beneficial effects of this utility model are:
[0021] 1. In this utility model, a first motor drives a rotating rod to rotate, which in turn drives a first gear to rotate. The first gear drives a second gear to rotate, which in turn drives a third gear to rotate. The third gear drives a fourth gear to rotate in the opposite direction to the first gear, causing the sliding sleeve to rotate in the opposite direction to the rotating rod. The stirring frame detachably mounted on the sliding sleeve and the first stirring rod rotate in the opposite direction to the second stirring rod detachably mounted on the rotating rod, achieving coaxial but opposite-direction rotation for more thorough mixing. At the same time, the brush mounted on the stirring frame can clean the cylinder wall to prevent clumping. The first and fourth gears rotate in opposite directions, causing the fifth and sixth gears to rotate in opposite directions, driving the upper and lower grinding blocks to rotate in opposite directions. This causes the grinding groove in the upper grinding block and the grinding head detachably mounted in the lower grinding block to rotate in opposite directions, thus achieving pre-grinding of solid materials. Through the stirring assembly, the problem of the reactor being unable to crush the added solid materials during mixing, resulting in wasted manpower and reduced production efficiency, is solved.
[0022] 2. In this invention, during stirring, a thermal resistance temperature sensor controls the temperature of the vessel body via a PLC controller. When the temperature is too low, power is supplied to the heating element, which heats the heat-conducting oil inside the insulation jacket to raise the temperature of the vessel body. When the temperature is too high, the first water pump is driven, and the heat-conducting oil begins to flow, passing through the cooling chamber to exchange heat with the cold water inside, and then returning to the insulation jacket to cool the vessel body, thereby controlling the temperature of the vessel body. Cold water enters the cooling chamber through the third pipe, enters the water storage chamber through the through hole, and then flows out through the fourth pipe. When cleaning is required, the first pipe is closed. Two solenoid valves open the second water pump, transporting water from the storage chamber to the three-dimensional high-pressure cleaning nozzle. This drives the first hydraulic cylinder, raising the vessel lid. The PLC controller then drives the second motor, stopping the first slider when it reaches the limit block. At this point, the three-dimensional high-pressure cleaning nozzle is positioned directly above the vessel. The second hydraulic cylinder is then activated, allowing the nozzle to extend into the vessel for cleaning. Simultaneously, the vessel lid is manually rinsed to clean hard-to-reach areas. The insulation components maintain the vessel temperature, ensuring the reaction proceeds normally. Cooling water is also recycled for cleaning, saving costs. Attached Figure Description
[0023] Figure 1 This is a schematic diagram of the overall structure of a stirred reaction vessel for glutamate dehydrogenase proposed in this utility model;
[0024] Figure 2 This is a schematic diagram of the overall structure of a stirred reaction vessel for glutamate dehydrogenase proposed in this utility model;
[0025] Figure 3 This is a schematic diagram of the cleaning process of a stirred reaction vessel for glutamate dehydrogenase proposed in this utility model;
[0026] Figure 4This is a front view of the stirred reaction vessel for glutamate dehydrogenase proposed in this utility model during cleaning.
[0027] Figure 5 This is a schematic diagram of the extended structure at point A of a stirred reaction vessel for glutamate dehydrogenase proposed in this utility model;
[0028] Figure 6 This is a schematic diagram of the grinding component structure of a stirred reaction vessel for glutamate dehydrogenase proposed in this utility model;
[0029] Figure 7 This is a schematic diagram of the structure of a stirred reaction vessel for glutamate dehydrogenase proposed in this utility model.
[0030] Figure 8 This is a schematic diagram of the lid structure of a stirred reaction vessel for glutamate dehydrogenase proposed in this utility model.
[0031] In the diagram: 1. Support; 2. Kettle body; 21. Fixing groove; 22. Discharge pipe; 23. Third solenoid valve; 3. Kettle lid; 31. First feed pipe; 32. Second feed pipe; 33. Solid feed port; 4. Stirring assembly; 41. First motor; 42. Rotating rod; 43. First gear; 44. Second gear; 45. Third gear; 46. Fourth gear; 47. Fifth gear; 48. Sixth gear; 49. Sliding sleeve; 410. Stirring frame; 411. Fixing block; 412. Brush; 413. First stirring rod; 414. Second stirring rod; 415. Upper grinding block; 416. Grinding groove; 417. Lower grinding block; 418. Cavity; 419. Grinding head; 420. Filter screen; 5. Insulation assembly; 51. Insulation sleeve; 52. Electric heating element. 53. Thermal resistance temperature sensor; 54. First pipe; 55. Cooling chamber; 56. Water storage chamber; 57. Through hole; 58. Second pipe; 59. Cooling pipe; 510. First water pump; 511. Second water pump; 512. Fifth pipe; 513. Third pipe; 514. First solenoid valve; 515. Fourth pipe; 516. Second solenoid valve; 517. Three-dimensional high-pressure cleaning nozzle; 518. Third motor; 519. First rotating seat; 520. Fourth motor; 521. Second rotating seat; 522. Spray pipe; 6. Moving part; 61. Slide groove; 62. Second motor; 63. Lead screw; 64. Limit block; 65. First slider; 66. Second slider; 67. First hydraulic cylinder; 68. Second hydraulic cylinder; 7. PLC controller. Detailed Implementation
[0032] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0033] Example 1
[0034] Please see Figure 1 - Figure 8 The diagram shows a stirred reactor for glutamate dehydrogenase, comprising a support 1, a reactor body 2, and a reactor lid 3. The reactor body 2 is located below the support 1, and a fixing groove 21 is provided at the bottom of the reactor body 2. A discharge pipe 22 is detachably installed at the bottom of the fixing groove 21, and a third solenoid valve 23 is detachably installed on the discharge pipe 22. The third solenoid valve 23 is used to control the discharge from the reactor body 2. The reactor lid 3 is located between the support 1 and the reactor body 2, and a first feed pipe 31 is detachably installed on the reactor lid 3. Since glutamate dehydrogenase is added to the first feed pipe 31, a second feed pipe 32 is detachably installed on the reactor lid 3. The second feed pipe 32 is used to add coenzyme and is located to the right of the first feed pipe 31. A solid feed port 33 is provided on the reactor lid 3. The solid feed port 33 is used to add solid materials and is located in front of the second feed pipe 32 and the first feed pipe 31. A movable component 6 is provided between the reactor lid 3 and the support 1. The movable component 6 includes components provided on the support 1. The slide 61 has a detachable second motor 62 at its left end and a detachable lead screw 63 at its right end. The right end of the lead screw 63 is rotatably connected to the right end of the slide 61. The second motor 62 drives the lead screw 63 to rotate. A limiting block 64 adapted to the slide 61 is detachably installed inside the slide 61. The limiting block 64 is used for limiting. A first slider 65 adapted to the slide 61 is threadedly connected to the lead screw 63, and the first slider 65 is located to the right of the limiting block 64. The rotation of the lead screw 63 drives the first slider 65 to move. A first hydraulic cylinder 67 is detachably installed at the bottom of the first slider 65, and the bottom of the first hydraulic cylinder 67 is detachably installed on the lid 3. Driving the first hydraulic cylinder 67 can lift or lower the lid 3. A second slider 66 adapted to the slide 61 is threadedly connected to the lead screw 63. The rotation of the lead screw 63 drives the second slider 66 to move, and the first slider 65 is located between the second slider 66 and the limiting block 64.
[0035] A stirring component 4 is provided on the lid 3 for stirring the vessel body 2;
[0036] The stirring assembly 4 includes a first motor 41 detachably mounted on the vessel lid 2. A rotating rod 42 is detachably mounted on the bottom of the first motor 41. A first gear 43 is fixedly mounted on the rotating rod 42. A fifth gear 47 is meshed with the right side of the first gear 43. A fourth gear 46 is rotatably connected to the rotating rod 42. A transmission component is provided between the fourth gear 46 and the first gear 43. The transmission component includes a second gear 44 rotatably connected to the vessel lid 3, with the inner side of the first gear 43 meshing with the outer side of the second gear 44. A third gear 45 is meshed with the side of the second gear 44, and the end of the third gear 45 is rotatably connected to the vessel lid 3. The outer side of the third gear 45 meshes with the inner side of the fourth gear 46. A sixth gear 48 is rotatably connected to the vessel lid 3. The first motor 41 drives the rotating rod 42 to rotate, which in turn drives the first gear 43 to rotate. The first gear 43 drives the second gear 44 to rotate, which in turn drives the third gear 45 to rotate. The third gear 45 drives the fourth gear 46 to rotate in the opposite direction to the rotation of the first gear 43. A stirring component is provided below the fourth gear 46. The stirring component includes a sliding sleeve 49 detachably mounted on the fourth gear 46. A stirring frame 410 is fixedly mounted on the sliding sleeve 49. A fixing block 411 adapted to the fixing groove 21 is detachably mounted at the bottom of the stirring frame 410. The fixing groove 21 and the fixing block 411 are slidably connected to block the fixing groove 21 to prevent excessive liquid from accumulating in the discharge pipe 22, which would lead to insufficient stirring. At the same time, it also helps to stir the material. The frame 410 serves a fixing function, and a brush 412 is detachably installed on the stirring frame 410 for cleaning the cylinder wall and preventing clumping. A first stirring rod 413 is detachably installed inside the stirring frame 410; several sets of the first stirring rod 413 are arranged linearly and symmetrically. The bottom of the rotating rod 42 is inserted into the fixing block 411, and a second stirring rod 414 is detachably installed on the rotating rod 42; several sets of the second stirring rod 414 are arranged linearly and symmetrically. A first motor 41 drives the first stirring rod 413 and the second stirring rod 414 to rotate in opposite directions, making the mixing more thorough. A sixth gear 48 is meshed with the right side of the fourth gear 46, and the sixth gear 48 is connected to the fifth gear... A grinding element is provided between gears 47. The grinding element includes an upper grinding block 415 fixedly connected to the bottom of the fifth gear 47. The upper grinding block 415 has a grinding groove 416, which is located below the solid feed port 33. A lower grinding block 417 is detachably installed on the sixth gear 48, and the lower grinding block 417 is rotatably connected to the upper grinding block 415. A cavity 418 is provided inside the lower grinding block 417. A grinding head 419 is detachably installed in the cavity 418 and inserted into the grinding groove 416. Solid material enters the grinding groove 416 from the solid feed port 33, is ground by the grinding head 419, and then enters the cavity 418. A filter screen 420 is detachably installed at the bottom of the cavity 418 for filtering the ground material.
[0037] The support frame 1 is equipped with a heat preservation component 5 for heat preservation of the vessel body 2;
[0038] The insulation component 5 includes an insulation sleeve 51 fitted onto the vessel body 2. An electric heating element 52 is detachably installed inside the insulation sleeve 51, which is filled with heat-conducting oil. The electric heating element 52 heats the heat-conducting oil to raise the temperature of the vessel body 2. A thermal resistance temperature sensor 53 is detachably installed inside the insulation sleeve 51 to detect the temperature of the vessel body 3. A cooling chamber 55 is provided on the support 1. A first pipe 54 is detachably connected between the bottom of the cooling chamber 55 and the bottom of the rear side of the insulation sleeve 51. A first water pump 510 is detachably installed on the first pipe 54. A third pipe 513 is detachably connected to the left side of the cooling chamber 55. A first solenoid valve 514 is detachably installed; a third pipe 513 is connected to a water source, opening the first solenoid valve 514 to inject water into the cooling chamber 55. A second pipe 58 is detachably connected between the top of the cooling chamber 55 and the top of the front side of the insulation sleeve 51. A cooling pipe 59 is detachably installed between the second pipe 58 and the first pipe 54 for heat exchange of the heat transfer oil, driving the first water pump 510, and the heat transfer oil begins to flow to cool the vessel body 2. A water storage chamber 56 is provided on the support 1, and the water storage chamber 56 is located at the top of the cooling chamber 55. A through hole 57 is provided between the water storage chamber 56 and the cooling chamber 55; cold water flows from the cooling chamber 55. Water enters the water storage chamber 56 through the through-hole 57. A second water pump 511 is detachably installed at the bottom of the water storage chamber 56. A fifth pipe 512 is detachably installed at the top of the second water pump 511. A cleaning component is connected to the end of the fifth pipe 512. The cleaning component includes a second hydraulic cylinder 68 detachably installed at the bottom of the second slider 66. A three-dimensional high-pressure cleaning nozzle 517 is detachably installed at the bottom of the second hydraulic cylinder 68. The second hydraulic cylinder 68 is used to control the raising and lowering of the three-dimensional high-pressure cleaning nozzle 517, and the end of the fifth pipe 512 is detachably installed on the three-dimensional high-pressure cleaning nozzle 517. The second water pump 511 is driven to pump water from the water storage chamber 56. The cleaning process is carried out at a three-dimensional high-pressure cleaning nozzle 517. The three-dimensional high-pressure cleaning nozzle 517 includes a third motor 518 detachably mounted on a second hydraulic cylinder 68. A first rotating seat 519 is detachably mounted on the bottom of the third motor 518. A fourth motor 520 is detachably mounted on the first rotating seat 519. A second rotating seat 521 is detachably mounted on the left end of the fourth motor 520. A nozzle 522 is detachably mounted on the second rotating seat 521. Two nozzles 522 are symmetrically arranged. A fourth pipe 515 is detachably mounted on the left side of the water storage chamber 56. A second solenoid valve 516 is detachably mounted on the fourth pipe 515.Opening the second solenoid valve 516 allows water in the storage chamber to drain from the fourth pipe 515. A PLC controller 7 is detachably mounted on bracket 1. The PLC controller 7 controls the third solenoid valve 23, the first motor 41, the heating element 52, the thermal resistance temperature sensor 53, the first water pump 510, the second water pump 511, the first solenoid valve 514, the second solenoid valve 516, the third motor 518, the fourth motor 520, the second motor 62, the first hydraulic cylinder 67, and the second hydraulic cylinder 68. The PLC controller 7 is linearly connected to an external power supply.
[0039] Working principle:
[0040] In use, the first motor 41 drives the rotating rod 42 to rotate, which in turn drives the first gear 43 to rotate. The first gear 43 drives the second gear 44 to rotate, which in turn drives the third gear 45 to rotate. The third gear 45 then drives the fourth gear 46 to rotate in the opposite direction to the rotation of the first gear 43. This causes the sliding sleeve 49 to rotate in the opposite direction to the rotation of the rotating rod 42. The stirring frame 410, which is detachably mounted on the sliding sleeve 49, and the first stirring rod 413, which is detachably mounted on the rotating rod 42, rotate in the opposite direction to the rotation of the second stirring rod 414. This coaxial, opposite-direction rotation ensures more thorough mixing. Meanwhile, the stirring frame 410 and the first stirring rod 413, which are detachably mounted on the rotating rod 42, rotate in the opposite direction to the rotation of the second stirring rod 414. The brush 412 on the mixing rack 410 can clean the cylinder wall and prevent clumping. The first gear 43 and the fourth gear 46 rotate in opposite directions, causing the fifth gear 47 and the sixth gear 48 to rotate in opposite directions, which drives the upper grinding block 415 and the lower grinding block 417 to rotate in opposite directions. This causes the grinding groove 416 in the upper grinding block 415 and the grinding head 419, which is detachably installed in the lower grinding block 417, to rotate in opposite directions, so as to achieve pre-grinding of solid materials. The stirring assembly 4 solves the problem that the reaction vessel cannot crush the added solid materials during stirring and mixing, which leads to wasted manpower and affects production efficiency.
[0041] During stirring, the thermal resistance temperature sensor 53 controls the temperature of the vessel 2 via the PLC controller 7. When the temperature is too low, DC power is supplied to the heating element 52, which heats the heat transfer oil inside the insulation jacket 51 to raise the temperature of the vessel 2. When the temperature is too high, the first water pump 510 is driven, and the heat transfer oil begins to flow, passing through the cooling chamber 55 to exchange heat with the cold water inside, and then returning to the insulation jacket 51 to cool the vessel 2, thereby controlling the temperature of the vessel 2. Cold water enters the cooling chamber 55 through the third pipe 513, enters the water storage chamber 56 through the through hole 57, and then flows out through the fourth pipe 515. When cleaning is required, the second electromagnetic valve is turned off. Valve 516 opens the second water pump 511, and water in the water storage chamber 56 is transported to the three-dimensional high-pressure cleaning nozzle 517. The first hydraulic cylinder 67 is driven to lift the vessel cover 3. The second motor 62 is driven by the PLC controller to move the first slider 65 to the limit block 64 and stop. At this time, the three-dimensional high-pressure cleaning nozzle 517 is located directly above the vessel body 2. The second hydraulic cylinder 68 is driven to extend the three-dimensional high-pressure cleaning nozzle 517 into the vessel body 2 for cleaning. At the same time, the vessel cover 3 is manually rinsed to facilitate cleaning of dead corners. The temperature of the vessel body 2 is maintained by the heat preservation component 5 to ensure the normal progress of the reaction. At the same time, the cooling water is recovered for cleaning, saving costs.
[0042] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus.
[0043] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A stirred reaction vessel for glutamate dehydrogenase, comprising a support (1), a vessel body (2), and a vessel lid (3), characterized in that: The vessel body (2) is located below the support (1), the vessel lid (3) is located between the support (1) and the vessel body (2), and a movable part (6) is provided between the vessel lid (3) and the support (1). A stirring assembly (4) is provided on the lid (3) for stirring the body (2); The support (1) is equipped with a heat preservation component (5) for heat preservation of the vessel body (2); The stirring assembly (4) includes a first motor (41) detachably mounted on the lid (3), a rotating rod (42) detachably mounted on the end of the first motor (41), a first gear (43) fixedly mounted on the rotating rod (42), a fifth gear (47) meshing with the side of the first gear (43), a fourth gear (46) rotatably connected to the rotating rod (42), a transmission component between the fourth gear (46) and the first gear (43), a stirring component below the fourth gear (46), and a sixth gear (47) meshing with the side of the fourth gear (46). 8) The bottom of the fifth gear (47) is fixedly connected to an upper grinding block (415), and a grinding groove (416) is opened on the upper grinding block (415). The top of the sixth gear (48) is fixedly installed with a lower grinding block (417), and the lower grinding block (417) is rotatably connected to the upper grinding block (415). A cavity (418) is opened in the lower grinding block (417), and a grinding head (419) is detachably installed in the cavity (418). The grinding head (419) is inserted into the grinding groove (416), and a filter screen (420) is detachably installed at the bottom of the cavity (418).
2. The stirred reactor for glutamate dehydrogenase according to claim 1, characterized in that: The insulation component (5) includes an insulation sleeve (51) fitted onto the vessel body (2), a heating element (52) is detachably installed inside the insulation sleeve (51), the insulation sleeve (51) is filled with heat-conducting oil, a thermal resistance temperature sensor (53) is detachably installed inside the insulation sleeve (51), a cooling chamber (55) is provided on the bracket (1), a first pipe (54) is detachably connected between the bottom of the cooling chamber (55) and the bottom of the side of the insulation sleeve (51), a first water pump (510) is detachably installed on the first pipe (54), a third pipe (513) is detachably connected to the side of the cooling chamber (55), a first solenoid valve (514) is detachably installed on the third pipe (513), and the top of the cooling chamber (55) and the insulation sleeve (51) are connected together. 1) A second pipe (58) is detachably connected between the side and the top. A cooling pipe (59) is detachably installed between the second pipe (58) and the first pipe (54). A water storage chamber (56) is provided on the bracket (1), and the water storage chamber (56) is located on the top of the cooling chamber (55). A through hole (57) is provided between the water storage chamber (56) and the cooling chamber (55). A second water pump (511) is detachably installed at the bottom of the water storage chamber (56). A fifth pipe (512) is detachably installed at the end of the second water pump (511). A cleaning component is connected to the end of the fifth pipe (512). A fourth pipe (515) is detachably installed on the side of the water storage chamber (56). A second solenoid valve (516) is detachably installed on the fourth pipe (515).
3. The stirred reactor for glutamate dehydrogenase according to claim 1, characterized in that: The movable component (6) includes a slide groove (61) formed on the bracket (1). A second motor (62) is detachably installed at one end of the slide groove (61). A lead screw (63) is detachably installed at the end of the second motor (62). The end of the lead screw (63) is rotatably connected to the other end of the slide groove (61). A limiting block (64) adapted to the slide groove (61) is detachably installed inside the slide groove (61). A first slider (65) adapted to the slide groove (61) is threadedly connected to the lead screw (63). The first slider (65) is located to the side of the limiting block (64). A first hydraulic cylinder (67) is detachably installed at the bottom of the first slider (65). The end of the first hydraulic cylinder (67) is detachably installed on the lid (3). A second slider (66) adapted to the slide groove (61) is threadedly connected to the lead screw (63). The first slider (65) is located between the second slider (66) and the limiting block (64).
4. The stirred reactor for glutamate dehydrogenase according to claim 1, characterized in that: The stirring component includes a sliding sleeve (49) detachably mounted on a fourth gear (46), a stirring frame (410) fixedly mounted on the sliding sleeve (49), a fixing block (411) detachably mounted on the bottom of the stirring frame (410), a brush (412) detachably mounted on the stirring frame (410), a first stirring rod (413) detachably mounted inside the stirring frame (410), several sets of the first stirring rod (413) are provided, and the first stirring rod (413) is arranged linearly and symmetrically, the end of the rotating rod (42) is inserted into the fixing block (411), a second stirring rod (414) detachably mounted on the rotating rod (42), several sets of the second stirring rod (414) are provided, and the second stirring rod (414) is arranged linearly and symmetrically.
5. The stirred reactor for glutamate dehydrogenase according to claim 1, characterized in that: The transmission component includes a second gear (44) rotatably connected to the lid (3), and the inner side of the first gear (43) meshes with the outer side of the second gear (44). The side of the second gear (44) is meshed with a third gear (45), and the end of the third gear (45) is rotatably connected to the lid (3). The outer side of the third gear (45) meshes with the inner side of the fourth gear (46), and the sixth gear (48) is rotatably connected to the lid (3).
6. The stirred reactor for glutamate dehydrogenase according to claim 2, characterized in that: The cleaning component includes a second hydraulic cylinder (68) detachably mounted on the bottom of the second slider (66). A three-dimensional high-pressure cleaning nozzle (517) is detachably mounted on the end of the second hydraulic cylinder (68), and the end of the fifth pipe (512) is detachably mounted on the three-dimensional high-pressure cleaning nozzle (517). The three-dimensional high-pressure cleaning nozzle (517) includes a third motor (518) detachably mounted on the second hydraulic cylinder (68). A first rotating seat (519) is detachably mounted on the end of the third motor (518). A fourth motor (520) is detachably mounted on the first rotating seat (519). A second rotating seat (521) is detachably mounted on the end of the fourth motor (520). A nozzle (522) is detachably mounted on the second rotating seat (521). Two nozzles (522) are symmetrically arranged.
7. The stirred reactor for glutamate dehydrogenase according to claim 3, characterized in that: The first feed pipe (31) is detachably installed on the lid (3), and the second feed pipe (32) is detachably installed on the lid (3), with the second feed pipe (32) located to the side of the first feed pipe (31). The lid (3) is provided with a solid feeding port (33), which is located to the side of the second feed pipe (32) and the first feed pipe (31), and is located above the grinding tank (416). The bottom of the body (2) is provided with a fixing groove (21) that is compatible with the fixing block (411). The bottom of the fixing groove (21) is provided with a discharge pipe (22), and the discharge pipe (22) is detachably installed with a third solenoid valve (23).
8. The stirred reactor for glutamate dehydrogenase according to claim 2, characterized in that: A PLC controller (7) is detachably mounted on the bracket (1). The PLC controller (7) is used to control the third solenoid valve (23), the first motor (41), the heating element (52), the thermal resistance temperature sensor (53), the first water pump (510), the second water pump (511), the first solenoid valve (514), the second solenoid valve (516), the third motor (518), the fourth motor (520), the second motor (62), the first hydraulic cylinder (67), and the second hydraulic cylinder (68). The third solenoid valve (23), the first motor (41), the heating element (52), the thermal resistance temperature sensor (53), the first water pump (510), the second water pump (511), the first solenoid valve (514), the second solenoid valve (516), the third motor (518), the fourth motor (520), the second motor (62), the first hydraulic cylinder (67), the second hydraulic cylinder (68), and the PLC controller (7) are linearly connected to an external power supply.