A rat smoking device

Abstract

This utility model relates to the field of rat smoking technology and discloses a rat smoking device, including a smoking chamber, a three-way valve, a smoking chamber, and an extraction and delivery component. The three ends of the three-way valve are detachably connected to a first hose, a second hose, and a third hose, respectively. The first hose is detachably connected to the smoking chamber. The smoking chamber is detachably connected to the third hose, and the smoking chamber can be used for burning cigarettes. The extraction and delivery component is detachably connected to the second hose and is used to draw the smoke from the burning cigarette in the smoking chamber through the third hose, the three-way valve, and the second hose. This utility model proposes a rat smoking device that generates smoke through the smoking chamber, which is then delivered to the smoking chamber via hoses and a three-way valve to smoke the rats, simulating the smoking process and avoiding experimental errors. Simultaneously, fresh air is introduced and smoke is expelled, simulating a natural smoking environment, diluting the smoke concentration, ensuring the survival safety of the rats, extending the smoking time, and obtaining more data on the chronic development of COPD.

Description

Technical Field

[0001] This utility model relates to the field of rat fumigation technology, and in particular to a rat fumigation device. Background Technology

[0002] COPD (Chronic Obstructive Pulmonary Disease) is a chronic inflammatory disease of the airways characterized by persistent airflow limitation, progressive destruction of lung parenchyma, and emphysema. Its pathogenesis is complex, involving the interaction of multiple factors such as oxidative stress induced by long-term exposure to harmful particles such as tobacco smoke, airway fibrosis, mucus hypersecretion, alveolar wall destruction, and pulmonary microbiome dysbiosis. Ultimately, it leads to a progressive and irreversible decline in lung function. Clinically, COPD patients not only exhibit persistent symptoms such as dyspnea, cough, and sputum production, but also have repeated hospitalizations due to acute exacerbations. They also have multiple comorbidities such as cardiovascular, metabolic, and skeletal muscle dysfunction, which reduces their quality of life and increases the risk of death.

[0003] To better understand the pathogenesis of COPD, assess disease progression, and develop personalized treatment plans, researchers typically need to obtain a large amount of experimental data based on the specific circumstances of each patient. This data includes, but is not limited to, lung function test results, imaging results, biomarker levels, and changes in the patient's daily activities and symptoms.

[0004] However, under current technological conditions, there is a lack of equipment specifically designed for experimental research on COPD, which greatly limits the development and depth of related research.

[0005] To address the aforementioned problems, this application proposes a rat fumigation device. Utility Model Content

[0006] Based on the technical problems existing in the background art, this utility model proposes a rat fumigation device.

[0007] The present invention provides a rat fumigation device, comprising a fumigation box, a three-way valve, a smoking chamber, and an extraction and conveying component;

[0008] The three-way valve has a first hose, a second hose, and a third hose detachably connected to its three ends, and the first hose is detachably connected to the smoking box.

[0009] The cigarette lighter chamber is detachably connected to the third hose, and the cigarette lighter chamber can be used for burning cigarettes;

[0010] The extraction and conveying component is detachably connected to the second hose, and is used to draw the smoke from the burning cigarette in the lighting chamber into it through the third hose, the three-way valve and the second hose, and then transport it to the smoking chamber through the second hose, the three-way valve and the first hose.

[0011] The back of the fumigation chamber is connected to a fumigation exhaust device for discharging fumes.

[0012] The smoking chamber is connected to a fan on its side that blows air into it.

[0013] Preferably, the cigarette-lighting chamber includes a chamber cylinder, on which a cigarette insert is installed for burning cigarettes, the third flexible hose is connected to the cigarette insert, a dust collection seat is threadedly connected to the bottom of the chamber cylinder, and multiple circumferentially arranged air inlets are provided on the chamber cylinder.

[0014] Preferably, the cigarette insert includes a hollow plug, the top of the chamber has an insertion port, the hollow plug is inserted into the insertion port, the hollow plug has a cavity, the bottom of the hollow plug is connected to a plurality of annular arrays of cigarette mouthpieces located in the chamber, the top of the hollow plug is connected to a second connector, and both ends of the third hose are connected to third plugs, the two third plugs being respectively inserted and engaged with the corresponding ends of the second connector and the three-way valve.

[0015] Preferably, the smoke exhaust component includes a smoke exhaust pipe, the back of the smoking box is connected to the smoke exhaust pipe, and a valve is installed on the smoke exhaust pipe.

[0016] Preferably, the front of the smoking box is connected to a first connector that communicates with its interior, and both ends of the first hose are connected to a first plug, which is respectively inserted into the first connector and the corresponding end of the three-way valve.

[0017] Preferably, the top of the smoking box has an opening, and a sealing plug is inserted into the opening.

[0018] Preferably, the extraction and delivery component is a suction pump, and both ends of the second hose are connected to second plugs. The two second plugs are respectively inserted and engaged with the air inlet of the suction pump and the corresponding end of the three-way valve. The air outlet of the suction pump is connected to a connecting pipe, and a balloon is connected to the connecting pipe.

[0019] Preferably, the extraction and delivery component is a syringe, and the injection head on the syringe is inserted into the second plug at the end of the second tubing away from the three-way valve.

[0020] The above-mentioned technical solution of this utility model has the following beneficial technical effects:

[0021] 1. In use, first remove the cigarette holder from the chamber, insert a lit cigarette into the mouthpiece of the cigarette holder, and then put the cigarette holder back into the chamber. The cigarette burns in the chamber to produce smoke. Place the rat into the fumigation chamber, and the extraction conveyor generates suction, causing the smoke in the chamber to be sucked in sequentially through the third hose, the three-way valve, and the second hose. Then close the passage between the three-way valve and the third hose, and the extraction conveyor works in reverse, delivering the smoke sequentially through the second hose, the three-way valve, and the first hose to the fumigation chamber for fumigation. The fumigated rat can then be sent for testing. This design allows the smoke to enter the fumigation chamber along a predetermined path and flow rate, simulating the process of inhaling smoking smoke, avoiding experimental errors caused by uneven smoke delivery or unstable flow rate, and providing reliable and repeatable experimental data for studying the pathogenesis of COPD.

[0022] 2. To simulate a natural smoking environment, when smoke is introduced into the fumigation chamber to fumigate rats, fresh air from outside can be blown into the chamber by a fan. The smoke inside the chamber can then be exhausted through an exhaust system. By introducing smoke into the chamber, the smoking conditions in a natural environment can be simulated. This design not only makes the environment of the experimental animals closer to that of real smokers, but the introduced fresh air can also dilute the smoke concentration to a certain extent, preventing the rats from dying from excessive smoke concentration in a short period. This not only ensures the survival safety of the experimental animals and avoids experimental interruptions and resource waste due to animal deaths, but also allows the experimental animals to undergo longer fumigation treatment under relatively safe conditions, thereby obtaining more experimental data on the chronic development process of COPD. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the overall structure of a rat fumigation device proposed in this utility model;

[0024] Figure 2 This is a schematic diagram of the back structure of a rat fumigation device proposed in this utility model;

[0025] Figure 3 This is a schematic diagram of the cooperative structure of the three-way valve, the cigarette lighter chamber, and the extraction and conveying component of this utility model;

[0026] Figure 4 This is a schematic diagram of the structure of the cigarette lighter compartment in this practical application;

[0027] Figure 5 This is an internal sectional view of the compartment of this utility model;

[0028] Figure 6 This is a schematic diagram of the structure of the suction pump of this utility model;

[0029] Figure 7 This is a schematic diagram of the syringe of this utility model.

[0030] Reference numerals: 1. Smoking chamber; 101. First connector; 102. Fan; 103. Sealing plug; 2. Three-way valve; 21. First hose; 211. First plug; 22. Second hose; 221. Second plug; 23. Third hose; 231. Third plug; 3. Smoking chamber; 31. Chamber cylinder; 32. Smoking insert; 321. Hollow plug; 322. Second connector; 323. Mouthpiece; 33. Ash collection round seat; 34. Air inlet; 4. Extraction and conveying component; 41. Suction pump; 411. Connecting pipe; 412. Balloon; 42. Syringe; 421. Injection head; 5. Smoke exhaust component; 51. Smoke exhaust pipe; 52. Valve. Detailed Implementation

[0031] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments and accompanying drawings. It should be understood that these descriptions are merely exemplary and not intended to limit the scope of this utility model. Furthermore, descriptions of well-known structures and technologies are omitted in the following description to avoid unnecessarily obscuring the concept of this utility model.

[0032] Example 1

[0033] like Figure 1-7 As shown, the present invention proposes a rat fumigation device, which includes a fumigation box 1, a three-way valve 2, a smoking chamber 3, and an extraction and conveying component 4.

[0034] The three ends of the three-way valve 2 are respectively detachably connected to the first hose 21, the second hose 22 and the third hose 23, and the first hose 21 is detachably connected to the smoking box 1.

[0035] The cigarette lighter compartment 3 is detachably connected to the third flexible hose 23, and the cigarette lighter compartment 3 can be used for burning cigarettes;

[0036] The extraction and conveying component 4 is detachably connected to the second hose 22, and is used to draw the smoke from the burning cigarette in the lighting chamber 3 into it through the third hose 23, the three-way valve 2 and the second hose 22, and then transport it to the smoking chamber 1 through the second hose 22, the three-way valve 2 and the first hose 21.

[0037] The back of the fumigation chamber 1 is connected to a fumigation exhaust component 5 for discharging smoke;

[0038] A fan 102 is connected to the side of the smoking chamber 1 to blow air into it.

[0039] First, place the rat into the smoking chamber 1. Then, light a cigarette in the lighting chamber 3 and activate the extraction conveyor 4. The extraction conveyor 4 generates suction, causing the smoke from the burning cigarette in the lighting chamber 3 to be drawn into the extraction conveyor 4 sequentially through the third hose 23, the three-way valve 2, and the second hose 22. Afterward, close the channel connecting the three-way valve 2 and the third hose 23, and the extraction conveyor 4 reverses its operation, delivering the smoke through the second hose 22, the three-way valve 2, and the first hose 21 into the smoking chamber 1. During the smoking process, if it is necessary to adjust the environment inside the smoking chamber 1, the side fan 102 can be activated to blow air into the chamber, and the exhaust fan 5 on the back can be opened to expel the smoke from the chamber.

[0040] In a specific embodiment, the cigarette-lighting chamber 3 includes a chamber cylinder 31, on which a cigarette insert 32 is installed for burning cigarettes. A third flexible hose 23 is connected to the cigarette insert 32. A dust collection seat 33 is threadedly connected to the bottom of the chamber cylinder 31. Multiple circumferentially arranged air inlets 34 are provided on the chamber cylinder 31. In use, the cigarette is fixed inside the chamber cylinder 31 by the cigarette insert 32, so that the cigarette burns stably inside the chamber cylinder 31. The dust collection seat 33 threadedly connected to the bottom of the chamber cylinder 31 can collect the soot produced by the burning cigarette, preventing soot from entering the subsequent pipeline and clogging the channel. At the same time, the multiple circumferentially arranged air inlets 34 on the chamber cylinder 31 can provide sufficient air for the burning of cigarettes, ensuring that the cigarette burns continuously and fully, and producing a stable amount of smoke.

[0041] In a specific embodiment, the cigarette insert 32 includes a hollow plug 321. The top of the chamber 31 has an insertion port, and the hollow plug 321 is inserted into the insertion port. The hollow plug 321 has a cavity inside. The bottom of the hollow plug 321 is connected to a plurality of annular array cigarette mouthpieces 323 located inside the chamber 31. The top of the hollow plug 321 is connected to a second connector 322. Both ends of the third hose 23 are connected to third plugs 231. The two third plugs 231 are respectively inserted and engaged with the corresponding ends of the second connector 322 and the three-way valve 2.

[0042] When in use, a lit cigarette is inserted into the mouthpieces 323 of the multiple annular array at the bottom of the hollow plug 321. The smoke produced by the burning cigarette enters the cavity of the hollow plug 321 and then flows out through the second connector 322 at the top of the hollow plug 321. The third plugs 231 at both ends of the third hose 23 are respectively connected to the second connector 322 and the corresponding ends of the three-way valve 2, so that the smoke can flow smoothly from the cigarette insert 32 into the third hose 23 and then into the subsequent components such as the three-way valve 2.

[0043] Multiple annular arrays of cigarette holders 323 can simultaneously hold multiple cigarettes, and the amount of smoke generated can be adjusted according to experimental needs, improving experimental efficiency. The plug-in design of the hollow plug 321 facilitates installation and disassembly, making it convenient to replace cigarettes or clean the cigarette holder 32. The plug-in cooperation between the third plug 231 and the second connector 322 and the three-way valve 2 ensures the sealing of the connection, prevents smoke leakage at the connection, ensures that the smoke is transported along the predetermined path, maintains stable smoke concentration, and improves the accuracy of experimental data.

[0044] In a specific embodiment, the smoke exhaust component 5 includes a smoke exhaust pipe 51, the back of the smoke chamber 1 is connected to the smoke exhaust pipe 51, and a valve 52 is installed on the smoke exhaust pipe 51.

[0045] When the smoking experiment needs to simulate the smoking situation in the natural environment, open the valve 52 on the exhaust pipe 51. At this time, the smoke in the smoking chamber 1 will be discharged to the outside through the exhaust pipe 51 under the action of the airflow generated by the fan 102. If there is no need to exhaust smoke, close the valve 52 to maintain the airtightness of the smoking chamber 1 and maintain the smoke concentration in the chamber.

[0046] The valve 52 can flexibly control the opening and closing of the smoke exhaust, making it convenient to adjust the amount and concentration of smoke in the smoke chamber 1 according to the experimental process, avoiding excessive accumulation of smoke in the chamber that could lead to the death of rats, ensuring the safety of experimental animals, and also allowing residual smoke to be discharged in time, facilitating subsequent cleaning of the smoke chamber 1 and its next use, thus improving the practicality and service life of the equipment.

[0047] In practical use, the exhaust pipe 51 can be connected to a purifier to prevent the smoke from polluting the environment.

[0048] In a specific embodiment, the front of the smoking box 1 is connected to a first connector 101 that communicates with its interior, and both ends of the first hose 21 are connected to a first plug 211. The two first plugs 211 are respectively inserted into the corresponding ends of the first connector 101 and the three-way valve 2.

[0049] In use, align the first plugs 211 at both ends of the first hose 21 with the corresponding ends of the first connector 101 and the three-way valve 2, and then insert them to make a connection. In this way, when the extraction conveyor 4 reverses the flow of flue gas, the flue gas can pass through the three-way valve 2, the first hose 21, and the first connector 101 to smoothly enter the smoke chamber 1, thus completing the conveying of flue gas to the smoke chamber 1.

[0050] The first plug 211 is connected to the first connector 101 and the three-way valve 2, which facilitates their installation and disassembly.

[0051] In a specific embodiment, the top of the smoking chamber 1 has an opening, and a sealing plug 103 is inserted into the opening. The opening at the top of the smoking chamber 1 is a channel for placing and removing rats. Before conducting the smoking experiment, the sealing plug 103 is pulled out, and the rat is placed into the smoking chamber 1 through the opening. Then, the sealing plug 103 is reinserted into the opening, so that a relatively sealed space is formed inside the smoking chamber 1. During the smoking process, the sealing plug 103 can prevent the smoke in the smoking chamber 1 from leaking from the top opening, ensuring that the smoke concentration in the smoking chamber 1 is stable. After the experiment, the sealing plug 103 is pulled out again, and the rat is taken out through the opening for subsequent testing.

[0052] The fumigation chamber 1 is made of acrylic sheet material and is transparent, making it easy for experimenters to observe the condition of the rats.

[0053] In a specific embodiment, the extraction and delivery component 4 is a suction pump 41. Both ends of the second hose 22 are connected to second plugs 221, which are respectively inserted into the air inlet of the suction pump 41 and the corresponding end of the three-way valve 2. The air outlet of the suction pump 41 is connected to a connecting pipe 411, and a bulb 412 is connected to the connecting pipe 411. During operation, when the suction pump 41 is started, a negative pressure is generated at the air inlet of the suction pump 41, causing the smoke in the cigarette lighter chamber 3 to pass through the suction pump 41 sequentially. The smoke is drawn into the suction pump 41 through the third hose 23, the three-way valve 2, and the second hose 22. Then, the smoke enters the connecting pipe 411 through the outlet of the suction pump 41 and is finally stored in the bulb 412. When it is necessary to deliver smoke to the smoking chamber 1, the suction pump 41 is adjusted to work in reverse. Under the action of the suction pump 41, the smoke in the bulb 412 is delivered to the smoking chamber 1 through the connecting pipe 411, the suction pump 41, the second hose 22, the three-way valve 2, and the first hose 21.

[0054] Example 2

[0055] The suction pump 41 is replaced with a manually controllable syringe 42 for easier operation, as detailed below:

[0056] The extraction and delivery component 4 is a syringe 42, and the injection head 421 on the syringe 42 is inserted into the second plug 221 at the end of the second hose 22 away from the three-way valve 2.

[0057] The syringe 42 has a piston inside, and a rod is installed on the piston. This is existing technology and will not be elaborated on further. Pulling the piston of the syringe 42 creates a negative pressure inside the syringe 42, which then draws smoke from the smoking chamber 3 through the second hose 22, the three-way valve 2, and the third hose 23. The smoke enters the syringe barrel of the syringe 42 for storage. When it is necessary to deliver smoke to the fumigation box 1, the piston of the syringe 42 is pushed, and the smoke in the syringe 42 is forced into the fumigation box 1 through the injection head 421, the second hose 22, the three-way valve 2, and the first hose 21.

[0058] The syringe 42 used above is simple to operate and has a low cost. It is suitable for experimental scenarios with small doses and precise control of flue gas usage. By controlling the pulling and pushing distance of the piston, the amount of flue gas extracted and delivered can be accurately controlled to meet the requirements of different experiments for flue gas concentration and usage. In addition, the syringe 42 is small in size, easy to carry and operate, and provides more options for experiments, especially suitable for small laboratories or experimental situations that require mobile operation.

[0059] The specific working principle of this utility model is as follows:

[0060] When in use, remove the hollow plug 321 from the chamber 31, insert the lit cigarette into the mouthpiece 323 of the annular array at the bottom of the hollow plug 321, and then reinsert the hollow plug 321 into the socket at the top of the chamber 31. At this time, the air inlet 34 on the chamber 31 provides oxygen for the cigarette to burn, the cigarette burns stably in the chamber 31, and the ash produced falls into the ash collection round seat 33 connected by the bottom thread.

[0061] Remove the sealing plug 103 from the top of the fumigation chamber 1, place the rat to be tested inside the fumigation chamber 1, and then reinsert the sealing plug 103 into the opening to ensure the airtightness of the fumigation chamber 1.

[0062] If the suction pump 41 is used, when the suction pump 41 is started, a negative pressure is generated at its air inlet. The smoke in the cigarette chamber 3 passes through the mouthpiece 323, the cavity of the hollow plug 321, the second connector 322, the third hose 23, the three-way valve 2, and the second hose 22 in sequence and is sucked into the suction pump 41. Then, it enters the connecting pipe 411 through the air outlet of the suction pump 41 and is finally stored in the bulb 412. If the syringe 42 is used, when the piston of the syringe 42 is pulled, the smoke is drawn from the cigarette chamber 3 through the injection head 421, the second hose 22, the three-way valve 2, and the third hose 23. The smoke enters the syringe 42.

[0063] Once sufficient smoke has been extracted, close the channel connecting the three-way valve 2 and the third hose 23. If a suction pump 41 is used, adjust it to work in reverse. The smoke in the bulb 412 is transported to the fumigation chamber 1 through the connecting pipe 411, suction pump 41, second hose 22, three-way valve 2, first hose 21, and first connector 101. If a syringe 42 is used, push the piston to force the smoke inside through the injection head 421, second hose 22, three-way valve 2, first hose 21, and first connector 101 into the fumigation chamber 1 to fumigate the rats inside. During the fumigation process, the fan 102 on the side of the fumigation chamber 1 can be activated to blow fresh air into the chamber, simulating a natural smoking environment, while preventing the rats from dying due to excessive smoke concentration.

[0064] Then, open the valve 52 on the exhaust pipe 51 of the exhaust component 5 on the back of the fumigation chamber 1. The smoke is discharged through the exhaust pipe 51 under the action of the fan 102. After the smoke is discharged, pull out the top sealing plug 103, take out the rat for subsequent testing. After that, disassemble all hoses and components, clean the soot in the ash collection round seat 33 in the smoke chamber 3 and the inside of the fumigation chamber 1 to prepare for the next experiment.

[0065] It should be understood that the above-described specific embodiments of this utility model are merely illustrative or explanatory of the principles of this utility model, and do not constitute a limitation thereof. Therefore, any modifications, equivalent substitutions, improvements, etc., made without departing from the spirit and scope of this utility model should be included within the protection scope of this utility model.

Claims

1. A rat fumigation device, characterized in that, It includes a smoke chamber (1), a three-way valve (2), a smoke-lighting chamber (3), and an extraction and conveying component (4); The three-way valve (2) is detachably connected to the three ends of the first hose (21), the second hose (22) and the third hose (23), respectively. The first hose (21) is detachably connected to the smoking box (1). The cigarette lighter compartment (3) is detachably connected to the third hose (23), and the cigarette lighter compartment (3) can be used for burning cigarettes; The extraction and conveying component (4) is detachably connected to the second hose (22) and is used to draw the smoke from the cigarette burning in the lighting chamber (3) into it through the third hose (23), the three-way valve (2) and the second hose (22), and then transport it to the smoking box (1) through the second hose (22), the three-way valve (2) and the first hose (21); The back of the smoking chamber (1) is connected to a smoke exhaust component (5) for venting smoke. The side of the smoking chamber (1) is connected to a fan (102) that blows air into it.

2. The rat fumigation device according to claim 1, characterized in that, The cigarette lighter compartment (3) includes a compartment (31), on which a cigarette insert (32) is installed to allow cigarettes to burn. The third flexible hose (23) is connected to the cigarette insert (32). A dust collection seat (33) is threaded to the bottom of the compartment (31). The compartment (31) has multiple circumferentially arranged air inlets (34).

3. The rat fumigation device according to claim 2, characterized in that, The cigarette insert (32) includes a hollow plug (321). The top of the chamber (31) is provided with an insertion port. The hollow plug (321) is inserted into the insertion port. The hollow plug (321) has a cavity inside. The bottom of the hollow plug (321) is connected to a plurality of annular array cigarette mouthpieces (323) located inside the chamber (31). The top of the hollow plug (321) is connected to a second connector (322). Both ends of the third hose (23) are connected to third plugs (231). The two third plugs (231) are respectively inserted and engaged with the second connector (322) and the corresponding end of the three-way valve (2).

4. The rat fumigation device according to claim 3, characterized in that, The smoke exhaust component (5) includes a smoke exhaust pipe (51), the back of the smoke chamber (1) is connected to the smoke exhaust pipe (51), and a valve (52) is installed on the smoke exhaust pipe (51).

5. The rat fumigation device according to claim 1, characterized in that, The front of the smoking box (1) is connected to a first connector (101) that communicates with its interior. Both ends of the first hose (21) are connected to a first plug (211). The two first plugs (211) are respectively inserted into the corresponding ends of the first connector (101) and the three-way valve (2).

6. The rat fumigation device according to claim 1, characterized in that, The top of the smoking box (1) has an opening, and a sealing plug (103) is inserted into the opening.

7. The rat fumigation device according to claim 1, characterized in that, The extraction and delivery component (4) is a suction pump (41). Both ends of the second hose (22) are connected to second plugs (221). The two second plugs (221) are respectively connected to the air inlet of the suction pump (41) and the corresponding end of the three-way valve (2). The air outlet of the suction pump (41) is connected to a connecting pipe (411), and a balloon (412) is connected to the connecting pipe (411).

8. The rat fumigation device according to claim 1, characterized in that, The extraction and delivery component (4) is a syringe (42), and the injection head (421) on the syringe (42) is connected to the second plug (221) at the end of the second hose (22) away from the three-way valve (2).

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