A nest for supporting multiple medical containers, a medical container pack containing this nest, and a method for manufacturing medical containers.

Abstract

The nest (1) according to the present invention comprises a plurality of breakable connecting bridges (10), a plurality of flanges (50) arranged in a predetermined pattern and configured to form flanges of a medical container (100), the flanges (50) being connected to the breakable connecting bridges (10), and a support structure (30) attached to the breakable connecting bridges (10) to support the flanges (50). The flanges (50) are integrally formed with the breakable connecting bridges (10) and the support structure (30).

Description

Technical Field

[0001] The present invention relates to a holding device for supporting a plurality of medical containers, a medical container pack including the holding device, and a method for manufacturing a medical container.

Background Art

[0002] In the present application, the distal end of a component or device should be understood to mean the end farthest from the user's hand, and the proximal end should be understood to mean the end closest to the user's hand. Similarly, in the present application, the "distal direction" should be understood to mean the direction of injection with respect to the medical container included in the packaging device of the present invention, and the "proximal direction" should be understood to mean the direction opposite to the above injection direction, that is, the direction toward the hand of the user holding the medical container with respect to the injection operation.

[0003] Medical containers such as pre-fillable syringes or prefilled syringes often need to be transported from one place to another, for example, from the manufacturing site to another place where a pharmaceutical composition such as a vaccine, drug or therapeutic agent can be filled into the medical container. Less frequently, the medical container may be manufactured and filled at the same initial location and then transported to a storage location. During transportation, the medical container is usually held by a holding device, also called a nest. The nest is placed in a box-shaped tub, and one opening is sealed with a sealing cover. To remove the medical container from this tub, basically, the sealing cover is peeled off, the nest holding the medical container is removed from the tub, and then the medical container is removed from the nest by sliding it axially with respect to the nest. Before being removed from the nest and individually packaged, the medical container is filled with a pharmaceutical composition by a filling machine.

[0004] A nest is a flat tray, typically configured to support 100 or more medical containers. A nest usually includes several holes aligned in a predetermined row, each hole configured to allow the insertion of one medical container barrel until the flange of the medical container rests on one side of the flat nest.

[0005] However, medical containers may shift slightly relative to their nests during transport or when the nests are processed on the filling line. As a result, medical containers may not be properly centered relative to the filling needle when filled with the pharmaceutical composition. Furthermore, syringe denesting can occur on the filling line. During transport, clearance involves impacts between adjacent containers, which may in some cases lead to cosmetic defects or damage to the containers.

[0006] Furthermore, medical containers such as syringes typically consist of an elongated barrel defining a reservoir for containing a pharmaceutical composition, a plunger stopper positioned within the barrel, a crimped needle and / or needle shield at the distal end of the barrel that moves the plunger stopper within the barrel, and a flange at the proximal end of the barrel that closes the tip. The flange provides a surface for the user's fingers, usually the index and middle fingers, while the plunger rod is operated by the thumb. Medical containers can be made of glass or plastic material.

[0007] In the manufacturing process of glass medical containers, a flange is formed in front of the tip. The flange then serves as support and a reference point during tip formation. However, the flange is not always perfectly flat. Therefore, inaccuracies can occur during tip formation. This can lead to increased dead volume or imperfect control of the syringe length. Dead volume should be understood as the amount of pharmaceutical composition remaining at the tip after the pharmaceutical composition has been transferred from the syringe to another device. Dead volume should be as small as possible, both to minimize waste of pharmaceutical composition and for the accuracy of the amount of pharmaceutical composition administered. [Overview of the project]

[0008] One aspect of the present invention is a holding device for supporting medical containers, which enables improved centering of medical containers on a filling line, thereby preventing medical containers from falling off or being damaged on the filling line or during transport, reducing dead volume, and better controlling the length of medical containers.

[0009] One aspect of the present invention is a holding device for holding a plurality of medical containers, Multiple breakable connecting bridges, A plurality of destructible flanges arranged in a predetermined pattern and configured to form a flange of a medical container, wherein the flanges are connected to a destructible connecting bridge, A retaining device comprising a support structure attached to a destructible connecting bridge for supporting multiple flanges.

[0010] Here, the flange is integrally formed with the destructible connecting bridge and support structure.

[0011] This holding device allows for improved centering of medical containers on the filling line because the flange of the medical container is attached to the support structure by a destructible connecting bridge. Since the flange is fixed to the support structure, it prevents the medical container from being subjected to impact during filling and transport.

[0012] The holding device may refer to a nest.

[0013] Advantageously, the destructible connecting bridge comprises a first end attached to one flange and a second end attached to another flange or support structure.

[0014] Advantageously, the first end has a thickness that decreases toward the flange.

[0015] Advantageously, the second end has a thickness that decreases toward the other flange or support structure.

[0016] These features ensure that the flange edges are smoothed after the connecting bridge is damaged.

[0017] Advantageously, the destructible connecting bridge includes an intermediate portion inserted between the first end and the second end.

[0018] The flange is preferably attached to the support structure by a destructible connecting bridge.

[0019] Advantageously, at least several adjacent flanges are separated from each other by only one or more destructible connecting bridges.

[0020] Therefore, these flanges are directly connected to adjacent flanges by at least one destructible connecting bridge.

[0021] This makes it possible to increase the number of flanges held by the retaining device per unit area.

[0022] In one embodiment, the support structure is a plate-like nest. The flange may also be plate-like. The flange and the nest can be on the same plane.

[0023] Advantageously, the support structure delimits a plurality of through openings, and each flange extends inside one of the through openings.

[0024] In one embodiment, each flange is surrounded by a segmented groove. Advantageously, each flange is surrounded by at least two slots, and two consecutive slots are separated by a breakable connection bridge. The slots extend between the support structure and the flange. Thus, the slots surrounding the flange form a segmented groove.

[0025] In one embodiment, each flange is connected to the support structure by at least two breakable connection bridges, preferably three, more preferably four breakable connection bridges. Thereby, the flange can be kept in a stable planar configuration.

[0026] In one embodiment, the support structure includes a peripheral edge, and the peripheral edge is connected to the peripheral flanges of a plurality of flanges by breakable connection bridges.

[0027] The peripheral edge enables handling of the holding device during filling or transportation while reinforcing the holding device to keep the flanges in the same plane.

[0028] In one embodiment, the support structure includes a reinforcing bar extending between adjacent rows of flanges.

[0029] Thereby, the support structure can be reinforced and maintained in a planar distribution, improving the accuracy of the filling line.

[0030] In one embodiment, a reinforcing bar extends beneath a destructible connecting bridge inserted between two rows of flanges. This allows the flanges to be held closer together, so the retainer can hold more flanges per unit area. More precisely, the reinforcing bar can be attached to the middle portion of the destructible connecting bridge.

[0031] Advantageously, the reinforcing bar is attached to the nest. The reinforcing bar extends to one side of the nest mentioned above.

[0032] Advantageously, the reinforcing bar is taller than it is wide.

[0033] The reinforcing bar may have a rectangular cross-sectional shape.

[0034] Advantageously, the support structure comprises a first set of reinforcing bars parallel to the first direction and a second set of reinforcing bars parallel to the second direction intersecting the first direction.

[0035] In one embodiment, the holding device includes a fixing means configured to secure one barrel of the medical container to a flange. This allows the medical container to be fixed to the holding device so that it cannot move on the filling line or during transport while the medical container is being formed.

[0036] In one embodiment, the fixing means includes guiding conduits extending from each flange, which are configured to receive the barrel. This allows for better centering of the filling line.

[0037] The guide conduit may include a fixing element configured to secure a barrel, for example, a barrel made of glass material, to the flange.

[0038] In an explicit manner: - The guide conduit has a mounting surface configured to receive adhesive to secure the barrel to the flange. - The guide conduit includes a friction-fit surface configured to secure the barrel to the flange. Advantageously, the friction-fit surface is made of thermoplastic elastomer or rubber. Advantageously, the guide conduit includes a ring attached to the flange, and the friction-fit surface is provided on the inner wall of this ring. Advantageously, this ring is inserted into a groove in the guide conduit. - The guide conduit includes clipping elements configured to fit into complementary clipping elements provided on the barrel.

[0039] Advantageously, each flange is equipped with an axial stop configured to block the insertion of the barrel into the guide conduit. This allows for precise positioning of the barrel.

[0040] Advantageously, the axial stop includes tapered sides, which allows for better centering of the filling line.

[0041] Another aspect of the present invention is a medical container pack comprising a holding device and a plurality of medical containers, the medical containers having glass barrels, the barrels being fixed to one of the flanges of the holding device.

[0042] As a result, each medical container is properly secured to the holding device, the centering of the filling line is improved, and it becomes possible to remove it from this support structure by destroying the corresponding connecting bridge.

[0043] Another aspect of the present invention is a medical container pack comprising a holding device and a plurality of medical containers, the medical containers having barrels made of plastic material, and the barrels and the holding device are molded as a single part. As a result, the barrels are formed integrally with the holding device. The barrels and the holding device are a single part.

[0044] Another aspect of the present invention is a method for manufacturing a medical container, - The steps described above involve preparing medical container packs, - The process includes the step of destroying a connecting bridge that secures one of the flanges to a support structure in order to remove the corresponding medical container from the medical container pack.

[0045] Advantageously, the method includes the steps of inserting a barrel into an opening in a flange and securing the barrel to the flange to form a medical container pack.

[0046] Advantageously, the method includes the step of forming barrels and flanges into a single part to form a medical container pack. Advantageously, the method includes the step of placing needles in a mold such that each barrel is overmolded onto one of the needles during the step of forming barrels and flanges into a single part. [Brief explanation of the drawing]

[0047] The present invention and the advantages arising therefrom will become apparent from the detailed description below with reference to the accompanying drawings. [Figure 1] This is a perspective view of a holding device according to one embodiment of the present invention. [Figure 2] This is a top view of a holding device according to one embodiment of the present invention. [Figure 3] This is a perspective view of a holding device according to one embodiment of the present invention. [Figure 4] This is a perspective view of a holding device according to one embodiment of the present invention. [Figure 5A] This is a top view of a part of a holding device according to one embodiment of the present invention. [Figure 5B] This is a cross-sectional view along line AA in Figure 5A. [Figure 6A] This is a partial cross-sectional view of a holding device according to a different embodiment of the present invention. [Figure 6B] This is a partial cross-sectional view of a holding device according to a different embodiment of the present invention. [Figure 6C] This is a partial cross-sectional view of a holding device according to a different embodiment of the present invention. [Figure 6D]This is a partial cross-sectional view of a holding device according to a different embodiment of the present invention. [Modes for carrying out the invention]

[0048] Referring to Figure 1, a holding device 1 according to the present invention is shown. The holding device 1 is configured to support a plurality of medical containers 100 simultaneously, as shown in Figure 4. Thus, the holding device 1 functions as a nest for packaging, storage, transport, and handling of medical containers 100 on a filling line. It should be noted that the medical containers 100 may be syringes, such as pre-fillable syringes. After filling, the medical containers 100 are intended to contain pharmaceutical compositions such as vaccines, pharmaceuticals, or therapeutic pharmaceutical compositions.

[0049] The holding device 1 comprises a plurality of destructible connecting bridges 10, a support structure 30, a destructible bridge 10 attached to the support structure 30, and a plurality of flanges 50 configured to form flanges 50 of the medical container 100, as will be described in more detail below.

[0050] The destructible connecting bridge 10 connects each flange 50 to another adjacent flange 50 or support structure 30, so that the flanges 50 are held together according to a predetermined pattern. As shown in Figure 2, the flanges 50 may be aligned in parallel rows. Furthermore, the flanges 50 preferably extend in the same plane, so that the retaining device has a substantially plate-like configuration.

[0051] The destructible connecting bridge 10 is configured to break or shatter when sufficient force is applied to it, allowing the flanges 50 to be separated from the support structure 30. As a result, the flanges 50 are connected to the connecting bridge 10 in a removable manner, and therefore to each other and / or to the support structure 30.

[0052] The flanges 50 are separated from the support structure 30 by a destructible connecting bridge 10. Thus, each flange 50 is attached to the retaining device 1 solely by the destructible connecting bridge 10.

[0053] As shown in Figure 2, each flange 50 is surrounded by a segmented groove 37. The groove 37 is a through-opening. The segmented groove 37 intersects with a destructible connecting bridge 10 configured to connect the flange 50 to the support frame 30. The groove 37 extends between the corresponding flange 50 and the support structure 30.

[0054] Each flange 50 may be surrounded by at least two slots 370, two consecutive slots 370 separated by a destructible connecting bridge 10. The slots 370 extend between the support structure 30 and the flange 50. Thus, the slots 370 surrounding the flange 50 form a segmented groove 37.

[0055] The support structure 30 is configured to maintain the flange 50 in a fixed position as long as the flange 50 is connected to the support structure 30 by a destructible connecting bridge 10. Thus, the support structure 30 forms a reinforcing means for fixedly supporting multiple flanges 50.

[0056] The support structure 30 connects all or at least some of the destructible connecting bridges 10. For example, it extends between adjacent connecting bridges 10, as shown in Figure 1, or extends above or below the connecting bridges 10, as shown in Figure 5B. As a result, each flange 50 may be connected to the support structure 30, or each flange 50 may be connected to an adjacent flange 50 by at least one of the destructible connecting bridges 10.

[0057] According to one preferred embodiment, the support frame 30 is a plate including a plurality of through-openings 36. At least one flange 50 extends into each through-opening 36, and the flange 50 is connected to the support frame 30 by at least two, preferably three, more preferably four, destructible connecting bridges 10. The plate is preferably rectangular.

[0058] The flange 50 is integrally formed with the destructible connecting bridge 10 and the support structure 30. In other words, the flange 50, the destructible connecting bridge 10, and the support structure 30 are a single component. As a result, the retaining device 1 is a nest with an integrated syringe flange 50.

[0059] Preferably, the flange 50, the destructible connecting bridge 10, and the support frame are made of a plastic material such as polypropylene. The flange 50, the destructible connecting bridge 10, and the support structure 30 are molded into a single piece.

[0060] The flange 50 is configured to function as the flange 50 of the medical container 100. The flange 50 may be plate-shaped. They may have two opposing planes 52, 54, namely a proximal surface 52 and a distal surface 54. The proximal surface 52 may function as a pressing surface for applying force to the flange 50 to break the connecting bridge 10 attached to this flange 50. Alternatively, this force may be applied to the distal surface 54. The distal surface 54 is configured to receive the user's fingers (generally the index and middle fingers) when the medical container 100 is in use. The proximal and distal surfaces 52, 54 are joined by a periphery 56. As seen in Figure 5B, the breakable connecting bridge 10 is preferably fixed to the edge 56 of the flange 50. The flange 50 demarcates a central opening 58. The central opening 58 is configured to receive the plunger rod of the medical container 100. The flange 50 preferably comprises two opposite arms 60 extending radially to provide a sufficient receiving area for the user's fingers. These two arms 60 may be joined by two opposite lateral portions 62. The lateral portions 62 are thinner than the arms 60 to improve the compactness of the flange 50, and as a result, the retaining device 1 contains more flange 50 per unit area.

[0061] The destructible connecting bridge 10 is configured to break in order to allow separation of the flanges 50. The destructible connecting bridge 10 may be a rod with one end fixed to one of the flanges 50 and the other end fixed to an adjacent flange 50 or support structure 30. Referring to Figure 5B, the destructible connecting bridge 10 may more precisely include a first end 12 attached to one of the flanges 50 and a second end 14 on the opposite side of the first end 12, the second end 14 being fixed to another flange 50 or support structure 30. The destructible connecting bridge 10 may also include an intermediate portion 16 connecting the first and second ends 12, 14. The first end 12 may have a tapering cross-section until it reaches the flange 50. Similarly, the second end 14 may have a tapering cross-section until it reaches the other flange 50 or support structure 30. The first end 12 and the second end 14 each have vertices 13 and 15, respectively. These vertices 13 and 15 are the thinnest parts of the bridge 10 and may be the only parts of the connecting bridge 10 that contact the flange 50 or the support structure 30. The vertices 13 and 15 may be point or line contact, more precisely, linear contact. As shown in Figures 5A and 5B, this line contact preferably extends parallel to the rows of flange 50. The first and / or second ends 12 and 14 may have a conical or pyramidal shape. The intermediate section 16 may have a cross-section greater than or equal to the maximum cross-section of the first or second end 12 and 14. This intermediate section 16 may have a cylindrical or parallelepiped shape. As shown in Figures 5A and 5B, the intermediate section 16 has a proximal face 160 and a distal face 162.

[0062] Note that the destructible connecting bridge 10 can extend longitudinally perpendicular or parallel to the rows of flanges 50, as shown in Figure 2 where the destructible connecting bridge 10 is positioned vertically or horizontally.

[0063] Referring to Figure 2, each flange 50 may be connected to an adjacent flange 50 or support structure 30 by two pairs of destructible connecting bridges 10. These two pairs include a first pair of connecting bridges 10a parallel to a first direction, and a second pair of connecting bridges 10b parallel to a second direction perpendicular to the first direction. More precisely, the first and second directions are parallel to the orthogonal rows of flanges 50.

[0064] The support structure 30 is configured to hold the flanges 50 together and to be fixed to each other. As described above, the support structure 30 may be plate-shaped. More precisely, the support structure 30 has a rectangular plate shape. As shown in the figure, the support structure 30 may include a perimeter 32 surrounding the flanges 50. This perimeter 32 has one or more longitudinal beams or plate-shaped bands 320, each lining one side of a plurality of flanges 50 that can be connected to each other at corners. The perimeter 32 is connected to a pair of outer circumferential flanges 50a by a breakable connecting bridge 10. The outer circumferential flanges 50a are the outermost flanges 50 of the plurality of flanges 50.

[0065] The support structure 30 may include reinforcing bars 34 extending between adjacent rows of flanges 50. The reinforcing bars 34 preferably have two opposing ends 340 fixed to the periphery 32. The reinforcing bars 34 preferably extend linearly. As seen in Figure 5B, the reinforcing bars 34 advantageously have a rectangular cross-section. Their height h may be greater than their width w.

[0066] As described above, the support structure 30 can divide a plurality of openings 36, each opening 36 receiving at least one flange 50. As shown in Figure 5A, the openings 36 can be divided by adjacent reinforcing bars 34. Referring to Figures 1 to 4, each opening 36 receives only one flange 50. Referring to Figure 5A, each opening 36 receives an entire row of flanges 50 or a portion of a row of flanges 50.

[0067] In embodiments not shown, the reinforcing bar 34 may extend to one side of the plate-shaped nest that forms the support structure 30 shown in Figures 1 to 4.

[0068] As shown in Figure 5B, the reinforcing bar 34 can instead be fixed to the intermediate portion 16 of the connecting bridge 10 that directly connects two adjacent rows of flange 50. For example, the reinforcing bar 34 extends over or preferably below these destructible connecting bridges 10, i.e., to the proximal or distal surface 160 or 162 of the destructible connecting bridges 10.

[0069] The flange 50 is advantageously provided with fastening means configured to secure one barrel 102 of the medical container 100 to each flange 50. Referring to Figure 3, the fastening means preferably comprises a guide conduit 72. The guide conduit 72 extends from the opening 58. The guide conduit 72 is configured to receive and guide the insertion of the barrel 102 into the opening 58, which occurs in a direction perpendicular to the flange 50. The guide conduit 72 is tubular, for example, having a cylindrical shape. Preferably, the guide conduit 72 extends from the distal surface 54 of the flange 50. The guide conduit 70 defines an inner wall 74. The inner wall 74 may include an annular recess or groove 740 configured to receive a fastening element 76 for securing the barrel 102 to the flange 50. The sleeve 70 can be molded integrally with the flange 50.

[0070] Referring to Figure 6A, the fixing element 76 may be an adhesive applied to the surface 742 of the groove 740. Thus, the surface 742 forms a mounting surface configured to receive the adhesive. As a result, the barrel 102 can be bonded to the guide conduit 72.

[0071] Referring to Figure 6B, the fixing element 76 may be an internal friction mating surface 760 configured to adhere to the barrel 102. This friction mating surface 760 and the barrel 102 have an adhesion coefficient greater than the adhesion coefficient between the rest of the guide conduit 72 and the barrel 102. This friction mating surface 760a may be housed inside an insert, for example, a recess or groove 740, and positioned on a ring made of thermoplastic elastomer or rubber. Alternatively, the friction mating surface 760 may be made of thermoplastic elastomer realized by co-injection molding.

[0072] Referring to Figure 6C, the fixing element 76 may have a snap function. The snap feature may be an annular rib provided on the side wall of the barrel 102. This rib has a shape complementary to the shape of the groove 740 and is configured to be inserted into the groove 740 in order to fix the barrel 102 to the flange 50. Thus, the rib and groove 740 form a clipping element configured to fix the barrel 102 to the flange 50.

[0073] The fixing means may include, for example, an axial stop configured to block the insertion of the barrel 102 through the flange 50 after the barrel 102 has been fully inserted. The axial stop may be a tapered side surface 64 provided on the inner edge that demarcates the opening 58. The barrel 102 may include a proximal end with a tapered side surface 1020 configured to be inclined with respect to the surface 64 when the barrel 102 is introduced into the opening 58.

[0074] Referring to Figure 4, a pack of medical containers is shown, including a holding device 1 and a plurality of medical containers 100. These medical containers 100 are secured to flanges 50 which are fixed to a nest in a removable manner. The medical container 100 has a barrel 102 defining a reservoir for a pharmaceutical composition, the barrel 102 having a proximal end attached to one of the flanges 50 and a distal end with a distal tip, the distal tip defining a fluid passage communicating with the reservoir. In one embodiment, the barrel 102 is made of glass and is fixed to the corresponding flange 50 by fastening means. In another embodiment, the barrel 102 is made of a plastic material, and the flanges 50, support structure 30, and a breakable connecting bridge are molded as a single piece, as shown in Figure 6D. The medical container 100 may also include a needle 103 attached to the distal tip and a cap protecting the needle. The medical container pack may be overmolded onto the needle. Furthermore, the plunger stopper can be positioned inside the barrel and connected to a plunger that extends outside the barrel 102.

[0075] The present invention also relates to a method for manufacturing a plurality of medical containers 100, and this method is - The steps described above involve preparing medical container packs, - The procedure includes the step of destroying the connecting bridge 10 that secures the flange 50 to the support structure 30 in order to remove the medical container 100 from the medical container pack.

[0076] This step is preferably performed after the barrel 102 is secured to the flange 50, and more precisely, after the filling step in which the pharmaceutical composition is poured into the barrel 102.

[0077] The step of destroying the connecting bridge 10 can be achieved by applying distal or proximal force to the flange 50 or the support structure 30. The step of destroying the connecting bridge 10 can also be achieved by applying a cutting die to the destructible connecting bridge 10 or support structure 30.

[0078] The step of preparing the medical container pack may include the step of securing the barrel 102 of the medical container 100 to the flange 50 of the holding device 1.

[0079] The method may advantageously include the step of inserting the barrel 102 into the opening 58 of the flange 50 before fixing the barrel 102 to the flange 50 with fixing means. Preferably, the barrel 102 is made of glass.

[0080] In one embodiment, the step of fixing the barrel 102 to the flange 50 includes the step of molding the barrel 102 and the flange 50 into a single part. Prior to this step, the needle 103 can be positioned in the mold so that the barrel 102 is overmolded onto the needle 103.

Claims

1. A nest (1) for supporting multiple medical containers (100), wherein the nest (1) is Multiple destructible connecting bridges (10), A plurality of flanges (50) arranged in a predetermined pattern and configured to form a flange of the medical container (100), wherein the flanges (50) are connected to the destructible connecting bridge (10), and the flanges (50) have a proximal surface (52) configured to form a pressing surface for applying force to the flange to destruct the connecting bridge (10), a distal surface (54) opposite to the proximal surface (52), and an opening (58) for inserting a barrel (102) of the medical container (100) separate from the flanges (50), wherein the distal surface (54) is configured to receive a user's finger during use of the medical container, The system comprises a plate-shaped support structure (30) attached to the destructible connecting bridge (10) to support the plurality of flanges (50), The flange (50), the destructible connecting bridge (10), and the support structure (30) are molded into a single part such that the flange (50) is integrally formed with the destructible connecting bridge (10) and the support structure (30). The nest (1) is characterized in that each flange (50) is provided with fixing means configured to fix one of the barrels (102) of the medical container (100) to the flange (50).

2. The nest (1) according to claim 1, characterized in that each flange (50) is surrounded by a groove (37) whose circumference is composed of multiple parts.

3. The nest (1) according to claim 1 or 2, characterized in that each flange (50) is connected to the support structure (30) by at least two of the destructible connecting bridges (10), preferably three, more preferably four of the destructible connecting bridges (10).

4. The nest (1) according to any one of claims 1 to 3, characterized in that the support structure (30) comprises a periphery (32), the periphery (32) is connected to the outer circumferential flanges (50a) of the plurality of flanges (50) by a destructible connecting bridge (10).

5. The nest (1) according to any one of claims 1 to 4, characterized in that the support structure (30) comprises a reinforcing bar (34) extending between adjacent rows of flanges (50).

6. The nest (1) according to claim 5, characterized in that the reinforcing bar (34) extends below the destructible connecting bridge (10).

7. The nest (1) according to any one of claims 1 to 6, characterized in that the fixing means comprises guide conduits (72) extending from each flange (50), and the guide conduits (72) are configured to receive the barrel (102).

8. The nest (1) according to any one of claims 1 to 7, characterized in that the fixing means comprises a mounting surface (742) configured to receive an adhesive so as to fix the barrel to the flange (50).

9. The nest (1) according to any one of claims 1 to 7, characterized in that the fixing means comprises a friction fitting surface (760) configured to fix the barrel (102) to the flange (50).

10. The nest (1) according to any one of claims 1 to 7, characterized in that the fixing means comprises a clipping element (740) configured to fit with a complementary clipping element (76) provided on the barrel (102).

11. A medical container pack (1, 100) comprising a nest (1) according to any one of claims 1 to 10 and a plurality of medical containers (100), wherein the plurality of medical containers (100) have glass barrels (102), and the barrels (102) are fixed to one of the flanges (50).

12. A method for manufacturing a medical container (100), The steps of preparing the medical container pack (1,100) according to claim 11, The steps include: destroying the connecting bridge (10) that secures one of the flanges (50) to the support structure (30) in order to remove the corresponding medical container (100) from the medical container pack (1, 100); A manufacturing method characterized by including the following.

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