Traditional Chinese medicine extract drying method for preparing drug for curing osteoporosis

Abstract

The invention is a traditional Chinese extract drying method for preparing a drug for curing osteoporosis, which comprises the following steps of drying extract obtained by prescribing and extracting through a micro-wave vacuum drying sterilizer, spreading extract in a baking plate according to 3-5kg per baking plate, and drying under the conditions that the material temperature of the micro-wave vacuum drying sterilizer is set as 80-100 DEG C, the running time is 80-120min, and the vacuum degree is controlled at minus 0.08-minus 0.09MPa. The dried extract obtained by the method can effectively overcome the defects of decomposed thermal sensitivity component, reduced effective component content, high labor intensity, large thermal quantity consumption, lower thermal efficiency, hardened caked masses of materials, difficult crushing and the like caused by long-time high-temperature baking in vacuum tank drying method; the dried extract has the advantages of maintained fragrance of medicinal materials, moderate color, loose texture, easy crushing, low moisture, convenient preparation processing and product storage, good dissolubility in water and alcohol, less insoluble impurities, high content of effective components and good product quality.

Description

[technical field]

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a drying method for extracting extracts from traditional Chinese medicines for treating osteoporosis. [Background technique]

[0002] In the preparation of traditional Chinese medicine for treating osteoporosis, drying the extract extracted from traditional Chinese medicine is an important link in the production. In the applicant’s pre-patent ZL200610021928.3, titled “Drugs for Treating Osteoporosis and Preparation Method thereof”, the extract was dried in a vacuum box. It was found in the drying production of the extract that the heating tube in the box oven The outer wall is covered with a layer of white needle-like crystals, which have been identified as the active ingredient psoralen. Relevant data show that psoralen is sublimable, and it has been separated out from the extract after being baked at high temperature for a long time, thus af...

Examples

Embodiment 1

[0027] (1). Ingredients: 583.5 parts by weight of psoralen; 583.5 parts by weight of Herba Epiphyllum; 417 parts by weight of medlar; 417 parts by weight of Ligustrum lucidum; parts by weight.

[0028] (2). According to the above-mentioned dosage and ratio of the seven medicinal materials, drynariae are scalded.

[0029] (3). Soak psoraleae and privet fruit in an ethanol solution with a concentration of 80% for about 2 hours, reflux and extract twice at 80°C, and add 10 times the concentration of the medicinal materials for the first time to 80% Extract with ethanol solution for 2.5 hours, add 8 times the concentration of medicinal materials for the second time and extract with 80% ethanol solution for 2 hours, combine the two alcohol extracts, reclaim ethanol at 70~80°C and concentrate to a relative density of 1.35~1.40g / ml ( 80~90℃) extract A, set aside.

[0030] (4). Combine the five herbs of Epimedium, Lycium barbarum, Rhizoma Drynariae, Gouji, and Achyranthes bidentata ...

Embodiment 2

[0033] (1). Ingredients: 583.5 parts by weight of psoralen; 583.5 parts by weight of Herba Epiphyllum; 417 parts by weight of medlar; 417 parts by weight of Ligustrum lucidum; parts by weight.

[0034] (2). Weigh the Qiwei herbs according to the prescription, and scald the Rhizoma Rhizoma Rhizoma Rhizome.

[0035] (3). Soak the medicinal materials Psoralen and Ligustrum lucidum in 75% ethanol solution for about 4 hours, reflux extraction at 82°C twice, add 10 times the medicinal materials for the first time and extract 2.5% in 75% ethanol solution hour, the second time add 8 times the concentration of the medicinal material and extract with 75% ethanol solution for 2 hours, combine the alcohol extract, reclaim the ethanol and concentrate it to the extract A with a relative density of 1.35~1.40 ((80~90°C measurement)), set aside .

[0036] (4). Combine the five medicinal materials of Epimedium, Lycium barbarum, Drynaria tangensis, Gouji, and Achyranthes bidentata, with the dr...

[technical field]

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a drying method for extracting extracts from traditional Chinese medicines for treating osteoporosis. [Background technique]

[0002] In the preparation of traditional Chinese medicine for treating osteoporosis, drying the extract extracted from traditional Chinese medicine is an important link in the production. In the applicant’s pre-patent ZL200610021928.3, titled “Drugs for Treating Osteoporosis and Preparation Method thereof”, the extract was dried in a vacuum box. It was found in the drying production of the extract that the heating tube in the box oven The outer wall is covered with a layer of white needle-like crystals, which have been identified as the active ingredient psoralen. Relevant data show that psoralen is sublimable, and it has been separated out from the extract after being baked at high temperature for a long time, thus af...

Examples

Embodiment 1

[0027] (1). Ingredients: 583.5 parts by weight of psoralen; 583.5 parts by weight of Herba Epiphyllum; 417 parts by weight of medlar; 417 parts by weight of Ligustrum lucidum; parts by weight.

[0028] (2). According to the above-mentioned dosage and ratio of the seven medicinal materials, drynariae are scalded.

[0029] (3). Soak psoraleae and privet fruit in an ethanol solution with a concentration of 80% for about 2 hours, reflux and extract twice at 80°C, and add 10 times the concentration of the medicinal materials for the first time to 80% Extract with ethanol solution for 2.5 hours, add 8 times the concentration of medicinal materials for the second time and extract with 80% ethanol solution for 2 hours, combine the two alcohol extracts, reclaim ethanol at 70~80°C and concentrate to a relative density of 1.35~1.40g / ml ( 80~90℃) extract A, set aside.

[0030] (4). Combine the five herbs of Epimedium, Lycium barbarum, Rhizoma Drynariae, Gouji, and Achyranthes bidentata ...

Embodiment 2

[0033] (1). Ingredients: 583.5 parts by weight of psoralen; 583.5 parts by weight of Herba Epiphyllum; 417 parts by weight of medlar; 417 parts by weight of Ligustrum lucidum; parts by weight.

[0034] (2). Weigh the Qiwei herbs according to the prescription, and scald the Rhizoma Rhizoma Rhizoma Rhizome.

[0035] (3). Soak the medicinal materials Psoralen and Ligustrum lucidum in 75% ethanol solution for about 4 hours, reflux extraction at 82°C twice, add 10 times the medicinal materials for the first time and extract 2.5% in 75% ethanol solution hour, the second time add 8 times the concentration of the medicinal material and extract with 75% ethanol solution for 2 hours, combine the alcohol extract, reclaim the ethanol and concentrate it to the extract A with a relative density of 1.35~1.40 ((80~90°C measurement)), set aside .

[0036] (4). Combine the five medicinal materials of Epimedium, Lycium barbarum, Drynaria tangensis, Gouji, and Achyranthes bidentata, with the dr...

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