A high-precision photodynamic therapy device

Abstract

The present invention discloses a high-precision photodynamic therapy device. The photodynamic therapy device includes a laser irradiator, which includes: a housing. An irradiation light source, which is arranged in the housing, and the irradiation light source can generate a therapeutic light with a first wavelength to irradiate the surface to be irradiated. A plurality of ranging light sources, which are arranged in the housing, and the plurality of ranging light sources can generate a plurality of ranging light with a second wavelength, and the plurality of ranging light can converge into a laser spot on the surface to be irradiated at a preset irradiation distance. A plurality of positioning light sources, which are arranged in the housing, and the plurality of positioning light sources can generate a plurality of positioning light with a third wavelength, and the plurality of positioning light can generate a plurality of straight line projections on the surface to be irradiated, and the plurality of straight line projections intersect at least two by two to form an irradiation area. Among them, the plurality of positioning light sources are arranged along the edge of the irradiation light source. The present invention can keep the distance between the surface to be irradiated and the laser irradiator correct and stable.

Description

Technical Field

[0001] The invention relates to the field of photodynamic therapy, and in particular to a high-precision photodynamic therapy device. Background Art

[0002] Photodynamic therapy is a new method of treating diseases using photosensitizing drugs and laser activation.

[0003] Photodynamic therapy includes three steps: administering photosensitizers, applying light of corresponding wavelengths, and avoiding light to wait for the metabolism of photosensitizers.

[0004] Among them, when applying light of the corresponding wavelength, it is necessary to select the most appropriate light intensity according to the different photosensitizers and indications, and irradiate the lesion at a pre-set irradiation distance. To ensure that the light intensity is appropriate and constant, it is necessary to keep the distance between the irradiation light source and the skin of the lesion appropriate and stable.

[0005] Furthermore, when irradiating the lesion, the irradiation area of ​​the laser irradiator needs to be aligned with the lesion in order to achieve the treatment effect.

[0006] The existing photodynamic therapy device is not provided with a control module for controlling the irradiation distance, and is not provided with a device that can facilitate the alignment of the irradiation area with the lesion site, which causes inconvenience during use, and is easy to irradiate at a wrong irradiation distance, thus failing to achieve a good treatment effect.

[0007] Therefore, it is necessary to further improve the existing photodynamic therapy device so that it can facilitate the adjustment of the irradiation distance and the alignment of the lesion site. Summary of the invention

[0008] In order to overcome the defects in the prior art, the present invention provides a high-precision photodynamic therapy device, which can keep the distance between the surface to be irradiated and the laser irradiator correct and stable during the treatment process.

[0009] The present invention discloses a high-precision photodynamic therapy device, characterized in that it comprises a laser irradiator, wherein the laser irradiator comprises:

[0010] shell;

[0011] an irradiation light source disposed in the housing, the irradiation light source being capable of generating a therapeutic light having a first wavelength to irradiate a surface to be irradiated;

[0012] a plurality of ranging light sources, which are disposed in the housing, the plurality of ranging light sources can generate a plurality of ranging light rays having a second wavelength, and the plurality of ranging light rays can converge into a laser spot on the surface to be irradiated at a preset irradiation distance; and

[0013] A plurality of positioning light sources are arranged in the housing, the plurality of positioning light sources can generate a plurality of positioning light rays having a third wavelength, the plurality of positioning light rays can generate a plurality of straight line projections on the surface to be irradiated, and the plurality of straight line projections at least intersect in pairs to form an irradiation area;

[0014] Wherein, a plurality of the positioning light sources are arranged along the edge of the irradiation light source, so that the treatment light can be arranged within the irradiation area.

[0015] Preferably, the laser irradiator includes three ranging light sources, which can generate three ranging lights having the second wavelength, and the three ranging lights can converge into a laser spot on the surface to be irradiated at the preset irradiation distance when the surface to be irradiated is parallel to the surface of the laser irradiator.

[0016] Preferably, the laser irradiator includes at least three positioning light sources.

[0017] Further preferably, the laser irradiator comprises four positioning light sources, and the four positioning light sources are arranged around the edge of the irradiation light source and can form a rectangular irradiation area on the surface to be irradiated.

[0018] Preferably, the high-precision photodynamic therapy device further comprises a chassis and an adjustment rod, and the laser irradiator is connected to the chassis via the adjustment rod.

[0019] Further preferably, a controller is provided in the chassis to set the preset irradiation distance and irradiation time, and the laser irradiator is electrically connected to the controller.

[0020] The beneficial effects of the present invention are as follows:

[0021] The high-precision photodynamic therapy device of the present invention is provided with three ranging light sources. The three ranging light sources can generate three ranging light rays with a second wavelength. The three ranging light rays can converge into a laser spot on the surface to be irradiated at a preset irradiation distance when the surface to be irradiated is parallel to the surface of the laser irradiator. Thus, the distance between the surface to be irradiated and the laser irradiator can be kept correct and stable during the treatment process. For the treatment of skin lesions with a larger area, the parallelism of the surface to be irradiated and the surface of the laser irradiator can ensure that the light intensity of the irradiation light source received by each position of the skin lesions is uniform, thereby improving the treatment effect.

[0022] The high-precision photodynamic therapy device of the present invention is provided with four positioning light sources, and the four positioning light sources can generate four positioning light rays with a third wavelength. The four positioning light rays can generate four straight line projections on the surface to be irradiated, and the four straight line projections intersect each other to form a rectangular irradiation area on the surface to be irradiated. The four positioning light sources are arranged around the edge of the irradiation light source, so that the treatment light rays can be set within the irradiation area. Therefore, in the process of using the photodynamic therapy device for treatment, as long as the lesion site is ensured to be within the rectangular irradiation area, a better treatment effect can be guaranteed.

[0023] In order to make the above and other purposes, features and advantages of the present invention more obvious and easy to understand, preferred embodiments are specifically cited below and described in detail with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0025] Figure 1 is a schematic structural diagram of a high-precision photodynamic therapy device in an embodiment of the present invention;

[0026] Figure 2 is a working principle diagram of a high-precision photodynamic therapy device in an embodiment of the present invention;

[0027] Figure 3 is a working principle diagram of the high-precision photodynamic therapy device in an embodiment of the present invention when the device is not within the preset irradiation distance range;

[0028] Figure 4 is a working principle diagram of the high-precision photodynamic therapy device in an embodiment of the present invention that does not correspond to the lesion site;

[0029] The figure markings of the above figures are: 1-chassis; 2-adjusting rod; 3-laser irradiator; 4-pulley; 5-laser spot; 6-linear projection; 7-irradiation area; 8-lesion site. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Reference Figures 1 to 4 This embodiment provides a high-precision photodynamic therapy device, including a laser irradiator 3, wherein the laser irradiator 3 includes:

[0032] shell;

[0033] an irradiation light source disposed in the housing, the irradiation light source being capable of generating a therapeutic light having a first wavelength to irradiate a surface to be irradiated;

[0034] a plurality of ranging light sources, which are arranged in the housing, the plurality of ranging light sources can generate a plurality of ranging light rays having a second wavelength, and the plurality of ranging light rays can converge into a laser spot 5 on the surface to be irradiated at a preset irradiation distance; and

[0035] A plurality of positioning light sources, which are arranged in the housing, the plurality of positioning light sources can generate a plurality of positioning light rays having a third wavelength, the plurality of positioning light rays can generate a plurality of straight line projections 6 on the surface to be irradiated, and the plurality of straight line projections 6 intersect at least two by two to form an irradiation area 7;

[0036] Wherein, a plurality of the positioning light sources are arranged along the edge of the irradiation light source, so that the treatment light can be set within the irradiation area 7.

[0037] This embodiment provides a high-precision photodynamic therapy device for irradiating the surface of a lesion site 8 at a preset irradiation distance. The surface of the lesion site 8 is the surface to be irradiated.

[0038] Key reference Figure 1 The high-precision photodynamic therapy device includes a laser irradiator 3, a chassis 1, and an adjustment rod 2. A controller is provided in the chassis 1, and the laser irradiator 3 is electrically connected to the controller, so that the controller can control the preset irradiation distance, irradiation time, irradiation light source wavelength, and light intensity of the irradiation light source.

[0039] The laser irradiator 3 is connected to the chassis 1 through the adjustment rod 2, and the adjustment rod 2 can move left and right and up and down to adjust the direction and angle of the laser irradiator 3, so as to facilitate use. A control screen is set on the surface of the chassis 1, and the control screen controls the operation of the photodynamic therapy device based on user operation. The position of the laser irradiator 3 can be adjusted according to the program pre-written in the controller, or the required parameters can be input into the controller in the chassis 1 through the control screen, so that the operator can adjust it according to the needs of each use. Four pulleys 4 are also set at the bottom of the chassis 1 to facilitate the operator to move the photodynamic therapy device.

[0040] The laser irradiator 3 includes a housing, an irradiation light source, a plurality of distance measuring light sources, and a plurality of positioning light sources.

[0041] The housing is in a rectangular shape. One end of the housing is connected to the adjustment rod 2. The other end of the housing is a glass surface to allow light to pass through. Two handles are also provided on the two side walls of the housing to facilitate the movement of the laser irradiator 3, thereby facilitating the adjustment of the position of the laser irradiator 3. A housing cavity is provided inside the housing to accommodate an irradiation light source, a plurality of ranging light sources, and a plurality of positioning light sources.

[0042] The irradiation light source is arranged in the internal accommodating cavity of the housing. The irradiation light source can generate therapeutic light with a first wavelength, and the first wavelength is set according to the type of photosensitizer used and the wavelength required for different indications. The therapeutic light can irradiate the surface to be irradiated, that is, irradiate the lesion site 8. The light intensity of the irradiation light source has an important influence on the therapeutic effect of the lesion site 8. The light intensity and the irradiation distance are closely related. If the irradiation distance is too large, the light intensity will not reach the preset value. If the irradiation distance is too small, the light intensity will exceed the preset value, thereby causing the irradiation light source to have a poor therapeutic effect on the lesion site 8.

[0043] Therefore, in order to improve the irradiation effect of the irradiation light source on the lesion site 8, the light intensity of the irradiation light source during the treatment process must be appropriate and stable, so that the accuracy of the irradiation distance value between the irradiation light source and the surface to be irradiated must be ensured, that is, the irradiation distance between the irradiation light source and the surface to be irradiated must be equal to the preset irradiation distance, which is set according to the type of photosensitizer and the requirements of different indications.

[0044] Based on this, this embodiment is provided with three ranging light sources, and the three ranging light sources are arranged in the housing. The three ranging light sources can respectively generate three ranging lights with the second wavelength. Figure 3 When the distance between the surface to be irradiated and the laser irradiator 3 is less than or greater than the preset irradiation distance, three ranging lights will generate three light spots on the surface to be irradiated to remind the operator to readjust the distance between the laser irradiator 3 and the surface to be irradiated.

[0045] Key reference Figure 2 According to the principle of 3 points determining 1 plane, it can be known that only when the distance between the surface to be irradiated and the laser irradiator 3 is the preset irradiation distance, and the surface to be irradiated is parallel to the surface of the laser irradiator 3, the three ranging lights can converge into a laser spot 5 on the surface to be irradiated at the preset irradiation distance, so that the distance between the surface to be irradiated and the laser irradiator 3 can be kept correct and stable during the treatment process. For the treatment of skin lesions with a larger area, the parallelism between the surface to be irradiated and the surface of the laser irradiator 3 can ensure that the light intensity of the irradiated light source at each position of the skin lesions is uniform, thereby improving the treatment effect.

[0046] In another optional embodiment, two ranging light sources are provided. The two ranging light sources are provided in the housing. The two ranging light sources can respectively generate two ranging light rays having a second wavelength. When the distance between the surface to be irradiated and the laser irradiator 3 is less than or greater than the preset irradiation distance, the two ranging light rays will generate two light spots on the surface to be irradiated to remind the operator to readjust the distance between the laser irradiator 3 and the surface to be irradiated. The provision of two ranging light sources is relatively simple when adjusting the position of the laser irradiator 3. During the treatment process using the photodynamic therapy device, as long as there is always only one laser light spot 5 at the lesion site 8, it means that the distance between the surface to be irradiated and the laser irradiator 3 is correct and stable. However, it cannot be guaranteed that the surface to be irradiated and the laser irradiator 3 are parallel.

[0047] In another optional embodiment, four ranging light sources are provided. The four ranging light sources are arranged in the housing. The four ranging light sources can respectively generate four ranging light rays having a second wavelength. When the distance between the surface to be irradiated and the laser irradiator 3 is less than or greater than the preset irradiation distance, the four ranging light rays will generate four light spots on the surface to be irradiated to remind the operator to readjust the distance between the laser irradiator 3 and the surface to be irradiated. The four ranging light rays can converge into a laser light spot 5 on the surface to be irradiated at the preset irradiation distance only when and only when the distance between the surface to be irradiated and the laser irradiator 3 is the preset irradiation distance, and the surface to be irradiated is parallel to the surface of the laser irradiator 3.

[0048] When irradiating the lesion 8, the irradiation area 7 of the laser irradiator 3 needs to be aligned with the lesion 8 to achieve the treatment effect. Figure 2 In this embodiment, four positioning light sources are provided. The four positioning light sources are arranged in the outer shell. The four positioning light sources are arranged around the edge of the irradiation light source, so that the therapeutic light can be set within the irradiation area 7. The four positioning light sources can generate four positioning light rays with a third wavelength. The four positioning light rays can generate four straight line projections 6 on the surface to be irradiated, and the four straight line projections 6 intersect in pairs to form a rectangular irradiation area 7 on the surface to be irradiated. In the process of using the photodynamic therapy device for treatment, as long as the lesion site 8 is ensured to be within the rectangular irradiation area 7, a better treatment effect can be guaranteed. Please refer to the attached drawings for details. Figure 4 When the irradiation area 7 of the laser irradiator 3 does not correspond to the lesion site 8 , the four positioning rays cannot generate a rectangular irradiation area 7 on the lesion site 8 .

[0049] In another optional embodiment, the laser irradiator 3 is provided with three positioning light sources. The three positioning light sources are arranged in the housing. The three positioning light sources are arranged along the edge of the irradiation light source, so that the therapeutic light can be arranged within the irradiation area 7. The three positioning light sources can generate three positioning light rays with a third wavelength. The three positioning light rays can generate three straight line projections 6 on the surface to be irradiated, and the three straight line projections 6 intersect each other to form a triangular irradiation area 7 on the surface to be irradiated. In the process of using the photodynamic therapy device for treatment, as long as the lesion site 8 is ensured to be within the triangular irradiation area 7, a better treatment effect can be guaranteed.

[0050] The method of using the high-precision photodynamic therapy device of this embodiment is as follows:

[0051] A photosensitizer is administered to the lesion site 8 .

[0052] After the photosensitizer is applied to the lesion site 8 , a rectangular irradiation area 7 formed by four straight line projections 6 respectively generated by four positioning light sources corresponds to the lesion site 8 .

[0053] After the lesion site 8 is in the irradiation area 7 , the three ranging lights generated by the three ranging light sources converge into a laser spot 5 on the surface of the lesion site 8 , so that there is a preset irradiation distance between the laser irradiator 3 and the lesion site 8 .

[0054] After the laser irradiator 3 and the lesion site 8 reach a preset irradiation distance, the lesion site 8 is irradiated with a therapeutic light beam having a first wavelength emitted by the irradiation light source.

[0055] After the irradiation treatment of the lesion site 8 is completed, the lesion site is shielded from light to allow the photosensitizer in the lesion site to metabolize.

[0056] The present invention uses specific embodiments to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for those skilled in the art, according to the idea of ​​the present invention, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as a limitation on the present invention.

Claims

1. A high-precision photodynamic therapy device, characterized in that: A laser irradiator is included, wherein the laser irradiator comprises: shell; an irradiation light source disposed in the housing, the irradiation light source being capable of generating a therapeutic light having a first wavelength to irradiate a surface to be irradiated; a plurality of ranging light sources, which are disposed in the housing, the plurality of ranging light sources can generate a plurality of ranging light rays having a second wavelength, and the plurality of ranging light rays can converge into a laser spot on the surface to be irradiated at a preset irradiation distance; and A plurality of positioning light sources are arranged in the housing, the plurality of positioning light sources can generate a plurality of positioning light rays having a third wavelength, the plurality of positioning light rays can generate a plurality of straight line projections on the surface to be irradiated, and the plurality of straight line projections at least intersect in pairs to form an irradiation area; Wherein, a plurality of the positioning light sources are arranged along the edge of the irradiation light source, so that the treatment light can be arranged within the irradiation area.

2. The high-precision photodynamic therapy device according to claim 1, characterized in that: The laser irradiator includes three ranging light sources, which can generate three ranging lights with the second wavelength. The three ranging lights can converge into a laser spot on the surface to be irradiated at the preset irradiation distance when the surface to be irradiated is parallel to the surface of the laser irradiator.

3. The high-precision photodynamic therapy device according to claim 1, characterized in that: The laser irradiator includes at least three positioning light sources.

4. The high-precision photodynamic therapy device according to claim 3, characterized in that: The laser irradiator comprises four positioning light sources, which are arranged around the edge of the irradiation light source and can form a rectangular irradiation area on the surface to be irradiated.

5. The high-precision photodynamic therapy device according to claim 1, characterized in that: The high-precision photodynamic therapy device also includes a chassis and an adjustment rod, and the laser irradiator is connected to the chassis via the adjustment rod.

6. The high-precision photodynamic therapy device according to claim 5, characterized in that: The chassis is provided with a controller to set the preset irradiation distance and irradiation time, and the laser irradiator is electrically connected to the controller.

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