A stirring device for biological reagent

Abstract

The present invention relates to the technical field of biological reagent production and processing, and discloses a stirring device for biological reagent, including a mixing box, a mixing mechanism, a powder feeding mechanism, a liquid outlet pipe, a stop valve and a liquid inlet pipe, wherein the mixing mechanism is arranged on the side of the top of the mixing box, the powder feeding mechanism is arranged in the middle of the top of the mixing box, the bottom of the liquid inlet pipe is fixedly connected with the side of the top of the mixing box, the mixing mechanism includes a first stirrer, a second stirrer, a belt and a rotating motor, and the first stirrer and the second stirrer both include a rotating rod, a rotating wheel and a stirring blade. The present invention drives the first stirrer to rotate by the rotating motor, and the second stirrer rotates together under the transmission of the belt, so as to uniformly and quickly stir the solution and powder inside the mixing box, thereby increasing the stirring efficiency, and the dispersed feeding method of the powder feeding mechanism is used to make the biological reagent mix faster and more uniformly in the preparation process.

Description

Technical Field

[0001] The invention relates to the technical field of biological reagent production and processing, in particular to a stirring device for biological reagents. Background Art

[0002] In the biopharmaceutical industry, during the production process, it is necessary to mix the drugs or reagents. Biological reagents are mostly made by mixing various raw liquids or raw powders. In order to facilitate mixing, it is often necessary to use equipment and tools to assist in mixing. These equipment and tools are mixing devices for biological reagents. However, the existing stirring devices for biological reagents are generally single-axis stirring methods, which have low stirring efficiency and are difficult to stir evenly because they are mixed with powders and solutions. Summary of the invention

[0003] The invention provides a stirring device for biological reagents, which stirs the biological reagents in a double-axis stirring manner and disperses and feeds powders, so that the biological reagents can be mixed faster and more evenly during the preparation process.

[0004] To achieve the above objectives, the present invention is implemented through the following technical solutions: a stirring device for biological reagents, including a mixing box, a mixing mechanism, a powder feeding mechanism, a liquid outlet pipe, a stop valve and a liquid inlet pipe, the mixing mechanism is arranged on the side of the top of the mixing box, the powder feeding mechanism is arranged in the middle of the top of the mixing box, the bottom of the liquid inlet pipe is fixedly connected to the side of the top of the mixing box, the liquid outlet pipe is fixedly connected to the middle of the bottom of the mixing box, and the stop valve is fixedly connected to the liquid outlet pipe.

[0005] The mixing mechanism includes a first agitator, a second agitator, a belt and a rotating motor, the first agitator and the second agitator both include a rotating rod, a rotating wheel and a stirring blade, the bottom of the rotating rod passes through the side of the top of the mixing box and is movably connected to the mixing box through a bearing, the rotating wheel is fixedly connected to the top of the outer surface of the rotating rod, the rotating wheel on the first agitator is transmission-connected to the rotating wheel on the second agitator through a belt, the top of the rotating rod is fixedly connected to the output shaft at the bottom of the rotating motor, and the stirring blade is fixedly connected to the outer surface of the rotating rod at one end of the inner cavity of the mixing box.

[0006] The powder feeding mechanism includes a feeding box, a sealing plate, a feeding pipe, a guide pipe, a diverter pipe, a semicircular filter and a loose powder net. The top of the feeding box is movably connected to one side of the sealing plate by a hinge. The feeding pipe is fixedly connected to the middle part of the bottom of the feeding box, and the middle part of the bottom of the feeding pipe is fixedly connected to the top of the guide pipe. The semicircular filter is fixedly connected to one end of the guide pipe located in the inner cavity of the feeding pipe. The shape of the semicircular filter is semicircular. The top of the diverter pipe is fixedly connected to the side of the bottom of the feeding pipe. The guide pipe and the diverter pipe both pass through the top of the mixing box and are fixedly connected to the mixing box. The guide pipe and the diverter pipe are fixedly connected to the loose powder net at one end located in the inner cavity of the mixing box.

[0007] Preferably, a fixing frame is fixedly connected to the outer surface of the rotating motor, and the bottom of the fixing frame is fixedly connected to the top of the mixing box.

[0008] Preferably, the model of the rotating motor is: YM.

[0009] Preferably, a handle is fixedly connected to the side surface of the top of the sealing plate, and a rubber sleeve is sleeved on the outer surface of the handle.

[0010] Preferably, the material guide pipe is composed of a vertical circular tube at the top and a truncated cone-shaped tube at the bottom, and the diverter pipe is composed of an inclined circular tube at the top and a truncated cone-shaped tube at the bottom.

[0011] Preferably, there are two diverter pipes, which are symmetrically distributed on both sides of the bottom of the feeding pipe.

[0012] By means of the above technical solution, the present invention provides a stirring device for biological reagents, which has at least the following beneficial effects:

[0013] (1) The stirring device for biological reagent drives the first stirrer to rotate through a rotating motor, and the second stirrer rotates together under the transmission of a belt, so as to evenly and quickly stir the solution and powder in the mixing box, thereby increasing the stirring efficiency. The dispersed feeding method of the powder feeding mechanism enables the biological reagent to be mixed faster and more evenly during the preparation process, thereby increasing the efficiency of the biological reagent preparation.

[0014] (2) The stirring device for biological reagents is characterized in that the raw material powder is placed inside a feeding box and discharged through a feeding pipe. When the powder contacts a semicircular filter screen, the powder is diverted under the obstruction of the semicircular filter screen so that the powder enters a feed pipe and a diversion pipe respectively, and the powder is dispersed and discharged through a powder dispersing net to prevent the powder from being concentrated at one point and contacting with a feeding solution to form lumps, thereby affecting the uniformity of mixing and increasing the mixing efficiency. The rotating motor causes the mixing box to vibrate to a certain extent, thereby vibrating the semicircular filter screen and the powder dispersing net to prevent the powder from being blocked. The sealing plate facilitates the sealing of the feeding box to prevent the powder from splashing. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The accompanying drawings described herein are used to provide a further understanding of the present invention and constitute a part of this application:

[0016] Figure 1 It is a structural schematic diagram of the present invention;

[0017] Figure 2 For the present invention Figure 1 Schematic diagram of the structure of the middle A part;

[0018] Figure 3 For the present invention Figure 1 Schematic diagram of the structure of part B.

[0019] In the figure: 1 mixing box, 2 mixing mechanism, 201 first agitator, 2011 rotating rod, 2012 rotating wheel, 2013 stirring blade, 202 second agitator, 203 belt, 204 rotating motor, 205 fixed frame, 3 powder feeding mechanism, 301 feeding box, 302 sealing plate, 303 handle, 304 feeding pipe, 305 material guide pipe, 306 diverter pipe, 307 semicircular filter screen, 308 loose powder screen, 4 liquid outlet pipe, 5 stop valve, 6 liquid inlet pipe. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0021] See also Figure 1-3 The present invention provides a technical solution: a stirring device for biological reagents, comprising a mixing box 1, a mixing mechanism 2, a powder feeding mechanism 3, a liquid outlet pipe 4, a stop valve 5 and a liquid inlet pipe 6, the mixing mechanism 2 is arranged on the side of the top of the mixing box 1, the powder feeding mechanism 3 is arranged in the middle of the top of the mixing box 1, the bottom of the liquid inlet pipe 6 is fixedly connected to the side of the top of the mixing box 1, the liquid outlet pipe 4 is fixedly connected to the middle of the bottom of the mixing box 1, and the stop valve 5 is fixedly connected to the liquid outlet pipe 4.

[0022] The mixing mechanism 2 includes a first agitator 201, a second agitator 202, a belt 203 and a rotating motor 204. The first agitator 201 and the second agitator 202 both include a rotating rod 2011, a rotating wheel 2012 and a stirring blade 2013. The bottom of the rotating rod 2011 passes through the side of the top of the mixing box 1 and is movably connected to the mixing box 1 through a bearing. The rotating wheel 2012 is fixedly connected to the top of the outer surface of the rotating rod 2011. The rotating wheel 2012 on the first agitator 201 is transmission-connected to the rotating wheel 2012 on the second agitator 202 through the belt 203. The top of the rotating rod 2011 is fixedly connected to the output shaft at the bottom of the rotating motor 204. The outer surface of the rotating motor 204 is fixedly connected with a fixing frame 205. The bottom of the fixing frame 205 is fixedly connected to the top of the mixing box 1. The model of the rotating motor 204 is: Y80M1. The stirring blade 2013 is fixedly connected to the outer surface of the rotating rod 2011 located at one end of the inner cavity of the mixing box 1.

[0023] The first agitator 201 is driven to rotate by the rotating motor 204, and the second agitator 202 is driven to rotate together with the belt 203, so that the solution and powder in the mixing box 1 are evenly and quickly stirred, thereby increasing the stirring efficiency. The dispersed feeding method of the powder feeding mechanism 3 is used to make the biological reagent mix faster and more evenly during the preparation process, thereby increasing the efficiency of the biological reagent preparation.

[0024] The powder feeding mechanism 3 includes a feeding box 301, a sealing plate 302, a feeding pipe 304, a guide pipe 305, a shunt pipe 306, a semicircular filter screen 307 and a loose powder screen 308. The top of the feeding box 301 is movably connected to one side of the sealing plate 302 through a hinge, and a pull handle 303 is fixedly connected to the side of the top of the sealing plate 302. The outer surface of the pull handle 303 is sleeved with a rubber sleeve. The feeding pipe 304 is fixedly connected to the middle part of the bottom of the feeding box 301, and the middle part of the bottom of the feeding pipe 304 is fixedly connected to the top of the guide pipe 305. The semicircular filter screen 307 is fixedly connected to one end of the guide pipe 305 located in the inner cavity of the feeding pipe 304. The shape is semicircular, the top of the diverter pipe 306 is fixedly connected to the side of the bottom of the feeding pipe 304, the guide pipe 305 is composed of a vertical circular tube at the top and a truncated cone-shaped tube at the bottom, the diverter pipe 306 is composed of an inclined circular tube at the top and a truncated cone-shaped tube at the bottom, there are two diverter pipes 306, and the two diverter pipes 306 are symmetrically distributed on both sides of the bottom of the feeding pipe 304, the guide pipe 305 and the diverter pipe 306 have no contact with the belt 203, the guide pipe 305 and the diverter pipe 306 both pass through the top of the mixing box 1 and are fixedly connected to the mixing box 1, and the end of the guide pipe 305 and the diverter pipe 306 located in the inner cavity of the mixing box 1 is fixedly connected with a loose powder net 308.

[0025] The raw material powder is placed inside the feeding box 301 and discharged through the feeding pipe 304. When the powder contacts the semicircular filter screen 307, the powder is diverted under the obstruction of the semicircular filter screen 307, so that the powder enters the guide pipe 305 and the diversion pipe 306 respectively, and the powder is broken up and discharged through the loose powder net 308 to prevent the powder from being concentrated at one point and contacting the feeding solution to form lumps, which affects the uniformity of mixing and increases the mixing efficiency. Under the rotation of the rotating motor 204, the mixing box 1 generates a certain vibration to vibrate the semicircular filter screen 307 and the loose powder net 308 to prevent powder blockage. The sealing plate 302 facilitates the sealing of the feeding box 301 to prevent powder splashing.

[0026] When in use, the raw material solution is first introduced into the interior of the mixing box 1 through the liquid inlet pipe 6, the rotating motor 204 is turned on to drive the first agitator 201 to rotate, and the second agitator 202 is rotated together under the transmission of the belt 203 to evenly and quickly stir the solution and powder in the mixing box 1, and the raw material powder is poured into the interior of the feeding box 301, and the raw material powder is discharged through the feeding pipe 304. When the powder contacts the semicircular filter screen 307, it is diverted under the obstruction of the semicircular filter screen 307, so that the powder enters the guide pipe 305 and the diversion pipe 306 respectively, and the powder is broken up and discharged through the loose powder net 308 to prevent the powder from being concentrated at one point and contacting the feeding solution to form agglomerations. Under the rotation of the rotating motor 204, the mixing box 1 generates a certain vibration to vibrate the semicircular filter screen 307 and the loose powder net 308 to prevent powder blockage.

[0027] After mixing for ten minutes, the rotating motor 204 is turned off to stop the first stirrer 201 and the second stirrer 202 from rotating, and the stop valve 5 is opened to discharge the mixed biological reagent through the liquid outlet pipe 4 .

[0028] The above is a detailed introduction to the stirring device for biological reagents provided by the present invention. The present invention uses specific examples to illustrate the principles and implementation methods of the present invention, and the description of the above embodiments is only used to help understand the method of the present invention and its core idea. It should be pointed out that for ordinary technicians in this technical field, without departing from the principle of the present invention, the present invention can also be improved and modified, and these improvements and modifications also fall within the scope of protection of the claims of the present invention.

Claims

1. A stirring device for biological reagents, comprising a mixing box (1), a mixing mechanism (2), a powder feeding mechanism (3), a liquid outlet pipe (4), a stop valve (5) and a liquid inlet pipe (6), characterized in that: The mixing mechanism (2) is arranged on the side of the top of the mixing box (1), the powder feeding mechanism (3) is arranged in the middle of the top of the mixing box (1), the bottom of the liquid inlet pipe (6) is fixedly connected to the side of the top of the mixing box (1), the liquid outlet pipe (4) is fixedly connected to the middle of the bottom of the mixing box (1), and the stop valve (5) is fixedly connected to the liquid outlet pipe (4); The mixing mechanism (2) comprises a first agitator (201), a second agitator (202), a belt (203) and a rotating motor (204); the first agitator (201) and the second agitator (202) both comprise a rotating rod (2011), a rotating wheel (2012) and a stirring blade (2013); the bottom of the rotating rod (2011) passes through the side surface of the top of the mixing box (1) and is movably connected to the mixing box (1) via a bearing; the rotating wheel (2012) is fixedly connected to the top of the outer surface of the rotating rod (2011); the rotating wheel (2012) on the first agitator (201) is transmission-connected to the rotating wheel (2012) on the second agitator (202) via the belt (203); the top of the rotating rod (2011) is fixedly connected to the output shaft at the bottom of the rotating motor (204); and the stirring blade (2013) is fixedly connected to the outer surface of the rotating rod (2011) located at one end of the inner cavity of the mixing box (1); The powder feeding mechanism (3) comprises a feeding box (301), a sealing plate (302), a feeding pipe (304), a material guide pipe (305), a diversion pipe (306), a semicircular filter screen (307) and a loose powder screen (308); the top of the feeding box (301) is movably connected to one side of the sealing plate (302) via a hinge; the feeding pipe (304) is fixedly connected to the middle of the bottom of the feeding box (301); the middle of the bottom of the feeding pipe (304) is fixedly connected to the top of the material guide pipe (305); the semicircular filter screen (307) is connected to the bottom of the feeding box (301); The filter screen (307) is fixedly connected to one end of the material guide pipe (305) located in the inner cavity of the feeding pipe (304); the shape of the semicircular filter screen (307) is semicircular; the top of the diverter pipe (306) is fixedly connected to the side of the bottom of the feeding pipe (304); the material guide pipe (305) and the diverter pipe (306) both pass through the top of the mixing box (1) and are fixedly connected to the mixing box (1); and the ends of the material guide pipe (305) and the diverter pipe (306) located in the inner cavity of the mixing box (1) are fixedly connected to a loose powder screen (308).

2. A stirring device for biological reagent according to claim 1, characterized in that: A fixing frame (205) is fixedly connected to the outer surface of the rotating motor (204), and the bottom of the fixing frame (205) is fixedly connected to the top of the mixing box (1).

3. A stirring device for biological reagent according to claim 1, characterized in that: The model of the rotating motor (204) is: Y80M1.

4. A stirring device for biological reagent according to claim 1, characterized in that: A pull handle (303) is fixedly connected to the side surface of the top of the sealing plate (302), and a rubber sleeve is sleeved on the outer surface of the pull handle (303).

5. A stirring device for biological reagent according to claim 1, characterized in that: The material guide pipe (305) is composed of a vertical circular pipe at the top and a truncated cone-shaped pipe at the bottom, and the flow distribution pipe (306) is composed of an inclined circular pipe at the top and a truncated cone-shaped pipe at the bottom.

6. A stirring device for biological reagent according to claim 1, characterized in that: There are two diversion tubes (306), and the two diversion tubes (306) are symmetrically distributed on both sides of the bottom of the feeding tube (304).

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