A method for determining vaccine safety using microelectronic tags

Abstract

The present invention is a method for determining vaccine safety using a microelectronic tag. The code on the microelectronic tag includes a tag classification identification code and a GTIN code. The microelectronic tag is edited and written before the cold chain process. The cold chain process information is automatically recorded and stored by the microelectronic tag during the cold chain storage and transportation process, and is actively or passively uploaded to a database. The tag code is bound to the vaccine manufacturer information, vaccine information, cold chain rules and cold chain process information set in the database, and a corresponding relationship is formed. The method for determining vaccine safety includes the following steps: reading the code; determining whether the tag and the vaccine are bound effectively; determining whether the vaccine is within the validity period; determining whether the cold chain process of the vaccine is safe according to the cold chain rules, and determining that it is safe if it complies with the cold chain rules, and that it is unsafe if it does not comply with the cold chain rules. Considering all aspects of the vaccine cold chain process, it has high reliability and reasonable process settings. It is highly targeted for the strictly controlled mode of vaccines, and can also be used in similar fields, with good promotion value.

Description

Technical Field

[0001] The present invention relates to a method for determining the safety of a vaccine, and in particular to a method for determining the safety of a vaccine in a cold chain process using a microelectronic tag. Background Art

[0002] Vaccines are a special type of biochemical reagent. In each link of actual production, transportation, and use, they must strictly comply with storage temperature requirements, otherwise they may lose their activity and may also produce unforeseen side effects. In particular, the cold chain transportation and storage of vaccines from producers to users is a very important link. In many vaccine incidents, problems arise in the transportation and storage links.

[0003] In the past, the monitoring of the vaccine cold chain process mainly relied on manual temperature records, which were prone to negligence and difficult to trace the entire process. This management model could hardly ensure the safety of vaccines. Later, an irreversible thermosensitive label or color-changing label appeared. Once overtemperature occurred, it would irreversibly change color. However, such labels have certain drawbacks, that is, they cannot track the real-time temperature of the vaccine cold chain process, cannot reflect the overtemperature range of the cold chain process, are insensitive to low temperatures, and may show as invalid for short-term exposure that will not cause harm, resulting in great waste and failing to truly reflect the various environmental changes in the vaccine cold chain process.

[0004] Now, microelectronic labels can fully record the entire process of vaccine storage and transportation. They can convert temperature and time information into codes with very small data amounts and store the records in the labels. Data can be easily read and analyzed, which can scientifically monitor the traceability of the vaccine's cold chain process, which is very efficient and scientific.

[0005] However, this research and judgment process still has certain risks and difficulties. The scientific nature of the research and judgment process is the last mile of vaccine safety. Moreover, such research and judgment needs to ensure consistency and seriousness. It cannot rely entirely on manual work, and various safety factors must be considered. Therefore, a scientific research and judgment method is very necessary. Summary of the invention

[0006] The present invention provides a method for determining vaccine safety using microelectronic tags. The purpose is to provide a method for determining vaccine safety based on the technology of using microelectronic tags. Such a method is suitable for automatic determination and is scientific and reasonable.

[0007] The technical solution of the present invention is: a method for determining vaccine safety using a microelectronic tag, wherein the microelectronic tag is used in the cold chain process of the vaccine, the microelectronic tag has a code, the code at least includes a tag classification identification code and a GTIN code, the cold chain process information is stored in the microelectronic tag, the cold chain process information includes vaccine temperature and time, the tag classification identification code and the GTIN code are edited and written into the microelectronic tag before the cold chain process, the tag classification identification code corresponds to the tag type in the database one-to-one, the GTIN code is at least bound to the cold chain rule code, the cold chain rule code corresponds to the cold chain rule in the database one-to-one, the cold chain process information is automatically recorded and stored by the microelectronic tag during the cold chain storage and transportation process, and is passively or actively uploaded to the database, the code is bound to the vaccine manufacturer information, vaccine information and cold chain process information set according to the rules in the database, and a one-to-one correspondence is formed, and the method for determining vaccine safety includes the following steps:

[0008] (1) The card reader terminal scans the code on the microelectronic tag;

[0009] (2) First, determine whether the binding of the tag and the vaccine is valid, that is, determine whether the code in the tag conforms to the coding rules set in the database, and whether it is consistent with the vaccine manufacturer information and vaccine information bound to the code entered and activated in the database. If so, proceed to step (3); if not, it is determined to be unsafe and an alarm is issued;

[0010] (3) Then determine whether the vaccine is within the validity period, calculate whether the difference between the scanning time and the production time recorded in the database is within the validity period of the vaccine, if so, proceed to step (4), if not, determine it is unsafe, and issue an alarm;

[0011] (4) Finally, determine whether the cold chain process of the vaccine is safe based on the cold chain rules. Read the cold chain rule code and call the corresponding cold chain rule in the database. Compare it with the cold chain process information, execute the algorithm according to the cold chain rules, and obtain the calculation results. If it complies with the cold chain rules, it is judged to be safe, and if it does not comply with the cold chain rules, it is judged to be unsafe. The logical judgment process ends.

[0012] Furthermore, the vaccine temperature and time included in the cold chain process information are recorded by collecting the vaccine temperature at fixed intervals.

[0013] Furthermore, the vaccine temperature is a temperature point, and the temperature point is recorded in the cold chain process information.

[0014] Furthermore, the vaccine temperature is a temperature range code, the temperature range code is recorded in the cold chain process information, and the temperature range code is corresponded one-to-one with the temperature range set in the database, and the temperature range includes at least a vaccine safe temperature range, a temperature range that can be briefly exposed, and an unsafe temperature range.

[0015] Furthermore, if it is determined to be unsafe in step (2) and an alarm is output, the vaccine cannot be used and the subsequent steps will not be judged.

[0016] Furthermore, when step (3) is judged to be unsafe and an alarm is output, the vaccine cannot be used and subsequent steps are no longer judged.

[0017] Furthermore, when step (4) is judged to be unsafe, the output is divided into two categories: risk and alarm. The risk means that the vaccine has certain safety risks, but it can still be used after review by the manufacturer, and the alarm means that the vaccine cannot be used.

[0018] Furthermore, the alarm means that the exposure time to excessive temperature exceeds the safe time allowed by the vaccine.

[0019] Furthermore, the risk refers to the fact that the time of exposure to over-temperature does not exceed the safe time, but the over-temperature situation exists.

[0020] Furthermore, the code also includes the UID card number as the vaccine dynamic information code and extended function code to achieve other information binding in the vaccine cold chain process.

[0021] Furthermore, the cold chain process information also includes location information, which records the location of the vaccine and enables more monitoring of the vaccine.

[0022] The beneficial effects of the present invention are

[0023] 1. Combined with the use of microelectronic tags, the label code is pre-written in the microelectronic tag according to the rules, and various code information is bound according to the rules. After the vaccine manufacturer completes production, the label code is activated and uploaded to the cloud database. Before the vaccine is administered, the label code can be read and compared with the cloud database coding information to check whether the label is valid and the authenticity of the vaccine, and it can calculate whether the vaccine is within the validity period, and the judgment logic is given.

[0024] 2. Combined with the cold chain temperature and duration information automatically recorded by the microelectronic tag during the cold chain process, the cold chain rules are automatically retrieved according to the cold chain rule code and compared to determine whether the vaccine is safe. The safety is divided into short-term exposure risks, which can prompt users to verify use or strengthen tracking. If the exposure time is exceeded, it can be judged as an alarm and cannot be used.

[0025] 3. This determination method takes into account all aspects of the cold chain process and has high reliability and reasonable process settings. It is highly targeted at the strictly controlled model of vaccines and can also be used in similar fields, and is worth promoting. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 It is a logic flow chart of the present invention. DETAILED DESCRIPTION

[0027] Example 1

[0028] A method for determining vaccine safety using a microelectronic tag, wherein the microelectronic tag is used in a cold chain process of the vaccine, wherein the microelectronic tag has a code, wherein the code at least includes a tag classification identification code and a GTIN code, wherein cold chain process information is stored in the microelectronic tag, wherein the cold chain process information includes vaccine temperature and time, wherein the tag classification identification code and the GTIN code are edited and written into the microelectronic tag before the cold chain process, wherein the tag classification identification code corresponds to a tag type in a database one-to-one, wherein the GTIN code is bound to at least a cold chain rule code, wherein the cold chain rule code corresponds to a cold chain rule in a database one-to-one, wherein the cold chain process information is automatically recorded and stored by the microelectronic tag during cold chain storage and transportation, and uploaded to a database passively or actively, wherein the code is bound to vaccine manufacturer information, vaccine information, and cold chain process information set in the database according to the rules, and forms a one-to-one correspondence, wherein the method for determining vaccine safety comprises the following steps:

[0029] (1) The card reader terminal scans the code on the microelectronic tag;

[0030] (2) First, determine whether the binding of the tag and the vaccine is valid, that is, determine whether the code in the tag conforms to the coding rules set in the database. If it is inconsistent with the vaccine manufacturer information and vaccine information bound to the code entered and activated in the database, it is judged as unsafe and an alarm is issued, and the vaccine cannot be used.

[0031] Example 2

[0032] A method for determining vaccine safety using a microelectronic tag, wherein the microelectronic tag is used in the cold chain process of the vaccine, the microelectronic tag has a code, the code at least includes a tag classification identification code and a GTIN code, the microelectronic tag stores cold chain process information, the cold chain process information includes vaccine temperature and time, the tag classification identification code and the GTIN code are edited and written into the microelectronic tag before cold chain storage and transportation, the tag classification identification code corresponds to the tag type in a database one-to-one, the GTIN code is at least bound to a cold chain rule code, the cold chain rule code corresponds to the cold chain rule in the database one-to-one, the cold chain process information is automatically recorded and stored by the microelectronic tag during the cold chain storage and transportation process, and is passively or actively uploaded to the database, the code is bound to the vaccine manufacturer information, vaccine information and cold chain process information set according to the rules in the database, and a one-to-one correspondence is formed, and the method for determining vaccine safety comprises the following steps:

[0033] (1) The card reader terminal scans the code on the microelectronic tag;

[0034] (2) First determine whether the binding of the label and the vaccine is valid, that is, determine whether the code in the label conforms to the coding rules set in the database. If it is consistent with the vaccine manufacturer information and vaccine information bound to the code entered and activated in the database, proceed to step (3);

[0035] (3) Then determine whether the vaccine is within the validity period. If the difference between the scan time and the production time recorded in the database is not within the validity period of the vaccine, it is judged as unsafe and an alarm is issued, and the vaccine cannot be used.

[0036] Example 3

[0037] A method for determining vaccine safety using a microelectronic tag, wherein the microelectronic tag is used in a cold chain process of the vaccine, wherein the microelectronic tag has a code, wherein the code at least includes a tag classification identification code and a GTIN code, wherein cold chain process information is stored in the microelectronic tag, wherein the cold chain process information includes vaccine temperature and time, wherein the tag classification identification code and the GTIN code are edited and written into the microelectronic tag before the cold chain process, wherein the tag classification identification code corresponds to a tag type in a database one-to-one, wherein the GTIN code at least includes a cold chain rule code, wherein the cold chain rule code corresponds to a cold chain rule in a database one-to-one, wherein the cold chain process information is automatically recorded and stored by the microelectronic tag during the cold chain process, and uploaded to the database passively or actively, wherein the code is bound to vaccine manufacturer information, vaccine information, and cold chain process information set in the database according to the rule, and forms a one-to-one correspondence, wherein the method for determining vaccine safety comprises the following steps:

[0038] (1) The card reader terminal scans the code on the microelectronic tag;

[0039] (2) First determine whether the binding of the label and the vaccine is valid, that is, determine whether the code in the label complies with the coding rules set in the database and is consistent with the vaccine manufacturer information and vaccine information bound to the code entered and activated in the database, and then proceed to step (3);

[0040] (3) Then determine whether the vaccine is within the validity period. If the difference between the scanning time and the production time recorded in the database is within the validity period of the vaccine, proceed to step (4);

[0041] (4) Finally, determine whether the cold chain process of the vaccine is safe based on the cold chain rules. Read the cold chain rule code and call the corresponding cold chain rule in the database, compare it with the cold chain process information, execute the algorithm according to the cold chain rules, and obtain the calculation results. If it meets the cold chain rules, it is determined to be safe and the vaccine can be used, and the logical judgment process ends.

[0042] Example 5

[0043] A method for determining vaccine safety using a microelectronic tag, wherein the microelectronic tag is used in a cold chain process of the vaccine, wherein the microelectronic tag has a code, wherein the code is at least bound to a tag classification identification code and a GTIN code, wherein cold chain process information is stored in the microelectronic tag, wherein the cold chain process information includes vaccine temperature and time, wherein the tag classification identification code and the GTIN code are edited and written into the microelectronic tag before the cold chain process, wherein the tag classification identification code corresponds to a tag type in a database one-to-one, wherein the GTIN code contains at least a cold chain rule code, wherein the cold chain rule code corresponds to a cold chain rule in a database one-to-one, wherein the cold chain process information is automatically recorded and stored by the microelectronic tag during cold chain storage and transportation, and uploaded to a database passively or actively, wherein the code is bound to vaccine manufacturer information, vaccine information, and cold chain process information set in the database according to the coding rule, and forms a one-to-one correspondence, wherein the method for determining vaccine safety comprises the following steps:

[0044] (1) The card reader terminal scans the code on the microelectronic tag;

[0045] (2) First determine whether the binding of the label and the vaccine is valid, that is, determine whether the code in the label complies with the coding rules set in the database and is consistent with the vaccine manufacturer information and vaccine information bound to the code entered and activated in the database, and then proceed to step (3);

[0046] (3) Then determine whether the vaccine is within the validity period. If the difference between the scanning time and the production time recorded in the database is within the validity period of the vaccine, proceed to step (4);

[0047] (4) Finally, determine whether the cold chain process of the vaccine is safe based on the cold chain rules. Read the cold chain rule code and call the corresponding cold chain rule in the database, compare it with the cold chain process information, execute the algorithm according to the cold chain rules, and obtain the calculation results. If it does not comply with the cold chain rules, it will be determined to be unsafe, and the logical judgment process ends.

[0048] Example 6

[0049] The difference from Example 5 is that after being determined to be unsafe, further analysis is performed. When it is determined to be unsafe in step (5), the output is divided into two categories: risk and alarm. The risk means that the vaccine has certain safety risks, but it may still be used after review by the manufacturer. The alarm means that the vaccine cannot be used.

[0050] In the corresponding cold chain information, the alarm means that the exposed over-temperature and time exceed the set safety limits.

[0051] In the corresponding cold chain information, the risk refers to the fact that the over-temperature and time of exposure do not exceed the set safety limits, but over-temperature conditions exist.

[0052] Example 7

[0053] The difference from Example 5 or 6 is that the vaccine temperature and time included in the cold chain process information are recorded by collecting the vaccine temperature at fixed intervals. The vaccine temperature is a temperature range code, which is recorded in the cold chain process information, and the temperature range code is matched one-to-one with the temperature range set in the database. The temperature range includes at least a vaccine safe temperature range, a temperature range that can be exposed for a short time, and an unsafe temperature range. This recording method has very little data volume and can save data space.

[0054] For example, in the cold chain rules, a 4-segment temperature rule is specified, code 00 represents 0~2 degrees Celsius, code 01 represents 2~8 degrees Celsius, code 10 represents 8~37 degrees Celsius, and code 11 represents greater than 37 degrees Celsius. Among them, code 01 is a safe temperature range, code 00 and 10 are temperature ranges that can be exposed for a short time, and code 11 is an unsafe temperature range. When recording, just record the binary code, and the interval of its collection time is set and fixed. When judging, read the cold chain rules saved in the background. For example, if the duration of code 00 is less than 24 hours, it can be output as a risk and the vaccine can still be used. If the duration of code 00 is greater than 24 hours, it must be output as an alarm and the vaccine cannot be used. Such judgment rules are verified by experiments and strictly stipulated, so they are serious. The recording and judgment principles of other temperature ranges are the same as the above content, and the setting of such temperature ranges meets the actual application requirements.

[0055] Of course, for some special areas, such as long-term storage and constant temperature warehouses, the temperature fluctuation is very small, or other situations that require strict recording of each temperature point, the recording space of the microelectronic tag can be increased, and the temperature value at fixed intervals can be recorded in real time, combined with the set interval time. The judgment method is consistent with the above technical method and can still be used.

[0056] In some cases, the UID card number can also be included in the code to expand the scope of monitoring. The cold chain process information also includes location information to monitor the location information of the vaccine.

[0057] This embodiment is an explanation of the best solution of the invention, and its protection scope shall be based on the description of the claims. Equivalent changes to the embodiment still fall within the protection scope of the present invention.

Claims

1. A method for determining vaccine safety using a microelectronic tag, characterized in that: A microelectronic tag is used in the cold chain process of the vaccine. The microelectronic tag has a code, which includes at least a tag classification identification code and a GTIN code. The cold chain process information is stored in the microelectronic tag, and the cold chain process information includes the vaccine temperature and time. The tag classification identification code and the GTIN code are edited and written into the microelectronic tag before the cold chain process. The tag classification identification code corresponds to the tag type in the database one-to-one. The GTIN code is at least bound to the cold chain rule code, and the cold chain rule code corresponds to the cold chain rule in the database one-to-one. The cold chain process information is automatically recorded and stored by the microelectronic tag during cold chain transportation and storage, and uploaded to the database passively or actively. The code is bound to the vaccine manufacturer information, vaccine information and cold chain process information set in the database according to the coding rules, and a one-to-one correspondence is formed. The method for determining vaccine safety includes the following steps: (1) The card reader terminal scans the code on the microelectronic tag; (2) First, determine whether the binding of the tag and the vaccine is valid, that is, determine whether the code in the tag conforms to the coding rules set in the database, and whether it is consistent with the vaccine manufacturer information and vaccine information bound to the code entered and activated in the database. If so, proceed to step (3); if not, it is determined to be unsafe and an alarm is issued; (3) Then determine whether the vaccine is within the validity period, calculate whether the difference between the scanning time and the production time recorded in the database is within the validity period of the vaccine, if so, proceed to step (4), if not, determine it is unsafe, and issue an alarm; (4) Finally, determine whether the cold chain process of the vaccine is safe based on the cold chain rules. Read the cold chain rule code and call the corresponding cold chain rule in the database. Compare it with the cold chain process information, execute the algorithm according to the cold chain rules, and obtain the calculation results. If it complies with the cold chain rules, it is judged to be safe, and if it does not comply with the cold chain rules, it is judged to be unsafe. The logical judgment process ends.

2. The method for determining vaccine safety using microelectronic tags according to claim 1, characterized in that: The vaccine temperature and time included in the cold chain process information are recorded by collecting the vaccine temperature at fixed intervals.

3. The method for determining vaccine safety using microelectronic tags according to claim 2, characterized in that: The vaccine temperature is a temperature point, and the temperature point is recorded in the cold chain process information.

4. The method for determining vaccine safety using microelectronic tags according to claim 2, characterized in that: The vaccine temperature is a temperature range code. The temperature range code is recorded in the cold chain process information, and the temperature range code is matched one-to-one with the temperature range set in the database. The temperature range includes at least a vaccine safe temperature range, a temperature range that can be exposed for a short time, and an unsafe temperature range.

5. The method for determining vaccine safety using microelectronic tags according to claim 1, characterized in that: If it is determined to be unsafe in step (2) and an alarm is output, the vaccine cannot be used and the subsequent steps will not be judged.

6. The method for determining vaccine safety using microelectronic tags according to claim 1, characterized in that: If step (3) is judged as unsafe and an alarm is output, the vaccine cannot be used and subsequent steps will not be judged.

7. The method for determining vaccine safety using microelectronic tags according to claim 1, characterized in that: When step (4) is judged as unsafe, the output is divided into two categories: risk and alarm. The risk means that the vaccine has certain safety risks, but it may still be used after review by the manufacturer. The alarm means that the vaccine cannot be used.

8. The method for determining vaccine safety using microelectronic tags according to claim 7, characterized in that: The alarm means that the exposure time to excessive temperature exceeds the safe time allowed by the vaccine.

9. The method for determining vaccine safety using microelectronic tags according to claim 7 or 8, characterized in that: The risk refers to the fact that the exposure time to over-temperature does not exceed the safe time, but the over-temperature situation exists.

10. The method for determining vaccine safety using a microelectronic tag according to claim 1, characterized in that: The code also includes a UID card number, and the cold chain process information also includes location information.

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