Nasopharyngeal swab self-service collection kit

Abstract

The present invention belongs to the field of biomedicine technology, and specifically relates to a nasopharyngeal swab self-service collection kit, including a nasopharyngeal swab and a guide structure, wherein the guide structure includes a guide substructure, and the guide substructure includes a C-shaped tubular guide portion, one end of the guide portion opens at the entrance of the inferior nasal meatus, and the other end of the guide portion opens at the nostril on the same side of the inferior nasal meatus. This kit can enable patients to collect nasopharyngeal swabs by themselves, assist patients to correctly insert nasopharyngeal swabs into the nasopharynx, improve the success rate of self-service sampling, and solve the technical problems of high exposure risks of medical staff directly collecting samples and high difficulty of self-service collection operations for patients. This solution can be applied to medical practice operations such as sampling and detection of highly contagious respiratory infectious diseases such as new coronary pneumonia.

Description

Technical Field

[0001] The invention belongs to the technical field of biomedicine, and in particular relates to a nasopharyngeal swab self-service collection kit. Background Art

[0002] In the medical practice of new coronavirus nucleic acid detection, oropharyngeal swabs and nasopharyngeal swabs are often used for sampling. Among them, the accuracy of nasopharyngeal swabs is higher than that of oropharyngeal swabs, so in the actual adoption process, nasopharyngeal swabs are more widely used. The existing nasopharyngeal swabs include a rod and a head (nasopharyngeal swabs are slender cotton swabs). The sampling process using nasopharyngeal swabs is as follows: clean the front end of the nostrils and nasal vestibule to prevent secretions from affecting the sampling process; then put the head of the nasopharyngeal swab into normal saline to moisten it, and then insert the nasopharyngeal swab into the nostrils in a direction perpendicular to the human face until the head of the nasopharyngeal swab reaches the nasopharynx, so that the swab stays in the nose for 15-30 seconds, and then gently rotate the nasopharyngeal swab; finally, put the nasopharyngeal swab into a test tube containing virus transport medium (virus culture fluid), break the rod of the nasopharyngeal swab that exceeds the length of the test tube, cover the test tube cap, and transport the test tube containing the nasopharyngeal swab to the designated nucleic acid testing laboratory for testing. The existing nasopharyngeal swab collection process is all operated by medical staff, but the new coronavirus is highly contagious, and the collection of samples by nasopharyngeal swabs poses a serious risk of exposure to medical staff. If patients (suspected patients) can collect samples by themselves, the risk of sampling by medical staff can be greatly reduced. However, it is relatively difficult to collect samples using nasopharyngeal swabs, and the existing nasopharyngeal swab collection methods and devices bring significant discomfort to patients. It is difficult for people who have not received professional training to insert the swab head of the nasopharyngeal swab into the nasopharynx, or the nasopharyngeal swab does not stay in the nasopharynx for enough time, and the amount of secretions collected is insufficient, which ultimately leads to sample collection failure and subsequent nucleic acid tests with false negatives (or a high false negative ratio). It is urgent to develop a nasopharyngeal swab kit that can assist patients in collecting samples by themselves and has good comfort to meet the detection needs of highly contagious diseases such as new coronary pneumonia. Summary of the invention

[0003] The purpose of the present invention is to provide a nasopharyngeal swab self-service collection kit, which can enable patients to complete nasopharyngeal swab sampling by themselves with relatively reduced painful experience, assist patients to correctly insert the nasopharyngeal swab into the nasopharynx, improve the success rate of self-service sampling, and solve the technical problems of high exposure risks when medical staff directly collect samples and high difficulty of self-service collection operation for patients.

[0004] To solve the above technical problems, the technical solution of the present invention is as follows:

[0005] A nasopharyngeal swab self-service collection kit includes a nasopharyngeal swab and a guide structure, wherein the guide structure includes a guide substructure, and the guide substructure includes a bent tubular guide portion, and the guide portion is used to guide the nasopharyngeal swab into the inferior nasal passage.

[0006] Using the above technical scheme, the technical principle and beneficial effects are as follows: This scheme sets up a guide structure for the nasopharyngeal swab, one end of the guide part opens at the entrance of the inferior nasal meatus, and the other end opens at the nostril on the same side of the inferior nasal meatus, which can help people who have no experience in nasopharyngeal sampling to find the correct entrance of the inferior nasal meatus. One end of the guide part opens at the entrance of the inferior nasal meatus, and the other end of the guide part opens at the nostril on the same side of the inferior nasal meatus. When in use, after inserting the guide structure into the nostril, use the nasopharyngeal swab for sampling, and insert the swab head into the C-shaped tubular guide part. Through the guiding effect of the guide structure, the swab head can be smoothly inserted into the inferior nasal meatus. Through the setting of the guide structure, it can help patients (suspected patients) to achieve self-service sampling in a simple, convenient and easy way, and medical staff are no longer required to conduct one-on-one sampling, thereby reducing the exposure risk of medical staff.

[0007] Patients without sampling experience (suspected patients) usually find it difficult to find the opening of the inferior nasal meatus toward the nasal vestibule (the entrance of the inferior nasal meatus), and it is easy to insert the nasopharyngeal swab in a direction parallel to the face. Such a sampling site is wrong and sampling of the nasopharynx cannot be achieved. In addition, there are many nasal hairs distributed near the nostrils and on the inner wall of the nasal vestibule, and more secretions containing pollutants (dust, bacteria, viruses, etc.) are adsorbed on the nasal hairs. If the swab head is contaminated with secretions containing pollutants, it may affect the sampling and detection results and reduce the accuracy of the detection. And after the swab head is contaminated with secretions containing pollutants, and then goes deep into the nasopharynx, the swab head may bring pathogenic substances such as bacteria and viruses to the nasopharynx, which may cause infection. In addition to the above problems, there are many sensory nerve endings distributed near the nostrils and on the inner wall of the nasal vestibule. The swab head may irritate the nasal cavity of the patient (suspected patient), causing sneezing, increased nasal secretions and other reactions, affecting the smooth progress of sampling. If the patient (suspected patient) has symptoms of upper respiratory tract infection and swollen nasal cavity, it will further increase the difficulty of inserting the nasopharyngeal swab into the inferior nasal meatus. The guiding structure of this scheme can assist the patient (suspected patient) to find the opening of the inferior nasal meatus toward the nasal vestibule, prevent the pollutants near the nostrils and on the inner wall of the nasal vestibule from contaminating the swab head, and prevent the swab head from irritating the nasal cavity (especially the nasal cavity at the nasal vestibule), which can solve the above problems.

[0008] In summary, the beneficial effects of the self-service collection kit of this solution are:

[0009] 1. This kit helps patients (suspected patients) find the entrance to the inferior nasal meatus, prevents pollutants near the nostrils and on the inner wall of the nasal vestibule from contaminating the swab head, and solves the problem that it is difficult for people without professional training to insert the swab head of the nasopharyngeal swab into the nasopharynx.

[0010] 2. This kit can prevent the swab head from irritating the nasal cavity (especially the nasal cavity near the nasal vestibule), increase the comfort level of patients (suspected patients), solve the problems of insufficient residence time of nasopharyngeal swabs in the nasopharynx and insufficient secretion collection, and solve the problem of false negatives (or a high false negative ratio) in nucleic acid tests due to failed sample collection.

[0011] 3. This kit can assist patients (suspected patients) in self-collection, which can greatly reduce the sampling risk for medical staff.

[0012] 4. Patients (suspected patients) can use nasopharyngeal swabs to collect nucleic acid test samples by themselves, which can realize parallel collection by multiple people without waiting for medical staff (the number of medical staff is limited during the outbreak) to collect samples in turn. This greatly reduces the sample collection time and improves work efficiency, especially for situations where large-scale population screening needs to be completed in a short period of time.

[0013] 5. Since the present invention can assist in parallel sampling of patients, the sample collection time is reduced, the stay time (queue waiting time) of suspected patients (who may not be infected) in the hospital is reduced, and the exposure risk of suspected patients is also reduced, avoiding them from being infected while waiting in the hospital. In addition, since the kit of the present invention has complete self-service operability, with the support of an intelligent platform or storage device, the operator can complete the kit acquisition on storage devices such as communities and hospitals (such as biosafety cabinets with self-service sales or access functions), self-sample at home, and then promptly send the sample to the testing agency or return it to the above-mentioned biosafety cabinet, further reducing the exposure risk of patients or medical staff.

[0014] Furthermore, the guide substructure also includes a limiting portion, which is located at an end of the guide portion away from the entrance of the inferior nasal cavity.

[0015] By adopting the above technical solution, the limiting part prevents the user from inserting the guide part too deeply, and also facilitates the removal of the guide structure after use.

[0016] Furthermore, the number of the guide substructures is two.

[0017] Using the above technical solution, nasopharyngeal swab sampling is usually performed from both nostrils to ensure the accuracy of sampling, so two guide substructures need to be set up.

[0018] Furthermore, the guide structure is made of silicone.

[0019] By adopting the above technical solution, the silicone material is soft, which can prevent the guide structure from poking the nasal cavity.

[0020] Furthermore, the nasopharyngeal swab includes a swab head, and an indicator light is provided on the top of the swab head.

[0021] Using the above technical solution, the indicator light can help confirm whether the swab head has entered the nasopharynx. When the patient (suspected patient) needs to take a sample of nasopharyngeal secretions, insert the swab head from the nostril (the swab head has been soaked with saline at this time), maintain the nasopharyngeal swab perpendicular to the patient's (suspected patient's) face, and insert the swab head into the inferior nasal meatus through the nasal vestibule until the swab head enters the nasopharynx. For patients (suspected patients) who have no operating experience, it is usually difficult to tell whether the swab head has been inserted into the nasopharynx. At this time, the patient (suspected patient) can open his mouth and face the mirror or mobile phone to observe whether there is a light signal from the indicator light in the pharynx. If the light signal of the indicator light can be observed, it means that the swab head has entered the nasopharynx and the sampling site is correct.

[0022] Furthermore, the indicator light outer cover has a spherical cover.

[0023] By adopting the above technical solution, the spherical cover facilitates the swab head to pass through the nasal cavity and prevents the top of the swab head from poking the inner wall of the nasal cavity.

[0024] Furthermore, a brush-shaped sampler is provided in the swab head, and the brush-shaped sampler is slidably connected to the inner wall of the swab head.

[0025] By adopting the above technical solution, the brush sampler slides in the swab head so that the brush sampler can be extended from the swab head to the nasopharynx. The swab head is provided with a brush sampler. When the nasopharyngeal swab is extended into the nasopharynx, the brush sampler will not contact the nasal cavity, thus avoiding contamination of the brush sampler and reducing the stimulation to the nasal passage mucosa during the process, thereby reducing the painful experience of sampling and improving the sampling quality.

[0026] Furthermore, a driving structure and a power structure are also provided in the nasopharyngeal swab; one end of the brush-shaped sampler is fixed on the driving structure, the power structure includes a trachea and an airbag, and the driving structure includes a piston; the piston is slidably and sealingly connected to the inner wall of the trachea.

[0027] By adopting the above technical solution, the power structure enables the pushing structure to move in the trachea, thereby pushing the brush-shaped sampler from the swab head to the nasopharynx.

[0028] Furthermore, the nasopharyngeal swab also includes a connecting rod and a swab handle, wherein the connecting rod is used to connect the swab head and the swab handle; the diameter of the swab handle is larger than the diameter of the connecting rod, and a power source is provided in the swab handle.

[0029] With the above technical solution, the connecting rod is used to support and push the swab head into the nasopharynx; the diameter of the swab handle is relatively large to form a space for accommodating a power source. If the sum of the lengths of the connecting rod and the swab head is set to match the depth of the nasopharynx, since the diameter of the swab handle is larger than the diameter of the connecting rod, when the upper surface of the swab handle is close to the nose wing or the limiting part of the guide structure, it can prevent the nasopharyngeal swab from continuing to penetrate the nasal cavity, thereby prompting the user that the insertion depth of the nasopharyngeal swab is appropriate, thereby avoiding the situation where an inexperienced user mistakenly inserts the nasopharyngeal swab too deeply and causes damage to the nasal cavity or pharynx. The swab handle set according to this solution has the dual functions of being convenient for the user to hold and prompting the user of the insertion depth of the swab head.

[0030] Furthermore, the swab head comprises a swab head part I and a swab head part II, and an obtuse angle is formed between the swab head part I and the swab head part II.

[0031] With the above technical solution, since the soft palate has an arc, the swab head is bent to better fit the arc of the soft palate. Compared with a straight swab head, this solution can insert the swab head deeper into the nasopharynx, and the sampling is more accurate. In addition, the indicator light of the curved swab head of this solution can point to the epiglottis of the patient (suspected patient), and when the mouth is opened, the light signal of the indicator light can be more easily observed. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 This is a midsagittal section of the nasal cavity.

[0033] Figure 2 A front view of a nasopharyngeal swab according to prior art.

[0034] Figure 3 It is a front view of the guide structure of embodiment 1 of the present invention.

[0035] Figure 4 It is a right view of the guide structure of embodiment 1 of the present invention.

[0036] Figure 5 A front view of the nasopharyngeal swab of Example 2 of the present invention.

[0037] Figure 6 for Figure 5 A longitudinal cross-sectional view of section A.

[0038] Figure 7 It is a longitudinal cross-sectional view of the swab handle of Example 2 of the present invention.

[0039] Figure 8 It is a front view of the swab head according to embodiment 3 of the present invention.

[0040] Fig. 9 It is a front view of the cutting structure of embodiment 4 of the present invention.

[0041] Fig.10 for Fig. 9 A longitudinal cross-sectional view of part B.

[0042] Fig.11 It is a top view of the cutting structure of embodiment 4 of the present invention.

[0043] Fig.12 This is a bottom view of the fixing portion of embodiment 4 of the present invention.

[0044] Fig.13 This is a bottom view of the cutting structure of Example 4 of the present invention.

[0045] Fig.14 for Fig. 9 CC cross-section diagram.

[0046] Fig.15 It is a longitudinal cross-sectional view of the swab head according to embodiment 5 of the present invention.

[0047] Fig.16 It is a front view of the swab handle of Example 5 of the present invention.

[0048] Fig.17 It is a longitudinal cross-sectional view of the swab handle of Example 5 of the present invention.

[0049] Fig.18 It is a longitudinal cross-sectional view of a local swab head according to embodiment 6 of the present invention.

[0050] Fig.19 It is a longitudinal cross-sectional view of the swab handle of Example 6 of the present invention. DETAILED DESCRIPTION

[0051] The following is further described in detail through specific implementation methods:

[0052] The reference numerals in the drawings of the specification include: inferior nasal meatus 1, nasal vestibule 2, inferior turbinate 3, middle nasal meatus 4, middle turbinate 5, superior turbinate 6, superior nasal meatus 7, nasopharynx 8, hard palate 9, soft palate 10, swab head 11, connecting rod 12, swab handle 13, center rod 14, sponge layer 15, first top sheet 16, first through hole 17, spherical cover 18, indicator light 19, first wire 20, second wire 21, side wall of swab handle 22, second top sheet 23, second through hole 24, upper metal sheet 25, lower metal sheet 26, first bottom sheet 27, limit sheet 28, button battery 29, first spring 30, second A guide portion 31, a first limiting portion 32, a second guide portion 33, a second limiting portion 34, a connecting strip 35, a swab head portion I 36, a swab head portion II 37, a fixing portion 38, a first slider 39, a first slide groove 40, a second slide groove 41, a square through hole 42, a cutting knife 43, a second film 44, a film through hole 45, a second slider 46, a second spring 47, a capillary 48, an airbag 49, a strip window 50, an trachea 51, a pushing piece 52, a trachea limiting piece 53, a pneumatic rod 54, a piston 55, a connecting piece 56, a sampling sleeve 57, a sampling wire 58, a metal wire 59, and a supporting piece 60.

[0053] Example 1

[0054] First, a brief description of the nasal cavity structure and the sampling process of the prior art is given: For nasal cavity structure, see Figure 1 The midsagittal section of the nasal cavity shows that there are inferior turbinate 3, middle turbinate 5 and superior turbinate 6 in the nasal cavity, as well as the corresponding inferior nasal meatus 1, middle nasal meatus 4 and superior nasal meatus 7. Among them, the use of nasopharyngeal swabs for sample collection is to insert the nasopharyngeal swab into the inferior nasal meatus 1. The inferior nasal meatus 1 is a passage surrounded by the hard palate 9, the soft palate 10 and the inferior turbinate 3. One end of the inferior nasal meatus 1 opens to the nasal vestibule 2 (the opening is called the entrance of the inferior nasal meatus 1), and the other end opens to the nasopharynx 8. The process of using the nasopharyngeal swab of the prior art to sample the nasopharynx 8 is as follows: insert the head of the nasopharyngeal swab into the inferior nasal meatus 1 through the nostril and the nasal vestibule 2 until the head of the nasopharyngeal swab reaches the nasopharynx 8, stay for a while and gently rotate the nasopharyngeal swab, then take out the nasopharyngeal swab to complete the sampling. Finally, put the nasopharyngeal swab into a test tube containing the virus transport medium, break the stem of the nasopharyngeal swab, cover the test tube cap, and transport the test tube containing the nasopharyngeal swab to the designated nucleic acid testing laboratory for testing. By Figure 1It can be seen that the structure of the nasal cavity is relatively complex. If an inexperienced person performs sampling (such as self-sampling by a patient), the nasopharyngeal swab may be inserted into the wrong cavity, for example, the nasopharyngeal swab is inserted into the nasal cavity in a direction parallel to the face (correctly, it should be perpendicular to the face), so that the head of the nasopharyngeal swab cannot reach the nasopharynx 8, and the sampling fails. In addition, patients (or suspected patients) who come for sampling usually have some discomfort symptoms (such as upper respiratory tract infection) and swelling inside the nasal cavity, which creates greater difficulties and obstacles to finding the correct nasopharyngeal swab insertion channel and inserting the nasopharyngeal swab into the inferior nasal cavity 1.

[0055] The nasopharyngeal swab self-service collection kit of this embodiment is formed by adding a guide structure to the nasopharyngeal swab of the prior art. The nasopharyngeal swab is a swab commonly used in the prior art and will not be described in detail here. Its general structure is as follows: Figure 2 As shown, the swab head 11, the connecting rod 12 and the swab handle 13 are included. The connecting rod 12 is made of PVC material, which has a certain hardness and can support and push the swab head 11 through the passage in the nasal cavity into the nasopharynx 8. The connecting rod 12 of PVC material has a certain flexibility and can be slightly bent to adapt to the shape of the passage in the nasal cavity.

[0056] Because patients without sampling experience (suspected patients) usually find it difficult to find the opening of the inferior nasal meatus 1 toward the nasal vestibule 2 (i.e., the entrance of the inferior nasal meatus 1), it is easy to insert the nasopharyngeal swab in a direction parallel to the face, the sampling site is wrong, and sampling in the nasopharynx 8 cannot be achieved. The guide structure of this embodiment can assist patients (suspected patients) to find the opening of the inferior nasal meatus 1 toward the nasal vestibule 2. In addition, there are many nasal hairs distributed near the nostrils and on the inner wall of the nasal vestibule 2, and a large amount of secretions containing pollutants (dust, bacteria, viruses, etc.) are adsorbed on the nasal hairs. If the swab head 11 is contaminated with secretions containing the above-mentioned pollutants, it may affect the sampling and detection results and reduce the accuracy of the detection. In addition, after the swab head 11 is contaminated with secretions containing pollutants, if it goes deep into the nasopharynx 8, the swab head 11 may bring pathogenic substances such as bacteria and viruses to the nasopharynx 8, which may cause infection. In addition, there are many sensory nerve endings distributed near the nostrils and on the inner wall of the nasal vestibule 2. The swab head 11 may irritate the nasal cavity of the patient (suspected patient), causing sneezing, increased nasal secretions, etc., affecting the smooth progress of sampling. If the patient (suspected patient) has symptoms of upper respiratory tract infection and swollen nasal cavity, it will further increase the difficulty of inserting the nasopharyngeal swab into the inferior nasal cavity 1.

[0057] like Figure 3 and Figure 4As shown, the guide structure (made of soft silicone material) of the present scheme includes two guide substructures (a first guide substructure and a second guide substructure), each of which includes a bent (semi-C-shaped) tubular guide portion and a limiting portion. More specifically, the first guide substructure includes an integrally formed first guide portion 31 and a first limiting portion 32, and the second guide substructure includes an integrally formed second guide portion 33 and a second limiting portion 34. The first guide portion 31 and the second guide portion 33 are both C-shaped curved pipes, and the first limiting portion 32 and the second limiting portion 34 are both trumpet-shaped. The bottom ends of the first limiting portion 32 and the second limiting portion 34 are connected together by a connecting strip 35, and the connecting strip 35 is integrally formed with the first limiting portion 32 and the second limiting portion 34. When in use, the first guide part 31 and the second guide part 33 of the guide structure are first inserted into the bilateral nostrils. Since the length of the first guide part 31 is about 1 cm and has a curvature, if the opening of the first guide part 31 away from the first limiting part 32 is inserted into the nostril toward the face of the patient (suspected patient), the opening can be inserted into the entrance of the inferior nasal passage 1. The second guide part 33 is the same as the first guide part 31. The first limiting part 32 and the second limiting part 34 can prevent the first guide part 31 and the second guide part 33 from being inserted too deep into the nostril. After the guide structure is inserted into the nostril, a nasopharyngeal swab is used for sampling, and the swab head 11 is inserted into the first limiting part 32. Through the guiding effect of the guide structure, the swab head 11 can be smoothly inserted into the inferior nasal passage 1. The guide structure plays the following roles: assisting the patient (suspected patient) to find the entrance of the inferior nasal passage 1; preventing pollutants near the nostrils and on the inner wall of the nasal vestibule 2 from contaminating the swab head 11; preventing the swab head 11 from irritating the nasal cavity (especially the nasal cavity near the nasal vestibule 2).

[0058] Embodiment 2:

[0059] This embodiment is basically the same as Embodiment 1, except that, in this embodiment, improvements are made to the nasopharyngeal swab in the prior art.

[0060] The nasopharyngeal swab self-collection kit of this program includes: Figure 5 The nasopharyngeal swab shown in the figure includes three parts: a swab head 11, a connecting rod 12 and a swab handle 13. The connecting rod 12 is a hollow cylindrical straight tube with two ends open. The connecting rod 12 is made of PVC and can support and push the swab head 11 through Figure 1 The passage in the nasal cavity shown enters the nasopharynx 8, and the connecting rod 12 made of PVC has a certain flexibility and can be slightly bent to adapt to the shape of the passage in the nasal cavity. Figure 6The cylindrical tubular center rod 14 with two ends open is shown. The material and diameter of the center rod 14 are consistent with the connecting rod 12. In this scheme, the center rod 14 and the connecting rod 12 are integrally formed. The center rod 14 is wrapped with a sponge layer 15 (that is, the outer layer of the swab head 11 is the sponge layer 15). To prevent the sponge layer 15 from falling off, the sponge layer 15 is bonded to the center rod 14. The length of the center rod 14 covered by the sponge layer 15 is 2 cm. A circular first top sheet 16 is bonded and fixed to one end of the center rod 14 away from the connecting rod 12, and a first through hole 17 is opened at the center of the first top sheet 16. An indicator light 19 is bonded and fixed to the upper surface of the first top sheet 16. The indicator light 19 is electrically connected to a first wire 20 and a second wire 21. The first wire 20 and the second wire 21 both pass through the first through hole 17 and enter the center rod 14. The indicator light 19 is covered with a spherical cover 18 on the outside, and the spherical cover 18 is made of transparent PC plastic material. The spherical cover 18 is hemispherical and has a smooth outer surface, which facilitates the swab head 11 to pass through the nasal cavity and prevents the top of the swab head 11 from poking the inner wall of the nasal cavity.

[0061] The structure of the swab handle 13 is as follows Figure 7 As shown, the swab handle 13 is formed by a cylindrical swab handle side wall 22, a second top sheet 23 and a first bottom sheet 27, and the swab handle side wall 22 is bonded and fixed to the second top sheet 23 and the first bottom sheet 27 respectively. A second through hole 24 is provided at the center of the second top sheet 23, and a first wire 20 and a second wire 21 are passed through the second through hole 24. The upper surface of the second top sheet 23 is bonded and fixed to the connecting rod 12, and the connecting rod 12 is connected to the swab handle 13 through the second through hole 24. A lower metal sheet 26 is bonded to the upper surface of the first bottom sheet 27, and a first spring 30 is welded above the lower metal sheet 26, and the lower metal sheet 26 and the first spring 30 are electrically connected. An upper metal sheet 25 is provided above the lower metal sheet 26, and the four sides of the upper metal sheet 25 are inserted into the inner surface of the swab handle side wall 22, and the upper metal sheet 25 is bonded to the swab handle side wall 22. A button battery 29 (TELESKY AG4, diameter 6.8 mm, thickness 2.6 mm, positive pole facing upward) is placed between the lower metal sheet 26 and the upper metal sheet 25. The lower metal sheet 26 is electrically connected to the first wire 20, and the upper metal sheet 25 is provided with a hole for the first wire 20 to pass through (not shown in the figure), and the upper metal sheet 25 and the first wire 20 are insulated, and the second wire 21 is electrically connected to the upper metal sheet 25. A limiting plate 28 is provided between the button battery 29 and the upper metal sheet 25, and a hole for the limiting plate 28 to pass through is provided on the side wall 22 of the swab handle. When the swab is not used, the limiting plate 28 is isolated between the button battery 29 and the upper metal sheet 25, the circuit is not powered, and the indicator light 19 is off. When the nasopharyngeal swab needs to be used for sampling, it is only necessary to pull out the limiting plate 28.

[0062] The novel coronavirus nasopharyngeal swab self-collection kit of this scheme also includes a covered test tube, which contains virus culture fluid. A novel coronavirus nasopharyngeal swab self-collection kit contains two nasopharyngeal swabs, because bilateral sampling is required to increase sampling accuracy. In addition to the test tube and nasopharyngeal swab, in order to facilitate the operation of patients (suspected patients), this kit also contains two pieces of alcohol cotton, which are used to wipe the hands and around the nostrils before use. Since patients (suspected patients) are not familiar with the nasopharyngeal swab sampling operation, this kit must also be equipped with instructions for use. The nasopharyngeal swab, test tube, alcohol cotton and instructions for use are all packaged in a box.

[0063] The specific implementation process is as follows: When the patient (suspected patient) needs to take a sample of the nasopharyngeal secretions 8, take the nasopharyngeal swab of this scheme, hold the swab handle 13, take out the limit piece 28, the circuit is connected, and the indicator light 19 is on. Insert the swab head 11 from the patient's nostril through the guide structure (see Example 1 for details) (the swab head 11 has been soaked with physiological saline at this time), and insert the swab head 11 into the inferior nasal meatus 1 until the swab head 11 enters the nasopharynx 8. For patients (suspected patients) who have no operating experience, it is usually difficult to distinguish whether the swab head 11 is inserted into the nasopharynx 8. At this time, the patient (suspected patient) can open his mouth and face the mirror or mobile phone to observe whether there is a light signal emitted by the indicator light 19 in the pharynx. If the light signal of the indicator light 19 can be observed, it means that the swab head 11 has entered the nasopharynx 8 and the sampling site is correct. The swab head 11 is allowed to stay in the nasopharynx 8 for 15-30 seconds, and then the nasopharyngeal swab is gently rotated left and right. After the sampling is completed, the nasopharyngeal swab is taken out, and the nasopharyngeal swab is placed in a test tube containing a virus culture solution (the virus culture solution infiltrates the swab head 11). The connecting rod 12 of the nasopharyngeal swab is shortened with scissors (because there is a wire in the connecting rod 12, it cannot be directly broken like a general swab) to complete the unilateral sampling. Then use the same method to sample the other nostril. After completing the bilateral sampling, cover the test tube cap, complete the sampling, and send the sample to the designated testing laboratory for nucleic acid testing.

[0064] In addition, the diameter of the swab handle 13 is larger than the diameter of the connecting rod 12, and the sum of the lengths of the connecting rod 12 and the center rod 14 is about 6 cm. When the upper surface of the swab handle 13 contacts the nose wing, it also indicates that the swab head 11 has reached the nasopharynx 8. In addition to being convenient for holding and placing batteries, the swab handle 13 also has the function of indicating the insertion depth of the nasopharyngeal swab. The swab handle 13 indicates the insertion depth, and the indicator light 19 reminds the patient (suspected patient) that the swab head 11 has entered the nasopharynx 8, ensuring that sampling is performed in the correct position.

[0065] Example 3

[0066] This embodiment is basically the same as the embodiment 2, except that the structure of the swab head 11 is different. In this embodiment, the swab head 11 is bent. Figure 8 As shown, the swab head 11 includes a swab head part I 36 and a swab head part II 37, and there is an obtuse angle between the two. More specifically: the central rod 14 includes an integrally formed rod part I and rod part II (not shown in the figure), and there is an obtuse angle between rod part I and rod part II, and then a sponge layer 15 is coated on the outer side of the bent central rod 14. When in use, the swab head 11 is inserted into the inferior nasal cavity 1 with the swab head part I 36 facing downward and the swab head part II 37 perpendicular to the human face. Since the soft palate 10 has an arc, the swab head 11 is bent to better fit the arc of the soft palate 10. Compared with the straight swab head 11, this solution can allow the swab head 11 to penetrate deeper into the nasopharynx 8, and the sampling is more accurate. In addition, the indicator light 19 of the bent swab head 11 of this solution can point to the epiglottis of the patient (suspected patient), and when the mouth is opened, the light signal of the indicator light 19 can be more easily observed.

[0067] Example 4

[0068] This embodiment is basically the same as Embodiment 1, except that, in order to facilitate breaking of the connecting rod 12, a cutting structure is also provided in this solution. Since the first wire 20 and the second wire 21 are inserted into the connecting rod 12, the connecting rod 12 cannot be broken by directly breaking it, and it is necessary to prepare additional cutting tools such as scissors or knives to achieve the cutting of the connecting rod 12. In addition, in this solution, there are batteries in the swab handle 13, and the battery treatment method is different from other medical wastes. It is very necessary to treat the swab handle 13 containing batteries separately from other parts. Therefore, this embodiment specially provides a cutting structure, such as Fig. 9 As shown, the cutting structure includes a fixing portion 38 and two left and right first sliders 39. The fixing portion 38 is a cylindrical structure. Fig.12 As shown, first slide grooves 40 are respectively provided on the left and right sides of the lower surface of the fixing portion 38, and the first slide grooves 40 on the left and right sides are symmetrically distributed with the central axis of the fixing portion 38 as the symmetry axis. Second slide grooves 41 are provided on the upper and lower sides of the first slide groove 40. A rectangular square through hole 42 is provided in the center of the fixing portion 38, and the square through hole 42 is for the connecting rod 12 to pass through. Fig. 9 and Fig.13 As shown, the lower surface of the fixing portion 38 is bonded and fixed to the swab handle 13. Specifically, the lower surface of the fixing portion 38 is bonded and fixed to the upper surface of the second top sheet 23, and the square through hole 42 is connected to the second through hole 24. Fig.14 As shown, the first slider 39 is slidably connected in the first slide groove 40, and the upper and lower sides of the first slider 39 are integrally formed with the second slider 46, the second slider 46 slides in the second slide groove 41, and the second slider 46 is bonded and fixed with a second spring 47, and one end of the second spring 47 away from the corresponding second slider 46 is bonded and fixed to the side wall of the second slide groove 41. Fig. 9 As shown, the lower surface of the first sliding block 39 is flush with the lower surface of the fixing portion 38. Fig.10 As shown, a cutting knife 43 is fixed to one end of the first slider 39 close to the connecting rod 12 (the cutting knife 43 is inserted into the first slider 39 and bonded to the first slider 39), and the left and right cutting knives 43 are located on the same horizontal plane. In this scheme, the connecting rod 12 is connected to the swab handle 13 through a thin tube 48, specifically: a circular second bottom film 44 is bonded below the connecting rod 12, a bottom film through hole 45 is provided at the center of the second bottom film 44, the lower surface of the second bottom film 44 is bonded to the thin tube 48, and the lower end of the thin tube 48 is bonded to the second top film 23. The blades of the left and right cutting knives 43 are both facing the thin tube 48. After the sampling is completed, the swab head 11 of the nasopharyngeal swab is inserted into the test tube, and then the first sliders 39 on the left and right sides are pressed at the same time, and the two cutting knives 43 cut off the thin tube 48, and the swab handle 13 is recovered, and the swab handle 13 will be used for harmless treatment.

[0069] like Fig.11 As shown, in this solution, the four side walls of the square through hole 42 are tangent to the side walls of the connecting rod 12, which supports and stabilizes the connecting rod 12. The capillary 48 is easier to cut than the connecting tube, but its strength is limited, and it is possible that irreversible bending occurs during use, making it impossible for the sampling process to proceed normally. The setting of the cutting structure (square through hole 42) can prevent the capillary 48 from irreversible bending due to the limiting effect of the square through hole 42. And during cutting, since the connecting rod 12 is limited, the capillary 48 fixed to the connecting rod 12 is fixed between the two cutting knives 43, and will not be displaced, so that more stable and effective cutting can be achieved.

[0070] In this scheme, if Fig. 9 As shown, the diameter of the fixing portion 38 is larger than the diameter of the swab handle 13. As the fixing portion 38 is enlarged, it can be stuck outside the nostril, which can more effectively remind the patient (suspected patient) the depth of the swab head 11 inserted into the nasal cavity, preventing the patient (suspected patient) from continuing to insert the nasopharyngeal swab into the nasal cavity, and avoiding damage to the nasal cavity caused by the sampling operation. In addition, the cutting structure of this embodiment can also be directly applied to the nasopharyngeal swab of the prior art (such as the nasopharyngeal swab in Example 1).

[0071] Example 5

[0072] This embodiment is an improvement on the basis of embodiment 1, and the specific structure of the nasopharyngeal swab is improved to optimize the sampling process. Figure 15-17 As shown. Fig.15As shown, the swab head 11 includes a hollow central rod 14, the upper part of the central rod 14 is open, and a connecting piece 56 is bonded and fixed to the lower part of the central rod 14. A through hole is provided on the connecting piece 56, and a trachea 51 (silicone hose) passes through the through hole, and the trachea 51 is bonded and fixed to the connecting piece 56. The lower surface of the connecting piece 56 is bonded and fixed to the connecting rod 12. A trachea limiting piece 53 is bonded and fixed to the upper end of the trachea 51, and a through hole is also provided in the trachea limiting piece 53, and a push structure is slidably connected in the through hole, specifically: the push structure includes a push piece 52, a pneumatic rod 54 and a piston 55, and the three are integrally formed. The piston 55 is located in the trachea 51, and the piston 55 is slidably and sealedly connected to the inner wall of the trachea 51, the pneumatic rod 54 is inserted in the through hole in the trachea limiting piece 53, and the push piece 52 is connected to a brush-like sampler. The brush-like sampler includes a sampling sleeve 57 and a metal wire 59. The cotton sampling sleeve 57 is set and bonded on the metal wire 59. The metal wire 59 is soft and deformable. The sampling sleeve 57 includes a cotton sampling wire 58, that is, the cotton thread of the woven sampling sleeve 57 extends outward to form the sampling wire 58. One end of the metal wire 59 is bonded and fixed to the push piece 52. The trachea 51 runs through the entire connecting rod 12 and is inserted into the swab handle 13 (such as Fig.16 and Fig.17 As shown). The swab handle 13 is formed by a cylindrical swab handle side wall 22, a second top sheet 23 and a first bottom sheet 27. The swab handle side wall 22 is bonded and fixed to the second top sheet 23 and the first bottom sheet 27 respectively. A second through hole 24 is provided at the center of the second top sheet 23. An air tube 51 is passed through the second through hole 24. The lower end of the air tube 51 is connected to an air bag 49. The air tube 51 is bonded and fixed to the air bag 49 (the air tube 51 and the air bag 49 form a power structure). As shown Fig.16 As shown, two strip windows 50 are provided on the swab handle 13, and the user can press the air bag 49 through the strip windows 50. In this embodiment, the center rod 14 is not wrapped with any sponge or other structures, which minimizes the stimulation to the nasal cavity. The distance from the top of the center rod 14 to the top of the swab handle 13 is 5cm. When the top of the center rod 14 is close to the nasopharynx 8, the air bag 49 is pressed to push the brush sampler out of the swab head 11, and the state of pressing the air bag 49 is maintained, so that the brush sampler is maintained in the nasopharynx 8 for a period of time (staying for 15-20 seconds and then rotating the swab handle 13 for three weeks) to fully sample. Then, release the air bag 49, and the brush sampler is retracted into the center rod 14. In this way, the sampling is completed. In the process of taking out the nasopharyngeal swab, the brush sampler will not contact the inner wall of the nasal passage, reducing the contamination of the inner wall of the nasal passage to the sample on the brush sampler.

[0073] Example 6

[0074] This embodiment is basically the same as the embodiment 5, except that the indicator light 19 of the embodiment 2 is added to the embodiment. The specific structure is as follows: Fig.18As shown, a carrier sheet 60 is integrally formed on the top of the center rod 14, and the indicator light 19 is bonded and fixed on the carrier sheet 60. Since the sampling wire 58 on the brush sampler is made of cotton and soft, the sampling wire 58 of the brush sampler will be deformed when passing through the carrier sheet 60, and the entire brush sampler will not be stuck in the center rod 14. Fig.19 As shown, a battery is also provided below the airbag 49, specifically as follows: a lower metal sheet 26 is bonded to the upper surface of the first bottom sheet 27, a first spring 30 is welded above the lower metal sheet 26, and the lower metal sheet 26 is electrically connected to the lower metal sheet 26. An upper metal sheet 25 is provided above the lower metal sheet 26, the periphery of the upper metal sheet 25 is inserted into the inner surface of the swab handle side wall 22, and the upper metal sheet 25 is bonded to the swab handle side wall 22. A button battery 29 (TELESKY AG4, diameter 6.8mm, thickness 2.6mm, positive pole facing upward) is placed between the lower metal sheet 26 and the upper metal sheet 25. A limiting plate 28 is provided between the button battery 29 and the upper metal sheet 25, and a hole is provided on the swab handle side wall 22 for the limiting plate 28 to pass through. The button battery 29 is electrically connected to the indicator light 19 in the manner of the prior art. When the swab is not used, the limiting piece 28 is isolated between the button battery 29 and the upper metal sheet 25, the circuit is not powered, and the indicator light 19 is not lit. When the nasopharyngeal swab needs to be used for sampling, the limiting piece 28 only needs to be pulled out.

[0075] The above is only an embodiment of the present invention, and the common knowledge such as the known specific structure and characteristics in the scheme is not described in detail here. It should be pointed out that for those skilled in the art, several deformations and improvements can be made without departing from the structure of the present invention, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A nasopharyngeal swab self-service collection kit, comprising a nasopharyngeal swab, characterized in that: It also includes a guide structure, the guide structure includes two guide substructures, the guide substructure includes a limit portion and a bent tubular guide portion, the guide portion is used to guide the nasopharyngeal swab into the lower nasal passage; The nasopharyngeal swab comprises a swab head, a connecting rod and a swab handle which are arranged in sequence and connected; An indicator light is provided on the top of the swab head; the indicator light is used to emit a light signal from the patient's pharynx, and the light signal is observed by the patient opening his mouth and facing a mirror or a mobile phone; The swab handle is formed by a cylindrical swab handle side wall, a second top sheet and a first bottom sheet; a second through hole is provided at the center of the second top sheet, and a first wire and a second wire are passed through the second through hole; a lower metal sheet is bonded to the upper surface of the first bottom sheet, a first spring is welded above the lower metal sheet, and the lower metal sheet and the first spring are electrically connected; an upper metal sheet is provided above the lower metal sheet, the four sides of the upper metal sheet are inserted into the inner surface of the side wall of the swab handle, and the upper metal sheet is bonded to the side wall of the swab handle; a button battery is placed between the lower metal sheet and the upper metal sheet; the lower metal sheet is electrically connected to the first wire, and the second wire is electrically connected to the upper metal sheet; a limiting plate is provided between the button battery and the upper metal sheet, and a hole for the limiting plate to pass through is provided on the side wall of the swab handle; A cutting structure is provided between the connecting rod and the swab handle; the cutting structure includes a fixing part and two first left and right sliding blocks; the lower surface of the fixing part is bonded and fixed to the swab handle, and a rectangular square through hole is provided in the center of the fixing part, and the square through hole is for the connecting rod to pass through; the connecting rod is connected to the swab handle through a capillary; first slide grooves are respectively provided on the left and right sides of the lower surface of the fixing part, and second slide grooves are provided on the upper and lower sides of the first slide groove; the first slide groove is slidably connected in the first slide groove, and the upper and lower sides of the first slide groove are integrally formed with the second slide groove, and the second slide groove slides in the second slide groove, and the second slide groove is bonded and fixed with a second spring, and the end of the second spring away from the corresponding second slide groove is bonded and fixed to the side wall of the second slide groove; a cutting knife is fixed to the end of the first slide groove close to the connecting rod, and the left and right cutting knives are located on the same horizontal plane; the blades of the left and right cutting knives are both facing the capillary tube.

2. The nasopharyngeal swab self-service collection kit according to claim 1, characterized in that: The guide substructure further comprises a limiting portion, which is located at an end of the guide portion away from the entrance of the inferior nasal passage.

3. The nasopharyngeal swab self-service collection kit according to claim 2, characterized in that: The number of the guide structures is two.

4. The nasopharyngeal swab self-service collection kit according to claim 3, characterized in that: The guide structure is made of silicone.

5. The nasopharyngeal swab self-service collection kit according to any one of claims 1 to 4, characterized in that: The outer cover of the indicator light has a spherical cover.

6. The nasopharyngeal swab self-service collection kit according to any one of claims 1 to 4, characterized in that: A brush-shaped sampler is arranged in the swab head, and the brush-shaped sampler is slidably connected with the inner wall of the swab head.

7. The nasopharyngeal swab self-service collection kit according to claim 6, characterized in that: The nasopharyngeal swab is also provided with a driving structure and a power structure; one end of the brush-shaped sampler is fixed on the driving structure, the power structure includes a trachea and an air bag, and the driving structure includes a piston; the piston is slidably and sealingly connected to the inner wall of the trachea.

8. The nasopharyngeal swab self-service collection kit according to claim 7, characterized in that: The diameter of the swab handle is greater than the diameter of the connecting rod.

9. The nasopharyngeal swab self-service collection kit according to claim 5, characterized in that: The swab head comprises a swab head part I and a swab head part II, and an obtuse angle is formed between the swab head part I and the swab head part II.

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