A cryogenic tube suction device for deep cryogenics

By designing a freezing storage tube suction device for deep and low temperatures, the coordinated work of the clamping assembly and driving mechanism is used to solve the problem of unstable positioning and easy drop in the deep and low temperature environment, and the stable clamping and vertical positioning of the freezing storage tube are achieved, ensuring the safe storage of the freezing storage tube and the normal operation of the equipment.

CN112090469BActive Publication Date: 2025-04-04SUZHOU BEIKANG INTELLIGENT MFG CO LTD

Patent Information

Application Number
CN202010985920.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-09-18
Publication Date
2025-04-04
Estimated Expiration
2040-09-18

AI Technical Summary

Technical Problem

In deep and low temperature environments, traditional clamping tools can easily lead to contamination of frozen storage tubes and failure of electronic components, while vacuum straws have problems such as unstable positioning of frozen storage tubes and easy drop.

Method used

A freezing tube suction device for deep and low temperatures is designed, including a vacuum assembly, a straw assembly, a sleeve fitting, a clamping assembly and a drive mechanism. When the straw assembly rises, the clamping assembly clamps the frozen storage tube to ensure its vertical position and stable clamping; when the straw assembly descends, the clamping assembly releases the frozen storage tube. The heating module provides a temperature-friendly environment to ensure the normal operation of the drive mechanism.

Benefits of technology

The stable clamping and vertical positioning of the frozen storage tube is achieved, which avoids the fall and contamination of the frozen storage tube, ensures the safe storage of the frozen storage tube, and extends the service life of the drive mechanism.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to a cryopreservation tube suction device for deep low temperature, comprising: a vacuum component; a straw component connected to the vacuum component and used to suck products; a sleeve member sleeved outside the straw component; a clamping component connected between the straw component and the sleeve member, and after the straw component sucks the product, the clamping component clamps the product. A driving mechanism is connected to the straw component and is used to drive the straw component to rise or fall in the sleeve member; the straw component can be lowered and extended outside the sleeve member to suck the product, and after the product is sucked, the straw component rises and retracts into the sleeve member, while driving the product to move upward, so that part of the product enters the sleeve member, and the clamping component will start to clamp and fix the product to prevent the cryopreservation tube from falling. When releasing the product, the straw component descends and the clamping component releases the product. Before releasing the product, the clamping component always clamps the product so that the product is in a vertical position, which is convenient for the tube release operation.
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Description

Technical Field

[0001] The invention relates to the technical field of clamping tools, in particular to a deep-cryogenic cryopreservation tube suction device. Background Art

[0002] Biological samples are usually stored in a low-temperature environment, which can maintain the biological activity of biological samples and improve the survival and development ability of biological samples after freezing and resuscitation. Specifically, biological samples are usually stored in cryogenic tubes. During the storage process, the cryogenic tubes need to be moved using a clamping device according to the changes in the storage and extraction positions. Traditional clamping devices require a large number of mechanical moving parts and electronic components to achieve the clamping action. However, in a deep low-temperature environment, mechanical moving parts are not easy to lubricate, so it is easy to contaminate the cryogenic tubes during lubrication. Electronic components have poor low-temperature resistance and are prone to failure and damage.

[0003] Using a vacuum pipette to suck up cryotubes is a method that is less dependent on mechanical moving parts and electronic components. The cryotubes are sucked and clamped by the pipette, but the positioning of the cryotubes sucked up by the pipette is not stable enough, and the cryotubes are easily not in a vertical state, resulting in tube storage failure. In addition, when the vacuum fails or is destroyed, the cryotubes are prone to fall, causing damage to the cryotubes. Summary of the invention

[0004] Based on this, it is necessary to provide a deep-low temperature cryotube suction device to address the above-mentioned problems. After sucking the cryotube, the vertical position of the cryotube can be maintained and the cryotube can be stably clamped to prevent the cryotube from falling, thereby facilitating the storage of the cryotube.

[0005] A cryopreservation tube suction device for deep cryogenics, comprising:

[0006] Vacuum components;

[0007] A suction tube assembly, connected to the vacuum assembly, for sucking the product;

[0008] A sleeve member, sleeved outside the straw assembly;

[0009] A clamping assembly, disposed between the straw assembly and the sleeve member, the clamping assembly being connected to the straw assembly and being linked to the straw assembly;

[0010] A driving mechanism, connected to the straw assembly, and used for driving the straw assembly to rise or fall in the sleeve member;

[0011] A heating module, used to provide a suitable temperature working environment for the driving mechanism;

[0012] When the straw assembly rises and a portion of the product enters the sleeve, the clamping assembly clamps the product;

[0013] When the straw assembly is lowered, the clamping assembly releases the product.

[0014] In the above-mentioned deep-cryogenic cryotube suction device, the straw assembly can extend out of the sleeve to suck the product. After the product is sucked, the driving mechanism can control the straw assembly to rise, so that the straw assembly retracts into the sleeve, and at the same time drives the product to move upward, so that part of the product enters the sleeve. When the straw assembly rises and part of the product enters the sleeve, the clamping assembly will start to clamp the product to prevent the cryotube from falling. When placing the product, the straw assembly descends and the clamping assembly releases the product. Before releasing the product, the clamping assembly always clamps the product so that the product is in a vertical position, which is convenient for the tube placement operation. The heating module can provide a suitable temperature working environment for the driving mechanism in a deep-cryogenic environment to ensure the normal operation of the driving mechanism.

[0015] In one embodiment, the clamping assembly includes: a plurality of clamping members respectively arranged around the straw assembly, each of the clamping members is connected to the straw assembly, and when the straw assembly rises, the clamping members are driven to approach each other; when the straw assembly descends, the clamping members are driven to move away from each other. The number of clamping members can be 3, and the cryopreservation tube is clamped from three directions in the horizontal direction so that the cryopreservation tube is in a vertical position. The provision of multiple clamping members can stabilize the position of the product and ensure stable clamping.

[0016] In one embodiment, the straw assembly comprises:

[0017] A straw connected to the driving mechanism;

[0018] A suction head cover is arranged in the sleeve member and sleeved outside the suction tube, and the suction head cover and the suction tube can be relatively slidably matched;

[0019] The straw has a first position and a second position when it moves upward. When the straw moves upward to the first position, the straw and the suction head cover abut against each other in the axial direction, and the straw can drive the suction head cover to move.

[0020] During the process of the straw moving from the first position to the second position, the suction head cover is driven to move upward, and the suction head cover drives the clamping assembly to clamp the product. The straw moves upward, and before it moves a certain distance to reach the first position, the clamping assembly will not be activated, so as to facilitate the cryopreservation tube to enter the appropriate position in the suction head cover; after the straw reaches the first position, the cryopreservation tube reaches the appropriate position in the suction head cover, and the straw continues to move upward, which will drive the cryopreservation tube and the suction head cover to move upward synchronously, and the clamping assembly is activated by the movement of the suction head cover, and the clamping assembly can clamp and fix the cryopreservation tube in the appropriate position.

[0021] In one embodiment, the peripheral side of the pipette cover is provided with: a plurality of through slots, the number of which is the same as the number of the clamping members and corresponds one to one, and each of the clamping members is respectively arranged in a corresponding through slot, and when each of the clamping members approaches each other, they respectively enter the pipette cover through their respective corresponding through slots to clamp the product. The holding member is located in the through slot, so that the movement trajectory of the clamping member is stable, and the through slot also defines the position of the clamping member, so that the clamping and positioning of the cryopreservation tube is more stable.

[0022] In one of the embodiments, a guide groove is provided on the inner wall of the sleeve member, and the guide groove is connected with the through groove to form a connecting space. The clamping member is a ball disposed in the connecting space. When the suction head cover rises, the groove wall of the guide groove pushes the clamping member toward the inside of the suction head cover.

[0023] In one embodiment, the guide groove has: a first wall, a guide wall and a second wall arranged from bottom to top, when the ball is against the first wall, part of it is located in the through groove; when the ball is against the second wall, part of it enters the straw assembly through the through groove; when the suction head cover rises, the ball rolls from the first wall through the guide wall to against the second wall, and the guide wall pushes the ball toward the inside of the straw assembly. The arrangement of the ball and the guide wall has the advantages of simple structure, low cost, good transmission effect and no influence by the deep low temperature environment.

[0024] In one embodiment, the straw comprises: a connection portion connected to the driving mechanism, a suction head portion, and a buffer portion connected between the connection portion and the suction head portion, and the suction head sleeve is mounted on the suction head portion. The straw is a slender structure, and working in a deep low temperature environment will cause the hardness of the straw to be relatively fragile. When the driving mechanism applies an upward or downward force to the straw as a whole, the straw may be damaged. The buffer portion provided between the connection portion and the suction head portion can buffer the force applied by the driving mechanism.

[0025] In one embodiment, the sleeve member is provided with: an elastic reset member, and the elastic reset member is arranged above the tip cover. When the straw moves from the first position to the second position, the tip cover moves up and compresses the elastic reset member. The straw and the tip cover cooperate with each other through the clamping protrusion and the clamping part. The straw can drive the tip cover to move upward, but the clamping direction of the clamping part and the clamping protrusion is vertical. When the straw moves downward, the clamping protrusion and the clamping part of the tip cover will be disengaged and cannot continue to drive the tip cover to move downward. The tip cover remains in place, causing the clamping of the cryopreservation tube to be unable to be unlocked. The provision of the elastic reset member can cause the tip cover to move downward, solving the problem that the straw cannot drive the tip cover to move downward, so that the cryopreservation tube can be smoothly unlocked and released.

[0026] In one embodiment, the side wall of the through groove is an inclined wall, and the inclined wall is used to push the ball into the guide groove. When the suction head cover descends, the inclined wall of the through groove pushes the ball out of the through groove, so that the ball moves in the direction of leaving the through groove, and the ball always abuts against the groove wall of the guide groove, thereby unlocking and releasing the cryotube.

[0027] In one embodiment, the driving mechanism includes: a driving member, a transmission assembly connected between the driving member and the straw assembly, and the transmission assembly is used to drive the straw assembly to rise or fall under the drive of the driving member; the cryogenic tube suction device for deep cryogenic storage also includes: a motor cover, the driving mechanism is arranged in the motor cover, and a heating module is arranged in the motor cover. The motor cover and the bracket form a closed space, the motor is arranged in the closed space, and the motor cover is provided with a heating module. The heating module can emit heat in the closed space, so that the working environment temperature of the motor is raised to a temperature suitable for the motor and electronic components to work, thereby ensuring the working efficiency and working life of the motor. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a schematic diagram of the overall structure of the suction device;

[0029] Figure 2 for Figure 1 The structural diagram at A in the middle;

[0030] Figure 3 It is a schematic diagram of the structure of the suction device when sucking the cryopreservation tube;

[0031] Figure 4 for Figure 3 Schematic diagram of the structure at B in the middle;

[0032] Figure 5 is a schematic diagram of the structure when the straw assembly is in the first position;

[0033] Figure 6 is a schematic diagram of the structure when the straw assembly is in the second position;

[0034] Figure 7 for Figure 6 The structural diagram at C in the middle;

[0035] Figure 8 Schematic diagram of the structure of the straw assembly.

[0036] Wherein: 100, vacuum assembly; 200, straw assembly; 210, straw; 211, buffer part; 212, suction head; 213, snap-on protrusion; 220, suction head cover; 221, snap-on part; 222, through groove; 2221, inclined wall; 300, sleeve member; 310, guide groove; 311, first wall; 312, guide wall; 313, second wall; 320, elastic reset member; 400, clamping assembly; 410, clamping member; 500, cryopreservation tube; 600, driving mechanism; 610, driving member; 611, first gear; 621, second gear; 622, ball spline nut; 623, ball spline shaft; 700, bracket; 800, heating module; 900, motor cover. DETAILED DESCRIPTION

[0037] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0038] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0039] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0040] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0041] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0042] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are for illustrative purposes only and are not intended to be the only implementation method.

[0043] See also Figure 1 , Figure 1The present invention shows a cryogenic tube suction device for deep cryogenics in one embodiment of the present invention, which is used for sucking cryogenic tubes 500 in deep cryogenic environments, and includes: a vacuum assembly 100, a pipette assembly 200, a sleeve assembly 300, and a clamping assembly 400, wherein the vacuum assembly 100 is connected to the pipette assembly 200, and the pipette assembly 200 can suck the product through the suction provided by the vacuum assembly 100. In this embodiment, the product is a cryogenic tube 500. Of course, in other embodiments, the product can also be other types of parts to be sucked, which are not specifically limited in this embodiment. The sleeve assembly 300 is sleeved outside the pipette assembly 200 to protect the pipette assembly 200. The clamping assembly 400 is arranged in the sleeve assembly 300. After the pipette assembly 200 sucks the cryogenic tube 500, the clamping assembly 400 clamps the cryogenic tube 500. When the suction device is working, the cryopreservation tube 500 is sucked from the top of the cryopreservation tube 500, and the suction position of the suction pipe assembly 200 is located at the bottom of the suction pipe assembly 200, wherein the bottom of the suction pipe assembly 200 can be located in the sleeve member 300. After the suction pipe assembly 200 sucks the cryopreservation tube 500, at least part of the cryopreservation tube 500 is located in the sleeve member 300, and the sleeve member 300 can clamp the cryopreservation tube 500, and position and clamp the cryopreservation tube 500. The clamping assembly 400 can be a clamping claw or a clamping column disposed on both sides of the cryopreservation tube 500, etc., which can stably clamp the cryopreservation tube 500, so that the cryopreservation tube 500 is located in a vertical position, which is convenient for taking and placing the cryopreservation tube 500. The clamping claws and the clamping column can be controlled by electronic components and the driving mechanism 600 to automatically clamp the cryopreservation tube 500. The electronic components and the driving mechanism 600 can be arranged above the sleeve 300. The suction device has: a heating module 800. The heating module 800 is arranged close to the driving mechanism 600 and can provide a suitable temperature working environment for the driving mechanism 600 by generating heat. The temperature of the working environment of the driving mechanism 600 can be controlled by a temperature sensor and the heating module 800, so that the driving mechanism 600 can be kept working at a suitable ambient temperature, thereby avoiding failure of the driving mechanism 600 and extending the life of the driving mechanism 600.

[0044] In this embodiment, the suction device further includes: a support 700 and a driving mechanism 600. The driving mechanism 600 is arranged on the support 700. The sleeve 300 is also fixed on the support 700. The driving mechanism 600 is connected to the suction tube assembly 200 and can drive the suction tube assembly 200 to rise or fall in the sleeve 300. In this embodiment, the suction tube assembly 200 can extend out of the sleeve 300 to suck the cryopreservation tube 500. After the suction of the cryopreservation tube 500 is completed, the suction tube assembly 200 can be connected to the sleeve 300 to suck the cryopreservation tube 500. Figure 1 , Figure 3 and Figure 5, the driving mechanism 600 can control the straw assembly 200 to rise, so that the straw assembly 200 is retracted into the sleeve 300, and at the same time drive the cryotube 500 to move upward, so that part of the cryotube 500 enters the sleeve 300. When the straw assembly 200 rises and part of the cryotube 500 enters the sleeve 300, the clamping assembly 400 will start to clamp and fix the cryotube 500. When placing the cryotube 500, the straw assembly 200 descends, and the clamping assembly 400 releases the cryotube 500. Before releasing the cryotube 500, the clamping assembly 400 always clamps the cryotube 500, so that the cryotube 500 is in a vertical position, which is convenient for the tube placement operation.

[0045] Among them Figure 1 and Figure 2As shown, the driving mechanism 600 may include: a driving member 610, a transmission assembly connected between the driving member 610 and the straw assembly 200, and the driving member 610 may be a driving component such as a motor, a cylinder, etc. In this embodiment, the driving member 610 is a motor, specifically a stepping motor, which has the advantages of controllable start and stop, accurate speed control, and the motor can be controlled by electronic components to work. The transmission assembly is connected to the straw assembly 200, and the straw assembly 200 can be driven by the motor to rise or fall. In this embodiment, the output end of the motor is connected to a first gear 611, and the transmission assembly includes: a second gear 621 meshing with the first gear 611, a first rotation displacement member fixed to the second gear 621, and a second rotation displacement member fixedly connected to the sleeve member 300; wherein the first rotation displacement member and the second rotation displacement member can rotate relative to each other, and move up and down relative to each other during relative rotation, and the first rotation displacement member and the second rotation displacement member can be a ball spline shaft 623 and a ball spline nut 622, respectively; or they can be a screw and a screw nut, respectively. In this embodiment, the first rotation displacement member connected to the second gear 621 is a ball spline nut 622, and the second rotation displacement member is a ball spline shaft 623, and the ball spline shaft 623 can be fixedly connected to the straw assembly 200, or be a part of the straw assembly 200. In other embodiments, the positions of the ball spline shaft 623 and the ball spline nut 622 can be interchangeable, which is not specifically limited in this embodiment. When the motor starts, the first gear 611 rotates, driving the second gear 621 meshing therewith to rotate. The second gear 621 is fixed to the ball spline nut 622, driving the ball spline nut 622 to rotate. The ball spline nut 622 and the ball spline shaft 623 rotate relative to each other, causing the ball spline shaft 623 to move upward or downward. The ball spline shaft 623 drives the straw assembly 200 to move up and down, thereby completing the driving of the straw assembly 200. When the motor rotates, it can drive the straw assembly 200 to move up and down through the transmission assembly. It is worth noting that since the use environment of the suction device is a deep low temperature environment, specifically a low temperature environment below -100°C, the working effect and life of the motor and electronic components in a deep low temperature environment will be reduced. In this embodiment, a motor cover 900 is provided on the bracket 700, and the motor cover 900 and the bracket 700 form a closed space. The motor is arranged in the closed space. A heating module 800 is provided in the motor cover 900. The heating module 800 can emit heat in the closed space to increase the working environment temperature of the motor to a temperature suitable for the operation of the motor and electronic components, thereby ensuring the working efficiency and service life of the motor.

[0046] In some embodiments, when the clamping assembly 400 is a structure such as a clamping claw or a clamping column, it can be electrically connected to the electronic components in the motor cover 900, and the electronic components can control it to clamp the cryogenic tube 500 after the pipette assembly 200 rises. The electronic components can control the motor and the clamping assembly 400 at the same time, and can calculate the positions of the pipette assembly 200 and the cryogenic tube 500 through the time and efficiency of the motor rotation, and then control the clamping assembly 400 to clamp, so as to avoid errors in the clamping position.

[0047] In this embodiment, the clamping assembly 400 is disposed between the straw assembly 200 and the sleeve 300, and is linked with the straw assembly 200. When the straw assembly 200 moves upward, the clamping assembly 400 can be directly driven to clamp the cryopreservation tube 500 on the straw assembly 200, thereby achieving automatic clamping, which does not rely on the control of electronic components. Figure 1-Figure 3 As shown, the clamping assembly 400 includes: a plurality of clamping members 410 arranged around the straw assembly 200, each clamping member 410 is connected to the straw assembly 200, and when the straw assembly 200 rises, each clamping member 410 can be driven to approach each other to clamp the cryopreservation tube 500; when the straw assembly 200 descends, each clamping member 410 can be driven to move away from each other to release the cryopreservation tube 500. Preferably, the number of clamping members 410 can be 3, and the cryopreservation tube 500 is clamped from three directions in the horizontal direction so that the cryopreservation tube 500 is in a vertical position. Of course, the number of clamping members 410 can also be 2 or 4 or more, and multiple groups can also be provided, which is not specifically limited in this embodiment. There can be many ways to connect the clamping member 410 and the straw assembly 200. It is preferred that the straw assembly 200 can drive the clamping member 410 to move when it moves up and down. For example, the straw assembly 200 and the clamping member 410 are connected by a connecting rod mechanism, and when the straw assembly 200 rises, each clamping member 410 can be driven to swing inward, and each clamping member 410 can approach each other to clamp the cryopreservation tube 500.

[0048] In this embodiment, if Figure 3 As shown, the pipette assembly 200 includes: a pipette 210 connected to a driving mechanism 600, a pipette head cover 220 sleeved outside the pipette 210, the pipette head cover 220 is located between the pipette 210 and the sleeve member 300, the bottom of the pipette 210 is a pipette head 212, which is used to suck up a cryopreservation tube 500, and the pipette head cover 220 is sleeved on the pipette head 212. After the pipette head 212 sucks up the cryopreservation tube 500, the pipette head cover 220 can protect the cryopreservation tube 500. When the pipette head cover 220 moves upward, the clamping assembly 400 clamps the cryopreservation tube 500 partially located in the pipette head cover 220.

[0049] like Figure 3 and Figure 8As shown, the suction pipe 210 includes: a connecting portion connected to the driving mechanism 600, a suction head 212 for sucking the cryopreservation tube 500, and a buffer portion 211 connected between the connecting portion and the suction head 212. The connecting portion is the above-mentioned ball spline shaft 623, which can move under the drive of the driving mechanism 600. The suction head cover 220 is sleeved on the suction head 212. Since the suction pipe 210 is a slender structure and works in a deep low temperature environment, the hardness of the suction pipe 210 will be relatively fragile. When the driving mechanism 600 applies an upward or downward force to the suction pipe 210 as a whole, the suction pipe 210 may be damaged. The buffer portion 211 provided between the connecting portion and the suction head 212 can buffer the force applied by the driving mechanism 600. In this embodiment, the connecting portion, the suction head 212 and the buffer portion 211 are all hollow tubes to ensure the transmission of vacuum suction. A buffer elastic member is provided in the buffer portion 211, which is a buffer spring in this embodiment, and can certainly be other elastic members, which are not specifically limited in this embodiment. The buffer elastic member can buffer the force applied by the driving mechanism 600 to protect the straw 210 .

[0050] The suction head cover 220 and the suction tube 210 can slide relative to each other. Figure 3 As shown, one of the straw 210 and the suction head cover 220 is provided with a clamping portion 221, and the other is provided with a clamping protrusion 213. In this embodiment, only the straw 210 is provided with a clamping protrusion 213, and the suction head cover 220 is provided with a clamping portion 221 as an example. The positions of the two can be interchanged and are not specifically limited. Figure 3 In the middle position, when the pipette 210 just sucks the cryopreservation tube 500, the pipette 210 and the suction head cover 220 are separated from each other, the clamping protrusion 213 on the pipette 210 and the clamping part 221 on the suction head cover 220 are not matched, and the pipette 210 does not drive the suction head cover 220 to move synchronously when moving. At this time, the driving mechanism 600 controls the pipette 210 to move upward, and the position of the suction head cover 220 remains unchanged. The cryopreservation tube 500 moves upward with the pipette 210, enters the suction head cover 220, and moves upward in the suction head cover 220; Figure 5 As shown, when the straw 210 moves up to the first position, the clamping protrusion 213 on the straw 210 cooperates with the clamping portion 221 on the suction head cover 220, and the straw 210 can drive the suction head cover 220 to move synchronously. At this time, the cryopreservation tube 500 can move up synchronously with the suction head cover 220, and the positional relationship between the two remains relatively unchanged. The driving mechanism 600 controls the straw 210 to continue to move up, and the straw 210 synchronously drives the suction head cover 220 to move up. Figure 6As shown, when the pipette 210 moves from the first position to the second position, the pipette 210 is synchronously driven to move upward, and the clamping assembly 400 is activated to clamp the cryopreservation tube 500. The pipette 210 moves upward, and before it moves a certain distance to reach the first position, the clamping assembly 400 will not be activated, so that the cryopreservation tube 500 can enter the appropriate position in the suction head cover 220; after the pipette 210 reaches the first position, the cryopreservation tube 500 reaches the appropriate position in the suction head cover 220, and the pipette 210 continues to move upward, which will drive the cryopreservation tube 500 and the suction head cover 220 to move upward synchronously, and the clamping assembly 400 is activated by the movement of the suction head cover 220, and the clamping assembly 400 can clamp and fix the cryopreservation tube 500 in the appropriate position.

[0051] In this embodiment, combined with Figure 3 and Figure 4 A plurality of through slots 222 are provided on the peripheral side of the pipette cover 220. The number of through slots 222 is the same as the number of clamping members 410 and they correspond one to one. Each clamping member 410 is located in a corresponding through slot 222. When the pipette cover 220 moves upward, each clamping member 410 approaches each other and enters the pipette cover 220 through the corresponding through slots 222 to clamp the cryopreservation tube 500 in the pipette cover 220. The clamping member 410 clamps the portion of the cryopreservation tube 500 located in the pipette cover 220. The clamping member 410 is located in the through slot 222, so that the movement trajectory of the clamping member 410 is stable. The through slot 222 also defines the position of the clamping member 410, so that the clamping and positioning of the cryopreservation tube 500 are more stable.

[0052] In this embodiment, the inner wall of the sleeve 300 is provided with a guide groove 310. When the straw assembly 200 moves from the initial position to the second position, the guide groove 310 is always connected with the through groove 222 to form a connected space. The clamping member 410 is a ball disposed in the connected space. The ball is a hard spherical ball and can be made of any material. As a preferred embodiment, the ball in this embodiment is a metal ball. A part of the ball is located in the guide groove 310 and a part of the ball is located in the through groove 222. When the straw 210 moves from the first position to the second position, the straw 210 sleeve rises, which will drive the ball in the through groove 222 to rise. When the ball rises, the guide groove 310 will push the ball to move into the through groove 222, so that the ball enters the through groove 222 to clamp the cryopreservation tube 500. In some embodiments, there may be a plurality of guide grooves 310, and each guide groove 310 corresponds to each through groove 222. In this embodiment, the guide groove 310 is provided with one annular inner wall of the sleeve member 300, and each through groove 222 is opposite to the guide groove 310. Providing only one guide groove 310 makes the sleeve member 300 more convenient to process, and at the same time avoids the situation that the guide groove 310 and the through groove 222 cannot be aligned due to the rotation of the straw assembly 210. A plurality of communication spaces are formed between each through groove 222 and the guide groove 310, and a ball is provided in each communication space.

[0053] like Figure 4 As shown, the guide groove 310 has: a first wall 311, a guide wall 312 and a second wall 313 arranged from bottom to top, the first wall 311 and the second wall 313 are arranged vertically, and the guide wall 312 is arranged obliquely. Before the suction tube 210 rises to the first position and when it is in the first position, the position of the suction head cover 220 and the ball remains unchanged. Figure 4 The position of the ball is shown. The ball abuts against the first wall 311, and part of the ball is located in the through groove 222. When the straw 210 moves to the second position, the ball abuts against the second wall 313. Figure 7 The position of the ball is shown, and part of the ball passes through the through slot 222 to clamp the cryopreservation tube 500; when the straw 210 moves from the first position to the second position, the Figure 4 , Figure 6 and Figure 7, the ball rolls from the first wall 311 through the guide wall 312 to abut against the second wall 313. The guide wall 312 is inclined to push the ball toward the inside of the straw assembly 200, so that the ball enters the through groove 222 to clamp the cryopreservation tube 500. During the rising process of the straw 210, after being located at the second position or before being located at the first position, the ball abuts against the vertical second wall 313 or the first wall 311 to stabilize the position of the ball, and will not continue to clamp the cryopreservation tube 500 or release the cryopreservation tube 500. After multiple balls clamp the cryopreservation tube 500, even if the vacuum of the vacuum assembly 100 fails, the ball can still stably clamp the cryopreservation tube 500. Only when the suction head cover 220 rises, the individual balls will move closer to each other under the action of the guide wall 312. The arrangement of the ball and the guide wall 312 has the advantages of simple structure, low cost, good transmission effect and no influence by the deep low temperature environment.

[0054] It is also worth noting that Figure 3 and Figure 5 As shown, the suction tube 210 and the suction head cover 220 cooperate with each other through the clamping protrusion 213 and the clamping part 221. The suction tube 210 can drive the suction head cover 220 to move upward, but the clamping part 221 and the clamping protrusion 213 cooperate in a vertical direction. When the suction tube 210 moves downward, the clamping protrusion 213 and the clamping part 221 of the suction head cover 220 will be out of cooperation, and the suction head cover 220 cannot continue to move downward. The suction head cover 220 remains in place, resulting in the situation that the clamping of the cryopreservation tube 500 cannot be unlocked. In view of this, if Figure 6 As shown, an elastic reset member 320 is further provided in the sleeve member 300 in the present embodiment. The elastic reset member 320 is provided in the sleeve member 300 and is located above the suction head cover 220. When the straw 210 is located in the first position, the top of the suction head cover 220 abuts against the elastic reset member 320. The straw 210 moves from the first position to the second position, driving the suction head cover 220 to move upward. The upwardly moved suction head cover 220 compresses the elastic reset member 320. When the straw 210 moves to the second position, the suction head cover 220 is located in the highest position, compressing the elastic reset member 320 to the shortest position. Since the straw 210 is always subjected to the force of the driving mechanism 600, the elastic reset member 320 will not be reset, and the suction head cover 220 remains in place. When the driving mechanism 600 drives the straw 210 to move downward and is ready to release the cryopreservation tube 500, the straw 210 moves downward, and the engaging protrusion 213 of the straw 210 moves downward. At this time, the resetting elastic member applies elastic force to the suction head cover 220 to move the suction head cover 220 downward. When the suction head cover 220 moves downward, the ball rolls from the second wall 313 through the guide wall 312 to abut against the first wall 311. Figure 4, wherein at least one of the upper and lower side walls of the through groove 222 is an inclined wall 2221 with a guiding function. In this embodiment, both the upper and lower side walls of the through groove 222 are inclined walls 2221. When the suction head cover 220 descends, the inclined wall 2221 of the through groove 222 will push the ball out of the through groove 222, so that the ball moves in the direction of leaving the through groove 222, and the ball always abuts against the groove wall of the guide groove 310, thereby unlocking and releasing the cryotube 500. The setting of the elastic reset member 320 can make the suction head cover 220 move downward, solving the problem that the suction pipe 210 cannot drive the suction head cover 220 to move downward, so that the cryotube 500 can be smoothly unlocked and released.

[0055] In the deep-low temperature cryotube suction device of the present embodiment, after sucking up the cryotube 500, the driving mechanism 600 automatically drives the suction tube assembly 200 to move upward, thereby driving the clamping assembly 400 to clamp the sucked cryotube 500. The clamping assembly 400 can clamp the cryotube 500 from multiple directions to ensure that the axis of the cryotube 500 is vertical, which is convenient for the placement of cryotubes; the clamping mechanism is simple and low in cost, and can stably clamp the cryotube 500.

[0056] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0057] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A cryogenic tube suction device, characterized in that: include: Vacuum components; A suction tube assembly, connected to the vacuum assembly, for sucking the product; A sleeve member, sleeved outside the straw assembly; A clamping assembly, disposed between the straw assembly and the sleeve member, the clamping assembly being connected to the straw assembly and being linked to the straw assembly; A driving mechanism, connected to the straw assembly, and used for driving the straw assembly to rise or fall in the sleeve member; When the straw assembly rises and a portion of the product enters the sleeve, the clamping assembly clamps the product; When the straw assembly descends, the clamping assembly releases the product; The clamping assembly comprises: a plurality of clamping members respectively arranged on the periphery of the straw assembly, each of the clamping members is connected to the straw assembly, and when the straw assembly rises, the clamping members are driven to approach each other; when the straw assembly descends, the clamping members are driven to move away from each other; The straw assembly comprises: A straw connected to the driving mechanism; A suction head cover is arranged in the sleeve member and sleeved outside the suction tube, and the suction head cover and the suction tube can be relatively slidably matched; The straw has a first position and a second position when it moves upward. When the straw moves upward to the first position, the straw abuts against the suction head cover in the axial direction, and the straw can drive the suction head cover to move; When the suction tube moves from the first position to the second position, the suction head cover is driven to move upward, and the suction head cover drives the clamping assembly to clamp the product; The peripheral side of the suction head cover is provided with: a plurality of through slots, the number of the through slots is the same as the number of the clamping members and corresponds to each other, and each of the clamping members is respectively arranged in a corresponding through slot, and when each of the clamping members approaches each other, each of them enters the suction head cover through the corresponding through slot to clamp the product; The inner wall of the sleeve is provided with a guide groove, the guide groove is connected with the through groove to form a connecting space, the clamping member is a ball disposed in the connecting space, and when the suction head cover rises, the groove wall of the guide groove pushes the clamping member toward the inside of the suction head cover; The sleeve member is provided with an elastic reset member, and the elastic reset member is arranged above the suction head cover. When the suction tube moves from the first position to the second position, the suction head cover moves upward and compresses the elastic reset member.

2. The suction device according to claim 1, characterized in that: The guide groove comprises: a first wall, a guide wall and a second wall arranged from bottom to top; when the ball abuts against the first wall, part of it is located in the through groove; when the ball abuts against the second wall, part of it enters the straw assembly through the through groove; when the suction head cover rises, the ball rolls from the first wall through the guide wall to abut against the second wall, and the guide wall pushes the ball toward the inside of the straw assembly.

3. The suction device according to claim 2, characterized in that: The suction tube comprises: a connecting portion connected to the driving mechanism, a suction head portion, and a buffer portion connected between the connecting portion and the suction head portion, and the suction head sleeve is sleeved on the suction head portion.

4. The suction device according to claim 3, characterized in that: The side wall of the through groove is an inclined wall, and the inclined wall is used to push the ball into the guide groove.

5. The suction device according to claim 1, characterized in that: The driving mechanism comprises: a driving member, and a transmission assembly connected between the driving member and the straw assembly, wherein the transmission assembly is used to drive the straw assembly to rise or fall under the drive of the driving member; The suction device further comprises: a motor cover, and the driving mechanism and the heating module are both arranged in the motor cover.

Citation Information

Patent Citations

  • Portable sucking pipe device

    CN207807778U

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    CN211009403U

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    CN213995979U

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