Detector, sample testing method
By designing a fully automatic sample detector that includes a flow pump set, a detection unit, a transmission mechanism and a controller, the problems of low sample detection efficiency and device contamination in the existing technology are solved, and efficient and accurate automated detection is achieved.
Patent Information
- Application Number
- CN202011109439.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-10-16
- Publication Date
- 2025-01-21
- Estimated Expiration
- 2040-10-16
AI Technical Summary
Existing sample detectors require complex manual processing, low detection efficiency, and the detection device does not fully consider flow path cleaning and protection, which can easily lead to contamination and bacterial growth.
A detector including a flow pump unit, a detection unit, a transmission mechanism and a controller is designed. The controller controls the working status of each component to achieve fully automatic and rapid detection. The detector is equipped with a sample pool, a adding head, a syringe pump, a cartridge and a sample detection chamber, and realizes the cleaning of the sample pool and the automatic transmission of the detection card through a three-way reversing valve and a transmission mechanism.
It achieves full automation of sample detection, improves detection efficiency and accuracy, reduces manual operations, and avoids contamination of the detection device and bacterial growth.
Smart Images

Figure CN112114161B_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the field of sample detectors, and in particular relates to a detector and a sample detection method. Background Art
[0002] Sample detectors are widely used in water ecological environment monitoring, food testing, drug testing and other fields, but existing detectors generally still require complex manual processing, and samples can only be tested in the circulation link. The sample testing process is complicated, the testing cycle is long, and the testing efficiency is low; and the existing sample detection device does not fully consider the flow path cleaning and protection issues, which easily leads to detector contamination, affects the accuracy of sample detection, and cannot prevent bacteria from growing in the pipeline when the detection instrument is idle for a long time. Therefore, it is necessary to consider improving the structure of the existing sample detection device to achieve automated sample detection. Summary of the invention
[0003] In view of the deficiencies of the above-mentioned existing sample detectors, the present invention provides a detector capable of realizing automatic sample detection, and provides a sample detection method.
[0004] In order to achieve the above-mentioned object, the present invention provides a detector, comprising: a flow pump group, a base, a detection unit, a transmission mechanism, and a controller, wherein the detection unit and the transmission mechanism are placed on the base;
[0005] The detection unit includes at least one sample pool, a sample adding head, a syringe pump, a card compartment, and a sample detection chamber;
[0006] The sample pool is connected to the flow pump group and the injection pump at the same time, the injection pump is connected to the sample adding head through the first sampling tube, and the sample adding head is suspended above the sample detection chamber;
[0007] The card compartment stores a test card for sample testing;
[0008] The transmission mechanism includes a stepper motor and a rack, the output end of the stepper motor is fixedly connected to the rack, the rack is connected to the sample detection chamber through the bottom of the card chamber, and the detection card stored in the card chamber can be linked to the rack to the sample detection chamber for sample detection;
[0009] The controller controls and connects the injection pump, the stepping motor, the reversing valve, the sample adding head and the flow pump group respectively.
[0010] Preferably, the sample pool is connected to the injection pump via a first pipeline and a second sampling tube in sequence;
[0011] The first pipeline is connected to the sample pool, and the second sampling tube is connected to the injection pump;
[0012] The first pipeline is connected to the second sampling tube through a reversing valve.
[0013] Preferably, the detection unit is further provided with a waste discharge pipeline, the reversing valve is configured as a three-way reversing valve, and the first pipeline is connected to the sample pool, the injection pump, and the waste discharge pipeline through the three-way reversing valve.
[0014] Preferably, the reversing valve is a solenoid valve.
[0015] Preferably, the sample detection chamber is provided with a plurality of card slots for placing detection cards.
[0016] Preferably, a first crossbeam is further provided on the base, a camera is mounted on the first crossbeam, and the camera is electrically connected to the controller.
[0017] Preferably, a second crossbeam is provided on the base, and the sample adding head is sleeved on the second crossbeam via a slider and can move horizontally along the second crossbeam along with the slider.
[0018] Preferably, the flow pump group includes at least one filter head and a flow pump, the filter head is connected to the flow pump through a pipeline, and the flow pump is connected to the sample pool through a pipeline.
[0019] The present invention also provides a sample detection method, using the detector, comprising:
[0020] Before the sample is tested, the stepper motor is started and the test card stored in the card bin is transferred to the sample testing room through the rack;
[0021] Sample detection: The controller controls the flow pump to stop working, the reversing valve opens to the second sampling tube, and connects to the injection pump. The injection pump absorbs the sample to be tested at full scale, and a certain amount of the sample to be tested is added to the sampling head. The sampling head moves to add the sample to be tested to the test card in the sample detection room one by one for sample detection. The camera synchronously collects the sample detection information and transmits it to the controller for detection result analysis.
[0022] Preferably, before the sample test, it is necessary to flush the sample pool, sample and mix, and flush the injection pump in sequence; after the sample test is completed, it is necessary to empty the waste liquid; specifically:
[0023] Flushing the sample pool: The controller controls the flow pump to work, the reversing valve is opened to the waste pipe, the injection pump does not work, and the sample pool is flushed;
[0024] Sampling and mixing: The controller controls the flow pump to work, the reversing valve opens to the second sampling tube, connects to the injection pump, the injection pump does not work, and sampling and mixing are performed;
[0025] Flushing the syringe pump: The controller controls the flow pump to stop working, the reversing valve opens to the second sampling tube, and connects the syringe pump. After the syringe pump absorbs the sample at full scale, it is discharged through the sampling head to flush the syringe pump;
[0026] Emptying the waste liquid: After the sampling and testing of the sample to be tested is completed, the controller controls the flow pump to stop working, and the reversing valve is opened to the waste liquid pipeline, and the residual test samples in the sample pool and the injection pump are emptied through the waste liquid pipeline and the sampling head.
[0027] Compared with the prior art, the advantages and positive effects of the present invention are:
[0028] The present invention provides a detector with a simple structural design and capable of realizing full-automatic rapid detection. By setting a flow pump group, a detection unit, a transmission mechanism, and a controller, the controller controls the working state of the flow pump group, the detection unit, and the transmission mechanism, and realizes full-automatic rapid detection of samples by the detector, thereby improving detection efficiency. At the same time, the sample pool, the injection pump, and the waste discharge pipeline are connected through a three-way reversing valve, and the conduction direction of the reversing valve can be controlled to control the sample pool to be connected to the injection pump or the waste discharge pipeline, and operations such as sample pool cleaning or liquid mixing can be performed. At the same time, a card warehouse and a sample detection chamber are set, and a detection card for sample detection is stored in the card warehouse, and a plurality of card slots for placing the detection card are arranged in the sample detection chamber, and a rack is connected to the sample detection chamber through the bottom of the card warehouse, so that after the stepper motor is started, the detection card stored in the card warehouse can be linked with the rack to the sample detection chamber, and multiple detection cards in the sample detection chamber can be added to the sample detection chamber synchronously for detection, so as to improve the detection efficiency, so as to facilitate automatic and rapid sample detection. The detector of the present invention can be used for drug testing, food testing, water quality testing and the like. The test results can be uploaded to the data platform synchronously. The testing process is fully automated without the need for additional manual input. Only the test card in the card compartment needs to be replaced according to actual needs. The structure is simple and the operation is convenient. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] Figure 1 It is the overall structure diagram of the detector of the present invention;
[0030] Figure 2 This is a top view of the structure of the detector;
[0031] Figure 3 This is the structural diagram of the flow pump group of the detector;
[0032] Among them: flow pump group 1, filter head 11, flow pump 12, base 2, first beam 21, second beam 22, detection unit 3, sample pool 31, sample adding head 32, injection pump 33, first sampling tube 331, first pipeline 332, second sampling tube 333, card warehouse 34, sample detection chamber 35, card slot 351, reversing valve 36, waste discharge pipeline 37, camera 38, transmission mechanism 4, stepping motor 41, rack 42. DETAILED DESCRIPTION
[0033] In order to make those skilled in the art better understand the scheme of the present invention, the technical scheme in the embodiment of the present invention will be clearly described below in conjunction with the drawings in the embodiment of the present invention. The term "comprising" in the specification and claims of the present invention and the above-mentioned drawings and any variation thereof are intended to cover non-exclusive inclusions. For example, a process, method or system, product or device comprising a series of steps or units is not limited to the listed steps or units, but optionally also includes steps or units that are not listed, or optionally also includes other steps or units inherent to these processes, methods, products or devices. In addition, the terms "first", "second" and "third" etc. are used to distinguish different objects, rather than to describe a specific order.
[0034] refer to Figure 1-Figure 3 As shown, the present invention provides a detector, comprising: a flow pump group 1, a base 2, a detection unit 3, a transmission mechanism 4, and a controller (not shown in the figure), wherein the detection unit 3 and the transmission mechanism 4 are fixed on the base 2.
[0035] Further references Figure 1 , Figure 2 As shown, the detection unit 3 in the present invention includes at least one sample pool 31, a sample adding head 32, a syringe pump 33, a card compartment 34, and a sample detection chamber 35. The sample pool 31 is connected to the flow pump group 1 and the syringe pump 33 at the same time. The syringe pump 33 is connected to the sample adding head 32 through the first sampling tube 331, and the sample adding head 32 is suspended above the sample detection chamber 35. The sample pool 31 is connected to the syringe pump 33 through the first pipeline 332 and the second sampling tube 333 in sequence. The first pipeline 332 is connected to the sample pool 31, the second sampling tube 333 is connected to the syringe pump 33, and the first pipeline 332 is connected to the second sampling tube 333 through the reversing valve 36. In this embodiment, in order to facilitate the flushing of the sample pool, a waste pipe 37 is further provided, and the waste pipe 37 forms a three-way connection with the first pipe 332 and the second sampling pipe 333. That is, in actual design, the reversing valve 36 can be set as a three-way solenoid valve, and the first pipe 333 is connected to the sample pool 31, the injection pump 33, and the waste pipe 37 through the three-way solenoid valve.
[0036] Further references Figure 1 , Figure 2As shown, the conveying mechanism 4 includes a stepper motor 41 and a rack 42. The output end of the stepper motor 41 is fixedly connected to the rack 42. The rack 42 is connected to the sample detection chamber 35 through the bottom of the card chamber 34. In this embodiment, the card chamber 34 stores detection cards for sample detection. The sample detection chamber 35 is provided with a plurality of card slots 351 for placing detection cards. After the stepper motor 41 is started, the detection cards stored in the card chamber 34 can be linked with the rack 42 to the card slots 351 of the sample detection chamber 35, so as to automatically and quickly perform sample detection.
[0037] Further references Figure 2 In this embodiment, the base 2 is also provided with a first crossbeam 21, and a camera 38 is installed on the first crossbeam 21, and the camera 38 can take real-time pictures of the sample detection status. The base 2 is provided with a second crossbeam 22, and the sample adding head 32 is sleeved on the second crossbeam 22 through a slider, and can move horizontally along the second crossbeam 22 with the slider, and the sample detection chamber 35 is placed under the second crossbeam 22. By controlling the movement of the sample adding head 32 along the second crossbeam 22, multiple detection cards in the sample detection chamber 35 can be added with samples for synchronous detection, so as to improve the detection efficiency.
[0038] Further references Figure 3 As shown, in this embodiment, the flow pump group 1 includes at least one filter head 11 and a flow pump 12. The filter head 11 is connected to the flow pump 12 through a pipeline, and the flow pump 12 is connected to the sample pool 31 through a pipeline. The flow pump group 1 can be used to control the injection of a certain amount of sample into the sample pool 31.
[0039] In this embodiment, in order to facilitate the automatic detection control of the detector, a controller is further provided, and a control program is stored in the controller, which controls the controller to connect the injection pump 33, the stepping motor 41, the reversing valve 36, the sample adding head 32, the camera 38, the flow pump group 1, etc. The controller controls the working state of the flow pump group 1 to inject liquid into the sample pool 31; by controlling the conduction direction of the reversing valve 36, it can realize the control of the sample pool 31 to connect the injection pump 33 or the waste discharge pipeline 37, and perform operations such as cleaning or mixing the sample pool; at the same time, the injection pump 33 can be controlled to add samples to the sample adding head 32, and the movement of the sample adding head 32 along the second crossbeam 22 can be controlled to add samples to multiple detection cards in the sample detection chamber 35 for synchronous detection, so as to improve the detection efficiency. At the same time, the controller can control the asynchronous motor 41 to work, and the detection card stored in the card compartment 34 can be linked to the card slot 351 of the sample detection chamber 35 with the rack 42, so as to automatically and quickly perform sample detection. At the same time, the controller communicates with the camera 38 and can receive the detection information collected by the camera 38 in real time to analyze the detection results and monitor the detection process.
[0040] In summary, the detector of the present invention is provided with a flow pump group 1, a detection unit 3, a transmission mechanism 4, and a controller. The working states of the flow pump group 1, the detection unit 3, and the transmission mechanism 4 are controlled by the controller to realize full-automatic and rapid detection of samples by the detector. It does not require complicated manual processing procedures and can monitor the detection process in real time, thereby improving the detection efficiency and the accuracy of the detection results.
[0041] The detector of the present invention has a simple structure design. The sample pool 31, the injection pump 33, and the waste discharge pipeline 37 are connected through a three-way reversing valve. The sample pool 31 can be controlled to connect to the injection pump 33 or the waste discharge pipeline 37 by controlling the conduction direction of the reversing valve 36, so as to perform operations such as cleaning the sample pool or mixing liquids. At the same time, a card compartment 34 and a sample detection chamber 35 are provided. The card compartment stores detection cards for sample detection. The sample detection chamber 35 is provided with a plurality of card slots 351 for placing detection cards. The rack 42 is connected to the sample detection chamber 35 through the bottom of the card compartment 34. After the stepper motor 41 is started, the detection cards stored in the card compartment 34 can be linked to the card slots 351 of the sample detection chamber 35 with the rack 42. The multiple detection cards in the sample detection chamber 35 can be added to the samples synchronously for detection, so as to improve the detection efficiency and facilitate automatic and rapid sample detection. The detector of the present invention can be used for drug testing, food testing, water quality testing and the like. The test results can be uploaded to the data platform synchronously. The testing process is fully automated without the need for additional manual input. Only the test card in the card compartment needs to be replaced according to actual needs.
[0042] Based on the above-mentioned detector, the present invention also provides a corresponding sample detection method. Before the sample is tested, it is necessary to store the test card for the sample test in the card compartment according to the actual test items, so that when the stepper motor is started, the test card stored in the card compartment can be transferred to the sample detection chamber through the rack. At the same time, before the formal test of the sample, it is also necessary to flush the sample pool and the injection pump in sequence to avoid sample contamination; at the same time, after the sample test is completed, it is also necessary to empty the sample pool and the injection pump, etc., to avoid corrosion contamination of the sample pool and the injection pump, bacterial growth, etc. when the detector is idle for a long time. The specific detection process mainly includes the following:
[0043] Flushing the sample pool: The controller controls the flow pump to work, the reversing valve is opened to the waste pipe, the injection pump does not work, and the sample pool is flushed.
[0044] Sampling and mixing: The controller controls the flow pump to work, the reversing valve opens to the second sampling tube, connects to the injection pump, the injection pump does not work, and sampling and mixing are performed.
[0045] Flushing the syringe pump: The controller controls the flow pump to stop working, and the reversing valve opens to the second sampling tube, connecting the syringe pump. After the syringe pump absorbs the sample at full scale, it is discharged through the sampling head to flush the syringe pump.
[0046] Sample detection: The controller controls the flow pump to stop working, the reversing valve opens to the second sampling tube, and connects to the injection pump. The injection pump absorbs the sample to be tested at full scale, and a certain amount of the sample to be tested is added to the sampling head. The sampling head moves to add the sample to be tested to the test card in the sample detection room one by one for sample detection. The camera synchronously collects the sample detection information and transmits it to the controller for detection result analysis.
[0047] Emptying the waste liquid: After the sampling and testing of the sample to be tested is completed, the controller controls the flow pump to stop working, and the reversing valve is opened to the waste liquid pipeline, and the residual test samples in the sample pool and the injection pump are emptied through the waste liquid pipeline and the sampling head.
[0048] The above description is only a preferred embodiment of the present invention and does not limit the present invention in other forms. Any technician familiar with the profession may use the technical content disclosed above to change or modify it into an equivalent embodiment with equivalent changes and apply it to other fields. However, any simple modification, equivalent change and modification made to the above embodiment based on the technical essence of the present invention without departing from the content of the technical solution of the present invention still falls within the protection scope of the technical solution of the present invention.
Claims
1. A detector, characterized in that: include: A flow pump group, a base, a detection unit, a transmission mechanism, and a controller, wherein the detection unit and the transmission mechanism are placed on the base; The detection unit includes at least one sample pool, a sample adding head, a syringe pump, a card compartment, and a sample detection chamber; The sample pool is connected to the flow pump group and the injection pump at the same time, the injection pump is connected to the sample adding head through the first sampling tube, and the sample adding head is suspended above the sample detection chamber; The sample pool is connected to the injection pump through a first pipeline and a second sampling tube in sequence, the first pipeline is connected to the sample pool, the second sampling tube is connected to the injection pump, and the first pipeline is connected to the second sampling tube through a reversing valve; Wherein, the detection unit is provided with a waste discharge pipeline, the reversing valve is provided as a three-way reversing valve, and the first pipeline is connected to the sample pool, the injection pump, and the waste discharge pipeline through the three-way reversing valve; The card compartment stores a test card for sample testing; The transmission mechanism includes a stepper motor and a rack, the output end of the stepper motor is fixedly connected to the rack, the rack is connected to the sample detection chamber through the bottom of the card chamber, and the detection card stored in the card chamber can be linked to the rack to the sample detection chamber for sample detection; The detection process includes: flushing the sample pool: the controller controls the flow pump to work, the reversing valve opens to the waste pipe, the injection pump does not work, and the sample pool is flushed; sampling and mixing: the controller controls the flow pump to work, the reversing valve opens to the second sampling tube, connects the injection pump, the injection pump does not work, and sampling and mixing are performed; flushing the injection pump: the controller controls the flow pump to not work, the reversing valve opens to the second sampling tube, connects the injection pump, and after the injection pump absorbs the sample at full scale, it is discharged through the sampling head to flush the injection pump; sample detection: the controller controls the flow pump to not work , the reversing valve opens to the second sampling tube, connected to the injection pump, the injection pump draws the sample to be tested at full scale, adds a certain amount of the sample to be tested to the sampling head, the sampling head moves to add the sample to be tested to the test card in the sample detection room one by one, and performs sample detection. The camera synchronously collects the sample detection information and transmits it to the controller for analysis of the detection results; emptying the waste liquid: after the sampling and detection of the sample to be tested is completed, the controller controls the flow pump not to work, and the reversing valve opens to the waste liquid pipeline, and the residual detection samples in the sample pool and the injection pump are emptied through the waste liquid pipeline and the sampling head respectively.
2. The detector according to claim 1, characterized in that: The reversing valve is a solenoid valve.
3. The detector according to claim 1, characterized in that: The sample detection chamber is provided with a plurality of card slots for placing detection cards.
4. The detector according to claim 1, characterized in that: A first crossbeam is also provided on the base, a camera is mounted on the first crossbeam, and the camera is electrically connected to the controller.
5. The detector according to any one of claims 1 to 4, characterized in that: A second crossbeam is arranged on the base, and the sample adding head is sleeved on the second crossbeam through a sliding block and can move horizontally along the second crossbeam along with the sliding block.
6. The detector according to any one of claims 1 to 4, characterized in that: The flow pump group includes at least one filter head and a flow pump. The filter head is connected to the flow pump through a pipeline, and the flow pump is connected to the sample pool through a pipeline.
7. A sample detection method, using the detector according to any one of claims 1 to 6, characterized in that: include: Before the sample is tested, the stepper motor is started and the test card stored in the card bin is transferred to the sample testing room through the rack; Sample detection: The controller controls the flow pump to stop working, the reversing valve opens to the second sampling tube, connects to the syringe pump, the syringe pump absorbs the sample to be tested at full scale, adds a certain amount of the sample to be tested to the sampling head, the sampling head moves to add the sample to be tested to the test card in the sample detection room one by one, and performs sample detection. The camera synchronously collects the sample detection information and transmits it to the controller for analysis of the detection results; Before the sample is tested, it is necessary to flush the sample pool, mix the sample, and flush the injection pump in sequence; after the sample is tested, the waste liquid needs to be drained; specifically: Flushing the sample pool: The controller controls the flow pump to work, the reversing valve is opened to the waste pipe, the injection pump does not work, and the sample pool is flushed; Sampling and mixing: The controller controls the flow pump to work, the reversing valve opens to the second sampling tube, connects to the injection pump, the injection pump does not work, and sampling and mixing are performed; Flushing the syringe pump: The controller controls the flow pump to stop working, the reversing valve opens to the second sampling tube, and connects to the syringe pump. After the syringe pump absorbs the sample at full scale, it is discharged through the sampling head to flush the syringe pump; Emptying the waste liquid: After the sampling and testing of the sample to be tested is completed, the controller controls the flow pump to stop working, and the reversing valve is opened to the waste liquid pipeline, and the residual test samples in the sample pool and the injection pump are emptied through the waste liquid pipeline and the sampling head.
Citation Information
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