Sample loading arm operation device and sample loading and cleaning method thereof

Abstract

The present invention provides a loading arm operation device, comprising a dyeing and washing cantilever, a cleaning needle, a reagent needle, a first motor, a second motor and a rotating shaft; the cleaning needle and the reagent needle are arranged on the dyeing and washing cantilever, and the dyeing and washing cantilever is detachably connected to the rotating shaft; the first motor can drive the rotating shaft to move in the X-axis direction, and the dyeing and washing cantilever rotates to a position directly above the sedimentation bin; when the loading arm is in a first working state, the second motor drives the dyeing and washing cantilever downward, and the cleaning needle and the reagent needle move downward to a corresponding sedimentation cup; when the loading arm is in a second working state, the second motor drives the dyeing and washing cantilever upward, and the sedimentation disc synchronously rotates the sedimentation cup on which the reagent needle has been loaded to a position directly above the cleaning needle. The present invention can realize simultaneous loading and cleaning, save a lot of time in the inspection process, and improve the efficiency of film output.

Description

Technical Field

[0001] The present invention relates to the field of biological testing technology, and in particular to a sample loading arm operation device and a sample loading and cleaning method thereof. Background Art

[0002] Medical testing technology equipment plays an important role in clinical diagnosis. After sample collection, the test usually includes the step of adding samples. In existing sample adding equipment, a sample adding arm is usually used to add samples to the reaction plate on the sample platform, and only one reagent needle can perform the sample adding operation, which is time-consuming and has low test efficiency.

[0003] After searching, the patent document CN210427602U discloses a fully automatic gas-liquid replacement sampler, including a base, a tip rack assembly and a sample rack assembly fixedly connected to the base are arranged on the top of the base, a first motor on the base drives the sample loading arm device to slide along the first linear guide rail, a second motor in the sample loading arm device drives the sample loading channel device to slide along the second linear guide rail, and an automatic syringe and an automatic needle removal device are arranged on the sample loading channel device. The disadvantage of this prior art is that the sample loading and cleaning cannot be performed at the same time, the film output efficiency cannot be improved, and the results cannot be efficiently and timely produced when there are a large number of samples to be tested. Summary of the invention

[0004] In view of the defects in the prior art, an object of the present invention is to provide a sample loading and running device and a sample loading and cleaning method thereof.

[0005] A sample loading operation device provided by the present invention comprises: a dyeing and washing cantilever, a cleaning needle, a reagent needle, a first motor, a second motor and a rotating shaft; wherein the cleaning needle and the reagent needle are arranged on the dyeing and washing cantilever, and the dyeing and washing cantilever is detachably connected to the rotating shaft; the first motor can drive the rotating shaft to move in the X-axis direction, and the dyeing and washing cantilever rotates to a position just above the sedimentation bin;

[0006] When the sample loading arm is in the first working state, the second motor drives the dyeing and washing cantilever downward, and the cleaning needle and the reagent needle move downward to the corresponding sedimentation cup;

[0007] When the sample adding arm is in the second working state, the second motor drives the dyeing and washing cantilever upward, and the sedimentation plate synchronously rotates the sedimentation cup on which the reagent needle has undergone the sample adding operation to a position just above the cleaning needle.

[0008] Preferably, the dyeing and washing cantilever is a "T"-shaped structure, and the side of the horizontal arm of the dyeing and washing cantilever away from the vertical arm of the dyeing and washing cantilever is in an arc shape.

[0009] Preferably, the rotating shaft comprises a coupling and a spline shaft, and the coupling is connected between the dyeing and washing cantilever and the spline shaft.

[0010] Preferably, a belt and a driven pulley are provided on the first motor, and the rotating shaft rotates in the X-axis direction by the transmission of the belt and the driven pulley.

[0011] Preferably, a pulley and a belt are provided on the second motor, and the pulley and the belt move in coordination so that the rotating shaft performs a lifting movement in the Z-axis direction.

[0012] Preferably, it also includes a guide shaft and a Z-axis moving plate, the spline shafts on the guide shaft and the rotating shaft are fixed on the Z-axis moving plate, and the Z-axis moving plate moves in the Y-axis direction on the guide shaft.

[0013] Preferably, it also includes an in-position sensor, which is arranged on the Z-axis moving plate, and the moving position of the Z-axis moving plate is determined by using the in-position sensor.

[0014] Preferably, it also includes an inclined plate, which is connected to the extension of the dyeing and washing cantilever, and the bottom of the inclined plate is vertically connected to the coupling of the rotating shaft.

[0015] Preferably, a buffer device is provided on the cleaning needle, and the buffer device includes a buffer plate and a spring, one end of the buffer plate is connected to the cleaning needle, and the other end of the buffer plate is connected to the spring.

[0016] According to a method for sample loading and cleaning provided by the present invention, the sample loading and cleaning is performed using the above-mentioned sample loading arm operation device.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] 1. The sample loading and cleaning can be carried out simultaneously by using the sample loading arm operation device, which saves a lot of time in the inspection process and improves the efficiency of film output.

[0019] 2. The first motor and the second motor are used to drive the sample loading arm to rotate left and right and up and down so that the sample loading arm can load samples and clean in the sedimentation chamber at the same time.

[0020] 3. By arranging a buffer device on the cleaning needle and the reagent needle, a buffering effect can be achieved and inertia can be used to achieve a rebound effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Other features, objects and advantages of the present invention will become more apparent from the detailed description of non-limiting embodiments made with reference to the following drawings:

[0022] Figure 1 It is a schematic diagram of the overall structure of the sample loading arm operation device.

[0023] In the figure:

[0024] DETAILED DESCRIPTION

[0025] The present invention is described in detail below in conjunction with specific embodiments. The following embodiments will help those skilled in the art to further understand the present invention, but are not intended to limit the present invention in any form. It should be noted that, for those of ordinary skill in the art, several changes and improvements can also be made without departing from the concept of the present invention. These all belong to the protection scope of the present invention.

[0026] The present invention provides a sample loading arm operation device, comprising: a dyeing and washing cantilever 31, a cleaning needle 3, a reagent needle 33, a rotating shaft, a first motor 36, a second motor 37, an in-position sensor 38, a Z-axis moving plate 39, a buffer device 310, an inclined plate and a guide shaft, the cleaning needle 32 and the reagent needle 33 are arranged on the dyeing and washing cantilever 31, and the dyeing and washing cantilever 31 is detachably connected to the rotating shaft; wherein the rotating shaft comprises a coupling 34 and a spline shaft 35, and the coupling 34 is connected between the dyeing and washing cantilever 31 and the spline shaft 35. The coupling 34 refers to a device that connects two shafts or a shaft and a rotating part, rotates together during the process of transmitting motion and power, and does not disengage under normal circumstances. Sometimes it is also used as a safety device to prevent the connected parts from being subjected to excessive loads, and plays a role in overload protection.

[0027] Specifically, the first motor 36 is provided with a belt and a driven pulley, and the rotating shaft rotates in the X-axis direction by the transmission of the belt and the driven pulley; the second motor 37 is provided with a pulley and a belt, and the rotating shaft performs a lifting movement in the Z-axis direction by the coordinated movement of the pulley and the belt.

[0028] Furthermore, the in-position sensor 38 is set on the Z-axis moving plate 39, and the in-position sensor 38 is used to determine the moving position of the Z-axis moving plate 39; the guide shaft and the spline shaft 35 are both fixed on the Z-axis moving plate, and the Z-axis moving plate 39 moves in the Y-axis direction on the guide shaft.

[0029] Furthermore, the inclined plate is connected to the extension of the dyeing and washing cantilever 31, the bottom of the inclined plate is vertically connected to the coupling (34) of the rotating shaft, and the small hole on the inclined plate is used to pass the pipe for the inlet and outlet of the liquid connecting the reagent needle 33 and the cleaning needle 32. The cleaning needle 32 is provided with a buffer device 310, including a buffer plate and a spring, one end of the buffer plate is connected to the cleaning needle 32, and the other end of the buffer plate is connected to the spring.

[0030] Furthermore, the dyeing and washing cantilever 31 is a “T”-shaped structure, and the horizontal arm of the dyeing and washing cantilever 31 is in an arc shape at a side away from the vertical arm of the dyeing and washing cantilever.

[0031] Sample addition and cleaning method:

[0032] Step 1: Push the slide into the sedimentation bin fixed on the sedimentation tray;

[0033] Step 2: The sedimentation plate rotates the glass slide to the sample loading position, and the sample loading arm uses the second motor to perform vertical movement to achieve the sample loading action;

[0034] Step 3: Use the three grooves under the second cleaning plate (the middle groove is used to blow air to make the liquid roll, and the grooves on both sides are used to drain the reagent). The large plate rotates into the cleaning needle position and the cleaning needle spits out the cleaning agent. Use the three grooves under the first cleaning plate to perform the same spewing and suction action in the previous step to clean the sedimentation cup.

[0035] The present invention Preferred Example , for further explanation.

[0036] According to the above basic embodiment, the side of the horizontal arm of the dyeing and washing cantilever 31 away from the vertical arm of the dyeing and washing cantilever is in an arc shape, and the arc thereof is kept the same as the arc of the sedimentation plate, so that the operation coordination of the sample adding arm is more precise.

[0037] The above describes the specific embodiments of the present invention. It should be understood that the present invention is not limited to the above specific embodiments, and those skilled in the art can make various changes or modifications within the scope of the claims, which does not affect the essence of the present invention. In the absence of conflict, the embodiments of the present application and the features in the embodiments can be combined with each other arbitrarily.

Claims

1. A sample loading arm operation device, characterized in that: include: A dyeing and washing cantilever (31), a cleaning needle (32), a reagent needle (33), a first motor (36), a second motor (37) and a rotating shaft; The cleaning needle (32) and the reagent needle (33) are arranged on the dyeing and washing cantilever (31), and the dyeing and washing cantilever (31) is detachably connected to the rotating shaft; The first motor (36) can drive the rotating shaft to move in the X-axis direction, and the dyeing and washing cantilever (31) rotates to a position just above the sedimentation bin; When the sample loading arm is in the first working state, the second motor drives the dyeing and washing cantilever (31) downward, and the cleaning needle (32) and the reagent needle (33) move downward into the corresponding sedimentation cup; When the sample loading arm is in the second working state, the second motor drives the dyeing and washing cantilever (31) upward, and the sedimentation plate synchronously rotates the sedimentation cup on which the reagent needle (33) has been loaded with samples to a position directly above the cleaning needle (32); The first motor (36) is provided with a belt and a driven pulley, and the rotating shaft rotates in the X-axis direction by the transmission of the belt and the driven pulley; The second motor (37) is provided with a pulley and a belt, and the rotating shaft performs a lifting movement in the Z-axis direction by using the coordinated movement of the pulley and the belt; The cleaning needle (32) is provided with a buffer device (310), and the buffer device (310) comprises a buffer plate and a spring, one end of the buffer plate is connected to the cleaning needle (32), and the other end of the buffer plate is connected to the spring.

2. The sample loading arm operation device according to claim 1, characterized in that: The dyeing and washing cantilever (31) is a quasi-T-shaped structure, and the side of the horizontal arm of the dyeing and washing cantilever (31) away from the vertical arm of the dyeing and washing cantilever (31) is in an arc shape.

3. The sample loading arm operation device according to claim 1, characterized in that: The rotating shaft comprises a coupling (34) and a spline shaft (35), and the coupling (34) is connected between the dyeing and washing boom (31) and the spline shaft (35).

4. The sample loading arm operation device according to claim 1, characterized in that: It also includes a guide shaft and a Z-axis moving plate (39), wherein the spline shaft (35) on the guide shaft and the rotating shaft are both fixed on the Z-axis moving plate (39), and the Z-axis moving plate (39) moves in the Y-axis direction on the guide shaft.

5. The sample loading arm operation device according to claim 4, characterized in that: It also includes an in-position sensor (38), which is arranged on the Z-axis moving plate (39). The in-position sensor (38) is used to determine the moving position of the Z-axis moving plate (39).

6. The sample loading arm operation device according to claim 1, characterized in that: It also comprises an inclined plate, which is connected to the extension of the dyeing and washing cantilever (31), and the bottom of the inclined plate is vertically connected to the coupling (34) of the rotating shaft.

7. A method for sample addition and cleaning, characterized in that: The sample loading and cleaning is performed using the sample loading arm operation device described in any one of claims 1 to 6.

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