A nitrogen filling device
By designing a nitrogen filling equipment including vacuuming, liquid filling, nitrogen filling and melting treatment, the problem that the sealing of the medicine bag cannot be guaranteed during transportation between different production links and the nitrogen filling process is difficult to carry out continuously with other processing processes, and the continuousization of the medicine bag packaging process and the improvement of production efficiency are achieved.
Patent Information
- Application Number
- CN202011079546.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-10-10
- Publication Date
- 2025-04-18
- Estimated Expiration
- 2040-10-10
AI Technical Summary
In the pharmaceutical field, in the hard tube soft bag packaging process, drugs need to be protected with nitrogen during the packaging process. However, the existing process causes the sealing of the medicine bag to be unable to be guaranteed when transported between different production links, and the residual oxygen content is too high, which affects the nitrogen filling process, and it is difficult to carry out continuously with other processing processes, affecting production efficiency.
A nitrogen filling equipment is designed, including a vacuum device, a liquid filling device, a nitrogen filling device, a melting device and a transport device. By continuously vacuuming, liquid filling, nitrogen filling and melting treatment, the medicine bag is filled. The nitrogen replenishment and nitrogen replenishment devices provided in the nitrogen filling device and the melting device respectively replenish nitrogen to the medicine bag at different production links to ensure that the residual oxygen content of the medicine bag is low.
On the premise of ensuring a low residual oxygen level, improve production efficiency, realize the continuousization of the medicine bag packaging process, shorten the production cycle, and improve production efficiency.
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Figure CN112158384B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of pharmaceuticals, and in particular to nitrogen filling equipment. Background Art
[0002] In the pharmaceutical field, some drugs are restricted by the occasions of use and must be packaged in hard tube soft bags. These drugs are affected by their own characteristics and need to be protected by nitrogen during packaging. The special structure of the soft bag and the increase of nitrogen filling process make this soft bag packaging process a technical problem. Hard tube soft bags are also soft bags with hard tube openings. The existing production process of this soft bag with a special structure usually includes multiple processes such as cleaning, filling and packaging. Different processes are usually carried out in different production links. In this way, the soft bag needs to be transported between different production links, so that the sealing of the soft bag during the packaging process cannot be guaranteed. In addition, the special structure leads to excessive residual oxygen in the soft bag, and nitrogen filling treatment cannot be carried out. In addition, although it is still feasible to fill the soft bag with nitrogen alone, this packaging work makes it difficult to carry out the nitrogen filling process continuously with other processing technologies, affecting production efficiency.
[0003] Therefore, how to improve production efficiency while ensuring a low residual oxygen content is a technical problem that technicians in this field need to solve. Summary of the invention
[0004] In view of this, the object of the present invention is to provide a nitrogen filling device, in which the medicine bag is transported to a sealing device via a transport device after being subjected to vacuum evacuation, liquid filling and nitrogen filling treatment in sequence, and then the sealing device performs the sealing treatment. The nitrogen replenishing device provided at the nitrogen filling device and the nitrogen adding device provided at the sealing device can both replenish nitrogen to the medicine bag to ensure that the medicine bag has a lower residual oxygen content, thereby improving production efficiency under the premise of ensuring a lower residual oxygen content.
[0005] The specific plan is as follows:
[0006] The nitrogen filling equipment provided by the present invention comprises:
[0007] A vacuum device for extracting air from medicine bags;
[0008] A liquid filling device for filling the vacuumed medicine bag with liquid;
[0009] A nitrogen filling device for filling nitrogen into the medicine bag after liquid filling; the nitrogen filling device is provided with a nitrogen replenishing device for replenishing nitrogen at the transition connection between the nitrogen filling device and the medicine bag;
[0010] A sealing device for sealing the medicine bag and the medicine cover; the sealing device is provided with a nitrogen adding device for connecting between the medicine bag and the medicine cover to replenish nitrogen;
[0011] A transfer device for transferring a medicine bag from a nitrogen filling device (3) to a melting and sealing device.
[0012] Preferably, it also includes a filling nozzle for docking with the medicine bag interface, the filling nozzle includes a vacuum joint connected to the vacuum device, a liquid filling joint connected to the liquid filling device and a nitrogen filling joint connected to the nitrogen filling device, and the vacuum joint, the liquid filling joint and the nitrogen filling joint are used to selectively connect to the medicine bag.
[0013] Preferably, the filling nozzle is an integrated structure.
[0014] Preferably, the filling nozzle comprises an inner sleeve and an outer sleeve which are independently nested, the liquid filling joint is arranged at the end of the inner sleeve, and the vacuum extraction joint and the nitrogen filling joint are both provided with the side wall of the outer sleeve.
[0015] Preferably, it also includes a lifting frame connected to the filling nozzle and used to drive the filling nozzle to insert into or disengage from the medicine bag interface.
[0016] Preferably, the nitrogen filling device comprises:
[0017] A nitrogen supply pipeline for supplying nitrogen gas;
[0018] The nitrogen filling pipeline is used to be connected with the nitrogen supply pipeline. The nitrogen filling pipeline is connected with the nitrogen filling joint through a nitrogen supply hose. The nitrogen filling pipeline is provided with a nitrogen filling control valve.
[0019] Preferably, the nitrogen filling pipeline is provided with an auxiliary pipeline for connecting to an external water supply pipeline; when the nitrogen filling control valve is opened, the nitrogen supply pipeline fills nitrogen into the nitrogen filling joint through the auxiliary pipeline; when the nitrogen filling control valve is closed, the water supply pipeline supplies water to the nitrogen filling joint through the auxiliary pipeline to clean the pipeline.
[0020] Preferably, the vacuum extraction device comprises a vacuum generator, and the vacuum generator is connected to the vacuum extraction joint via a vacuum extraction hose.
[0021] Preferably, the vacuum pumping device also includes a transition pipe connected between the nitrogen supply pipe and the vacuum generator and connected to the water supply pipe, and a vacuum control valve is provided at one end of the transition pipe connected to the nitrogen supply pipe; when the vacuum control valve is closed, the vacuum generator extracts the air in the medicine bag through the vacuum joint, or the water supply pipe supplies water to the vacuum joint through the transition pipe to clean the pipeline when the vacuum generator is closed; when the vacuum control valve is opened, the nitrogen supply pipe fills the vacuum joint with nitrogen through the transition pipe to discharge the air in the pipeline when the vacuum generator is closed.
[0022] Preferably, the device further comprises a medicine cover fixing device which is suspended above the sealing device and is used for adsorbing and fixing the medicine cover so that the medicine cover is opposite to the medicine bag.
[0023] Preferably, it also includes an exhaust device for squeezing the medicine bag during the sealing process to expel gas from the medicine bag until the volume of gas in the medicine bag reaches a preset volume.
[0024] Preferably, the nitrogen replenishing device and the nitrogen adding device are both connected to the nitrogen supply pipeline.
[0025] Compared with the background technology, the nitrogen filling equipment provided by the present invention includes a vacuuming device, a liquid filling device, a nitrogen filling device, a sealing device and a transfer device; first, the vacuuming device performs a vacuuming process on the medicine bag, and uses the vacuuming device to extract the air in the medicine bag; then, the liquid filling device fills the vacuumed medicine bag with liquid; then, the nitrogen filling device is used to fill nitrogen into the medicine bag; finally, the transfer device transfers the medicine bag from the nitrogen filling device to the sealing device, and uses the sealing device to seal the medicine bag and the medicine cover. Each production link is carried out continuously until the medicine bag is filled, which is conducive to shortening the production cycle and improving production efficiency.
[0026] In addition, the nitrogen filling device is provided with a nitrogen replenishing device, which replenishes nitrogen at the transition connection between the nitrogen filling device and the medicine bag; the sealing device is provided with a nitrogen adding device, which is connected between the medicine bag and the medicine cover for replenishing nitrogen; the nitrogen filling device and the nitrogen adding device replenish nitrogen to the medicine bag in time at different production links, respectively, to avoid the nitrogen content in the medicine bag being too low, thereby ensuring that the medicine bag has a low residual oxygen content.
[0027] Therefore, the nitrogen filling equipment provided by the present invention can improve production efficiency while ensuring a low residual oxygen content. BRIEF DESCRIPTION OF THE DRAWINGS
[0028] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.
[0029] Figure 1 A simplified structural diagram of the relevant components of a nitrogen filling device provided in a specific embodiment of the present invention;
[0030] Figure 2 for Figure 1 Partial structural diagram of the intermediate transfer device;
[0031] Figure 3 for Figure 1 Layout diagram between the fixing device, sealing device and exhaust device;
[0032] Figure 4 for Figure 1 Structural diagram of the output device in .
[0033] The reference numerals are as follows:
[0034] Medicine bag 01 and medicine cover 02;
[0035] Vacuuming device 1, filling nozzle 2, nitrogen filling device 3, sealing device 4, transfer device 5, nitrogen replenishing device 6, nitrogen adding device 7, fixing device 8, exhaust device 9 and output device 10;
[0036] A vacuum generator 11, a vacuum hose 12, a transition pipe 13 and a vacuum control valve 14;
[0037] A nitrogen supply pipeline 31, a nitrogen charging pipeline 32, a nitrogen supply hose 33, a nitrogen charging control valve 34, an auxiliary pipeline 35 and a pressure reducing valve 36;
[0038] Heating ring 41;
[0039] Bag clamp 51 and lifting frame 52;
[0040] Laminar flow sealing box 61, laminar flow hose 62, laminar flow pipeline 63 and laminar flow control valve 64;
[0041] A nitrogen adding protective sleeve 71, a nitrogen adding hose 72, a nitrogen adding pipeline 73 and a nitrogen adding control valve 74;
[0042] Clamp 101 and slide rail 102 . DETAILED DESCRIPTION
[0043] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0044] In order to enable those skilled in the art to better understand the scheme of the present invention, the present invention is further described in detail below in conjunction with the accompanying drawings and specific embodiments.
[0045] Please refer to Figures 1 to 4 , Figure 1 A simplified structural diagram of the relevant components of a nitrogen filling device provided in a specific embodiment of the present invention; Figure 2 for Figure 1 Partial structural diagram of the intermediate transfer device; Figure 3 for Figure 1 Layout diagram between the fixing device, sealing device and exhaust device; Figure 4 for Figure 1 Structural diagram of the output device in .
[0046] The embodiment of the present invention discloses a nitrogen filling device, comprising a vacuum pumping device 1, a liquid filling device, a nitrogen filling device 3, a sealing device 4 and a transfer device 5, which continuously performs vacuum pumping, liquid filling, nitrogen filling and sealing on a medicine bag to complete the filling of the medicine bag.
[0047] The vacuum device 1 uses the vacuum generator 11 to vacuum the medicine bag 01, and evacuates the air in the medicine bag 01 to prepare for filling with nitrogen. The vacuum degree of the medicine bag 01 is determined by the working time of the vacuum device 1, and the working time of the vacuum device 1 can be set as needed. After the medicine bag 01 is vacuumed, the liquid filling device quantitatively fills the medicine bag 01 with a specified liquid, and the specific filling volume can be set according to the volume of the medicine bag 01. After the medicine bag 01 is filled with liquid, the nitrogen filling device 3 quantitatively fills nitrogen into the medicine bag 01. For example, the volume of nitrogen that can be filled into the medicine bag 01 is 40-45ml, so that the residual oxygen content in the medicine bag 01 is kept within 1-2%. The volume of nitrogen filled by the nitrogen filling device 3 can be adjusted according to the specifications of the medicine bag 01, and is not specifically limited here.
[0048] The transfer device 5 is used to transfer the medicine bag 01 , and transfers the medicine bag 01 from the nitrogen filling device 3 to the sealing device 4 . The sealing device 4 seals the medicine bag 01 and the medicine cover 02 into one by local heating.
[0049] In this specific embodiment, the transfer device 5 includes a plurality of bag clamps 51 and a conveyor belt. The bag clamps 51 are used to clamp medicine bags. The plurality of bag clamps 51 are installed on the transmission belt. The transmission belt drives all bag clamps 51 to move along a linear track or a circular track, so that the medicine bag 01 moves synchronously with the bag clamps 51. Specifically, each bag clamp 51 is provided with a clamping groove, the outer side surface of the hard tube interface of the medicine bag 01 is stepped, and the inner side surface of the clamping groove is also stepped, so that the medicine bag 01 is clamped in the clamping groove by its own gravity.
[0050] During filling, the air in the medicine bag 01 is first extracted by the vacuum device 1; after the vacuum treatment, the medicine bag 01 is filled with liquid by the liquid filling device; after the liquid filling treatment, the medicine bag 01 is filled with nitrogen by the nitrogen filling device 3; the transfer device 5 transfers the medicine bag 01 from the nitrogen filling device 3 to the sealing device 4, and the sealing device 4 is used to seal the medicine bag 01 and the medicine cover 02. It can be seen that each production link is carried out continuously, so that the medicine bag 01 with a soft bag and hard tube structure is filled, which can effectively shorten the production cycle and improve production efficiency. Of course, other necessary production links can be added between each production link, which can be adjusted according to actual needs.
[0051] The nitrogen filling device 3 is provided with a nitrogen replenishing device 6, which is provided at the transition connection between the nitrogen filling device 3 and the medicine bag 01, to replenish nitrogen for the medicine bag 01, so that the medicine bag 01 is in a nitrogen environment, to prevent nitrogen leakage at the transition connection between the nitrogen filling device 3 and the medicine bag 01, and to ensure that the residual oxygen content of the medicine bag 01 meets the demand. The sealing device 4 is provided with a nitrogen adding device 7, which is connected between the medicine bag 01 and the medicine cover 02, and is used to replenish nitrogen to prevent nitrogen leakage, and also ensure that the medicine bag 01 maintains a low residual oxygen content. Therefore, the nitrogen filling device 3 and the nitrogen adding device 7 respectively replenish nitrogen to the medicine bag 01 in time at different production links, to avoid the nitrogen content in the medicine bag 01 being too low, and to ensure that the medicine bag 01 has a low residual oxygen content.
[0052] In summary, the nitrogen filling equipment provided by the present invention can improve production efficiency while ensuring a low residual oxygen content.
[0053] The present invention also includes a filling nozzle 2, which is connected to the interface of the medicine bag 01, and the filling nozzle 2 is used to fill the medicine bag 01 with liquid. In order to make the structure more compact, the filling nozzle 2 has three functional joints and a docking joint. Specifically, the three functional joints of the filling nozzle 2 are a vacuum joint, a liquid filling joint and a nitrogen charging joint. The vacuum joint is connected to the vacuum device 1, the liquid filling joint is connected to the liquid filling device, and the nitrogen charging joint is connected to the nitrogen charging device 3. The docking joint is used to connect with the medicine bag 01. The vacuum joint, the liquid filling joint and the nitrogen charging joint are selectively connected to the medicine bag 01, so that the filling nozzle 2 plays different roles in different production links, avoids adding multiple filling nozzles 2 with a single function, saves installation space, and facilitates assembly.
[0054] For easy assembly, the filling nozzle 2 is specifically an integrated structure, that is, the filling nozzle 2 is a four-way connector.
[0055] Of course, the filling nozzle 2 can be a split structure, and the filling nozzle 2 includes an inner sleeve and an outer sleeve, the inner sleeve is nested in the outer sleeve, and both the inner sleeve and the outer sleeve are hollow tubes, and the two are independent of each other, but the inner sleeve and the outer sleeve are fixedly connected at their top ends. The liquid filling joint is provided at the end of the inner sleeve, and the vacuum joint and the nitrogen filling joint are both provided with the side wall of the outer sleeve, so that the vacuum joint and the nitrogen filling joint are separated from the liquid filling joint, so that the liquid filling is not affected by the vacuum and nitrogen filling, and the quality of the liquid in the medicine bag 01 is avoided.
[0056] The present invention also includes a lifting frame 52 connected to the filling nozzle 2. The lifting frame 52 can be lifted and lowered in the vertical direction to drive the filling nozzle 2 to be inserted into or removed from the interface of the medicine bag 01. The provision of the lifting frame 52 can avoid manual insertion and removal of the filling nozzle 2, and facilitate automation. The lifting frame 52 is preferably a hydraulic cylinder. Of course, the driving method of the lifting frame 52 is not limited to this. Of course, a rotating frame can also be provided on the lifting frame 52. The rotating frame can drive the medicine bag 01 to rotate relative to the lifting frame 52, thereby adjusting the position of the filling nozzle 2 relative to the medicine bag 01 to ensure that the filling nozzle 2 is aligned with the medicine bag 01. The rotating frame can also be hydraulically driven, but is not limited to this.
[0057] The nitrogen charging device 3 includes a nitrogen supply pipeline 31 and a nitrogen charging pipeline 32. The nitrogen supply pipeline 31 is used to supply nitrogen. The two opposite ends of the nitrogen charging pipeline 32 are respectively connected to the nitrogen supply pipeline 31 and the nitrogen supply hose 33. The nitrogen supply hose 33 is connected to the nitrogen charging connector, so that the nitrogen supplied by the nitrogen supply pipeline 31 enters the medicine bag 01 through the nitrogen charging pipeline 32, the nitrogen supply hose 33 and the nitrogen charging connector in sequence. The nitrogen charging pipeline 32 is provided with a nitrogen charging control valve 34, which is used to control the nitrogen charging pipeline 32 to be on and off.
[0058] Considering that each pipeline needs to be cleaned and sterilized before filling, the nitrogen filling pipeline 32 is provided with an auxiliary pipeline 35 for externally connecting the water delivery pipeline. The nitrogen filling pipeline 32 is in an inverted T shape. Both ends of the auxiliary pipeline 35 are respectively connected to the water delivery pipeline, and the nitrogen filling pipeline 32 is vertically connected to the auxiliary pipeline 35. The nitrogen filling control valve 34 is specifically arranged at one end of the nitrogen filling pipeline 32 close to the nitrogen supply pipeline 31. The nitrogen filling control valve 34 is specifically a pneumatic valve. The nitrogen filling pipeline 32 is also provided with a pressure reducing valve 36, and the pressure reducing valve 36 is used to adjust the air pressure of the nitrogen filling pipeline 32.
[0059] When the nitrogen filling control valve 34 is opened, the nitrogen supplied by the nitrogen supply pipeline 31 is sequentially filled into the medicine bag 01 through the nitrogen filling pipeline 32, the auxiliary pipeline 35, the nitrogen supply hose 33 and the nitrogen filling joint to achieve nitrogen filling. When the nitrogen filling control valve 34 is closed, the auxiliary pipeline 35 is connected to the water delivery pipeline, so that the water supplied by the water delivery pipeline sequentially flows into the nitrogen filling joint through the auxiliary pipeline 35 and the nitrogen supply hose 33, and then is discharged from the nitrogen filling joint, which is convenient for cleaning the pipeline of the nitrogen filling device 3 before filling. Of course, the nitrogen filling control valve 34 can also be opened before filling, and the nitrogen supplied by the nitrogen supply pipeline 31 is filled into the nitrogen filling pipeline 32, the auxiliary pipeline 35, the nitrogen supply hose 33 and the nitrogen filling joint, and the air in each pipeline is emptied, which is conducive to reducing the residual oxygen content of the medicine bag 01.
[0060] In order to make the structure more compact, the nitrogen replenishing device 6 and the nitrogen adding device 7 are both connected to the nitrogen supply pipeline 31 .
[0061] In this specific embodiment, the nitrogen replenishing device 6 is specifically a laminar flow nitrogen replenishing device, which can provide nitrogen with uniform flow rate to avoid drastic changes in the volume of nitrogen in the medicine bag 01. The laminar flow nitrogen replenishing device specifically includes a laminar flow sealing box 61, a laminar flow hose 62 and a laminar flow pipeline 63. The laminar flow pipeline 63 is vertically connected to the nitrogen supply pipeline 31. The laminar flow pipeline 63 is also provided with a laminar flow control valve 64, and the laminar flow control valve 64 is used to control the on and off of the laminar flow pipeline 63. During the nitrogen filling process, the laminar flow control valve 64 must remain open to ensure that the medicine bag 01 is in a sufficient nitrogen environment. The laminar flow control valve 64 can also be a pneumatic valve. The laminar flow hose 62 is connected between the laminar flow pipeline 63 and the laminar flow sealing box 61, so that the nitrogen supply pipeline 31 provides nitrogen to the laminar flow sealing box 61 through the laminar flow hose 62. The laminar flow sealing box 61 seals and isolates the transition connection between the plurality of nitrogen filling devices 3 and the medicine bag 01 , provides a nitrogen environment for the interface of the medicine bag 01 , and prevents the nitrogen in the medicine bag 01 from being reduced.
[0062] The nitrogen adding device 7 includes a nitrogen adding protective sleeve 71, a nitrogen adding hose 72 and a nitrogen adding pipeline 73. The nitrogen adding pipeline 73 is vertically connected to the nitrogen supply pipeline 31. The nitrogen adding pipeline 73 is also provided with a nitrogen adding control valve 74, and the nitrogen adding control valve 74 is used to control the opening and closing of the nitrogen adding pipeline 73. When the medicine bag 01 is melt-sealed, the nitrogen adding control valve 74 must be kept open. The nitrogen adding control valve 74 can also be a pneumatic valve. The nitrogen adding hose 72 is connected between the nitrogen adding protective sleeve 71 and the nitrogen adding pipeline 73, so that the nitrogen adding pipeline 73 provides nitrogen to the nitrogen adding protective sleeve 71 through the nitrogen adding hose 72. The nitrogen adding protective sleeve 71 is connected between the medicine bag 01 and the medicine cover 02, and the connection between the medicine bag 01 and the medicine cover 02 is sealed and isolated, and a nitrogen environment can still be provided for the medicine bag 01 to prevent the nitrogen in the medicine bag 01 from being reduced.
[0063] The vacuum device 1 includes a vacuum generator 11, which is connected to the vacuum joint through a vacuum hose 12. When the vacuum generator 11 is turned on, the vacuum generator 11 extracts the air in the medicine bag 01. In order to adapt to the cleaning process before filling, the vacuum device 1 also includes a transition pipe 13. The transition pipe 13 is in an inverted T shape, and its upper and lower ends are respectively connected to the nitrogen supply pipe 31 and the vacuum generator 11, and its left and right ends are connected to the water supply pipe. The vacuum generator 11 is vertically connected to the end of the water supply pipe away from the transition pipe 13. A vacuum control valve 14 is provided at one end of the transition pipe 13 connected to the nitrogen supply pipe 31. The vacuum control valve 14 is used to control the on and off of the transition pipe 13.
[0064] When the vacuum control valve 14 is closed, it means that the nitrogen supply pipeline 31 is disconnected from the vacuum joint. At this time, the vacuum generator 11 is opened, and the vacuum generator 11 extracts the air in the medicine bag 01 through the vacuum joint when the filling nozzle 2 is connected to the medicine bag 01. Alternatively, when the vacuum control valve 14 and the vacuum generator 11 are both closed, that is, when the filling nozzle 2 is not connected to the medicine bag 01 before filling, the water provided by the water pipeline flows to the vacuum joint through the transition pipeline 13 and the vacuum hose 12 in turn, and is discharged from the vacuum joint to use the water to clean the pipelines. When the vacuum control valve 14 is opened, the vacuum control valve 14 is closed, and the nitrogen supplied by the nitrogen supply pipeline 31 is filled with nitrogen through the transition pipeline 13, the vacuum hose 12 and the vacuum joint in turn to discharge the air in the pipeline.
[0065] It should be noted that before filling, the nitrogen filling device 3 and the vacuum device 1 need to use water to clean the pipeline, and nitrogen needs to be used to exhaust the air in the pipeline to prevent impurities or excess oxygen in the pipeline from entering the medicine bag 01 during the filling process, which is beneficial to improving production quality.
[0066] The present invention also includes a fixing device 8 suspended above the sealing device 4, and the fixing device 8 uses negative pressure to absorb and fix the medicine cover 02, so that the medicine cover 02 is opposite to the medicine bag 01. The fixing device 8 includes a negative pressure sleeve, and the negative pressure sleeve is provided with a limit groove for accommodating the medicine cover 02, and the limit groove is provided with a negative pressure through hole connected to the vacuum pump, so that the limit groove uses the negative pressure provided by the vacuum pump to absorb and fix the medicine cover 02. The fixing device 8 also includes a lifting component and a translation component, the lifting component is used to drive the negative pressure sleeve to lift and lower in the vertical direction, and the translation component is used to drive the negative pressure sleeve to translate along the horizontal plane, so that the fixing device 8 drives the medicine cover 02 one by one to approach or move away from the interface of the medicine bag 01, ensuring that the medicine cover 02 is aligned with the interface of the medicine bag 01.
[0067] The present invention further includes an exhaust device 9. During the sealing process, when the volume of gas remaining in the medicine bag 01 exceeds a preset volume, the exhaust device 9 is activated, and the exhaust device 9 squeezes the medicine bag 01 to discharge gas from the medicine bag 01 until the volume of gas in the medicine bag 01 reaches a preset volume. The preset volume here refers to the maximum volume of gas contained in the medicine bag 01, which is mainly set according to the specifications of the medicine bag 01. In this specific embodiment, the exhaust device 9 includes an exhaust plate and an exhaust drive cylinder for driving the exhaust plate to move. The exhaust drive cylinder drives the exhaust plate to press the exhaust plate toward the medicine bag 01 by telescoping, and can also drive the exhaust plate to move back and forth along the length direction of the medicine bag 01 to squeeze out excess gas in the medicine bag 01. The present invention can also include a controller and a pressure sensor for detecting the pressure of the medicine bag 01, and indirectly obtain the volume of gas in the medicine bag 01 through the pressure information obtained by the pressure sensor. The pressure sensor and the exhaust drive cylinder are electrically connected to the controller, and the controller automatically starts the exhaust drive cylinder when the volume of gas in the medicine bag 01 exceeds the preset volume according to the signal sent by the pressure sensor.
[0068] The sealing device 4 in the present invention includes a heating ring 41. The heating ring 41, the nitrogen protection sleeve 71, the medicine cover 02 and the medicine bag 01 are coaxially arranged. The heating ring 41 is used to heat the opposite ends of the medicine cover 02 and the medicine bag 01 respectively, so that the two are melted and adhered to each other, thereby making the medicine cover 02 and the medicine bag 01 fixedly connected as a whole. The sealing device 4 also includes a sealing moving component connected to the heating ring 41. The sealing moving component is connected to the heating ring 41. The sealing moving component is used to drive the heating ring 41 to move back and forth, so that the heating ring 41 is aligned with the medicine cover 02 and the medicine bag 01 when working. Of course, the structure of the sealing device 4 is not limited to this.
[0069] The present invention further includes an output device 10 connected to the transfer device 5. When the medicine cap 02 and the medicine bag 01 are filled, the output device 10 clamps the medicine cap 02 and transports the filled medicine bag 01 to the next production link. In this specific embodiment, the output device 10 includes a clamp 101, a slide rail 102 and an output drive cylinder. The clamp 101 is used to clamp the medicine cap 02. The clamp 101 is slidably arranged on the slide rail 102, so that the clamp 101 drives the medicine cap 02 to move along the slide rail 102 under the drive of the output drive cylinder, and outputs the filled medicine bag 01.
[0070] The working principle of the nitrogen filling equipment provided by the present invention is as follows:
[0071] Before filling, the filling nozzle 2 is not connected to the medicine bag 01;
[0072] When the nitrogen filling control valve 34 is closed, the auxiliary pipeline 35 is connected to the water delivery pipeline, and the water supplied by the water delivery pipeline flows into the nitrogen filling joint through the auxiliary pipeline 35 and the nitrogen supply hose 33 in turn, and is then discharged from the nitrogen filling joint to clean the pipeline of the nitrogen filling device 3; when the nitrogen filling control valve 34 is opened, the nitrogen supplied by the nitrogen supply pipeline 31 fills the nitrogen filling pipeline 32, the auxiliary pipeline 35, the nitrogen supply hose 33 and the nitrogen filling joint, and the air in each pipeline is emptied; when the vacuum control valve 14 and the vacuum generator 11 are both closed, the water provided by the water delivery pipeline flows to the vacuum joint through the transition pipeline 13 and the vacuum hose 12 in turn, and is discharged from the vacuum joint to clean the pipelines of the vacuum device 1; when the vacuum control valve 14 is opened and the vacuum control valve 14 is closed, the nitrogen supplied by the nitrogen supply pipeline 31 is filled with nitrogen through the transition pipeline 13, the vacuum hose 12 and the vacuum joint in turn to discharge the air in the pipeline;
[0073] During filling, the filling nozzle 2 is connected to the medicine bag 01. First, when the vacuum control valve 14 is closed, the vacuum generator 11 is opened, and the vacuum generator 11 extracts the air in the medicine bag 01 through the vacuum joint. Then, the liquid filling device fills the vacuumed medicine bag 01 with liquid through the liquid filling joint. Then, the nitrogen filling control valve 34 is opened, and the nitrogen supplied by the nitrogen supply pipeline 31 is filled into the filled medicine bag 01 through the nitrogen filling pipeline 32, the auxiliary pipeline 35, the nitrogen supply hose 33 and the nitrogen filling joint in turn; the laminar flow control valve 64 is opened, and the nitrogen supply pipeline 31 supplies nitrogen to the laminar flow sealing box 61 through the laminar flow hose 62, providing a nitrogen environment for the interface of the medicine bag 01. Finally, the transfer device 5 transfers the medicine bag 01 to the sealing device 4, and uses the sealing device 4 to seal the medicine bag 01 and the medicine cover 02, so that the medicine cover 02 and the medicine bag 01 are fixedly connected as one; the nitrogen adding control valve 74 is opened, and the nitrogen adding pipeline 73 supplies nitrogen to the nitrogen adding protective sleeve 71 through the nitrogen adding hose 72, so as to provide a nitrogen environment for the medicine bag 01; at the same time, the exhaust device 9 is started, and the exhaust device 9 squeezes the medicine bag 01, and the medicine bag 01 discharges gas until the gas volume in the medicine bag 01 reaches the preset volume;
[0074] The output device 10 is started to transport the filled medicine bag 01 to the next production link.
[0075] The nitrogen filling equipment provided by the present invention is introduced in detail above. Specific examples are used in this article to illustrate the principle and implementation mode of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for those skilled in the art, according to the idea of the present invention, there will be changes in the specific implementation mode and application scope. In summary, the content of this specification should not be understood as limiting the present invention.
Claims
1. A nitrogen filling device, characterized in that: include: A vacuum device (1) for extracting air from a medicine bag (01); A liquid filling device for filling the vacuumed medicine bag (01) with liquid; a nitrogen filling device (3) for filling nitrogen into the liquid-filled medicine bag (01); the nitrogen filling device (3) is provided with a nitrogen replenishing device (6) for replenishing nitrogen at the transition connection between the nitrogen filling device (3) and the medicine bag (01); A sealing device (4) for sealing a medicine bag (01) and a medicine cap (02); the sealing device (4) is provided with a nitrogen supply device (7) for connecting between the medicine bag (01) and the medicine cap (02) to replenish nitrogen; A transfer device (5) for transferring the medicine bag (01) from the nitrogen filling device (3) to the sealing device (4); a filling nozzle (2) for docking with the interface of the medicine bag (01), the filling nozzle (2) comprising a vacuum joint connected to the vacuum device (1), a liquid filling joint connected to the liquid filling device, and a nitrogen filling joint connected to the nitrogen filling device (3), the vacuum joint, the liquid filling joint, and the nitrogen filling joint being used to selectively connect to the medicine bag (01); The nitrogen filling device (3) comprises: a nitrogen supply pipeline (31) for supplying nitrogen gas; a nitrogen filling pipeline (32) for being connected to the nitrogen supply pipeline (31), the nitrogen filling pipeline (32) being connected to the nitrogen filling joint via a nitrogen supply hose (33), and the nitrogen filling pipeline (32) being provided with a nitrogen filling control valve (34); The nitrogen charging pipeline (32) is provided with an auxiliary pipeline (35) for connecting to an external water supply pipeline; when the nitrogen charging control valve (34) is opened, the nitrogen supply pipeline (31) charges the nitrogen charging joint with nitrogen through the auxiliary pipeline (35); when the nitrogen charging control valve (34) is closed, the water supply pipeline supplies water to the nitrogen charging joint through the auxiliary pipeline (35) to clean the pipeline; The nitrogen replenishing device (6) and the nitrogen adding device (7) are both connected to the nitrogen supply pipeline (31).
2. The nitrogen filling equipment according to claim 1, characterized in that: The filling nozzle (2) is specifically an integrated structure.
3. The nitrogen filling equipment according to claim 1, characterized in that: The filling nozzle (2) comprises an inner sleeve and an outer sleeve which are independently nested, the liquid filling joint is arranged at the end of the inner sleeve, and the vacuum extraction joint and the nitrogen filling joint are both arranged on the side wall of the outer sleeve.
4. The nitrogen filling equipment according to claim 2, characterized in that: It also includes a lifting frame (52) connected to the filling nozzle (2) and used to drive the filling nozzle (2) to insert into or detach from the interface of the medicine bag (01).
5. The nitrogen filling equipment according to claim 1, characterized in that: The vacuum extraction device (1) comprises a vacuum generator (11), and the vacuum generator (11) is connected to the vacuum extraction joint via a vacuum extraction hose (12).
6. The nitrogen filling equipment according to claim 5, characterized in that: The vacuum pumping device (1) further comprises a transition pipe (13) connected between the nitrogen supply pipe (31) and the vacuum generator (11) and connected to the water supply pipe, and a vacuum control valve (14) is provided at one end of the transition pipe (13) connected to the nitrogen supply pipe (31); when the vacuum control valve (14) is closed, the vacuum generator (11) is used to extract the air in the medicine bag (01) through the vacuum pumping joint, or the water supply pipe is used to supply water to the vacuum pumping joint through the transition pipe (13) to clean the pipeline when the vacuum generator (11) is closed; when the vacuum control valve (14) is opened, the nitrogen supply pipe (31) is used to fill the vacuum pumping joint with nitrogen through the transition pipe (13) to discharge the air in the pipeline when the vacuum generator (11) is closed.
7. The nitrogen filling equipment according to any one of claims 1 to 6, characterized in that: It also includes a fixing device (8) for the medicine cover (02) which is suspended above the sealing device (4) and is used for adsorbing and fixing the medicine cover (02) so that the medicine cover (02) is opposite to the medicine bag (01).
8. The nitrogen filling equipment according to any one of claims 1 to 6, characterized in that: It also includes an exhaust device (9) for squeezing the medicine bag (01) during the sealing process to allow the medicine bag (01) to exhaust gas until the volume of gas in the medicine bag (01) reaches a preset volume.
Citation Information
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