A kind of preparation method and application of ultrafine uniform acrylamide polymer hydrogel silk

An acrylamide copolymer and acrylamide copolymerization technology, applied in the medical field, can solve problems such as difficulty, small breaking force value, and difficult wire drawing processing, so as to reduce the number of uses, reduce the occupying effect, reduce the recurrence rate and relapse The effect of treatment rate

CN112300413BActive Publication Date: 2021-04-09BEIJING TAIJIE WEIYE TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2021-04-09

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Abstract

The invention relates to a preparation method of ultrafine and uniform acrylamide polymer hydrogel filaments, comprising: configuring a reaction solution of acrylamide polymer under ice bath conditions, and sucking the reaction solution into a polymerization reaction tube through a syringe; The two ends of the polymerization reaction tube are facing upwards, and the parabolic bending is performed; the polymerization reaction tube is suspended for 2h-8h, and the baking reaction is carried out to obtain the acrylamide polymer hydrogel; the polymerization reaction tube is vacuum-dried for 4h-8h to obtain Acrylamide polymer dry filament; the polymerization reaction tube is cut into sections to obtain multiple short polymerization reaction tubes with preset lengths; the acrylamide polymer dry filament is pushed out of the short polymerization reaction tube through a stainless steel wire; purification is carried out in the immersion solution to obtain an acrylamide polymer expansion filament; and to dry naturally to obtain an acrylamide polymer hydrogel filament with a preset outer diameter. The hydrogel filaments prepared by this method are ultrafine and uniform.
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Description

technical field

[0001] The invention relates to the field of medical technology, in particular to a preparation method and application of ultrafine and uniform acrylamide polymer hydrogel filaments. Background technique

[0002] Aneurysm is a very common vascular disease, which is caused by the lesion or injury of the arterial wall, resulting in localized or diffuse expansion or bulging of the arterial wall. any part of the system. Once an aneurysm ruptures, serious consequences may result. Such as intracranial aneurysm rupture, resulting in subarachnoid hemorrhage, severe cases can cause vasospasm and large-scale cerebral infarction, resulting in hemiplegia and coma. The current treatment options for aneurysms mainly include open surgery and endovascular intervention. The open surgical treatment plan needs to open the body cavity surrounding the aneurysm, such as craniotomy and thoracotomy, which will cause huge damage to the patient's body, and the postoperative recover...

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Embodiment Construction

[0029] In order to make the purpose, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings. Obviously, the described embodiments are only some of the embodiments of the present invention, rather than all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0030] Embodiment 1 of the present invention provides a method for preparing ultra-fine and uniform acrylamide polymer hydrogel filaments. The reaction solution of acrylamide polymer is prepared under ice bath conditions, and sucked into the polymerization reaction tube. The parabolic suspension of the polymerization reaction tube is carried out in a constant temperature drying oven for baking reaction, so that the reaction solution is f...