A centrifugal assembly capable of adjusting the centrifugal degree of filtered liquid

Abstract

The present invention belongs to the field of analytical chemistry, and relates to a centrifugal assembly (100) capable of adjusting the centrifugal degree of filtered liquid, comprising a filter tube (101), a sleeve (102) for placing the filter tube (101), and a fixing member (103) for fixing the sleeve (102) on a centrifugal tube (107); wherein an outlet (120) is provided at the bottom of the filter tube (101) to connect the filter tube (101) with the sleeve (102); and a liquid level control hole (104) is provided on the tube wall of the sleeve (102), and the liquid level control hole (104) penetrates the tube wall of the sleeve (102) to connect the sleeve (102) with the centrifugal tube (107). By adjusting the height of the liquid level control hole (104), the height of the liquid level of the filtered liquid (200) during and at the end of the centrifugation process can be adjusted, thereby simply and conveniently realizing the adjustment and control of the centrifugal degree, which is conducive to realizing the standardized operation of centrifugation.

Description

Technical Field

[0001] The invention belongs to the field of analytical chemistry, and in particular relates to a centrifugal component capable of adjusting the centrifugal degree of filtered liquid. Background Art

[0002] In industrial production and experimental analysis, centrifugal force is usually used instead of manpower, that is, through the centrifugal process, the filtered liquid can be separated, enriched or purified. In some application scenarios where filter fillers are used for centrifugal filtration, it is necessary to ensure that the filter fillers are always wet during the centrifugation process. This requires that a portion of the filtered liquid is always slightly higher than the filter filler (that is, the surface of the filtered liquid after centrifugation is still slightly higher than the surface of the filter filler), so as to ensure the degree of centrifugation of the filtered liquid during the centrifugation process.

[0003] In addition, in some experiments that require monitoring using a solid phase extraction column (SPE column), since the tube is small, the amount of filter filler loaded each time is also small (for example, tens of milligrams), so it is difficult to keep the amount of filter filler loaded in the solid phase extraction column completely consistent each time. Therefore, in the conventional centrifugation process, it is difficult to ensure that the surface of the filtered liquid is slightly higher than the surface of the filter filler after the same filtered liquid is treated for the same time. In other words, it is difficult to achieve standardization and automation of the centrifugation process, and it is also difficult to achieve effective regulation of the centrifugation degree of the filtered liquid.

[0004] Currently, in the prior art, there is no centrifugal assembly that can conveniently and quickly adjust the centrifugal degree of the filtered liquid and effectively realize the standardization and automation of the centrifugal operation. Summary of the invention

[0005] In order to solve the above technical problems, the present invention provides a centrifugal assembly capable of adjusting the degree of centrifugation of filtered liquid, characterized in that it comprises a filter tube, a sleeve for placing the filter tube, and a fixing member for fixing the sleeve on the centrifuge tube; wherein an outlet is provided at the bottom of the filter tube to connect the filter tube and the sleeve; and a liquid level control hole is provided on the tube wall of the sleeve, wherein the liquid level control hole penetrates the tube wall of the sleeve to connect the sleeve with the centrifuge tube.

[0006] In some embodiments, the diameter of the sleeve is larger than the diameter of the filter tube, and a protrusion structure is provided on the outer side of the tube wall of the filter tube to stably clamp the filter tube in the sleeve.

[0007] In some embodiments, the centrifugal assembly further comprises: a filter filler and a filter membrane, wherein the filter filler is loaded in a filter tube; and the filter membrane is placed at the bottom of the filter tube to cover the outlet.

[0008] In some embodiments, the filter tube and the sleeve are of gun head type.

[0009] In some embodiments, the filter tube and the sleeve are cylindrical.

[0010] In some embodiments, the diameter range of the liquid level control hole is: 0.1mm-0.5mm.

[0011] In some embodiments, the vertical height range of the liquid level control hole from the outlet is: 5mm-9mm.

[0012] In some embodiments, the vertical height range of the liquid level control hole from the outlet is: 10mm-14mm.

[0013] In some embodiments, the centrifugal assembly includes a first slide rail mechanism, which includes a first slide, a second slide and a slide guide, the first slide and the second slide can slide on the slide guide, the slide guide is provided with a hollow groove that penetrates the wall of the casing, and the liquid level control hole is located between the first slide and the second slide.

[0014] In some embodiments, the centrifugal assembly includes a second slide rail mechanism, the second slide rail mechanism includes a third slide and a slide rail, the third slide is provided with the liquid level control hole, and the slide rail is provided with a hollow groove penetrating the sleeve wall. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The accompanying drawings are used to provide a further understanding of the present invention and are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation of the present invention. In the accompanying drawings:

[0016] Figure 1 It is an embodiment of the gun head type sleeve of the present invention;

[0017] Figure 2 This is an embodiment of the solid phase extraction casing of the present invention;

[0018] Figure 3 An embodiment of the present invention using multiple liquid level control holes;

[0019] Figure 4a This is an embodiment of the present invention that uses the first slide rail mechanism to adjust the liquid level control hole;

[0020] Figure 4b This is an embodiment of the present invention that uses a second slide rail mechanism to adjust the liquid level control hole;

[0021] Figure 4c An embodiment of the hollow groove structure in the slide rail is shown;

[0022] Figure 5An embodiment of the present invention;

[0023] Figure 6 An embodiment of the present invention;

[0024] Figure 7 This is an example of actual use of the tip-type centrifuge assembly.

[0025] The components of the present invention include: a centrifugal component 100, a filter tube 101, a sleeve 102, a fixing part 103, a liquid level control hole 104, a filter filler 105, a filter membrane 106, a centrifugal tube 107, an adsorbent material 108, a plugging part 109, a slide rail 110, a first slide 111, a second slide 112, a third slide 113, a hose 114, a hose cover 115, an outlet 120, a sleeve cover 122, a protrusion structure 124, a through hole 126, a filter membrane 128, a hollow groove 130, and a filtered liquid 200. DETAILED DESCRIPTION

[0026] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0027] The present invention discloses a centrifugal assembly 100 capable of adjusting the centrifugal degree of filtered liquid. Figure 1 As shown, the centrifugal assembly includes a filter tube 101, a sleeve 102 for placing the filter tube 101, and a fixing member 103 for fixing the sleeve 102 in a centrifugal tube 107. The fixing member 103 is provided with a through hole 126 at its center. The sleeve 102 can be stably placed on the fixing member 103 through the through hole 126. The bottom of the filter tube 101 is provided with an outlet 120 to connect the filter tube 101 and the sleeve 102; and a liquid level control hole 104 is provided on the tube wall of the sleeve 102, and the liquid level control hole 104 penetrates the tube wall of the sleeve 102 and connects the sleeve 102 and the centrifugal tube 107.

[0028] The diameter of the casing 102 is larger than the diameter of the filter tube 101, so that the filter tube 101 can be placed in the casing 102 (more specifically, the inner diameter of the casing 102 is larger than the outer diameter of the filter tube 101, so that the filter tube 101 can be placed in the casing 102). In some embodiments, the filter tube 101 is provided with a protruding structure 124 on the outer wall near its tube opening, which can stably clamp the filter tube 101 in the casing 102, prevent the bottom of the filter tube 101 from contacting the bottom of the casing 102, and prevent the outlet 120 from being blocked.

[0029] The wall of the sleeve 102 is provided with a liquid level control hole 104. The liquid level control hole 104 penetrates the wall of the sleeve 102, so that the interior of the sleeve 102 is connected with the interior of the centrifuge tube 107. The bottom of the filter tube 101 is provided with an outlet 120, so that the filter tube 101 is connected with the sleeve 102 (that is, the liquid can flow out of the filter tube 101 through the outlet 120 and flow into the sleeve 102).

[0030] During actual use, the filter tube 101 is first placed in the sleeve 102; then the sleeve 102 is inserted into the through hole 126 of the fixing member 103, so that the sleeve 102 is stably fixed on the fixing member 103; finally, the fixing member 103 is inserted into a centrifuge tube 107 of appropriate size (the outer size of the fixing member 103 matches the inner diameter of the opening of the centrifuge tube 107, and can be firmly and tightly clamped at the opening of the centrifuge tube 107), completing the assembly of the centrifuge assembly 100.

[0031] When a centrifugal experiment is required, firstly, a proper amount of filter filler 105 is added into the filter tube 101, and the filter filler 105 is stably deposited at the bottom of the filter tube 101 (for example, the centrifugal assembly 100 can be first subjected to low-speed centrifugal rotation by a low-speed centrifugal device to allow the filter filler 105 to be concentrated at the bottom of the filter tube 101, thereby avoiding the filter filler 105 from remaining on the tube wall); then, a proper amount of filtered liquid 200 is injected into the filter tube 101 and allowed to stand for a certain period of time, and then the centrifugal assembly 100 is placed in a centrifuge as a whole for centrifugation.

[0032] In some practical applications, such as Figure 7 As shown, a method for using a centrifugal assembly 100 capable of adjusting the centrifugal degree of filtered liquid is disclosed, comprising the following steps:

[0033] S101: placing the filter tube 101 in the casing 102;

[0034] S102: adding a proper amount of filter filler 105 into the filter tube 101 and stably stacking it at the bottom of the filter tube 101, and then injecting a proper amount of filter liquid 200 into the filter tube 101 and letting it stand for a certain period of time;

[0035] S103: inserting the sleeve 102 into the through hole 126 of the fixing member 103, so as to fix the sleeve 102 on the fixing member 103;

[0036] S104: inserting the fixing member 103 into a centrifuge tube 107 of suitable size (the outer size of the fixing member 103 matches the inner diameter of the opening of the centrifuge tube 107 and can be firmly and tightly stuck in the opening of the centrifuge tube 107);

[0037] S105: placing the centrifugal assembly 100 as a whole into a centrifuge for centrifugation;

[0038] S106: After the centrifugation is completed, the centrifugal assembly 100 is taken out;

[0039] S107: Disassemble the centrifugal assembly 100 and take out the filter tube 101 and the sleeve 102.

[0040] During the centrifugation process, under the action of centrifugal force, the filtered liquid 200 in the filter tube 101 will first flow through the filter filler 105, and then flow into the sleeve 102 through the outlet 120. As the centrifugation proceeds, the liquid level in the sleeve 102 gradually rises. When the height reaches the height of the liquid level control hole 104, the filtered liquid can flow out of the liquid level control hole 104 and enter the centrifuge tube 107 (in other words, the liquid level in the sleeve 102 will always be maintained at the height of the liquid level control hole 104). Based on the principle of communicating vessels, if the height of the liquid level control hole 104 is set at a position higher than the filter filler 105, the liquid level of the filtered liquid 200 in the filter tube 101 will always be maintained at the same height as the liquid level control hole 104, so that the liquid level of the filtered liquid 200 is always higher than the surface of the filter filler 105 during the centrifugation process. This avoids the situation where the liquid level of the filtered liquid 200 is lower than the surface of the filter filler 105 due to excessive centrifugation. Furthermore, by adjusting the height of the position of the liquid level control hole 104, the volume of the filtered liquid 200 reserved in the filter tube 101 can be adjusted, thereby realizing the control and adjustment of the centrifugal degree of the filtered liquid 200 (that is, when the volume of the filtered liquid 200 is the same, if the volume of the filtered liquid 200 reserved is smaller, then the centrifugal degree is higher; on the contrary, if the volume of the filtered liquid 200 reserved is larger, then the centrifugal degree is lower).

[0041] In the present invention, "degree of centrifugation" refers to the ratio of ΔV (i.e., the difference between the volume V1 of the filtered liquid 200 before centrifugation and the volume V2 of the filtered liquid 200 after centrifugation) to the volume of the filtered liquid 200 before centrifugation. The closer the ratio is to 100%, the higher the degree of centrifugation is; and the closer the ratio is to 0, the lower the degree of centrifugation is. For example, if the volume V1 of the filtered liquid 200 is 10 mL and the volume V2 of the filtered liquid 200 after centrifugation is 2 mL, then the degree of centrifugation is

[0042] In some embodiments of the present invention, Figure 1 As shown, the outlet 120 at the bottom of the filter tube 101 is covered with a filter membrane 106, which can prevent the filter filler 105 from falling out of the filter tube 101 (especially when the filter filler 105 is composed of particles with a smaller diameter), and can also achieve secondary filtration outside the filter filler 105 in certain experimental scenarios.

[0043] In some embodiments, Figure 1 As shown, an adsorbent material 108 (e.g., absorbent cotton) is provided at the bottom of the centrifuge tube 107 to adsorb the filtered liquid 200 that flows into the centrifuge tube 107 from the liquid level control hole 104 during the centrifugation process, so as to prevent the filtered liquid 200 from splashing during (i) the centrifugation process and (ii) when the fixing member 103 is removed from the centrifuge tube 107 after the centrifugation is completed (especially when toxic and contaminated liquids are involved, preventing liquid splashing is an important consideration).

[0044] In addition, when the filtered liquid 200 containing multiple substances (i.e., the solution of the filtered liquid 200 contains both high-density substances and low-density substances) is centrifuged, the filtered liquid 200, under the action of centrifugal force, combined with the dual filtering effect of the filter filler 105 and the filter membrane 106, the substances with higher density will first be filtered through the filter filler 105 and the filter membrane 106 to enter the sleeve 102; while the substances with lower density will pass through the filter filler 105 and the filter membrane 106 relatively slowly, so that the centrifugal component 100 of the present invention can achieve the separation of substances with different densities in the filtered liquid 200 to a certain extent. Moreover, even if some of the substances with lower density quickly enter the sleeve 102 due to a long centrifugal time or a high centrifugal speed (strong centrifugal force), the substances with higher density in the filtered liquid 200 will be deposited at the bottom of the sleeve 102, while the substances with lower density in the filtered liquid 200 will be separated and float in the middle and upper layers of the liquid in the sleeve 102, or even flow out through the liquid level control hole 104 into the centrifuge tube 107, thereby achieving the separation of substances with different densities. If the substances with lower density need to be separated and retained, they can be collected in the centrifuge tube 107; if they do not need to be collected (for example, especially toxic and harmful impurities), they can be adsorbed by the adsorption material 108 placed at the bottom of the centrifuge tube 107, such as absorbent cotton, to avoid splashing and facilitate subsequent experimental waste treatment.

[0045] In some specific embodiments, Figure 5 As shown, a small section of conduit 114 is provided at the outer end of the liquid level control hole 104 to guide the liquid to flow out smoothly from the liquid level control hole 104, so as to avoid unexpected situations such as the liquid being unable to flow out smoothly through the liquid level control hole 104 during the centrifugation process due to high liquid viscosity or high liquid surface tension, thereby rendering the function of the liquid level control hole 104 ineffective.

[0046] In some specific embodiments, Figure 6 As shown, a filter membrane 128 is also provided in the liquid level control hole 104. Only when the volume of the liquid in the sleeve 102 reaches a certain volume, the liquid can pass through the filter membrane 128 and flow into the centrifuge tube 107. In other embodiments, the filter membrane 128 is used in the liquid level control hole 104 to perform multiple filtrations on the filtered liquid 200, so that a part of the material remains in the sleeve 102 to complete the collection, and another part of the material that can pass through the filter membrane 128 is filtered into the centrifuge tube 107, thereby achieving effective separation of multiple materials during the centrifugation process.

[0047] In some embodiments, the filter filler 105 includes one or more of metal filter mesh, artificial fiber, pebbles, quartz sand, zeolite, volcanic rock, ceramsite, activated carbon, anthracite and ion exchange resin.

[0048] In some embodiments, filter membrane 106 and filter membrane 128 include one or more of ultrafiltration membrane, microporous filter membrane, nanofiltration membrane, microfiltration membrane, hollow fiber ultrafiltration membrane, and Purcell filter membrane.

[0049] In a specific embodiment of the present invention, the diameter of the liquid level control hole 104 in the sleeve 102 ranges from 0.1 mm to 0.5 mm, which is conducive to the smooth outflow of liquid.

[0050] In some specific embodiments of the present invention, the sleeve 102 adopts a gun head type similar to a cone shape (it can also be called a filter gun head sleeve), and the height range of the liquid level control hole 104 is set at a vertical distance of 5mm-9mm from the bottom of the sleeve 102 (i.e., the outlet 120). For example, take the filter gun head sleeve 102 with a filler height of 5mm and a volume of 100μL as an example. The size of the sleeve 102 is 5cm long, the upper bottom surface diameter is 9mm, the lower bottom surface diameter is 2mm, and the opening height of the liquid level control hole 104 is 7mm from the bottom surface. Of course, according to different experimental requirements, the height of the liquid level control hole 104 can be adjusted to make the liquid level of the filtered liquid 200 after centrifugation slightly higher than the surface of the filter filler 105 in a simpler and more convenient way, thereby adjusting the degree of centrifugation of the filtered liquid 200.

[0051] In some embodiments, Figure 2 As shown, the vertical height range of the liquid level control hole 104 on the sleeve 102 in the cylindrical centrifugal assembly 100 is 10 mm-14 mm. For example, taking a solid phase extraction column (SPE column) with a filter filler 105 height of 10 mm and a volume of 6 mL as an example, the size of the sleeve 102 is 10 cm long, and the upper and lower bottom diameters are both 15 mm, and the position height of the liquid level control hole 104 is 12 mm from the bottom surface of the solid phase extraction column (SPE column).

[0052] In some specific embodiments of the present invention, Figure 3 As shown, a plurality of liquid level control holes 104 are provided at different height positions of the side wall of the sleeve 102. According to the actual needs of the experiment, a liquid level control hole 104 with a suitable height can be selected, and the remaining liquid level control holes 104 can be sealed with a plugging member 109 (for example, waterproof tape, plastic plug), that is, only one liquid level control hole 104 with a suitable height is left to adjust the centrifugal degree; or, in some experiments, only the liquid level control hole 104 with a height lower than the height of the selected liquid level control hole 104 can be sealed (because generally speaking, the liquid level will not be higher than the selected liquid level control hole 104, and naturally it will not flow out from the liquid level control hole 104 at a higher position). The plugging member 109 used should have good sealing, waterproof and corrosion resistance to prevent the filtered liquid from flowing out.

[0053] In some specific embodiments of the present invention, the liquid level control hole 104 on the side wall of the sleeve 102 can be in a flexible and adjustable form, for example, a slide rail mechanism can be used to flexibly adjust the height and size of the liquid level control hole 104. Figure 4a As shown, a first slide rail mechanism is used, including a first slide 111, a second slide 112, and a slide rail 110 that can be closely fitted with the first slide 111 and the second slide 112. The first slide 111 and the second slide 112 can slide on the slide rail 110. The slide rail 110 is provided with a hollow groove 130 (such as Figure 4c As shown in the figure, the liquid can flow inside and outside the sleeve 102 through the hollow groove 130 (of course, in the part of the hollow groove 130 blocked by the slide, the liquid will be blocked by the slide and cannot flow). By sliding the first slide 111 and the second slide 112 on the slide guide 110, a gap or opening (not necessarily a circular opening, but also a rectangular or other shape) can be retained in the middle of the two to serve as the liquid level control hole 104. Because in these embodiments, the liquid level control hole 104 is determined by the relative position of the first slide 111 and the second slide 112, the height and size of the liquid level control hole 104 can be determined by the position of the slide selected on the slide guide 110. Such a technical solution increases the flexibility of setting the position of the liquid level control hole 104. The user can set the position of the liquid level control hole 104 (i.e., the height, to adjust the degree of centrifugation) according to the specific needs of different experiments, and can decide whether to increase the area of ​​the liquid level control hole 104 according to the viscosity of the liquid contained in the filtered liquid 200 to facilitate the smooth flow of liquid therethrough.

[0054] In some specific embodiments of the present invention, Figure 4bAs shown, the liquid level control hole 104 is provided on the side wall of the sleeve 102, and the second slide rail mechanism can be used to achieve the height adjustment of the liquid level control hole 104. The above-mentioned second slide rail mechanism includes a third slide 113, and a slide rail 110 that is closely fitted with the third slide. The third slide 113 slides on the slide rail 110. The third slide 113 is provided with one or more openings (not necessarily circular openings, but also rectangular or other shapes) at appropriate positions as the liquid level control hole 104, and the slide rail 110 is provided with a hollow groove 130 that penetrates the side wall of the sleeve 102, and the liquid can pass through the hollow groove 130 (of course, the part of the hollow groove 130 blocked by the third slide 113, the liquid will be blocked by the third slide 113 and cannot flow). In these embodiments, the height of the liquid level control hole 104 can be determined by the position where the third slide 113 slides on the slide rail 110. This technical solution improves the flexibility of adjusting the position of the liquid level control hole 104. The user can select the position (i.e., height) of the liquid level control hole 104 according to the specific requirements of different experiments to adjust the degree of centrifugation. Figure 4c As shown, the third slide plate 113 should be prevented from being moved upward too much when sliding, which would cause the bottom of the third slide plate 113 to be higher than the bottom of the hollow groove 130, exposing the bottom of the hollow groove 130, allowing liquid to flow out of the hollow groove 130 (rather than the liquid level control hole 104), causing the liquid level control hole 104 to fail, etc.

[0055] The centrifugal assembly 100 disclosed in the present invention can adjust the liquid level of the filtered liquid 200 through the liquid level control hole 104, which can not only keep the filter filler 105 fully moist during the centrifugation process, but also can simply but effectively adjust the degree of centrifugation. Therefore, it has important uses in experiments such as low-abundance protein enrichment experiments and mycotoxin pretreatment solid phase extraction purification processes.

[0056] Specifically, when doing a low-abundance protein enrichment experiment, it is usually necessary to first use a filter filler 105 to enrich the low-abundance proteins on the filter filler 105 (that is, the filtered liquid 200 containing the low-abundance proteins is filtered through the filter filler 105), and then the low-abundance proteins are washed off from the filter filler 105 by a solvent. If the low-abundance proteins are over-centrifuged during the enrichment process of the filter filler 105, resulting in the drying of the filter filler 105, it is difficult for the low-abundance proteins to be washed off from the filter filler 105, which will affect the recovery rate of the experiment, so it is important to keep the filter filler 105 in a wet state. The centrifugal assembly 100 of the present invention can effectively solve this technical problem in the protein enrichment experiment of proteomics research - the liquid level of the protein solution after centrifugation can be controlled by adjusting the height of the liquid level control hole 104 (based on the principle of the communicating vessel, the height of the liquid level will not be lower than the height of the liquid level control hole 104), so that the protein solution level after centrifugation can be guaranteed to be still higher than the surface of the filter filler 105, and even the centrifugal degree of the protein solution can be effectively adjusted, which is conducive to realizing standardized centrifugal operation.

[0057] Similarly, when it is necessary to filter fungal toxins or certain pigments, it is also necessary to ensure that the filter filler 105 is in a moist state during the centrifugal filtration process to avoid difficulty in washing away and collecting the fungal toxins and pigments in subsequent experiments due to drying of the filter filler 105 .

[0058] The embodiments of the present invention are described above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned specific implementation modes, which are merely illustrative rather than restrictive. Under the guidance of the present invention, ordinary technicians in this field can also make many forms without departing from the scope of protection of the present invention and the claims, all of which are within the protection of the present invention.

Claims

1. A centrifugal assembly (100) capable of adjusting the centrifugal degree of filtered liquid, characterized in that: The invention comprises a filter tube (101), a sleeve (102) for placing the filter tube (101), and a fixing member (103) for fixing the sleeve (102) on a centrifuge tube (107); wherein an outlet (120) is provided at the bottom of the filter tube (101) to connect the filter tube (101) and the sleeve (102); and a liquid level control hole (104) is provided on the tube wall of the sleeve (102), wherein the liquid level control hole (104) penetrates the tube wall of the sleeve (102) to connect the sleeve (102) and the centrifuge tube (107); a first slide rail mechanism, the first slide rail mechanism comprising a first slide plate (111), a second slide plate (112) and a slide plate guide rail (110), the first slide plate (111) and the second slide plate (112) being able to slide on the slide plate guide rail (110), the slide plate guide rail (110) being provided with a hollow groove (130) penetrating the wall of the sleeve (102), and the liquid level control hole (104) being located between the first slide plate (111) and the second slide plate (112); or, a second slide rail mechanism, the second slide rail mechanism comprising a third slide plate (113) and a slide plate guide rail (110), the third slide plate (113) being provided with the liquid level control hole (104), and the slide plate guide rail (110) being provided with a hollow groove (130) penetrating the wall of the sleeve (102); It also includes: a filter filler (105) and a filter membrane (106), wherein the filter filler (105) is loaded in the filter tube (101); and the filter membrane (106) is placed at the bottom of the filter tube (101) to cover the outlet (120).

2. The centrifugal assembly (100) according to claim 1, characterized in that: The diameter of the sleeve (102) is greater than the diameter of the filter tube (101), and a protruding structure (124) is provided on the outer side of the tube wall of the filter tube (101) to stably clamp the filter tube (101) in the sleeve (102).

3. The centrifugal assembly (100) according to claim 1, characterized in that: The filter tube (101) and the sleeve (102) are of gun head type.

4. The centrifugal assembly (100) according to claim 1, characterized in that: The filter tube (101) and the sleeve (102) are cylindrical.

5. The centrifugal assembly (100) according to claim 1, characterized in that: The diameter of the liquid level control hole (104) is in the range of 0.1 mm to 0.5 mm.

6. The centrifugal assembly (100) according to claim 3, characterized in that: The vertical height range between the liquid level control hole (104) and the outlet (120) is 5 mm to 9 mm.

7. The centrifugal assembly (100) according to claim 4, characterized in that: The vertical height range between the liquid level control hole (104) and the outlet (120) is 10 mm to 14 mm.

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