A multi-channel loading arm

Abstract

The present invention relates to the technical field of liquid transfer arms, and discloses a multi-channel loading arm, including a loading module guide rail and a synchronous belt installed parallel to a frame and its inner wall, a loading module installed on the loading module guide rail and the synchronous belt, and the loading module including a loading module bracket, one side of the loading module bracket is fixed on a slider of the loading module guide rail, a loading module Z-direction drive motor and a Y-direction drive module are installed on the fixed side of the loading module bracket, and a loading module Z-direction sliding mechanism is installed on the other side, the Y-direction motion module is connected to the synchronous belt, the loading module Z-direction drive motor is connected to the loading module Z-direction sliding mechanism through a transmission mechanism, a loading module Z-direction sliding mechanism is installed on the loading module Z-direction sliding mechanism, and a loading pump is installed on the loading pump. A capacitance detection sheet and a pressure sensor are installed on the loading pump. A multi-channel loading arm provided by the present invention can realize non-equidistant loading of experimental samples and reagents, and has both capacitance sensing and pressure sensing liquid level detection functions to enhance versatility.

Description

Technical Field

[0001] The invention relates to the technical field of multi-channel sample loading arms, in particular to a multi-channel sample loading arm. Background Art

[0002] In the field of in vitro diagnostic medical devices, multi-channel loading arms are required for processes such as sample or reagent distribution. The spacing between the loading channels of existing multi-channel loading arms is fixed or adjustable at equal intervals, and they generally work simultaneously. Their flexibility is not high, especially for the distribution of reagents. Since the sizes of reagent bottles of different types and manufacturers are different, fixed-interval and adjustable equal-interval loading channels are difficult to meet their loading needs.

[0003] In addition, pressure surface detection is required before adding samples or dispensing reagents. Existing loading arms generally only have a single pressure-sensing liquid level detection function or a single capacitance-detection liquid level detection function. Since bubbles are easily generated during the pressure-sensing liquid level detection process, bubble explosions may cause contamination to experiments such as nucleic acid testing. Therefore, they cannot be used for experiments such as nucleic acid testing. Capacitance detection can only be used for tests where the target liquid is conductive. Both of these have certain limitations. Summary of the invention

[0004] The purpose of the present invention is to overcome the shortcomings of the prior art and provide a multi-channel loading arm, which can realize non-equidistant loading of experimental samples and reagents, and has both capacitive sensing and pressure sensing liquid level detection functions, thereby enhancing versatility.

[0005] The purpose of the present invention is achieved through the following technical solutions:

[0006] A multi-channel loading arm comprises a frame, a loading module guide rail and a synchronous belt are installed in parallel on the inner wall of one side of the frame, a plurality of loading modules are installed on the loading module guide rail and the synchronous belt, the loading module comprises a loading module bracket, one side of the loading module bracket is fixed on the slider of the loading module guide rail, the fixed side of the loading module bracket is installed with a loading module Z-direction driving motor and a Y-direction driving module, and the other side is installed with a loading module Z-direction sliding mechanism, the Y-direction motion module comprises a Y-direction motor seat, a Y-direction motor is installed on the Y-direction motor seat, a synchronous wheel is installed on the output shaft of the Y-direction motor, the gear teeth of the synchronous wheel are meshed with the belt teeth of the synchronous belt, and belt pressing wheels are installed on both sides of the synchronous wheel, the loading module Z-direction driving motor The machine is located above the Y-direction motion module, the Z-direction driving motor of the sample loading module is connected to the Z-direction sliding mechanism of the sample loading module through a transmission mechanism, the Z-direction sliding mechanism of the sample loading module is equipped with a sample loading pump, the sample loading pump comprises a pump body, the upper end of the pump body is equipped with a sample loading pump driving motor, the lower end is equipped with an adapter seat, the lower end of the adapter seat is equipped with an adapter, a capacitance detection piece is installed on the adapter, an insulating sleeve is installed between the capacitance detection piece and the adapter seat, a pressure sensor is installed on the side wall of the adapter seat, the sensing part of the pressure sensor is connected to the internal channel of the adapter seat, the capacitance detection piece and the pressure sensor are connected to the control board through a wire, and the adapter is made of conductive material.

[0007] In the above-mentioned multi-channel loading arm, each loading channel is controlled to work independently through the Y-axis driving module. When the number of samples or reagents is less than the number of loading channels, the matching loading channels can be assigned to work, and other loading channels do not work. During the loading process, the distance between the loading channels can be flexibly adjusted according to the distance between the sample tubes or reagent bottles, so that after the adapter takes out the needle, the loading needle can accurately enter the sample tube or reagent bottle to aspirate liquid. During the aspiration process, capacitive liquid level detection or pressure-sensitive liquid level detection can be flexibly selected according to the conductivity of the aspirated liquid and the applicable test conditions.

[0008] As an improvement to the present invention, a sample loading module guide rail, a synchronous belt and a sample loading module are also installed in the middle of the frame. The sample loading modules in the middle and on the sides are arranged in a centrally symmetrical manner and the axes of the adapters on each sample loading module are coplanar. Its functions are to increase the number of sample loading channels, reduce the types of adapter seats, and reduce manufacturing costs.

[0009] As a further improvement of the present invention, the Y-axis drive modules on adjacent loading modules are installed in reverse positions up and down, the number of synchronous belts on the loading module installation side is 2, and the adjacent Y-axis drive modules are respectively connected to the upper and lower synchronous belts, which function is to reduce the bending times and load of the synchronous belts and ensure the stability of the transmission.

[0010] As another improvement of the present invention, the inner arm on the other side of the frame is installed with a gripper module guide rail and a synchronous belt in parallel, and the gripper module is installed on the gripper module guide rail and the synchronous belt. The gripper module includes a gripper module bracket, one side of the gripper module bracket is fixed on the slider of the gripper module guide rail, the fixed side of the gripper module bracket is installed with the gripper module Z-direction drive motor and the Y-direction drive module, and the other side is installed with the gripper module Z-direction sliding mechanism, and the gripper mechanism is installed on the gripper module Z-direction sliding mechanism, and its function is to enable the loading arm to have the function of transferring reaction plates (such as microplates, deep well plates or PCR plates), thereby improving the utilization rate of the loading arm.

[0011] As a further improvement of the present invention, a needle-removing mechanism is installed on the sample adding pump, and its function is to realize automatic needle-removal of the sample adding needle and save platform space.

[0012] As an improvement to the needle-removing mechanism in the present invention, the sample pump driving motor is a through-shaft motor, and the needle-removing mechanism includes a push block installed on the output shaft of the sample pump driving motor and a push rod passing through the pump body and the adapter seat, a push rod limit block is installed on the upper end of the push rod, and a syringe removal cylinder is installed on the lower end, one end of the syringe removal cylinder is sleeved on the adapter, and a tension spring is installed on the push rod, and the two free ends of the tension spring are respectively fixed on the syringe removal cylinder and the adapter seat.

[0013] As an improvement to the present invention, the number of the sample adding modules is 2 to 4, and the function of the sample adding modules is to concentrate the sample adding modules on one side of the frame, thereby freeing up space for installing the gripper module on the other side.

[0014] As another improvement to the present invention, the number of the sample adding modules is 5 to 8, and their function is to install the sample adding modules in a centrally symmetrical manner in the middle and one side of the frame, thereby reducing the types of adapter seats and syringes and lowering manufacturing costs.

[0015] In combination with the above technical solutions, compared with the prior art, the multi-channel sample loading arm provided by the present invention has the following beneficial effects:

[0016] The multi-channel loading arm provided by the present invention is equipped with a Y-axis driving module on each loading module for individual driving, so that the distance between the loading needles can be flexibly adjusted during liquid distribution to adapt to different sample tube spacings and reagent bottle spacings, thereby expanding the loading range.

[0017] The multi-channel loading arm provided by the present invention has both capacitive liquid level detection function and pressure sensing liquid level detection function, and can customize the liquid level detection method according to experimental requirements, thereby expanding the scope of use and ensuring the sensitivity of liquid level detection.

[0018] The multi-channel loading arm provided by the present invention can automatically remove the needle after completing liquid distribution, without setting a special needle removal position on the experimental platform, thus saving platform space; installing a gripper module in the loading arm increases the reaction plate transfer function and improves the utilization rate of the loading arm. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic structural diagram of a multi-channel loading arm described in the present invention.

[0020] Figure 2 The figure is a schematic diagram of the installation position of the guide rail of the sample loading module according to the present invention.

[0021] Figure 3 This is a schematic structural diagram of a multi-channel loading arm of the present invention when the number of loading channels is eight.

[0022] Figure 4 It is a structural schematic diagram of the sample adding module described in the present invention.

[0023] Figure 5 This is a schematic diagram of the installation position of the pressure sensor described in the present invention.

[0024] Figure 6 It is a schematic diagram of the structure of the sample adding pump described in the present invention.

[0025] Figure 7 It is a schematic structural diagram of the Y-direction driving module of the present invention.

[0026] Figure 8 This is a schematic diagram of the installation position of the gripper module described in the present invention.

[0027] Fig. 9 It is a structural schematic diagram of the gripper module described in the present invention.

[0028] Fig.10 This is a schematic diagram of the installation position of the sample adding module described in the present invention.

[0029] Fig.11 Schematic diagram of the structure of the adapter seat and the syringe for two channels.

[0030] Fig.12 Schematic diagram of the structure of the adapter seat and the syringe for three channels.

[0031] Fig.13 Schematic diagram of the structure of the adapter seat and the syringe for four channels.

[0032] Fig.14 Schematic diagram of the structure of the adapter seat and the syringe for eight channels.

[0033] Among them, 1-frame, 2-gripper module guide rail, 3-gripper module, 31-gripper module bracket, 32-gripper module Z-direction drive motor, 33-gripper module Z-direction sliding mechanism, 34-gripper mechanism, 4-synchronous belt, 5-sample loading module guide rail, 6-sample loading module, 61-sample loading module bracket, 62-sample loading module Z-direction sliding mechanism, 63-sample loading module Z-direction drive motor, 64-sample loading pump, 641-sample loading pump drive motor, 642-pump body, 643, 643a, 643a′, 643 b, 643b′, 643c, 643c′, 643d, 643d′-adapter seat, 644-needle removing mechanism, 6441-push block, 6442-push rod limit block, 6443-push rod, 6444, 6444a, 6444a′, 6444b′, 6444c, 6444c′, 6444d, 6444d′-needle removing cylinder, 6445-tension spring, 7-Y-axis drive module, 71-Y-axis motor seat, 72-Y-axis motor, 73-synchronizing wheel, 74-pressure wheel. DETAILED DESCRIPTION

[0034] To explain the technical features and achieved purposes and effects of the present invention in detail, further description is given below in conjunction with the accompanying drawings:

[0035] like Figure 1-10As shown, a multi-channel loading arm comprises a frame 1, a loading module guide rail 5 and a synchronous belt 4 are installed in parallel on the inner wall of one side of the frame 1, a plurality of loading modules 6 are installed on the loading module guide rail 5 and the synchronous belt 4, the loading module 6 comprises a loading module bracket 61, one side of the loading module bracket 61 is fixed on the slider of the loading module guide rail 5, a loading module Z-direction drive motor 63 and a Y-direction drive module 7 are installed on the fixed side of the loading module bracket 61, and a loading module Z-direction sliding mechanism 62 is installed on the other side, the Y-direction motion module 7 comprises a Y-direction motor seat 71, a Y-direction motor 72 is installed on the Y-direction motor seat 71, a synchronous wheel 73 is installed on the output shaft of the Y-direction motor 72, the gear teeth of the synchronous wheel 73 are meshed with the belt teeth of the synchronous belt 4, and belt pressing wheels 74 are installed on both sides of the synchronous wheel, the loading module Z-direction drive motor 63 is located above the Y-direction motion module 7, The Z-direction driving motor 63 of the loading module is connected to the Z-direction sliding mechanism 62 of the loading module through a transmission mechanism, and a loading pump 64 is installed on the Z-direction sliding mechanism 62 of the loading module, and the loading pump 64 includes a pump body 642, and a loading pump driving motor 641 is installed on the upper end of the pump body 642, and an adapter seat 643 is installed on the lower end, and an adapter 647 is installed on the lower end of the adapter seat 643, and a capacitance detection piece 648 is installed on the adapter 647, and an insulating sleeve 649 is installed between the capacitance detection piece 648 and the adapter seat 643, and a pressure sensor 645 is installed on the side wall of the adapter seat 643, and the sensing part of the pressure sensor 645 is connected to the internal channel of the adapter seat 643, and the capacitance detection piece 648 and the pressure sensor 645 are connected to the control board 646 through wires, and the adapter 647 is made of conductive material.

[0036] Preferably, the Y-direction driving modules 7 on adjacent loading modules 6 are installed in reverse positions up and down, the number of the synchronous belts 4 on the installation side of the loading module 6 is 2, and the adjacent Y-direction driving modules 7 are connected to the upper and lower synchronous belts 4 respectively.

[0037] Preferably, a needle-removing mechanism is installed on the sample adding pump.

[0038] Preferably, the sample pump driving motor 641 is a through-axis motor, and the needle-removing mechanism includes a push block 6441 installed on the output shaft of the sample pump driving motor 641 and a push rod 6443 that passes through the pump body 642 and the adapter seat 643, a push rod limit block 6442 is installed on the upper end of the push rod 6443, and a needle-removing cylinder 6444 is installed on the lower end, one end of the needle-removing cylinder 6444 is sleeved on the adapter 647, and a tension spring 6445 is installed on the push rod 6443, and the two free ends of the tension spring 6445 are respectively fixed on the needle-removing cylinder 6444 and the adapter seat 643.

[0039] Preferably, the number of the sample loading modules 6 is 2 to 8. When the number of the sample loading modules 6 is 5 to 8, the sample loading module guide rail 5, the synchronous belt 4 and the sample loading module 6 are also installed in the middle of the frame 1. The sample loading modules 6 in the middle and on the side are arranged in a central symmetric manner and the axes of the adapters 647 on each sample loading module 6 are coplanar. The inner arm on the other side of the frame 1 is parallelly installed with a gripper module guide rail 2 and a synchronous belt 4. The gripper module 3 is installed on the gripper module guide rail 2 and the synchronous belt 4. The gripper module 3 includes a gripper module bracket 31. One side of the gripper module bracket 31 is fixed on the slider of the gripper module guide rail 2. The gripper module Z-direction drive motor 32 and the Y-direction drive module 7 are installed on the fixed side of the gripper module bracket 31, and the gripper module Z-direction sliding mechanism 33 is installed on the other side. The gripper mechanism 34 is installed on the gripper module Z-direction sliding mechanism 33.

[0040] like Fig.11 As shown, in one of the embodiments, there are two sample loading channels, and the lower ends of the pump bodies 642 on the left and right sample loading modules 6 are respectively installed with adapter seats 643a and 643a′, and the adapter 647 is respectively installed with removal syringes 6444a and 6444a′, and the structures of the adapter seats 643a and 643a′ are symmetrical, and the structures of the removal syringes 6444a and 6444a′ are symmetrical.

[0041] like Fig.12 As shown, in one of the embodiments, there are three sample loading channels, and a sample loading module 6 on the left side is added to the frame 1 based on the above embodiment, and an adapter seat 643b is installed at the lower end of the pump body 642 on the left sample loading module 6, and a syringe 6444b is installed on the adapter 647.

[0042] like Fig.13 As shown, in one of the embodiments, there are four sample loading channels, and a sample loading module 6 on the right side is added to the frame 1 based on the above embodiment, and an adapter seat 643b′ is installed at the lower end of the pump body 642 on the right sample loading module 6, and a syringe 6444b′ is installed on the adapter 647.

[0043] like Fig.14 As shown, in one of the embodiments, there are 8 sample loading channels, and the sample loading modules 6 are respectively installed on the side and the middle of the frame 1, and the four sample loading modules 6 on both sides are installed in a centrally symmetrical manner, and the lower ends of the pump bodies 642 on the four sample loading modules 6 on each side are respectively installed with adapter seats 643c, adapter seats 643c′, adapter seats 643d, and adapter seats 643d′, and the adapter 647 is respectively installed with removal syringes 6444c, removal syringes 6444c′, removal syringes 6444d, and removal syringes 6444d′.

[0044] The multi-channel sample loading arm provided in the above embodiment has the following specific implementation process:

[0045] Before the start of the sample addition, set the liquid level detection method according to the nature of the experiment and the sample situation. You can select capacitive liquid level detection alone or pressure sensing liquid level detection alone, or both capacitive detection and pressure sensing. After completing the liquid level detection method setting, set the sample addition interval during the sample addition process according to the interval between the sample tubes and / or reagent bottles.

[0046] After completing the above settings, the loading arm takes the needle, and then adjusts the spacing between the loading modules 6 according to the preset loading spacing, so that the spacing between the loading needles 65 matches the spacing between the sample tubes or reagent bottles. During the spacing adjustment process, the Y-axis driving motor 72 on each loading module 6 drives the synchronous pulley 73 to rotate, so that the loading module 6 slides along the synchronous belt 4 and the loading module guide rail 5 until it reaches the specified position.

[0047] When the capacitive liquid level detection method is selected, the sample needle 65 used is conductive. When the tip of the sample needle 65 touches the liquid surface, a conductive state is formed between the sample needle 65, the adapter 647, the capacitive detection sheet 648 and the control board 646. The control board 646 receives a signal that the liquid level has been detected, and the sample arm records the initial position data in order to calculate the liquid aspiration depth and ensure the accuracy of the aspirated amount.

[0048] When the pressure-sensing liquid level detection mode is selected, during the downward sliding of the sampling module Z-direction sliding mechanism 62, the sampling pump driving motor 641 rotates to make the piston in the pump body 642 move downward, and the needle tip of the sampling needle 65 slowly exhausts air outwards. The pressure sensor 645 detects the air pressure in the adapter seat 643. When the needle tip of the sampling needle 65 touches the liquid surface, the air pressure in the adapter seat 643 changes due to the resistance of the liquid surface. The pressure sensor 645 feeds back a signal to the control board 646. The control board 646 obtains the detected liquid level signal and records the initial liquid level data in order to calculate the liquid aspiration depth to ensure the accuracy of the liquid aspiration amount.

[0049] When both capacitive liquid level detection and pressure-sensitive liquid level detection are selected, when one of the detection methods detects the liquid level, the other detection method stops.

[0050] After the liquid is absorbed, the spacing between the sample injection modules 6 is adjusted according to the hole spacing on the reaction plate (such as a microplate, a deep well plate or a PCR plate) so that the sample injection needle 65 can accurately inject the sample or reagent into the corresponding hole position.

[0051] After completing the sample loading process, the sample loading arm moves to the needle removal position, and the sample loading pump driving motor 641 drives the piston and the push block 6441 in the pump body 642 to move downward at the same time, so that the residual sample or reagent is discharged from the sample loading needle, and then the sample loading pump driving motor 641 continues to rotate to make the push block 6441 push the push rod limit block 6442, so that the lower end of the push rod 6443 pushes the syringe barrel 6444 to move downward and push the sample loading needle 65 away from the adapter 647, thereby completing the automatic needle removal.

[0052] When a gripper module 3 is installed on the other side of the frame 1, after the sample addition is completed, the reaction plate can be transferred by the gripper module 3, and the gripping position of the gripper module 3 is adjusted by the gripper module Z-direction drive motor 32 and the Y-direction drive module 7 installed on the gripper module bracket 31.

[0053] It can be seen from the above embodiments and implementation steps that the multi-channel loading arm provided by the present invention can arbitrarily set the spacing between the loading needles 65 according to the size and spacing of the sample tubes and reagent bottles and the spacing of the holes on the reaction plate, so that the loading needles 65 can accurately enter the sample tubes and reagent bottles during the process of aspirating samples and reagents. During the loading process, the loading needles 65 can accurately load samples into the reaction holes on the reaction plate, and it has strong flexibility.

[0054] The multi-channel sample loading arm provided by the present invention can fully match the experimental characteristics with the liquid level detection mode through customized settings of the liquid level detection mode, thereby avoiding the influence of the liquid level detection mode on the experimental results and having a wider application range. The use of two liquid level detection modes at the same time can ensure the detection sensitivity, thereby making the liquid aspiration result more accurate.

[0055] The multi-channel loading arm provided by the present invention can automatically remove the needle after loading is completed, and no external needle removal structure is required. The automatic needle removal can be completed by driving the motor 641 through the loading pump, saving the installation space of the needle removal mechanism.

[0056] The applicant declares that the above-described embodiments only express the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above-described embodiments, and the above-described embodiments and the specification only describe the principles of the present invention. For those skilled in the art, various changes and improvements can be made without departing from the concept and scope of the present invention, and these changes and improvements all fall within the scope of the present invention to be protected.

[0057] The present invention is not limited to the above-mentioned embodiments. Any embodiments that use structures and methods similar to those of the present invention to achieve the purpose of the present invention are within the protection scope of the present invention.

Claims

1. A multi-channel loading arm, characterized in that: The invention comprises a frame (1), wherein a sample loading module guide rail (5) and a synchronous belt (4) are installed in parallel on the inner wall of one side of the frame (1), and a plurality of sample loading modules (6) are installed on the sample loading module guide rail (5) and the synchronous belt (4), wherein the sample loading module (6) comprises a sample loading module bracket (61), wherein one side of the sample loading module bracket (61) is fixed on a slider of the sample loading module guide rail (5), and a sample loading module Z-direction drive motor (63) and a Y-direction drive module (7) are installed on the fixed side of the sample loading module bracket (61), and a sample loading module Z-direction sliding mechanism (62) is installed on the other side, wherein the Y-direction drive module (7) comprises a Y-direction motor seat (71), and a Y-direction motor (7) is installed on the Y-direction motor seat (71). 2), a synchronous wheel (73) is installed on the output shaft of the Y-direction motor (72), the gear teeth of the synchronous wheel (73) mesh with the belt teeth of the synchronous belt (4), and belt pressing wheels (74) are installed on both sides of the synchronous wheel. The Z-direction driving motor (63) of the sample loading module is located above the Y-direction driving module (7), and the Z-direction driving motor (63) of the sample loading module is connected to the Z-direction sliding mechanism (62) of the sample loading module through a transmission mechanism. The Z-direction sliding mechanism (62) of the sample loading module is installed with a sample loading pump (64), and the sample loading pump (64) includes a pump body (642), the upper end of the pump body (642) is installed with a sample loading pump driving motor (641), and the lower end of the pump body (642) is installed with an adapter seat (643, 643a) , 643a′, 643b, 643b′, 643c, 643c′, 643d, 643d′), an adapter (647) is installed at the lower end of the adapter seat (643, 643a, 643a′, 643b, 643b′, 643c, 643c′, 643d, 643d′), a capacitance detection sheet (648) is installed on the adapter (647), an insulating sleeve (649) is installed between the capacitance detection sheet (648) and the adapter seat (643, 643a, 643a′, 643b, 643b′, 643c, 643c′, 643d, 643d′), and the adapter seat (643, 643a A pressure sensor (645) is installed on the side wall of the adapter seat (643, 643a', 643b, 643b', 643c, 643c', 643d, 643d'), and the sensing part of the pressure sensor (645) is aligned with the adapter seat (643, 643a , 643a′, 643b, 643b′, 643c, 643c′, 643d, 643d′) are connected to each other through internal channels, the capacitance detection sheet (648) and the pressure sensor (645) are connected to the control board (646) through wires, the middle of the frame (1) is also equipped with a sample loading module guide rail (5), a synchronous belt (4) and a sample loading module (6), the sample loading modules (6) in the middle and on the side are arranged in a central symmetric manner, and the axes of the adapters (647) on each sample loading module (6) are coplanar, the Y-direction drive modules (7) on adjacent sample loading modules (6) are installed in reverse positions in the upper and lower positions, and the number of synchronous belts (4) on the installation side of the sample loading module (6) is 2,Adjacent Y-direction drive modules (7) are respectively connected to the upper and lower synchronous belts (4); the inner arm on the other side of the frame (1) is parallelly mounted with a gripper module guide rail (2) and a synchronous belt (4); the gripper module (3) is mounted on the gripper module guide rail (2) and the synchronous belt (4); the gripper module (3) comprises a gripper module bracket (31); one side of the gripper module bracket (31) is fixed on a slider of the gripper module guide rail (2); the gripper module Z-direction drive motor (32) and the Y-direction drive module (7) are mounted on the fixed side of the gripper module bracket (31); the gripper module Z-direction sliding mechanism (33) is mounted on the other side; the gripper mechanism (34) is mounted on the gripper module Z-direction sliding mechanism (33).

2. A multi-channel loading arm according to claim 1, characterized in that: The sample adding pump is provided with a needle removing mechanism (644).

3. A multi-channel loading arm according to claim 2, characterized in that: The sample pump driving motor (641) is a through-axis motor, and the needle-removing mechanism comprises a push block (6441) mounted on the output shaft of the sample pump driving motor (641) and a push rod (6443) that penetrates the pump body (642) and the adapter seat (643, 643a, 643a', 643b, 643b', 643c, 643c', 643d, 643d'), the push rod limiting block (6442) is mounted on the upper end of the push rod (6443), and a needle-removing cylinder (6444, 6444a, 6444a', 6444b', 6444c, 6444c', 6444d, 6444d') is mounted on the lower end, and the needle-removing cylinder (6444, 6444a, 6444a', 6444b', 6444c, 6444c', 6444d, 6444d') is mounted on the lower end. One end of the push rod (6443) is sleeved on the adapter (647), and a tension spring (6445) is installed on the push rod (6443), and two free ends of the tension spring (6445) are respectively fixed on the needle cylinder (6444, 6444a, 6444a', 6444b', 6444c, 6444c', 6444d, 6444d') and the adapter seat (643, 643a, 643a', 643b, 643b', 643c, 643c', 643d, 643d').

4. A multi-channel loading arm according to claim 1, characterized in that: The number of the sample adding modules (6) is 2 to 4.

5. The multi-channel loading arm according to claim 1, characterized in that: The number of the sample adding modules (6) is 5 to 8.

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