Pest repellent composition

Abstract

The pest repellent composition of the present invention contains the following components (A) and (B): (A) a non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a type B rotational viscometer: 13% by mass or more and 99.95% by mass or less; (B) a specific fragrance: 0.05% by mass or more and 3.5% by mass or less.

Description

Technical Field

[0001] This invention relates to an insect repellent composition. Background Technology

[0002] Flying pests such as mosquitoes and flies can transmit pathogens to humans and other animals, becoming a major factor in causing infections or dermatitis. In particular, some mosquitoes transmit pathogens such as dengue fever, Zika fever, yellow fever, encephalitis, and malaria, making them highly harmful insects from a hygienic perspective.

[0003] To protect themselves from these flying pests, people have traditionally used methods such as dispersing insecticides or applying repellents to their skin. A typical repellent is DEET (N,N-diethyltoluamide).

[0004] Mosquitoes and other pests possess chemosensory systems, such as thermoreceptors to sense animal body temperature, olfactory receptors to sense volatile substances like body odor, and carbon dioxide receptors to sense carbon dioxide. These systems allow them to detect animals. DEET disables the cognitive senses of these pests by distorting their chemosensory systems, thereby repelling them.

[0005] However, DEET has an unpleasant odor, and a certain amount must be used to achieve its full and lasting repellent effect. Furthermore, it is known to cause allergies or rough skin, and there are limitations on the amount or frequency of use for young children or people with sensitive skin.

[0006] Therefore, some studies utilize natural essential oils as repellent ingredients. Citronella oil, lemon eucalyptus oil, lemongrass oil, orange peel oil, cinnamon oil, and other natural essential oils are also used in candles or scented lotions and are generally considered safe for human use. However, their repellent effect on pests is not long-lasting, raising questions about their practicality.

[0007] In addition, various proposals have been put forward regarding repellents or repellent compositions for pests.

[0008] For example, Patent Document 1 describes the use of insect repellents such as DEET in skin protectants containing fluorinated polyether co-modified silicone and ultraviolet defense components.

[0009] Furthermore, the use of fragrance components as repellents has also been proposed. Patent Document 2 discloses an insect repellent that uses fragrance components such as octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one to act on the heat receptors of blood-sucking insects and inhibit their heat response. Patent Document 3 discloses that fragrance components such as 2-methoxy-4-propylphenol inhibit the neural response of insects to carbon dioxide stimulation and can be used for insect repellency.

[0010] [Existing technical documents]

[0011] [Patent Literature]

[0012] Patent Document 1: Japanese Patent Application Publication No. 8-59447

[0013] Patent Document 2: Japanese Patent Application Publication No. 2016-172715

[0014] Patent Document 3: Japanese Patent Application Publication No. 2016-164153 Summary of the Invention

[0015] The present invention provides the following [1] to [7].

[0016] [1] A pest repellent composition or a pest dwelling inhibition composition, comprising the following components (A) and (B),

[0017] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass or more and 99.95% by mass.

[0018] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0019] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0020] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0021] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0022] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0023] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0024] (B6)2-ethyl phenylacetate

[0025] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0026] (B8) Dimethylphenethyl methanol acetate,

[0027] (B9) Methyl anthranilate.

[0028] [2] A water-in-oil type mosquito repellent composition or mosquito retention inhibitory composition, wherein the composition contains the following components (A) to (C), and the content of the insect repellent other than component (A) and component (B) is 15% by mass or less.

[0029] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0030] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0031] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0032] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0033] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0034] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0035] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0036] (B6)2-ethyl phenylacetate

[0037] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0038] (B8) Dimethylphenethyl methanol acetate,

[0039] (B9) Methyl anthranilate;

[0040] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0041] [3] A water-in-oil type mosquito repellent composition or mosquito retention inhibition composition, wherein the composition contains the following components (A) to (C), the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400, and the content of pest repellent other than component (A) and component (B) is 15% by mass or less.

[0042] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0043] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0044] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0045] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0046] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0047] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0048] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0049] (B6)2-ethyl phenylacetate

[0050] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0051] (B8) Dimethylphenethyl methanol acetate,

[0052] (B9) Methyl anthranilate;

[0053] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0054] [4] A water-in-oil type mosquito repellent composition or mosquito retention inhibitory composition, wherein the composition contains the following components (A) to (C), the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400, and the content of pest repellent other than component (A) and component (B) is 15% by mass or less.

[0055] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0056] (B) One or more fragrances selected from octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctaldehyde: 0.05% by mass to 3.5% by mass;

[0057] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0058] [5] A water-in-oil type mosquito repellent composition or mosquito retention inhibitory composition, wherein the composition contains the following components (A) to (D), the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400, and the content of pest repellent other than component (A) and component (B) is 15% by mass or less.

[0059] (A) One or more non-volatile liquid oily components selected from silicone oil, ester oil and hydrocarbon oil, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% to 50% by mass.

[0060] (B) One or more fragrances selected from octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctaldehyde: 0.05% by mass to 3.5% by mass;

[0061] (C) Water: ≥35% by mass and ≤86.95% by mass;

[0062] (D) Tackifier: 0.05% by mass or more, 3% by mass or less.

[0063] [6] A method for repelling pests, wherein a composition of any one of [1] to [5] is applied to the surface of human skin.

[0064] [7] A method for inhibiting the dwelling of pests, wherein the pest is prevented from dwelling on human skin by attaching the composition of any one of [1] to [5] to the limbs of the pest. Detailed Implementation

[0065] [Insect repellent composition, insect dwell-inhibiting composition]

[0066] The pest repellent composition and pest retention inhibition composition of the present invention (hereinafter collectively referred to as "the compositions of the present invention") are compositions containing the following ingredients (A) and (B).

[0067] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass or more and 99.95% by mass.

[0068] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0069] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0070] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0071] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0072] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0073] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0074] (B6)2-ethyl phenylacetate

[0075] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0076] (B8) Dimethylphenethyl methanol acetate,

[0077] (B9) Methyl anthranilate.

[0078] The compounds (B1) to (B9) specified as ingredients (B) are known compounds used as fragrances. For example, all fragrances are disclosed in "Synthetic Fragrance Chemistry and Commercial Knowledge (Revised and Expanded Edition)" by Genichi Into, published by Chemical Industry Daily Press in 2005 (ISBN 4-87326-460-X).

[0079] The composition of the present invention contains specific amounts of component (A) and component (B), exhibiting excellent and sustained repellent effect against pests, especially flying pests, with less strong odor derived from the repellent fragrance, making it suitable for skin application as both an insect repellent composition and a pest retention inhibition composition. In addition to component (A), the composition of the present invention further contains specific amounts of component (B), and it is believed that by applying component (A) and component (B) together to the limbs of flying pests, the strong odor derived from component (B) can be reduced while simultaneously achieving excellent and sustained repellent effect.

[0080] Regarding dermal insect repellents, there is a desire for safety and minimal odor, resulting in excellent initial and sustained repellency. However, the current situation is that the main available insect repellents do not adequately meet these requirements.

[0081] As described above, existing pest repellents such as DEET described in Patent Document 1 have unpleasant odors and also pose safety concerns for humans. Therefore, there is a need for repellents that can be used more safely by young children or people with sensitive skin.

[0082] Patent documents 2 and 3 describe repellents that use compounds known as fragrance components. While increasing the content of the fragrance component can predict an improvement in the duration of the repellency, on the other hand, if the content of the fragrance component is too high, it may cause skin problems or make the repellent unusable due to an overly strong odor.

[0083] Currently, no composition has been found that offers excellent and long-lasting pest repellency, is safe, suppresses strong odors originating from the repellent ingredients, and is suitable for skin application.

[0084] The objective of this invention is to provide an insect repellent composition that is safe, provides excellent and sustained repellency against pests, especially flying pests, and suppresses strong odors derived from repellent fragrances, and is suitable for skin application.

[0085] Through specialized research, the inventors discovered that a non-volatile liquid oily component with specific surface tension and viscosity is effective in repelling pests such as mosquitoes. Furthermore, they found that certain fragrances also have a repellent effect, but a strong odor can be problematic in maintaining this effect. Therefore, by setting the fragrance content to a level that does not cause an odor problem and combining it with a non-volatile liquid oily component with specific surface tension and viscosity, they found that not only was a strong odor from the fragrance suppressed, but the repellent effect was unexpectedly prolonged. In other words, they discovered that an insect repellent composition containing a specific amount of a non-volatile liquid oily component with specific surface tension and viscosity, and a specific fragrance component, can solve the aforementioned problems.

[0086] According to the present invention, a pest repellent composition that has excellent and sustained repellent effect on pests, especially flying pests, is safe, and suppresses strong odors derived from repellent fragrances, and is suitable for skin application can be provided; a pest retention inhibition composition; a pest repellent method; and a pest retention inhibition method.

[0087] In this invention, the term "insect repellency effect" refers to the fact that even if insects come into contact with the target object, they will not stay and will immediately leave. The composition of this invention is equivalent to a contact repellency composition. That is, the insect repellency effect of this invention is different from that of repellents or insecticides that achieve repellency through non-contact with the target object, such as formulations that prevent insects from approaching the target object or formulations that prevent insects from approaching the target object, or insecticides that have insecticidal power and repel insects.

[0088] The compositions of this invention repel pests by immediately removing them from the surface even when they land on objects coated or covered with the compositions. Specifically, they exhibit the following retention inhibition effect: after landing on the skin of humans or other animals, mosquitoes and other pests are prevented from lingering in a specific area of ​​the skin for approximately the time required to insert a stinger, specifically more than one second. This effect is based on a previously unknown pest repellency principle and is relatively safe, without side effects such as rough skin. Therefore, the compositions of this invention can be used as pest retention inhibition compositions.

[0089] In this invention, the term "persistent repellency effect against pests" means that after the composition of this invention is applied to an object, the repellency effect remains effective even after a period of time. Furthermore, in the following description, the persistent repellency effect of this invention, especially against flying pests, will be briefly referred to as "persistent repellency effect".

[0090] The composition of the present invention contains one or more non-volatile liquid oily components selected from (a) silicone oil, (b) ester oil, (c) ether oil, (d) hydrocarbon oil, (e) aliphatic alcohol, and (f) polyol as component (A), having a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a type B rotational viscometer. By containing component (A), it exhibits excellent and sustained repellent effect against pests, especially flying pests. The reason for this is not yet determined, but it is believed to be due to the following.

[0091] The inventors have discovered that flying pests such as mosquitoes possess the following characteristics: to avoid the gravitational pull generated by the landing surface when their limbs are wet, they will avoid leaving their limbs on damp surfaces. Since the limbs of flying pests such as mosquitoes are hydrophobic, a liquid oily component with a surface tension of less than 40 mN / m at 25°C will have a high affinity for the limbs. Furthermore, if the liquid oily component has a viscosity of less than 400 mPa·s, the contact area between the liquid oily component and the limbs will increase significantly within a short period when the limbs come into contact with it. Therefore, it is believed that if a flying pest lands on a surface coated or adhered to with component (A), its limbs will become wet, and it will avoid the gravitational pull generated by the landing surface, flying away instead of remaining at the landing site.

[0092] Furthermore, in this invention, "landing" refers to a contact time of less than 1 second between a flying pest such as a mosquito and the target object. Also, in this invention, "staying" refers to a continuous contact time of more than 1 second between a flying pest such as a mosquito and the target object.

[0093] Furthermore, the composition of the present invention further contains a specific amount of the following component (B) in addition to component (A). It is believed that by applying component (A) and component (B) together to the limbs of flying pests, not only can the strong odor originating from component (B) be reduced, but also an excellent and sustained repellent effect can be achieved.

[0094] <Ingredient (A): Non-volatile liquid oily component>

[0095] The composition of the present invention contains component (A), which is a non-volatile liquid oily component selected from (a) silicone oil, (b) ester oil, (c) ether oil, (d) hydrocarbon oil, (e) aliphatic alcohol, and (f) polyol, having a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a type B rotational viscometer. In addition to component (A), the composition of the present invention further incorporates component (B), thereby suppressing the substrate odor present in component (A), suppressing the necessary volatilization of component (B), and allowing component (B) to be applied together with component (A) to the limbs of flying pests, achieving excellent repellency duration.

[0096] From the viewpoint that component (A) is easy to apply to the skin and enhances the lasting effect of repellency, it is preferably a non-volatile oil that is liquid at 20°C, more preferably at 15°C, and even more preferably at 10°C.

[0097] Furthermore, the term "liquid" in "liquid oily component" refers to the situation where it is determined to be a liquid according to the liquid-solid determination test based on the American Society for Testing and Materials standard "ASTM D4359-90: Standard Test Method for Determining Whether a Material is a Liquid or Solid".

[0098] From the viewpoint of enhancing the sustained repellency effect against pests, component (A) is preferably a poorly water-soluble or non-water-soluble component. Specifically, the amount of component (A) that can be dissolved in 100g of water at 20°C is preferably 1g or less, more preferably 0.5g or less, more preferably 0.1g or less, and even more preferably substantially 0g.

[0099] The liquid oily component (A) used in this invention is a non-volatile liquid oily component from the viewpoint of enhancing the long-lasting repellent effect. Here, the term "non-volatile liquid oily component" in this invention refers to a component with a volatility of 50% or less after drying at 1 atmosphere, 25°C, and 60 minutes; preferably, it refers to a component with a volatility of 50% or less after drying at 1 atmosphere, 25°C, and 120 minutes. The volatility is evaluated according to the German testing standard DIN53249, specifically according to steps 1 to 4 below.

[0100] 1. Measure the weight (P(g)) of a circular filter paper with a diameter of 150 mm.

[0101] 2. Using a pipette, drop 0.3 g of component (A) onto a round filter paper, and immediately measure the weight of the filter paper (W0(g)).

[0102] 3. Under airtight conditions, at 25°C, the weight of the filter paper is determined by a weight measurement with an accuracy of approximately 0.001g at 5-minute intervals. The weight of the filter paper measured 60 minutes after the measurement in step 2 is designated as W. 60 (g)

[0103] 4. The formula {((W0-P)-(W)} will be used to calculate the result. 60 The value derived from -P)) / (W0-P)}×100 is used as the volatile rate (%).

[0104] The lower the evaporation rate, the longer the liquid oily components remain on the skin when applied, thus resulting in a higher and longer-lasting repellent effect.

[0105] When using two or more liquid oily components, the volatile rate of the so-called non-volatile liquid oily component refers to the volatile rate of the mixture of two or more liquid oily components. Therefore, as long as the volatile rate of the mixture is within the above range, liquid oily components with a volatile rate of more than 50% after drying at 1 atmosphere and 25°C for 60 minutes can also be used in combination.

[0106] Regarding the surface tension of component (A) at 25°C, from the viewpoint of availability, it is preferably 15 mN / m or more, more preferably 17 mN / m or more, and from the viewpoint of improving the duration of the repellency effect, it is 40 mN / m or less, preferably 30 mN / m or less, more preferably 28 mN / m or less, even more preferably 25 mN / m or less, even more preferably 23 mN / m or less, and even more preferably 21 mN / m or less. Furthermore, even if its surface tension at 25°C exceeds 40 mN / m, if the surface tension can be reduced by mixing it with other liquid oily components, a duration of the repellency effect will still be achieved.

[0107] Regarding the viscosity of component (A) at 23°C, measured using a type B rotational viscometer, it is preferably 1 mPa·s or more from the viewpoint of suppressing volatility and improving the duration of repellency, and preferably 400 mPa·s or less from the viewpoint of improving the duration of repellency, more preferably 300 mPa·s or less, more preferably 210 mPa·s or less, further preferably 100 mPa·s or less, further more preferably 60 mPa·s or less, further more preferably 40 mPa·s or less, and further more preferably 30 mPa·s or less. Furthermore, when using two or more liquid oily components with different viscosities, the viscosity refers to the viscosity of the mixture of these liquid oily components.

[0108] The surface tension and viscosity of component (A) were determined by the methods described in the examples.

[0109] (a) Silicone oil

[0110] From the viewpoint of enhancing the lasting effect of repellency, the silicone oil is preferably selected from one or more of dimethyl polysiloxane, dimethiconol (dimethyl polysiloxane with hydroxyl groups at the end), methylphenyl polysiloxane, and modified silicone.

[0111] Examples of modified silicones include: amino-modified silicones (dimethyl polysiloxanes containing amino groups), polyether-modified silicones, glycerol-modified silicones, amino derivative polysiloxanes, carboxyl-modified silicones, fatty acid-modified silicones, alcohol-modified silicones, aliphatic alcohol-modified silicones, epoxy-modified silicones, fluorine-modified silicones, and alkyl-modified silicones.

[0112] From the viewpoint of enhancing the continuous repellency effect, the silicone oil is preferably selected from one or more of dimethylpolysiloxane, polydimethylsiloxane alcohol, methylphenylpolysiloxane and modified silicone, more preferably selected from one or more of dimethylpolysiloxane, polydimethylsiloxane alcohol and polyether modified silicone, and even more preferably dimethylpolysiloxane.

[0113] As a dimethylpolysiloxane, one or more can be selected from linear dimethylpolysiloxanes and cyclic dimethylpolysiloxanes. Among these, linear dimethylpolysiloxanes are more preferred from the viewpoint of improving the duration of the repellent effect.

[0114] Commercially available examples of linear dimethyl polysiloxanes include: Shin-Etsu Chemical Co., Ltd.'s KF-96 series, Dow Corning Toray Co., Ltd.'s SH200C series, "2-1184Fluid", Momentive Performance Materials' "Silsoft DML", "Element14 PDMS 5-JC", "Element14 PDMS 10-JC", and "Element14 PDMS 20-JC", etc.

[0115] (b) Ester oil

[0116] From the viewpoint of enhancing the lasting effect of repellency, the preferred ester oils are those represented by any of the following general formulas (1) to (3) and dialkyl carbonate compounds represented by the following general formula (4).

[0117] R 1 -COO-R 2 (1)

[0118] In general formula (1), R 1 R represents a straight-chain or branched alkyl group with 7 to 23 carbon atoms that can be substituted by a hydroxyl group, or an aromatic hydrocarbon group with 6 to 24 carbon atoms. 2 It refers to a straight-chain or branched alkyl or alkenyl group with 1 to 22 carbon atoms.

[0119] In R 1 When the carbon atom is alkyl, from the viewpoint of enhancing the duration of the repellency effect, the number of carbon atoms is preferably 7 or more, more preferably 9 or more, and from the viewpoint of providing a pleasant feel when applied to the skin, the number is preferably 21 or less, more preferably 17 or less. Furthermore, in R... 1 In the case of aromatic hydrocarbon groups, from the viewpoint of enhancing the long-lasting repellency effect, the number of carbon atoms is preferably 8 or more, more preferably 10 or more, and from the viewpoint of providing a good feel when applied to the skin, it is preferably 22 or less, more preferably 20 or less.

[0120] R 2 From the viewpoint of providing a pleasant feel when applied to the skin, straight-chain or branched alkyl or alkenyl groups with 20 or fewer carbon atoms, more preferably 18 or fewer, are preferred. Furthermore, from the viewpoint of providing a pleasant feel when applied to the skin, R is preferred. 1 Or R 2 At least one of them is a branched alkyl group.

[0121] Examples of ester oils represented by general formula (1) include myristyl 2-ethylhexanoate, cetyl 2-ethylhexanoate, stearyl 2-ethylhexanoate, isodecanyl octanoate, isocetyl octanoate, isononyl isononanoate, isotriadecyl isononanoate, cetearyl isononanoate, octyl propyl heptanoate, methyl laurate, isopropyl myristate, octyl dodecyl myristate, isopropyl palmitate, and 2-ethylhexyl palmitate. One or more of the following: isocetyl palmitate, 2-ethylhexyl stearate, isocetyl stearate, isotriadecyl stearate, isopropyl isostearate, octyl isostearate, isocetyl isostearate, isostearyl isostearate, 2-ethylhexyl hydroxystearate, methyl oleate, oleic acid ester, isobutyl oleate, oleic acid ester, alkyl benzoate (alkyl group with 12 to 15 carbon atoms), and diethylhexyl naphthalene.

[0122] (R 3 O)-CH2CH(OR 4 )-CH2(OR 5 (2)

[0123] In general formula (2), R 3 R 4 and R 5 Each is independently a hydrogen atom or a group represented by the general formula (2-1) below, and not all of them are hydrogen atoms.

[0124] -CO-R 6 (2-1)

[0125] (where R is in the formula) 6 This refers to an alkyl or alkenyl group with 7 to 23 carbon atoms, preferably 17 or less, that can be substituted by a hydroxyl group.

[0126] As represented by general formula (2), ester oils may be selected from one or more of tri(2-ethylhexanoic acid) glycerides and tricaprylic acid glycerides. They may also be plant-derived ester oils such as jojoba oil, olive oil, sunflower seed oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grapeseed oil, thistle oil, nightshade oil, macadamia nut oil, corn germ oil, and avocado oil.

[0127] R 7 O-(AO)m-COR8 (3)

[0128] In general formula (3), R 7 R represents an aromatic hydrocarbon group with 6 to 20 carbon atoms. 8 It indicates an alkyl or alkenyl group with 1 to 23 carbon atoms. AO indicates an alkyl group with 2 to 4 carbon atoms, and m indicates the average number of moles of addition with 1 to 50 carbon atoms.

[0129] R 7 From the viewpoint of enhancing the lasting effect of repellency, it is preferable to have 6 or more carbon atoms, and from the viewpoint of providing a good feel when applied to the skin, it is preferable to have 12 or fewer aromatic hydrocarbon groups, more preferably 10 or fewer, and even more preferably benzyl.

[0130] R 8 From the viewpoint of enhancing the lasting effect of repellency, it is preferable to have 7 or more carbon atoms, more preferably 11 or more, and from the viewpoint of providing a good tactile feel when applied to the skin, it is preferable to have 21 or fewer alkyl groups, more preferably 15 or fewer.

[0131] From the viewpoint of enhancing the long-lasting effect of repellency, the AO group is preferably propylene oxide. From the viewpoint of enhancing the long-lasting effect of repellency and providing a good feel when applied to the skin, m is preferably 1 to 10, and more preferably 1 to 5.

[0132] As an ester oil represented by general formula (3), one or more of the following can be listed: an ester of benzyl alcohol in propylene oxide 3-molar adduct and myristic acid (Croda's "Crodamol STS"), and an ester of benzyl alcohol in propylene oxide 3-molar adduct and 2-ethylhexanoic acid (Croda's "Crodamol SFX").

[0133] R 9 -O-(CH2CH2O)v-CO-(OCH2CH2)w-OR 10 (4)

[0134] In general formula (4), R 9 and R 10 Each of the following independently represents an alkyl or alkenyl group with 6 to 22 carbon atoms, and v and w independently represent the average number of addition moles of 0 or 1 to 50.

[0135] R 9 and R 10 From the viewpoint of enhancing the lasting effect of repellency, it is preferable to have 8 or more carbon atoms, and from the viewpoint of providing a good feel when applied to the skin, it is preferable to have 18 or fewer alkyl groups, more preferably 12 or fewer.

[0136] From the viewpoint of providing a pleasant tactile experience when applied to the skin, v and w are preferably numbers of 0 or more than 1 and less than 5, and more preferably 0.

[0137] Examples of dialkyl carbonate compounds represented by general formula (4) include dioctyl carbonate (Cognis' "CETIOL CC").

[0138] Other examples of ester oils besides those mentioned above include: esters of polycarboxylic acids and alcohols, or esters of polyols other than glycerol and fatty acids.

[0139] Specific examples include one or more selected from diisopropyl dimer, diisopropyl adipate, diethoxyethyl succinate, 2-ethylhexyl succinate, propylene glycol didecanoate, neopentyl glycol didecanoate, and neopentyl glycol di(2-ethylhexanoate). Among these, from the viewpoint of enhancing the long-lasting repellent effect, esters of neopentyl glycol and fatty acids are preferred, and more preferably one or more selected from neopentyl glycol didecanoate and neopentyl glycol di(2-ethylhexanoate).

[0140] Of the ester oils mentioned above (b), preferably one or more are selected from the ester oils represented by general formula (1) and esters of neopentyl glycol and fatty acids.

[0141] (c) Ether oil

[0142] From the viewpoint of enhancing the long-lasting repellency effect, dialkyl ether compounds represented by the following general formula (5) or polyoxyalkylene ether compounds represented by the following general formula (6) are preferred as ether oils.

[0143] R 11 -OR 12 (5)

[0144] In general formula (5), R 11 and R 12 Each can be independently represented as a straight-chain or branched alkyl or alkenyl group with 6 to 22 carbon atoms, or an aromatic hydrocarbon group with 6 to 24 carbon atoms.

[0145] R 11 and R 12 From the viewpoint of enhancing the long-lasting effect of repellency, alkyl groups are preferred, and the number of carbon atoms is preferably 8 or more from the viewpoint of enhancing the long-lasting effect of repellency. Furthermore, from the viewpoint of providing a pleasant feel when applied to the skin, the number of carbon atoms is preferably 18 or less, more preferably 16 or less, and even more preferably 12 or less.

[0146] Examples of dialkyl ether compounds represented by general formula (5) include: dihexyl ether, dioctyl ether (Cognis' "CETIOL OE"), dioctyl ether, cetyl-1,3-dimethylbutyl ether (Kao Corporation's "ASE-166K"), etc.

[0147] R 13 -O-(PO)r(EO)sH (6)

[0148] In general formula (6), R 13 The addition of PO and EO indicates alkyl or alkenyl groups with 6 to 22 carbon atoms. PO represents propyleneoxy and EO represents vinyloxy. r represents the average number of moles of addition between 0.1 and 15, and s represents the average number of moles of addition between 0 and 10. When s is not 0, the addition of PO and EO can be random or block.

[0149] R 13 From the viewpoint of enhancing the lasting effect of repellency, the number of carbon atoms is preferably 8 or more, and from the viewpoint of providing a good feel when applied to the skin, it is preferably 20 or less, more preferably 18 or less, and even more preferably 12 or less.

[0150] From the viewpoint of enhancing the duration of the repellency effect, the average added mole number r is preferably 1 or more, more preferably 2 or more, and even more preferably 3 or more. From the viewpoint of providing a pleasant feel when applied to the skin, it is preferably 13 or less, more preferably 10 or less. From the viewpoint of providing a pleasant feel when applied to the skin, the average added mole number s is preferably 5 or less, more preferably 1 or less, and even more preferably 0.

[0151] As the polyoxyalkylene ether compound represented by general formula (6), it is preferably selected from polypropylene glycol, polyoxypropylene octyl ether, polyoxypropylene decyl ether, and polyoxypropylene lauryl ether, where the average addition molar number r of propylene oxy group is 3 or more and less.

[0152] Of the ether oils described above (c), from the viewpoint of enhancing the duration of the repellency effect, the ether oil represented by general formula (5) is preferred.

[0153] (d) Hydrocarbon oil

[0154] Examples of hydrocarbon oils include: liquid paraffin, liquid isoparaffin, squalane, isohexadecane, isoeicosane, hydrogenated polyisobutylene, light liquid isoparaffin, heavy liquid isoparaffin, α-olefin oligomers, and cyclic paraffins.

[0155] Of these, from the viewpoints of enhancing the lasting effect of repellency and providing a pleasant feel when applied to the skin, it is preferable to select one or more of liquid paraffin, liquid isoparaffin, and squalane.

[0156] (e) Aliphatic alcohols

[0157] As an aliphatic alcohol, examples include monocyclic or cyclic aliphatic alcohols, with monocyclic aliphatic alcohols being preferred. From the viewpoint of enhancing the long-lasting repellent effect, the number of carbon atoms in the aliphatic alcohol is preferably 14 or more, more preferably 18 or more, and from the viewpoint of providing a pleasant feel when applied to the skin, the number of carbon atoms is preferably 28 or less, more preferably 24 or less, and even more preferably 22 or less.

[0158] The aforementioned aliphatic alcohols can be any type of straight-chain or branched-chain alcohols, and can be any type of saturated or unsaturated alcohols. From the viewpoint of enhancing the long-lasting effect of repellency and providing a pleasant feel when applied to the skin, branched aliphatic saturated alcohols are preferred.

[0159] Examples of straight-chain aliphatic alcohols include oleyl alcohol, while examples of branched-chain aliphatic saturated alcohols include butyl octanol, butyl decol, hexyl decol, and octyl dodecanol.

[0160] From the perspective of enhancing the lasting effect of repellency and providing a pleasant feel when applied to the skin, branched aliphatic saturated alcohols are preferred, and one or more of acetyldecyl alcohol, hexyldodecyl alcohol, and octyldodecyl alcohol are preferred.

[0161] (f) Polyols

[0162] Examples of polyols include aliphatic alcohols with 2 or more carbon atoms, aromatic alcohols, and sugar alcohols with 4 or more carbon atoms. They can be any type, whether saturated or unsaturated. From the viewpoint of providing a good feel when applied to the skin, it is preferable to select one or more of aliphatic alcohols, aromatic alcohols, and sugar alcohols with 4 or more carbon atoms.

[0163] Examples of aliphatic alcohols with two or more carbon atoms among polyols include: ethylene glycol, propylene glycol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, diethylene glycol, dipropylene glycol, hexanediol, and other diols.

[0164] Furthermore, examples of sugar alcohols mentioned above include: sorbitol, erythritol, pentaerythritol, xylitol, mannitol, etc.

[0165] Of the aforementioned liquid oily components, from the viewpoint of enhancing the long-lasting repellent effect, it is preferably selected from one or more of (a) silicone oil, (b) ester oil, (c) ether oil, and (d) hydrocarbon oil; more preferably, it is selected from one or more of (a) silicone oil, (b) ester oil, and (d) hydrocarbon oil; further preferably, it is selected from one or more of (a) silicone oil and (b) ester oil; and even more preferably, it is (a) silicone oil. Of the (a) silicone oil, it is preferably selected from one or more of dimethyl polysiloxane, polydimethylsiloxane alcohol, methylphenyl polysiloxane, and modified silicone; more preferably, it is selected from one or more of dimethyl polysiloxane, polydimethylsiloxane alcohol, and polyether-modified silicone; more preferably, it is dimethyl polysiloxane; and even more preferably, it is linear dimethyl polysiloxane.

[0166] (Content of component (A))

[0167] Regarding the content of component (A) in the composition of the present invention, from the viewpoint of enhancing the long-lasting repellency effect, it is 13% by mass or more, preferably 20% by mass or more, more preferably 25% by mass or more; from the viewpoint of enhancing the long-lasting repellency effect, ensuring the long-term storage stability of the composition, suppressing odors originating from component (A), and improving the user experience of the composition, it is 99.95% by mass or less, preferably 80% by mass or less, more preferably 50% by mass or less, further preferably 40% by mass or less, and further more preferably 35% by mass or less. Therefore, the content of component (A) in the composition of the present invention is 13 to 99.95% by mass, preferably 13 to 80% by mass, more preferably 13 to 50% by mass, further preferably 20 to 40% by mass, and further more preferably 25 to 35% by mass.

[0168] <Ingredient (B): Fragrance>

[0169] The composition of the present invention contains one or more fragrances selected from (B1) to (B9) below as component (B).

[0170] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolactone

[0171] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0172] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctanal and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0173] (B4) One or more aromatic alcohols selected from phenethylmethyl ethyl methanol, cinnamyl alcohol and eugenol

[0174] (B5)2-(4-methyl-2-thiazolyl)ethanol

[0175] (B6)2-Ethyl phenylacetate

[0176] (B7) Acetate (3-pentyloxetane-4-yl) ester

[0177] (B8) Dimethylphenethyl methanol acetate

[0178] (B9) Methyl anthranilate

[0179] The fragrance in component (B) is believed to act on the chemosensory system of flying pests such as mosquitoes, thus also having a repellent effect. Compared with using component (A) or component (B) alone, the combined use of component (A) and component (B) synergistically enhances the sustained pest repellency effect.

[0180] Octahydro-2H-1-benzopyran-2-one is also known as "octahydrocoumarin". 7-hydroxy-3,7-dimethyloctanal is also known as "hydroxycitronellol", octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde is also known as "scentenal", 2-(4-methyl-2-thiazolyl)ethanol is also known as "sulfurol", and (3-pentyloxacyclohexane-4-yl) acetate is also known as "jasmonyl".

[0181] Component (B) may be used alone or in combination of two or more. From the viewpoint of suppressing strong odors and enhancing the long-lasting repellent effect, component (B) is preferably selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, γ-undecanolide, 9-ethylidene-3-oxatricyclo[6.2.1.0]. 2,7 Undecane-4-one, octahydro-7-methyl-1,4-methylbridged naphthyl-6(2H)-one, 7-hydroxy-3,7-dimethyloctanal, octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde, phenethylmethylethyl methanol, eugenol, 2-(4-methyl-2-thiazolyl)ethanol, (3-pentyloxacyclohexane-4-yl) acetate, and methyl anthranilate, more preferably selected from octahydro-2H-1-benzopyran-2-one, γ-undecyl lactone, 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7The undecane-4-one and (3-pentyloxacyclohexane-4-yl) ester are selected from one or more, and more preferably from one or more of octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctanal, and more preferably from octahydro-2H-1-benzopyran-2-one.

[0182] (Content of component (B))

[0183] Furthermore, the content of component (B) in the composition of the present invention, from the viewpoint of suppressing odors originating from component (A) and enhancing the repellency effect, is 0.05% by mass or more, preferably 0.1% by mass or more, more preferably 0.2% by mass or more, and even more preferably 0.3% by mass or more. Also, the content of component (B) in the composition of the present invention, from the viewpoint of suppressing strong odors originating from component (B), is 3.5% by mass or less, preferably 2.5% by mass or less, more preferably 2.0% by mass or less, even more preferably 1.0% by mass or less, and even more preferably 0.7% by mass or less. Therefore, the content of component (B) in the composition of the present invention is 0.05 to 3.5% by mass, preferably 0.1 to 2.5% by mass, more preferably 0.2 to 2.0% by mass, even more preferably 0.2 to 1.0% by mass, and even more preferably 0.3 to 0.7% by mass.

[0184] In the composition of the present invention, the mass ratio of component (A) to component (B) [(A) / (B)] is preferably 10 or more, more preferably 15 or more, more preferably 30 or more, and more preferably 40 or more, from the viewpoint of suppressing odor and ensuring the long-term storage stability of the composition. From the viewpoint of enhancing the sustained effect of pest repellency, it is preferably 400 or less, more preferably 300 or less, more preferably 150 or less, more preferably 120 or less, more preferably 100 or less, and more preferably 70 or less. Therefore, the mass ratio of component (A) to component (B) [(A) / (B)] is preferably 10 to 400, more preferably 15 to 300, more preferably 15 to 150, more preferably 15 to 150, more preferably 15 to 120, more preferably 15 to 100, more preferably 30 to 100, and more preferably 40 to 70.

[0185] <Ingredient (C): Water>

[0186] From the viewpoint of enhancing the lasting effect of repellency and producing a composition with a pleasant user experience, the composition of the present invention preferably contains water as component (C). Regarding the content of component (C) in the composition of the present invention, from the viewpoint of enhancing the lasting effect of repellency and producing a composition with a pleasant user experience, it is preferably 5% by mass or more, more preferably 10% by mass or more, and even more preferably 35% by mass or more, and even more preferably 50% by mass or more. Furthermore, from the viewpoint of enhancing the lasting effect of repellency, it is preferably 86.95% by mass or less, more preferably 85% by mass or less, even more preferably 80% by mass or less, and even more preferably 75% by mass or less. Therefore, the content of component (C) in the composition of the present invention is preferably 5 to 86.95% by mass or less, more preferably 5 to 85% by mass, even more preferably 10 to 80% by mass, even more preferably 35 to 75% by mass, and even more preferably 50 to 75% by mass.

[0187] This invention can be applied to various compositional forms, such as non-aqueous compositions, water-in-oil compositions, and oil-in-water compositions. From the viewpoint of suppressing odors originating from component (A), it is preferable to produce an oil-in-water composition. Furthermore, when producing an oil-in-water composition, the content of component (C) in the composition is preferably 35% by mass or more, more preferably 40% by mass or more, and even more preferably 50% by mass or more, from the viewpoint of suppressing odors originating from component (A) and ensuring the long-term storage stability of the composition. Also, from the viewpoint of improving the long-lasting repellency effect, it is preferably 86.95% by mass or less, more preferably 80% by mass or less, and even more preferably 75% by mass or less.

[0188] Furthermore, from the viewpoint of enhancing the long-lasting effect of repellency, it is preferable to formulate a water-in-oil composition. Moreover, when formulating a water-in-oil composition, the content of component (C) in the composition is preferably 5% by mass or more, more preferably 10% by mass or more, and even more preferably 15% by mass or more, from the viewpoint of providing a pleasant feel when applied to the skin. Also, from the viewpoint of enhancing the long-lasting effect of repellency, it is preferably 40% by mass or less, more preferably 30% by mass or less, and even more preferably 25% by mass or less.

[0189] When the composition of the present invention contains component (C), the mass ratio of component (A) to water [(A) / (C)] is preferably 0.05 or more, more preferably 0.1 or more, more preferably 0.15 or more, and more preferably 0.3 or more, from the viewpoint of ensuring the long-term storage stability of the composition and producing a composition with a good user experience. It is preferably 10 or less, more preferably 3 or less, more preferably 1 or less, and more preferably 0.7 or less.

[0190] <Ingredient (D): Tackifier>

[0191] The compositions of the present invention may further contain a thickener as component (D). From the viewpoints of enhancing the lasting effect of repellency by adjusting the fluidity after application to the skin, ensuring excellent spreadability on the skin by ensuring good dispersion or dissolution of each component, and ensuring the long-term storage stability of the composition, the thickener is preferably a thickener having moderate emulsifying energy (i.e., surface activity). In the present invention, a formulation having both emulsifying energy and thickening effect is designated as a thickener.

[0192] As a component (D), examples include: water-soluble cationic polymers, anionic polymers, nonionic polymers, and amphoteric or bipolar polymers.

[0193] As cationic polymers, examples include: hydroxyethyl cellulose (polyquaternium-10) containing chlorinated O-[2-hydroxy-3-(trimethylammonium)propyl] groups, diethyl sulfate of vinylpyrrolidone-dimethylaminomethyl ethyl methacrylate copolymer (polyquaternium-11), and chlorinated methylvinylimidazolium-vinylpyrrolidone copolymer, etc.

[0194] As anionic polymers, specifically, the following can be listed: carboxyvinyl polymers, carboxymethyl cellulose, carrageenan, xanthan gum, polystyrene sulfonate, agar, solanum, guizitan gum, pectin, alginate, acrylate-alkyl methacrylate copolymer, (sodium acrylate / sodium acryloyl dimethyl taurate) copolymer, polyacrylamide, (ammonium acryloyl dimethyl taurate / vinylpyrrolidone) copolymer, (acrylate / alkyl (C10-C30) acrylate) crosspolymer, (ammonium acryloyl dimethyl taurate / behenol polyether-25 methacrylate) crosspolymer, (hydroxyethyl acrylate / sodium acryloyl dimethyl taurate) copolymer, (acrylamide / ammonium acrylate) copolymer, (sodium acrylate / acryloyl dimethyl taurate / dimethylacrylamide) crosspolymer, polyacrylate-13, polyacrylate crosspolymer-6, alkali metal salts of poly(acrylic acid), hyaluronic acid or alkali metal salts thereof.

[0195] As nonionic polymers, examples include: cellulose ethers (hydroxybutyl methyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, ethyl hydroxyethyl cellulose, hydroxyethyl cellulose, etc.), propylene glycol alginate, poly(ethylene oxide), polyvinyl alcohol, polyvinylpyrrolidone, hydroxypropyl guar gum, locust bean gum, amyl starch, hydroxyethyl amyl starch, starch and starch derivatives, and mixtures thereof.

[0196] As amphoteric or bipolar polymer, examples include: octylacrylamide / acrylate / butylaminoethyl methacrylate copolymer, polyquaternium-47, polyquaternium-43, etc.

[0197] Ingredient (D) may be used in one or in combination of two or more. From the perspectives of enhancing the duration of pest repellency by adjusting the fluidity after application to the skin, ensuring excellent spreadability on the skin by ensuring good dispersion or dissolution of each component, and ensuring long-term preservation stability of the composition, component (D) is preferably selected from one or more of anionic and nonionic polymers, preferably from one or more of carboxyvinyl polymers, alkyl acrylate copolymers, (sodium acrylate / sodium acryloyl dimethyl taurate) copolymers, (acrylate / alkyl (C10-C30) acrylate) crosslinking polymers, (ammonium acryloyl dimethyl taurate / behenol polyether-25 methacrylate) crosslinking polymers, and cellulose ethers, more preferably from one or more of (sodium acrylate / sodium acryloyl dimethyl taurate) copolymers, (acrylate / alkyl (C10-C30) acrylate) crosslinking polymers, and (ammonium acryloyl dimethyl taurate / behenol polyether-25 methacrylate) crosslinking polymers.

[0198] Commercially available formulations as component (D) include, for example, Lubrizol Advanced Materials' "CARBOPOL 980", "CARBOPOL 981", "CARBOPOL 1342", "CARBOPOL ETD2020", "PEMULEN TR-1", and "PEMULEN TR-2", Dow Chemical's "Aculyn 22", and Clariant Iberica Production S.A.'s "Aristoflex AVC" and "Aristoflex HMB". Furthermore, thickeners can also be formulated as dispersions in a dispersion medium.

[0199] Regarding the content of component (D) in the composition of the present invention, from the viewpoints of enhancing the lasting repellency effect, ensuring good dispersion or dissolution of each component to guarantee excellent spreadability on the skin, and ensuring the long-term storage stability of the composition, it is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and even more preferably 0.1% by mass or more. From the same viewpoints, it is preferably 5% by mass or less, more preferably 3% by mass or less, and even more preferably 1% by mass or less. Furthermore, when the composition of the present invention contains a tackifier with surface-active properties, the content of other surfactants in the composition is preferably 1.5% by mass or less, more preferably 1% by mass or less.

[0200] <Other Ingredients>

[0201] The compositions of the present invention may appropriately contain ingredients other than those described above, within a range that does not impair the effects of the present invention, such as surfactants, preservatives, colorants, humectants, fragrances other than ingredient (B), pH adjusters, etc. Furthermore, they may also contain pharmaceutically active or physiologically active ingredients such as vitamins, blood circulation promoters, reactive oxygen species scavengers, anti-inflammatory agents, whitening agents, and bactericides. Moreover, fragrances may be used for other purposes, such as as bactericides.

[0202] The composition of the present invention contains ingredients (A) and (B) as repellent ingredients to repel pests, and does not contain any other pest repellents in an effective amount, which is preferable from the viewpoint of preventing allergies or rough skin in users.

[0203] The composition of the present invention exhibits a sustained repellent effect even when it does not contain an effective amount of insect repellent other than components (A) and (B). In other words, if the composition of the present invention contains an existing insect repellent other than components (A) and (B) in an amount less than the lower limit of the effective amount, it will prevent insects from landing and remaining on the spot, thus demonstrating the dwell-inhibiting effect of the present invention. That is, the composition of the present invention may substantially not contain any existing insect repellent other than components (A) and (B).

[0204] Here, the term "not containing in an effective amount" of insect repellent other than component (A) and component (B) generally refers to the content of insect repellent other than component (A) and component (B) in the composition of the present invention, preferably 15% by mass or less, more preferably 10% by mass or less, even more preferably 5% by mass or less, even more preferably 4% by mass or less, even more preferably 3% by mass or less, even more preferably 1% by mass or less.

[0205] For example, the effective amount of existing insect repellents can be referenced from the minimum effective amount disclosed by the manufacturers of the various repellent products. More specifically, the following are existing insect repellents: DEET: N,N-diethyltoluamide has an effective amount of 4% by mass or more, preferably 10% by mass or more; Icaridin: 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester has an effective amount of 4% by mass or more; IR3535: 3-(acetylbutyl)aminopropionate ethyl ester has an effective amount of 4% by mass or more; and citronella oil has an effective amount of 10% by mass or more.

[0206] Furthermore, the effective amount of existing pest repellents can also be determined through the repellency evaluation tests described below.

[0207] (Avoidance Evaluation Test)

[0208] Place 100 mated female mosquitoes (Aedes albopictus) in a mesh-enclosed plastic cage (30×30×30cm: BugDorm-1 cage). Insert your forearm into a KUALATEC Super Long Glove (50cm) (ASONE Co., Ltd., Catalog number: 3-6432-02), with a 5cm x 4cm rectangular cut on the elbow side approximately 15cm from the wrist. Without applying any ointment to the exposed area, insert your arm into the cage and confirm that mosquitoes land on at least two points on exposed skin within 2 minutes, remaining there for at least 1 second. If the mosquitoes do not remain for at least 1 second, prepare more mosquitoes. Hereinafter, a stay of at least 1 second will be abbreviated as "stay".

[0209] The test for evaluating the solution as an insect repellent involves using ethanol to apply the sample at a concentration of 2 mg / cm³. 2 Apply the mixture to exposed skin areas (5cm x 4cm) after adjusting the concentration.

[0210] Using an automated pipette (PIPETMAN), apply the concentrated solution to the exposed area and spread it evenly over the entire exposed skin (required solution volume: 40–50 μl). Let it stand for 3 minutes before starting the test.

[0211] The test was conducted by inserting an arm coated with the evaluation sample into a cage for 2 minutes and counting the number of pauses. The test ended when there were two pauses in total. Before the end of the test, the arm was inserted for 2 minutes every 30 minutes. If a second pause occurred at the 30-minute mark, the duration of the avoidance effect was determined to be 0 minutes; if a second pause occurred at the 60-minute mark, the duration of the avoidance effect was determined to be 30 minutes. The test was conducted by three subjects, and the average duration of the avoidance effect was calculated.

[0212] In this experiment, the concentration of the pest repellent that shows an average repellency duration of more than 2 hours can be defined as the effective concentration (effective amount) of the pest repellent.

[0213] The compositions of the present invention have a sustained repellent effect even if they do not contain an effective amount of insect repellent other than components (A) and (B). Therefore, it is preferable that they do not contain substantially any insect repellent other than components (A) and (B). In the compositions of the present invention, the content of insect repellent other than components (A) and (B) is preferably 0.5% by mass or less, more preferably 0.1% by mass or less, more preferably 0.01% by mass or less, and more preferably substantially 0% by mass.

[0214] Existing insect repellents other than components (A) and (B) include: DEET, icariin, dimethyl phthalate, 2-ethyl-1,3-hexanediol, p-menthane-3,8-diol, caretane-3,4-diol, di-n-butyl succinate, anisole, rotenone, ethyl 3-(acetylbutyl)aminopropionate, citronellol, eucalyptol, α-pinene, geraniol, citronellol, camphor, linalool, 2-undecone, and other well-known insect repellent compounds, as well as repellent essential oils such as citronella oil and lemongrass oil. "Repellent essential oils" refer to substances in essential oils obtained through extraction, distillation, or pressing of plant components that have insect-repelling effects.

[0215] The compositions of the present invention can be manufactured by conventional methods. For example, they can be manufactured by mixing components (A), (B), and other components as needed, using a known apparatus.

[0216] There are no particular limitations on the pests that can be repelled by the compositions of the present invention, and they are more effective against flying pests.

[0217] The term "flying pests" refers to pests that approach humans or other animals while flying and suck their blood from their skin, or pests that spread pathogens and bacteria while flying even if they do not suck blood, or pests whose flight behavior itself brings discomfort to humans.

[0218] Specific examples of flying pests include: Culex pipiens pallens, Culex tritaeniorhynchus, Culex pipiens molestus, Culex quinquefasciatus, and other Culex mosquitoes; Aedes aegypti, Aedes albopictus, Anopheles sinensis, Aedes togoi, Anopheles gambiae, Anopheles stephensi, and other mosquitoes; Chironomus yoshimatsui, Propsilocerus akamusi, and other midges; Twinnia japonensis, Prosimulium yezoense, Odagmia aokii, and other black flies; and houseflies (Musca). Domestic flies, stable flies (Muscina stabulans), summer toilet flies (Fannia canicularis), blowflies (Calliphoridae), flesh flies (Sarcophagidae), gray ground flies (Delia platura), onion flies (Delia antiqua), fruit flies (fruitflies), fruit vinegar flies (fruit vinegar flies), moth flies, tsetse flies, stable stinging flies (Stomoxys calcitrans), etc.; horseflies, blind horseflies, and tussock flies, etc.; Japanese midges (Leptoconopsnipponensis), Sumatran midges (Culicoides sumatrae), Arakawa midges (Culicoides arakawae), etc.; Japanese wasps (Vespa simillima xanthoptera), dark yellow long-legged wasps (Polistes jokahamae), honeybees, etc.

[0219] The compositions of the present invention exhibit particularly excellent and sustained repellent effects against mosquitoes of these species. Among the aforementioned mosquitoes, the repellent effects against Culex pipiens pallens, Culex tritaeniorhynchus, Culex suberectus, Culex quinquefasciatus, Aedes aegypti, and Aedes albopictus are particularly effective.

[0220] Methods for repelling and inhibiting pests' stay

[0221] The pest repellency method of the present invention is carried out by applying the pest repellency composition of the present invention to the surface of human skin.

[0222] Furthermore, the pest retention inhibition method of the present invention prevents pests from remaining on human skin by attaching the pest retention inhibition composition of the present invention to the limbs of pests, especially flying pests. Hereinafter, these methods will also be collectively referred to as "the methods of the present invention".

[0223] Here, "applying to the skin surface" refers not only to applying the composition directly to the skin surface with hands or other means, but also to applying the composition to the skin surface through spraying or other means.

[0224] From the perspective that the amount of the composition applied to the skin surface enhances the lasting effect of the repellent, each 1cm 2 Preferably, the dosage is 0.1 mg or more, more preferably 0.2 mg or more, and even more preferably 0.25 mg or more. Furthermore, from the viewpoint of suppressing stickiness and economic efficiency, the upper limit of the application amount is [amount] per 1 cm [unit of area]. 2 Preferably, it is 10 mg or less, more preferably 8 mg or less, and even more preferably 5 mg or less.

[0225] From the viewpoint of providing a repellent composition that offers excellent sustained mosquito repellency, safety, and superior user experience by suppressing the strong odor originating from the repellent ingredient, the composition of the present invention is preferably an oil-in-water mosquito repellent composition or a mosquito dwell-inhibiting composition containing the following components (A) to (C), wherein the content of the insect repellent other than component (A) and component (B) is 15% by mass or less.

[0226] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0227] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0228] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0229] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0230] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0231] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0232] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0233] (B6)2-ethyl phenylacetate

[0234] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0235] (B8) Dimethylphenethyl methanol acetate,

[0236] (B9) Methyl anthranilate;

[0237] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0238] From the viewpoint of providing a repellent composition that offers excellent sustained mosquito repellency, safety, and superior user experience by suppressing the strong odor originating from the repellent ingredient, the composition of the present invention is preferably a water-in-oil type mosquito repellent composition or mosquito dwell-inhibiting composition containing the following components (A) to (C), wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400 or less, and the content of the pest repellent other than component (A) and component (B) is 15% by mass or less.

[0239] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0240] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0241] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0242] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0243] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0244] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0245] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0246] (B6)2-ethyl phenylacetate

[0247] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0248] (B8) Dimethylphenethyl methanol acetate,

[0249] (B9) Methyl anthranilate;

[0250] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0251] From the viewpoint of providing a repellent composition that offers excellent sustained mosquito repellency, safety, and suppresses strong odors originating from the repellent ingredient, resulting in a superior user experience, the composition of the present invention is preferably a water-in-oil type mosquito repellent composition or mosquito retention inhibition composition containing the following components (A) to (C), wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400 or less, and the content of the pest repellent other than component (A) and component (B) is 15% by mass or less.

[0252] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0253] (B) One or more fragrances selected from octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctaldehyde: 0.05% by mass to 3.5% by mass;

[0254] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0255] From the viewpoint of providing a repellent composition that offers excellent sustained mosquito repellency, safety, and suppresses strong odors originating from the repellent ingredient, resulting in a superior user experience, the composition of the present invention is preferably a water-in-oil type mosquito repellent composition or mosquito dwell-inhibiting composition containing the following components (A) to (D), wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400 or less, and the content of the insect repellent other than component (A) and component (B) is 15% by mass or less.

[0256] (A) One or more non-volatile liquid oily components selected from silicone oil, ester oil and hydrocarbon oil, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% to 50% by mass.

[0257] (B) One or more fragrances selected from octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctaldehyde: 0.05% by mass to 3.5% by mass;

[0258] (C) Water: ≥35% by mass and ≤86.95% by mass;

[0259] (D) Tackifier: 0.05% by mass or more, 3% by mass or less.

[0260] The pest repellency method of the present invention repels pests by preventing them from settling on objects coated or covered with the composition of the present invention, even if mosquitoes or other pests land on them. Specifically, it has the following retention inhibition effect: after mosquitoes or other pests land on the skin of humans or animals, they are prevented from remaining on the animal's skin surface for a period sufficient for a piercing needle to penetrate, for example, more than one second. This effect is based on a previously undeveloped pest repellency principle and is relatively safe, without side effects such as rough skin.

[0261] Regarding the above-described embodiments, the present invention further discloses the following embodiments.

[0262] <1>

[0263] An insect repellent composition or insect retention inhibitory composition, comprising components (A) and (B) thereof, wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400.

[0264] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass or more and 99.95% by mass.

[0265] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0266] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0267] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0268] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0269] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0270] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0271] (B6)2-ethyl phenylacetate

[0272] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0273] (B8) Dimethylphenethyl methanol acetate,

[0274] (B9) Methyl anthranilate.

[0275] <2>

[0276] In the composition described in <1>, the mass ratio of component (A) to component (B) [(A) / (B)] is preferably 15 or more, more preferably 30 or more, more preferably 40 or more, and preferably 300 or less, more preferably 150 or less, more preferably 120 or less, more preferably 100 or less, and more preferably 70 or less.

[0277] <3>

[0278] The composition described in <1> or <2> contains an insect repellent other than component (A) and component (B) at a content of 15% by mass or less, preferably 10% by mass or less, more preferably 5% by mass or less, even more preferably 4% by mass or less, even more preferably 3% by mass or less, even more preferably 1% by mass or less.

[0279] <4>

[0280] The composition described in <3>, wherein the pest repellent other than component (A) and component (B) is selected from one or more of DEET, icosardine, dimethyl phthalate, 2-ethyl-1,3-hexanediol, p-menthane-3,8-diol, caretane-3,4-diol, di-n-butyl succinate, hydroxyanisole, rotenone, ethyl 3-(acetylbutyl)aminopropionate, citronellol, eucalyptol, α-pinene, geraniol, citronellol, camphor, linalool, 2-undecone, citronellol oil and lemongrass oil.

[0281] <5>

[0282] The composition described in any one of <1> to <4>, wherein the surface tension of component (A) at 25°C is 15 mN / m or more, preferably 17 mN / m or more, and 30 mN / m or less, preferably 28 mN / m or less, more preferably 25 mN / m or less, and even more preferably 23 mN / m or less, and even more preferably 21 mN / m or less.

[0283] <6>

[0284] The composition described in any one of <1> to <5>, wherein the viscosity of component (A) at 23°C, as measured by a type B rotational viscometer, is 1 mPa·s or more and 300 mPa·s or less, preferably 210 mPa·s or less, more preferably 100 mPa·s or less, further preferably 60 mPa·s or less, further more preferably 40 mPa·s or less, and further more preferably 30 mPa·s or less.

[0285] <7>

[0286] The composition described in any one of <1> to <6>, wherein component (A) is selected from one or more of silicone oil, ester oil, ether oil and hydrocarbon oil, preferably selected from one or more of silicone oil, ester oil and hydrocarbon oil, more preferably selected from one or more of silicone oil and ester oil, and even more preferably silicone oil.

[0287] <8>

[0288] The composition described in any one of <1> to <7>, wherein the content of component (A) is preferably 20% by mass or more, more preferably 25% by mass or more, and preferably 80% by mass or less, more preferably 50% by mass or less, and even more preferably 40% by mass or less, and even more preferably 35% by mass or less.

[0289] <9>

[0290] The composition described in any one of <1> to <8>, wherein component (B) is preferably selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, γ-undecanolide, 9-ethylidene-3-oxatricyclo[6.2.1.0]2,7 The undecane-4-one, octahydro-7-methyl-1,4-methylbridged naphthol-6(2H)-one, 7-hydroxy-3,7-dimethyloctanal, octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxal, phenethylmethylethyl methanol, eugenol, 2-(4-methyl-2-thiazolyl)ethanol, (3-pentyloxacyclohexane-4-yl) acetate and methyl anthranilate, more preferably selected from octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctanal, and even more preferably octahydro-2H-1-benzopyran-2-one.

[0291] <10>

[0292] The composition described in any one of <1> to <9>, wherein the content of component (B) in the composition is preferably 0.1% by mass or more, more preferably 0.2% by mass or more, more preferably 0.3% by mass or more, and preferably 2.5% by mass or less, more preferably 2.0% by mass or less, more preferably 1.0% by mass or less, and more preferably 0.7% by mass or less.

[0293] <11>

[0294] The composition described in any one of <1> to <10> contains water as a component (C).

[0295] <12>

[0296] The composition described in <11> contains component (C) in a quantity of 5% by mass or more, preferably 10% by mass or more, more preferably 35% by mass or more, and even more preferably 50% by mass or more, and is 86.95% by mass or less, preferably 85% by mass or less, more preferably 80% by mass or less, and even more preferably 75% by mass or less.

[0297] <13>

[0298] The composition described in <11> or <12> is an oil-in-water type composition, wherein the content of component (C) in the composition is preferably 35% by mass or more, more preferably 40% by mass or more, more preferably 50% by mass or more, and preferably 86.95% by mass or less, more preferably 80% by mass or less, and more preferably 75% by mass or less.

[0299] <14>

[0300] The composition described in <11> or <12> is a water-in-oil type composition, wherein the content of component (C) in the composition is preferably 5% by mass or more, more preferably 10% by mass or more, and even more preferably 15% by mass or more, and is 40% by mass or less, preferably 30% by mass or less, and more preferably 25% by mass or less.

[0301] <15>

[0302] The composition described in any one of <11> to <14>, wherein the mass ratio of component (A) to component (C) [(A) / (C)] is preferably 0.05 or more, more preferably 0.1 or more, more preferably 0.15 or more, more preferably 0.3 or more, and preferably 10 or less, more preferably 3 or less, more preferably 1 or less, and more preferably 0.7 or less.

[0303] <16>

[0304] The composition described in any one of <1> to <15> further contains, as component (D), a tackifier preferably at 0.01% by mass or more, more preferably at 0.05% by mass or more, more preferably at 0.1% by mass or more, and preferably at 5% by mass or less, more preferably at 3% by mass or less, and more preferably at 1% by mass or less.

[0305] <17>

[0306] A water-in-oil type mosquito repellent composition or mosquito retention inhibitory composition, wherein the composition contains the following components (A) to (C), wherein the content of the insect repellent other than component (A) and component (B) is 15% by mass or less.

[0307] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0308] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0309] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0310] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0311] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0312] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0313] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0314] (B6)2-ethyl phenylacetate

[0315] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0316] (B8) Dimethylphenethyl methanol acetate,

[0317] (B9) Methyl anthranilate;

[0318] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0319] <18>

[0320] A water-in-oil type mosquito repellent composition or mosquito retention inhibitory composition, comprising the following components (A) to (C), wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400, and the content of the insect repellent other than component (A) and component (B) is 15% by mass or less.

[0321] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0322] (B) One or more flavorings selected from (B1) to (B9) below: 0.05% by mass to 3.5% by mass.

[0323] (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide

[0324] (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one

[0325] (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde.

[0326] (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol.

[0327] (B5)2-(4-methyl-2-thiazolyl)ethanol,

[0328] (B6)2-ethyl phenylacetate

[0329] (B7) Acetate (3-pentyloxetane-4-yl) ester,

[0330] (B8) Dimethylphenethyl methanol acetate,

[0331] (B9) Methyl anthranilate;

[0332] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0333] <19>

[0334] A water-in-oil type mosquito repellent composition or mosquito retention inhibitory composition, comprising the following components (A) to (C), wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400, and the content of the insect repellent other than component (A) and component (B) is 15% by mass or less.

[0335] (A) A non-volatile liquid oily component selected from silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol and polyol with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% by mass to 50% by mass.

[0336] (B) One or more fragrances selected from octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctaldehyde: 0.05% by mass to 3.5% by mass;

[0337] (C) Water: 35% by mass or more, 86.95% by mass or less.

[0338] <20>

[0339] A water-in-oil type mosquito repellent composition or mosquito retention inhibitory composition, comprising the following components (A) to (D), wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 10 to 400, and the content of the insect repellent other than component (A) and component (B) is 15% by mass or less.

[0340] (A) One or more non-volatile liquid oily components selected from silicone oil, ester oil and hydrocarbon oil, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 400 mPa·s at 23°C as measured by a B-type rotational viscometer: 13% to 50% by mass.

[0341] (B) One or more fragrances selected from octahydro-2H-1-benzopyran-2-one and 7-hydroxy-3,7-dimethyloctaldehyde: 0.05% by mass to 3.5% by mass;

[0342] (C) Water: ≥35% by mass and ≤86.95% by mass;

[0343] (D) Tackifier: 0.05% by mass or more, 3% by mass or less.

[0344] <21>

[0345] The composition described in any one of <17> to <20>, wherein the pest repellent other than component (A) and component (B) is selected from one or more of DEET, icosardine, dimethyl phthalate, 2-ethyl-1,3-hexanediol, p-menthane-3,8-diol, caretane-3,4-diol, di-n-butyl succinate, hydroxyanisole, rotenone, ethyl 3-(acetylbutyl)aminopropionate, citronellol, eucalyptol, α-pinene, geraniol, citronellol, camphor, linalool, 2-undecone, citronellol oil and lemongrass oil.

[0346] <22>

[0347] A method for repelling pests, wherein a composition described in any one of <1> to <21> is applied to the surface of human skin.

[0348] <23>

[0349] A method for inhibiting the dwelling of pests, wherein the pest is prevented from dwelling on human skin by attaching a composition as described in any one of <1> to <21> to the limbs of the pest.

[0350] [Example]

[0351] The present invention will now be described through examples, but the invention is not limited to the scope of these examples. Furthermore, in these examples, various measurements and evaluations are performed using the following methods.

[0352] (Surface tension of liquid oily components)

[0353] The surface tension of the liquid oily component was measured using an automatic surface tension meter, "Tensiometer K100" (KRUSS), using the Wilhelmy method with platinum plates at 25°C.

[0354] (Viscosity of liquid oil components)

[0355] As a Type B rotational viscometer conforming to JIS K7117-1:1999, the "Viscometer TVB-10" from Toki Sangyo Co., Ltd. was used. Because the viscosity values ​​of each sample varied considerably, it was difficult to accurately measure all components under a single measurement condition. Therefore, two rotors were used for the measurement. First, the viscosity was measured using rotor M2 at 23°C and a rotation speed of 12 rpm. Then, for components with a viscosity of 2500 mPa·s or higher, the viscosity was measured again at a rotation speed of 6 rpm to obtain the viscosity value.

[0356] On the other hand, for components with a viscosity of less than 20 mPa·s, the viscosity value was obtained again by using an L-connector (Adapter) as a low-viscosity rotor at 23°C and setting the rotation speed to 30 rpm.

[0357] (Evaluation of the sustained effectiveness of pest repellency)

[0358] (I) Preparation of Aedes albopictus

[0359] Aedes albopictus is a mosquito that grows into an adult by being raised in cages using Aedes albopictus eggs provided by Sumitomo Technoservice Co., Ltd. at 27°C and 60% relative humidity (RH).

[0360] Fill a transparent plastic dish with about 1 cm of water and place filter paper containing purchased eggs inside to allow the eggs to hatch into pupae. After hatching, feed the pupae daily with tropical fish food (Tetramine) intended for larval feeding. After one week, collect the pupae using a dropper, transfer them to a 20 mL plastic cup, and then place them in a netted cage. For the pupae, feed them 10% by weight sucrose (used as adult food) in a 25 mL plastic tube. After emergence, rearrange male and female mosquitoes in the same cage for 5 days to allow mating. After 5 days, collect the adults using a siphon, anesthetize them on ice for 5 minutes, and then visually distinguish between male and female mosquitoes. Only collect the females for evaluation.

[0361] (II) Determination of repellency duration (repellency rate 3 hours after application of the composition)

[0362] Two hundred female Aedes albopictus mosquitoes were placed in a net cage (30×30×30cm) and the experiment was conducted at 27°C and 60% RH. In the repellency test, a biomimetic skin plate (BEAULAX, 4.5cm×4.5cm) that replicated the surface of a human skin was used, heated to 40°C by a heater. The net cage had a 4.5cm×4.5cm opening, allowing mosquitoes to land directly on the biomimetic skin.

[0363] The mosquito repellency rate is calculated as follows.

[0364] (1) Measurement of the number of landings

[0365] The heated bionic skin (without the composition applied) was attached to a net cage containing mosquitoes. After blowing air on the mosquitoes for 5 seconds to revive them, the number of mosquitoes that landed on the bionic skin was counted every 10 seconds for 2 minutes. The average number of mosquitoes that landed was set as 1.

[0366] (2) Calculation of repellency rate 3 hours after application of the composition

[0367] Secondly, apply 2mg / cm to the bionic skin. 2 The test subject composition was applied to the net cage after 3 hours. After blowing air on it for 5 seconds to revive the mosquitoes, the number of mosquitoes that landed on the bionic skin was measured every 10 seconds within 2 minutes, and the average number was set as the landing number 2.

[0368] The repellency rate of the application composition 3 hours later in each case was calculated using the values ​​of the above-mentioned landing number 1 and 2, according to the formula "repellency rate" = (landing number 1 - landing number 2) / (landing number 1) × 100 (%).

[0369] (Evaluation of odor intensity)

[0370] The compositions in each example were prepared at 2 mg / cm². 2 The odor was applied to a 4.5 x 4.5 cm area on the inner forearm and left to stand for 3 hours. Afterward, three evaluators conducted a sensory evaluation to determine the odor intensity. Odor intensity was evaluated across six stages (5: strong odor, 4: strong odor, 3: easily perceptible odor, 2: weak odor with some odor, 1: barely perceptible odor, 0: no odor). The average of the three evaluators' assessments was taken as the odor intensity. Odor intensities suitable for skin application were classified as follows. Furthermore, lower values ​​indicate less odor and are considered superior compositions.

[0371] A: Below 2.5

[0372] B: More than 2.5 and less than 3.5

[0373] C: Over 3.5

[0374] (Evaluation of long-term storage stability)

[0375] Each example composition was placed into a 100mL glass bottle and sealed. After storage at 50°C for 1 month, the presence or absence of oil phase separation in the composition was visually confirmed, as indicated by the following criteria.

[0376] A: No change.

[0377] B: The oil phase is integrated, but a small amount of emulsion can be seen seeping to the surface.

[0378] C: Oil phase separation is visible.

[0379] Examples 1-39, Comparative Examples 1-24 (Preparation and Evaluation of the Compositions)

[0380] The components shown in Table 1 were prepared according to the proportions shown in Tables 2-7. Using a device where the agitator of a TKROBOMIX (Specialty Machinery Industry Co., Ltd.) machine was replaced with a TKHOMOMIXER MARKII 2.5 model, and the mixture was stirred at 8,000 rpm for 2 minutes, resulting in oil-in-water compositions for each example. The notations (A) to (D) in the tables correspond to components (A) to (D) in this specification, respectively, and (a) corresponds to liquid oily components outside the range of component (A) in this specification. Furthermore, the proportions shown in Tables 2-7 are the effective component amounts (mass %) of each component. The obtained compositions were evaluated using the methods described above. The results are shown in Tables 2-7.

[0381] [Table 1]

[0382] Table 1

[0383]

[0384] [Table 2]

[0385] Table 2

[0386]

[0387] [Table 3]

[0388] Table 3

[0389]

[0390] [Table 4]

[0391] Table 4

[0392]

[0393] [Table 5]

[0394] Table 5

[0395]

[0396]

[0397] [Table 7]

[0398] Table 7

[0399]

[0400] According to Tables 2 and 4-7, the compositions of the present invention (Examples 1-39) containing specific amounts of components (A) and (B) have a high repellency rate, excellent persistence of repellency effect, low odor intensity, and suppress odor originating from component (B) which is a fragrance with repellency effect, after 3 hours of application.

[0401] [Industry availability]

[0402] According to the present invention, a pest repellent composition that has excellent and sustained repellent effect on pests, especially flying pests, is safe, and suppresses strong odors derived from repellent fragrances, and is suitable for skin application can be provided; a pest retention inhibition composition; a pest repellent method; and a pest retention inhibition method.

Claims

1. A pest repellent composition, wherein, It contains the following components (A) and (B), and a tackifier as component (D), wherein the mass ratio of component (A) to component (B) (A) / (B) is 15 to 300. (A) A non-volatile liquid oily component selected from one or two of dimethylpolysiloxane, isopropyl myristate and squalane, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 60 mPa•s at 23°C as measured by a B-type rotational viscometer: ≥13% by mass and ≤99.95% by mass. (B) Selected from one or more spices from (B1) to (B5) and (B7) to (B9) below: 0.05% by mass or more, 3.5% by mass or less (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde. (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol. (B5)2-(4-methyl-2-thiazolyl)ethanol, (B7) Acetate (3-pentyloxetane-4-yl) ester, (B8) Dimethylphenethyl methanol acetate, (B9) Methyl anthranilate When component (A) is dimethylpolysiloxane, component (B) is one selected from (B1) to (B5) and (B7) to (B9), or component (B) is components (B1) and (B3). When component (A) is isopropyl myristate or squalane, component (B) is component (B1). When component (A) is selected from two of dimethylpolysiloxane, isopropyl myristate and squalane, component (B) is component (B1).

2. A composition for inhibiting pest retention, wherein, It contains the following ingredients (A) and (B), wherein the mass ratio of ingredient (A) to ingredient (B) (A) / (B) is 15 to 300. (A) A non-volatile liquid oily component selected from one or two of dimethylpolysiloxane, isopropyl myristate and squalane, with a surface tension of less than 40 mN / m at 25°C and a viscosity of less than 60 mPa•s at 23°C as measured by a B-type rotational viscometer: ≥13% by mass and ≤99.95% by mass. (B) Selected from one or more spices from (B1) to (B5) and (B7) to (B9) below: 0.05% by mass or more, 3.5% by mass or less (B1) One or more lactones selected from octahydro-2H-1-benzopyran-2-one, γ-decanolide, δ-decanolide, δ-nonanolide, and γ-undecanolide (B2) is selected from 9-ethylidene-3-oxatricyclo[6.2.1.0] 2,7 One or more ketones from undecane-4-one and octahydro-7-methyl-1,4-methylnaphthyl-6(2H)-one (B3) One or more aldehydes selected from 7-hydroxy-3,7-dimethyloctaldehyde and octahydro-5-methoxy-4,7-methylbridged-1H-indene-2-carboxaldehyde. (B4) Selected from one or more aromatic alcohols selected from phenethyl methyl ethyl methanol, cinnamyl alcohol, and eugenol. (B5)2-(4-methyl-2-thiazolyl)ethanol, (B7) Acetate (3-pentyloxetane-4-yl) ester, (B8) Dimethylphenethyl methanol acetate, (B9) Methyl anthranilate When component (A) is dimethylpolysiloxane, component (B) is one selected from (B1) to (B5) and (B7) to (B9), or component (B) is components (B1) and (B3). When component (A) is isopropyl myristate or squalane, component (B) is component (B1). When component (A) is selected from two of dimethylpolysiloxane, isopropyl myristate and squalane, component (B) is component (B1).

3. The composition according to claim 1 or 2, wherein, The content of component (A) is more than 13% by mass and less than 75% by mass.

4. A method for repelling pests, wherein, Apply the composition of claim 1 to the surface of human skin.

5. A method for inhibiting the persistence of pests, wherein, By attaching the composition of claim 2 to the limbs of the pest, the pest is prevented from remaining on human skin.

6. The composition according to claim 1 or 2, wherein, The surface tension of component (A) at 25°C is above 15 mN / m.

7. The composition according to claim 1 or 2, wherein, The viscosity of component (A) at 23°C, as measured using a type B rotational viscometer, is greater than 1 mPa•s.

8. The composition according to claim 1 or 2, wherein, The content of pest repellents other than component (A) and component (B) is less than 15% by mass.

9. The composition according to claim 1 or 2, wherein, It contains water as a component (C).

10. The composition of claim 9, wherein, The content of component (C) is more than 5% by mass and less than 86.95% by mass.

11. The composition of claim 9, wherein, The mass ratio of component (A) to component (C) (A) / (C) is between 0.05 and 10.

12. The composition of claim 9, wherein, It is an oil-in-water composition.

13. The composition according to claim 1 or 2, wherein, The content of component (D) is more than 0.01% by mass and less than 5% by mass.

14. The composition according to claim 1 or 2, wherein, Component (D) is a water-soluble cationic polymer, anionic polymer, nonionic polymer, amphoteric polymer, or bipolar polymer.

15. The composition according to claim 1 or 2, wherein, The content of component (A) is more than 20% by mass and less than 40% by mass.

16. The composition of claim 1 or 2, wherein, The surface tension of component (A) at 25°C is below 30 mN / m.

17. The composition of claim 9, wherein, The content of component (C) is 50% by mass or more.

18. The composition of claim 1 or 2, wherein, The content of component (D) is more than 0.1% by mass and less than 1% by mass.

19. The composition of claim 8, wherein, The pest repellent other than ingredient (A) and ingredient (B) is selected from one or more of DEET, icosardine, dimethyl phthalate, 2-ethyl-1,3-hexanediol, p-menthane-3,8-diol, caretane-3,4-diol, di-n-butyl succinate, hydroxyanisole, rotenone, ethyl 3-(acetylbutyl)aminopropionate, citronellol, eucalyptol, α-pinene, geraniol, citronellol, camphor, linalool, 2-undecone, citronellol oil, and lemongrass oil.

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