Suction device and suction method synchronized with pulse

Abstract

The present invention provides a suction device and method synchronized with the pulse, comprising: a suction pump, a suction pipeline and a pulse detection device; the pulse detection device is electrically connected to the controller of the suction pump, and the suction pump performs suction through the suction pipeline; the suction pump provides pulse pressure; the controller adjusts the pulse pressure according to the pulse signal detected by the pulse detection device, so that the pulse start time of the pulse pressure and the systolic pressure of the pulse are synchronized within a preset time error range. The present invention can detect the pulse of the object being sucked while suctioning, so that the pulse pressure of the suction is synchronized with the systolic pressure of the pulse, and an adjustable pulse negative pressure synchronized with the systolic pressure of the human blood vessels is superimposed on the set constant suction negative pressure, so as to improve the suction efficiency and reduce the excessive blood loss flow rate.

Description

Technical Field

[0001] The present invention relates to the field of medical equipment, and in particular to a suction device and a suction method synchronized with a pulse. Background Art

[0002] Thrombosis is a common clinical disease. The main hazards of thrombosis are: 1) thrombus blocking the blood vessel lumen, causing obstruction of distal blood return; 2) thrombus detachment, leading to serious hazards such as pulmonary embolism, cerebral embolism and myocardial infarction. Thrombus aspiration is a method of removing the thrombus by directly sucking the thrombus into the catheter under negative pressure. The advantages of catheter intervention for thrombus aspiration are (1) minimally invasive. Patients with high-risk embolism are in critical condition and often find it difficult to tolerate traditional open surgery. Relatively speaking, interventional treatment completes the catheter aspiration operation under local anesthesia, which is less invasive and has a faster recovery; (2) rapid effectiveness.

[0003] At present, the development of thrombus aspiration technology focuses on the following aspects:

[0004] 1. Aspiration catheter and overall system composition – The aspiration catheter overall system consists of a guide or balloon guide catheter, a delivery catheter and an aspiration catheter, an aspiration pump, a thrombus plaque collector and a thrombus plaque fragmentation device (US2019 / 0216476A1 – Penumbar Inc.)

[0005] 2. The suction catheter has two channels for suction and flushing. The control box is connected to the two channels of the catheter to complete the suction and flushing under synchronous control (US10944944B2-Boston Scientific Scimed Inc; US9332999B2-CovidientLP); thereby preventing the suction channel from being blocked and the need to remove the catheter to clear the thrombus plaque and reinsert the catheter.

[0006] 3. Place a strain gauge or differential pressure sensor on the suction catheter. The controller calculates the flow through the differential pressure to monitor whether the front end of the suction catheter is in contact with the clot. If there is no contact, the on-off valve in the suction link tube is automatically closed to stop suction. If the catheter is blocked, start pulsed suction (US6022747-Bayer CO; US16 / 977431-Penumbar Inc).

[0007] The amount of blood loss during thrombus aspiration is related to the pressure difference between the two ends of the catheter. The greater the pressure difference, the greater the suction force, and the higher the risk of excessive bleeding. At present, there is no good control method for how to improve the efficiency of thrombus aspiration and reduce the amount of blood loss. The efficiency of thrombus aspiration is considered to be the time it takes to complete the aspiration of the thrombus by overcoming the adhesion between the thrombus and the blood vessel wall under a certain suction pressure. Simulation calculations done by the industry have pointed out that when the adhesion between the thrombus and the blood vessel wall is 0.1N, for a 5cm long thrombus, when the suction negative pressure is -60Kpa (about 450mmHg), it takes about 120 seconds to complete the extraction of a 110cm suction catheter; for a 3cm long thrombus, if the suction negative pressure is -40Kpa (about 300mmHg), it takes about 100 seconds to complete the extraction of a 110cm suction catheter. If the adhesion between the thrombus and the blood vessel wall drops to 0.001N, for a 5cm long thrombus, it is still necessary to complete the suction within 100-140 seconds at a high suction negative pressure of -40kPa to -60Kpa (about 300-450mmHg); for a 3cm long thrombus, it is only necessary to complete the suction within 80-90 seconds at a suction negative pressure of -30kPa (about 225mmHg). Too high aspiration negative pressure is not suitable for actual clinical application; if a clinically acceptable suction negative pressure (between -30 and -40kPA) is selected, the low suction efficiency will lead to an increase in blood loss, and an increase in blood loss will cause a decrease in hemoglobin concentration. Summary of the invention

[0008] In view of the defects in the prior art, an object of the present invention is to provide a suction device and a suction method synchronized with the pulse.

[0009] A pulse-synchronized suction device according to the present invention comprises: a suction pump, a suction pipeline, and a pulse detection device;

[0010] The pulse detection device is electrically connected to a controller of the suction pump, and the suction pump performs suction through the suction pipeline;

[0011] The suction pump provides pulse pressure;

[0012] The controller adjusts the pulse pressure according to the pulse signal detected by the pulse detection device, so that the pulse start time of the pulse pressure and the systolic pressure of the pulse are synchronized within a preset time error range.

[0013] Preferably, the pulse pressure includes: a baseline pressure P0, and a pulse with a pressure variation of dP superimposed on the baseline pressure P0.

[0014] Preferably, the baseline pressure P0, the pressure variation and the duration T of the pulse are adjustable.

[0015] Preferably, the baseline pressure P0 and the pressure change dP are both negative pressures.

[0016] Preferably, the waveform of the pulse pressure includes a square wave, a triangle wave or is the same as a pulse signal.

[0017] Preferably, the pulse detection device includes: an electrocardiogram monitor, a blood pressure monitor, a pressure sensor, a flow rate sensor, a flow sensor or a micro-electromechanical system.

[0018] Preferably, a fluid flow rate sensor is provided in the suction pipeline;

[0019] When a flow rate slowdown is detected, it is determined that an object has been sucked into the suction pipeline;

[0020] The flow rate of the suction fluid is calculated according to the product of the flow velocity and the cross-sectional area of ​​the suction pipeline.

[0021] Preferably, the fluid flow rate sensor comprises: a heater, a first temperature sensor and a second temperature sensor;

[0022] There is a preset distance D between the first temperature sensor and the second temperature sensor, and the heater is arranged at the first temperature sensor or at a side of the first temperature sensor away from the second temperature sensor;

[0023] The heater heats the fluid to be measured to generate a temperature pulse for the first temperature sensor and the second temperature sensor to detect, thereby obtaining a time interval T between the first temperature sensor and the second temperature sensor detecting the temperature pulse;

[0024] The flow rate of the fluid V=D / T.

[0025] A pulse-synchronized suction method according to the present invention comprises the pulse-synchronized suction device;

[0026] Fixing the pulse detection device on the object to be sucked to obtain the pulse signal of the object to be sucked;

[0027] The baseline pressure and pulse variation of the pulse pressure sucked by the suction pump are set according to the object to be sucked;

[0028] The suction pump synchronizes the pulse start time of the pulse pressure and the systolic pressure of the pulse within a preset time error range according to the pulse signal.

[0029] Preferably, the method is used to aspirate thrombus;

[0030] A fluid flow rate sensor is provided in the suction pipeline;

[0031] When a slowing down of the flow rate is detected, it is determined that the thrombus has been sucked into the suction pipeline;

[0032] The flow rate of the aspirated blood is calculated according to the product of the flow rate and the cross-sectional area of ​​the aspiration pipeline, and the aspiration is stopped and a reminder is given when the flow rate exceeds a preset value.

[0033] Compared with the prior art, the present invention has the following beneficial effects:

[0034] The present invention can detect the pulse of the object being sucked while using pulse pressure for suction, so that the pulse pressure of suction is synchronized with the systolic pressure of the pulse, and an adjustable pulse negative pressure synchronized with the systolic pressure of human blood vessels is superimposed on the set constant suction negative pressure to improve the suction efficiency and reduce the excessive blood loss flow rate. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Other features, objects and advantages of the present invention will become more apparent from the detailed description of non-limiting embodiments made with reference to the following drawings:

[0036] Figure 1 It is a structural schematic diagram of the present invention;

[0037] Figure 2 It is the principle diagram of the present invention;

[0038] Figure 3 This is the schematic diagram of the fluid flow rate sensor. DETAILED DESCRIPTION

[0039] The present invention is described in detail below in conjunction with specific embodiments. The following embodiments will help those skilled in the art to further understand the present invention, but are not intended to limit the present invention in any form. It should be noted that, for those of ordinary skill in the art, several changes and improvements can also be made without departing from the concept of the present invention. These all belong to the protection scope of the present invention.

[0040] like Figure 1 As shown, the present invention provides a pulse-synchronized suction device, comprising: a suction pump 1, a suction pipeline 4, and a pulse detection device 2. The pulse detection device is electrically connected to a controller 3 of the suction pump, provides a working signal to the controller 3, and the suction pump performs suction through the suction pipeline 4.

[0041] The suction pump can provide pulse pressure, and the controller 3 adjusts the pulse pressure according to the pulse signal detected by the pulse detection device 2, so that the pulse start time of the pulse pressure and the systolic pressure of the pulse are synchronized within a preset time error range. In order to reduce the instantaneous suction force, improve the suction efficiency, and reduce the amount of blood loss under the same average suction force. The synchronization function can be selected when to apply according to the needs of the operation. The pulse detection device 2 includes but is not limited to pressure, flow rate, flow, micro-electromechanical system, temperature difference, photoplethysmography (PPG), ultrasound, electrocardiography, etc.

[0042] like Figure 2 As shown, since this embodiment is applied to the field of thrombus aspiration, negative pressure is required during aspiration. The pulse pressure includes: a baseline pressure P0, and a pulse with a pressure variation of dP superimposed on the baseline pressure P0, and the baseline pressure P0 and the pressure variation dP are both negative pressure. The baseline pressure P0, the pressure variation of the pulse and the duration T can be adjusted according to actual conditions.

[0043] At time t, the force for aspirating thrombus is formed by the pressure difference between the two ends of thrombus: BP(t)+P0+dP(t); BP is blood pressure, which is usually a function of positive pressure and time; P0 is the baseline pressure of the suction pump, which can be adjusted to a constant negative pressure (DC); dP is the pulsed negative pressure superimposed on P0, and its starting time is synchronized with the systolic pressure of BP(t) in the blood vessel. The shape of dP(t) can be controlled, such as proportional to BP(t), or it can be a square wave, a triangle wave, or the same as the pulse signal. Under the baseline pressure, the thrombus is static, and the thrombus is aspirated by the pulse pressure.

[0044] The present invention can arrange a fluid flow rate sensor in the suction pipeline. When the flow rate slows down, it is determined that an object has been sucked into the suction pipeline; and the flow rate of the suction fluid is calculated according to the product of the flow rate and the cross-sectional area of ​​the suction pipeline.

[0045] like Figure 3 As shown, the fluid flow rate sensor includes: a heater 22, a first temperature sensor 21 and a second temperature sensor 23. For ease of installation, the heater 22, the first temperature sensor 21 and the second temperature sensor 23 are arranged on the same substrate 24. There is a preset distance D between the first temperature sensor 21 and the second temperature sensor 23, and the heater 22 is arranged at the first temperature sensor 21 or at a side of the first temperature sensor 21 away from the second temperature sensor 23.

[0046] The working principle of the fluid flow rate sensor is as follows:

[0047] The heater 22 heats the temperature of the fluid to be measured, causing the fluid to generate a temperature pulse for detection by the first temperature sensor 21 and the second temperature sensor 23. Since the heater 22 is arranged at the first temperature sensor 21 or on the side of the first temperature sensor 21 away from the second temperature sensor 23, the first temperature sensor 21 will detect the temperature pulse earlier than the second temperature sensor 23, that is, the time interval T between the first temperature sensor 21 and the second temperature sensor 23 detecting the temperature pulse is obtained.

[0048] Thus we get:

[0049] The flow velocity V of the fluid to be measured is D / T, and the flow rate Q of the fluid to be measured is VA.

[0050] The first temperature sensor and the second temperature sensor of the present invention are both semiconductor sensors, such as MEMS sensors. Meanwhile, the fluid flow rate sensor is packaged in a sheet structure so as to be installed on the surface of the detection equipment or embedded in the pipeline.

[0051] The blood suction device can be used to suction thrombi and measure the blood flow velocity, flow rate and resistance in blood vessels or cavities, so as to control the blood loss during thrombus suction in real time, reduce the decrease in hemoglobin concentration caused by increased blood loss, and reduce the incidence of clinical adverse events of suction surgery.

[0052] The present invention also provides a method of suction synchronized with the pulse, including the above-mentioned suction device synchronized with the pulse. When in use, the pulse detection device is fixed on the object to be suctioned to obtain the pulse signal of the object to be suctioned. The baseline pressure and pulse change amount of the pulse pressure sucked by the suction pump are set according to the object to be suctioned. The suction pump synchronizes the pulse start time of the pulse pressure and the systolic pressure of the pulse according to the pulse signal. When a slowdown in the flow rate is detected, it is determined that the thrombus has been sucked into the suction pipeline; the flow rate of the sucked blood is calculated according to the product of the flow rate and the cross-sectional area of ​​the suction pipeline, and the suction is stopped and a reminder is given when the flow rate exceeds the preset value.

[0053] In the description of the present application, it should be understood that the terms "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0054] The above describes the specific embodiments of the present invention. It should be understood that the present invention is not limited to the above specific embodiments, and those skilled in the art can make various changes or modifications within the scope of the claims, which does not affect the essence of the present invention. In the absence of conflict, the embodiments of the present application and the features in the embodiments can be combined with each other arbitrarily.

Claims

1. A suction device synchronized with the pulse, characterized in that: include: Suction pump, suction pipeline and pulse detection device; The pulse detection device is electrically connected to a controller of the suction pump, and the suction pump performs suction through the suction pipeline; The suction pump provides pulse pressure; The controller adjusts the pulse pressure according to the pulse signal detected by the pulse detection device so that the pulse start time of the pulse pressure and the systolic pressure of the pulse are synchronized within a preset time error range; The pulse pressure includes: a baseline pressure P0, and a pulse with a pressure variation of dP superimposed on the baseline pressure P0; The baseline pressure P0, the pressure variation and duration of the pulse are adjustable; The baseline pressure P0 and the pressure change dP are both negative pressures; At time t, the force for aspirating the thrombus is formed by the pressure difference between the two ends of the thrombus: BP(t) + P0 + dP (t); Where BP is blood pressure, the onset time of pulse pressure is synchronized with the systolic BP (t) within the blood vessel.

2. The pulse-synchronized suction device according to claim 1, characterized in that: The waveform of the pulse pressure is a square wave, a triangle wave or a waveform identical to the pulse signal.

3. The pulse-synchronized suction device according to claim 1, characterized in that: The pulse detection device includes: an electrocardiogram monitor, a blood pressure monitor, a pressure sensor, a flow velocity sensor, a photoelectric volumetric pulse wave graph, ultrasound, a flow sensor or a micro-electromechanical system.

4. The pulse-synchronized suction device according to claim 1, characterized in that: A fluid flow rate sensor is provided in the suction pipeline; When a flow rate slowdown is detected, it is determined that an object has been sucked into the suction pipeline; The flow rate of the suction fluid is calculated according to the product of the flow velocity and the cross-sectional area of ​​the suction pipeline.

5. The pulse-synchronized suction device according to claim 4, characterized in that: The fluid flow rate sensor comprises: a heater, a first temperature sensor and a second temperature sensor; There is a preset distance D between the first temperature sensor and the second temperature sensor, and the heater is arranged at the first temperature sensor or at a side of the first temperature sensor away from the second temperature sensor; The heater heats the fluid to be measured to generate a temperature pulse for the first temperature sensor and the second temperature sensor to detect, thereby obtaining a time interval T between the first temperature sensor and the second temperature sensor detecting the temperature pulse; The flow rate of the fluid V= D / T.

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