Internal securing device for equipment in transport mode, equipment and method for reducing damage to equipment during transport

Abstract

The application relates to an internal fixing device of equipment in a transportation mode, equipment with the device and a method for reducing the damage risk of the equipment in transportation. The internal fixing device comprises a limiting device, an eccentric roller transmission assembly, a motor assembly, a motion guide assembly and the like. The output shafts of the motors are fixedly arranged on the eccentric wheel transmission assemblies on the two sides of the equipment. After the transportation mode, the eccentric wheel and the handle are self-locked and the motion is stopped by triggering the microswitch on the limiting device. The application can effectively reduce the damage risk of the equipment in transportation.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of internal fixation of equipment, in particular to an internal fixation device of equipment during transportation, and a method for reducing damage of equipment during transportation, and more particularly to an internal fixation device of nucleic acid analyzer, and a method for reducing damage of nucleic acid analyzer during transportation. BACKGROUND

[0002] The principle of PCR technology is similar to the natural replication process of DNA, and its specificity depends on the complementary oligonucleotide primers at both ends of the target sequence, which consists of three basic reaction steps of denaturation, annealing and extension. RT-PCR technology is formed by combining RNA reverse transcription and PCR. Based on the development of PCR and RT-PCR detection technology, various nucleic acid detection methods such as fluorescent PCR, DNA sequencing and RNA sequencing have emerged, which have high sensitivity and high specificity, and have been widely used in human and animal disease diagnosis (such as prenatal diagnosis, neonatal screening and genetic metabolic disease detection), forensic detection, kinship analysis, seed purity identification, molecular marker assisted breeding, gene mapping and transgenic organism detection, etc.

[0003] Both PCR and RT-PCR are carried out in a PCR analyzer. As a device for amplifying specific DNA or RNA, the PCR instrument mainly includes a sample cabin, a hot cover module and a control module. The PCR instrument for fluorescent PCR detection (also known as fluorescent PCR instrument) also includes an optical detection module, which can use an excitation light source to irradiate the reaction tube in the PCR / RT-PCR amplification reaction, excite the fluorescent dye or the probe containing the fluorescent group (such as TaqMan or MGB probe, double hybridization probe or molecular beacon probe, etc.) to emit fluorescence, and detect the generated fluorescence signal, and use the fluorescence signal accumulation to monitor the whole PCR / RT-PCR reaction process in real time, and qualitatively or quantitatively determine the possible DNA or RNA in the clinical sample.

[0004] When the PCR instrument is in working mode, the test tube rack or test tube holder in the thermal cycling module is connected with the thermal cover module under the drive of the moving mechanism, and the PCR reagents (including DNA polymerase, at least one pair of amplification primers, magnesium ions, dNTPs, etc., and preferably at least one probe containing a fluorescent group, and if RNA is amplified, a reverse transcriptase) in the test tube and the extracted sample nucleic acid perform multiple rounds of nucleic acid amplification reactions. For example, Chinese patent CN2218181Y discloses that the test tube rack is connected with the transmission device installed on the test tube holder to drive the test tube rack to move up and down, the test tube holder is installed on the horizontal guide rail of the rack and connected with the driving device to drive it to move horizontally, and the transmission device is a crank slider mechanism or an eccentric wheel mechanism and is connected with the motor installed on the test tube holder. However, this patent has the problem that during transportation, even if the motor is not turned on, the crank slider mechanism or the eccentric wheel mechanism will shake or vibrate, or even swing greatly, which will cause the test tube rack to be unable to be fixed and collide with other adjacent components and be damaged, and as a result, it may not be able to continue to be used, even if it can be used, the service life will be greatly shortened. Secondly, the motor not only controls the transmission device to drive the test tube rack to move up and down, but also controls the driving device to drive the test tube holder to move horizontally, which makes the control of the movement of the test tube rack more complicated. Furthermore, during transportation, the motor may be started during the shaking or collision of the PCR instrument, causing the transmission device and the driving device to operate, and there is no remedy to stop the motor from operating.

[0005] Chinese patent CN105039155B discloses that the transmission nut drives the thermal cover support fixed thereon to move up and down, thereby driving the thermal cover to move up and down, when the thermal cover moves downward, the test tube rack is pressed down, which in turn drives the connecting support to press the spring, so that the sample on the test tube rack enters the detection module for analysis, after the analysis is completed, the connecting support is automatically returned under the drive of the spring, thereby driving the test tube rack to separate from the detection module. This patent also has the problem that the test tube rack and the thermal cover support and other components shake or vibrate during transportation.

[0006] Therefore, it is necessary to provide a solution to reduce the damage of the instrument during transportation. SUMMARY

[0007] One of the purposes of the present application is to provide an internal fixing device for a device in a transportation mode, which comprises a motor, a transmission device, a limiting device and a micro switch, the motor comprises a motor output shaft, the transmission device comprises an eccentric roller, a roller output shaft, a handle, a shaft shoulder screw and a guide rail, the motor output shaft is fixedly connected with the eccentric roller, the eccentric roller is movably connected with the handle through the roller output shaft, the handle is movably connected with the guide rail through the shaft shoulder screw, and the handle can move up and down relative to the guide rail and swing clockwise and counterclockwise relative to the shaft shoulder screw; the limiting device is arranged near the end of the handle, and when the handle is in a vertical state, the limiting device is at a proper distance from the end of the handle; the device comprises a transportation mode, when the device is in the transportation mode, the handle triggers the micro switch, the motor stops running, and the limiting device prevents the handle from moving.

[0008] As a further improvement, the internal fixing device comprises two transmission devices arranged on both sides of the device respectively, and the two ends of the motor output shaft are fixed to the eccentric rollers of the two transmission devices respectively.

[0009] As a further improvement, the internal fixing device further comprises a sliding groove movably connected with the shaft shoulder screw, and the sliding groove is slidably connected with the guide rail.

[0010] As a further improvement, the internal fixing device is provided with at least two optical coupling switches near the eccentric roller respectively, for controlling the opening and closing of the motor.

[0011] As a further improvement, the motor is a direct current motor.

[0012] The second purpose of the present application is to provide a detection analyzer, which comprises a support frame and a motion system fixed to the support frame, the motion system comprises a motor, a motor output shaft connected with the motor, an eccentric roller fixedly connected with the motor output shaft, a handle movably connected with the eccentric roller, and a guide rail movably connected with the handle; the handle can move up and down relative to the guide rail and swing clockwise and counterclockwise relative to the connecting point of the handle and the guide rail; a limiting device and a micro switch are arranged near the end of the handle, and when the handle is in a vertical state, the end of the handle is at a proper distance from the limiting device; when the handle triggers the micro switch, the motor stops running, and the limiting device abuts against the end of the handle.

[0013] As a further improvement, the motion system comprises two eccentric rollers, two handles and two guide rails, the two eccentric rollers are fixedly connected with the two ends of the motor output shaft respectively, and each eccentric roller is movably connected with the corresponding handle and guide rail in turn.

[0014] As a further improvement, the connecting point of the handle and the guide rail is located in the middle of the handle, and the handle is movably connected with the guide rail through a sliding groove.

[0015] As a further improvement, the detection analyzer is a nucleic acid detection analyzer.

[0016] As a further improvement, the detection analyzer further comprises a position recognition system, including a position recognition device judging the position of the sample cabin in the standby mode, a position recognition device judging the position of the sample cabin in the working mode and a position recognition device judging the position of the sample cabin in the transportation mode.

[0017] As a further improvement, the motor is a direct current motor.

[0018] The third object of the present application is to provide a detection analyzer, comprising a support frame and a motion system fixed to the support frame, the motion system comprising a motor, a motor output shaft connected with the motor, an eccentric roller fixedly connected with the motor output shaft, a handle movably connected with the eccentric roller and a guide rail movably connected with the handle; the detection analyzer comprises at least three modes: standby mode, working mode and transportation mode, wherein when the detection analyzer is in the transportation mode, the motor, the motor output shaft, the eccentric roller, the handle and the guide rail form a self-locking state and cannot move relative to each other.

[0019] As a further improvement, the handle can move up and down relative to the guide rail and can swing clockwise and counterclockwise relative to the connection point between the handle and the guide rail.

[0020] As a further improvement, a limiting device and a micro switch are arranged near the end of the handle, when the handle is in a vertical state, the end of the handle is spaced apart from the limiting device by a proper distance, when the handle triggers the micro switch, the motor stops running, and the limiting device abuts against the end of the handle.

[0021] As a further improvement, the motion system comprises two eccentric rollers, two handles and two guide rails, the two eccentric rollers are fixedly connected with the two ends of the motor output shaft respectively, and each eccentric roller is movably connected with the corresponding handle and guide rail in sequence.

[0022] As a further improvement, the connection point between the handle and the guide rail is located in the middle of the handle, and the handle is movably connected with the guide rail via a sliding groove.

[0023] As a further improvement, the motor is a direct current motor.

[0024] The fourth object of the present application is to provide a method for reducing damage to the equipment during transportation, which comprises providing an equipment comprising a support frame and a motion system fixed to the support frame, the motion system comprising a motor, a motor output shaft connected to the motor, an eccentric roller fixedly connected to the motor output shaft, a handle movably connected to the eccentric roller, and a guide rail movably connected to the handle; a limiting device and a micro switch are provided near the end of the handle, and there is a proper distance between the limiting device and the end of the handle when the handle is in a vertical state; the equipment comprises a transportation mode; the equipment is set to the transportation mode, the handle triggers the micro switch, the motor stops running, the limiting device prevents the handle from moving, and the motor, the motor output shaft, the eccentric roller, the handle, and the guide rail form a self-locking state and cannot move relative to each other.

[0025] As a further improvement, a working mode is also included, and when the equipment is set to the working mode, the handle is separated from the micro switch, the equipment is unlocked, and the handle moves up and down relative to the guide rail and swings clockwise and counterclockwise relative to the connection point of the handle and the guide rail.

[0026] As a further improvement, the motion system comprises two eccentric rollers, two handles, and two guide rails, and the two eccentric rollers are fixedly connected to the two ends of the motor output shaft, respectively, and each eccentric roller is movably connected to the corresponding handle and guide rail in turn.

[0027] As a further improvement, the connection point of the handle and the guide rail is located in the middle of the handle, and the handle is movably connected to the guide rail through a sliding groove.

[0028] As a further improvement, the motor is a DC motor.

[0029] The nucleic acid detection analyzer of the application can be provided with standby mode, working mode and transportation mode. When the instrument is in standby mode, the sample cabin is in the lowest position, and the sample cabin can be pulled out manually (or controlled by electricity). There are multi-well test tube seats in the sample cabin, and test tubes containing experimental reagents can be placed in the test tube seats. The handle in the eccentric roller assembly is out of contact with the micro switch installed on the limit block. When the instrument is in the working experiment state, the sample cabin rises to the highest position to form a PCR amplification system with the hot cover installed on the transmission platform base, and the temperature control process of the predetermined temperature curve is completed. The handle in the eccentric roller assembly is out of contact with the micro switch installed on the limit block. When the instrument is in the transportation mode state, in order to prevent the sample cabin from shaking and ensure the reliability of transportation, the sample cabin needs to be fixed. When the instrument starts the transportation mode, the sample instrument is placed in the 4-row 8-link pipe when the sample instrument is in the lowest position, the DC motor rotates, and the sample cabin is vertically lifted to the working position at the highest position through motion conversion. At this time, the spring inside the sample cabin is compressed, and the spring pressure tightly contacts the sample cabin and the transmission platform base. The motor continues to move, and the handle in the right eccentric roller assembly continues to swing until the micro switch on the limit block is triggered, and the output signal makes the DC motor stop working. At this time, the sample cabin reaches the transportation position, and the instrument is in the transportation mode. The spring inside the sample cabin is still in the compressed state, providing sufficient spring pressure to ensure that the sample cabin is in a stable fixed state.

[0030] When the instrument is subjected to external vertical vibration or impact during transportation, the sample cabin will not pass the upper dead point of the transmission mechanism under the combined action of the internal spring pressure and the downward impact force, causing the motor to reverse, so that the sample cabin is in an unfixed state. At the same time, the limit device further prevents the motor from continuing to rotate forward due to external force, so that the sample cabin is always in a stable fixed state.

[0031] The beneficial effects of the application are: the motion principle of the application is: the motor drives two eccentric roller assemblies through the motor output shaft, converting the circular motion of the motor into left and right swinging of the handle in the left and right eccentric roller assemblies, and the guide rail slides up and down in the sliding groove. The guide rail is located on both sides of the sample cabin of the equipment. With the up and down reciprocating motion of the guide rail, the sample cabin is in standby mode, working mode or transportation mode, as shown in Figure 14

[0032] Under the cooperation of the eccentric roller assembly, the motor assembly, the micro switch and the limit block, when subjected to external vertical vibration or impact during transportation, the above components form a self-locking together, and the components cannot move relative to each other, thereby avoiding the reverse rotation or continuous rotation of the motor, so that the sample cabin is in an unfixed state and displacement occurs. Therefore, it is ensured that the sample cabin of the fluorescent quantitative PCR instrument is always in a fixed position during transportation, reducing the probability and degree of damage of the instrument during transportation, and thereby protecting the instrument well.​ Attached Figure Description

[0033] Figure 1 This is a diagram of standby mode.

[0034] Figure 2 This is the internal front view in standby mode.

[0035] Figure 3 This is the internal rear view in standby mode.

[0036] Figure 4 This is the internal side view in standby mode.

[0037] Figure 5 This is a schematic diagram of the working mode.

[0038] Figure 6 This is the internal front view in working mode.

[0039] Figure 7 This is the internal rear view in working mode.

[0040] Figure 8 This is the internal working mode.

[0041] Figure 9 This is a diagram illustrating transportation modes.

[0042] Figure 10 This is the internal front view in the transportation mode.

[0043] Figure 11 This is the interior rear view in transport mode.

[0044] Figure 12 This is the internal side view in transport mode.

[0045] Figure 13 This is a schematic diagram of the internal structure of a nucleic acid detection analyzer.

[0046] Figure 14 It is a diagram illustrating the principle of motion. Detailed Implementation

[0047] like Figure 1 and 14The device shown in the transport mode inside the fixing device, including motor 121, transmission device 110, limiting device 140 and micro switch 213. Two transmission devices 110 are respectively arranged on both sides of the device, and the transmission device 110 includes eccentric roller 111, crank 112 and guide rail 131. The motor 121 includes the motor output shaft 122, and the two ends of the motor output shaft 122 are respectively fixedly connected with the left and right eccentric rollers 111. Each eccentric roller 111 is respectively connected with the corresponding crank 112 through the roller output shaft 114, and the crank 112 is connected with the corresponding guide rail 131 through the shaft shoulder screw 115. The fixed connection described in the patent refers to the relative displacement and rotation between the connected components, which can only be a whole relative displacement or rotation. The active connection described in the patent refers to the relative displacement or rotation of the connected components, which can also be relative displacement or rotation between each other. The limiting device 140 is arranged near the end of one of the cranks 112, and when the transmission device 110 is at the upper dead point, the crank 112 is in the vertical state, and the end of the crank 112 and the limiting device 140 have a proper distance, which ensures that the crank can swing from the upper dead point to the limiting device, and the limiting device can prevent the motor from continuing to rotate due to external force, so that the device is in a stable self-locking state. In one embodiment, the micro switch 213 is arranged near the end of the limiting device and the crank 112, or directly arranged on the limiting device 140. When the crank 112 reaches the upper dead point and continues to swing until the micro switch 213 is triggered, the motor 121 stops rotating. The micro switch 213 can also not be installed on the limiting device 140, but between the limiting device 140 and the crank 112. The device of the fixing instrument also includes a sliding groove 132 (as shown in Figure 13

[0048] As Figures 1 to 13 The nucleic acid detection analyzer shown in the figure includes a motion system, a sample cabin 300, an optical system and a support frame 700.

[0049] The sample cabin 300 includes a sample block (not shown in the figure) storing test tubes 310, a thermal cycle device, a fan mounting plate 330, and a lower supporting plate 340 connected with the guide rail 131.

[0050] ​A spring 350 is arranged between the fan mounting plate 330 and the lower supporting plate 340. The spring guide column 351 is arranged at the bottom of the fan mounting plate 330 and is sleeved in the spring 350. The lower supporting plate 340 is provided with a hole for the spring guide column 351 to pass through. When the lower supporting plate 340 moves upward, the spring 350 placed on the lower supporting plate 340 is pushed to move upward, and the spring 350 pushes the fan mounting plate 330 arranged thereon to move upward, until the sample chamber 300 rises to the highest position, and the test tube 310 abuts against the bracket platform 710. At this time, the motor 121 stops rotating, and the nucleic acid detection analyzer enters the working mode to complete the temperature control process of the predetermined temperature curve and the detection of the PCR reaction process. In one scheme, a heat cover is arranged above the sample chamber. The thermal cycle device includes a heat sink 320 and a Peltier element (not shown).

[0051] Two transmission devices are arranged on the two sides of the sample chamber 300, and each transmission device includes an eccentric roller 111, a handle 112 and a guide rail 131. The two ends of the motor output shaft 122 are fixed on the eccentric rollers 111 on the left and right sides, the eccentric rollers 111 are movably connected to the handle 112 through a roller output shaft 114, the guide rail 131 is movably connected to the handle 112 through a shaft shoulder screw 115 and is in sliding fit with a sliding groove 132. The limiting device 140 is arranged on the right side of the bracket 700 and is located on the left side of the handle 112 when the transmission device is at the upper dead point. The limiting device 140 is arranged at a proper distance from the handle 112 in this state, which ensures that when the handle 112 swings from the upper dead point to the limiting device 140, the limiting device 140 can prevent the motor 121 from continuing to rotate in the positive direction due to external force, so that the sample chamber 300 is in a stable self-locking state in the transportation mode. The micro switch 213 is arranged on the limiting device 140, and when the handle 112 reaches the upper dead point and continues to swing to trigger the micro switch 213, the motor 121 stops rotating.

[0052] The motor 121 is preferably a direct current motor. The two ends of the motor output shaft 122 are fixedly connected to the eccentric rollers 111 on the two sides of the device, and the circumferential periodic motion of the motor 121 is converted into the up-down linear motion of the sample chamber 300.

[0053] The motor 121, the fan mounting plate 330, the lower supporting plate 340, the spring 350 and the bracket platform 710 jointly constitute the up-down transmission and force applying device of the analyzer.

[0054] The nucleic acid detection analyzer is in different states, such as standby state, working state of running detection and transportation mode, according to the use of the analyzer. The sample cabin is in different positions in the analyzer in different states of the analyzer. In the standby state of the analyzer, the sample cabin is in its lower position in the analyzer. In the working state of the analyzer, the sample cabin is in its higher position in the analyzer. In the transportation of the nucleic acid detection analyzer, the position of the sample cabin in the analyzer is slightly lower than that in the working mode, but higher than that in the standby state.

[0055] In order to determine the state of the analyzer, the nucleic acid detection analyzer is also provided with a position recognition system 200 to determine the position of the sample cabin in the analyzer. The recognition system includes a first optocoupler switch 211 to determine the sample cabin in the standby mode, a second optocoupler switch 212 to determine the sample cabin in the working mode and a micro switch 213 to determine the sample cabin in the transportation mode. The first optocoupler switch 211 and the second optocoupler switch 212 are installed on the support frame and located on the left and right sides of the eccentric roller respectively. After the eccentric roller rotates to lift the handle to the highest position, the eccentric roller continues to rotate in the same direction. The micro switch 213 is arranged in the direction in which the handle continues to swing and deviates from the vertical position of the handle. The position recognition device includes but is not limited to optocoupler switch, micro switch, position sensing switch and the like.

[0056] As shown in Figures 1 to 4 , when the analyzer selects the standby mode, the handle and the roller output shaft 114 of the eccentric roller are in the lowest position, and at this time the blocking strip 113 just blocks the light path of the first optocoupler switch 211. The control system of the analyzer obtains the signal that the light path of the first optocoupler switch is not open, the motor does not rotate, and the detection system does not run.

[0057] As shown in Figures 5 to 8 , when the analyzer selects the working mode, the control system of the analyzer starts the motor 121 to run, the motor rotates forward, the circular motion of the motor drives the eccentric roller 111 to rotate clockwise, and the handle 112 swings. The guide rail 131 moves upward in the sliding groove 132 with the swinging of the handle. The lower supporting plate 340 moves upward synchronously with the guide rail. The lower supporting plate 340 pushes the spring 350 installed thereon to move upward, and the spring in turn pushes the fan mounting plate 330 in contact with it to move upward to the highest position of the sample cabin, and the test tube in the sample block pushes against the support platform, and the support platform has a downward pressure on the sample cabin. The downward pressure of the support platform on the sample cabin and the spring pressure make the sample cabin stably keep in the working position. Specifically, the eccentric roller rotates 90 degrees clockwise from the standby mode, and the upper segment of the handle swings to the right side first. The eccentric roller further rotates 90 degrees clockwise, and the upper segment of the handle swings to the left side. When the transmission device is at the upper dead point, the blocking strip 113 just blocks the second optocoupler switch 212. The control system of the analyzer obtains the information that the light path of the second optocoupler switch is not open, stops the motor from running, and starts the detection.

[0058] To prevent the sample chamber from shaking and ensure reliable transportation, the sample chamber needs to be secured during transport. For example... Figures 9 to 12 As shown, when the analyzer selects the transport mode, the control system first positions the sample compartment in the standby state, placing an appropriate number of empty test tubes 310 (e.g., 4 rows of 8-tube strips) inside. Then, the motor is started, and as the motor rotates, the sample compartment rises vertically to the working position. At this point, the spring 350 between the lower support plate and the fan mounting plate is compressed. The motor continues to rotate forward, and the crank handle swings after passing the top dead center and touches the microswitch 213, triggering the microswitch. After receiving the microswitch trigger signal, the control system stops rotating. Because the crank handle does not deviate significantly from the top dead center, the spring between the lower support plate and the fan mounting plate remains compressed, and sufficient spring pressure ensures the sample compartment remains in a stable, fixed position.

[0059] When the analyzer is in transport mode, the motor is stopped, and the eccentric roller cannot continue to rotate clockwise or counterclockwise by means of the motor's rotation. If the equipment is subjected to external vertical vibration or impact during transport, the line of action of the vertical force on the eccentric roller assembly fixed by this device will not deviate from the top dead center position. This prevents torque from being generated under the combined action of internal spring pressure and downward impact force, thus avoiding the motor reversing or continuing to rotate. This ensures the instrument remains in a fixed position during transport, avoiding the risk of damage during transport.

[0060] During transportation, external vertical vibrations or impacts may cause the crank handle to unexpectedly swing further to the left in the transport mode position until the internal spring loses pressure, causing the sample compartment to become unsecured and displaced. However, due to the limiting device, this unexpected swing of the crank handle will not occur. Furthermore, without lifting force, the crank handle will not reverse to the right to its highest position and continue reversing until the internal spring loses pressure. This ensures the sample compartment remains in a stable, fixed position. The location of the limiting device on either side of the crank handle can be adjusted according to the actual design.

[0061] The control system of the nucleic acid detection analyzer changes the positive and negative poles of the direct current motor, reverses the motor, and the circular motion of the motor drives the eccentric roller 111 to rotate counterclockwise, and the swing handle 112 connected with the eccentric roller swings. The guide rail 131 swings in the sliding groove 132 and moves downward. The lower supporting plate moves downward synchronously under the driving of the guide rail. The spring installed on the lower supporting plate moves downward, and the test tube seat moves downward synchronously until the sample cabin returns to the standby mode position. Specifically, the eccentric roller rotates counterclockwise by 90 degrees from the working mode position or the transportation mode position, and the upper segment of the swing handle swings to the right side. The eccentric roller further rotates clockwise by 90 degrees, and the upper segment of the swing handle swings to the left side. Until the blocking strip 113 blocks the first optocoupler switch 212 again. The analyzer control system obtains the data that the light path of the first optocoupler switch is not open, determines that the sample cabin has returned to the standby mode position, and stops the motor from rotating.

[0062] The optical system of the nucleic acid analyzer includes a light source and a detector (such as a photomultiplier tube), the excitation light generated by the light source can excite the fluorescent dye or the probe carrying the fluorescent group in the test tube to generate fluorescence, and the generated fluorescence can be detected by the detector. The thermal cycling module of the analyzer can heat and cool the test tube seat, so that the reaction reagent in the test tube circulates between the denaturation temperature, the annealing temperature and the extension temperature.

[0063] The "up", "down", "left", "right", "clockwise", "counterclockwise" and other orientation words related to the present application are the relative positions between components, not the absolute spatial positions, and are not the limitation of the present application.

Claims

1. An internal fixture for a device in a transport mode, characterized by: The device comprises a motor, a transmission device, a limiting device and a micro switch, the motor comprises a motor output shaft, the transmission device comprises an eccentric roller, a roller output shaft, a handle, a shaft shoulder screw and a guide rail, the motor output shaft is fixedly connected with the eccentric roller, the eccentric roller is movably connected with the handle through the roller output shaft, the handle is movably connected with the guide rail through the shaft shoulder screw, and the handle can move up and down relative to the guide rail and swing clockwise and counterclockwise relative to the shaft shoulder screw; the limiting device is arranged near the end of the handle, and there is a proper distance between the limiting device and the end of the handle when the handle is in a vertical state; the device comprises a transportation mode, when the device is in the transportation mode, the handle triggers the micro switch, the motor stops running, the limiting device prevents the handle from moving, and the limiting device prevents the motor from continuing to rotate forward due to external force, so that the device is in a stable self-locking state.

2. The internal fixation device according to claim 1, wherein: The device comprises two transmission devices arranged on the two sides of the device respectively, and the two ends of the motor output shaft are fixed to the eccentric rollers of the two transmission devices respectively.

3. The internal fixation device according to claim 2, wherein: The device further comprises a sliding groove movably connected with the shaft shoulder screw, and the sliding groove is slidably connected with the guide rail.

4. The internal fixation device according to claim 3, wherein: At least two optical coupler switches are arranged near the eccentric rollers respectively, for controlling the start and stop of the motor.

5. A detection analyzer comprising a support frame and a motion system fixed to the support frame, characterized in that: The movement system comprises a motor, a motor output shaft connected with the motor, an eccentric roller fixedly connected with the motor output shaft, a handle movably connected with the eccentric roller, and a guide rail movably connected with the handle; the handle can move up and down relative to the guide rail and swing clockwise and counterclockwise relative to the connecting point of the handle and the guide rail; a limiting device and a micro switch are arranged near the end of the handle, and the end of the handle is spaced apart from the limiting device by a proper distance when the handle is in a vertical state; when the handle triggers the micro switch, the motor stops running, the limiting device abuts against the end of the handle to prevent the handle from moving, and the limiting device prevents the motor from continuing to rotate forward due to external force, so that the device is in a stable self-locking state.

6. The detection analyzer of claim 5, wherein: The movement system comprises two eccentric rollers, two handles and two guide rails, the two eccentric rollers are fixedly connected with the two ends of the motor output shaft respectively, and each eccentric roller is movably connected with a corresponding handle and guide rail in sequence.

7. The detection analyzer of claim 6, wherein: The connecting point of the handle and the guide rail is located in the middle of the handle, and the handle is movably connected with the guide rail through a sliding groove.

8. The detection analyzer of claim 7, wherein: The detection analyzer is a nucleic acid detection analyzer.

9. A detection analysis apparatus characterized by comprising: The detection analyzer comprises the detection analyzer of any one of claims 5-8, and the detection analyzer comprises at least three modes: a standby mode, a working mode and a transportation mode; when the detection analyzer is in the transportation mode, the motor, the motor output shaft, the eccentric roller, the handle and the guide rail form a self-locking state and cannot move relative to each other, the handle triggers the micro switch, the motor stops running, the limiting device prevents the handle from moving, and the limiting device prevents the motor from continuing to rotate forward due to external force, so that the device is in a stable self-locking state.

10. The detection assay device of claim 9, wherein: The device further comprises a sample cabin and a sample cabin position recognition system, and the sample cabin position recognition system comprises a position recognition device for judging the position of the sample cabin in the standby mode, a position recognition device for judging the position of the sample cabin in the working mode and a position recognition device for judging the position of the sample cabin in the transportation mode.

11. The detection assay device of claim 9, wherein: The motor is a direct current motor.

12. A method of reducing damage to equipment when in transit, characterized by: The device comprises a support frame and a motion system fixed to the support frame, the motion system comprising a motor, a motor output shaft connected with the motor, an eccentric roller fixedly connected with the motor output shaft, a rocking handle movably connected with the eccentric roller, and a guide rail movably connected with the rocking handle; a limiting device and a micro switch are arranged near the end of the rocking handle, and the limiting device has a proper distance from the end of the rocking handle when the rocking handle is in a vertical state; the device comprises a transportation mode; when the device is set to the transportation mode, the rocking handle triggers the micro switch, the motor stops running, the limiting device prevents the rocking handle from moving, the motor, the motor output shaft, the eccentric roller, the rocking handle and the guide rail form a self-locking state in which they cannot move relative to each other, the rocking handle triggers the micro switch, the motor stops running, the limiting device prevents the rocking handle from moving, and the limiting device prevents the motor from continuing to rotate in a positive direction due to external force, so that the device is in a stable self-locking state.

13. The method of claim 12, wherein: The device also comprises a working mode; when the device is set to the working mode, the rocking handle is separated from the micro switch, the device is released from the self-locking state, and the rocking handle moves up and down relative to the guide rail and swings clockwise and counterclockwise relative to the connecting point of the rocking handle and the guide rail.

14. The method of claim 13, wherein: The motion system comprises two eccentric rollers, two rocking handles and two guide rails, the two eccentric rollers are fixedly connected with the two ends of the motor output shaft respectively, and each eccentric roller is movably connected with a corresponding rocking handle and guide rail in sequence.

15. The method of claim 14, wherein: The connecting point of the rocking handle and the guide rail is located in the middle of the rocking handle, and the rocking handle is movably connected with the guide rail via a sliding groove.

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