Fully automatic protein analysis system

Abstract

A fully automatic protein analysis system comprises: an analysis module, comprising a detection component and a rotatable reaction disk, the reaction disk is provided with a plurality of reaction vessels distributed in a circumferential direction, and the detection component is arranged opposite to the reaction vessels; a sampling module, comprising a rotating first sampler and a rotatable sample disk, the sample disk is provided with a plurality of sample vessels, and the sampler is used to absorb samples in the sample vessels and discharge them into the reaction vessels; a dilution module, comprising a dilution disk for storing diluent, a rotating second sampler and a rotatable mixing disk, the mixing disk is provided with a plurality of mixing vessels, the dilution disk and the mixing vessels are located on the rotation path of the second sampler, and the mixing vessels are located on the rotation path of the first sampler; a reagent taking module, comprising a reagent taking device and a rotatable reagent disk, the reagent disk is provided with a plurality of reagent vessels, thereby effectively improving the culture detection efficiency of the whole machine and having good practicality.

Description

Technical Field

[0001] The present invention relates to the technical field of cell protein analysis, and in particular to a fully automatic protein analysis system. Background Art

[0002] The detection and analysis of specific proteins has important clinical significance for disease diagnosis. Currently, the most commonly used detection principle is immunoturbidimetry. Over thousands of plasma proteins have been discovered, with hundreds of the more important ones varying in size and content, each performing distinct functions. Clinically, dozens of plasma proteins are commonly used. These proteins possess strong antigenicity and can bind to antibody molecules with corresponding antigenic determinants. They can be found in body fluids such as blood, cerebrospinal fluid, and urine. These proteins are referred to as "specific proteins," and their quantitative detection provides an important basis for clinical diagnosis, therapeutic efficacy assessment, and prognosis analysis.

[0003] Due to the development of protein detection technology and the expansion of its clinical application, immunoturbidimetric analyzers have become a common clinical testing equipment purchased by domestic laboratories in recent years. In this type of analyzer, the method of adding samples and reagents to a reaction dish on a rotatable reaction vessel via a sample needle, and then measuring the absorbance of the reaction liquid in the reaction dish via a light detector is becoming increasingly mainstream. However, in actual use, specific proteins in some reaction dishes can be detected directly after adding reagents, while specific proteins in other reaction dishes may need to be pre-treated by dilution or initial incubation before subsequent reagent addition and detection. This results in low detection efficiency of specific proteins in the reaction vessel, which in turn affects the automated analysis efficiency of the entire machine. Summary of the Invention

[0004] The problem solved by the present invention is to provide a fully automatic protein analysis system which can realize fully automatic detection and analysis of specific proteins and has high analysis efficiency.

[0005] To solve the above problems, the present invention provides a fully automatic protein analysis system having:

[0006] The analysis module includes a detection assembly and a rotatable reaction disk, wherein the reaction disk is provided with a plurality of reaction vessels distributed along a circumference, the detection assembly includes at least one of a transmission light detector and a scattered light detector, and the detection assembly is disposed directly opposite the reaction vessels;

[0007] The sampling module includes a first rotary sampler and a rotatable sample tray, wherein the sample tray is provided with a plurality of sample dishes, wherein the sample dishes and reaction dishes are both located on a rotation path of the first sampler, and the first sampler is used to absorb samples from the sample dishes and discharge them into the reaction dishes;

[0008] a dilution module comprising a dilution tray for storing a diluent, a rotating second sampler, and a rotatable mixing tray, wherein the mixing tray is provided with a plurality of mixing dishes, the dilution tray and the mixing dishes being located in the rotation path of the second sampler, and the mixing dishes being located in the rotation path of the first sampler;

[0009] The reagent taking module comprises a reagent taking device and a rotatable reagent tray. The reagent tray is provided with a plurality of reagent vessels. The reagent taking device is used to absorb the reagents in the reagent vessels and discharge them into the reaction vessels.

[0010] Compared with the existing technology, the above solution integrates the sampling module, dilution module and reagent collection module around the analysis module, realizing a fully automated process of sampling, dilution, reagent addition, analysis and detection of the samples to be tested, avoiding the contamination problem caused by manual intervention. At the same time, the user can adjust whether to transfer the sample directly to the reaction dish or dilute and culture the sample before transferring it to the reaction dish through the preset program, effectively improving the culture and detection efficiency of the whole machine and having good practicality.

[0011] Preferably, the upper end surface of the reaction disk is provided with a plurality of slots arranged along the circumferential direction, the reaction vessels are inserted into the slots, each of the slots is provided with an elastic clip for abutting against the reaction vessel, and the side wall of each slot is provided with an observation hole penetrating to the outer wall of the reaction disk, and the detection component is arranged toward the observation hole, so that on the one hand, the detection component can more accurately detect the sample in the reaction vessel through the observation hole, reducing light loss, and on the other hand, when necessary, the reaction vessel can be pulled out of the slot to achieve separation, which is convenient for replacement.

[0012] Preferably, the upper end surface of the reaction disk is provided with a plurality of through grooves arranged along the circumferential direction, the through grooves are arranged radially and correspond to the slots one by one, the through grooves pass through the groove walls of the slots and the outer side walls of the reaction disk, and the elastic clips are arranged radially along the reaction disk. The arrangement of the through grooves enables the reaction disk to be elastically deformed appropriately along the circumferential direction, and the elastic clips realize elastic abutment against the reaction dish in the radial direction, thereby ensuring that the connection between the reaction dish and the reaction disk is more stable and more convenient to assemble and disassemble.

[0013] Preferably, the analysis module also includes a support frame, which is provided with a receiving groove, the reaction disk is annular and is rotatably connected to the inside of the receiving groove, the side wall of the receiving groove is detachably connected to a mounting seat, and the detection component is connected to the mounting seat. After adopting this structure, the receiving groove can form a relatively stable culture environment for the reaction disk, and the setting of the mounting seat facilitates the installation and adjustment of the detection component.

[0014] Preferably, the mounting base includes a first base and a second base arranged along the circumference of the accommodating groove, and the detection module includes two scattered light detectors and one transmissive light detector, the two scattered light detectors are respectively connected to the upper and lower parts of the first base, and the first base is provided with a light path on the side facing the observation hole, and the light path is connected to the two scattered light detectors; the transmissive light detector is connected to the second base and is arranged toward the observation hole.

[0015] Preferably, the dilution plate is provided with a plurality of detachable dilution dishes, and the dilution dishes are arranged along the direction of the rotation path of the second sampler, so as to facilitate the second sampler to add the diluent into the mixing dish to achieve dilution and mixing.

[0016] Preferably, the dilution module further comprises an assembly tray, which is detachably connected to the mixing tray, the mixing dish is fan-shaped, and the upper end surface of each mixing dish is provided with a plurality of liquid storage tubes, the assembly tray is provided with a plurality of female plug-ins arranged along the circumferential direction, and the mixing dish is provided with a sub-plug-in for fitting into the female plug-in, so that a single mixing dish can be taken out directly, and all mixing dishes can be taken out at once directly through the assembly tray, which is simple and convenient to operate and has good practicality.

[0017] Preferably, the device further includes a cleaning module arranged toward the reaction dish and a power source for driving the cleaning module to rise and fall. The cleaning module includes a plurality of cleaning components, a plurality of water washing components, and a suction component arranged in sequence. The cleaning component includes a first nozzle for spraying cleaning liquid toward the reaction dish and a first suction pipe for absorbing liquid from the reaction dish. The water washing component includes a second nozzle for spraying water toward the reaction dish and a second suction pipe for absorbing liquid from the reaction dish. The suction component is used to suck the interior of the reaction dish, thereby not only achieving effective cleaning of the reaction dish but also improving cleaning efficiency.

[0018] Preferably, the suction assembly includes a third suction pipe, the lower part of the third suction pipe is provided with a guide block for extending into the interior of the reaction vessel, the lower end of the guide block is provided with an air hole connected to the third suction pipe, and a gap is left between the side of the guide block and the side wall of the reaction vessel to form an air duct, thereby ensuring that the suction assembly can completely suck out the residual liquid in the reaction vessel.

[0019] Preferably, the bottom of the guide block is provided with a plurality of downwardly protruding guide cone angles, the upper ends of the guide cone angles are arranged toward the air holes, and the lower ends of the guide cone angles are used to abut against the top corners of the bottom of the reaction dish, so that when the third suction pipe is suctioning, the residual liquid in the reaction dish can enter the air holes along the guide cone angles, further improving the suction effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 Axonometric diagram of the fully automated protein analysis system after removing the outer shell;

[0021] Figure 2 This is a top view of the fully automated protein analysis system after removing the outer shell;

[0022] Figure 3 for Figure 2 A partial enlarged schematic diagram of area A in the middle;

[0023] Figure 4 for Figure 1 A partial enlarged schematic diagram of area B in the middle;

[0024] Figure 5 for Figure 1 A partial enlarged schematic diagram of the area B after the support frame is removed;

[0025] Figure 6 for Figure 1 A partial enlarged schematic diagram of the middle C area;

[0026] Figure 7 for Figure 1 A partially enlarged schematic diagram of another embodiment of the middle C region;

[0027] Figure 8 for Figure 2 A partial enlarged schematic diagram of the D area in the middle.

[0028] Description of reference numerals:

[0029] a1-reaction tray; a11-reaction dish; a12-slot; a13-observation hole; a14-through slot; a2-support frame; a21-accommodation slot; a31-first base; a32-second base; a4-elastic buckle;

[0030] b1-sample tray; b11-sample dish; b2-first sampler;

[0031] c1-mixing plate; c11-mixing dish; c12-liquid storage tube; c13-daughter plug-in; c2-assembly plate; c21-mother plug-in; c3-dilution plate; c31-dilution dish; c4-second sampler;

[0032] d1-reagent tray; d11-reagent dish; d2-reagent dispenser;

[0033] e1-power source; e2-cleaning component; e21-first nozzle; e22-first suction pipe; e3-water washing component; e31-second nozzle; e32-second suction pipe; e4-suction component; e41-third suction pipe; e42-guide block; e43-guide cone angle. DETAILED DESCRIPTION

[0034] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail in conjunction with the accompanying drawings. The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention. It should also be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back, inside, and outside) are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0035] See also Figures 1-6 , an embodiment of the present invention provides a fully automatic protein analysis system, comprising:

[0036] The analysis module includes a detection assembly and a rotatable reaction disk a1. The reaction disk a1 is provided with a plurality of reaction vessels a11 distributed along the circumference. The detection assembly includes at least one of a transmission light detector and a scattered light detector. The detection assembly is positioned directly opposite the reaction vessels a11.

[0037] The sampling module includes a rotating first sampler b2 and a rotatable sample tray b1. The sample tray b1 is provided with several sample dishes b11. Both the sample dishes b11 and the reaction dishes a11 are located in the rotation path of the first sampler b2. The first sampler b2 is used to aspirate samples from the sample dishes b11 and discharge them into the reaction dishes a11.

[0038] The dilution module includes a dilution tray c3 for storing diluent, a rotating second sampler c4, and a rotatable mixing tray c1. The mixing tray c1 is provided with a plurality of mixing dishes c11. The dilution tray c3 and the mixing dishes c11 are located in the rotation path of the second sampler c4. The mixing dishes c11 are located in the rotation path of the first sampler b2.

[0039] The reagent dispensing module includes a reagent dispensing device d2 and a rotatable reagent disk d1. The reagent disk d1 is provided with a plurality of reagent dishes d11. The reagent dispensing device d2 is used to absorb the reagents in the reagent dishes d11 and discharge them into the reaction dish a11.

[0040] The first sampler b2, the second sampler c4 and the reagent extractor d2 in the above scheme are preferably liftable sampling needles, and are driven to rotate by a motor, so that the operation is simple and the operation is reliable; compared with the existing technology, the above scheme integrates the sampling module, dilution module and reagent extractor module around the analysis module, thereby realizing a fully automated process of sampling, dilution, reagent addition, analysis and detection of the samples to be tested, avoiding the contamination problem caused by manual intervention, and at the same time, the user can adjust whether to transfer the sample directly to the reaction dish a11 or to dilute and culture the sample before transferring it to the reaction dish a11 through a preset program, effectively improving the culture and detection efficiency of the whole machine and having good practicality.

[0041] In this embodiment, the upper end surface of the reaction disk a1 is provided with a plurality of slots a12 arranged along the circumferential direction, and the reaction dish a11 is inserted into the slots a12. Each slot a12 is provided with an elastic clip a4 for abutting against the reaction dish a11, and the side wall of each slot a12 is provided with an observation hole a13 that penetrates to the outer wall of the reaction disk a1. The detection component is arranged toward the observation hole a13, so that on the one hand, the detection component can more accurately detect the sample in the reaction dish a11 through the observation hole a13, reducing light loss. On the other hand, when necessary, the reaction dish a11 can be pulled out of the slot a12 to achieve separation, which is convenient for replacement.

[0042] Furthermore, the upper end surface of the reaction disk a1 is provided with a plurality of circumferentially arranged through slots a14. The through slots a14 are radially arranged and correspond to the slots a12 one by one. The through slots a14 extend between the groove wall of the slots a12 and the outer wall of the reaction disk a1. One side of the elastic clip a4 is connected to the slot a12, and the other side is arc-shaped and arranged radially along the reaction disk a1, thereby achieving elastic abutment against the reaction vessels a11 in the radial direction. The provision of the through slots a14 allows the reaction disk a1 to appropriately elastically deform circumferentially, thereby ensuring a more stable connection between the reaction vessels a11 and the reaction disk a1 and more convenient assembly and disassembly.

[0043] Furthermore, the groove wall of each slot a12 is provided with two radially arranged embedding grooves, and the two embedding grooves are respectively located on both sides of the through groove a14 corresponding to the same slot a12. Each embedding groove corresponds to an elastic clip a4, and one side of the elastic clip a4 is engaged in the embedding groove and the other side is in contact with the reaction dish a11, thereby achieving a better fixing effect on the reaction dish a11.

[0044] As an extension of this embodiment, the analysis module also includes a support frame a2, which is provided with an annular receiving groove a21. The reaction disk a1 is annular and rotatably connected to the interior of the receiving groove a21. A mounting base is removably connected to the outer wall of the receiving groove a21, and the detection assembly is connected to the mounting base. With this structure, the receiving groove a21 creates a relatively stable incubation environment for the reaction disk a1, and the installation of the mounting base facilitates the installation and adjustment of the detection assembly. In this embodiment, the mounting base includes a first base a31 and a second base a32 arranged along the circumference of the accommodating groove a21, and the detection module includes two scattered light detectors and a transmissive light detector. The two scattered light detectors are respectively connected to the upper and lower parts of the first base a31. A light path is provided on the side of the first base a31 facing the observation hole a13, and the light path is connected to the two scattered light detectors, so that the accuracy of subsequent detection and analysis is effectively improved by taking the average of the parameters detected by the two scattered light detectors; the transmissive light detector is connected to the second base a32 and is arranged toward the observation hole a13, so as to realize accurate detection of the transmitted light of the reaction dish a11.

[0045] In addition, the support frame a2 is also provided with a temperature adjustment component and a humidity adjustment component (not shown in the figure). The temperature adjustment component is used to adjust the temperature inside the receiving tank a21, and the humidity adjustment component is used to adjust the humidity inside the receiving tank a21, so that the reaction dish a11 can perform a culture reaction in a specific environment.

[0046] like Figure 8 As shown, in this embodiment, the dilution plate c3 is provided with a plurality of detachable dilution dishes c31, and the dilution dishes c31 are arranged along the direction of the rotation path of the second sampler c4, so that the second sampler c4 can add the diluent to the mixing dish c11 to achieve dilution and mixing.

[0047] Furthermore, the dilution module further comprises an assembly tray c2, which is detachably placed above the mixing tray c1. The mixing dish c11 is fan-shaped, and the upper end surface of each mixing dish c11 is provided with a plurality of liquid storage tubes c12. The assembly tray c2 is provided with a plurality of female plug-ins c21 arranged along the circumferential direction, and the mixing dish c11 is provided with a sub-plug-in c13 for matching to the female plug-in c21, so that a single mixing dish c11 can be directly taken out, and all mixing dishes c11 can be directly taken out at once through the assembly tray c2, which is simple and convenient to operate and has good practicality. In the present embodiment, the female plug-in c21 is a raised column, and the sub-plug-in c13 is a through hole, so that the detachable connection between the mixing dish c11 and the assembly tray c2 can be achieved by plugging, and the connection is reliable and easy to operate. Of course, the female plug-in c21 and the sub-plug-in c13 can also be replaced with other common connection methods, such as buckle connection or clamping, which is not limited by the present design. The middle part of the assembly tray c2 is also provided with a handle for holding, so as to further facilitate user operation.

[0048] As an extension of this embodiment, it also includes a cleaning module positioned toward the reaction vessel a11 and a power source e1 for driving the cleaning module up and down. The power source e1 is preferably a vertically arranged ball screw motor pair, which allows for smoother and more accurate operation. The cleaning module includes a plurality of cleaning components e2, a plurality of water washing components e3, and a suction component e4, which are arranged in sequence. The cleaning component e2 includes a first nozzle e21 for spraying cleaning liquid onto the reaction vessel a11 and a first suction pipe e22 for absorbing liquid from the reaction vessel a11. The water washing component e3 includes a second nozzle e31 for spraying water onto the reaction vessel a11 and a second suction pipe e32 for absorbing liquid from the reaction vessel a11. The suction component e4 is used to suck liquid from the reaction vessel a11, thereby effectively cleaning the reaction vessel a11 and improving cleaning efficiency. In addition, the number of cleaning components e2, water washing components e3, and suction components e4 can be set as needed. In this embodiment, there are four cleaning components e2 and two water washing components e3.

[0049] Furthermore, the suction component e4 includes a third suction pipe e41, and the lower part of the third suction pipe e41 is provided with a guide block e42 for extending into the interior of the reaction vessel a11. The lower end of the guide block e42 is provided with an air hole connected to the third suction pipe e41. The cross-sectional shape of the guide block e42 is similar to the cross-sectional shape of the reaction vessel a11, but the cross-sectional size of the guide block e42 is smaller than the cross-sectional size of the reaction vessel a11, so that a gap is left between the outer side surface of the guide block e42 and the inner wall of the reaction vessel a11 to form an air duct, ensuring that the suction component e4 can completely suck out the residual liquid in the reaction vessel a11.

[0050] like Figure 7 As shown, in another embodiment, the bottom of the guide block e42 is provided with a plurality of downwardly protruding guide cones e43. The upper ends of the guide cones e43 are positioned toward the air holes, and the lower ends of the guide cones e43 are configured to abut against the top corners of the bottom of the reaction vessel a11. For example, in this embodiment, the cross-section of the reaction vessel a11 is square, and the bottom of the reaction vessel a11 has four top corners. Therefore, there are preferably four guide cones e43, and the four guide cones e43 abut against each of the four top corners of the reaction vessel a11. Thus, when the third suction tube e41 is suctioning, the residual liquid in the reaction vessel a11 can flow along the guide cones e43 into the air holes, further improving the suction effect.

[0051] In other embodiments, the cleaning module also includes a connecting frame, and the cleaning component e2, the water washing component e3 and the suction component e4 are all slidably connected to the connecting frame. The connecting frame is provided with a spring for pushing the cleaning component e2, the water washing component e3 and the suction component e4 toward the reaction dish a11, so that the cleaning component e2, the water washing component e3 and the suction component e4 can form a certain sliding buffer margin relative to the reaction dish a11 to reduce the probability of damage. At the same time, it also enables the cleaning component e2, the water washing component e3 and the suction component e4 to penetrate deeper into the reaction dish a11, thereby achieving a better cleaning effect on the bottom of the reaction dish a11. It should be noted that the specific arrangement of the springs can be designed as needed. For example, there can be multiple springs, with at least one spring corresponding to each cleaning assembly e2, water-washing assembly e3, and suction assembly e4. Taking cleaning assembly e2 as an example, the upper end of the spring corresponding to cleaning assembly e2 is connected to the connecting frame, and the lower end of the spring corresponding to cleaning assembly e2 is connected to the middle of the first suction pipe e22 and the first nozzle e21. Therefore, when the lower ends of the first suction pipe e22 and the first nozzle e21 are inserted deeply into the reaction vessel a11 and contact the bottom of the reaction vessel a11, the cleaning assembly e2 will be able to slide upward relative to the connecting frame. After the deep cleaning is completed, the spring corresponding to cleaning assembly e2 drives the cleaning assembly e2 to return to its original position relative to the connecting frame. The arrangement of the springs corresponding to the water-washing assembly e3 and the suction assembly e4 is similar and will not be further described here.

[0052] Although the present disclosure is disclosed as above, the protection scope of the present disclosure is not limited thereto. For those skilled in the art, various changes and modifications can be made without departing from the spirit and scope of the present disclosure, and these changes and modifications will fall within the protection scope of the present invention.

Claims

1. A fully automatic protein analysis system, characterized in that: have: The analysis module comprises a detection component and a rotatable reaction disk (a1), wherein the reaction disk (a1) is provided with a plurality of reaction vessels (a11) distributed along the circumference, the detection component comprises at least one of a transmission light detector and a scattering light detector, and the detection component is arranged facing the reaction vessels (a11); The sampling module comprises a rotating first sampler (b2) and a rotatable sample tray (b1), wherein the sample tray (b1) is provided with a plurality of sample dishes (b11), and the sample dishes (b11) and the reaction dishes (a11) are both located on the rotating path of the first sampler (b2); A dilution module, comprising a dilution plate (c3) for storing a diluent, a rotating second sampler (c4) and a rotatable mixing plate (c1), wherein the mixing plate (c1) is provided with a plurality of mixing dishes (c11), the dilution plate (c3) and the mixing dishes (c11) are located on a rotating path of the second sampler (c4), and the mixing dishes (c11) are located on a rotating path of the first sampler (c2); A reagent taking module, comprising a reagent taking device (d2) and a rotatable reagent disk (d1), wherein the reagent disk (d1) is provided with a plurality of reagent vessels (d11), and the reagent taking device (d2) is used to absorb the reagent in the reagent vessel (d11) and discharge it into the reaction vessel (a11); It also includes a cleaning module arranged toward the reaction dish (a11) and a power source (e1) for driving the cleaning module to rise and fall, the cleaning module includes a plurality of cleaning components (e2), a plurality of water washing components (e3), and a suction component (e4) arranged in sequence, the cleaning component (e2) includes a first spray pipe (e21) for spraying cleaning liquid toward the reaction dish (a11) and a first suction pipe (e22) for absorbing liquid from the reaction dish (a11), the water washing component (e3) includes a second spray pipe (e31) for spraying water toward the reaction dish (a11) and a second suction pipe (e32) for absorbing liquid from the reaction dish (a11), and the suction component (e4) is used to suck the interior of the reaction dish (a11); The suction assembly (e4) comprises a third suction pipe (e41), a guide block (e42) for extending into the reaction vessel (a11) is provided at the lower part of the third suction pipe (e41), a wind hole connected to the third suction pipe (e41) is provided at the lower end of the guide block (e42), and a gap is left between the side of the guide block (e42) and the side wall of the reaction vessel (a11) to form an air duct; The bottom of the guide block (e42) is provided with a plurality of guide cone angles (e43) protruding downwards, the upper ends of the guide cone angles (e43) are arranged toward the air holes, and the lower ends of the guide cone angles (e43) are used to abut against the top corners of the bottom of the reaction vessel (a11).

2. The fully automatic protein analysis system according to claim 1, characterized in that: The upper end surface of the reaction disk (a1) is provided with a plurality of slots (a12) arranged along the circumferential direction, the reaction vessels (a11) are inserted into the slots (a12), each of the slots (a12) is provided with an elastic buckle (a4) for abutting against the reaction vessel (a11), the side wall of each of the slots (a12) is provided with an observation hole (a13) penetrating to the outer wall of the reaction disk (a1), and the detection component is arranged toward the observation hole (a13).

3. The fully automatic protein analysis system according to claim 2, characterized in that: The upper end surface of the reaction disk (a1) is provided with a plurality of through grooves (a14) arranged along the circumferential direction, the through grooves (a14) are arranged along the radial direction and correspond to the slots (a12) one by one, the through grooves (a14) pass through between the groove wall of the slot (a12) and the outer side wall of the reaction disk (a1), and the elastic buckle (a4) is arranged along the radial direction of the reaction disk (a1).

4. The fully automatic protein analysis system according to claim 2 or 3, characterized in that: The analysis module also includes a support frame (a2), a receiving groove (a21) is provided on the support frame (a2), the reaction disk (a1) is annular and is rotatably connected to the inside of the receiving groove (a21), the side wall of the receiving groove (a21) is detachably connected to a mounting seat, and the detection component is connected to the mounting seat.

5. The fully automatic protein analysis system according to claim 4, characterized in that: The mounting base comprises a first base (a31) and a second base (a32) arranged along the circumference of the accommodating groove (a21); the detection module comprises two scattered light detectors and one transmissive light detector; the two scattered light detectors are respectively connected to the upper and lower parts of the first base (a31); a light path is provided on one side of the first base (a31) facing the observation hole (a13), and the light path is connected to the two scattered light detectors; the transmissive light detector is connected to the second base (a32) and is arranged toward the observation hole (a13).

6. The fully automatic protein analysis system according to claim 1, characterized in that: The dilution plate (c3) is provided with a plurality of detachable dilution dishes (c31), and the dilution dishes (c31) are arranged along the direction of the rotation path of the second sampler (c4).

7. The fully automatic protein analysis system according to claim 1 or 6, characterized in that: The dilution module also includes an assembly plate (c2), the assembly plate (c2) and the mixing plate (c1) are detachably connected, the mixing dish (c11) is fan-shaped, and the upper end surface of each mixing dish (c11) is provided with a plurality of liquid storage tubes (c12), the assembly plate (c2) is provided with a plurality of female plug-ins (c21) arranged along the circumferential direction, and the mixing dish (c11) is provided with a sub-plug-in (c13) for matching with the female plug-in (c21).

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