Radiotherapy guidance device, method, electronic device and storage medium

Abstract

The present invention provides a radiotherapy guidance device, method, electronic device and storage medium, wherein the device includes: an image data acquisition module for acquiring historical radiotherapy image data of an object to be treated, the historical radiotherapy image data including multiple radiotherapy sub-image data; a physiological motion phase acquisition module for acquiring real-time physiological motion information of the object to be treated and determining multiple real-time physiological motion phases of the real-time physiological motion information; an image data determination module for determining the historical physiological motion phase corresponding to the real-time physiological motion, and determining the radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase; and a radiotherapy guidance module for guiding the radiotherapy process based on the radiotherapy sub-image data. The present invention can guide the radiotherapy process by obtaining the real-time physiological motion phase, thereby improving the efficiency and accuracy of the radiotherapy guidance; and there is no need to set up additional structures such as a mechanical arm, thereby reducing the cost of the radiotherapy guidance method.

Description

Technical Field

[0001] The present invention relates to the technical field of radiotherapy, and in particular to a radiotherapy guiding device, method, electronic equipment and storage medium. Background Art

[0002] Radiotherapy is one of the main technical means of treating malignant tumors. Its goal is to irradiate the affected part (tumor) with radiation as much as possible. In radiotherapy, which irradiates the affected part with radiation such as X-rays and electron beams, it is necessary to accurately irradiate the affected part. However, sometimes the affected part moves with the patient's physiological movements (such as breathing, heartbeat, pulse, etc.). For example, a tumor near the lung moves greatly due to breathing.

[0003] In order to achieve accurate radiotherapy during the radiotherapy process, a pair of independent robotic arms are provided in the prior art to perform real-time imaging observation on the patient during the radiotherapy process so as to determine the affected part during the radiotherapy process.

[0004] The existing technology has the following problems: the setting cost of the robotic arm is high and the structure is complex, and the operator needs to manually control the movement of the robotic arm as the radiotherapy process proceeds, which is complicated to operate and results in low efficiency and accuracy of radiotherapy guidance. Summary of the invention

[0005] In view of this, it is necessary to provide a radiotherapy guidance device, method, electronic device and storage medium to solve the technical problems existing in the prior art of high cost of radiotherapy guidance and low efficiency and accuracy of radiotherapy guidance.

[0006] In one aspect, the present invention provides a radiation therapy guiding device,

[0007] It includes an image data acquisition module, a physiological motion phase acquisition module, an image data determination module and a radiotherapy guidance module;

[0008] The image data acquisition module is used to acquire historical radiotherapy image data of the subject to be treated, wherein the historical radiotherapy image data includes a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements;

[0009] The physiological motion phase acquisition module is used to acquire the real-time physiological motion information of the subject to be treated, and determine a plurality of real-time physiological motion phases of the real-time physiological motion information;

[0010] The image data determination module is used to determine the historical physiological motion phase corresponding to the real-time physiological motion, and determine the radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase;

[0011] The radiotherapy guiding module is used to guide the radiotherapy process based on the radiotherapy sub-image data.

[0012] In some possible implementations, the radiotherapy guidance module is specifically used to:

[0013] Determine whether the radiotherapy process needs to be adjusted based on the radiotherapy sub-image data.

[0014] In some possible implementations, the radiotherapy guidance module includes a treatment field acquisition submodule, a region of interest acquisition submodule, and an adjustment judgment submodule;

[0015] The treatment field acquisition submodule is used to acquire the treatment field in the radiotherapy plan;

[0016] The region of interest acquisition submodule is used to determine the corrected region of interest in the radiotherapy sub-image data;

[0017] The adjustment judgment submodule is used to determine whether the radiotherapy process needs to be adjusted according to the treatment field and the correction region of interest.

[0018] In some possible implementations, the adjustment judgment submodule includes an overlapping area acquisition unit and an adjustment judgment unit;

[0019] The overlapping area acquisition unit is used to acquire the overlapping area of ​​the overlapping part of the treatment field and the correction region of interest;

[0020] The adjustment judgment unit is used to judge whether the radiotherapy process needs to be adjusted according to the overlapping area.

[0021] In some possible implementations, the adjustment determination unit includes an area ratio determination subunit and a first adjustment subunit;

[0022] The area ratio judgment subunit is used to judge whether the ratio of the overlap area to the area of ​​the corrected region of interest of the corrected region of interest is greater than or equal to a first threshold;

[0023] The first adjustment subunit is used to adjust the radiotherapy process when the ratio of the overlap area to the corrected ROI area is less than the first threshold.

[0024] In some possible implementations, the region of interest acquisition submodule includes an original region acquisition unit, a registration relationship acquisition unit, and a region correction unit;

[0025] The original region acquisition unit is used to acquire the original region of interest of the planned image in the radiotherapy plan;

[0026] The registration relationship acquisition unit is used to acquire the registration relationship between the original region of interest and the corrected region of interest;

[0027] The region correction unit is used to determine the corrected region of interest based on the registration relationship and the original region of interest.

[0028] In some possible implementations, the radiation therapy guidance device further includes:

[0029] A dynamic display module is used to dynamically display the radiotherapy sub-image data corresponding to each real-time physiological movement according to the multiple real-time physiological movement phases.

[0030] In another aspect, the present invention further provides a radiotherapy guidance method, comprising:

[0031] Acquiring historical radiotherapy image data of the subject to be treated, wherein the historical radiotherapy image data includes a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements;

[0032] Acquiring real-time physiological motion information of the subject to be treated, and determining a plurality of real-time physiological motion phases of the real-time physiological motion information;

[0033] Determine the historical physiological motion phase corresponding to the real-time physiological motion, and determine the radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase;

[0034] The radiotherapy process is guided based on the radiotherapy sub-image data.

[0035] On the other hand, the present invention also provides an electronic device, including a memory and a processor, wherein:

[0036] The memory is used to store programs;

[0037] The processor is coupled to the memory and is used to execute the program stored in the memory to implement the steps in the radiotherapy guidance method described in any of the above implementations.

[0038] On the other hand, the present invention also provides a computer-readable storage medium for storing a computer-readable program or instruction, which, when executed by a processor, can implement the steps in the radiotherapy guidance method described in any of the above implementations.

[0039] The beneficial effects of adopting the above-mentioned embodiments are as follows: the radiotherapy guidance device provided by the present invention acquires historical radiotherapy image data by setting an image data acquisition module, and the historical radiotherapy image data includes multiple radiotherapy sub-image data corresponding to multiple historical physiological movements; then acquires real-time physiological motion information by means of a physiological motion phase acquisition module, and determines multiple real-time physiological motion phases of the real-time physiological motion information; then determines the radiotherapy sub-image data corresponding to the real-time physiological movement by means of an image data determination module, and the radiotherapy guidance module guides the radiotherapy process based on the radiotherapy sub-image data. The present invention does not need to image the affected part while acquiring the real-time physiological motion information, and can determine the corresponding radiotherapy sub-image data by obtaining the real-time physiological motion phase, and guide the radiotherapy process, thereby improving the efficiency and accuracy of the radiotherapy guidance; and, the corresponding radiotherapy sub-image data can be obtained only by means of the real-time physiological motion phase, and there is no need to set up additional structures such as a mechanical arm, thereby reducing the cost of the radiotherapy guidance device for radiotherapy guidance. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative work.

[0041] Figure 1 A schematic structural diagram of an embodiment of a radiotherapy guidance device provided by the present invention;

[0042] Figure 2 A schematic diagram of an embodiment of real-time breathing information provided by the present invention;

[0043] Figure 3 A schematic diagram of the structure of an embodiment of a radiotherapy guidance module provided by the present invention;

[0044] Figure 4 A schematic diagram of the structure of an embodiment of the adjustment judgment submodule provided by the present invention;

[0045] Figure 5 A schematic diagram of a flow chart of an embodiment of an adjustment judgment unit provided by the present invention;

[0046] Figure 6 A schematic flow chart of another embodiment of the adjustment judgment unit provided by the present invention;

[0047] Figure 7 A schematic diagram of an embodiment of a flow chart of a region of interest acquisition submodule provided by the present invention;

[0048] Figure 8A schematic structural diagram of another embodiment of the radiotherapy guidance device provided by the present invention;

[0049] Fig. 9 A schematic flow chart of an embodiment of the radiotherapy guidance method provided by the present invention;

[0050] Fig.10 A schematic structural diagram of an embodiment of an electronic device provided by the present invention. DETAILED DESCRIPTION

[0051] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present invention.

[0052] In the description of the embodiments of the present invention, unless otherwise specified, "multiple" means two or more than two. "And / or" describes the association relationship of associated objects, indicating that three relationships may exist. For example, "A and / or B" may mean: A exists alone, A and B exist at the same time, and B exists alone.

[0053] In the embodiments of the present invention, the terms "radiation therapy", "radiotherapy" and "treatment" are used interchangeably to refer to treating a patient. The terms "subject to be treated", "patient", "treatment area", and "tumor" are used interchangeably to refer to the object and / or area of ​​treatment. The terms "area", "position" and "treatment area" are used interchangeably to refer to the position of the treatment area shown in the image or the actual position of the treatment area in or on the patient's body.

[0054] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present invention. The appearance of the phrase in various places in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0055] The present invention provides a radiotherapy guiding device, method, electronic device and storage medium, which are respectively described below.

[0056] Figure 1 A schematic diagram of the structure of an embodiment of a radiotherapy guiding device provided by the present invention is shown in FIG. Figure 1As shown, the radiotherapy guiding device 10 includes an image data acquisition module 100, a physiological motion phase acquisition module 200, an image data determination module 300 and a radiotherapy guiding module 400;

[0057] The image data acquisition module 100 is used to acquire historical radiotherapy image data of the subject to be treated, wherein the historical radiotherapy image data includes a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements;

[0058] The physiological motion phase acquisition module 200 is used to acquire the real-time physiological motion information of the subject to be treated, and determine a plurality of real-time physiological motion phases of the real-time physiological motion information;

[0059] The image data determination module 300 is used to determine the historical physiological motion phase corresponding to the real-time physiological motion, and determine the radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase;

[0060] The radiotherapy guidance module 400 is used to guide the radiotherapy process based on the radiotherapy sub-image data.

[0061] It should be understood that the historical radiotherapy image data in the image data acquisition module 100 is acquired before the radiotherapy, and the real-time physiological motion information in the physiological motion phase acquisition module 200 is acquired during the radiotherapy.

[0062] Compared with the prior art, the radiotherapy guidance device 10 provided in the embodiment of the present invention obtains historical radiotherapy image data before radiotherapy through the image data acquisition module 100, and the historical radiotherapy image data includes multiple radiotherapy sub-image data corresponding to multiple historical physiological movements; obtains real-time physiological movement information during radiotherapy through the physiological movement phase acquisition module 200, and determines multiple real-time physiological movement phases of the real-time physiological movement information; then determines the radiotherapy sub-image data corresponding to the real-time physiological movement through the image data determination module 300, and the radiotherapy guidance module 400 guides the radiotherapy process based on the radiotherapy sub-image data. In the embodiment of the present invention, there is no need to image the affected part during radiotherapy. By obtaining the real-time physiological movement phase, the corresponding radiotherapy sub-image data can be determined to guide the radiotherapy process, thereby improving the efficiency and accuracy of radiotherapy guidance; and, the corresponding radiotherapy sub-image data can be obtained only through the real-time physiological movement phase, without the need to set up additional structures such as a mechanical arm, thereby reducing the cost of the radiotherapy guidance device.

[0063] It should be noted that the historical radiotherapy image data can be any one of four-dimensional image data, three-dimensional image data or two-dimensional image data, and the radiotherapy sub-image data corresponds to three-dimensional image data, two-dimensional image data or one-dimensional image data. That is, compared with the radiotherapy sub-image data, the historical radiotherapy image data includes time information.

[0064] In some embodiments of the present invention, the acquisition of historical radiotherapy image data in the image data acquisition module 100 may specifically be: acquiring historical radiotherapy image data through an imaging device or an imaging device coupled with a treatment device. Specifically, the imaging device may include a single-modality scanning device or a multi-modality scanning device. The single-modality scanning device may include, for example, a positron emission tomography (PET) device, a single-photon emission computed tomography (SPECT) device, an ultrasonic device, an X-ray device, a computed tomography (CT) device, a magnetic resonance imaging (MRI) device, or the like or any combination thereof. The multi-modality scanning device may include a positron emission tomography-computed tomography (PET-CT) scanning device, a positron emission tomography-magnetic resonance imaging (PET-MRI) scanning device, or the like.

[0065] Specifically, the treatment device may be a medical accelerator, and the medical accelerator may be any medical accelerator in the prior art, such as a medical electron linear accelerator, which will not be described in detail here.

[0066] Furthermore, the image data acquisition module 100 is specifically used to: synchronously acquire historical radiotherapy image data and historical physiological motion information before radiotherapy, and determine multiple historical physiological motion phases of the historical physiological motion information, and divide the historical radiotherapy image data into multiple radiotherapy sub-image data corresponding to the multiple historical physiological motion phases based on the multiple historical physiological motion phases.

[0067] In some embodiments of the present invention, the historical physiological motion information and the real-time physiological motion information are presented in the form of a historical physiological motion waveform curve and a real-time physiological motion waveform curve, respectively.

[0068] In some embodiments of the present invention, the physiological motion phase may include but is not limited to a breathing phase, a pulse phase, and a heartbeat phase.

[0069] In a specific embodiment of the present invention, the physiological motion phase is a respiratory phase; the historical physiological motion phase in the image data acquisition module 100 and the real-time victory motion phase in the physiological motion phase acquisition module 200 are both respiratory phases, wherein the respiratory phase may include an inspiratory phase and / or an expiratory phase. Taking the real-time respiratory waveform curve as an example, Figure 2 As shown, Figure 2 The horizontal axis is time, and the vertical axis is breathing amplitude, then Figure 2The curve in is the real-time breathing waveform curve. In some embodiments of the present invention, the trough in the real-time breathing waveform curve may correspond to the end of the exhalation phase, and the peak may correspond to the end of the inspiration phase. Then, along the time sequence, from a trough to the adjacent peak is the inspiration phase, and from a peak to the adjacent trough is the exhalation phase.

[0070] It should be understood that: in some embodiments, one inspiratory phase or one expiratory phase may correspond to one radiotherapy sub-image data. In other embodiments, one radiotherapy sub-image data may include at least two inspiratory phases or at least two expiratory phases. Specifically, how many inspiratory phases or respiratory phases one radiotherapy sub-image data includes may be adjusted according to actual conditions, which will not be elaborated here.

[0071] In some embodiments of the present invention, the object to be treated in the image data acquisition module 100 and the object to be treated in the physiological motion phase acquisition module 200 can be biological or non-biological. For example, the object to be treated can be a human body, an animal body, an artificial object (e.g., a phantom), etc. Specifically, the object to be treated can include a specific part of the body, such as the head, chest, abdomen, etc. or any combination thereof. In addition, the object to be treated can also include a specific organ, such as the heart, esophagus, trachea, bronchus, stomach, gallbladder, small intestine, colon, bladder, ureter, uterus, fallopian tube, etc.

[0072] In some embodiments of the present invention, obtaining historical radiotherapy image data before radiotherapy may refer to a shorter time before radiotherapy (e.g., 1 minute, 3 minutes, 5 minutes, etc. before radiotherapy); before radiotherapy may also refer to a longer time before radiotherapy (e.g., 1 day, 3 days, 5 days, etc.). The specific time when the radiotherapy image data is obtained can be adjusted according to actual conditions and will not be elaborated here.

[0073] In some embodiments of the present invention, the acquisition method of the real-time respiratory information in the physiological motion phase acquisition module 200 includes but is not limited to: acquiring through a contact respiratory waveform curve acquisition device or a non-contact respiratory waveform curve acquisition device.

[0074] In some embodiments of the present invention, the radiotherapy guidance module 400 is specifically used for:

[0075] Determine whether the radiation therapy process needs to be adjusted based on the radiation therapy sub-image data.

[0076] The embodiment of the present invention can protect the subject to be treated while performing radiotherapy on the subject by determining whether the radiotherapy process needs to be adjusted according to the radiotherapy sub-image data.

[0077] In some embodiments of the present invention, adjusting the radiotherapy process includes, but is not limited to: interrupting the radiotherapy process or adjusting the radiotherapy plan.

[0078] Specifically, adjusting the radiotherapy plan may be adjusting the treatment field in the radiotherapy plan.

[0079] In some embodiments of the present invention, Figure 3 As shown, the radiotherapy guidance module 400 includes a treatment field acquisition submodule 410, a region of interest acquisition submodule 420, and an adjustment judgment submodule 430;

[0080] The treatment field acquisition submodule 410 is used to acquire the treatment field in the radiotherapy plan;

[0081] The region of interest acquisition submodule 420 is used to determine the corrected region of interest in the radiotherapy sub-image data;

[0082] The adjustment determination submodule 430 is used to determine whether the radiotherapy process needs to be adjusted according to the treatment field and the correction region of interest.

[0083] By determining whether the radiotherapy process needs to be adjusted based on the treatment settings and the correction region of interest, it can be ensured that the radiation beam is irradiated into the correction region of interest, and the radiation beam is prevented from irradiating other areas except the correction region of interest, thereby affecting the normal tissues and organs of the treated subject, thereby further improving the reliability and safety of the radiotherapy device.

[0084] It should be understood that the radiotherapy plan in the treatment field acquisition submodule 410 refers to the treatment plan formulated based on the shape and position of the tumor in the patient's body before the tumor in the patient's body is treated, that is, the treatment field in the radiotherapy equipment, the dose rate received by each position of the tumor, the position of the frame in the radiotherapy equipment, etc.

[0085] In some embodiments of the present invention, the treatment field in the treatment field acquisition submodule 410 is the irradiation range of the ray beam after passing through the conformal / collimator, and the shape of the treatment field can be any one of square, rectangular, circular or irregular shapes.

[0086] It should be noted that the corrected ROI in the ROI acquisition submodule 420 is delineated based on the isocenter, which is the center of the treatment field. The isocenter refers to the point where the rotation axes of the medical electron linear accelerator's frame, radiation head and treatment bed intersect.

[0087] It should also be noted that in some embodiments of the present invention, the radiotherapy guidance module 400 is also used for:

[0088] The radiation dose of the radiation beam within the correction region of interest in the radiotherapy sub-image data is determined, and when the radiation dose is greater than a threshold dose, the radiotherapy process is adjusted.

[0089] By determining whether to adjust the radiotherapy process based on the radiation dose, it is possible to avoid excessive radiation beams irradiating the object to be treated, causing damage to the object to be treated, and further improve the safety and reliability of the radiotherapy process.

[0090] In some embodiments of the present invention, Figure 4 As shown, the adjustment judgment submodule 430 includes an overlapping area acquisition unit 431 and an adjustment judgment unit 432;

[0091] The overlapping area acquisition unit 431 is used to acquire the overlapping area of ​​the overlapping part of the treatment field and the correction region of interest;

[0092] The adjustment determination unit 432 is used to determine whether the radiotherapy process needs to be adjusted according to the overlap area.

[0093] Specifically, in some embodiments of the present invention, Figure 5 As shown, the adjustment judgment unit 432 includes an area judgment subunit 4321 and a second adjustment subunit 4322;

[0094] The area determination subunit 4321 is used to determine whether the overlapping area is greater than or equal to the area threshold;

[0095] The second adjustment subunit 4322 is used to adjust the radiotherapy process when the overlapping area is smaller than the area threshold.

[0096] Since the treatment field is the irradiation range of the radiation beam after passing through the conformal / collimator, that is, the treatment field is the irradiation range of the radiation beam after passing through the conformal / collimator on the human body, if the overlapping area is smaller than the area threshold, part of the corrected region of interest will be missed from irradiation, and the radiation beam may irradiate normal tissues and organs other than the corrected region of interest. Therefore, when the overlapping area is smaller than the area threshold, adjusting the radiotherapy process can improve the safety and reliability of the radiotherapy process.

[0097] Furthermore, since the area threshold is generally a constant value, and since the areas of the corrected regions of interest in different cases are different, it is not accurate to judge whether the radiotherapy process needs to be adjusted by the area threshold. Therefore, in order to improve the accuracy of judging whether the radiotherapy process needs to be adjusted, in some embodiments of the present invention, Figure 6 As shown, the adjustment judgment unit 432 includes an area ratio judgment subunit 4323 and a first adjustment subunit 4324:

[0098] The area ratio determination subunit 4323 is used to determine whether the ratio of the overlapped area to the corrected region of interest area is greater than a first threshold;

[0099] The first adjustment subunit 4324 is used to adjust the radiotherapy process when the ratio of the overlap area to the corrected ROI area is less than a first threshold.

[0100] By judging whether the radiotherapy process needs to be adjusted based on the ratio of the overlapping area to the area of ​​the corrected region of interest, compared to judging whether the radiotherapy process needs to be adjusted based on the area threshold, the judgment result will not be affected by the different areas of the corrected region of interest in different cases, thereby making the judgment more reliable and accurate.

[0101] Due to differences in the positioning of the subject to be treated or changes in the organ / lesion area of ​​the subject to be treated, there may be differences between the original planned image and the radiotherapy image. Figure 7 As shown, the region of interest acquisition submodule 420 includes an original region acquisition unit 421, a registration relationship acquisition unit 422, and a region correction unit 423;

[0102] The original region acquisition unit 421 is used to acquire the original region of interest of the planned image in the radiotherapy plan;

[0103] The registration relationship acquisition unit 422 is used to acquire the registration relationship between the original region of interest and the corrected region of interest;

[0104] The region correction unit 423 is used to determine a corrected region of interest based on the registration relationship and the original region of interest.

[0105] It should be understood that the radiotherapy plan in the original region acquisition unit 421 may be a radiotherapy plan determined by expert consultation before the radiotherapy.

[0106] The registration relationship in the registration relationship acquisition unit 422 refers to the correspondence between the change of the region of interest caused by the physiological movement of the subject to be treated and the original region of interest.

[0107] Among them, the registration relationship includes rigid registration relationship and non-rigid registration relationship. Rigid registration relationship includes translation relationship and rotation transformation relationship, and non-rigid registration includes projection relationship and elastic transformation relationship.

[0108] The embodiment of the present invention obtains the corrected region of interest of the radiotherapy sub-image data by registering the original region of interest, thereby avoiding changes in the region of interest due to differences in the positioning of the object to be treated or changes in the organ / lesion area of ​​the object to be treated, and can further improve the accuracy of radiotherapy.

[0109] In order to adjust the radiotherapy process, in some embodiments of the present invention, the radiotherapy guidance module 400 in the radiotherapy guidance device 10 is further used to:

[0110] When the radiotherapy process needs to be adjusted, the radiotherapy plan is adjusted in response to the adjustment instruction.

[0111] When the radiotherapy process needs to be adjusted, the embodiment of the present invention responds to an adjustment instruction and adjusts the radiotherapy plan based on the adjustment instruction, thereby achieving controllability of the adjustment of the radiotherapy plan.

[0112] It should be noted that adjusting the radiotherapy plan includes but is not limited to adjusting the treatment field and radiation dose in the radiotherapy plan, wherein adjusting the treatment field includes but is not limited to adjusting the shape of the treatment field. Adjusting the shape of the treatment field can be achieved by adjusting relevant parameters in the radiotherapy plan, such as adjusting the position of the leaves in the conformal / collimator.

[0113] It should be understood that the adjustment instruction can be generated by the doctor when the treatment field needs to be adjusted, or it can be automatically generated when the treatment field needs to be adjusted. The specific way in which the adjustment instruction is generated can be adjusted according to actual needs and will not be elaborated here.

[0114] It should be noted that: if the adjustment instruction is generated by the doctor when the treatment field needs to be adjusted, an interactive interface needs to be provided, and the doctor generates the adjustment instruction by clicking on the interactive interface.

[0115] The embodiment of the present invention provides two different ways to generate adjustment instructions to adjust the treatment field, thereby improving the redundancy and diversity of adjusting the treatment field.

[0116] In order to facilitate the operator to intuitively see the radiotherapy sub-image data under the current real-time physiological motion phase, in some embodiments of the present invention, Figure 8 As shown, the radiation therapy guiding device 10 further includes a dynamic display module 500;

[0117] The dynamic display module 500 is used to dynamically display the radiotherapy sub-image data corresponding to each real-time physiological motion according to multiple real-time physiological motion phases.

[0118] By dynamically displaying the radiotherapy sub-image data corresponding to each real-time physiological motion according to multiple real-time physiological motion phases, the operator can intuitively see the radiotherapy sub-image data under the current real-time physiological motion phase during the radiotherapy process.

[0119] In some embodiments of the present invention, the multiple real-time physiological motion phases include a first real-time physiological motion phase and a second real-time physiological motion phase, and the multiple radiotherapy sub-image data include first radiotherapy sub-image data corresponding to the first real-time physiological motion phase and second radiotherapy sub-image data corresponding to the second real-time physiological motion phase; the dynamic display module 500 is specifically used to:

[0120] When the real-time physiological motion phase is the first real-time physiological motion phase, displaying the first radiotherapy sub-image data;

[0121] When the real-time physiological motion phase is the second real-time physiological motion phase, the second radiotherapy sub-image data is displayed.

[0122] That is, as the real-time physiological motion phase switches, the corresponding radiotherapy sub-image data is displayed, thereby realizing the dynamic display of the radiotherapy sub-image data.

[0123] In order to better implement the radiation therapy guiding device in the embodiment of the present invention, based on the radiation therapy guiding device, correspondingly, Fig. 9 As shown, an embodiment of the present invention further provides a radiotherapy guidance method, the radiotherapy guidance method comprising:

[0124] S901, acquiring historical radiotherapy image data of the subject to be treated, the historical radiotherapy image data including a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements;

[0125] S902, obtaining real-time physiological motion information of the subject to be treated, and determining a plurality of real-time physiological motion phases of the real-time physiological motion information;

[0126] S903, determining a historical physiological motion phase corresponding to the real-time physiological motion, and determining radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase;

[0127] S904: guiding the radiotherapy process based on the radiotherapy sub-image data.

[0128] The radiotherapy guidance method provided in the above embodiment can implement the technical solution described in the above radiotherapy guidance device embodiment. The specific implementation principles of the above modules or units can refer to the corresponding contents in the above radiotherapy guidance device embodiment, which will not be repeated here.

[0129] like Fig.10 As shown, the present invention also provides an electronic device 1000. The electronic device 1000 includes a processor 1001, a memory 1002 and a display 1003. Fig.10 Only some components of the electronic device 1000 are shown, but it should be understood that it is not required to implement all of the components shown, and more or fewer components may be implemented instead.

[0130] In some embodiments, the memory 1002 may be an internal storage unit of the electronic device 1000, such as a hard disk or memory of the electronic device 1000. In other embodiments, the memory 1002 may also be an external storage device of the electronic device 1000, such as a plug-in hard disk, a smart memory card (Smart Media Card, SMC), a secure digital (Secure Digital, SD) card, a flash card (Flash Card), etc. equipped on the electronic device 1000.

[0131] Furthermore, the memory 1002 may include both an internal storage unit of the electronic device 1000 and an external storage device. The memory 1002 is used to store application software installed in the electronic device 1000 and various data.

[0132] In some embodiments, the processor 1001 may be a central processing unit (CPU), a microprocessor or other data processing chip, used to run program codes or process data stored in the memory 1002, such as the radiation therapy guidance method of the present invention.

[0133] In some embodiments, the display 1003 may be an LED display, a liquid crystal display, a touch-sensitive liquid crystal display, an OLED (Organic Light-Emitting Diode) touch device, etc. The display 1003 is used to display information on the electronic device 1000 and to display a visual user interface. The components 1001-1003 of the electronic device 1000 communicate with each other via a system bus.

[0134] In one embodiment, when the processor 1001 executes the radiation therapy guidance program in the memory 1002, the following steps may be implemented:

[0135] Acquiring historical radiotherapy image data of the subject to be treated, the historical radiotherapy image data comprising a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements;

[0136] Acquiring real-time physiological motion information of the subject to be treated, and determining a plurality of real-time physiological motion phases of the real-time physiological motion information;

[0137] Determine a historical physiological motion phase corresponding to the real-time physiological motion, and determine radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase;

[0138] Guide the radiation therapy process based on the radiation therapy sub-image data.

[0139] It should be understood that: when the processor 1001 executes the radiotherapy guidance program in the memory 1002, in addition to the above functions, other functions may also be implemented, and details may refer to the description of the corresponding method embodiments above.

[0140] Furthermore, the embodiment of the present invention does not specifically limit the type of the electronic device 1000 mentioned, and the electronic device 1000 may be a portable electronic device such as a mobile phone, a tablet computer, a personal digital assistant (PDA), a wearable device, a laptop computer, etc. Exemplary embodiments of portable electronic devices include but are not limited to portable electronic devices equipped with IOS, Android, Microsoft or other operating systems. The above-mentioned portable electronic devices may also be other portable electronic devices, such as a laptop computer with a touch-sensitive surface (e.g., a touch panel). It should also be understood that in some other embodiments of the present invention, the electronic device 1000 may not be a portable electronic device, but a desktop computer with a touch-sensitive surface (e.g., a touch panel).

[0141] Accordingly, an embodiment of the present application also provides a computer-readable storage medium, which is used to store computer-readable programs or instructions. When the program or instructions are executed by a processor, the radiotherapy guidance method steps or functions provided in the above-mentioned method embodiments can be implemented.

[0142] The radiotherapy guidance device, method, electronic device and storage medium provided by the embodiments of the present invention obtain historical radiotherapy image data before radiotherapy, and the historical radiotherapy image data includes multiple radiotherapy sub-image data corresponding to multiple historical physiological movements; obtain real-time physiological movement information during radiotherapy, and determine multiple real-time physiological movement phases of the real-time physiological movement information; then determine the radiotherapy sub-image data corresponding to the real-time physiological movement, and guide the radiotherapy process based on the radiotherapy sub-image data. There is no need to image the affected part during radiotherapy. By obtaining the real-time physiological movement phase, the corresponding radiotherapy sub-image data can be determined to guide the radiotherapy process, thereby improving the efficiency and accuracy of radiation guidance. Moreover, the corresponding radiotherapy sub-image data can be obtained only through the real-time physiological movement phase, without the need to set up additional structures such as a mechanical arm, thereby reducing the cost of the radiotherapy guidance method.

[0143] Those skilled in the art will appreciate that all or part of the processes of the above-mentioned embodiments can be implemented by instructing related hardware (such as a processor, a controller, etc.) through a computer program, and the computer program can be stored in a computer-readable storage medium, wherein the computer-readable storage medium is a disk, an optical disk, a read-only storage memory, or a random access memory, etc.

[0144] The radiotherapy guidance device, method, electronic device and storage medium provided by the present invention are introduced in detail above. Specific examples are used in this article to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea; at the same time, for technical personnel in this field, according to the idea of ​​the present invention, there will be changes in the specific implementation method and application scope. In summary, the content of this specification should not be understood as a limitation on the present invention.

Claims

1. A radiation therapy guiding device, characterized in that: It includes an image data acquisition module, a physiological motion phase acquisition module, an image data determination module and a radiotherapy guidance module; The image data acquisition module is used to acquire historical radiotherapy image data of the subject to be treated, wherein the historical radiotherapy image data includes a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements; The physiological motion phase acquisition module is used to acquire the real-time physiological motion information of the subject to be treated, and determine a plurality of real-time physiological motion phases of the real-time physiological motion information; The image data determination module is used to determine the historical physiological motion phase corresponding to the real-time physiological motion, and determine the radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase; The radiotherapy guiding module is used to guide the radiotherapy process based on the radiotherapy sub-image data. Wherein, the radiotherapy guidance module comprises: A treatment field acquisition submodule, wherein the treatment field acquisition submodule is used to acquire the treatment field in the radiotherapy plan; a region of interest acquisition submodule, the region of interest acquisition submodule being used to determine a corrected region of interest in the radiotherapy sub-image data; and An adjustment judgment submodule, the adjustment judgment submodule includes an overlapping area acquisition unit and an adjustment judgment unit; the overlapping area acquisition unit is used to obtain the overlapping area of ​​the overlapping part of the treatment field and the corrected region of interest; the adjustment judgment unit includes an area ratio judgment subunit and a first adjustment subunit; the area ratio judgment subunit is used to judge whether the ratio of the overlapping area to the area of ​​the corrected region of interest is greater than or equal to a first threshold; the first adjustment subunit is used to adjust the radiotherapy process when the ratio of the overlapping area to the area of ​​the corrected region of interest is less than the first threshold.

2. The radiation therapy guiding device according to claim 1, characterized in that: The region of interest acquisition submodule includes an original region acquisition unit, a registration relationship acquisition unit and a region correction unit; The original region acquisition unit is used to acquire the original region of interest of the planned image in the radiotherapy plan; The registration relationship acquisition unit is used to acquire the registration relationship between the original region of interest and the corrected region of interest; The region correction unit is used to determine the corrected region of interest based on the registration relationship and the original region of interest.

3. The radiation therapy guiding device according to claim 1, characterized in that: The radiotherapy guiding device also includes a dynamic display module; The dynamic display module is used to dynamically display the radiotherapy sub-image data corresponding to each real-time physiological movement according to the multiple real-time physiological movement phases.

4. An electronic device, characterized in that: comprising a memory and a processor, wherein: The memory is used to store programs; The processor is coupled to the memory and is configured to execute the program stored in the memory to implement the following steps: Acquiring historical radiotherapy image data of the subject to be treated, the historical radiotherapy image data comprising a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements; Acquiring real-time physiological motion information of the subject to be treated, and determining a plurality of real-time physiological motion phases of the real-time physiological motion information; Determine a historical physiological motion phase corresponding to the real-time physiological motion, and determine radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase; Obtain treatment fields in radiotherapy plans; determining a corrected region of interest in the radiotherapy sub-image data; Acquire the overlapping area of ​​the treatment field and the overlapping portion of the correction region of interest; Determining whether the ratio of the overlapping area to the area of ​​the corrected ROI is greater than or equal to a first threshold; When the ratio of the overlap area to the corrected ROI area is less than the first threshold, it is determined that the radiotherapy process needs to be adjusted.

5. A computer-readable storage medium, characterized in that: Used to store computer-readable programs or instructions, which, when executed by a processor, can implement the following steps: Acquiring historical radiotherapy image data of the subject to be treated, the historical radiotherapy image data comprising a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological movements; Acquiring real-time physiological motion information of the subject to be treated, and determining a plurality of real-time physiological motion phases of the real-time physiological motion information; Determine a historical physiological motion phase corresponding to the real-time physiological motion, and determine radiotherapy sub-image data corresponding to the real-time physiological motion according to the historical physiological motion phase; Obtain treatment fields in radiotherapy plans; determining a corrected region of interest in the radiotherapy sub-image data; Acquiring an overlapping area of ​​the treatment field and the overlapping portion of the correction region of interest; Determining whether the ratio of the overlapping area to the area of ​​the corrected ROI is greater than or equal to a first threshold; When the ratio of the overlap area to the corrected ROI area is less than the first threshold, it is determined that the radiotherapy process needs to be adjusted.

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