Application of litsea coreana extract in prevention and treatment of obesity and intestinal flora imbalance

Abstract

The invention discloses a new application of a litsea coreana extract, namely an application of the litsea coreana extract in preparation of medicines and functional foods for preventing and treating obesity and intestinal flora imbalance. Animal experiments verify that the litsea coreana extract is used for preventing and treating obesity, intestinal flora imbalance and other metabolic disorder diseases, and the result shows that the litsea coreana water extract has remarkable prevention and improvement effects on high fat diet induced obesity, intestinal flora imbalance and other metabolic disorder diseases. Meanwhile, the litsea coreana is a common tea drink, is high in safety, is harmless after being taken for a long time, and is relatively wide in distribution, and the raw materials are easy to obtain.

Description

technical field

[0001] The invention relates to the technical field of medicine or functional food, in particular to the application of eagle tea extract in preventing and treating obesity and intestinal flora imbalance. Background technique

[0002] Obesity is a disease in which body weight increases due to excessive accumulation of fat in the body. It is related to dietary habits, drugs, reduced exercise, and imbalance of intestinal flora. With the occurrence of obesity, it will cause a series of lipid metabolism disorders, leading to elevated blood lipid levels, hepatic steatosis and so on. In addition, obesity is closely related to a series of metabolic diseases such as type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver. With the easy availability of high-fat and high-calorie foods, the number of obese people has increased dramatically around the world, and obesity has become a growing public health problem. At present, the treatment methods for ob...

Examples

Embodiment

[0027]Example: Obesity in mice induced by a high-fat and high-calorie diet

[0028] The method of free high-fat diet was used to establish a high-fat diet-induced obesity model in mice, and the prevention and treatment effect of eagle tea extract on mouse obesity was observed through animal model experiments.

[0029] 1. Experimental materials

[0030] 1.1 Experimental animals

[0031] SPF male C57BL / 6J mice, Animal Experiment Center, Chongqing Medical University.

[0032] 1.2 Extract

[0033] The eagle tea water extract is mainly extracted and prepared with pure water. The specific method is as follows:

[0034] Dry the raw material of eagle tea to be extracted, and crush it into small pieces; add pure water, the ratio of solid to liquid (g / mL) is 1:20, carry out reflux extraction, the extraction time is 2h, and obtain the extract; the extract Filtrate with a fiber membrane to obtain the filtrate and filter residue extracted for the first time; repeat the second extractio...

technical field

[0001] The invention relates to the technical field of medicine or functional food, in particular to the application of eagle tea extract in preventing and treating obesity and intestinal flora imbalance. Background technique

[0002] Obesity is a disease in which body weight increases due to excessive accumulation of fat in the body. It is related to dietary habits, drugs, reduced exercise, and imbalance of intestinal flora. With the occurrence of obesity, it will cause a series of lipid metabolism disorders, leading to elevated blood lipid levels, hepatic steatosis and so on. In addition, obesity is closely related to a series of metabolic diseases such as type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver. With the easy availability of high-fat and high-calorie foods, the number of obese people has increased dramatically around the world, and obesity has become a growing public health problem. At present, the treatment methods for ob...

Examples

Embodiment

[0027]Example: Obesity in mice induced by a high-fat and high-calorie diet

[0028] The method of free high-fat diet was used to establish a high-fat diet-induced obesity model in mice, and the prevention and treatment effect of eagle tea extract on mouse obesity was observed through animal model experiments.

[0029] 1. Experimental materials

[0030] 1.1 Experimental animals

[0031] SPF male C57BL / 6J mice, Animal Experiment Center, Chongqing Medical University.

[0032] 1.2 Extract

[0033] The eagle tea water extract is mainly extracted and prepared with pure water. The specific method is as follows:

[0034] Dry the raw material of eagle tea to be extracted, and crush it into small pieces; add pure water, the ratio of solid to liquid (g / mL) is 1:20, carry out reflux extraction, the extraction time is 2h, and obtain the extract; the extract Filtrate with a fiber membrane to obtain the filtrate and filter residue extracted for the first time; repeat the second extractio...

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