A delivery device for a degradable biofilm that promotes endometrial regeneration

Abstract

The application belongs to the technical field of medical devices, and particularly relates to a delivery device of a degradable biological membrane for promoting endometrial regeneration, which comprises a sleeve, a push rod, a movable support and a control switch, the push rod is slidingly arranged in the hollow sleeve, the movable support and the control switch are respectively arranged at two ends of the push rod, the control switch is used for driving the movable support to open or close, when the push rod drives the movable support to be accommodated into the sleeve, the movable support is in a closed state, and when the push rod drives the movable support to extend out of the sleeve, the control switch can drive the movable support to open. Advantageous effects: the delivery device is convenient for delivering the uterine repair membrane into the uterine cavity and effectively protecting the uterine repair membrane, the uterine repair membrane is conveniently spread in the uterine cavity, and the uterine repair membrane is uniformly attached to the uterine wall by using water pressure.

Description

Technical Field

[0001] This invention belongs to the field of medical device technology, and in particular relates to a delivery device for a biodegradable biofilm that promotes endometrial regeneration. Background Technology

[0002] Data released by the National Population and Family Planning Commission shows that uterine-related lesions account for 10% to 15% of infertility among women of childbearing age in my country, with intrauterine problems causing infertility accounting for 7.3%. Endometrial problems are common in obstetrics and gynecology, including intrauterine adhesions and endometriosis. The most common clinical treatment is hysteroscopic surgery. Generally, membranous adhesions or fibromyalgia can be separated or surgically removed under hysteroscopy, combined with hormone therapy. However, post-treatment care is not ideal for preventing recurrence of intrauterine adhesions or for endometrial repair.

[0003] Current treatments for preventing intrauterine adhesion recurrence and addressing poor endometrial repair involve applying a uterine repair membrane to the entire uterine cavity after hysteroscopic surgery. For example, the uterine repair membrane disclosed in patent WO2014075388A1 is a tissue repair membrane that can also be used to repair pelvic floor dysfunction (including uterine repair). This repair membrane forms a physical barrier within the uterine cavity, preventing the recurrence of adhesions, and also promotes the repair of the functional and basal layers of the endometrium, accelerating the regeneration of damaged endometrium to achieve therapeutic goals. However, the unique structure of the uterus leads to difficulties in the delivery of the uterine repair membrane, challenges in its spreading within the uterine cavity, and uneven spreading. Summary of the Invention

[0004] To address the problems in existing technologies, such as obstructed delivery of the uterine repair membrane due to the unique structure of the uterus, difficulty in spreading the uterine repair membrane within the uterine cavity, and uneven spreading of the uterine repair membrane, this invention provides a biodegradable biomembrane delivery device that promotes endometrial regeneration.

[0005] To solve the above-mentioned technical problems, the technical solution adopted by the present invention is as follows: a delivery device for a biodegradable biofilm that promotes endometrial regeneration, comprising a cannula, a push rod, a movable support, and a control switch. The push rod is slidably disposed within the hollow cannula. The movable support and the control switch are respectively disposed at both ends of the push rod. The control switch is used to drive the movable support to open or close. When the push rod drives the movable support to be retracted into the cannula, the movable support is in a closed state. When the push rod drives the movable support to extend out of the cannula, the control switch can drive the movable support to open.

[0006] Preferably, the delivery device also includes a water pipe mounted on the push rod, with the outlet end of the water pipe located near the movable support and the inlet end located near the control switch. This delivery device uses the movable support to open the uterine repair membrane, and then uses the water pipe to flush liquid into the uterine cavity. The water flow effectively separates the uterine repair membrane from the movable support, and the water pressure ensures the uterine repair membrane adheres completely to the uterine wall.

[0007] Furthermore, the water inlet end of the water pipe is provided with a water connector, which is connected to a syringe or a uterine stimulator. This facilitates connection of the water pipe to existing syringes or uterine stimulators.

[0008] Furthermore, the syringe or uterine vasodilator is filled with physiological saline or uterine vasodilator fluid. Physiological saline or uterine vasodilator fluid will not cause uterine damage and can effectively protect the uterine cavity.

[0009] Preferably, the front end of the cannula has a storage space. When the push rod moves the movable support into the cannula, the movable support is located within the storage space. This facilitates the storage of the movable support and the uterine repair membrane wrapped around the movable support into the storage space.

[0010] Preferably, the sleeve is provided with a first locking member and a second locking member, and the push rod is provided with a positioning member. When the positioning member is engaged with the first locking member, the push rod is locked inside the sleeve, and the movable bracket extends out of the sleeve. When the positioning member is engaged with the second locking member, the push rod is locked inside the sleeve, and the movable bracket is retracted into the storage space. The positioning member, in conjunction with the first and second locking members respectively, locks the push rod at both positions, improving the operational stability and convenience of the conveying device.

[0011] Furthermore, the first locking member includes a first limiting hole, and the second locking member includes a second limiting hole. Both the first and second limiting holes are L-shaped and are located on the sleeve. A slide rail is formed along the length of the sleeve, and both ends of the slide rail communicate with the first and second limiting holes, respectively. The positioning member includes a positioning post, which slides sequentially along the first limiting hole, the slide rail, and the second limiting hole. The positioning member, the first locking member, and the second locking member have a simple and reliable structure, ingenious design, convenient operation, and low cost.

[0012] Furthermore, a plurality of guide blocks are fixedly arranged at intervals along the length of the push rod, and the guide blocks cooperate with the inner wall of the sleeve. This effectively prevents the push rod from wobbling radially in the sleeve, while improving the forward and backward sliding accuracy of the push rod.

[0013] Furthermore, the guide block is fixedly mounted on the push rod, and the positioning post is fixedly mounted on one of the guide blocks. This facilitates the installation of the guide block and the positioning post, and ensures a robust structure.

[0014] Preferably, the movable support includes multiple support rods, which are evenly arranged sequentially around the sliding direction of the push rod. The tail end of each support rod is hinged to the push rod. A pull wire is installed inside the push rod, and one end of the pull wire is hinged to multiple connecting rods. The tail ends of corresponding support rods are hinged to the connecting rods. The other end of the pull wire is connected to a control switch. The control switch is used to drive the pull wire to move closer to or away from the movable support. When the pull wire moves closer to the movable support, it drives the movable support to open, and the movable support gradually expands outward away from the sleeve. When the pull wire moves away from the movable support, it drives the movable support to close. The movable support opens or closes through multiple support rods, which can adapt to different cavity sizes. The support rods are simple and reliable to set up. The control switch controls the opening or closing of the movable support through the pull wire, making operation convenient and easy to control the size of the movable support opening.

[0015] Furthermore, the number of support rods is two. This delivery device works by using a movable support to expand the uterine repair membrane, and then flushing physiological saline or uterine engorgement fluid into the uterine cavity through a water pipe. The water pressure then completely adheres the uterine repair membrane to the uterine wall. Therefore, two support rods are sufficient for the operation, facilitating the installation of the movable support and reducing costs.

[0016] Preferably, the control switch is a handle, which includes a handle body, a fixed handle, and a movable handle. The fixed handle is integrally formed and fixedly connected to the handle body, the movable handle is rotatably connected to the fixed handle, the push rod is fixedly connected to the handle body, and the pull cable is fixedly connected to the movable handle. An existing operating handle can also be used, as long as it allows for tightening and loosening of the pull cable. The handle allows for more precise control of the opening angle of the movable support, which facilitates better spreading of the uterine repair membrane wrapped around the movable support into the uterine cavity.

[0017] Beneficial effects:

[0018] 1. The present invention provides a biodegradable biofilm delivery device for promoting endometrial regeneration. The movable support extends out of the sleeve and is in a closed state. The uterine repair membrane is then wrapped around the movable support and the water pipe. The movable support then drives the uterine repair membrane to be completely contained in the sleeve. The movable support end of the delivery device is then inserted into the bottom of the uterine cavity through the cervix, effectively protecting the uterine repair membrane from damage during the delivery process and greatly facilitating the delivery of the uterine repair membrane into the uterine cavity.

[0019] 2. The biodegradable biofilm delivery device for promoting endometrial regeneration of the present invention first extends the movable support out of the sleeve, so that the uterine repair membrane is completely exposed in the uterine cavity, and then the angle of opening of the movable support is more precisely controlled by the handle, which is conducive to better spreading the uterine repair membrane wrapped outside the movable support into the uterine cavity.

[0020] 3. The present invention provides a biodegradable biofilm delivery device that promotes endometrial regeneration. A water pipe flushes physiological saline or uterine lavage fluid into the uterine cavity. The water flow helps to better separate the uterine repair membrane from the movable support, and the water pressure helps to completely adhere the uterine repair membrane to the uterine wall. The uterine repair membrane spreads easily in the uterine cavity. The clever use of water pressure ensures that the uterine repair membrane adheres evenly and smoothly to the uterine wall, greatly shortening the operation time and significantly improving the success rate of the operation and the postoperative cure effect. Attached Figure Description

[0021] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the following description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0022] Figure 1 This is a side view schematic diagram of the biodegradable biofilm delivery device for promoting endometrial regeneration according to the present invention;

[0023] Figure 2 This is a side view schematic diagram of the movable support of the biodegradable biofilm delivery device for promoting endometrial regeneration according to the present invention.

[0024] Figure 3 This is an exploded schematic diagram of the biodegradable biofilm delivery device for promoting endometrial regeneration according to the present invention.

[0025] Figure 4 This is a three-dimensional structural schematic diagram of the biodegradable biofilm delivery device for promoting endometrial regeneration according to the present invention, wherein the movable support extends out of the placement space and is in a closed state;

[0026] Figure 5 This is a three-dimensional structural schematic diagram of the biodegradable biofilm delivery device for promoting endometrial regeneration according to the present invention, wherein the movable support is stored in the storage space and is in a closed state;

[0027] Figure 6 This is a three-dimensional structural schematic diagram of the biodegradable biofilm delivery device for promoting endometrial regeneration according to the present invention, wherein the movable support extends out of the placement space and is in an open state;

[0028] In the diagram: 1. Sleeve, 11. Storage space, 12. First limiting hole, 13. Second limiting hole, 14. Slide, 2. Push rod, 3. Water pipe, 31. Water inlet, 4. Movable bracket, 41. Support rod, 5. Handle, 51. Handle body, 52. Fixed handle, 53. Movable handle, 6. Positioning post, 7. Guide block, 8. Pull line, 9. Connecting rod. Detailed Implementation

[0029] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. The following description of at least one exemplary embodiment is merely illustrative and is in no way intended to limit the present invention or its application or use. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0030] Example

[0031] like Figures 1-6 As shown, a device for delivering a biodegradable biofilm that promotes endometrial regeneration includes a cannula 1, a push rod 2, a water pipe 3, a movable support 4, and a control switch. The push rod 2 is slidably disposed within the hollow cannula 1, and a storage space 11 is provided between the cannula 1 and the push rod 2. The storage space 11 is located at the front end of the cannula 1. The movable support 4 and the control switch are respectively disposed at both ends of the push rod 2. The control switch is used to drive the movable support 4 to open or close. When the push rod 2 drives the movable support 4 to be retracted into the storage space 11, the movable support 4 is in a closed state. When the push rod 2 drives the movable support 4 to extend out of the cannula 1, the control switch can drive the movable support 4 to open. The water pipe 3 is disposed on the push rod 2, with the outlet end of the water pipe 3 located near the movable support 4 and the inlet end of the water pipe 3 located near the control switch.

[0032] To facilitate locking of push rod 2 and ensure smooth sliding of push rod 2, in this embodiment, as follows: Figures 3-6 As shown, the sleeve 1 is provided with a first locking member and a second locking member, and the push rod 2 is provided with a positioning member. When the positioning member is engaged with the first locking member, the push rod 2 is locked inside the sleeve 1, and the movable bracket 4 extends out of the sleeve 1. When the positioning member is engaged with the second locking member, the push rod 2 is locked inside the sleeve 1, and the movable bracket 4 is retracted into the storage space 11. Specifically, in this embodiment, the first locking member includes a first limiting hole 12, and the second locking member includes a second limiting hole 13. Both the first limiting hole 12 and the second limiting hole 13 are formed on the sleeve 1. All are L-shaped, and a slide rail 14 is provided on the sleeve 1 along its length direction. The two ends of the slide rail 14 are respectively connected to the first limiting hole 12 and the second limiting hole 13. The positioning element includes a positioning post 6, which is slidably arranged along the first limiting hole 12, the slide rail 14 and the second limiting hole 13. Specifically, in this embodiment, a plurality of guide blocks 7 are fixedly arranged at intervals along the length direction of the push rod 2. The guide blocks 7 cooperate with the inner wall of the sleeve 1. In this embodiment, the guide blocks 7 are fixedly arranged on the push rod 2, and the positioning post 6 is fixedly arranged on one of the guide blocks 7.

[0033] To ensure that the movable support 4 can be adapted to different cavity sizes and to facilitate the operation of the movable support 4, such as Figures 1-3 As shown, the movable support 4 includes multiple support rods 41, which are evenly arranged sequentially around the sliding direction of the push rod 2. In this embodiment, there are two support rods 41. The tail end of each support rod 41 is hinged to the push rod 2. A pull wire 8 is provided inside the push rod 2. One end of the pull wire 8 is hinged to multiple connecting rods 9. The tail ends of corresponding sets of support rods 41 are hinged to connecting rods 9. The other end of the pull wire 8 is connected to a control switch. The control switch is used to drive the pull wire 8 to move closer to or away from the movable support 4. When the pull wire 8 moves closer to the movable support 4, it drives the movable support 4 to move closer to or away from the push rod 2. The bracket 4 opens, and the movable bracket 4 gradually expands outward away from the sleeve 1. When the pull wire 8 moves away from the movable bracket 4, it drives the movable bracket 4 to close. The control switch in this embodiment is a handle 5. The handle 5 includes a handle body 51, a fixed handle 52, and a movable handle 53. The fixed handle 52 is fixedly connected to the handle body 51 by integral molding. The movable handle 53 is rotatably connected to the fixed handle 52. The push rod 2 is fixedly connected to the handle body 51. The pull wire 8 is fixedly connected to the movable handle 5. The handle 5 is an existing operating handle 5 that can tighten and loosen the pull wire 8.

[0034] To facilitate the introduction of liquid into water pipe 3, in this embodiment, as follows: Figures 3-6 As shown, the water inlet end of the water pipe 3 is provided with a water inlet head 31, which is connected to the syringe or the uterine ovulation device; the syringe or the uterine ovulation device is filled with physiological saline or uterine ovulation fluid. In this embodiment, a syringe is used, and the syringe is filled with physiological saline.

[0035] The working principle is as follows:

[0036] First, the positioning pin 6 is positioned inside the first limiting hole 12. At this time, the push rod 2 is locked inside the sleeve 1, the movable bracket 4 extends out of the sleeve 1, and the movable bracket 4 is in the closed state. Figure 4 As shown, the uterine repair membrane is then wrapped around the movable support 4 and the water pipe 3; the positioning post 6 is then disengaged from the first limiting hole 12, and the push rod 2 slides along the sleeve 1, simultaneously driving the positioning post 6 to slide along the slide rail 14 until the positioning post 6 slides into the second limiting hole 13. At this point, the push rod 2 is locked inside the sleeve 1, and the movable support 4 drives the uterine repair membrane to be completely stored in the storage space 11, as shown. Figure 5As shown; then the movable support 4 end of the delivery device is inserted into the bottom of the uterine cavity through the cervix; then the sleeve 1 is rotated, so that the positioning post 6 is disengaged from the second limiting hole 13, and the sleeve 1 is pulled back, while the positioning post 6 slides along the slide rail 14 until the positioning post 6 slides into the first limiting hole 12. At this time, the push rod 2 is locked in the sleeve 1, and the movable support 4 extends out of the sleeve 1, so that the uterine repair membrane is completely exposed in the uterine cavity; then the movable handle 5 is rotated, and the movable handle 5 drives the pull wire 8 to move closer to the movable support 4, which drives the movable support 4 to open, as shown. Figure 6 As shown, the uterine repair membrane wrapped around the movable support 4 is completely spread into the uterine cavity; then, the saline solution in the syringe is flushed into the uterine cavity through the water pipe 3, and the water pressure is used to completely adhere the uterine repair membrane to the uterine wall; then, the movable handle 5 is rotated to reset, and the movable handle 5 drives the pull wire 8 to move away from the movable support 4, which drives the movable support 4 to close and reset. Then, the delivery device is withdrawn from the uterine cavity, and the placement of the uterine repair membrane is completed.

[0037] The above are merely preferred embodiments of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A device for delivering a biodegradable biofilm that promotes endometrial regeneration, characterized in that: The device includes a sleeve (1), a push rod (2), a movable bracket (4), and a control switch. The push rod (2) is slidably disposed inside the hollow sleeve (1). The movable bracket (4) and the control switch are respectively disposed at both ends of the push rod (2). The control switch is used to drive the movable bracket (4) to open or close. When the push rod (2) drives the movable bracket (4) to be stored inside the sleeve (1), the movable bracket (4) is in a closed state. When the push rod (2) drives the movable bracket (4) to extend out of the sleeve (1), the control switch can drive the movable bracket (4) to open. The conveying device also includes a water pipe (3), which is mounted on the push rod (2). The water outlet of the water pipe (3) is located near the movable support (4), and the water inlet of the water pipe (3) is located near the control switch. The front end of the sleeve (1) has a storage space (11). When the push rod (2) drives the movable bracket (4) to be stored in the sleeve (1), the movable bracket (4) is in the storage space (11). First, the movable support (4) extends out of the sleeve (1), and the movable support (4) is in a closed state. Then, the uterine repair membrane is wrapped around the movable support (4) and the water pipe (3). Then, the movable support (4) drives the uterine repair membrane to be completely stored in the storage space (11). Then, the end of the movable support (4) of the delivery device is inserted into the bottom of the uterine cavity through the cervix. Then, the movable support (4) extends out of the sleeve (1), so that the uterine repair membrane is completely exposed in the uterine cavity. Then, the movable support (4) is opened by controlling the switch, so that the uterine repair membrane wrapped outside the movable support (4) is completely spread in the uterine cavity; then, physiological saline is flushed into the uterine cavity through the water pipe (3), and the water pressure is used to completely adhere the uterine repair membrane to the uterine wall; Then, the movable support (4) is driven to close and reset by the control switch, and then the delivery device is removed from the uterine cavity.

2. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 1, characterized in that: The water inlet end of the water pipe (3) is provided with a water inlet head (31), which is connected to the syringe or the water inlet head (31) is connected to the uterine distiller.

3. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 2, characterized in that: The syringe or distiller is filled with physiological saline or distiller's fluid.

4. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 1, 2, or 3, characterized in that: The sleeve (1) is provided with a first locking member and a second locking member, and the push rod (2) is provided with a positioning member. When the positioning member is engaged with the first locking member, the push rod (2) is locked inside the sleeve (1), and the movable bracket (4) extends out of the sleeve (1). When the positioning member is engaged with the second locking member, the push rod (2) is locked inside the sleeve (1), and the movable bracket (4) is stored in the storage space (11).

5. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 4, characterized in that: The first locking member includes a first limiting hole (12), and the second locking member includes a second limiting hole (13). The first limiting hole (12) and the second limiting hole (13) are both opened on the sleeve (1) and are both L-shaped. A slide (14) is opened on the sleeve (1) along its length direction. The two ends of the slide (14) are respectively connected to the first limiting hole (12) and the second limiting hole (13). The positioning member includes a positioning post (6). The positioning post (6) is slidably arranged along the first limiting hole (12), the slide (14) and the second limiting hole (13).

6. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 5, characterized in that: The push rod (2) is provided with a number of guide blocks (7) fixedly arranged at intervals along its length direction, and the guide blocks (7) cooperate with the inner wall of the sleeve (1).

7. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 6, characterized in that: The guide block (7) is fixedly mounted on the push rod (2), and the positioning post (6) is fixedly mounted on one of the guide blocks (7).

8. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 1, characterized in that: The movable support (4) includes multiple support rods (41), which are arranged evenly in sequence around the sliding direction of the push rod (2). The tail end of the support rod (41) is hinged to the push rod (2). A pull wire (8) is provided inside the push rod (2). One end of the pull wire (8) is hinged to multiple connecting rods (9). The tail end of the support rod (41) and the connecting rod (9) of a corresponding group are hinged. The other end of the pull wire (8) is connected to a control switch. The control switch is used to drive the pull wire (8) to move closer to or away from the movable support (4). When the pull wire (8) moves closer to the movable support (4), it drives the movable support (4) to open, and the movable support (4) gradually expands outward away from the sleeve (1). When the pull wire (8) moves away from the movable support (4), it drives the movable support (4) to close.

9. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 8, characterized in that: The number of support rods (41) is two.

10. The device for delivering a biodegradable biofilm that promotes endometrial regeneration according to claim 8 or 9, characterized in that: The control switch is a handle (5), which includes a handle body (51), a fixed handle (52) and a movable handle (53). The fixed handle (52) is fixedly connected to the handle body (51) by integral molding. The movable handle (53) is rotatably connected to the fixed handle (52). The push rod (2) is fixedly connected to the handle body (51). The pull cable (8) is fixedly connected to the movable handle (5).

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