A desktop filling and capping machine

Abstract

A desktop filling and capping machine includes a capping module, which comprises a capping conveying assembly and a capping lifting shaft assembly. The module also includes a first capping component for capping vials or a second capping component for capping pre-filled syringes. The capping lifting shaft assembly has a first capping component mounting section and a second capping component mounting section, and either the first or second capping component is detachably mounted on the shaft assembly. When capping vials, the first capping component is mounted on its mounting section, and the capping lifting shaft assembly drives the first capping component to rise, fall, and rotate, thereby capping the vial from the capping conveying assembly onto the vial. When capping pre-filled syringes, the second capping component is mounted on its mounting section, and the capping lifting shaft assembly drives the second capping component to rise, fall, and rotate, thereby capping the vial from the capping conveying assembly onto the pre-filled syringe. This machine is adaptable to different types of packaging materials.

Description

Technical Field

[0001] This invention relates to food and pharmaceutical packaging equipment, and more particularly to a desktop filling and capping machine. Background Technology

[0002] Currently, desktop filling and capping machines for small-batch clinical trials and Phase I and IIa clinical trials of injectable drugs generally have the following shortcomings: 1) The manual workload and labor intensity are high during the filling, capping and crimping processes; 2) Manual weighing and recording make it difficult to ensure the accuracy of the filling volume; 3) Poor compatibility between different types of packaging materials (such as vials, pre-filled syringes and cartridges) requires the preparation of multiple production systems, which increases costs. Summary of the Invention

[0003] The technical problem to be solved by the present invention is to overcome the shortcomings of the prior art and provide a desktop filling and capping machine that is conducive to improving the degree of automation and can adapt to different types of packaging materials.

[0004] To solve the above-mentioned technical problems, the present invention adopts the following technical solution:

[0005] A desktop filling and capping machine includes a capping module, which includes a capping conveying assembly and a capping lifting shaft assembly. The capping module also includes a first capping assembly for capping vials or a second capping assembly for capping pre-filled syringes and cartridges. The capping lifting shaft assembly is provided with a first capping assembly mounting part and a second capping assembly mounting part. The first capping assembly or the second capping assembly is detachably mounted on the capping lifting shaft assembly.

[0006] As a further improvement to the above technical solution, it also includes a conveying module, a filling module, and a capping module. The first stopper assembly is detachably mounted on the stopper lifting shaft assembly. The filling module, the stopper module, and the capping module are arranged sequentially and detachably connected along the conveying direction of the conveying module. Alternatively, the second stopper assembly is detachably mounted on the stopper lifting shaft assembly. The filling module and the stopper module are arranged sequentially and detachably connected along the conveying direction of the conveying module.

[0007] As a further improvement to the above technical solution: the insert lifting shaft assembly includes a first lifting shaft and a second lifting shaft. The second insert assembly includes a first rocker arm disposed on the first lifting shaft, a vacuum insert sleeve disposed on the first rocker arm, a second rocker arm disposed on the second lifting shaft, and a top rod disposed on the second rocker arm. The top rod is located above the vacuum insert sleeve and has a sealing sleeve that cooperates with the vacuum insert sleeve on its outer periphery.

[0008] As a further improvement to the above technical solution: the first swing arm is sleeved on the first lifting shaft, the first lifting shaft has a protrusion on its side, and the first swing arm has a first locking block and a second locking block on both sides of the protrusion, and the first locking block and the second locking block are connected by fasteners.

[0009] As a further improvement to the above technical solution: both the first locking block and the second locking block are engaged with the wedge surface of the protrusion.

[0010] As a further improvement to the above technical solution: the first lifting shaft is a hollow shaft, and the second lifting shaft passes through the first lifting shaft.

[0011] As a further improvement to the above technical solution: the first insert assembly includes a third swing arm and a vacuum insert rod disposed on the third swing arm, wherein the third swing arm is disposed on the first lifting shaft or the second lifting shaft.

[0012] As a further improvement to the above technical solution: the filling module includes a medicine bag support, a filling pump, a filling lifting shaft, a filling swing arm on the filling lifting shaft, and a filling needle on the filling swing arm, wherein the filling pump is connected to the filling needle.

[0013] As a further improvement to the above technical solution, the filling module also includes a weighing component.

[0014] As a further improvement to the above technical solution: the capping module includes a cap feeding hopper, a cap hanging assembly, a capping lifting shaft, and a capping swing rod disposed on the capping lifting shaft. The capping swing rod is provided with a capping head and a capping knife.

[0015] Compared with the prior art, the advantages of the present invention are as follows: The desktop filling and capping machine disclosed in the present invention includes a capping lifting shaft assembly, which has a first capping component mounting part and a second capping component mounting part. When capping vials is required, the first capping component is installed in the first capping component mounting part, and the capping lifting shaft assembly drives the first capping component to move up and down and rotate, thereby adding the rubber cap from the capping component to the vial. When capping pre-filled syringes or cartridges is required, the first capping component is removed from the capping lifting shaft assembly, and the second capping component is installed in the second capping component mounting part. The capping lifting shaft assembly drives the second capping component to move up and down and rotate, thereby adding the rubber cap from the capping component to the pre-filled syringe or cartridge. This improves the degree of automation and can adapt to different types of packaging materials. Attached Figure Description

[0016] Figure 1 This is a top view of the desktop filling and capping machine of the present invention used for vial filling production.

[0017] Figure 2 This is a top view of the desktop filling and capping machine of the present invention used for pre-filled needle filling production.

[0018] Figure 3 This is a three-dimensional structural diagram of the external structure of the filling module in this invention.

[0019] Figure 4 This is a three-dimensional structural diagram of the filling module in this invention.

[0020] Figure 5 This is a three-dimensional structural diagram of the external structure of the first embodiment of the insert module in this invention.

[0021] Figure 6 This is a three-dimensional structural diagram of the internal structure of the insert module in the first embodiment of the present invention.

[0022] Figure 7 This is a cross-sectional view of the internal structure of the first embodiment of the insert module in this invention.

[0023] Figure 8 This is a three-dimensional structural diagram of the external structure of the second embodiment of the insert module in this invention.

[0024] Figure 9 This is a three-dimensional structural diagram of the internal structure of the second embodiment of the insert module in this invention.

[0025] Figure 10 This is a cross-sectional view of the internal structure of the second embodiment of the insert module in this invention.

[0026] Figure 11 This is a schematic diagram of the locking block in this invention.

[0027] Figure 12 This is a three-dimensional structural diagram of the external structure of the capping module in this invention.

[0028] Figure 13 This is a three-dimensional structural diagram of the internal structure of the capping module in this invention.

[0029] Figure 14 This is a three-dimensional structural diagram of the disassembled state of the filling module in this invention.

[0030] Figure 15 This is a three-dimensional structural diagram of the decomposition state of the present invention during vial filling production.

[0031] Figure 16 This is an enlarged view of the connection structure between the modules in this invention.

[0032] The labels in the diagram represent: 1. Conveying module; 11. Connecting plate; 2. Filling module; 21. Medicine bag support; 22. Filling pump; 23. Filling lifting shaft; 24. Filling swing arm; 25. Filling needle; 26. Weighing assembly; 27. Mounting base plate; 28. Positioning pin; 3. Stoppering module; 31. First stoppering assembly; 32. Third swing arm; 33. Vacuum stoppering rod; 4. Second stoppering assembly; 41. First lifting shaft; 411. Protrusion; 42. First swing arm. 421. First locking block; 422. Second locking block; 423. Fastener; 43. Vacuum stopper sleeve; 44. Second lifting shaft; 45. Second swing rod; 46. Top rod; 47. Sealing sleeve; 5. Capping module; 51. Capping lifting shaft; 52. Capping swing rod; 53. Capping head; 54. Crimping knife; 55. Cap sorting hopper; 56. Cap hanging assembly; 6. Stopper separating component; 7. Stopper sorting hopper; 81. Vial bottle placing mold; 82. Pre-filled needle bottle placing mold. Detailed Implementation

[0033] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0034] like Figures 5 to 10 As shown, the desktop filling and capping machine of this embodiment includes a capping module 3. The capping module 3 includes a capping conveying assembly (for example, using a capping hopper 7 to sort and convey the rubber caps to a capping distribution assembly 6, and then adding the rubber caps to the packaging material from the capping distribution assembly 6) and a capping lifting shaft assembly. The capping module 3 also includes a first capping assembly 31 for capping vials or a second capping assembly 4 for capping pre-filled syringes and cartridges. The capping lifting shaft assembly is provided with a first capping assembly mounting part and a second capping assembly mounting part. The first capping assembly 31 or the second capping assembly 4 is detachably mounted on the capping lifting shaft assembly.

[0035] When it is necessary to cap vials, the first capping assembly 31 is installed on the first capping assembly mounting part. The capping lifting shaft assembly drives the first capping assembly 31 to move up, down, and rotate, thereby adding the rubber stopper delivered by the capping assembly to the vial on the vial placement mold 81. When it is necessary to cap pre-filled syringes or cartridges, the first capping assembly 31 is removed from the capping lifting shaft assembly, and the second capping assembly 4 is installed on the second capping assembly mounting part. The capping lifting shaft assembly drives the second capping assembly 4 to move up, down, and rotate, thereby adding the rubber stopper delivered by the capping assembly to the pre-filled syringe or cartridge on the pre-filled syringe placement mold 82. This improves the level of automation and can adapt to different types of packaging materials. The first capping assembly 31 and the second capping assembly 4 share the capping assembly and the capping lifting shaft assembly, which helps to reduce equipment costs.

[0036] like Figures 1 to 4 and Figures 11 to 13As shown, further, in this embodiment, the desktop filling and capping machine also includes a conveying module 1, a filling module 2, and a capping module 5. The first capping component 31 is detachably installed on the capping lifting shaft assembly. The filling module 2, the capping module 3, and the capping module 5 are arranged sequentially along the conveying direction of the conveying module 1 and are detachably connected. Alternatively, the second capping component 4 is detachably installed on the capping lifting shaft assembly. The filling module 2 and the capping module 3 are arranged sequentially along the conveying direction of the conveying module 1 and are detachably connected. When vials need to be filled, capped, and crimped, the conveying module 1, filling module 2, capping module 3, and crimping module 5 are combined, and the first capping assembly 31 is installed on the capping lifting shaft assembly. The conveying module 1 then moves the vials between the filling module 2, capping module 3, and crimping module 5. When vials or pre-filled syringes need to be filled and capped, the conveying module 1, filling module 2, and capping module 3 are combined, and the second capping assembly 4 is installed on the capping lifting shaft assembly. The conveying module 1 then moves the vials or pre-filled syringes between the filling module 2 and capping module 3. The connections and disassemblies between the modules can be achieved using methods such as locating pins, threaded fasteners, and snap-fits, ensuring reliable connections and convenient assembly / disassembly.

[0037] Furthermore, in this embodiment, the stopper lifting shaft assembly includes a first lifting shaft 41 and a second lifting shaft 44. The second stopper assembly 4 includes a first rocker arm 42 disposed on the first lifting shaft 41, a vacuum stopper sleeve 43 disposed on the first rocker arm 42, a second rocker arm 45 disposed on the second lifting shaft 44 (correspondingly, the installation positions of the first rocker arm 42 and the second rocker arm 45 on the first lifting shaft 41 and the second lifting shaft 44 are the aforementioned second stopper assembly mounting portions), and a top rod 46 disposed on the second rocker arm 45. The top rod 46 is located above the vacuum stopper sleeve 43 and has a sealing sleeve 47 that cooperates with the vacuum stopper sleeve 43 on its outer periphery. When it is necessary to stopper the pre-filling needle or cartridge bottle on the pre-filling needle placement mold 82, the first lifting shaft 41 and the second lifting shaft 44 respectively drive the push rod 46 and the vacuum stoppering sleeve 43 to rotate to the stoppering component 6. Then, the second lifting shaft 44 drives the push rod 46 to descend, pushing the rubber stopper from the stoppering component 6 into the vacuum stoppering sleeve 43. Then, the push rod 46 rises to reset, and the vacuum stoppering sleeve 43 and the push rod 46 rotate to above the pre-filling needle. The first lifting shaft 41 drives the vacuum stoppering sleeve 43 to descend and contact the pre-filling needle. Then, the sealing sleeve 47 descends and contacts the vacuum stoppering sleeve 43 to form a seal. The vacuum stoppering sleeve 43 evacuates the pre-filling needle. After that, the push rod 46 descends and pushes the rubber stopper into the pre-filling needle. The vacuum stoppering sleeve 43 then breaks the vacuum, and the rubber stopper slides down to the liquid surface under the action of the internal and external pressure difference. The structure is simple and the operation is reliable. The rotation and lifting movements of the first lifting shaft 41 and the second lifting shaft 44 can be achieved by, for example, a motor or a linear module, which will not be described in detail here.

[0038] Furthermore, in this embodiment, the first rocker arm 42 is sleeved on the first lifting shaft 41. The first lifting shaft 41 has a protrusion 411 on its side. The first rocker arm 42 has a first locking block 421 and a second locking block 422 on both sides of the protrusion 411. The first locking block 421 and the second locking block 422 are connected by fasteners 423 (fasteners 423 can be screws, bolts, clips, etc.). By connecting the first locking block 421 and the second locking block 422 into a whole using fasteners 423, the protrusion 411 can be locked, thereby achieving reliable fixation of the first rocker arm 42 on the first lifting shaft 41, avoiding loosening during reciprocating rotation. The structure is simple, reliable, and easy to assemble and disassemble.

[0039] In a preferred embodiment, both the first locking block 421 and the second locking block 422 are engaged with the wedge surface of the protrusion 411. As the first locking block 421 and the second locking block 422 move closer to the protrusion 411, the protrusion 411 can be gradually clamped, effectively preventing the first swing rod 42 from rotating relative to the first lifting shaft 41. The structure is reasonable and has good reliability.

[0040] In a preferred embodiment, the first lifting shaft 41 is a hollow shaft, and the second lifting shaft 44 is inserted into the first lifting shaft 41, making the insert module 3 more compact and occupying less space.

[0041] In this embodiment, the first stopper assembly 31 includes a third swing arm 32 and a vacuum stopper rod 33 mounted on the third swing arm 32. The third swing arm 32 is mounted on the second lifting shaft 44 (correspondingly, the mounting position of the third swing arm 32 on the second lifting shaft 44 is the mounting part of the first stopper assembly). When it is necessary to stopper the vials on the vial placement mold 81, the second lifting shaft 44 drives the vacuum stopper rod 33 to rotate to the stoppering component 6. The vacuum stopper rod 33 uses vacuum to suck up the rubber stopper, and then rotates to the top of the vial. The second lifting shaft 44 then drives the vacuum stopper rod 33 to descend, breaking the vacuum and thus adding the rubber stopper to the vial. The structure is simple and reliable. Of course, in other embodiments, the third swing arm 32 can also be mounted on the first lifting shaft 41, which can also realize the rotation and lifting movement of the vacuum stopper rod 33, thereby completing the stoppering of the vial.

[0042] In this embodiment, the filling module 2 includes a medicine bag support 21, a filling pump 22, a filling lifting shaft 23, a filling swing arm 24 mounted on the filling lifting shaft 23, and a filling needle 25 mounted on the filling swing arm 24. The filling pump 22 is connected to the filling needle 25. In a preferred embodiment, the filling module 2 also includes a weighing component 26. The filling pump 22 quantitatively fills the medicine bag into the packaging material; the filling lifting shaft 23 drives the filling needle 25 to move up and down and rotate. Preferably, the filling and lifting can be carried out simultaneously, and a sampling and weighing method can be used. The packaging material is manually placed on the weighing component 26, and the filling needle 25 rotates to be above the weighing component 26, realizing simultaneous filling and weighing, which helps to ensure the accuracy of the filling amount.

[0043] In this embodiment, the capping module 5 includes a cap sorting hopper 55, a cap hanging assembly 56, a capping lifting shaft 51, and a capping swing rod 52 mounted on the capping lifting shaft 51. The capping swing rod 52 is equipped with a capping head 53 and a capping cutter 54. The cap sorting hopper 55 sorts and outputs the bottle caps in an orderly manner, the cap hanging assembly 56 hangs the bottle caps on the bottle body, and the capping lifting shaft 51 drives the capping head 53 and the capping cutter 54 to move up and down and rotate, thus completing the capping process.

[0044] like Figure 14 As shown, the filling module 2 of this invention comprises two main parts according to its assembly form: a functional part and a supporting part. The functional part integrates components such as the liquid bag support 21, the filling pump 22, the filling lifting shaft 23, the filling swing arm 24, and the filling needle 25, which are used to complete the filling function. The supporting part is used to arrange the vial placement mold 81 or the pre-filled needle placement mold 82. The functional part is provided with a mounting base plate 27, on which the control components and pneumatic components of the filling module 2 can be mounted, which can save space in the functional part and facilitate disassembly and assembly. The mounting base plate 27 is provided with positioning pins 28. The supporting part is positioned and installed on the mounting base plate 27 by cooperating with the positioning pins 28 through positioning holes. After installation, the structure is as follows. Figure 3 As shown, the filling module 2 can be used as a standalone unit for filling vials, pre-filled syringes, or cartridge bottles. Preferably, the vial placement mold 81, the pre-filled syringe placement mold 82, and the supporting part are also positioned by positioning pins 28 for easy replacement. The stopper module 3 and the capping module 5 are assembled in the same way as the filling module 2, and will not be described again.

[0045] like Figure 15 and 16 As shown, when the filling module 2, the stopper module 3, and the capping module 5 need to be assembled into a production line, the load-bearing parts of each component are disassembled, and their respective mounting base plates 27 are connected in pairs to form a whole through the connecting plates 11. Finally, the conveying module 11 is positioned and installed with each module through the positioning holes and positioning pins 28. There is no need to rearrange the control components, pneumatic components, etc. of each module. After the installation is completed, the structure is as follows. Figure 1 As shown.

[0046] While the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the invention. Any person skilled in the art can make many possible variations and modifications to the technical solutions of the present invention, or modify them into equivalent embodiments, without departing from the scope of the present invention. Therefore, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention, without departing from the scope of the present invention, should fall within the protection scope of the present invention.

Claims

1. A desktop filling and capping machine, comprising a capping module (3), wherein the capping module (3) includes a capping conveying assembly and a capping lifting shaft assembly, characterized in that: The stopper lifting shaft assembly is provided with a first stopper assembly mounting part and a second stopper assembly mounting part. When used for stoppering vials, the stoppering module (3) further includes a first stopper assembly (31), which is detachably mounted on the stopper lifting shaft assembly. The stopper lifting shaft assembly can drive the first stopper assembly (31) to move up and down and rotate, for adding the rubber stopper delivered by the stopper delivery assembly to the vial. When used for stoppering pre-filled syringes and cartridge vials, the stoppering module (3) further includes a second stopper assembly (4), which is detachably mounted on the stopper lifting shaft assembly. The stopper lifting shaft assembly can drive the second stopper assembly (4) to move up and down and rotate, for adding the rubber stopper delivered by the stopper delivery assembly to the pre-filled syringe or cartridge vial. The stopper lifting shaft assembly includes a first lifting shaft (41) and a second lifting shaft (44). The second stopper assembly (4) includes a first lifting shaft (41) and a second lifting shaft (44). A first rocker arm (42) on a first lifting shaft (41), a vacuum plugging sleeve (43) on the first rocker arm (42), a second rocker arm (45) on a second lifting shaft (44), and a top rod (46) on the second rocker arm (45). The top rod (46) is located above the vacuum plugging sleeve (43) and has a sealing sleeve (47) on its outer periphery that cooperates with the vacuum plugging sleeve (43), so that the vacuum plugging sleeve (43) The first plugging assembly (31) and the top rod (46) are rotatable to the plug delivery assembly, and the plug is pushed from the plug delivery assembly into the vacuum plugging sleeve (43) through the top rod (46); the first plugging assembly (31) includes a third rocker arm (32) and a vacuum plugging rod (33) disposed on the third rocker arm (32), the third rocker arm (32) is disposed on the first lifting shaft (41) or the second lifting shaft (44), and the vacuum plugging rod (33) uses vacuum to suck up the plug.

2. The desktop filling and capping machine according to claim 1, characterized in that: It also includes a conveying module (1), a filling module (2), and a capping module (5). When filling, capping, and crimping vials, the first capping assembly (31) is installed on the capping lifting shaft assembly. The filling module (2), the capping module (3), and the capping module (5) are arranged sequentially along the conveying direction of the conveying module (1) and are detachably connected. When filling and capping cartridges and pre-filled needles, the second capping assembly (4) is installed on the capping lifting shaft assembly. The filling module (2) and the capping module (3) are arranged sequentially along the conveying direction of the conveying module (1) and are detachably connected.

3. The desktop filling and capping machine according to claim 1, characterized in that: The first swing arm (42) is sleeved on the first lifting shaft (41). The first lifting shaft (41) has a protrusion (411) on its side. The first swing arm (42) has a first locking block (421) and a second locking block (422) on both sides of the protrusion (411). The first locking block (421) and the second locking block (422) are connected by fasteners (423).

4. The desktop filling and capping machine according to claim 3, characterized in that: The first locking block (421) and the second locking block (422) both engage with the wedge surface of the protrusion (411).

5. The desktop filling and capping machine according to claim 1, characterized in that: The first lifting shaft (41) is a hollow shaft, and the second lifting shaft (44) passes through the first lifting shaft (41).

6. The desktop filling and capping machine according to claim 2, characterized in that: The filling module (2) includes a medicine bag support (21), a filling pump (22), a filling lifting shaft (23), a filling swing rod (24) on the filling lifting shaft (23), and a filling needle (25) on the filling swing rod (24). The filling pump (22) is connected to the filling needle (25).

7. The desktop filling and capping machine according to claim 6, characterized in that: The filling module (2) also includes a weighing component (26).

8. The desktop filling and capping machine according to claim 2, characterized in that: The capping module (5) includes a capping bucket (55), a cap hanging assembly (56), a capping lifting shaft (51), and a capping swing rod (52) provided on the capping lifting shaft (51). The capping swing rod (52) is provided with a capping head (53) and a capping knife (54).

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