A detection unit for an implantable analyte sensor

Abstract

The application provides a detection unit of an implantable analyte sensor, which comprises an implantable analyte sensor and a fixing part of the implantable analyte sensor, wherein the implantable analyte sensor comprises a front surface and a back surface, the upper end of the front surface and the back surface is respectively provided with an electrode interface, and the lower end of the front surface and the back surface is respectively provided with an electrode area; the fixing part comprises a conductive channel and a through hole. The detection unit can distribute more electrodes in a limited area, the fixing part for fixing the sensor has a small structure, and the preparation process is simple.

Description

[0001] The present application is a divisional application of patent application entitled: Fixing member and sensor system for implantable analyte sensor, patent application number: 201811348478.8. TECHNICAL FIELD

[0002] The present application relates to a fixing member for an implantable analyte sensor and an implantable analyte sensor system comprising the fixing member, and belongs to the technical field of electroanalytical chemical detection. BACKGROUND

[0003] For the past analyte detection technology, taking patients with diabetes as an example, they need to detect the glucose content in the blood regularly, and then use colorimetric method, electrochemical analysis method or optical detection method to detect after collecting blood by puncture needle to pierce the skin. These methods are not only cumbersome but also increase the burden of patients. Therefore, in order to solve the above problems, and in order to continuously detect the change of the concentration of the analyte in the body, many devices for continuous analyte detection have been developed.

[0004] In the prior art, the method of electrochemical analysis is generally used. For this purpose, the sensor for detecting the analyte is provided with at least a working electrode, a counter electrode and a reference electrode. These electrodes are generally on the same side or distributed on opposite sides. The patents with publication numbers CN102665549B, CN104887242A and CN103750819B disclose a method of distributing electrodes on the same side of the sensor. This distribution method needs to distribute multiple electrodes in a limited area, which undoubtedly increases the process difficulty and technical requirements. The patents with publication numbers CN102469964B and US9795326B2 disclose a method of distributing electrodes on both sides of the sensor. This method can reduce the process difficulty of the sensor manufacturing, but the fixing member for fixing the sensor needs to be provided with electrical contacts on different sides, thus increasing the complexity of the fixing member or the difficulty of installing the sensor. SUMMARY

[0005] In view of the deficiencies of the prior art, the present application provides a fixing member for an implantable analyte sensor, which is particularly suitable for a sensor with double-sided microelectrodes. The basic idea of the present application is to provide a first end portion on the side facing the microelectrode (counter electrode), which is electrically connected to the interface of the counter electrode. At the same time, a second end portion is electrically connected to the first end portion, and the second end portion is connected to the interface corresponding to the sensor current data generating device, so that the sensor current data generating device can be connected to the microelectrode of the sensor with double-sided structure, thereby performing analyte testing.

[0006] The present application aims to provide a fixing member for an implantable analyte sensor, for a sensor with double-sided microelectrodes, the fixing member comprising a support part, a receiving part, a conductive path and a through hole; the receiving part is composed of a receiving part top, a receiving part sidewall, a receiving part bottom and a receiving part inner wall, the support part is connected to the receiving part bottom to form a receiving part bottom platform; the through hole is located on the support part and opens at one end on the receiving part bottom platform; the conductive path is located on the receiving part; the conductive path comprises at least two end parts.

[0007] In some preferred embodiments, the conductive path comprises a first end part and a second end part, and the second end part is electrically connected to the first end part.

[0008] In some preferred embodiments, the conductive path penetrates the receiving part.

[0009] In some preferred embodiments, the conductive path is located on the outer surface of the receiving part.

[0010] In some preferred embodiments, the conductive path penetrates the receiving part in part and is located on the outer surface of the receiving part in part.

[0011] In some preferred embodiments, the receiving part has a conductive channel for accommodating the conductive path.

[0012] In some preferred embodiments, the first end part is located on the inner wall of the receiving part, and the second end part is located on the top or sidewall of the receiving part.

[0013] In some preferred embodiments, the conductive path further comprises a third end part located on the receiving part; the third end part is electrically connected to the second end part and the first end part.

[0014] In some preferred embodiments, one to three grooves are provided on the receiving part; the grooves are located on the inner wall or bottom of the receiving part.

[0015] In some preferred embodiments, the fixing member further comprises a conductive sheet located on the receiving part; the conductive sheet is electrically connected to the end part of the conductive path.

[0016] In some preferred embodiments, a sealing ring is further included, which surrounds the sidewall of the support part.

[0017] In some preferred embodiments, a connecting part is further included, which is connected to the support part.

[0018] In another aspect, the present application further provides an implantable analyte sensor system, comprising a detection unit, a signal transmission device, a data processing unit;

[0019] The detection unit and the signal transmission device are fixed in a housing, and a power supply is further provided in the housing for supplying power to the electronic components in the housing;

[0020] The detection unit comprises an implantable analyte sensor, a fixing member for fixing the implantable analyte sensor according to the present application, and a sensor current data generating device.

[0021] Specifically, the fixing member comprises a support part, a receiving part, a conductive path and a through hole; the receiving part is composed of a receiving part top, a receiving part sidewall, a receiving part bottom and a receiving part inner wall, the support part is connected to the receiving part bottom to form a receiving part bottom platform; the through hole is located on the support part and has one end opening on the receiving part bottom platform; the conductive path is located on the receiving part; the conductive path comprises at least two end parts.

[0022] In some preferred embodiments, the fixing member is fixed on the housing base through a connecting part connected to the support part.

[0023] In some preferred embodiments, the conductive path comprises a first end part and a second end part, and the second end part is electrically connected to the first end part.

[0024] In some preferred embodiments, the conductive path penetrates the receiving part.

[0025] In some preferred embodiments, the conductive path is located on the outer surface of the receiving part.

[0026] In some preferred embodiments, a part of the conductive path penetrates the receiving part, and another part is located on the outer surface of the receiving part.

[0027] In some preferred embodiments, the receiving part has a conductive channel for accommodating the conductive path.

[0028] In some preferred embodiments, the first end part is located on the inner wall of the receiving part, and the second end part is located on the top or sidewall of the receiving part.

[0029] In some preferred embodiments, the conductive path further comprises a third end part located on the receiving part; the third end part is electrically connected to the second end part and the first end part.

[0030] In some preferred embodiments, one to three grooves are provided on the receiving part; the grooves are located on the inner wall or bottom of the receiving part.

[0031] In some preferred embodiments, the fixing member further comprises a conductive sheet located on the receiving part; the conductive sheet is electrically connected to the end part of the conductive path.

[0032] The present application also provides a detection unit of an implantable analyte sensor, comprising an implantable analyte sensor and a fixing member of the implantable analyte sensor; the implantable analyte sensor comprises a front surface and a back surface, and has an electrode interface at the upper end of the front surface and the back surface respectively, and has an electrode area at the lower end of the front surface and the back surface respectively; the fixing member comprises a conductive path and a through hole.

[0033] In some preferred embodiments, the electrode area of the implantable analyte sensor is connected to the external device through the conductive channel.

[0034] In some preferred embodiments, the electrode interface on the reverse side of the implantable analyte sensor is connected to the external device through the conductive channel.

[0035] In some preferred embodiments, the fixing member further comprises a receiving part.

[0036] In some preferred embodiments, the conductive channel penetrates the receiving part.

[0037] In some preferred embodiments, the conductive path is distributed along the surface of the receiving part, the first end of the conductive path is located on the inner wall of the receiving part, and the second end of the conductive path is located on the top, side wall of the side, or side wall of the back of the fixing member.

[0038] In some preferred embodiments, the receiving part is provided with a groove for clamping and fixing the upper end of the implantable analyte sensor.

[0039] In some preferred embodiments, the fixing member is provided with a conductive channel for the conductive path to pass through.

[0040] In some preferred embodiments, a conductive sheet is further included, which is electrically connected to at least one end of the conductive channel.

[0041] In some preferred embodiments, the conductive sheet is located between the conductive channel and the electrode interface.

[0042] The fixing member can effectively reduce the difficulty of preparing a double-sided microelectrode sensor, and can effectively reduce the cost. In addition, the fixing member has a simple structure and a low manufacturing process, and the replacement of the sensor is simple and convenient. The implantable analyte sensor system with the fixing member has improved detection efficiency. The detection unit can distribute more electrodes in a limited area, and the fixing member for fixing the sensor has a small structure and a simple manufacturing process. BRIEF DESCRIPTION OF DRAWINGS

[0043] Figure 1 FIG. 1 is a schematic diagram of the structure of the sensor;

[0044] Figure 2-1 Figure 2-2 FIG. 2 is a schematic diagram of the structure of the sensor; Figure 2-3 FIG. 3 is a schematic diagram of the fixing member;

[0045] FIG. 3-1 is a schematic diagram of the front of the fixing member, wherein, Figure 3-1a is a schematic diagram of the conductive channel, Figure 3-1b is a schematic diagram of the conductive path, Figure 3-1c is a schematic diagram of the conductive sheet;​

[0046] Figure 3-2 is a schematic view of the back of the fixture, wherein, Figure 3-2a is a schematic view of the conductive channel, Figure 3-2b is a schematic view of the conductive path, Figure 3-2c is a schematic view of the conductive sheet;

[0047] Figure 3-3 Figure 3-3a and 3-3b are schematic views of the fixture after insertion of the sensor;

[0048] Figure 3-4 Figure 3-4a and 3-4b are schematic views of the layout of the conductive path through the housing of the fixture;

[0049] Figure 4-1 Figure 4-1a and 4-1b are schematic views of the conductive path on the outer surface of the housing;

[0050] Figure 4-2 Figure 4-2a , 4-2b and 4-2c are further schematic views of the conductive path on the outer surface of the housing;

[0051] Figure 4-3 Figure 4-3a and 4-3b are further schematic views of the fixture after insertion of the sensor;

[0052] Figure 4-4 Figure 4-4a , 4-4b and 4-4c are further schematic views of the conductive path on the outer surface of the housing;

[0053] Figure 5 is a schematic view of the conductive path partially through the housing and partially on the surface of the housing;

[0054] Figure 6 is a schematic view of an implantable analyte sensor system. DETAILED DESCRIPTION

[0055] The following examples further illustrate the present application. These examples are not meant to limit the scope of the present application, but to provide further understanding of the present application.

[0056] An implantable analyte sensor system (capable of continuously monitoring the concentration of an analyte in the blood of a human body, including but not limited to glucose, sodium ions and potassium ions), as shown in Figure 6 includes a detection unit, a signal transmission device, a data processing unit;

[0057] The detection unit and the signal transmission device are fixed in a shell which protects the internal electronic components, and a power supply (not shown in the drawings) is arranged in the shell to supply power to the electronic components in the shell.

[0058] The detection unit comprises an implantable analyte sensor 20, a fixing member 10 for fixing the implantable analyte sensor, and a sensor current data generating device. The sensor 20 in the present application refers to a sensor with double-sided microelectrodes.

[0059] Generally, as shown in Figure 1 The sensor 20 with double-sided microelectrodes comprises a front surface 22 and a back surface 23, and has electrode interfaces 21 (located in the interface area) at the upper end of the front surface and the back surface, respectively. The working electrode 25 and the counter electrode 24 are arranged at the lower end of the front surface 22, and the reference electrode 26 is arranged at the lower end of the back surface 23. The detection electrodes implanted into the human body, such as the working electrode 25, the counter electrode 24, and the reference electrode 26, are collectively referred to as the electrode area. The electrode area and the interface area are both indicated by a square in the figure.

[0060] As shown in FIG. 2- Figure 5 The fixing member 10 for the implantable analyte sensor in the present application comprises a support part 2, a receiving part 1, a conductive path 3, and a through hole 4. The receiving part 1 is composed of a receiving part top 14, a receiving part side wall 12, a receiving part bottom, and a receiving part inner wall 13. The support part 2 is connected to the bottom of the receiving part 1 and forms a receiving part bottom platform 11. The through hole 4 is located on the support part 2 and opens at one end of the receiving part bottom platform 11. The conductive path 3 is located on the receiving part 1. The conductive path 3 comprises at least two end parts.

[0061] The fixing member 10 is fixed on the base 30 of the shell, and the base 30 has a hole corresponding to the through hole 4 for the electrode area of the implantable analyte sensor 20 to pass through. The detection electrodes implanted into the human body, such as the working electrode 25, the counter electrode 24, and the reference electrode 26, are collectively referred to as the electrode area.

[0062] The electrode area of the implantable analyte sensor 20 is implanted under the skin of the human body through the through hole 4. The interface on the back surface of the implantable analyte sensor 20 is electrically connected to the sensor current data generating device through the conductive path 3 (other existing conductive materials can also be added between the conductive path and the sensor current data generating device for electrical connection). The interface on the front surface of the implantable analyte sensor 20 is electrically connected by using existing conductive materials, which include but are not limited to graphite, conductive adhesive tape, and copper wires.

[0063] The signal transmission device and the sensor current data generating device exchange data, and the two can exchange data through a data line or through wireless signals (such as Bluetooth, WiFi, radio frequency signals, and other existing wireless data exchange methods). To implement any data transmission method in the prior art, the signal transmission device needs to use the corresponding elements in the prior art.

[0064] The data processing unit and the signal transmission device exchange data, and the two can exchange data through a data line or through wireless signals.

[0065] The sensor current data generating device controls the implanted analyte sensor to detect the subcutaneous analyte through electrical signals, and receives the data generated by the implanted analyte sensor. The received data is transmitted to the data processing unit through the signal transmission device for processing and display. For example, a micro processing chip on the market can realize this function.

[0066] The data processing unit can be a smart terminal (smartphone, computer, tablet, etc.), or a component containing a display screen and a data processing chip, wherein the data processing chip is installed in the shell, and the display screen is installed on the shell.

[0067] The application provides a fixing member for an implanted analyte sensor, which is used for a sensor with double-sided microelectrodes (refer to Figure 1 ).

[0068] As Figures 2-1 to 2-3 , Figures 3-1 to 3-4, Figures 4-1 to 4-4, the cross section of the through hole 4 can be triangular, circular or semicircular, etc., for the sensor 20 implanting part (including the electrode area) to pass through, and the implanting part is inserted into the subcutaneous part of the human body after passing through the through hole 4. The number is 1. The through hole 4 is equidistant from the two side walls of the accommodating part 1, as Figures 2-1 to 2-2 ; it can also be biased to one side, as Figure 2-3 . Since the sensor 20 may not be enough to pierce the skin, it is necessary to combine with the puncture needle commonly used in the art, so that the detection electrode of the sensor 20 can be smoothly implanted into the subcutaneous part.

[0069] As shown in Figures 3-1 to 3-4, Figures 4-1 to 4-4 and Figure 5 , the conductive path 3 is used for electrical connection with the interface 21 of the reverse electrode of the sensor 20, as Figure 1 , and the conductive path 3 has at least two end portions, as Figure 4-2b, in addition to the first end 31, there is also a second end 32 and a third end 33. The number of conductive paths 3 is at least one, and can also be two or more, and the number is related to the number of reverse electrode interfaces of the sensor 20. If a temperature sensing electrode is added on the reverse side, the number of conductive paths needs to be increased by one. When the number of conductive paths is greater than one, the conductive paths 3 can be arranged along the same layout method, or they can be arranged in a variety of ways. The material of the conductive path 3 can be a conductive metal, a conductive polymer or other material with a conductive function (such as graphite), and its shape can be selectively linear, cylindrical, sheet-like, etc. The present invention takes a conductive path with two ends as an example, specifically a first end 31 and a second end 32. Among them, the first end 31 is located on one side of the fixing part 10, and is between the interface of the reverse electrode and the fixing part 10, and the second end 32 is located on the other side of the fixing part 10, and is connected to the interface corresponding to the sensor current data generating device.

[0070] The reverse electrode refers to the electrode facing the fixed part, e.g. Figure 1 Of course, if the working electrode 25 and the counter electrode 24 face the fixed member 10, the counter electrode can also refer to these two electrodes 24 and 25. The technical solution of the present invention is described by taking the reference electrode 26 as the counter electrode as an example.

[0071] refer to Figures 2-1 to 2-3 3-1, 3-4, 4-1, and 4-4, the accommodating portion 1 is composed of accommodating portion sidewalls 12, accommodating portion top 14, accommodating portion bottom, and accommodating portion inner wall 13. Together with the support portion, it forms the accommodating portion bottom platform 11 for accommodating the upper end electrode 21 of the sensor 20. In some embodiments, when a groove 5 is provided in the accommodating portion 1, the groove 5 is used to engage and secure the upper end of the sensor 20. See Figures 3-3 and 4-3.

[0072] The supporting portion 2 is used to support the accommodating portion 1 , and the through hole 4 also passes through the supporting portion 2 .

[0073] In the present invention, the fixing member 10 may further include a connecting portion (not shown in the figure), which is used to fix the fixing member 10 on the base 30 of the analyte detection device. The fixing method can be detachable (snap-in, screw-on, plug-in) or non-detachable (bonded with an adhesive and integrally formed with the base 30). Among them, the snap-in fixing method is the best. When in use, the sensor 20 can be directly inserted into the corresponding position of the fixing member 10 or pulled out. In this way, the sensor 20 can be quickly replaced, which not only reduces the replacement time but also simplifies the replacement steps.

[0074] The analyte detection device refers to a device that includes a detection unit, a signal transmission device and a power supply, and the device is fixed on the skin by bonding, bundling, etc.

[0075] In the present application, the fixing member can also include a sealing ring 8, such as the O-shaped rubber ring in FIG. 3-1, which can also be replaced by a hydrophobic film or other existing materials with sealing effect. The number of sealing rings is at least one, which is arranged around the support part 2, as shown in FIGS. 3-1 to 3-4 and FIGS. 4-1 to 4-4. The sealing ring 8 is used for waterproofing, specifically to prevent the fixed part of the human body from touching water (such as bathing, swimming, etc.) and water from seeping into the internal monitoring device, thereby affecting the internal electronic components.

[0076] The number of grooves 5 is 1 to 3, which is located on the side wall 12 of the accommodating part, or on the bottom platform 11 of the accommodating part, or a combination of both. The distribution of the arrangement of part of the grooves 5 can refer to Figures 2-1 to 2-3 . The groove 5 is used to position the interface area 27 of the sensor 20 and limit the movement of the interface area 27. The groove 5 located on the side wall also has the effect of guiding the insertion of the interface area 27. Among them, as Figures 2-1 to 2-3 , the width x of the groove 5 is greater than the edge thickness of the interface area 27, and the difference is greater than 0 mm and less than or equal to 0.5 mm, and further can be 0.05 to 0.2 mm, and preferably 0.1 mm, to prevent the difference from being too small to cause difficulty in insertion, and also to prevent the difference from being too large to reduce the effect of limiting the interface area. Similarly, the width y of the accommodating inner wall is greater than the length of the interface area, and the difference is greater than 0 mm and less than or equal to 0.5 mm, and further can be 0.05 to 0.2 mm, and preferably 0.1 mm, to prevent the difference from being too small to cause difficulty in insertion, and also to prevent the difference from being too large to reduce the effect of limiting the interface area. The value range of the above-mentioned accommodating inner wall width y is 2 to 5 mm.

[0077] As shown in FIG. 3-1-c, Figure 3-2c , Figure 3-3b , Figure 4-1b , Figure 4-2c , Figure 4-3b , Figure 4-4a The material used by the conductive sheet 6 can be a conductive metal, a conductive polymer, or other materials with conductive effect (such as graphite). The number of conductive sheets 6 can be one or more. The conductive sheet is electrically connected to one end or multiple ends of the conductive channel. When it is necessary to increase the connection strength, the conductive sheet 6 can be electrically connected to the first end 31 and / or the second end 32 by using a conductive adhesive material (conductive glue, conductive tape): when connected to the first end 31, it can make the first end 31 and the interface 21 of the opposite electrode conductive connection better; when connected to the second end 32, it can also make the second end 32 and the sensor current data generating device more stable and excellent in conductivity.

[0078] In the present application, the conductive channel 3 can pass through the accommodating part 1 of the fixing member, so that the two ports of the conductive channel 3 are respectively located on the inner wall 13 and the side wall 12 / top 14 of the accommodating part 1, that is, one port is located on the inner wall 13 of the accommodating cavity, and the other port is located on the side wall 12 or the top 14. At this time, the fixing member is provided with a conductive hole 7, such as Figures 2-1 to 2-3 , FIGS. 3-1 to 3-2, the conductive hole 7 Figure 3-1a and Figure 3-2a ) is used for the conductive channel 3 to pass through, so that the first end 31 of the conductive channel 3 points to the inner wall 13 of the accommodating part of the fixing member 10, such as Figure 3-1b , and the second end 32 of the conductive channel 3 is located on the other surface of the accommodating part 1, such as Figure 3-2b , the second end 32 in , the back side wall 12 of the fixing member accommodating part 1, but this does not mean that the second end 32 must be located on this surface, and can also be a side surface in addition thereto, for example, FIG. 3-4.

[0079] Figure 3-1b In one embodiment, the first end 31 points to the inner wall 13 of the accommodating part, and it can be electrically connected with the interface 21 of the back electrode of the sensor 20, as shown in

[0080] In one embodiment, the first end 31 is provided with a conductive sheet 6 between the back electrode of the sensor 20, the interface 21 of the back electrode is electrically connected with the conductive sheet 6, the first end 31 is electrically connected with the conductive sheet 6, and the conductive sheet 6 is located on the surface of the inner wall 13 of the accommodating part, as shown in Figure 3-1c .

[0081] In one embodiment, the second end 32 is located on the back side wall 12 of the fixing member 10, so that it can be electrically connected with the interface of the sensor current data generating device, as shown in Figure 3-2b .

[0082] In one embodiment, the back side wall 12 of the fixing member 10 is provided with a conductive sheet 6, the second end 32 is electrically connected with the conductive sheet 6, and the conductive sheet 6 can also be electrically connected with the interface of the sensor current data generating device, and the connection strength of the electrical signal is enhanced, as shown in Figure 3-2c .

[0083] In one embodiment, the conductive hole 7 is a curve or a broken line, the first end 31 of the conductive channel 3 points to the inner wall 13 of the accommodating part, and the second end 32 points to the side wall 12 or the top 14 of the fixing member, as shown in Figure 3-4a and Figure 3-4b .

[0084] In a preferred embodiment, the first end 31 is provided with a conductive sheet 6 between the counter electrode 21 of the sensor 20, and the back of the fixing member is also provided with a conductive sheet 6, the second end 32 is electrically connected with the conductive sheet 6, and the effect after the sensor 20 is inserted into the fixing member 10 is as shown in Figure 3-3a and Figure 3-3b .

[0085] In the present application, the conductive channel 3 can be located on the outer surface of the accommodating portion 1 of the fixing member, and the two ports of the conductive channel 3 are respectively located on the inner wall 13 and the side wall 12 / top 14 of the accommodating portion 1, that is, one port is located on the inner wall 13 of the accommodating cavity, and the other port is located on the side wall 12 or the top 14. At this time, the accommodating portion 1 is not provided with a conductive hole 7, and the conductive channel 3 is distributed along the surface of the accommodating portion 1, so that the first end 31 of the conductive channel 3 is located on the inner wall 13 of the accommodating portion (as shown in FIG. 4-1, FIG. 4-4, Figure 4-3a . Figure 4-2a Figure 4-4a Figure 4-4c Figure 4-2b Figure 4-2c Figure 4-3b Figure 4-4b In order to increase the adhesion strength of the conductive channel 3 on the surface of the fixing member 10, a layer of adhesion layer or adhesive can be provided between the conductive channel 3 and the surface of the fixing member 10, in addition to which, the fixing can also be carried out in the inlaying manner.

[0086] In the present application, the conductive channel 3 can partially penetrate the accommodating portion 1, and the other part is located on the outer surface of the accommodating portion 1 of the fixing member, and the two ports of the conductive channel 3 are respectively located on the inner wall and the side wall / top of the accommodating portion 1. For example Figure 5 as shown, the conductive channel 3 can penetrate a part (black dashed line part) through the fixing member, and the other part (black solid line part) extends along the surface of the accommodating portion 1 to the side wall 12 of the back of the accommodating portion 1, which can also be the top 14 or the side wall 12 of the side, and vice versa.​​​​​​

Claims

1. A detection unit for an implantable analyte sensor, comprising an implantable analyte sensor and a fixing member for the implantable analyte sensor, characterized in that: The implantable analyte sensor comprises a front side and a back side, each having an electrode interface at the upper end of the front side and the back side, and an electrode area at the lower end of the front side and the back side; the fixing member comprises a supporting portion, a receiving portion, a conductive path, and a through hole; The accommodating portion is composed of a top portion, side walls, a bottom portion and an inner wall of the accommodating portion, and the supporting portion is connected to the bottom portion of the accommodating portion to form a bottom platform of the accommodating portion; the through hole is located on the supporting portion, and one end is open to the bottom platform of the accommodating portion; the conductive path is located on the accommodating portion; the conductive path includes a first end and a second end, and both the first end and the second end can be electrically connected to the interface of the sensor current data generating device.

2. The detection unit of the implantable analyte sensor according to claim 1, characterized in that The electrode area of ​​the implantable analyte sensor passes through the through-hole.

3. The detection unit of the implantable analyte sensor according to claim 1, characterized in that The electrode interface on the back side of the implantable analyte sensor is electrically connected to an external device through a conductive path.

4. The detection unit of the implantable analyte sensor according to claim 1, characterized in that The conductive path further includes a third end portion located on the accommodating portion; the third end portion is electrically connected to the second end portion and the first end portion.

5. The detection unit of the implantable analyte sensor according to claim 1, characterized in that The conductive path passes through the receiving portion.

6. The detection unit of the implantable analyte sensor according to claim 1, characterized in that The conductive path is distributed along the surface of the accommodating portion, the first end of the conductive path is located on the inner wall of the accommodating portion, and the second end of the conductive path is located on the top, side wall or back side wall of the fixing member.

7. The detection unit of the implantable analyte sensor according to claim 1, characterized in that: A groove for locking and fixing the upper end portion of the implantable analyte sensor is provided in the accommodating portion.

8. The detection unit of the implantable analyte sensor according to claim 1, characterized in that The fixing piece is provided with a conductive hole, and the conductive hole is used for a conductive path to pass through.

9. The detection unit of the implantable analyte sensor according to claim 1, characterized in that: The device further includes a conductive sheet electrically connected to at least one end of the conductive path.

10. The detection unit of the implantable analyte sensor according to claim 9, characterized in that: The conductive sheet is located between the conductive path and the electrode interface.

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