Drip dyeing equipment and drip dyeing method capable of improving speed and effect
Through the combined technology of constant temperature preheating and ultrasonic resonance, the problem of inconsistent dyeing effects of the drip dyeing machine at different temperatures is solved, stable dyeing speed and quality are achieved, and reagent overflow and interference with operating accuracy are avoided.
Patent Information
- Application Number
- CN202210558176.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-05-21
- Publication Date
- 2025-09-16
- Estimated Expiration
- 2042-05-21
AI Technical Summary
The existing drip dyeing machines have inconsistent dyeing effects under different temperature environments, and the mechanical vibration mode easily causes reagent overflow and interferes with operating accuracy.
It adopts a constant temperature preheating mechanism and an ultrasonic resonance mechanism, uses a heating wire and a heat conducting rod to heat the reagent in a water bath or oil bath, and uses a specific frequency sound wave in combination with an ultrasonic resonance head to pass through the reagent on the glass slide, thereby achieving constant temperature preheating and high-frequency vibration of the reagent and improving the penetration effect.
The stability of dyeing speed and effect is achieved, the influence of temperature environment, reagent overflow and operation accuracy interference are avoided, and the dyeing quality is improved.
Smart Images

Figure CN114791381B_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of pathological detection, and in particular relates to a dripping device and a dripping method capable of improving speed and effect. Background Art
[0002] During operation, existing drip dyeing machines drip reagents onto a stained tissue-attached slide, wait for the reagents to fully react with the tissue, then suck out the waste liquid, drip in the next reagent, and repeat the above process. The more fully the reagent penetrates the tissue, the faster the dyeing speed and the better the dyeing effect. The reaction speed and effect of the reagents and tissues are affected by the temperature. In different seasons, under the same other conditions, the dyeing effect will be inconsistent.
[0003] Existing drip dyeing machines use mechanical vibration to accelerate the penetration of reagents into tissues. This operation method easily causes the reagents to overflow and interferes with the operating accuracy of the drip dyeing machine.
[0004] Therefore, we propose a drip dyeing device and a drip dyeing method that can improve speed and effect to solve the above problems. Summary of the Invention
[0005] The object of the present invention is to provide a drip dyeing device and a drip dyeing method that can improve speed and effect in view of the above problems.
[0006] To achieve the above-mentioned object, the present invention provides the following technical solution: a drip dyeing device capable of improving speed and effect, comprising a base, the upper end of which is fixedly connected to a constant temperature preheating mechanism and an ultrasonic resonance mechanism;
[0007] The constant temperature preheating mechanism includes a preheating box, a plurality of reagent transfer bottles are placed in the preheating box, a temperature measuring probe is fixedly arranged in the preheating box, a plurality of heat-conducting rods are fixedly inserted into the bottom side wall of the preheating box, a heating wire is arranged in the heat-conducting rod, heating boxes are clamped on the opposite sides of the preheating box, a plurality of U-shaped elastic clamps are evenly fixedly connected in the heating box, a slide is inserted in the U-shaped elastic clamp, a heat-conducting cavity corresponding to the position of the heating box is opened on the inner side of the preheating box, a first heat-conducting plate is fixedly embedded in the inner side wall of the corresponding heat-conducting cavity of the preheating box, a second heat-conducting plate is fixedly embedded in the outer side wall of the corresponding heat-conducting cavity of the preheating box, and the heat-conducting cavity is relatively close to each other. One side inner wall is rotatably connected to a heat insulating roller through a rotating shaft, and a torsion spring sleeved on the outside of the rotating shaft is fixedly connected between the upper and lower inner walls of the heat conducting cavity and the heat insulating roller, and a heat transfer block is fixedly embedded in the middle of the heat insulating roller, and the lower end of the outer side of the preheating box is evenly fixedly connected to a plurality of telescopic rods supported on the lower side of the heating box, and the end of the telescopic rod away from the preheating box is fixedly connected to a side baffle connected to the outside of the heating box, and the side wall of the preheating box is provided with a transmission cavity located on the lower side of the heat conducting cavity, one end of the rotating shaft extends through the transmission cavity and is fixedly sleeved with a pulley, a pulling rope is wound around the outside of the pulley, and one end of the pulling rope passes through the telescopic tube and is fixedly connected to the outside of the side baffle.
[0008] In the above-mentioned drip dyeing equipment that can improve speed and effect, the ultrasonic resonance mechanism includes a resonance support platform fixedly connected to the upper end of the base and an L-shaped support plate located on one side of the resonance support platform, the upper end of the L-shaped support plate is fixedly connected to a fixed seat, and a plurality of ultrasonic resonance heads are fixedly inserted on the fixed seat, and the ultrasonic resonance heads are arranged directly above the resonance support platform, and a plurality of connecting seats are evenly fixedly connected to the resonance support platform, and two elastic pressure plates are fixedly connected to one side of the upper end of the connecting seat, and a plurality of dividing blocks are also evenly fixedly connected to the resonance support platform, and a plurality of metal glass slides pressed on the lower side of the elastic pressure plate are installed on the resonance support platform, and a heating base is fixedly installed on the lower side of the resonance support platform, and a plurality of heating rods and temperature sensors corresponding to the positions of the heating rods are installed in the heating base, and a waste liquid discharge hole is also opened on one side of the bottom of the heating base.
[0009] In the above-mentioned drip dyeing equipment that can improve speed and effect, the two opposite sides of the heating box are integrally connected with limit plates, and the outer side of the preheating box is symmetrically fixedly connected with two L-shaped clamping plates clamped with the limit plates.
[0010] In the above-mentioned drip dyeing device capable of improving speed and effect, the first heat conducting plate, the second heat conducting plate and the heat transfer block are all made of copper alloy.
[0011] In the above-mentioned drip dyeing equipment capable of improving speed and effect, the heat conduction cavity corresponding to the preheating box is filled with heat-insulating argon gas.
[0012] In the above-mentioned drip dyeing device capable of improving speed and effect, the ultrasonic resonance head is specifically a variable frequency ultrasonic generator.
[0013] A drip dyeing method capable of improving speed and effect comprises the following steps:
[0014] S1. The reagents involved in the reaction are loaded into reagent transfer bottles, and multiple reagent transfer bottles are placed in a preheating box. Water or oil is added to the preheating box, and the heating wire is energized to heat the heating wire. Heat is transferred to the preheating box through the heat conducting rod. The reagents involved in the reaction are then preheated in a water bath or oil bath and maintained at a constant temperature. The preheating temperature in the preheating box is monitored in real time by a temperature probe, and the preheating temperature is adjusted according to the required temperature.
[0015] S2. Multiple slides are clamped on the U-shaped elastic clamping plate in the heating box to relatively fix the slides, and then the heating box and the preheating box are accurately clamped by the relative clamping of the L-shaped clamping plate and the limit plate. At this time, the lower end of the heating box is supported on the upper end of the telescopic rod, and the side baffle is blocked on the outside of the heating box to limit the heating box. When the heating box is clamped, the telescopic rod is synchronously pulled outward, and then the pulley is driven to rotate by the pulling rope, and then the rotating shaft is driven to rotate. The rotating shaft drives the heat-insulating roller to rotate synchronously by 90 degrees, so that the heat transfer block on the heat-insulating roller is connected between the first heat-conducting plate and the second heat-conducting plate, so that the heat in the preheating box can be transferred to the outside of the preheating box through the heat-conducting cavity, and the slides in the heating box are synchronously preheated;
[0016] S3. Place the preheated glass slide on the metal glass slide plate on the resonance support, and use the elastic pressure plate connected to the side wall of the seat to stably press and fix one end of the glass slide. Then, drop the preheated reagent in the reagent transfer bottle onto the glass slide with tissue attached, so that it can fully react with the tissue, and simultaneously start the ultrasonic resonance head. Adjust the sound wave frequency of the ultrasonic resonance head according to the resonance frequency of the test kit slide. Use sound waves of a specific frequency to pass through the reagent on the glass slide, driving the reagent on the glass slide and the tissue to generate high-frequency vibrations, thereby improving the penetration effect of the reagent into the tissue and accelerating the staining reaction. At the same time, start the heating rod in the heating base, and accurately control the heating temperature through the temperature sensor, so that the glass slide can be heated in real time, further improving the penetration effect.
[0017] Compared with the prior art, the present invention provides a drip dyeing device and a drip dyeing method that can improve speed and effect, and has the following beneficial effects:
[0018] 1. The drip dyeing equipment and method that can improve speed and effect are equipped with a preheating box. The preheating box uses a heating wire and a heat conducting rod to perform water bath or oil bath heating to preheat the reagent in the reagent transfer bottle at a constant temperature. As the temperature of the reagent is increased, the molecular movement is accelerated, which can effectively increase the dyeing speed. Moreover, since the temperature of the reagent is kept constant, the influence of the temperature environment on the dyeing effect can be avoided, the consistency of the dyeing effect is achieved, and the dyeing quality is improved.
[0019] 2. The drip dyeing equipment and method can improve the speed and effect. A glass slide is placed on the resonance support through a resonant support. The ultrasonic resonance head uses sound waves of a specific frequency to pass through the reagent on the glass slide, driving the reagent on the glass slide and the tissue to vibrate at high frequency, thereby improving the penetration effect of the reagent into the tissue and accelerating the dyeing reaction speed.
[0020] 3. The drip dyeing equipment and method can improve the speed and effect. Through the heating box provided, the glass slide is placed in the heating box, and the heating box is placed on the outside of the preheating box. When the heating box is placed, the side baffle and the telescopic rod are simultaneously driven to move outward, thereby driving the heat insulation roller to rotate, so that the heat transfer block contacts the first heat conduction plate and the second heat conduction plate, so that the heat in the preheating box is transferred to the outside, and the glass slide is preheated synchronously. When the glass slide does not need to be preheated, the heat insulation roller is reset and rotated, so that the heat transfer block is separated from the heat conduction connection with the first heat conduction plate and the second heat conduction plate, thereby avoiding the problem of continuous heat transfer from the outer wall of the preheating box, which may cause burns to people and waste of heat energy, and saving energy and being environmentally friendly.
[0021] In summary, the present invention effectively improves the dyeing speed and effect, avoids the problem of inconsistent dyeing effects affected by the temperature environment, and ensures the operating accuracy of the drip dyeing machine without using mechanical vibration. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 This is a schematic structural diagram of a drip dyeing device proposed by the present invention that can improve speed and effect;
[0023] Figure 2 This is a partial three-dimensional structural diagram of a preheating box for a drip dyeing device proposed by the present invention that can improve speed and effect;
[0024] Figure 3 This is a schematic diagram of a partial top view of a preheating box for a drip dyeing device proposed by the present invention that can improve speed and effect;
[0025] Figure 4 This is a schematic diagram of a top view and cross-section of the connection between the preheating box and the heating box of a drip dyeing device proposed by the present invention, which can improve the speed and effect;
[0026] Figure 5This is a schematic diagram of a partial front cross-sectional structure of a side wall of a preheating box of a drip dyeing device proposed by the present invention, which can improve speed and effect;
[0027] Figure 6 This is a schematic diagram of the three-dimensional structure of a resonance support platform for a drip dyeing device that can improve speed and effect, as proposed by the present invention;
[0028] Figure 7 This is a schematic diagram of the three-dimensional structure of the connection between the resonance support platform and the heating base plate of a drip dyeing equipment proposed by the present invention, which can improve the speed and effect.
[0029] In the figure: 1. Base; 2. Preheating box; 3. Reagent transfer bottle; 4. Temperature measuring probe; 5. Thermal rod; 6. Heating wire; 7. Heating box; 8. U-shaped elastic clamping plate; 9. Glass slide; 10. Thermal chamber; 11. First thermal plate; 12. Second thermal plate; 13. Rotating shaft; 14. Insulating roller; 15. Torsion spring; 16. Heat transfer block; 17. Telescopic rod; 18. Side baffle; 19. Transmission chamber; 20. Pulley; 21. Pull rope; 22. Resonance support platform; 23. L-shaped support plate; 24. Fixed seat; 25. Ultrasonic resonance head; 26. Connecting seat; 27. Elastic pressure plate; 28. Separator; 29. Limiting plate; 30. L-shaped clamping plate; 31. Metal glass plate; 32. Heating base; 33. Heating rod; 34. Temperature sensor; 35. Waste liquid discharge hole. DETAILED DESCRIPTION
[0030] The following examples are for illustrative purposes only and are not intended to limit the scope of the present invention.
[0031] See also Figure 1-7 , a drip dyeing device capable of improving speed and effect, comprising a base 1, the upper end of which is fixedly connected with a constant temperature preheating mechanism and an ultrasonic resonance mechanism;
[0032] The constant temperature preheating mechanism includes a preheating box 2, in which a plurality of reagent transfer bottles 3 are placed, a temperature measuring probe 4 is also fixedly provided in the preheating box 2, a plurality of heat conducting rods 5 are fixedly inserted into the bottom side wall of the preheating box 2, a heating wire 6 is provided in the heat conducting rod 5, heating boxes 7 are clamped on the opposite sides of the preheating box 2, and the opposite sides of the heating box 7 are integrally connected to the limiting plate 29, the outer side of the preheating box 2 is symmetrically fixedly connected to two L-shaped clamping plates 30 clamped with the limiting plate 29, a plurality of U-shaped elastic clamping plates 8 are evenly fixedly connected in the heating box 7, a slide 9 is inserted in the U-shaped elastic clamping plate 8, a heat conducting cavity 10 corresponding to the position of the heating box 7 is opened on the inner side of the preheating box 2, the corresponding heat conducting cavity 10 of the preheating box 2 is filled with heat insulating argon gas, the inner side wall of the corresponding heat conducting cavity 10 of the preheating box 2 is fixedly embedded with a first heat conducting plate 11, and the outer side wall of the corresponding heat conducting cavity 10 of the preheating box 2 is fixedly embedded with a second heat conducting plate 1 2. The inner wall of the upper and lower opposite sides of the heat conduction chamber 10 is rotatably connected to the heat insulation roller 14 through the rotating shaft 13. The upper and lower inner walls of the heat conduction chamber 10 and the heat insulation roller 14 are fixedly connected with a torsion spring 15 sleeved outside the rotating shaft 13. A heat transfer block 16 is fixedly embedded in the middle of the heat insulation roller 14. The first heat conduction plate 11, the second heat conduction plate 12 and the heat transfer block 16 are all made of copper alloy. The lower end of the outer side of the preheating box 2 is evenly fixedly connected with a plurality of supports mounted on The telescopic rod 17 on the lower side of the heating box 7 is fixedly connected to the side baffle 18 on the outside of the heating box 7 at one end of the telescopic rod 17 away from the preheating box 2. The side wall of the preheating box 2 is provided with a transmission cavity 19 located on the lower side of the heat conduction cavity 10. One end of the rotating shaft 13 extends into the transmission cavity 19 and is fixedly sleeved with a pulley 20. A pulling rope 21 is wound around the outside of the pulley 20. One end of the pulling rope 21 passes through the telescopic tube and is fixedly connected to the outside of the side baffle 18.
[0033] The ultrasonic resonance mechanism includes a resonance support 22 fixedly connected to the upper end of the base 1 and an L-shaped support plate 23 located on one side of the resonance support 22. The upper end of the L-shaped support plate 23 is fixedly connected to a fixed seat 24, and a plurality of ultrasonic resonance heads 25 are fixedly inserted on the fixed seat 24. The ultrasonic resonance head 25 is specifically a variable frequency ultrasonic generator. The ultrasonic resonance head 25 is arranged directly above the resonance support 22. A plurality of connecting seats 26 are evenly fixedly connected to the resonance support 22. Two elastic pressure plates 27 are fixedly connected to one side of the upper end of the connecting seat 26. A plurality of dividing blocks 28 are also evenly fixedly connected to the resonance support 22. A plurality of metal glass disks 31 are installed on the resonance support 22 and are pressed onto the lower side of the elastic pressure plate 27. A heating base 32 is fixedly provided on the lower side of the resonance support 22. A plurality of heating rods 33 and temperature sensors 34 corresponding to the positions of the heating rods 33 are installed in the heating base 32. A waste liquid discharge hole 35 is also provided on one side of the bottom of the heating base 32.
[0034] A drip dyeing method capable of improving speed and effect comprises the following steps:
[0035] S1. The reagents involved in the reaction are loaded into a reagent transfer bottle 3, and then multiple reagent transfer bottles 3 are placed in a preheating box 2. Water or oil is added to the preheating box 2. The heating wire 6 is energized to heat the heating wire 6, and heat is transferred to the preheating box 2 through the heat conducting rod 5. The reagents involved in the reaction are then preheated in a water bath or oil bath and maintained at a constant temperature. The temperature measuring probe 4 monitors the preheating temperature in the preheating box 2 in real time and adjusts the preheating temperature as needed.
[0036] S2. Multiple glass slides 9 are clamped on the U-shaped elastic clamping plate 8 in the heating box 7 to relatively fix the glass slides 9, and then the heating box 7 and the preheating box 2 are accurately clamped by the relative clamping of the L-shaped clamping plate 30 and the limiting plate 29. At this time, the lower end of the heating box 7 is supported on the upper end of the telescopic rod 17, and the side baffle 18 is blocked on the outside of the heating box 7 to limit the heating box 7. When the heating box 7 is clamped, the telescopic rod 17 is synchronously pulled outward, and then the pulley 20 is driven to rotate by the pulling rope 21, and then the rotating shaft 13 is driven to rotate. The rotating shaft 13 drives the heat-insulating roller 14 to rotate synchronously by 90 degrees, so that the heat transfer block 16 on the heat-insulating roller 14 is connected between the first heat-conducting plate 11 and the second heat-conducting plate 12, so that the heat in the preheating box 2 can be transferred to the outside of the preheating box 2 through the heat-conducting cavity 10, and the glass slides 9 in the heating box 7 are synchronously preheated.
[0037] S3. Place the preheated glass slide 9 on the metal glass slide plate 31 on the resonance support 22, and the elastic pressure plate 27 on the side wall of the connecting seat 26 stably presses and fixes one end of the glass slide 9, and then drip the preheated reagent in the reagent transfer bottle 3 onto the glass slide 9 with tissue attached, so that it can actually react fully with the tissue, and synchronously start the ultrasonic resonance head 25, adjust the sound wave frequency of the ultrasonic resonance head 25 according to the resonance frequency of the test reagent slide 9, use the sound wave of a specific frequency to pass through the reagent on the glass slide 9, drive the reagent on the glass slide 9 and the tissue to generate high-frequency vibration, improve the penetration effect of the reagent on the tissue, speed up the staining reaction, and at the same time start the heating rod 33 in the heating base 32, and accurately control the heating temperature through the temperature sensor 34, so that the glass slide 9 can be heated in real time, further improving the penetration effect.
[0038] The operating principle of the present invention is described as follows: the reagents involved in the reaction are loaded into the reagent transfer bottle 3, and then multiple reagent transfer bottles 3 are placed in the preheating box 2. Water or oil is added to the preheating box 2, and the electric heating wire is energized to heat the heating wire 6, and heat is transferred to the preheating box 2 through the heat conducting rod 5. Then, the reagents involved in the reaction are preheated in a water bath or oil bath and maintained at a constant temperature. The temperature measuring probe 4 monitors the preheating temperature in the preheating box 2 in real time, thereby According to the required preheating temperature, multiple slides 9 are clamped on the U-shaped elastic clamping plate 8 in the heating box 7 to relatively fix the slides 9, and then the heating box 7 and the preheating box 2 are accurately clamped by the relative clamping of the L-shaped clamping plate 30 and the limiting plate 29. At this time, the lower end of the heating box 7 is supported on the upper end of the telescopic rod 17, and the side baffle 18 is connected to the outside of the heating box 7 to limit the heating box 7. When the heating box 7 is clamped, the telescopic rod 17 is pulled outward synchronously, and then the pulling rope 2 is used to pull the heating box 7. 1 drives the pulley 20 to rotate, thereby driving the rotating shaft 13 to rotate. The rotating shaft 13 drives the heat-insulating roller 14 to rotate synchronously by 90 degrees, so that the heat transfer block 16 on the heat-insulating roller 14 is connected between the first heat conducting plate 11 and the second heat conducting plate 12. The heat in the preheating box 2 is transferred to the outside of the preheating box 2 through the heat conducting cavity 10, and the glass slide 9 in the heating box 7 is synchronously preheated. The preheated glass slide 9 is placed on the resonance support 22. The elastic pressure plate 27 on the side wall of the connecting seat 26 stably presses and fixes one end of the glass slide 9. Then, the preheated reagent in the reagent transfer bottle 3 is dripped onto the glass slide 9 with tissue attached, so that it can fully react with the tissue. At the same time, the ultrasonic resonance head 25 is started, and the sound wave frequency of the ultrasonic resonance head 25 is adjusted according to the resonant frequency of the test reagent slide 9. The sound wave of the ultrasonic resonance head 25 is used to pass through the reagent on the glass slide 9, driving the reagent on the glass slide 9 and the tissue to generate high-frequency vibration, thereby improving the penetration effect of the reagent into the tissue and accelerating the staining reaction speed.
[0039] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.
Claims
1. A drip dyeing device capable of improving speed and effect, comprising a base (1), characterized in that: The upper end of the base (1) is fixedly connected with a constant temperature preheating mechanism and an ultrasonic resonance mechanism; The constant temperature preheating mechanism comprises a preheating box (2), a plurality of reagent transfer bottles (3) are placed in the preheating box (2), a temperature measuring probe (4) is fixedly arranged in the preheating box (2), a plurality of heat conducting rods (5) are fixedly inserted into the bottom side wall of the preheating box (2), a heating wire (6) is arranged in the heat conducting rod (5), heating boxes (7) are clamped on opposite sides of the preheating box (2), and a plurality of U-shaped elastic springs are evenly fixedly connected in the heating box (7). A card board (8) is inserted into the U-shaped elastic card board (8) and a glass slide (9) is installed. A heat conduction cavity (10) corresponding to the position of the heating box (7) is opened on the inner side of the preheating box (2). A first heat conduction plate (11) is fixedly embedded in the inner side wall of the preheating box (2) corresponding to the heat conduction cavity (10). A second heat conduction plate (12) is fixedly embedded in the outer side wall of the preheating box (2) corresponding to the heat conduction cavity (10). The inner walls of the upper and lower opposite sides of the heat conduction cavity (10) are rotated. The shaft (13) is rotatably connected to a heat-insulating roller (14), and a torsion spring (15) sleeved on the outside of the shaft (13) is fixedly connected between the upper and lower inner walls of the heat-conducting cavity (10) and the heat-insulating roller (14). A heat transfer block (16) is fixedly embedded in the middle of the heat-insulating roller (14). The lower end of the outer side of the preheating box (2) is evenly fixedly connected to a plurality of telescopic rods (17) supported on the lower side of the heating box (7), and the telescopic rods (17) are away from the preheating box (2). ) is fixedly connected to a side baffle (18) connected to the outside of the heating box (7), and a transmission cavity (19) is provided on the side wall of the preheating box (2) and is located on the lower side of the heat conduction cavity (10). One end of the rotating shaft (13) extends through the transmission cavity (19) and is fixedly sleeved with a pulley (20). A pulling rope (21) is wound around the outside of the pulley (20), and one end of the pulling rope (21) passes through the telescopic tube and is fixedly connected to the outside of the side baffle (18).
2. The drip dyeing device capable of improving speed and effect according to claim 1, characterized in that: The ultrasonic resonance mechanism comprises a resonance support platform (22) fixedly connected to the upper end of the base (1) and an L-shaped support plate (23) located on one side of the resonance support platform (22), the upper end of the L-shaped support plate (23) is fixedly connected to a fixing seat (24), a plurality of ultrasonic resonance heads (25) are fixedly inserted on the fixing seat (24), and the ultrasonic resonance heads (25) are arranged directly above the resonance support platform (22), a plurality of connecting seats (26) are evenly fixedly connected to the resonance support platform (22), and one side of the upper end of the connecting seat (26) is fixedly connected There are two elastic pressure plates (27), and a plurality of partition blocks (28) are evenly fixedly connected to the resonance support (22). A plurality of metal glass plates (31) are installed on the resonance support (22) and are pressed against the lower side of the elastic pressure plates (27). A heating base (32) is fixedly provided on the lower side of the resonance support (22). A plurality of heating rods (33) and temperature sensors (34) corresponding to the positions of the heating rods (33) are installed in the heating base (32). A waste liquid discharge hole (35) is also opened on one side of the bottom of the heating base (32).
3. The drip dyeing device capable of improving speed and effect according to claim 1, characterized in that: The heating box (7) has two opposite sides integrally connected to the limiting plates (29), and the outer side of the preheating box (2) is symmetrically fixedly connected to two L-shaped clamping plates (30) that are clamped to the limiting plates (29).
4. The drip dyeing device capable of improving speed and effect according to claim 1, characterized in that: The first heat conducting plate (11), the second heat conducting plate (12) and the heat transfer block (16) are all made of copper alloy.
5. The drip dyeing device capable of improving speed and effect according to claim 1, characterized in that: The heat conduction cavity (10) corresponding to the preheating box (2) is filled with heat-insulating argon gas.
6. The drip dyeing device capable of improving speed and effect according to claim 2, characterized in that: The ultrasonic resonance head (25) is specifically a variable frequency ultrasonic generator.
7. A drip dyeing method capable of improving speed and effect based on any one of claims 1 to 6, characterized in that: The steps include: S1. The reagents involved in the reaction are placed in a reagent transfer bottle (3), and then a plurality of reagent transfer bottles (3) are placed in a preheating box (2). Water or oil is added to the preheating box (2), and the electric heating wire is energized so that the heating wire (6) is energized and heated, and heat is transferred to the preheating box (2) through the heat conducting rod (5), and then the reagents involved in the reaction are preheated in a water bath or an oil bath and maintained at a constant temperature. The temperature measuring probe (4) monitors the preheating temperature in the preheating box (2) in real time, and adjusts the preheating temperature according to the required temperature. S2. A plurality of slides (9) are clamped on the U-shaped elastic clamping plate (8) in the heating box (7) to relatively fix the slides (9), and then the heating box (7) and the preheating box (2) are accurately clamped by the relative clamping of the L-shaped clamping plate (30) and the limiting plate (29). At this time, the lower end of the heating box (7) is supported on the upper end of the telescopic rod (17), and the side baffle (18) is blocked on the outside of the heating box (7) to limit the position of the heating box (7). When the heating box (7) is clamped, the telescopic rod (17) The heat transfer block (16) on the heat-insulating roller (14) is connected between the first heat-conducting plate (11) and the second heat-conducting plate (12), thereby enabling the heat in the preheating box (2) to be transferred to the outside of the preheating box (2) through the heat-conducting cavity (10), and performing a synchronous preheating operation on the glass slide (9) in the heating box (7); S3. Place the preheated glass slide (9) on the metal glass slide plate (31) on the resonance support (22), and use the elastic pressure plate (27) on the side wall of the connecting seat (26) to stably press and fix one end of the glass slide (9). Then, drip the preheated reagent in the reagent transfer bottle (3) onto the glass slide (9) with tissue attached, so that it can fully react with the tissue, and simultaneously start the ultrasonic resonance head (25). Adjust the sound wave frequency of the ultrasonic resonance head (25) according to the resonance frequency of the reagent slide (9). Use the sound wave of a specific frequency to pass through the reagent on the glass slide (9), drive the reagent on the glass slide (9) and the tissue to generate high-frequency vibration, thereby improving the penetration effect of the reagent on the tissue and accelerating the staining reaction speed. At the same time, start the heating rod (33) in the heating base (32), and accurately control the heating temperature through the temperature sensor (34). The glass slide (9) can be heated in real time, further improving the penetration effect.
Citation Information
Patent Citations
Drop dyeing equipment capable of improving speed and effect
CN217931039U