A flip displacement fully sealed thermal cover system and driving method

Abstract

The present invention relates to a flip displacement fully sealed hot cover system and a driving method, comprising a hot cover and a displacement driving module which are not fixedly connected to each other. The hot cover inside a cartridge is driven by a separate external displacement driving module to perform a required single-degree-of-freedom flip displacement, so as to achieve the required hot cover displacement activity and ensure that sufficient effective operating space is provided above a PCR tube for operation of other functional components such as a pipette after the hot cover is opened. The hot cover which is separately arranged in the cartridge can simply use an elastic sealing material to ensure the sealing of the cartridge during the displacement process, and is simple to manufacture and low in cost. In particular, the hot cover is small in size and is suitable for use in instruments with limited internal space. The hot cover is an ideal solution for heating the hot cover in the library preparation process.

Description

Technical Field

[0001] The present invention relates to the technical field of gene detection, and in particular to a flip-displacement fully sealed thermal cover system and a driving method. Background Art

[0002] During the library preparation PCR process, in order to prevent the water in the main reaction well sample from evaporating and condensing on the PCR tube cover, it is usually necessary to heat the PCR tube cover. Compared with the method of adding paraffin oil to prevent evaporation, using a hot cover for heating avoids the problem of difficult removal of paraffin oil after the reaction is completed, and has become a commonly used solution.

[0003] Most of the hot covers used in the prior art come from the thermal cycler structure, corresponding to the fixed structure of the 96-well plate or PCR strip tube. When heating is required, the motor drives the active structure to compress the PCR tube cover and use the hot cover (such as PI heating film) to heat the PCR tube cover. The hot cover structure used in the prior art can well realize the heating of the PCR tube cover, but it cannot be directly applied in the library preparation process. Compared with the simple PCR thermal cycle process, the library preparation process is more complicated. In addition to heating, it is also necessary to use components such as pipettes for operations such as sample addition and pipetting. It is obviously necessary to control the opening and closing of the hot cover according to the operating steps and provide available operating space for other functional components (such as pipettes), and the heating effect of the hot cover cannot be considered alone; on the other hand, in order to ensure the reliability of the prepared library, the entire library preparation process needs to be kept in a sealed state and completely isolated from the external environment to ensure that the sample will not be contaminated. Therefore, it is required that the opening and closing actions of the hot cover cannot destroy the sealing of the entire cassette.

[0004] It can be seen that the biggest difficulty encountered in applying the hot cover technology in the library preparation process is the need to achieve a large range of movable displacement of the hot cover to provide sufficient operating space, and at the same time, it is necessary to ensure that the displacement of the hot cover does not destroy the sealing integrity of the cartridge at any stage. Furthermore, for disposable cartridges, excessively high production costs are unacceptable, so the hot cover structure also needs to ensure low production costs and processing difficulty. In addition, the volume of the hot cover structure cannot be too large, otherwise it will be difficult to apply to cartridges with limited internal space. Summary of the invention

[0005] In order to solve the deficiencies of the prior art, the present invention proposes a single-degree-of-freedom flip displacement fully sealed hot cover system and a driving method, which drives the hot cover inside the cartridge to perform a single-degree-of-freedom flip displacement through a separate external displacement driving structure, thereby realizing the required hot cover displacement activity and ensuring that there is sufficient effective operating space above the PCR tube for the operation of other functional components such as a pipette after the hot cover is opened; the hot cover separately arranged in the cartridge can simply use elastic sealing materials to ensure the sealing of the cartridge during the displacement process, and is simple to manufacture and low in cost, especially with its small size and is suitable for use in instruments with cramped internal space, and is an ideal hot cover heating solution for the library preparation process.

[0006] To achieve the above objectives, the technical solutions adopted by the present invention include:

[0007] A flip displacement fully sealed thermal cover system, characterized by comprising a thermal cover and a displacement drive module which are not fixedly connected to each other;

[0008] The heat cover is disposed on the wall of the cartridge in a sealable manner that can be flipped and displaced by means of a rotating shaft and an elastic seal, and when the heat cover is flipped to a horizontal state, it faces and is aligned with the reaction well that needs to be heated;

[0009] The displacement driving module is arranged outside the card box and drives the thermal cover to perform flip displacement.

[0010] Furthermore, the thermal cover stays in the thermal cover open position by the elasticity of the elastic sealing member when not subjected to external force, and the thermal cover open position is the position where the thermal cover is flipped and lifted up and displaced to a limit position; the displacement driving module provides external force to drive the thermal cover to move and stay in the thermal cover closed position, and the thermal cover closed position is the position where the thermal cover is flipped down and displaced to a horizontal state limit position and covers and closes the reaction hole.

[0011] Furthermore, the elastic seal comprises an elastic member of a thin film structure that can be stretched and deformed, and the elastic seal maintains a contracted state when not acted upon by an external force and provides a force tending to return to the contracted state when stretched by an external force.

[0012] Furthermore, the elastic sealing element includes a silicone film or a soft rubber film.

[0013] Furthermore, the displacement driving module at least drives the thermal cover to flip, lower, displace, cover, close and press the reaction hole.

[0014] Furthermore, the thermal cover comprises a flap assembly, the bottom of which is connected to the cartridge via a rotating shaft in a flippable manner when the thermal cover is in an open position, a cover body corresponding to the reaction hole is provided at the top opposite to the rotating shaft, and a straight-line distance from the reaction hole to the rotating shaft is equal to a straight-line distance from the cover body to the rotating shaft; the side of the flap assembly facing outside the cartridge is completely covered with an elastic sealing member connected to the outer side of the cartridge wall.

[0015] Furthermore, the displacement driving module includes a push rod and a pressure plate, the push rod pushes the flap assembly to flip and lower the displacement by horizontal entry displacement, and the pressure plate pushes the flap assembly to cover, close and press the reaction hole by vertical downward displacement; a heating assembly is provided at one end of the pressure plate contacting the cover body.

[0016] Furthermore, the displacement driving module further comprises a fixing seat fixedly arranged relative to the card box, and a first driving motor, a second driving motor, a horizontal transmission block and a vertical transmission block installed on the fixing seat;

[0017] The first driving motor rotates forward and reversely according to the control instruction to drive the horizontal transmission block to drive the push rod and the pressure plate to move in the horizontal direction;

[0018] The second driving motor drives the vertical transmission block to rotate forward and reverse according to the control instruction, driving the pressure plate to move in the vertical direction.

[0019] Furthermore, the push rod is fixedly connected to the horizontal transmission block, the pressure plate is fixedly connected to the vertical transmission block, the vertical transmission block is connected to the horizontal transmission block via a vertical guide rail and is limited to vertical displacement relative to the horizontal transmission block, and the horizontal transmission block is connected to the fixed seat via a horizontal guide rail and is limited to horizontal displacement relative to the fixed seat.

[0020] Furthermore, the first drive motor and the second drive motor are configured to set a movement zero point via a photoelectric switch.

[0021] Furthermore, a roller is provided at the end of the push rod that contacts and pushes against the flap assembly.

[0022] Furthermore, the heating component includes a PI heating film, a ceramic heating plate, a Peltier, a silicone heating plate or a mica heating plate.

[0023] Furthermore, the heating component is also provided with a temperature sensor.

[0024] The present invention also relates to a flip displacement fully sealed thermal cover driving method, characterized in that a first driving motor and a second driving motor are used to respectively drive the thermal cover to perform flip displacement and press / relax reaction holes to complete a thermal cover closing displacement operation or a thermal cover opening displacement operation.

[0025] Furthermore, the thermal cover closing displacement operation includes the first drive motor rotating forward to drive the thermal cover to flip and lower and displace to just above the reaction hole, and the second drive motor rotating forward to drive the thermal cover to cover and press the reaction hole; the thermal cover opening displacement operation includes the second drive motor rotating reversely to release the driving force on the thermal cover so that the thermal cover releases the reaction hole, and the first drive motor rotating reversely to release the driving force on the thermal cover and at the same time drive the thermal cover to flip and lift and displace to make room just above the reaction hole through the force of the elastic sealing member tending to return to the contracted state.

[0026] Furthermore, the thermal cover closing displacement operation includes the first driving motor rotating forward to drive the push rod to move horizontally, push against the thermal cover, flip and lower it to move directly above the reaction hole, and the second driving motor rotating forward to drive the pressing plate to move vertically downward, push against the thermal cover to cover and press the reaction hole; the thermal cover opening displacement operation includes the second driving motor rotating reversely to drive the pressing plate to move vertically upward and stop pushing against the thermal cover, so that the thermal cover releases the reaction hole, and the first driving motor rotating reversely to drive the push rod to move horizontally out of the thermal cover and stop pushing against the thermal cover, so that the thermal cover is driven by the force of the elastic sealing member tending to return to the contracted state to perform flipping and lifting displacement to make room for the space directly above the reaction hole.

[0027] The beneficial effects of the present invention are:

[0028] The flip-displacement fully sealed hot cover system and the driving method of the present invention are used to cover and heat the reaction wells in the library preparation process, which can ensure the integrity of the sealing of the cartridge while realizing the flipping single-degree-of-freedom displacement of the hot cover structure according to the operation needs, without affecting the operation of the reaction wells by other functional components in the cartridge, thereby avoiding external contamination of the sample due to the hot cover displacement; at the same time, there is no rigid connection between the displacement driving module and the hot cover, and the high-cost displacement driving module can be easily and independently arranged outside the cartridge, thereby greatly reducing the manufacturing cost and manufacturing difficulty of the cartridge, and the overall structure is small in size, which is more suitable for making disposable cartridges, and a higher-precision driving component can also be used as needed to improve the efficiency and accuracy of the library preparation experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 It is a three-dimensional schematic diagram of a preferred embodiment of the flip displacement fully sealed thermal cover system of the present invention.

[0030] Figure 2 This is a schematic diagram of the opening position of the hot cover in a preferred embodiment of the present invention.

[0031] Figure 3 This is a schematic diagram of the hot cover being flipped down in a preferred embodiment of the present invention.

[0032] Figure 4 This is a schematic diagram of the closed position of the thermal cover in a preferred embodiment of the present invention.

[0033] Figure 5 This is a schematic diagram of the cover assembly in the open position of the thermal cover according to a preferred embodiment of the present invention.

[0034] Figure 6 This is a schematic diagram of the cover assembly of the thermal cover in the closed position according to a preferred embodiment of the present invention.

[0035] Explanation of the accompanying figures: 11-rotating shaft, 12-flip plate assembly, 13-elastic sealing member, 21-pressing plate, 212-heating assembly, 213-temperature sensor, 22-push rod, 23-fixed seat, 24-first drive motor, 25-second drive motor, 26-horizontal transmission block, 261-horizontal guide rail, 27-vertical transmission block, 271-vertical guide rail, 28-photoelectric switch, 3-reaction hole, 4-card box. DETAILED DESCRIPTION

[0036] In order to more clearly understand the content of the present invention, it will be described in detail with reference to the drawings and embodiments.

[0037] When using a hot cover system to heat the reaction wells during library preparation, it is necessary to ensure that the sealing of the library preparation cartridge is intact and that the operability of other functional components is not affected. In essence, the hot cover (cover assembly) is not only required to perform a single-dimensional vertical displacement to normally close and open the hot cover, but also to provide an appropriate displacement method to ensure that the hot cover is opened to allow the operating space directly above the reaction well for other functional components in the cartridge (such as a pipette) to operate the reaction well. More complex displacement requirements not only cause problems for the cartridge sealing, but also directly lead to a more complex and more expensive hot cover structure, which is not well suited for disposable cartridges.

[0038] In order to solve the relative contradiction between the complex displacement, sealing and low cost of the thermal cover system, the present invention adopts a solution in which the thermal cover and the displacement drive module are separately arranged. The thermal cover is directly arranged on the cartridge by an elastic seal, forming a whole with the cartridge (the wall of the cartridge), ensuring the sealing of the cartridge, and using an external displacement drive module to drive the thermal cover to perform the required displacement to realize the thermal cover function. While solving the complex displacement and sealing problems, the external displacement drive module can be reused, reducing the cost of the cartridge part (disposable part), and breaking away from the premise of cost constraints also facilitates the use of more efficient drive components as needed, which helps to improve the efficiency and accuracy of library preparation.

[0039] Figures 1 to 4A preferred embodiment of the flip displacement fully sealed thermal cover system of the present invention is provided, which mainly comprises a thermal cover and a displacement driving module. The thermal cover part comprises a flap assembly 12 and an elastic sealing member 13, and one side of the flap assembly 12 is rotatably connected to the wall of the cartridge 4 via a rotating shaft 11, so that the flap assembly 12 can be flipped and displaced by about 90° relative to the cartridge 4 (the wall of the cartridge 4) and the reaction hole 3 under the action of an external force. Figure 5 and Figure 6 As shown, in a preferred embodiment, the hot cover open position is a position where the flap assembly 12 is flipped up and nearly vertical, and the hot cover closed position is a position where the flap assembly 12 is flipped down and the end cover is aligned parallel to the reaction hole 3. On the flap assembly 12, the cover is arranged on the other side opposite to the rotation axis 11, so the straight-line distance from the cover to the rotation axis 11 is equal to the straight-line distance from the reaction hole 3 to the rotation axis 11. When the flipping movement is performed with the rotation axis 11 as the axis, the cover and the reaction hole 3 are on the same circular path, and then the requirements of aligning the hot cover with the reaction hole 3 and removing the hot cover to release the operating space directly above the reaction hole 3 can be achieved through the flipping displacement with a single degree of freedom.

[0040] Preferably, in the absence of additional external forces, the flap assembly 12 is maintained in the open position of the thermal cover by the elasticity of the elastic seal 13 itself, and the elasticity of the elastic seal 13 can provide a force tending to return to the open position of the thermal cover when it is displaced by an external force. The elastic seal 13 preferably completely covers the side of the card box 4 connected to the thermal cover (flip assembly 12) to provide sufficient sealing. According to requirements, the elastic seal 13 can be a thin film structure elastic member made of a material such as a silicone film or a soft rubber film. Since the card box 4 is disposable, the elastic seal 13 does not particularly need to consider the durability of use. In fact, in order to better control costs, the elastic seal 13 can be selected from components with relatively low performance but low cost while meeting the use requirements. In a preferred embodiment, the heating function is not integrated into the heat cover part, and this is also to better control the cost of the card box 4. By integrating the heating function into an external component, it can be reused and waste can be avoided. Of course, those skilled in the art should be able to understand without any obstacles that integrating the heating function into the heat cover part, such as directly integrating it into the flap assembly 12, is conceivable and easy to implement, and will not affect the main technical solution of the present invention.

[0041] Through the above-mentioned thermal cover part, the sealing problem of the card box 4 can be solved, and the manufacturing cost of the card box 4 can also be well controlled. On this basis, the external displacement drive module does not have strict cost restrictions, so a suitable drive structure can be selected according to needs. In a preferred embodiment, a dual-motor drive structure is adopted, which converts the positive and negative rotation of the motor into a linear displacement of the pressure plate 21 and the push rod 22, and then drives the thermal cover to perform a predetermined displacement by pushing. Among them, the first drive motor 24 is used to provide horizontal displacement power, and the second drive motor 25 is used to provide vertical displacement power. In a preferred embodiment, the pressure plate 21 and the push rod 22 perform horizontal displacement synchronously, but only the pressure plate 21 performs vertical displacement corresponding to the rotation of the second drive motor 25. Therefore, there is a subordinate relationship between the first drive motor 24 and the second drive motor 25, that is, the first drive motor 24 has the highest execution level. When the first drive motor 24 rotates, the pressure plate 21, the push rod 22 and the second drive motor 25 all perform corresponding horizontal displacements. At the same time, the second drive motor 25 will not affect the push rod 22 and the first drive motor 24 when rotating, and only drives the pressure plate 21 to perform corresponding vertical displacements. In terms of structure, a horizontal transmission block 26 and a vertical transmission block 27 with corresponding displacement direction limits are used for connection. The pressing plate 21 is fixedly arranged on the vertical transmission block 27. The vertical transmission block 27 is connected to the horizontal transmission block 26 through a vertical guide rail 271 and can be vertically displaced relative to the horizontal transmission block 26. The push rod 22 and the second driving motor 25 are both fixedly arranged on the horizontal transmission block 26. The horizontal transmission block 26 is connected to the fixing seat 23 through a horizontal guide rail 261 and can be horizontally displaced relative to the fixing seat 23. The first driving motor 24 is fixedly arranged on the fixing seat 23. When the displacement operation is required, the first driving motor 24 rotates to drive the horizontal transmission block 26 to perform horizontal displacement, and then the second driving motor 25, the push rod 22, the vertical transmission block 27, the vertical guide rail 271 and the pressing plate 21 arranged on the horizontal transmission block 26 all perform horizontal displacement synchronously; the second driving motor 25 rotates to drive the vertical transmission block 27 to perform vertical displacement, and only drives the pressing plate 21 arranged on the vertical transmission block 27 to perform vertical displacement synchronously. Preferably, the first drive motor 24 and the second drive motor 25 can be controlled by a photoelectric switch 28, so as to achieve high-precision displacement control.

[0042] Through the displacement drive module of the above structure, the pressing plate 21 and the push rod 22 can be displaced as needed, and the heating component 213 arranged at one end of the pressing plate 21 can align with the contact and press the flap assembly 12 when the pressing plate 21 is vertically displaced downward, thereby forming a complete hot cover with heating capability, thereby realizing the closed heating operation of the reaction hole 3; preferably, a temperature sensor 214 is arranged at a position close to the heat source on the heating component 213, and the heating component 213 can be controlled according to the real-time temperature detected by the temperature sensor 214, thereby flexibly adjusting the heating temperature of the hot cover (reaction hole 3). As mentioned above, the main purpose of arranging the heating component 213 on the pressing plate 21 is to further reduce the cost and structural complexity of the cartridge 4, and to realize the reusability of more functional components as much as possible. According to actual needs, the design of integrating the heating component 213 on the flap assembly 12 (integrated into the cartridge 4) can also be adopted.

[0043] Since the push rod 22 needs to push the heat cover, in order to avoid scratching or wearing the elastic seal 13, a roller is preferably provided at the end of the push rod 22, and a smooth and smooth pushing action can be achieved through the contact rotation of the roller, and the elastic seal 13 can be protected.

[0044] When using the thermal cover system as shown in the preferred embodiment, the thermal cover (flap assembly 12) is normally in the thermal cover open position. According to the control instruction, the first drive motor 24 rotates forward to drive the pressure plate 21 and the push rod 22 to move horizontally. At this time, the push rod 22 contacts and pushes against the thermal cover (flap assembly 12), pushing the flip assembly 12 to flip and lower the displacement; when the push rod 22 drives the thermal cover to the preset position so that the cover body is vertically aligned with the reaction hole 3, the second drive motor 25 rotates forward to drive the pressure plate 21 to move vertically downward, and the pressure plate 21 pushes against and presses the thermal cover (flap assembly 12) to close the reaction hole 3, and the thermal cover remains in the thermal cover closed position. When the heating process is finished, according to the control instruction, the second drive motor 25 rotates in the opposite direction to drive the pressure plate 21 to perform a vertical upward displacement, releasing the contact with the heat cover (flip assembly 12), and the flip assembly 12 completely detaches from the reaction hole 3 under the elastic restoring force of the elastic seal 13; the first drive motor 24 rotates in the opposite direction to drive the pressure plate 21 and the push rod 22 to withdraw horizontally, and the push rod 22 releases the pushing force on the heat cover (flip assembly 12), and the flip assembly 12 is flipped and lifted up to return to the heat cover open position driven by the restoring force of the elastic seal 13.

[0045] The above preferred embodiment can realize the use of dual motors to drive the heat cover to perform flip displacement and heating component pressing operations, but if Figures 1 to 6 The specific structure shown is only a schematic structure for technicians to understand the technical solution of the present invention. When applying the present invention, those skilled in the art can select any suitable driving structure to achieve the flipping single-degree-of-freedom displacement of the thermal cover according to needs.

[0046] The above is only a preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any changes or substitutions that can be easily thought of by a person skilled in the art within the technical scope disclosed by the present invention should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. A flip displacement fully sealed thermal cover system, characterized in that: It includes a thermal cover and a displacement drive module that are not fixedly connected to each other; The heat cover is disposed on the wall of the cartridge in a sealable manner that can be flipped and displaced by means of a rotating shaft and an elastic seal, and when the heat cover is flipped to a horizontal state, it faces and is aligned with the reaction well that needs to be heated; The displacement driving module is arranged outside the card box and drives the thermal cover to perform flip displacement; The displacement drive module includes: a dual-motor drive structure, wherein the first drive motor provides horizontal displacement power, and the second drive motor provides vertical displacement power; the pressing plate and the push rod synchronously perform horizontal displacement, and the pressing plate performs vertical displacement corresponding to the rotation of the second drive motor; when the first drive motor rotates, the pressing plate, the push rod and the second drive motor all perform corresponding horizontal displacement, and the second drive motor only drives the pressing plate to perform corresponding vertical displacement when rotating; The thermal cover is stopped at the thermal cover opening position by the elasticity of the elastic sealing member when no external force is applied thereto, and the thermal cover opening position is the position where the thermal cover is flipped and lifted up and displaced to the limit position; the displacement driving module provides external force to drive the thermal cover to move and stop at the thermal cover closing position, and the thermal cover closing position is the position where the thermal cover is flipped down and displaced to the horizontal state limit position and covers and closes the reaction hole; The elastic sealing member comprises an elastic member of a film structure that can be stretched and deformed, and the elastic sealing member maintains a contracted state when not acted upon by an external force and provides a force tending to return to the contracted state when stretched by an external force.

2. The system according to claim 1, characterized in that The elastic sealing element includes a silicone film or a soft rubber film.

3. The system according to claim 1, characterized in that The displacement driving module at least drives the thermal cover to flip and lower the displacement and cover, close and press the reaction hole.

4. The system according to claim 3, characterized in that The thermal cover comprises a flap assembly, wherein the bottom of the flap assembly is connected to the cartridge via a rotating shaft in a flippable manner when the thermal cover is in an open position, a cover body corresponding to the reaction hole is arranged at the top opposite to the rotating shaft, and a straight-line distance from the reaction hole to the rotating shaft is equal to a straight-line distance from the cover body to the rotating shaft; the side of the flap assembly facing the outside of the cartridge is completely covered with an elastic sealing member connected to the outer side of the cartridge wall.

5. The system according to claim 4, characterized in that The displacement driving module includes a push rod and a pressure plate. The push rod pushes the flap assembly to flip and lower the displacement by horizontal entry displacement, and the pressure plate pushes the flap assembly to cover, close and press the reaction hole by vertical downward displacement. A heating component is provided at one end of the pressure plate contacting the cover body.

6. The system according to claim 5, characterized in that The displacement driving module also includes a fixing seat fixedly arranged relative to the card box, and a first driving motor, a second driving motor, a horizontal transmission block and a vertical transmission block installed on the fixing seat; The first driving motor rotates forward and reversely according to the control instruction to drive the horizontal transmission block to drive the push rod and the pressure plate to move in the horizontal direction; The second driving motor drives the vertical transmission block to rotate forward and reverse according to the control instruction, driving the pressure plate to move in the vertical direction.

7. The system according to claim 6, characterized in that The push rod is fixedly connected to the horizontal transmission block, the pressure plate is fixedly connected to the vertical transmission block, the vertical transmission block is connected to the horizontal transmission block via a vertical guide rail and is limited to vertical displacement relative to the horizontal transmission block, and the horizontal transmission block is connected to the fixed seat via a horizontal guide rail and is limited to horizontal displacement relative to the fixed seat.

8. The system according to claim 6, characterized in that The first drive motor and the second drive motor are set to move at zero points via photoelectric switches.

9. The system according to claim 5, characterized in that The end of the push rod that contacts and pushes against the flap assembly is provided with a roller.

10. The system according to any one of claims 5 to 9, characterized in that The heating component includes a PI heating film, a ceramic heating sheet, a Peltier, a silica gel heating sheet or a mica heating sheet.

11. The system according to any one of claims 5 to 9, characterized in that: The heating component is also provided with a temperature sensor.

12. A method for driving a flip displacement fully sealed thermal cover, characterized in that: Using the flip displacement fully sealed thermal cover system as described in any one of claims 1 to 11; The first driving motor and the second driving motor are used to respectively drive the hot cover to perform flipping displacement and to press / relax the reaction hole to complete the hot cover closing displacement operation or the hot cover opening displacement operation.

13. The method according to claim 12, characterized in that The thermal cover closing displacement operation includes the first driving motor rotating forward to drive the thermal cover to flip and lower and displace to above the reaction hole, and the second driving motor rotating forward to drive the thermal cover to cover and press the reaction hole; the thermal cover opening displacement operation includes the second driving motor rotating reversely to release the driving force on the thermal cover so that the thermal cover releases the reaction hole, and the first driving motor rotating reversely to release the driving force on the thermal cover and at the same time drive the thermal cover to flip and lift and displace to make room above the reaction hole through the force of the elastic sealing member tending to return to the contracted state.

14. The method according to claim 13, characterized in that The heat cover closing displacement operation includes the first drive motor rotating forward to drive the push rod to move horizontally, push the heat cover, flip and lower it to move it to the top of the reaction hole, and the second drive motor rotating forward to drive the pressing plate to move vertically downward, push the heat cover to cover and press the reaction hole; the heat cover opening displacement operation includes the second drive motor rotating reversely to drive the pressing plate to move vertically upward and stop pushing the heat cover, so that the heat cover releases the reaction hole, and the first drive motor rotating reversely to drive the push rod to move horizontally out of the heat cover and stop pushing the heat cover, so that the heat cover is driven by the force of the elastic sealing member tending to return to the contracted state to perform flipping and lifting displacement to make room for the space directly above the reaction hole.

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