Vacuum quantitative concentration device and concentration method

Abstract

The invention relates to a vacuum quantitative concentration device and a concentration method. The device comprises a concentration cup, a vacuum module, an oscillation module, a water bath heating module, a waste gas recovery module, a condensation reflux module, a low temperature anti-evaporation module and a control module. A tail pipe is arranged at the lower end of the concentration cup, so that a sample solution is concentrated by centrifugal oscillation and rotary evaporation in a vacuum environment, wherein the condensation reflux module can further improve the concentration effect in the sample solution, and the low temperature anti-evaporation module keeps the tail pipe located at the lower part of the concentration cup at a low temperature to prevent the sample solution in the concentration cup from being completely evaporated. The whole process is automatically coordinated by the control module with the vacuum module, the oscillation module, the water bath heating module, the waste gas recovery module and the reflux module as well as the low temperature anti-evaporation module, so as to realize automatic concentration of the sample solution in the concentration cup with high efficiency and high recovery rate.

Description

Technical Field

[0001] The invention relates to the technical field of sample analysis and testing, and in particular to a vacuum quantitative concentration device and a concentration method. Background Art

[0002] In the laboratory, solvent concentration is usually carried out by rotary evaporator or nitrogen blowing concentrator. When using rotary evaporator, only one sample can be concentrated at a time, and the experimenter needs to check frequently during the concentration process to prevent the solvent from drying up and affecting the sample recovery rate. Nitrogen blowing concentrator cannot recycle waste gas, which is not environmentally friendly and has a low sample recovery rate. In addition, both of the above two concentration methods have the risk of the target solution being evaporated to dryness. Therefore, we specially propose a vacuum quantitative concentration device and concentration method to solve the above problems. Summary of the invention

[0003] The purpose of the present invention is to provide a vacuum quantitative concentration device and a concentration method in view of the deficiencies in the prior art, which can well solve the above-mentioned problems.

[0004] In order to achieve the above requirements, the technical solution adopted by the present invention to solve its technical problems is:

[0005] Provided is a vacuum quantitative concentration device, comprising a concentration cup for containing a sample solution, wherein a tail tube is provided at the lower end of the concentration cup;

[0006] The vacuum module evacuates the air inside the concentration cup to form a vacuum above the sample solution in the concentration cup.

[0007] An oscillating module oscillates the concentration cup to accelerate the flow of the sample solution inside the concentration cup;

[0008] A water bath heating module is used to heat the middle part of the concentration cup in a water bath, so that the impurity solution contained in the sample solution in the concentration cup is evaporated by heat, thereby concentrating the sample solution;

[0009] Waste gas recovery module, used to collect impurity solution evaporated by heat;

[0010] A condensation reflux module condenses and cools the upper part of the concentration cup, so that the target solution carried by the evaporated impurity solution vapor is cooled, condensed and refluxed to the concentration cup;

[0011] A low temperature anti-evaporation module is used to keep the tail tube located at the bottom of the concentration cup at a low temperature to prevent the sample solution in the concentration cup from being completely evaporated;

[0012] The control module is used to coordinate the vacuum module, the oscillation module, the water bath heating module, the waste gas recovery module, the reflux module and the low-temperature anti-evaporation module to achieve concentration of the sample solution in the concentration cup.

[0013] The vacuum quantitative concentration device of the present invention further comprises:

[0014] The fixed cover is used for fixing the concentrated cup and has a heating element inside.

[0015] The vacuum quantitative concentration device of the present invention, wherein the concentration cup is provided in plurality and all are arranged on the bottom surface of the fixed cover;

[0016] The fixed cover is provided with a channel corresponding to the concentration cup for allowing evaporated impurity solution steam and vacuumed air to pass through.

[0017] In the vacuum quantitative concentration equipment of the present invention, the water bath heating module is a water heating box, and the lower end of the concentration cup passes through the bottom of the water heating box.

[0018] The vacuum quantitative concentration equipment of the present invention, wherein a heat insulating member is provided between the low-temperature evaporation prevention module and the water bath heating module, the low-temperature evaporation prevention module comprises a base, a receiving groove and a low-temperature circulating water channel are provided on the base corresponding to the tail pipe, and the low-temperature evaporation prevention module also comprises a water circulation pipe group arranged corresponding to the low-temperature circulating water channel.

[0019] In addition, a concentrating method of a vacuum quantitative concentrating device is also provided, the method comprising the following steps:

[0020] The inner cavity of the concentration cup is divided into a constant diameter area and a variable diameter area from top to bottom, wherein the variable diameter area is a truncated cone transition section connecting the concentration cup and the tail pipe;

[0021] Determining whether the liquid surface of the sample solution in the concentration cup is located in the constant diameter zone or the variable diameter zone;

[0022] When the liquid level of the sample solution is located in the constant diameter zone, executing the first concentration method to make the concentration rate of the sample solution constant;

[0023] When the liquid level of the sample solution is located in the diameter-changing region, the second concentration method is performed to make the concentration rate of the sample solution constant.

[0024] The concentrating method of the vacuum quantitative concentrating device of the present invention further comprises:

[0025] When the first concentration method is executed, in order to reduce the influence of condensation reflux on the concentration rate during the period of executing the first concentration method, a third concentration method is further executed to achieve rate influence compensation.

[0026] The concentration method of the vacuum quantitative concentration device of the present invention, wherein the third concentration method is:

[0027] The centrifugal oscillation rotation angular velocity W of the concentration cup is kept constant, and as the liquid level drops, the vacuum degree P above the liquid level is adjusted in real time according to a vacuum preset rule, wherein the vacuum preset rule is P=P0(1-Δh)t;

[0028] Among them, △h is the height that the liquid level drops per unit time, P0 is the initial vacuum degree above the liquid level, and t is the concentration time.

[0029] The concentration method of the vacuum quantitative concentration device of the present invention, wherein the first concentration method is: keeping the centrifugal oscillation rotation angular velocity W of the concentration cup constant, and keeping the temperature T and vacuum degree P of the constant diameter zone constant.

[0030] The concentration method of the vacuum quantitative concentration device of the present invention, wherein the second concentration method is:

[0031] Keep the internal vacuum degree P of the concentration cup constant, and adjust the centrifugal oscillation rotation angular velocity W of the sample solution in real time according to the preset oscillation rules. t , the preset oscillation rule is f(wt, rt)=kf(w0, r1);

[0032] in:

[0033] k is the reference coefficient, which can be obtained through multiple experiments;

[0034] is the calculation formula for the vortex surface area formed by the rotation of the sample solution surface, is a formula for expressing the vortex surface formed by the rotation of the sample solution liquid surface, g is the gravitational acceleration, R is the centrifugal oscillation rotation radius of the concentration cup, and r is the static liquid surface radius;

[0035] W0 is the initial centrifugal oscillation rotation angular velocity, r1 is the radius of the constant diameter zone, r t To adjust the radius of the circular surface formed by the liquid surface in the diameter-changing area in real time;

[0036] The r t By the identity V 初 -V 蒸发 =V 剩余 Solved, among which,

[0037] V 初 is the initial volume of the sample solution, is a constant,

[0038] is the volume of the remaining solution,

[0039] V 蒸发 is the volume that has evaporated easily, according to the formula V 蒸发 =t×V 速 get,

[0040] V 速 is the target concentration rate, is the preset constant,

[0041] t is the time of real-time adjustment, and t1 is the time when the liquid surface of the sample solution is completely located in the diameter-changing area;

[0042] h t To adjust the height of the liquid level in real time and through the formula Obtained, α is the angle between the inclined surface and the bottom surface of the truncated cone transition section.

[0043] The beneficial effects of the present invention are: it can realize vacuum concentration of multiple samples at the same time, perform three-stage temperature control on the concentration cup, realize the functions of preventing evaporation, water bath heating and cooling reflux, the centrifugal oscillation component can ensure uniform heating during the water bath heating process, realize efficient concentration while ensuring the recovery rate, and the waste gas can be recovered in real time. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the present invention will be further described below in conjunction with the accompanying drawings and embodiments. The drawings described below are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative work:

[0045] Figure 1 It is a schematic diagram of the overall structure of the vacuum quantitative concentration device of the present invention.

[0046] Figure 2 It is an exploded view of the vacuum quantitative concentration device of the present invention.

[0047] Figure 3 yes Figure 2 Enlarged view of point A in the middle.

[0048] Figure 4 It is a longitudinal sectional view of the vacuum quantitative concentration device of the present invention.

[0049] Figure 5 It is a schematic diagram of the temperature zone distribution of the concentration cup of the vacuum quantitative concentration equipment of the present invention.

[0050] Figure 6 This is a diagram of the parameters of the concentration cup of the vacuum quantitative concentration device of the present invention.

[0051] Figure 7 It is a schematic diagram of the rotation trajectory of the concentration cup of the vacuum quantitative concentration device of the present invention.

[0052] Figure 8 It is a schematic diagram of the vortex surface coordinates of the sample liquid surface of the vacuum quantitative concentration device of the present invention.

[0053] Fig. 9 It is a flow chart of the steps of the concentration method of the vacuum quantitative concentration equipment of the present invention. DETAILED DESCRIPTION

[0054] The terms "first", "second", "third" and "fourth" etc. in the specification and claims of the present invention and the drawings are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device that includes a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units that are not listed, or may optionally include other steps or units that are inherent to these processes, methods, products or devices.

[0055] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present invention. The appearance of the phrase in various places in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0056] "Multiple" means two or more. "And / or" describes the relationship between related objects, indicating that there can be three relationships. For example, A and / or B can mean: A exists alone, A and B exist at the same time, and B exists alone. The character " / " generally indicates that the related objects are in an "or" relationship.

[0057] Moreover, the terms "up, down, left, right, upper end, lower end, longitudinal" and the like indicating directions are all based on the posture and position of the device or equipment described in this solution during normal use.

[0058] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the following will be described clearly and completely in combination with the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are partial embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work belong to the protection scope of the present invention.

[0059] The vacuum quantitative concentration device of the preferred embodiment of the present invention is as follows Figure 1-7 As shown, the device includes a concentration cup 1 for containing a sample solution, and a tail tube 1a is provided at the lower end of the concentration cup 1. The diameter of the tail tube 1a is smaller than the diameter of the concentration cup 1, and the two are transitionally connected by a cone 1b.

[0060] The device also includes a vacuum module 2, which is used to evacuate the air inside the concentration cup 1, so that a vacuum is formed above the sample solution in the concentration cup 1. The vacuum environment can reduce the boiling point of the sample solution, thereby accelerating the concentration rate.

[0061] The device also includes an oscillation module 3, which performs centrifugal rotation and oscillation on the concentration cup 1 to accelerate the horizontal flow of the sample solution inside the concentration cup 1. Increasing the flow rate of the solution can effectively increase the concentration rate. The faster the oscillation speed, the larger the vortex surface formed by the liquid surface, and the faster the concentration speed.

[0062] The device also includes a water bath heating module 4, which performs water bath heating on the middle part of the concentration cup 1, so that the impurity solution contained in the sample solution in the concentration cup 1 is evaporated by heat, thereby concentrating the sample solution. The water bath heating can ensure that the sample solution is evenly heated.

[0063] The device also includes an exhaust gas recovery module 5 for collecting the impurity solution vapor evaporated by heat to achieve the purpose of environmental friendliness;

[0064] The device also includes a condensation reflux module 6, which is used to condense and cool the upper part of the concentration cup 1, so that the target solution carried by the evaporated impurity solution vapor is cooled and condensed and refluxed along the inner wall of the concentration cup 1, thereby achieving repeated concentration, greatly improving the concentration effect;

[0065] The device also includes a low-temperature anti-evaporation module 7, which keeps the tail tube 1a located at the bottom of the concentration cup 1 at a low temperature to prevent the sample solution in the concentration cup 1 from being completely evaporated;

[0066] The device also includes a control module 8 for coordinating and controlling the vacuum module 2, the oscillation module 3, the water bath heating module 4, the waste gas recovery module 5, the reflux module and the low-temperature anti-evaporation module 7, so as to concentrate the sample solution in the concentration cup 1, facilitate the concentration of the automated process, and facilitate human-computer interaction to realize the modification and adjustment of various concentration parameters.

[0067] Under a certain vacuum condition, the liquid in the concentration cup 1 is heated and shaken in a water bath to achieve heat exchange. The liquid in the concentration cup 1 is heated to become gaseous and discharged by the vacuum pump of the waste gas recovery module 5. When the liquid is heated and evaporates rapidly, it will carry a part of the low-boiling point target, which will affect the sample recovery rate. The present invention prevents the low-boiling point target from overflowing by forcibly cooling the upper cup body of the concentration cup 1, thereby retaining the low-boiling point target.

[0068] When the sample is concentrated to a small amount of liquid, since the tail tube 1a of the concentration cup 1 is located at the low-temperature water bath position of the anti-evaporation module, the liquid temperature is low, which greatly reduces the volatilization effect of the liquid, thereby ensuring that the liquid is not concentrated to dryness for a long time, thereby ensuring the retention of the target object, improving the recovery rate and the parallelism between samples.

[0069] Preferably, the device further comprises:

[0070] The fixed cover 9 is used to fix the concentration cup 1 and is provided with a heating element (not shown) inside, which can effectively solve the problem of sample cross contamination caused by condensation and reflux of concentrated waste gas.

[0071] Preferably, there are multiple concentration cups 1 and all are arranged on the bottom surface of the fixed cover, wherein the fixed cover is provided with channels 10 corresponding to the concentration cups 1 for allowing the evaporated impurity solution steam and the vacuumed air to pass through.

[0072] Preferably, the water bath heating module 4 is a water heating box, and the lower end of the concentration cup 1 passes through the bottom of the water heating box so that the tail pipe 1a extends into the low-temperature holding position of the low-temperature anti-evaporation module 7. During the actual installation process, it is necessary to ensure that the outer wall of the concentration cup 1 and the bottom surface of the water tank are sealed to prevent water leakage in the water tank.

[0073] Preferably, a heat insulating member 11 is provided between the low-temperature anti-evaporation module 7 and the water bath heating module 4. The low-temperature anti-evaporation module 7 includes a base 71. The base 71 is provided with a receiving groove 12 and a low-temperature circulating water channel (not shown) connected thereto corresponding to the tail pipe 1a. When assembled in place, the tail pipe 1a passes through the receiving groove 12 and extends into the low-temperature circulating water channel (not shown). Furthermore, the low-temperature anti-evaporation module 7 also includes a water circulation pipe group 72 arranged corresponding to the low-temperature circulating water channel (not shown) to realize water circulation.

[0074] The concentration method of the vacuum quantitative concentration device of the preferred embodiment of the present invention is as follows: Figure 8 As shown, the method comprises the following steps:

[0075] Step S1: dividing the inner cavity of the concentrate cup 1 into a constant diameter area 100 and a variable diameter area 200 from top to bottom, wherein the variable diameter area is a truncated cone transition section connecting the concentrate cup 1 and the tail pipe 1a;

[0076] Step S2: determining whether the liquid surface of the sample solution in the concentration cup 1 is located in the constant diameter area or the variable diameter area;

[0077] When the liquid level of the sample solution is in the constant diameter region, executing the first concentration method to make the concentration rate of the sample solution constant;

[0078] When the liquid level of the sample solution is located in the diameter-changing region, the second concentration method is performed to make the concentration rate of the sample solution constant.

[0079] Preferably, the method further comprises:

[0080] When the first concentration method is executed, in order to reduce the influence of condensation reflux on the concentration rate during the period of executing the first concentration method, the third concentration method is further executed to achieve rate influence compensation.

[0081] In actual concentration, there are four conditions that affect the concentration rate:

[0082] 1. Temperature T. The higher the temperature, the faster the concentration rate.

[0083] 2. Oscillation speed W. The faster the oscillation speed, the larger the vortex surface formed by the liquid and the faster the concentration rate.

[0084] 3. Vacuum degree P. The lower the vacuum degree, the lower the boiling point of the solution and the faster the concentration rate.

[0085] 4. The area S of the gas-liquid contact (i.e., the vortex surface 300 of the liquid surface) is such that the larger the contact area, the faster the concentration rate. That is, the larger the inner diameter of the concentration cup 1, the faster the concentration rate.

[0086] Preferably, the third concentration method is:

[0087] The centrifugal oscillation rotation angular velocity W of the concentration cup 1 is kept constant. As the liquid level drops, the vacuum degree P above the liquid level is adjusted in real time according to the vacuum preset rule. The vacuum preset rule is P=P0(1-Δh)t;

[0088] Among them, let the initial liquid level be H, △h be the height that the liquid level drops in unit time, P0 be the initial vacuum degree above the liquid level (the initial vacuum degree P0 can refer to the vapor pressure value of the solvent at different temperatures), and t be the concentration time.

[0089] In the actual concentration process, when the liquid level in the constant diameter zone gradually decreases, the amount of liquid condensation reflux increases, which will hinder the vortex surface and reduce the concentration rate. Therefore, when the liquid is concentrated, the vacuum degree P is reduced as the liquid level decreases, thereby compensating for the reduction in concentration rate caused by condensation reflux.

[0090] Preferably, the first concentration method is: keep the centrifugal oscillation rotation angular velocity W of the concentration cup 1 constant, and keep the temperature T and vacuum degree P of the constant diameter zone constant; in practice, the centrifugal oscillation component of the oscillation module 3 performs eccentric circular motion driven by the motor, the water bath heating module 4 is fixed to the centrifugal oscillation component, and the concentration cup 1 is placed in the water bath heating hole of the water bath heating module 4, so the concentration cup 1 also performs eccentric circular motion during the concentration process, and the specific trajectory is as follows: Figure 7 As shown, without considering the viscosity of the liquid in the cup, the centrifugal oscillation vortex surface formed by the rotation of the liquid in the concentration cup 1 is a parabola, which can be expressed by the formula Where g is the acceleration due to gravity, w is the angular velocity of rotation, and r is the radius of the stationary liquid surface (i.e., the radius of the concentrate cup 1). The area of ​​this vortex surface can be expressed by the formula It can be seen that the area of ​​the vortex surface is only related to the parameters w and r, and the radius of the actual product concentration cup 1 is fixed, so it is only related to w, that is, the inner diameter of the concentration cup 1 in the constant diameter area is consistent, and the size of the vortex surface is only related to the liquid properties and the centrifugal oscillation speed w. For the same liquid, when the centrifugal oscillation speed w and the vacuum degree p are constant, the obstruction of the reflux liquid during condensation reflux is not considered, and the concentration rate is constant.

[0091] Preferably, the second concentration method is:

[0092] At time t1, all the liquid is in the variable diameter area. As the radius of the concentration cup 1 decreases, the centrifugal vortex surface decreases. To ensure a constant concentration rate, the centrifugal oscillation speed W needs to be increased accordingly. t To this end, the internal vacuum degree P of the concentration cup 1 is kept constant, and the centrifugal oscillation rotation angular velocity W of the sample solution is adjusted in real time according to the preset oscillation rules. t , the oscillation preset rule is f(w t , r t ) = kf(w0, r1);

[0093] in:

[0094] k is the reference coefficient, which can be obtained through multiple experiments;

[0095] is the calculation formula for the vortex surface area formed by the rotation of the sample solution surface, is the expression formula of the vortex surface formed by the rotation of the sample solution liquid surface, g is the gravitational acceleration, R is the centrifugal oscillation rotation radius of the concentration cup 1, and r is the static liquid surface radius;

[0096] W0 is the initial centrifugal oscillation rotation angular velocity, r1 is the radius of the constant diameter zone, r t To adjust the radius of the circular surface formed by the liquid surface in the diameter-changing area in real time;

[0097] The rt is obtained by solving the identity Vinitial - Vevaporation = Vremaining, where

[0098] Vinitial is the initial volume of the sample solution, which is a constant.

[0099] is the volume of the remaining solution,

[0100] Vevaporation is the volume that has evaporated easily, obtained by the formula Vevaporation = t × Vspeed,

[0101] V speed is the target concentration rate, which is a preset constant.

[0102] t is the time of real-time adjustment, and t1 is the time when the liquid surface of the sample solution is completely located in the diameter-changing area;

[0103] ht is the height of the liquid level at the time of real-time adjustment and is expressed by the formula Obtained, α is the angle between the slope and the bottom of the transition section of the truncated cone, and the centrifugal oscillation speed W can be obtained by integrating the above parameters. t According to this method, by adjusting the centrifugal oscillation speed W in real time t This method achieves the consistency of the concentration rate.

[0104] It should be understood that those skilled in the art can make improvements or changes based on the above description, and all these improvements and changes should fall within the scope of protection of the appended claims of the present invention.

Claims

1. A vacuum quantitative concentration device, characterized in that: include: A concentration cup, used for containing the sample solution, wherein a tail tube is provided at the lower end of the concentration cup; A vacuum module is used to evacuate the air inside the concentration cup so as to form a vacuum above the sample solution in the concentration cup; An oscillating module oscillates the concentration cup to accelerate the flow of the sample solution inside the concentration cup; A water bath heating module is used to heat the middle part of the concentration cup in a water bath, so that the impurity solution contained in the sample solution in the concentration cup is evaporated by heat, thereby concentrating the sample solution; Waste gas recovery module, used to collect impurity solution evaporated by heat; A condensation reflux module condenses and cools the upper part of the concentration cup, so that the target solution carried by the evaporated impurity solution vapor is cooled, condensed and refluxed to the concentration cup; A low temperature anti-evaporation module is used to keep the tail tube located at the bottom of the concentration cup at a low temperature to prevent the sample solution in the concentration cup from being completely evaporated; The control module is used to coordinate the vacuum module, the oscillation module, the water bath heating module, the waste gas recovery module, the reflux module and the low-temperature anti-evaporation module to achieve concentration of the sample solution in the concentration cup.

2. The vacuum quantitative concentration equipment according to claim 1, characterized in that: The vacuum quantitative concentration device also includes: The fixed cover is used for fixing the concentrated cup and has a heating element inside.

3. The vacuum quantitative concentration device according to claim 2, characterized in that: The concentrate cups are provided in plurality and are all arranged on the bottom surface of the fixed cover; The fixed cover is provided with a channel corresponding to the concentration cup for allowing evaporated impurity solution steam and vacuumed air to pass through.

4. The vacuum quantitative concentration equipment according to claim 1, characterized in that: The water bath heating module is a water heating box, and the lower end of the concentration cup passes through the bottom of the water heating box.

5. The vacuum quantitative concentration equipment according to claim 1, characterized in that: A heat insulating member is provided between the low-temperature evaporation prevention module and the water bath heating module. The low-temperature evaporation prevention module includes a base. A receiving groove and a low-temperature circulating water channel are provided on the base corresponding to the tail pipe. The low-temperature evaporation prevention module also includes a water circulating pipe group arranged corresponding to the low-temperature circulating water channel.

6. A concentration method of a vacuum quantitative concentration device, according to any one of claims 1 to 5, characterized in that: The method comprises the following steps: The inner cavity of the concentration cup is divided into a constant diameter area and a variable diameter area from top to bottom, wherein the variable diameter area is a truncated cone transition section connecting the concentration cup and the tail pipe; Determining whether the liquid surface of the sample solution in the concentration cup is located in the constant diameter zone or the variable diameter zone; When the liquid level of the sample solution is located in the constant diameter zone, executing the first concentration method to make the concentration rate of the sample solution constant; When the liquid level of the sample solution is located in the diameter-changing region, the second concentration method is performed to make the concentration rate of the sample solution constant.

7. The concentrating method of the vacuum quantitative concentrating device according to claim 6, characterized in that: The method further comprises: When the first concentration method is executed, in order to reduce the influence of condensation reflux on the concentration rate during the period of executing the first concentration method, a third concentration method is further executed to achieve rate influence compensation.

8. The vacuum quantitative concentration device and concentration method according to claim 7, characterized in that: The third concentration method is: The centrifugal oscillation rotation angular velocity W of the concentration cup is kept constant, and as the liquid level drops, the vacuum degree P above the liquid level is adjusted in real time according to a vacuum preset rule, wherein the vacuum preset rule is P=P0(1-Δh)t; Among them, △h is the height that the liquid level drops per unit time, P0 is the initial vacuum degree above the liquid level, and t is the concentration time.

9. The vacuum quantitative concentration device and concentration method according to claim 8 or 6, characterized in that: The first concentration method comprises: maintaining the centrifugal oscillation rotation angular velocity W of the concentration cup constant, and maintaining the temperature T and vacuum degree P of the constant diameter zone constant.

10. The vacuum quantitative concentration device and concentration method according to claim 8 or 6, characterized in that: The second concentration method is: Keep the internal vacuum degree P of the concentration cup constant, and adjust the centrifugal oscillation rotation angular velocity W of the sample solution in real time according to the preset oscillation rules. t , the preset oscillation rule is f(w t , r t ) = kf(w0, r1); in: k is the reference coefficient, which can be obtained through multiple experiments; is the calculation formula for the vortex surface area formed by the rotation of the sample solution surface, is a formula for expressing the vortex surface formed by the rotation of the sample solution liquid surface, g is the gravitational acceleration, R is the centrifugal oscillation rotation radius of the concentration cup, and r is the static liquid surface radius; W0 is the initial centrifugal oscillation rotation angular velocity, r1 is the radius of the constant diameter zone, r t To adjust the radius of the circular surface formed by the liquid surface in the diameter-changing area in real time; The r t By the identity V 初 -V 蒸发 =V 剩余 Solved, among which, V 初 is the initial volume of the sample solution, is a constant, is the volume of the remaining solution, V 蒸发 is the volume that has evaporated easily, according to the formula V 蒸发 =t×V 速 get, V 速 is the target concentration rate, is the preset constant, t is the time of real-time adjustment, and t1 is the time when the liquid surface of the sample solution is completely located in the diameter-changing area; h t To adjust the height of the liquid level in real time and through the formula Obtained, α is the angle between the inclined surface and the bottom surface of the truncated cone transition section.

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