A sampling needle device with a preheating function

Abstract

A sampling needle device with a preheating function, comprising: a sampling needle, including a needle tip at the lower end, a needle tail at the upper end, and a rod portion in the middle; a heating sleeve, wrapped around the outside of the sampling needle; a heat-insulating and insulating sleeve, wrapped around the outer side of the heating sleeve; an outer sleeve, wrapped around the outer side of the heat-insulating and insulating sleeve, and the outer sleeve is made of conductive metal; a heating plate, arranged at the upper end of the sampling needle, and the heating sleeve penetrates through the heating plate; a heater, arranged at the top of the heating plate; a wiring thread sleeve, arranged at the upper end of the sampling needle and electrically connected to the heating sleeve. A heating device is designed on the sampling needle, and by controlling the heated surface of the sampling needle in different regions, the sampling needle is heated evenly in the entire length direction; the heating system has temperature control and over-temperature protection functions; it has a good heat preservation effect; a metal wrapping is added to the outermost layer, which can greatly improve the sensitivity and accuracy of liquid level detection.

Description

Technical Field

[0001] This application belongs to the technical field of medical devices, and particularly relates to a sampling needle device with a preheating function. Background Art

[0002] During the testing process of chemiluminescence immunoassay equipment, samples and reagents need to react fully in an environment of 37 ± 0.5 °C, so that the antigen or antibody to be detected can be fully captured. Reagents need to be refrigerated, generally controlled at 2 - 8 °C. The temperature of most samples is around 20 °C, and the amount of reagent is much larger than that of the sample. Currently, most equipment places the reaction vessels (reaction cups) in a incubation tray and adds samples and reagents into the reaction cups for heating through a sampling needle. The heating path is: the heater heats the incubation tray body, the incubation tray body heats the air inside the tray, the air heats the reaction cup, and the reaction cup then heats the samples and reagents. The rate of heat transfer is low, resulting in a long time for the samples and reagents to reach 37 °C, generally taking 5 - 10 minutes. On the one hand, it will affect the reaction degree between the samples and reagents; on the other hand, it will prolong the time to obtain the test results.

[0003] This application proposes a sampling needle loader with a preheating function, and a heating device is designed on the sampling needle. The function of the sampling needle is to aspirate a certain amount of sample or reagent and add it into the reaction vessel. Within a few seconds between sample aspiration and sample discharge, the reagent or sample can be quickly heated up to reach or approach 37 °C, so that when the reagent or sample cup is added into the reaction cup, it can quickly reach 37 ± 0.5 °C. Summary of the Invention

[0004] The technical problem to be solved by this invention is that the rate of heat transfer is low, resulting in a long time for the samples and reagents to reach 37 °C. To solve the deficiency of slow heating rate in the prior art, a sampling needle device with a preheating function is provided.

[0005] The technical solution adopted by this invention to solve its technical problems is: a sampling needle device with a preheating function, comprising:

[0006] A sampling needle, including a tip at the lower end, a needle tail at the upper end, and a rod portion in the middle, for aspirating a certain amount of sample or reagent and adding it into the reaction vessel;

[0007] A heating sleeve, wrapped around the outside of the sampling needle;

[0008] A heat-insulating and insulating sleeve, wrapped around the outer side of the heating sleeve;

[0009] An outer sleeve, wrapped around the outer side of the heat-insulating and insulating sleeve, and the outer sleeve is made of conductive metal;

[0010] The heating plate is arranged at the upper end of the sampling needle, and the heating sleeve penetrates through the heating plate;

[0011] The heater is arranged on the top of the heating plate, and the heater is used to heat the heating plate;

[0012] The wiring thread sleeve is arranged at the upper end of the sampling needle and is conductively connected to the outer sleeve.

[0013] Preferably, in a sampling needle device with a preheating function according to the present invention, a heat preservation upper cover is arranged on the top of the heater.

[0014] Preferably, in a sampling needle device with a preheating function according to the present invention, a heat preservation lower cover is arranged on the bottom surface of the heating plate.

[0015] Preferably, in a sampling needle device with a preheating function according to the present invention, a temperature sensor and a temperature switch are installed on the heating plate, and the temperature sensor is used to detect the temperature of the heating plate.

[0016] Preferably, in a sampling needle device with a preheating function according to the present invention, a wiring thread hole is arranged on the side wall of the outer sleeve.

[0017] Preferably, in a sampling needle device with a preheating function according to the present invention, a first temperature equalizing groove is arranged on the outer side wall of the upper end of the heating sleeve.

[0018] Preferably, in a sampling needle device with a preheating function according to the present invention, a second temperature equalizing groove is arranged on the outer side wall of the middle part of the heating sleeve, and the length and width dimensions of the second temperature equalizing groove are smaller than those of the first temperature equalizing groove.

[0019] Preferably, in a sampling needle device with a preheating function according to the present invention, the outer side wall of the lower end of the heating sleeve is set as a smooth cylindrical surface.

[0020] Preferably, in a sampling needle device with a preheating function according to the present invention, a first potting adhesive is arranged at the lower ports of the heating sleeve, the heat insulation and insulation sleeve, and the outer sleeve.

[0021] Preferably, in a sampling needle device with a preheating function according to the present invention, a second potting adhesive is arranged at the upper ports of the heat insulation and insulation sleeve and the outer sleeve, and the second potting adhesive isolates the heating plate from the heat insulation and insulation sleeve and the outer sleeve.

[0022] The beneficial effects of the present invention are as follows: A heating device is designed on the sampling needle. Since the inner cavity of the sampling needle is in direct contact with the liquid (sample or reagent), the temperature rise of the liquid is fast;

[0023] A variety of sizes of temperature equalizing grooves are arranged on the heating sleeve. By controlling the heated surface of the sampling needle in different regions, the sampling needle is heated evenly in the entire length direction;

[0024] By installing a temperature sensor and a temperature switch on the heating plate, the heating system has temperature control and over-temperature protection functions;

[0025] The setting of the upper and lower heat preservation covers and the heat insulation and insulating sleeves makes the device have a good heat preservation effect;

[0026] Adding a metal wrap on the outermost layer of the device can greatly improve the sensitivity and accuracy of liquid level detection. Brief Description of the Drawings

[0027] The technical solutions of the present application will be further described below in conjunction with the drawings and embodiments.

[0028] Figure 1 It is a schematic diagram of the overall structure of the embodiment of the present application;

[0029] Figure 2 It is a schematic diagram of the internal structure of the embodiment of the present application and an enlarged view;

[0030] Figure 3 It is a schematic diagram of the temperature equalizing structure of the heating sleeve of the embodiment of the present application.

[0031] The reference numerals in the drawings are:

[0032] 1: Sampling needle, 101: Needle tip, 102: Needle tail;

[0033] 2: Heating sleeve, 201: First temperature equalizing groove, 202: Second temperature equalizing groove;

[0034] 3: Heat insulation and insulating sleeve;

[0035] 4: Outer sleeve, 401: Wiring threaded hole;

[0036] 5: First potting compound;

[0037] 6: Second potting compound;

[0038] 7: Upper heat preservation cover;

[0039] 8: Lower heat preservation cover;

[0040] 9: Heating plate;

[0041] 10: Temperature sensor;

[0042] 11: Temperature switch;

[0043] 12: Heater;

[0044] 13: Wiring threaded sleeve. Detailed Description of the Embodiment

[0045] It should be noted that, without conflict, the embodiments in the present application and the features in the embodiments may be combined with each other.

[0046] In the description of the present application, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as limiting the protection scope of the present application. In addition, the terms "first", "second", etc. are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined with "first", "second", etc. may explicitly or implicitly include one or more of such features. In the description of the present invention, unless otherwise stated, the meaning of "a plurality" is two or more.

[0047] In the description of the present application, it should be noted that unless otherwise clearly defined and limited, the terms "installed", "connected", "connected" should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood through specific situations.

[0048] The technical solutions of the present application will be described in detail below with reference to the drawings and in combination with the embodiments.

[0049] Embodiment

[0050] This embodiment provides a sampling needle device with a preheating function. Refer to Figure 1 , including:

[0051] The sampling needle 1 includes a needle tip 101 at the lower end, a needle tail 102 at the upper end, and a rod portion in the middle.

[0052] The sampling needle 1 is set as a long tubular shape, used to suck a certain amount of liquid sample or reagent and discharge it into the reaction cup. When sucking liquid, the needle tip 101 directly enters below the liquid level of the reagent tube for sampling, and the needle end 102 is connected to the pump valve pipeline. To avoid the reaction between the sampling needle 1 and the sample or reagent, 316L stainless steel material is generally selected.

[0053] Refer to Figure 2, the heating sleeve 2 is wrapped around the outer side of the rod part arranged in the middle of the sampling needle 1. The heating sleeve 2 is made of a material with good heat conduction performance, generally pure copper material. The heating sleeve 2 and the sampling needle 1 are joined together with silver brazing filler metal by argon arc welding. The welding structure has high strength and good heat conductivity at the welding point. The heating sleeve 2 conducts heat to the sampling needle 1 to perform a heating operation on the sampling needle 1. An insulating sleeve 3 is wrapped around the outer side of the heating sleeve 2, and an outer sleeve 4 is wrapped around the outer side of the insulating sleeve 3. The outer sleeve 4 plays a protective role, and the insulating sleeve 3 is used for heat preservation, so that as much heat as possible on the heating sleeve 2 is conducted to the sampling needle 1. At the same time, the heat insulation function of the insulating sleeve 3 isolates the outer sleeve 4 from the heating sleeve 2, preventing it from being scalding. The lower ports of the heating sleeve 2, the insulating sleeve 3, and the outer sleeve 4 and the upper ports of the insulating sleeve 3 and the outer sleeve 4 are all sealed with glue. The second potting glue 6 at the upper end isolates the heating plate 9 from the insulating sleeve 3 and the outer sleeve 4, playing a role of insulation and heat insulation. The potting glue needs to be selected with good insulation and high bonding strength, such as epoxy resin glue.

[0054] Preferably, for a sampling needle device with a preheating function in this embodiment, a heating plate 9 is arranged at the upper end of the sampling needle 1, and the sampling needle 1 and the heating sleeve 2 penetrate through the heating plate 9. A heater 12 is installed above the heating plate 9. The heater 12 is of the thin-film resistor type, with an adhesive on the surface, small in volume and convenient to install, and has a large power density. During operation, the heater 12 heats the heating plate 9, the heating plate 9 transfers the heat to the heating sleeve 2, and the heating sleeve 2 then heats the sampling needle 1. When the sampling needle 1 aspirates a sample or reagent, it will heat the liquid in the cavity through the inner wall. Since the contact area between the inner wall of the cavity of the sampling needle 1 and the liquid is large, and the aspirated liquid volume is relatively small, generally the maximum liquid volume is about 100 uL, the entire temperature rise process of the liquid is relatively fast.

[0055] Preferably, for a sampling needle device with a preheating function in this embodiment, a wiring threaded sleeve 13 is arranged at the upper end of the sampling needle 1 and is welded to the heating needle 1 with good conduction. The wiring threaded sleeve 13 is connected to one end of the liquid level detection wire. A wiring threaded hole 401 is arranged on the side wall of the outer sleeve 4 and is welded to the outer sleeve 4 with good conduction, and is connected to the other end, the shielded grounding end of the liquid level detection. The capacitance values at both ends are detected to determine whether the tip of the needle touches the liquid surface. In this embodiment, the outer sleeve 4 wraps around the periphery of the sampling needle 1, which can improve the sensitivity during small liquid volume detection, thereby reducing the dead volume of sampling.

[0056] Preferably, for a sampling needle device with a preheating function in this embodiment, a heat preservation upper cover 7 and a heat preservation lower cover 8 are installed above and below the heating plate 9 respectively to play a role in heat preservation for the entire heating system.

[0057] Preferably, in a sampling needle device with a preheating function according to this embodiment, a temperature sensor 10 and a temperature switch 11 are installed on the heating plate 9. The temperature sensor 10 can monitor the temperature of the heating plate 9. When the temperature exceeds the set value, the heater stops working or reduces its power; when the temperature is lower than the set value, the heater 12 works or increases its power to generate heat. When the entire temperature control system fails, for example, if the heater 12 continuously works and causes the temperature of the heating plate 9 to be too high, the temperature switch 11 will act to stop the heater 12 from working.

[0058] Referring to Figure 3 , preferably, in a sampling needle device with a preheating function according to this embodiment, a first temperature equalizing groove 201 is provided on the outer side wall of the upper end portion (area a) of the heating sleeve 2, and a second temperature equalizing groove 202 is provided on the outer side wall of the middle portion (area b) of the heating sleeve 2. In this embodiment, the first temperature equalizing groove 201 and the second temperature equalizing groove 202 are provided in the shape of kidney holes. The outer side wall of the lower end portion (area c) of the heating sleeve 2 is provided as a smooth cylindrical surface. The length and width dimensions of the second temperature equalizing groove 202 are smaller than those of the first temperature equalizing groove 201. Since the upper region of the heating sleeve 2 is close to the heating plate 9, the temperature will be slightly higher. The temperature of the entire heating sleeve 2 is distributed in a gradient from top to bottom. To reduce the non-uniformity of liquid heating, some temperature equalizing grooves are opened in the region with a higher temperature of the heating sleeve to reduce the contact heating area between the heating sleeve and the sampling needle. The first temperature equalizing groove 201 in the upper region is larger and denser, the second temperature equalizing groove 202 in the middle region is the second, and no temperature equalizing groove is opened in the bottom region. In this way, the temperature of the sampling needle can be more evenly distributed, so that the liquid in the sampling needle cavity is heated evenly.

[0059] Inspired by the above ideal embodiments based on this application, through the above description, relevant staff can completely make various changes and modifications without departing from the technical idea of this application. The technical scope of this application is not limited to the content in the specification, and its technical scope must be determined according to the scope of the claims.

Claims

1. A sampling needle device with a preheating function, characterized in that, Comprising: A sample adding needle (1), including a needle tip (101) at the lower end, a needle tail (102) at the upper end, and a rod portion in the middle, for sucking a certain amount of sample or reagent and adding it into a reaction container; a heating sleeve (2), wrapped and arranged on the outer side of the sample adding needle (1); a heat insulation and insulation sleeve (3), wrapped and arranged on the outer side surface of the heating sleeve (2); an outer sleeve (4), wrapped and arranged on the outer side surface of the heat insulation and insulation sleeve (3), and the outer sleeve (4) is made of conductive metal; a heating plate (9), the heating plate (9) is arranged at the upper end of the sample adding needle (1) and is connected to the heating sleeve (2); a heater (12), arranged on the top of the heating plate (9), and the heater (12) is used for heating the heating plate (9); a wiring threaded sleeve (13), arranged at the upper end of the sample adding needle (1) and is conductively connected to the outer sleeve (4); a first temperature equalizing groove (201) is arranged on the outer side wall of the upper end of the heating sleeve (2); a second temperature equalizing groove (202) is arranged on the outer side wall of the middle of the heating sleeve (2), and the length and width dimensions of the second temperature equalizing groove (202) are smaller than the length and width dimensions of the first temperature equalizing groove (201); the outer side wall of the lower end of the heating sleeve (2) is set as a smooth cylindrical surface.

2. The sampling needle device with a preheating function according to claim 1, characterized in that, A heat preservation upper cover (7) is arranged on the top of the heater (12).

3. The sample adding needle device with a preheating function according to claim 2, characterized in that, A heat preservation lower cover (8) is arranged on the bottom surface of the heating plate (9).

4. The sampling needle device with a preheating function according to claim 3, characterized in that, A temperature sensor (10) and a temperature switch (11) are installed on the heating plate (9), and the temperature sensor (10) is used for detecting the temperature of the heating plate (9).

5. A sample adding needle device with a preheating function according to claim 1, characterized in that, A wiring threaded hole (401) is arranged on the side wall of the outer sleeve (4).

6. The sampling needle device with a preheating function according to claim 2, characterized in that, A first potting adhesive (5) is arranged at the lower ports of the heating sleeve (2), the heat insulation and insulation sleeve (3), and the outer sleeve (4).

7. The pipetting needle device with a preheating function according to claim 6, characterized in that, A second potting adhesive (6) is arranged at the upper ports of the heat insulation and insulation sleeve (3) and the outer sleeve (4), and the second potting adhesive (6) isolates the heating plate (9) from the heat insulation and insulation sleeve (3) and the outer sleeve (4).

Images