Valve clipping system

Abstract

The present invention provides a valve clamping system, comprising a clamping device and a conveying device. The clamping device comprises a connecting member, at least two clamp arms, and a drive assembly connecting the at least two clamp arms. The drive assembly is used to drive the at least two clamp arms to open or close relative to the connecting member. The connecting member is provided with a first through hole along the axial direction. The conveying device comprises a push shaft, a core shaft, and at least one locking member. The push shaft is provided with a second through hole along the axial direction. The distal end of the push shaft is plugged into the proximal end of the connecting member, the second through hole is connected to the first through hole, and the core shaft is movably inserted into the first through hole and the second through hole and is detachably connected to the drive assembly. At least one locking member is connected to the connecting member, and the at least one locking member is tightened toward the proximal end so that the connecting member remains connected to the push shaft. In this valve clamping system, the connection between the connecting member and the push shaft is stable, and the matching accuracy requirements for the core shaft and the connection position are low, ensuring that the clamping device and the conveying device can be smoothly released.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical devices, and in particular relates to a valve clamping system. Background Art

[0002] Insufficient regurgitation of heart valves, such as the mitral and tricuspid valves, can cause blood to flow backward from the ventricles into the atria. A minimally invasive procedure currently available uses the principle of edge-to-edge valve repair. A clipping device is delivered to the mitral or tricuspid valve via a delivery device. The clipping device is then manipulated to clamp the two leaflets, thereby partially securing the leaflets in position and reducing mitral or tricuspid regurgitation.

[0003] Please also refer to Figure 1 and Figure 2 In the prior art, the connecting tube 31 of the clamping device 30 and the push tube 41 of the conveying device 40 are detachably connected via a block-and-slot connection or a circular snap-fit connection. A mandrel is inserted through the push tube 41 and the connecting tube 31 to push the inwardly offset block at the distal end of the push tube 41 outward, causing it to engage the slot in the connecting tube 31 or to support the circular snap-fit position of the connecting tube 31 and the push tube 41. When the mandrel is withdrawn from the connection point 50 between the push tube 41 and the connecting tube 31, the connection between the push tube 41 and the connecting tube 31 is released. The existing connection method between the push tube 41 and the connecting tube 31 has high requirements on the matching accuracy between the core shaft and the connecting position 50. If the matching clearance is too tight, the core shaft will be subjected to excessive friction generated by the connecting position 50 during the withdrawal process, which may easily cause the core shaft to bend or break; if the matching clearance is too large, the connection between the push tube 41 and the connecting tube 31 will be unstable, and the connecting position 50 will easily tilt or offset, which will not only affect the movement of the core shaft, but also make it difficult for the clamping device 30 and the conveying device 40 to be smoothly released. Summary of the Invention

[0004] The technical problem to be solved by the present invention is to provide a valve clamping system in response to the defects of the existing technology. The connection method between the clamping device and the conveying device in the valve clamping system can not only ensure that the clamping device and the conveying device in the valve clamping system maintain a stable connection when connected, but also ensure that the clamping device and the conveying device can be smoothly released after being disconnected.

[0005] In order to solve the above technical problems, the present invention provides a valve clamping system, including a clamping device and a conveying device. The clamping device includes a connecting member, at least two clamp arms and a drive assembly connecting the at least two clamp arms. The drive assembly is used to drive the at least two clamp arms to open or close relative to the connecting member. The connecting member is provided with a first through hole along the axial direction. The conveying device includes a push shaft, a core shaft and at least one locking member. The push shaft is provided with a second through hole along the axial direction. The distal end of the push shaft is plugged into the proximal end of the connecting member, the second through hole is connected to the first through hole, the core shaft can be movably inserted into the first through hole and the second through hole and is detachably connected to the drive assembly; at least one locking member is connected to the connecting member, and at least one locking member is tightened toward the proximal end so that the connecting member remains connected to the push shaft.

[0006] The valve clamping system provided by the present invention utilizes a plug-in connection method for the push shaft and the connector. By tightening the locking member, the connector and the push shaft maintain a stable connection; when the locking member is loosened, the connector and the push shaft can be disconnected. This avoids the prior art method of using a core shaft to support the connection point between the push shaft and the connector to achieve the connection between the two. The requirements for the matching precision between the core shaft and the connection point are low, and the core shaft will neither bend or break, nor be affected in its movement. Furthermore, the connection point is prevented from tilting or offsetting, ensuring that the clamping device and the delivery device can be smoothly released. BRIEF DESCRIPTION OF THE DRAWINGS

[0007] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for use in the implementation. Obviously, the drawings described below are some implementations of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0008] Figure 1 It is a three-dimensional structural schematic diagram of the clamping device and the conveying device connected by the clamping block and the clamping slot provided by the prior art during the disconnection process.

[0009] Figure 2 It is a three-dimensional structural schematic diagram of a clamping device and a conveying device connected by arc buckling provided by the prior art during the disconnection process.

[0010] Figure 3 It is a schematic diagram of the three-dimensional structure of the valve clamping system provided by the first embodiment of the present invention when it is in a connected state.

[0011] Figure 4 yes Figure 3 A cross-sectional view of the push shaft, connecting piece, core shaft and drive shaft along the axial direction.

[0012] Figure 5 yes Figure 4 A cross-sectional view of the push shaft along the axial direction.

[0013] Figure 6 yes Figure 5 Schematic diagram of the three-dimensional structure of the middle docking piece.

[0014] Figure 7 yes Figure 6 Cross-sectional view of the middle docking piece along the radial direction.

[0015] Figure 8 yes Figure 4 A cross-sectional view of the middle connecting piece along the axial direction.

[0016] Figure 9 yes Figure 3 Schematic diagram of the three-dimensional structure of the connecting parts.

[0017] Figure 10 yes Figure 3 A schematic diagram of the three-dimensional structure of one of the matching modes of the push shaft, the connecting member and the locking member.

[0018] Figure 11 yes Figure 3 A schematic diagram of the three-dimensional structure of another matching method of the push shaft, connecting piece and locking piece.

[0019] Figure 12 yes Figure 3 Schematic diagram of the three-dimensional structure of the clamping device.

[0020] Figure 13 yes Figure 12 Schematic diagram of the three-dimensional structure after the middle base and connecting parts are assembled.

[0021] Figure 14 yes Figure 13 Schematic diagram of the three-dimensional structure of the middle base.

[0022] Figure 15 yes Figure 13 Side view of the center base.

[0023] Figure 16 yes Figure 13 Cross-sectional view of the middle base along line XVI-XVI.

[0024] Figure 17 yes Figure 13 Cross-sectional view along line XVII-XVII.

[0025] Figure 18 yes Figure 12 Schematic diagram of the three-dimensional structure after the middle base and the gripping part are assembled.

[0026] Figure 19 yes Figure 18 Side view of the assembled mid-base and gripper.

[0027] Figure 20 yes Figure 19 Enlarged view of the XX part.

[0028] Figure 21 yes Figure 3 A cross-sectional view of the middle connector, base, core shaft, and drive shaft when in coordinated use.

[0029] Figure 22 yes Figure 3 Side view of the mid-valve clipping system.

[0030] Figure 23 yes Figure 22 Magnified view of section XXIII.

[0031] Figure 24 This is a schematic diagram of the valve clamping system provided by the first embodiment of the present invention in use.

[0032] Figure 25 yes Figure 24 Magnified view of section XXV.

[0033] Figure 26 It is a schematic diagram of the three-dimensional structure of the connecting component of the valve clamping system provided in the second embodiment of the present invention.

[0034] Figure 27 yes Figure 26 A cross-sectional view of the middle connecting member and the locking member in the mating state.

[0035] Figure 28 3D is a schematic diagram of the three-dimensional structure of the connecting component of the valve clamping system provided in the third embodiment of the present invention.

[0036] Figure 29 yes Figure 28 A cross-sectional view of the first connecting portion of the middle connecting member.

[0037] Figure 30 It is a schematic diagram of the three-dimensional structure of the docking piece of the valve clamping system provided in the third embodiment of the present invention.

[0038] Figure 31 yes Figure 30 Cross-sectional view of the second connecting portion of the middle docking piece.

[0039] Figure 32 It is a schematic diagram of the three-dimensional structure of the valve clamping system provided by the fourth embodiment of the present invention.

[0040] Figure 33 yes Figure 32 A side view of the valve clamping system with the control and unlocking members omitted.

[0041] Figure 34It is a schematic diagram of the three-dimensional structure of the valve clamping system provided in the fifth embodiment of the present invention.

[0042] Figure 35 yes Figure 34 A schematic diagram of the three-dimensional structure after one of the clamp arms is assembled with a sliding member and a driving member.

[0043] Figure 36 yes Figure 35 Schematic diagram of the three-dimensional structure of the sliding part.

[0044] Figure 37 yes Figure 34 Side view of the clamping device in the closed state.

[0045] Figure 38 yes Figure 34 A cross-sectional view of the middle drive member, base, liner and mandrel in one of the usage states.

[0046] Figure 39 yes Figure 34 A cross-sectional view of the middle drive member, base, liner and core shaft in another usage state. DETAILED DESCRIPTION

[0047] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0048] In addition, the following descriptions of the embodiments refer to the accompanying drawings to illustrate specific embodiments in which the present invention may be implemented. Directional terms used in the present invention, such as "upper," "lower," "front," "back," "left," "right," "inner," "outer," and "side," are used solely with reference to the directions in the accompanying drawings. Therefore, the use of directional terms is intended to better and more clearly illustrate and understand the present invention, and is not intended to indicate or imply that the device or component referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limiting the present invention.

[0049] Definition of Direction: For clarity, the end closest to the operator during surgery will be referred to as the "proximal end," and the end farther from the operator will be referred to as the "distal end." Axial refers to the direction parallel to the line connecting the distal and proximal centers of the medical device; radial refers to the direction perpendicular to the axial direction. The above definitions are for convenience only and are not to be construed as limitations on the present invention. "Connection between component A and component B" means that component A is directly connected to component B, or that component A is indirectly connected to component B through another component.

[0050] First embodiment

[0051] See also Figure 3 The first embodiment of the present invention provides a valve clamping system 100 that can be used for edge-to-edge repair of the mitral valve or tricuspid valve to treat mitral valve regurgitation or tricuspid valve regurgitation. The following describes in detail the use of the valve clamping system 100 for edge-to-edge repair of the mitral valve as an example. The valve clamping system 100 includes a clamping device 10 and a delivery device 20. The clamping device 10 and the delivery device 20 are detachably connected. The delivery device 20 can push the clamping device 10 into the heart via a catheter or perform transapical intervention into the heart. In this embodiment, the clamping device 10 is pushed into the heart via a catheter. The proximal end of the clamping device 10 is releasably connected to the delivery device 20. The operator pushes the clamping device 10 to the patient's mitral valve, and then remotely operates the clamping device 10 through an external control handle (not shown) to clamp the two leaflets of the mitral valve together. When the leaflets of the mitral valve are aligned edge to edge, the operator can release the connection between the delivery device 20 and the clamping device 10, so that the clamping device 10 can be detached from the delivery device 20 and remain in the patient's body as an implant to keep the leaflets in the aligned position together, forming a double-hole structure and reducing the patient's mitral valve regurgitation.

[0052] Please also refer to Figures 3 to 5 The clamping device 10 includes a connecting member 11, at least two clamp arms 12 and a driving assembly 13 connecting the at least two clamp arms. The driving assembly 13 is used to drive the at least two clamp arms 12 to open or close relative to the connecting member 11. The connecting member 11 is provided with a first through hole 111 along the axial direction. The conveying device 20 includes a pushing shaft 21, a core shaft 22 and at least one locking member 23. The pushing shaft 21 is provided with a second through hole 211 along the axial direction. The distal end of the pushing shaft 21 is plugged into the proximal end of the connecting member 11, the second through hole 211 is connected to the first through hole 111, and the core shaft 22 can be movably inserted into the first through hole 111 and the second through hole 211 and is detachably connected to the driving assembly 13. At least one locking member 23 is connected to the connecting member 11, and at least one locking member 23 is tightened toward the proximal end so that the connecting member 11 remains connected to the pushing shaft 21.

[0053] In the valve clamping system 100, the push shaft 21 and the connector 11 are connected by a plug-in connection. By tightening the locking member 23, the connector 11 and the push shaft 21 maintain a stable connection; when the locking member 23 is loosened, the connector 11 and the push shaft 21 can be disconnected. This avoids the prior art practice of using a core shaft 22 to support the connection point between the push shaft 21 and the connector 11 to achieve the connection between the two. The requirement for the matching precision between the core shaft 22 and the connection point is low, and the core shaft 22 will neither bend or break, nor be affected in its movement. Furthermore, this prevents tilting or offsetting of the connection point, ensuring smooth disengagement of the clamping device 10 and the delivery device 20.

[0054] It can be understood that the tensioning force required to maintain a stable connection between the push shaft 21 and the connector 11 is provided by the locking member 23. The connection between the push shaft 21 and the connector 11 is safe, stable, and controllable throughout the surgical procedure. The connection or release between the clamping device 10 and the conveying device 20 can be achieved by simply tightening or loosening the locking member 23, which is simple to operate and convenient for surgery. In addition, compared to the prior art, the tensioning force provided by the locking member 23 between the connector 11 and the push shaft 21 avoids the need to support the push shaft 21 and the connector 11 with the support of the core shaft 22. That is, the connection between the push shaft 21 and the connector 11 does not need to rely on the support of the core shaft 22. Therefore, the connection position between the push shaft 21 and the connector 11 will neither cause the core shaft 22 to bend or break, nor affect the movement of the core shaft 22, ensuring the stability of the push-pull operation and release operation of the core shaft 22 in the first through hole 111 and the second through hole 211. It also reduces the strength requirements of the core shaft 22, which is beneficial to process production. The first and second through-holes 111, 211 have equal diameters, facilitating movement of the mandrel 22 within the first and second through-holes 111, 211. Furthermore, the push shaft 21 and connector 11 utilize a plug-in connection. When the locking member 23 is released, the distal end of the push shaft 21 and the proximal end of the connector 11 can be disengaged. Compared to the prior art, this prevents the clamping device 10 from becoming tilted or offset at the connection point between the clamping device 10 and the conveying device 20, preventing it from being released. The clamping device 10 can be both stably connected to the conveying device 20 and quickly released.

[0055] Preferably, the entire valve clipping system 100 is made of biocompatible materials, including but not limited to stainless steel, pure titanium, nickel-titanium, cobalt-chromium alloy, etc., to ensure the safety of the valve clipping system 100 during surgery and after the clipping device 10 is implanted in the human body. Furthermore, an active drug can be applied to the inner surface of the forceps arm 12 that contacts the valve leaflets to promote the growth and adhesion of endothelial cells on the inner surface of the forceps arm 12.

[0056] Please also refer to Figures 4 to 9The connector 11 includes a main body 112 and a first docking portion 113 provided at the proximal end of the main body 112. The push shaft 21 includes a shaft tube 212 and a docking member 213 provided at the distal end of the shaft tube 212. The distal end of the docking member 213 is provided with a second docking portion 2131, which is engaged and plugged into the first docking portion 113. In this way, the distal end of the push shaft 21 can be plugged into the proximal end of the connector 11 by engaging and plugging the second docking portion 2131 of the docking member 213 with the first docking portion 113 of the connector 11.

[0057] In this embodiment, the outer diameter of the shaft tube 212 is larger than the outer diameter of the docking piece 213. The larger outer diameter of the shaft tube 212 facilitates pushing, and the smaller outer diameter of the docking piece 213 allows the outer diameter of the connector 11 plugged into the docking piece 213 to be smaller, thereby reducing the overall size of the clamping device 10. The docking piece 213 and the shaft tube 212 are fixedly connected by methods including but not limited to welding, gluing, welding, etc. It should be noted that the second through hole 211 passes through the shaft tube 212 and the docking piece 213. In a modified embodiment, the outer diameter of the shaft tube 212 can be equal to the outer diameter of the docking piece 213, and the docking piece 213 can also be integrally formed with the shaft tube 212. Optionally, the docking piece 213 can be made of a biocompatible material such as a polymer material PEEK (Polyetheretherketone), nickel-titanium alloy, stainless steel, or cobalt-chromium alloy to ensure the safety of the operation. Preferably, the docking piece 213 is made of stainless steel.

[0058] One of the first docking portion 113 and the second docking portion 2131 is a docking hole opened in the axial direction, and the other is a docking sleeve extending in the axial direction. When the push shaft 21 is connected to the connector 11, the docking sleeve is inserted into the docking hole, and the axis of the docking sleeve is collinear with the axis of the docking hole. In this way, the second docking portion 2131 can be connected to the first docking portion 113 by inserting the docking sleeve into the docking hole, that is, the docking piece 213 of the push shaft 21 is coaxially plugged with the connector 11, thereby realizing the connection between the push shaft 21 and the connector 11. When the push shaft 21 is connected to the connector 11, that is, when the docking piece 213 is plugged with the connector 11, the axis of the docking sleeve is collinear with the axis of the docking hole, which is conducive to the core shaft 22 passing through the connection position of the docking piece 213 and the connector 11, facilitating the smooth movement of the core shaft 22.

[0059] In this embodiment, the first docking portion 113 is a docking sleeve extending axially from the proximal end of the connector 11, and the second docking portion 2131 is a docking hole opened axially from the distal end of the connector 213. When the push shaft 21 is connected to the connector 11, the first docking portion 113 (docking sleeve) is inserted into the second docking portion 2131 (docking hole). It should be noted that the diameter of the docking hole is larger than the diameter of the second through hole 211, so that the docking sleeve can be inserted into the docking hole while ensuring that the diameter of the first through hole 111 is equal to the diameter of the second through hole 211. In addition, the main body 112 of the connector 11 is columnar, and the outer diameter of the main body 112 is larger than the outer diameter of the docking sleeve, that is, the main body 112 forms a step at the connection with the first docking portion 113, and the step acts as a limiter when the docking sleeve is inserted into the docking hole. Specifically, during the process of plugging the docking piece 213 into the connector 11, the docking sleeve is inserted into the docking hole and continuously moves axially until the step presses against the distal surface of the docking piece 213. In a modified embodiment, the first docking portion 113 can be a docking hole opened axially in the connector 11, and the second docking portion 2131 can be a docking sleeve extending axially from the distal end of the docking piece 213. When the docking piece 213 is connected to the connector 11, the solution of the second docking portion 2131 (docking sleeve) being inserted into the first docking portion 113 (docking hole) is also within the scope of protection of the present invention. The docking hole can be obtained by machining, electric discharge machining, or die casting.

[0060] Please also refer to Figure 6 and Figure 9 The first docking portion 113 is provided with at least one first anti-rotation surface 1131, and the second docking portion 2131 is provided with a second anti-rotation surface 2132 that fits in place with the first anti-rotation surface 1131. Thus, when the first docking portion 113 is mated with the second docking portion 2131, the cooperation between the first anti-rotation surface 1131 and the second anti-rotation surface 2132 ensures anti-rotation stability in the connection between the first docking portion 113 and the second docking portion 2131. Even under external forces, the connection will not deflect, thus avoiding angular deviation during instrument operation and ensuring operational accuracy.

[0061] In this embodiment, the outer wall of the first docking portion 113 (dock tube) is provided with two axially symmetrical first anti-rotation surfaces 1131, and the inner wall of the second docking portion 2131 (dock hole) is provided with a second anti-rotation surface 2132 that mates with the two first anti-rotation surfaces 1131 one-to-one. Both the first anti-rotation surfaces 1131 and the second anti-rotation surfaces 2132 are planes formed by cutting along the axial direction, that is, both the first anti-rotation surfaces 1131 and the second anti-rotation surfaces 2132 are parallel to the axial direction. When the first docking portion 113 is fitted onto the second docking portion 2131, the two first anti-rotation surfaces 1131 mate with the two second anti-rotation surfaces 2132 one-to-one along the axial direction. Under the action of external force, the two axially symmetrical first anti-rotation surfaces 1131 and the two one-to-one mate second anti-rotation surfaces 2132 provide a uniformly distributed anti-rotation force, preventing deflection of the first docking portion 113 and the second docking portion 2131. In an alternative embodiment, the two first anti-rotation surfaces 1131 may be asymmetrically arranged, and correspondingly, the two second anti-rotation surfaces 2132 may be modified accordingly. In an alternative embodiment, the number of first anti-rotation surfaces 1131 and corresponding second anti-rotation surfaces 2132 may be 1, 3, 4, or other positive integers that are at least 1.

[0062] The first docking portion 113 is provided with at least one first coaxial surface 1132, and the second docking portion 2131 is provided with a second coaxial surface 2133 that fits in place with the first coaxial surface 1132. Thus, when the first docking portion 113 is mated with the second docking portion 2131, the first coaxial surface 1132 and the second coaxial surface 2133 cooperate to ensure coaxial stability between the first docking portion 113 and the second docking portion 2131. This ensures coaxiality during operation and release of the clamping device 10, ensuring smooth operation and release.

[0063] In this embodiment, the outer wall of the first docking portion 113 (docking tube) is provided with two axially symmetrical first coaxial surfaces 1132. These first coaxial surfaces 1132 are respectively connected to the two first anti-rotation surfaces 1131. Specifically, each first coaxial surface 1132 is located between the two first anti-rotation surfaces 1131, and the two first coaxial surfaces 1132 are spaced apart. The inner wall of the second docking portion 2131 (docking hole) is provided with second coaxial surfaces 2133 that mate with the two first coaxial surfaces 1132 in a one-to-one manner. Both the first coaxial surfaces 1132 and the second coaxial surfaces 2133 are arcuate surfaces. When the first docking portion 113 is inserted into the second docking portion 213, the two first coaxial surfaces 1132 mate with the two second coaxial surfaces 2133 in a one-to-one correspondence. Consequently, the arcuate mating of the first and second docking portions 113, 213 improves the coaxial fit precision, facilitating operation and release of the clamping device 10. In an alternative embodiment, the two first coaxial surfaces 1132 may be asymmetrically arranged, and correspondingly, the two second coaxial surfaces 2133 may also be changed accordingly. In an alternative embodiment, the number of the first coaxial surfaces 1132 and the corresponding second coaxial surfaces 2133 may be 1, 3, 4, or other positive integers that are at least 1.

[0064] Please also refer to Figures 8 to 10 The connector 11 further includes at least one connecting portion 114 provided on the main body 112, and at least one locking member 23 can be pulled or released to connect to the at least one connecting portion 114. Thus, when the connector 11 is plugged into the docking member 213, the locking member 23 can be pulled proximally to transmit a tensioning force (i.e., a connecting force) to the connector 11 via the connecting portion 114, causing the connector 11 to tend to move proximally and press against the docking member 213. Therefore, by keeping the locking member 23 pulled, a stable connection between the connector 11 and the docking member 213 can be maintained; and by releasing the locking member 23, the docking member 213 of the push shaft 21 can be separated from the connector 11, thereby quickly releasing the clamping device 10 from the conveying device 20.

[0065] Specifically, the connecting portion 114 is a hook protruding from the main body 112, and the locking member 23 is a wire, string, or rope. The locking member 23 is hooked by the hook and connected to the connecting portion 114. The connecting portion 114 being a hook facilitates connecting and removing the locking member 23, while the locking member 23 being a wire, string, or rope facilitates pulling. It should be noted that one end of the hook is connected to the main body 112, and the other end is directed toward the distal end of the main body 112. Therefore, pulling the locking member 23 toward the proximal end stabilizes the connection between the connector 11 and the docking member 213.

[0066] In this embodiment, there are two connecting parts 114, and the two connecting parts 114 are symmetrically arranged relative to the axis of the main body 112. There are two locking members 23, and the two locking members 23 are connected to the two connecting parts 114 in a one-to-one correspondence. After each locking member 23 is hooked by the corresponding connecting part 114 in a U shape, both ends extend toward the proximal end to the outside of the human body. At this time, the operator can maintain the connection between the connecting member 11 and the docking member 213 by tightening the two ends of each locking member 23 toward the proximal end and keeping the tightened state. When the locking member 23 is loosened, the connection between the connecting member 11 and the docking member 213 can be released. In addition, when it is no longer necessary to tighten the locking member 23, the locking member 23 can be removed by pulling one end of each locking member 23, which is simple to operate.

[0067] In the implementation of the change, please refer to Figure 11 , the number of locking members 23 can also be one, and the locking member 23 is U-shaped and hooked on the two connecting parts 114, with both ends extending proximally to the outside of the human body. Its operation process is similar to that described above and will not be repeated here. In a modified embodiment, the number of locking members 23 can be 3, 4, 5 or other positive integers that are at least 1. In a modified embodiment, the two connecting parts 114 can also be asymmetrically arranged. In a modified embodiment, the number of connecting parts 114 can be 1, 3, 4 or other positive integers that are at least 1. Optionally, the locking member 23 is one of a single-strand nickel-titanium wire, a multi-strand nickel-titanium wire or a suture. Preferably, the locking member 23 is a suture.

[0068] Also, please see Figure 9 and Figure 12 The projection of the connecting portion 114 perpendicular to the axial direction intersects with the projection of the caliper arm 12 perpendicular to the axial direction. That is, the plane in which the connecting portion 114 lies along the axial direction intersects with the plane in which the caliper arm 12 lies along the axial direction. In this way, the presence of the connecting portion 114 does not interfere with the opening and closing of the caliper arm 12 relative to the connecting member 11. Preferably, the projection of the connecting portion 114 perpendicular to the axial direction is perpendicular to the projection of the caliper arm 12 perpendicular to the axial direction.

[0069] Please also refer to Figure 9 and Figures 12 to 17The clamping device 10 also includes a base 14, which is connected to the connecting member 11, and at least two clamp arms 12 are rotatably connected to the base 14. Specifically, the main body 112 is cylindrical, and the distal end of the main body 112 is provided with a first interlocking portion 115, and the proximal end of the base 14 is provided with a second interlocking portion 1422. One of the first interlocking portion 115 and the second interlocking portion 1422 is an interlocking hole opened in the axial direction, and the other is an interlocking tube extending in the axial direction, and the interlocking tube is installed in the interlocking hole. When the interlocking tube is installed in the interlocking hole, the connecting member 11 is connected to the base 14. In this way, the at least two clamp arms 12 can be opened or closed by rotating relative to the base 14, thereby achieving the opening or closing of the at least two clamp arms 12 relative to the connecting member 11.

[0070] In this embodiment, there are two pliers arms 12. The base 14 includes a frame portion 141 and a rotating portion 142 protruding from the proximal end of the frame portion 141. Each pliers arm 12 is rotatably connected to the rotating portion 142 on both sides via two spaced-apart rotating shafts 143. Specifically, the frame portion 141 includes two first support walls 1411 disposed opposite each other and two second support walls 1412 connected to the two first support walls 1411 and disposed opposite each other. The first support walls 1411 are parallel to the radial direction, and the second support walls 1412 are parallel to the axial direction. The two first support walls 1411 and the two second support walls 1412 surround and form a accommodating space 1413. The rotating portion 142 protrudes from the first support wall 1411 near the proximal end of the frame portion 141. Each clamp arm 12 includes a clamping piece 121 for clamping the leaflet and two opposing connecting pieces 122. The two connecting pieces 122 are fixedly connected to opposite sides of the clamping piece 121. Each connecting piece 122 has a through-hole (not shown) extending through the distal end. The rotating portion 142 has a radially extending through-hole 1421. Each rotating shaft 143 passes through the through-hole of the connecting piece 122 on one side of each clamp arm 12 and is installed in the through-hole 1421. The connecting pieces 122 on both sides of each clamp arm 12 are rotatably connected to the rotating portion 142 via the two rotating shafts 143. In other words, each clamp arm 12 is rotatably connected to the base 14 about the two rotating shafts 143, thereby allowing the two clamp arms 12 to rotate relative to the base 14 to open or close. In alternative embodiments, the number of clamp arms 12 can be 3, 4, 5, or other positive integers of at least 2. Preferably, the clamping piece 121 is provided with a plurality of process holes 1211 to reduce the overall mass of the clamp arm 12 and facilitate the crawling of endothelial cells after the clamping device 10 is implanted into the human body.

[0071] In this embodiment, the first interlocking portion 115 is an interlocking tube, and the second interlocking portion 1422 is an interlocking hole. The interlocking hole is provided in the rotating portion 142, axially extending through the rotating portion 142 and connecting the through hole 1421 and the accommodating space 1413. The interlocking tube is welded into the interlocking hole, so that the connector 11 is fixedly connected to the proximal end of the base 14. Thus, the opening or closing of the two clamp arms 12 relative to the base 14 is equivalent to the opening or closing of the two clamp arms 12 relative to the connector 11. Moreover, when the connector 11 is connected to the base 14 via the above-described connection method, the axis of the interlocking hole is collinear with the axis of the first through hole 111 of the connector 11, greatly improving the concentricity of the base 14 and the connector 11, ensuring the smoothness and stability of the operation of the clamping device 10. It should be noted that the outer diameter of the interlocking tube is smaller than the outer diameter of the main body 112. In this way, the length of the interlocking cylinder can be limited during the insertion of the interlocking hole, thereby ensuring the accuracy of the assembly dimensions. In a modified embodiment, the interlocking cylinder can also be inserted into the interlocking hole by threaded connection or gluing to achieve a fixed connection between the connector 11 and the base 14. In a modified embodiment, the rotating portion 142 is provided with an interlocking cylinder extending axially toward the proximal end, the distal end of the main body 112 is provided with an interlocking hole axially, and the interlocking cylinder is fitted into the interlocking hole, so that the connector 11 is fixedly connected to the proximal end of the base 14. This solution is also within the scope of protection of the present invention.

[0072] Please also refer to Figure 12 and Figures 18 to 20 The clamping device 10 further includes a gripping member 15 disposed between the base 14 and the clamp arm 12. The gripping member 15 includes a fixing portion 151 and at least two gripping arms 152 connected to the fixing portion 151. The fixing portion 151 is fixedly connected to the base 14. The gripping arms 152 have an elastic memory function and cooperate with the clamp arm 12 to grasp the leaflets. In this way, the gripping arms 152 and the clamp arm 12 jointly grasp and clamp the leaflets, providing good stability and facilitating the clamping of the leaflets.

[0073] The gripping member 15 is secured to the base 14 by a snap-fit mechanism. The securing portion 151 is heat-set to form an inverted, inward-facing structure. In this embodiment, the securing portion 151 is provided with a receiving groove 1511, into which the frame portion 141 of the base 14 is positioned. The securing portion 151 secures the frame portion 141 of the base 14, preventing relative movement between the gripping member 15 and the base 14 after they are engaged, thereby facilitating a stable connection between the gripping member 15 and the base 14.

[0074] For details, please refer to Figure 12 、 Figure 14 、 Figure 15 、 Figure 19 and Figure 20The fixing portion 151 includes a first snap-fit position 1512 and a second snap-fit position 1513. When the frame portion 141 is fixed in the receiving groove 1511, the first snap-fit position 1512 and the second snap-fit position 1513 can limit the relative movement of the gripping member 15 and the base 14 in the axial and radial directions of the clamping device 10 after they are mated and connected. Specifically, the connection between the first support wall 1411 of the frame portion 141 and the rotating portion 142 is a smooth first arc surface 1415, and the connection between the first support wall 1411 and the second support wall 1412 is a smooth second arc surface 1416. The first snap-fit position 1512 is a curved piece that fits correspondingly with the first arc surface 1415, and the second snap-fit position 1513 is a curved piece that fits correspondingly with the second arc surface 1416. Among them, the curvature radius K11 of the first snap-fit position 1512 is greater than the curvature radius K21 of the first arc surface 1415, and the curvature radius K12 of the second snap-fit position 1513 is smaller than the curvature radius K22 of the second arc surface 1416. Therefore, when the frame body 141 is fixed in the accommodating groove 1511, a first avoidance position 1514 is retained between the first arc surface 1415 and the first snap-fit position 1512, and a second avoidance position 1515 is retained between the second arc surface 1416 and the second snap-fit position 1513. The contact point between the fixing portion 151 and the frame body 141 is set between the first avoidance position 1514 and the second avoidance position 1515, so as to avoid interference in the connection between the fixing portion 151 and the frame body 141 and ensure the stability of the first snap-fit position 1512.

[0075] Also, please see Figure 14 and Figure 18 The fixing portion 151 may be provided with a limiting hole 1516 radially extending through the receiving groove 1511. The frame portion 141 may be provided with a limiting member 1414 protruding radially outward from each of the two second support walls 1412. When the frame portion 141 is placed in the receiving groove 1511, the limiting member 1414 engages with the limiting hole 1516, further limiting relative movement between the gripping member 15 and the base 14.

[0076] Further, please also refer to Figure 3 and Figure 18 The delivery device 20 also includes a control member 24 for controlling the movement of the grasping arms 152 away from or toward the forceps arm 12. Each grasping arm 152 is provided with at least one control hole 1521 at one end away from the fixing portion 151, and the control member 24 is connected to the control hole 1521. Thus, the operator can control the opening and closing of the grasping arms 152 by operating the control member 24, facilitating the grasping arms 152 to cooperate with the forceps arm 12 to grasp the valve leaflets. It should be noted that the control member 24 can extend from the grasping arms 152 to the patient's body to facilitate surgical operations.

[0077] In this embodiment, there are two grasping arms 152, each corresponding one-to-one with each clamp arm 12. There are also two control members 24, each connected one-to-one with each grasping arm 152. Specifically, the control members 24 are filamentary. Each control member 24 passes through the control hole 1521 of its corresponding grasping arm 152, with both ends extending toward the proximal end of the delivery device 10 and out of the human body. Pulling each control member 24 proximally causes each grasping arm 152 to rotate relative to the fixing portion 151 toward the base 14, thereby moving the grasping arm 152 away from the clamp arm 12. At this point, a space exists between each grasping arm 152 and its corresponding clamp arm 12, allowing the valve leaflet to enter between them. When force is removed from the control members 24, each grasping arm 152 rebounds due to its inherent elastic memory function. At this time, the grasping arm 152 moves toward the direction close to the clamp arm 12, and the leaflet can be pressed into the clamp arm 12. When the clamping device 10 is in the conveying state, the grasping arm 152 of the grasping member 15 is tightened by the control member 24 in a closed state and is close to the outer wall of the connecting member 11 connected to the base 14. In a modified embodiment, the number of grasping arms 152 can also be 3, 4 or other numbers greater than 2. Generally, the number of grasping arms 152 should be consistent with the number of clamp arms 12. In a modified embodiment, the number of control members 24 can also be 1, 3, 4, 5 or other positive integers that are at least 1. Optionally, the control member 24 is one of a single-strand nickel-titanium wire, a multi-strand nickel-titanium wire or a suture. Preferably, the control member 24 is a single-strand nickel-titanium wire.

[0078] Each grasping arm 152 may be provided with at least one process hole (not shown) to reduce the overall mass of the grasping arm 152. This not only helps to improve the elasticity of the grasping arm 152, but also facilitates the crawling of endothelial cells after the clamping device 10 is implanted in the human body. Each grasping arm 152 may also be provided with a coating material covering the edge of the grasping arm 152 to prevent damage to the leaflets during clamping.

[0079] Please also refer to Figure 12 and Figure 21 The drive assembly 13 includes a drive shaft 131 and a transmission member 132 connected to the drive shaft 131. The drive shaft 131 is axially movable and extends through the base 14 and the connector 11, and is detachably connected to the core shaft 22. The transmission member 132 is connected to at least two forceps arms 12. Thus, the core shaft 22 can be operated to drive the drive shaft 131 to move axially within the base 14 and the connector 11, thereby driving the at least two forceps arms 12 to rotate relative to the base 14 via the transmission member 132, thereby opening or closing the two forceps arms 12. The operator can open and close the two forceps arms 12 by moving the core shaft 22, facilitating surgical operations.

[0080] Specifically, in this embodiment, there are two caliper arms 12. The transmission member 132 includes a base 1321 and two connecting arms 1322 disposed on opposite sides of the base 1321. The two connecting arms 1322 are connected one-to-one with the two caliper arms 12. One end of each connecting arm 1322 is rotatably connected to the base 1321 via a connecting shaft, and the other end is rotatably connected to the caliper arm 12 via a connecting shaft, thereby rotatably connecting the transmission member 132 to the two caliper arms 12. The frame portion 141 of the base 14 is axially defined with a through hole 1417 extending through a first support wall 1411 of the frame portion 141 and communicating with the accommodating space 1413. The base 1321 is axially defined with a fixing hole 1323. The distal end of the drive shaft 131 is received in the fixing hole 1323 by methods including, but not limited to, welding or gluing, thereby securely connecting the drive shaft 131 to the base 1321. The proximal end of the drive shaft 131 passes through the through hole 1417 of the base 14 and the accommodating space 1413 in sequence and is placed in the first through hole 111 of the connecting member 11. At this time, the drive shaft 131 is driven to move axially, causing the connecting arm 1322 to rotate and drive the two clamp arms 12 to open or close relative to the connecting member 11.

[0081] In addition, the core shaft 22 can be detachably connected to the drive shaft 131 by means of a threaded connection. Specifically, the proximal end of the drive shaft 131 is provided with an external thread 1311, and the distal end of the core shaft 22 is provided with an internal thread 221 that matches the above-mentioned external thread 1311. When the distal end of the push shaft 21 is connected to the connector 11 through the docking piece 24, the distal end of the core shaft 22 can be sequentially inserted into the push shaft 21 and the connector 11 and threadedly connected to the proximal end of the drive shaft 131, so that pushing and pulling the core shaft 22 along the axial direction can drive the drive shaft 131 to move axially, thereby driving the two clamp arms 12 to open or close relative to the connector 11, thereby facilitating surgical operations. In a modified embodiment, the proximal end of the drive shaft 131 is provided with an internal thread, and the distal end of the core shaft 22 is provided with a matching external thread, so that the core shaft 22 is connected to the drive shaft 131. This is also within the scope of protection of the present invention.

[0082] Please also read Figure 12 、 Figure 22 and Figure 23, a positioning portion 1312 is provided on the outer circumference of the drive shaft 131. The clamping device 10 also includes a locking assembly, which is used to lock the drive shaft 131 to limit the axial movement of the drive shaft 131. The locking assembly includes a locking member 16 and a push member 1418. The locking member 16 is provided with a locking hole (not shown) along the axial direction. The drive shaft 131 is inserted into the locking hole. The push member 1418 pushes against the locking member 161 and is tilted in the frame portion 141 of the base 14, so that the edge of the locking hole can be snapped into the positioning portion 1312, so that the drive shaft 131 and the base 14 are relatively fixed, thereby limiting the opening and closing of the clamp arm 12; by pulling the locking member 16, the edge of the locking hole and the drive shaft 131 move relative to each other. At this time, the locking member 16 applies pressure to the push member 1418, causing the push member 1418 to bend and deform, so that the drive shaft 131 can move axially relative to the locking member 16. Loosening the locking member 16 can lock the drive shaft 131 again.

[0083] The locking assembly also includes an operating member 17 connected to the locking member 16. The operating member 17 is used to pull the locking member 16 to release the locking member 16 from locking the drive shaft 131. In this embodiment, the operating member 17 is unilaterally unlocked, which means that the operating member 17 is connected to a single side of the locking member 16. Specifically, the operating member 17 is connected to one end of the locking member 16. Pulling the operating member 17 toward the proximal end causes the locking member 16 to release the lock on the drive shaft 131, allowing the drive shaft 131 to move axially. When the pulling force on the operating member 17 is released, the locking member 16 resumes its lock on the drive shaft 131, so that the drive shaft 131 is fixed relative to the base 14 and the drive shaft 131 cannot move axially.

[0084] To facilitate remote control of the operating member 17 outside the body, the delivery device 20 also includes an unlocking member 25 connected to the operating member 17. The unlocking member 25 can be a wire, string, or rope. The unlocking member 25 is detachably connected to the operating member 17, with both ends extending proximally outside the body. The unlocking member 25 is typically made of a polymer material. Before the clamping device 10 is released, the unlocking member 25 is connected to the operating member 17. When the unlocking member 25 is tightened, the operating member 17 releases the locking member 16 from the drive shaft 131, and the clamping device 10 enters the unlocked state; otherwise, the clamping device 10 enters the self-locking state.

[0085] Please also refer to Figure 4 and Figure 24 and Figure 25 The following uses a transcatheter cardiac interventional mitral valve 1 edge-to-edge repair surgery as an example to illustrate the use and working principle of the valve clipping system 100 provided in the first embodiment of the present invention:

[0086] S1. Connect the docking piece 213 at the distal end of the pushing shaft 21 with the proximal end of the connecting piece 11, lift the locking piece 23 and keep it in a tensioned state so that the docking piece 213 and the connecting piece 11 remain connected; push the core shaft 22 between the pushing shaft 21 and the connecting piece 11 and rotate the core shaft 22 so that the core shaft 22 is screwed to the drive shaft 131.

[0087] S2. The delivery device 20 and the clamping device 10 connected thereto are pushed into the left atrium 2 through a guiding device such as an adjustable sheath (not shown), and then pass through the mitral valve 1 to reach the left ventricle 3. The clamping device 10 is adjusted to be close to the anterior leaflet 1a and the posterior leaflet 1b of the mitral valve 1.

[0088] S3. Pull the unlocking piece 25 to release the lock on the driving shaft 131 by the locking piece 16, operate the core shaft 22 and the control piece 24, when the anterior leaflet 1a and the posterior leaflet 1b of the mitral valve 1 are respectively clamped between the clamp arm 12 and the grasping arm 152, pull the core shaft 22 proximally to drive the two clamp arms 12 to close, so that the clamping device 10 clamps the leaflets; release the unlocking piece 25, the driving shaft 131 is locked, and the clamping device 10 maintains the state of clamping the leaflets.

[0089] S4. Rotate the core shaft 22 to separate the core shaft 22 from the drive shaft 131, withdraw and remove the core shaft 22; loosen the locking piece 23, withdraw and remove the pushing shaft 21, the unlocking piece 25, the control piece 24, and the locking piece 23, so that the conveying device 20 is disengaged from the clamping device 10, so that the clamping device 10 that clamps the leaflet remains at the mitral valve 1.

[0090] During the operations of S1 , S2 and S3 , the locking member 23 is always kept in a tensioned state to maintain the connection between the pushing shaft 21 of the conveying device 20 and the connecting member 11 of the clamping device 10 .

[0091] Second embodiment

[0092] Please also refer to Figure 8 、 Figure 9 、 Figure 26 and Figure 27 Compared to the valve clipping system 100 provided in the first embodiment, the valve clipping system provided in the second embodiment of the present invention has a different structure for the connecting member 11b. Other structures remain unchanged and will not be further described here. In the second embodiment, the connecting portion 114b of the connecting member 11b is a lug protruding from the main body 112b. The lug is provided with a through-hole 1141b. The locking member 23b is a wire, thread, or rope that passes through the through-hole 1141b to connect to the connecting portion 114b. This ensures that the locking member 23b passes through the through-hole 1141b of the lug, thereby ensuring the stability of the locking member 23b during installation and operation, and preventing the locking member 23b from slipping off the connecting portion 114b.

[0093] Third embodiment

[0094] Please also refer to Figures 26 to 31 Compared to the valve clamping system provided in the second embodiment, the valve clamping system provided in the third embodiment of the present invention has different structures in the connector 11c and the docking member 213c of the push shaft, while other structures remain unchanged and will not be described in detail here. Similar to the second embodiment, in the third embodiment, one of the first docking portion 113c of the connector 11c and the second docking portion 2131c of the docking member 213c is a docking hole opened along the axial direction, and the other is a docking tube extending along the axial direction. The inner wall surface of the docking hole and the outer wall surface of the docking tube are both inclined relative to the axial direction. In this way, the first docking portion 113c of the connector 11c and the second docking portion 2131c of the docking member 213c both have a certain taper, which can further improve the smoothness of release and further prevent the first docking portion 113c and the second docking portion 2131c from deflecting or getting stuck at the docking position, thereby preventing smooth release.

[0095] Taking the first docking portion 113c as a docking sleeve and the second docking portion 2131c as a docking hole as an example, the outer wall surface of the first docking portion 113c (docking sleeve) is inclined inwardly toward the proximal end relative to the axial direction, and the inner wall surface of the second docking portion 2131c (docking hole) is inclined inwardly toward the proximal end relative to the axial direction. Specifically, an angle A1 is formed between the outer wall surface of the first docking portion 113c of the connector 11c and the inner wall surface of the first through hole 111c of the connector 11c, i.e., the angle between the outer wall surface of the first docking portion 113c and the axial direction is A1; an angle A2 is formed between the inner wall surface of the second docking portion 2131c of the connector 24c and the outer wall surface of the connector 213c, i.e., the angle between the inner wall surface of the second docking portion 213c and the axial direction is A2. The angle A1 is equal to the angle A2, so that the first docking portion 113c and the second docking portion 213c can adaptively match when docked, improving the concentricity of the two, and facilitating the smoothness and stability of the surgical operation.

[0096] Optionally, the angles A1 and A2 are in the range of 0° to 10°. Preferably, the angles A1 and A2 are in the range of 2° to 5°. The other structures of the connecting member 11c and the docking member 213c are similar to those of the second embodiment and will not be described in detail.

[0097] Fourth embodiment

[0098] Please also refer to Figure 3 、 Figure 32 and Figure 33Compared to the valve clipping system 100 provided in the first embodiment, the valve clipping system 100d of the fourth embodiment of the present invention features a different structure in the connector 11d. The remaining structures remain unchanged and will not be further described here. Furthermore, the valve clipping system 100d of the fourth embodiment also undergoes a different surgical approach. In this embodiment, the clipping device 10d is delivered into the heart via a transapical approach.

[0099] In the fourth embodiment, a frame-shaped attachment portion 115d is provided at the distal end of the main body 112d of the connector 11d. The attachment portion 115d is connected to the distal end of the base 14d at its proximal end. Specifically, the attachment portion 115d includes a first connecting wall 1151d and a second connecting wall 1152d disposed opposite each other, and two third connecting walls 1153d disposed opposite each other and connecting the first and second connecting walls 1151d and 1152d. The first connecting wall 1151d and the second connecting wall 1152d are both parallel to the radial direction, while the two third connecting walls 1153d are both parallel to the axial direction. The first connecting wall 1151d is located closer to the distal end of the valve clipping system 100d than the second connecting wall 1152d. The second connecting wall 1152d is connected to the distal end of the main body 112d. The first connecting wall 1151d is fixedly connected to the proximal end of the base 14d by welding. The projection of the attachment portion 115d perpendicular to the axial direction intersects the projection of the distal clamp arm 12d, which is rotatably connected to the base 14d. Specifically, the plane of the attachment portion 115d intersects the plane of the clamp arm 12d, preventing the attachment portion 115d from interfering with the opening and closing of the clamp arm 12d. Preferably, the projection of the attachment portion 115d perpendicular to the axial direction is perpendicular to the projection of the clamp arm 12d perpendicular to the axial direction. When the docking member 213d at the distal end of the push shaft 21d is inserted into the proximal end of the connector 11d, the locking member 23d is tightened toward the proximal end to maintain the connection between the push shaft 21d and the connector 11d. The method of inserting the docking member 213d into the connector 11d is the same as that of the first embodiment and will not be further described. A guide member 19d is axially disposed at the distal end of the base 14d. This guide member 19d communicates with the interior of the base 14d, allowing the drive shaft 131d to axially move through the main body 112d, attachment portion 115d, base 14d, and guide member 19d in sequence. This helps ensure stable axial movement of the drive shaft 131d, ensuring stability during surgical procedures. Furthermore, the control member 24d, connected to the gripping arm 152d of the gripping member 15d, and the unlocking member 25d, connected to the operating member 17d, can both extend outside the patient's body through the guide member 19d, facilitating surgical procedures.

[0100] The valve clipping system 100d provided in this embodiment and the valve clipping system 100 provided in the first embodiment have different surgical pathways, but the usage process and working principles are the same.

[0101] Fifth embodiment

[0102] Please also refer to Figure 3 and Figures 34 to 39 The valve clamping system 100e provided in the fifth embodiment of the present invention is different from the valve clamping system 100 provided in the first embodiment in that the driving method for opening and closing the clamp arm 12e relative to the connecting member 11e and the method for limiting the axial movement of the driving shaft 131e in the fifth embodiment are different from those in the first embodiment.

[0103] For details, please refer to Figure 34 、 Figure 35 and Figure 37 In the fifth embodiment, the drive assembly 13e includes a drive member 131e movably connected to the base 14e and at least two sliders 132e slidably connected to the clamp arms 12e. Each slider 132e is rotationally connected to the drive member 131e. The drive member 131e moves axially relative to the base 14e, driving each slider 132e to slide relative to its corresponding clamp arm 12e, thereby causing the at least two clamp arms 12e to open or close relative to the base 14e. In this way, the opening and closing of the clamp arm 12e is driven by the sliding member 132e. After the clamp arm 12e clamps the leaflet, the force arm L1 of the leaflet tension acting on the clamp arm 12e is the length from the sliding member 132e to the proximal end (free end) of the clamp arm 12e. Since the sliding member 132e slides relative to the clamp arm 12e when the clamp arm 12e is closed, the force arm L1 is shortened, thereby reducing the torque applied to the clamp arm 12e in the clamped state, preventing the clamp arm 12e from fatigue deformation due to long-term leaflet tension, and ensuring that the clamping device 10e can provide a stable clamping force, thereby maintaining a better clamping effect.

[0104] Please also refer to Figures 34 to 37In this embodiment, the number of clamp arms 12e is two, and the number of sliding members 132e slidably connected to the clamp arms 12e is also two. Similar to the first embodiment, the connecting member 11e includes a main body 112e and a first docking portion 113e provided at the proximal end of the main body 112e. The main body 112e is cylindrical, and the distal end of the main body 112e is fixedly engaged with the proximal end of the base 14e. The driving member 131e includes a driving shaft 1311e and two transmission rods 1312e fixedly connected to the driving shaft 1311e and provided on the circumference of the driving shaft 1311e. The driving shaft 1311e is axially movable and passes through the base 14e and the connecting member 11e. The two transmission rods 1312e rotatably connect the two sliding members 132e in a one-to-one correspondence. The distal end of the connecting piece 122e of each clamp arm 12e is rotatably connected to the base 14e via two rotating shafts 133e. The specific connection method is described in the first embodiment and will not be repeated here. Thus, when the drive shaft 131e moves axially, the transmission rod 1312e drives the sliding member 132e to slide on the clamp arm 12e, thereby causing the two clamp arms 12e to rotate relative to the base 14e and open and close, that is, the two clamp arms 12e open or close relative to the connecting member 11e.

[0105] The distal end of the clamping piece 121e of each clamp arm 12e is provided with a slide groove 1211e extending toward the center of the clamping piece 121e along its length. The sliding member 132e slides along the length of the corresponding clamp arm 12e in the slide groove 1211e, allowing each sliding member 132e to slide relative to its corresponding clamp arm 12e. Specifically, the sliding member 132e includes a rotating portion 1321e rotatably connected to the transmission rod 1312e and two sliding portions 1322e disposed on either side of the rotating portion 1321e. Each sliding portion 1322e is provided with a sliding groove 1323e. The portions of the clamping piece 121e located on either side of the slide groove 1211e are slidably disposed in the sliding grooves 1323e, thereby slidably connecting the sliding member 132e to the clamp arm 12e. When the drive shaft 1311e moves axially toward the proximal end relative to the base 14e, the drive member 131e drives each slider 132e to slide along the slide groove 1211e toward the proximal end of the corresponding clamp arm 12e. At the same time, under the constraint of the sliding portion 1322e of each slider 132e located on both sides of the slide groove 1323e, the slider 132e drives the corresponding clamp arm 12e to rotate relative to the base 14e in a direction closer to the base 14e, causing the clamp arm 12e to close relative to the base 14e to clamp the valve leaflet. When the drive shaft 1311e moves axially toward the distal end relative to the base 14e, the clamp arm 12e opens relative to the base 14e. The specific process is similar to that described above and will not be repeated here.

[0106] In the valve clamping system 100e of this embodiment, during the process of clamping the valve leaflets, the pulling force of the driver 131e is converted into a clamping force by the clamp arm 12e. The smaller the closing angle of the clamp arm 12e relative to the base 14e, the greater the required clamping force. As the closing angle of the clamp arm 12e relative to the base 14e decreases, the slider 132e moves closer to the middle of the clamp arm 12e, significantly shortening the moment arm L1 exerted by the leaflet pulling force on the clamp arm 12e when the clamp arm 12e is in the closed state. This reduces the torque applied to the clamp arm 12e during the clamping state, preventing fatigue deformation of the clamp arm 12e due to prolonged leaflet pulling force. This effectively improves the deformation resistance of the clamping device 10e, ensuring that the clamping device 10e can still provide a stable clamping force and maintain an optimal clamping effect even under prolonged clamping conditions.

[0107] Please also refer to Figure 34 and Figures 38 to 39 In the fifth embodiment, a resilient engaging portion 1121e is provided on the circumferential wall of the main body 112e of the connecting member 11e. The engaging portion 1121e includes a locking end 1122e, which is tilted toward the interior of the main body 112e. At least one engaging groove 1313e is provided on the outer circumferential surface of the drive shaft 1311e. The locking end 1122e engages with the engaging groove 1313e to restrict the position of the drive shaft 1311e within the base 14e. When the drive shaft 1311e moves axially within the base 14e and the connecting member 11e, causing the clamp arms 12e to clamp the leaflets, the locking end 1122e of the engaging portion 1121e engages with the engaging groove 1313e of the drive shaft 1311e to restrict movement of the drive shaft 1311e, thereby locking the angle between the two clamp arms 12e and enabling the clamp arms 12e to stably clamp the leaflets.

[0108] The delivery device 20e also includes a liner 27e that is sleeved between the push shaft 21e and the core shaft 22e. When the abutment 213e at the distal end of the push shaft 21e is connected to the connector 11e, the liner 27e abuts against the engaging portion 1121e, causing the locking end 1122e of the engaging portion 1121e to deflect toward the exterior of the main body 112e and disengage from the retaining groove 1313e, thereby allowing the drive shaft 1311e to move axially. When the drive shaft 1311e moves axially proximally until the forceps arm 12e engages the valve leaflets, the liner 27e is withdrawn, and the locking end 1122e of the engaging portion 1121e engages the retaining groove 1313e of the drive shaft 1311e, thereby restricting further axial movement of the drive shaft 1311e and maintaining the forceps arm 12e in the position of retaining the valve leaflets. The pulling force of the leaflet on the clamp arm 12e is transmitted to the drive shaft 1311e, causing the drive shaft 1311e to tend to move toward the distal end; at this time, the locking end 1122e of the clamping portion 1121e is subjected to an extrusion force toward the distal end under the action of the clamping groove 1313e of the drive shaft 1311e, causing the locking end 1122e to move closer to the center of the drive shaft 1311e, thereby achieving an effect that the greater the pulling force of the leaflet on the drive shaft 1311e, the tighter the locking portion 1121e and the drive shaft 1311e are locked, ensuring that the clamp arm 12e can stably clamp the leaflet.

[0109] The above is an implementation of the embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the embodiment of the present invention. These improvements and modifications are also considered to be within the scope of protection of the present invention.

Claims

1. A valve clipping system, characterized in that: include: A clamping device, the clamping device comprising a connecting member, at least two clamp arms, and a driving assembly connecting the at least two clamp arms, the driving assembly being used to drive the at least two clamp arms to open or close relative to the connecting member, the connecting member being provided with a first through hole along the axial direction; and A delivery device, comprising a push shaft, a core shaft, and at least one locking member, wherein the push shaft is provided with a second through hole along the axial direction, the distal end of the push shaft is plugged into the proximal end of the connecting member, the second through hole is connected to the first through hole, the core shaft is movably inserted into the first through hole and the second through hole and is detachably connected to the drive assembly, the at least one locking member is connected to the connecting member, and the at least one locking member is tightened toward the proximal end so that the connecting member remains connected to the push shaft; The connecting member includes a main body and a first docking portion provided at the proximal end of the main body, the pushing shaft includes a shaft tube and a docking member provided at the distal end of the shaft tube, the distal end of the docking member is provided with a second docking portion, the second docking portion is engaged and plugged into the first docking portion, and the locking member is located outside the docking member.

2. The valve clipping system according to claim 1, characterized in that: One of the first docking portion and the second docking portion is a docking hole opened along the axial direction, and the other is a docking tube extending along the axial direction; When the pushing shaft is connected to the connecting piece, the docking sleeve is inserted into the docking hole, and the axis of the docking sleeve is collinear with the axis of the docking hole.

3. The valve clipping system according to claim 1 or 2, characterized in that: The first docking portion is provided with at least one first anti-rotation surface, and the second docking portion is provided with a second anti-rotation surface that fits in with the first anti-rotation surface.

4. The valve clipping system according to claim 1 or 2, characterized in that: The first docking portion is provided with at least one first coaxial surface, and the second docking portion is provided with a second coaxial surface that fits in contact with the first coaxial surface.

5. The valve clipping system according to claim 2, characterized in that: The inner wall surface of the docking hole and the outer wall surface of the docking tube are both inclined relative to the axial direction.

6. The valve clipping system according to claim 1, characterized in that: The connecting member further comprises at least one connecting portion provided on the main body, and the at least one locking member can be pulled up or released to connect the at least one connecting portion.

7. The valve clipping system according to claim 6, characterized in that: The connecting portion is a hook protruding from the main body, the locking member is a wire, a thread or a rope, and the locking member is hooked by the hook to connect to the connecting portion.

8. The valve clipping system according to claim 6, characterized in that: The connecting portion is a lug protruding from the main body, the lug is provided with a through hole, the locking member is a wire, a thread or a rope, and the locking member passes through the through hole to connect to the connecting portion.

9. The valve clipping system according to any one of claims 6 to 8, characterized in that: The projection of the connecting portion in a direction perpendicular to the axial direction is staggered with the projection of the clamp arm in a direction perpendicular to the axial direction.

10. The valve clipping system according to claim 1, wherein: The clamping device further includes a base, the base is connected to the connecting member, and the at least two clamp arms are rotatably connected to the base.

11. The valve clipping system according to claim 10, characterized in that: A first engaging portion is provided at the distal end of the main body, and a second engaging portion is provided at the proximal end of the base. One of the first engaging portion and the second engaging portion is an engaging hole opened along the axial direction, and the other is an engaging tube extending along the axial direction. The engaging tube is inserted into the engaging hole.

12. The valve clipping system according to claim 10, wherein: An attachment portion is provided at the distal end of the main body portion, and the attachment portion is frame-shaped. The proximal end of the base is connected to the distal end of the attachment portion.

13. The valve clipping system according to claim 10, wherein: The clamping device also includes a grasping member arranged between the base and the clamp arm, the grasping member includes a fixing portion and at least two grasping arms connected to the fixing portion, the fixing portion is fixedly connected to the base, the grasping arm has an elastic memory function, and the grasping arm cooperates with the clamp arm to grasp the leaflet.

14. The valve clipping system according to claim 10, wherein: The driving assembly includes a driving member movably connected to the base and at least two sliding members slidably connected to the clamp arms in a one-to-one manner. Each of the sliding members is rotationally connected to the driving member. The driving member moves axially relative to the base to drive each sliding member to slide relative to the clamp arm to which it is correspondingly connected, thereby driving the at least two clamp arms to open or close relative to the base.

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