Valve clipping device and valve clipping system

Abstract

The present invention relates to the technical field of medical devices, and provides a valve clamping device and a valve clamping system, wherein the valve clamping device comprises a lock seat, a first clamping member, a second clamping member, a lock core, a control rod and a lock block, wherein one end of the first clamping member is rotatably mounted on the lock seat; one end of the second clamping member is mounted on the lock seat; the middle part of the lock core has a second through hole; the control rod can be movably inserted into the second through hole, and the control rod is used to drive at least two first clamping members to open or close relative to the lock seat; the lock block is configured to move toward the second through hole when abutting against the lock seat to clamp the control rod located in the second through hole. The valve clamping device and the valve clamping system provided by the present invention have the following beneficial effects: the lock core and the lock seat are threadedly matched, so that the lock core and the lock block can be adjusted steplessly and finely, and the lock block abuts against the lock seat to clamp and lock the control rod, thereby solving the technical problems of the valve clamping device in the related art that the unlocking of the valve clamping device by the control line is complicated in operation and has high surgical risks.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a valve clamping device and a valve clamping system. Background Art

[0002] See also Figure 1 This is an anatomical diagram of the heart, where LA stands for left atrium, MV stands for mitral valve, LF stands for valve leaflets, and LV stands for left ventricle. The mitral valve MV is two valve leaflets LF attached to the periphery of the left atrioventricular orifice, connected to the papillary muscle by chordae tendineae, and has the function of preventing the blood in the left ventricle LV from flowing back to the left atrium LA. When the normal heart is supplying blood, the blood enters the left ventricle LV from the left atrium LA through the mitral valve MV, and is then pumped into the aorta by the left ventricle LV to supply the whole body. In the process of heart blood supply, the mitral valve MV acts as a one-way valve, so that blood can only flow from the left atrium LA to the left ventricle LV.

[0003] like Figure 2 As shown in the figure, the two leaflets LF of the mitral valve MV of a normal human body should be well aligned at the end of contraction C. However, the two leaflets LF of the diseased mitral valve MV will not be well aligned at the end of contraction and will cause insufficiency G, as shown in the figure. Figure 3 As shown, reflux occurs.

[0004] When the mitral valve MV is diseased, it will cause mitral valve MV regurgitation, resulting in insufficient blood supply, affecting physical health and quality of life. Mitral valve regurgitation is due to congenital abnormalities or acquired diseases. When the left ventricle LV contracts, it cannot be completely closed, causing part of the blood flowing from the left atrium LA to flow back to the left atrium LA, causing a series of cardiac case changes and clinical symptoms, and in severe cases, it can lead to heart failure.

[0005] Mitral regurgitation is one of the most common valvular diseases today. The main causes include mitral ring dilatation, chordae insufficiency, mitral myxomatous degeneration, leaflet prolapse, rheumatic valvular heart disease, ischemic lesions, etc. Mitral valvuloplasty and artificial valve replacement are the most effective methods for treating mitral regurgitation. However, since the operation requires extracorporeal circulation technology support, it causes great trauma to the human body. For elderly patients and patients with more complications, there are relatively high complications and mortality rates.

[0006] With the development of interventional treatment technology, transcatheter mitral valve repair technology, which has the advantages of less pain, faster recovery, less bleeding, and greatly reduced surgical mortality and postoperative complication rates for patients with contraindications to traditional surgery or high-risk patients, will become the mainstream means of treating mitral regurgitation.

[0007] Therefore, in recent years, medical personnel and researchers in various countries have explored transcatheter mitral valve repair technology. The main interventional treatment methods include annuloplasty, negative pressure suction suture technology and mitral valve clamping. Among them, mitral valve clamping has the most reliable effect. The mitral valve clamp delivers an implantable valve clamping device to the vicinity of the mitral valve through atrial septal puncture, clamps and fixes the free edges of the anterior and posterior leaflets, so that the leaflets are well aligned at the end of contraction and regurgitation is reduced.

[0008] According to the related art known to the inventor, the valve clamping device is provided with a locking structure to prevent the clamp arm from opening again after clamping, but most of the locking structures in the related art lock the movement of the control part by providing a buckle with a concave-convex structure on the clamp arm opening and closing control part, but this buckle-type locking structure has gears and cannot achieve fine adjustment. The locking structure of some valve clamping devices drives the clamp arm opening and closing control part through threaded matching. This threaded locking structure is unlocked by pulling the control line. Since the control line needs to have good flexibility, it is generally a thinner silk line, and the thinner silk line is prone to the risk of breaking during the operation process, resulting in surgical failure or even serious harm to the patient. In addition, after the clamping is completed, the control line needs to be pulled out of the human body. Since the control line is squeezed after the clamp is clamped, the friction force on the control line increases, and when it is removed, the clamp will be deflected and displaced to damage the valve, and even the control line will be broken, stuck and unable to be pulled out of the human body, prolonging the operation time and causing other injuries. Summary of the invention

[0009] The purpose of the present invention is to provide a valve clamping device and a valve clamping system, aiming to solve the technical problems in the related art that the valve clamping device is unlocked by a control line, which has cumbersome operation and high surgical risk.

[0010] To achieve the above-mentioned purpose, the technical solution adopted by the present invention is: a valve clamping device, comprising:

[0011] A lock seat, the lock seat having a first through hole, at least a portion of an inner wall of the first through hole having an internal thread;

[0012] A first clamping member, wherein the number of the first clamping members is at least two, the at least two first clamping members are spaced apart and distributed along the circumference of the lock seat, and one end of the first clamping member is rotatably mounted on the lock seat;

[0013] A second clamping member, the number of the second clamping members is at least two, the at least two second clamping members are spaced apart along the circumference of the lock seat and are located on the inner side of the first clamping member, and one end of the second clamping member is mounted on the lock seat;

[0014] A lock core, wherein the lock core is inserted into the first through hole, at least a portion of the outer wall of the lock core has an outer thread matching the inner thread, and a middle portion of the lock core has a second through hole;

[0015] A control rod, which is movably disposed in the second through hole, is connected to the first clamping member, and is used to drive at least two of the first clamping members to open or close relative to the lock seat;

[0016] A locking block is movably mounted on the lock core, and the locking block is configured to move toward the second through hole when abutting against the lock seat to clamp the control rod located in the second through hole.

[0017] In one embodiment, one end of the locking block is connected to the lock core, and a gap is formed between the other end of the locking block and the lock core. The side wall of the locking block away from the second through hole has a first protrusion, and when the first protrusion abuts against the lock seat, it drives the locking block to move toward the second through hole to clamp the control rod located in the second through hole.

[0018] In one embodiment, the proximal end of the first protrusion has a first slope.

[0019] In one embodiment, the distal end of the first protrusion has a second inclined surface.

[0020] In one embodiment, the lock block and the lock core are integrally formed.

[0021] In one embodiment, the locking block is a hard metal block.

[0022] In one embodiment, a second protrusion is provided on the inner wall of the second through hole close to the locking block.

[0023] In one embodiment, the inner wall of the first through hole has a third inclined surface, and the third inclined surface gradually tilts outward along the direction from the proximal end of the lock seat to the distal end of the lock seat, and the third inclined surface is used to guide the locking block to gradually move toward the second through hole when moving along the direction from the distal end of the lock seat to the proximal end of the lock seat.

[0024] In one embodiment, the inner wall of the first through hole has a fourth inclined surface, and the fourth inclined surface gradually tilts outward along the direction from the distal end of the lock seat to the proximal end of the lock seat, and the fourth inclined surface is used to guide the locking block to gradually move toward the second through hole when moving along the direction from the proximal end of the lock seat to the distal end of the lock seat.

[0025] In one embodiment, the number of the locking blocks is one, two, three, four or five.

[0026] In one embodiment, the number of the locking blocks is more than two, and the more than two locking blocks are spaced apart along the circumference of the lock core.

[0027] In one embodiment, the valve clamping device further comprises a first elastic member, which is mounted on the lock seat and is used to apply elastic force to the lock core to drive the lock core to drive the lock block to move to abut against the lock seat.

[0028] In one embodiment, the lock core is provided with a pushing surface for abutting against the first elastic member.

[0029] In one embodiment, the valve clamping device also includes an unlocking rod and a pull rod, the distal end of the unlocking rod is detachably connected to the proximal end of the lock core, the pull rod is movably inserted into the unlocking rod and the lock core, and the distal end of the pull rod is detachably connected to the proximal end of the control rod.

[0030] In one embodiment, the side of the distal end of the unlocking rod has a first notch, and the proximal end of the lock core has a second notch facing the first notch, the first notch is used to accommodate the proximal end of the lock core, and the second notch is used to accommodate the distal end of the unlocking rod.

[0031] In one embodiment, the pull rod is threadedly connected to the control rod.

[0032] In one embodiment, the valve clamping device also includes a fixing seat and a connecting rod, the distal end of the control rod is fixedly connected to the fixing seat, one end of the connecting rod is rotatably connected to the fixing seat, and the other end of the connecting rod is rotatably connected to the middle part of the first clamping member.

[0033] The present invention also provides a valve clamping system, comprising a proximal handle, a delivery pin tube and the valve clamping device described in any one of the above items, wherein the proximal end of the delivery pin tube is fixedly connected to the distal end of the proximal handle, the distal end of the delivery pin tube is fixedly connected to the locking seat, and the proximal handle is used to operate the valve clamping device.

[0034] The beneficial effects of the valve clamping device and valve clamping system provided by the present invention are as follows: the control rod drives the first clamping member to close relative to the locking seat, the first clamping member and the second clamping member clamp and fix the free edges of the front and rear leaflets, and then the lock core drives the locking block to move in the first through hole until the locking block abuts against the locking seat and moves toward the second through hole at the same time, clamping the control rod located in the second through hole, wherein the lock core and the lock seat are threadedly matched to achieve stepless fine adjustment of the lock core and the locking block, the locking block abuts against the locking seat to clamp and lock the control rod, and the separation of the locking block from the lock seat releases the lock of the control rod, without relying on the control line to unlock, thereby solving the technical problems of the valve clamping device in the related art that is complicated to operate and has high surgical risks by unlocking through the control line, thereby achieving stepless self-locking, and no need to pull out the line after the clamping is completed, thereby reducing the difficulty of operation, shortening the operation time, and improving the success rate of the operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0036] Figure 1 An anatomical structure diagram of a human heart provided by an embodiment of the present invention;

[0037] Figure 2 This is a view of a normal mitral valve;

[0038] Figure 3 This is a view of the regurgitated mitral valve;

[0039] Figure 4 This is a schematic structural diagram of the valve clamping system provided in this embodiment;

[0040] Figure 5 This is a schematic structural diagram of the valve clamping device provided in this embodiment;

[0041] Figure 6 for Figure 5 A schematic diagram of the connection between the lock seat and the lock cylinder;

[0042] Figure 7 for Figure 6 A schematic diagram of the connection between the lock seat and the lock cylinder when the lock block in the lock seat abuts against the lock seat;

[0043] Figure 8 for Figure 7 A schematic diagram of the structure when a first elastic member is installed on the lock seat;

[0044] Fig. 9 for Figure 7 A schematic diagram of the structure when the lock seat is installed with another first elastic member;

[0045] Fig.10 for Figure 5 Another connection diagram of the lock seat and the lock core;

[0046] Fig.11 for Fig.10 A schematic diagram of the structure when a first elastic member is installed on the lock seat;

[0047] Fig.12 for Fig.10 A schematic diagram of the structure when the lock seat is installed with another first elastic member;

[0048] Fig.13 for Figure 5 A schematic diagram of the connection between the lock seat and another lock core;

[0049] Fig.14 for Figure 5 A schematic diagram of the structure of the lock core in FIG.

[0050] Fig.15 for Figure 5 Another structural schematic diagram of the lock core in FIG.

[0051] Fig.16 for Figure 5 A schematic diagram of the connection between the lock seat and another lock core;

[0052] Fig.17 for Figure 5 A schematic diagram of the connection between the lock seat and another lock core;

[0053] Fig.18 for Figure 5 A schematic diagram of the connection between the lock seat and another lock core;

[0054] Fig.19 It is a structural schematic diagram of the valve clamping device when the unlocking rod is connected to the lock core;

[0055] Fig. 20 It is a structural schematic diagram of the valve clamping device when the pull rod and the control rod are separated;

[0056] Fig.21 It is a structural schematic diagram of the valve clamping device when the unlocking rod is connected to the lock core;

[0057] Fig. 22 This is a working state diagram of the valve clamping system;

[0058] Fig.23 is another working state diagram of the valve clamping system;

[0059] Fig.24 This is another working state diagram of the valve clamping system.

[0060] Among them, the reference numerals in the figure are:

[0061] LA, left atrium; LF, valve leaflet; MV, mitral valve; LV, left ventricle;

[0062] 1. Valve clipping system;

[0063] 10. Valve clamping device; 20. Proximal handle; 21. First operating member; 22. Second operating member; 30. Delivery pin tube;

[0064] 100, lock seat; 101, first through hole; 102, internal thread; 103, third inclined surface; 104, fourth inclined surface;

[0065] 210, first clamping member; 220, second clamping member;

[0066] 300, lock core; 301, external thread; 302, second through hole; 303, second protrusion; 304, push surface; 305, second notch;

[0067] 400, control lever;

[0068] 500, locking block; 510, first protrusion; 511, first inclined surface; 512, second inclined surface;

[0069] 610, fixing seat; 620, connecting rod; 630, first elastic member; 640, unlocking rod; 641, first notch; 650, pulling rod; 660, second elastic member; 670, rotating shaft. DETAILED DESCRIPTION

[0070] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0071] In the description of the present invention, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0072] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0073] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0074] In the field of interventional medicine, the end of the instrument closest to the operator is usually defined as the proximal end, and the end farthest from the operator is defined as the distal end.

[0075] The valve clamping device 10 and the valve clamping system 1 in the embodiment of the present invention are now described.

[0076] Please refer to Figure 4 The valve clamping system 1 includes a valve clamping device 10, a proximal handle 20 and a delivery pin tube 30. The proximal end of the delivery pin tube 30 is fixedly connected to the distal end of the proximal handle 20, and the distal end of the delivery pin tube 30 is fixedly connected to the lock seat 100. The proximal handle 20 is used to control the valve clamping device 10.

[0077] Please refer to Figures 5 to 7 The valve clamping device 10 comprises a lock seat 100, a first clamping member 210, a second clamping member 220, a lock core 300, a control rod 400 and a lock block 500. The lock seat 100 has a first through hole 101. At least part of the inner wall of the first through hole 101 has an internal thread 102. The axial direction of the lock seat 100 refers to the direction from the distal end of the lock seat 100 to the proximal end of the lock seat 100, that is, Figure 5 The circumferential direction of the lock base 100 refers to the direction around the axial direction of the lock base 100, that is, Figure 5 In the Y direction.

[0078] The number of the first clamping members 210 is at least two. At least two first clamping members 210 are spaced apart along the circumference of the lock base 100, and one end of the first clamping member 210 is rotatably mounted on the lock base 100. The inner side of the first clamping member 210 refers to the side of the first clamping member 210 close to the lock base 100 in the axial Z direction, and the outer side of the first clamping member 210 refers to the side of the first clamping member 210 away from the lock base 100 in the axial Z direction. The number of the second clamping members 220 is at least two. At least two second clamping members 220 are spaced apart along the circumference of the lock base 100 and are located on the inner side of the first clamping member 210, and one end of the second clamping member 220 is mounted on the lock base 100.

[0079] The lock core 300 is inserted into the first through hole 101. At least part of the outer wall of the lock core 300 has an outer thread 301 matching the inner thread 102. The middle of the lock core 300 has a second through hole 302. The control rod 400 can be movably inserted into the second through hole 302. The control rod 400 is connected to the first clamping member 210. The control rod 400 is used to drive at least two first clamping members 210 to open or close relative to the lock seat 100. The lock block 500 is movably mounted on the lock core 300. The lock block 500 is configured to move toward the second through hole 302 when abutting against the lock seat 100, so as to clamp the control rod 400 located in the second through hole 302.

[0080] When the valve clamping device 10 is used, the control rod 400 drives the first clamping member 210 to close relative to the lock seat 100, that is, the free end of the first clamping member 210 gradually approaches the second clamping member 220, and the first clamping member 210 and the second clamping member 220 can clamp the front and rear leaflets LF (see Figure 1 ) is clamped and fixed by the free edge of the valve closure 101. Then, the lock core 300 drives the lock block 500 to move in the first through hole 101 until the lock block 500 abuts against the lock seat 100 and moves toward the second through hole 302 at the same time, clamping the control rod 400 located in the second through hole 302. The lock core 300 and the lock seat 100 are threadedly matched, which can realize stepless fine adjustment of the lock core 300 and the lock block 500. The lock block 500 abuts against the lock seat 100 and clamps and locks the control rod 400. When the lock block 500 is separated from the lock seat 100, the lock of the control rod 400 is released, and there is no need to rely on the control line to unlock. The technical problems of the valve clamping device 10 in the related art that the unlocking by the control line is complicated and the surgical risk is high, thereby realizing stepless self-locking, and there is no need to pull the line after the clamping is completed, which reduces the difficulty of operation, shortens the operation time, and improves the success rate of the operation.

[0081] The valve clamping device 10 and valve clamping system 1 provided by the present invention are suitable for solving the regurgitation problem caused by mitral and tricuspid valve regurgitation, and are used to capture the leaflets LF in the edge-to-edge repair surgery of the mitral valve MV to achieve the effect of reducing mitral valve regurgitation.

[0082] It should be noted that the number of the first clamping members 210 and the number of the second clamping members 220 may be the same or different. For example, the number of the first clamping members 210 is four, the number of the second clamping members 220 is two, and the control rod 400 drives the four first clamping members 210 to close, and every two first clamping members 210 and one second clamping member 220 jointly clamp one leaflet LF. For another example, the number of the first clamping members 210 is three, the number of the second clamping members 220 is two, and the control rod 400 drives the three first clamping members 210 to close, wherein two first clamping members 210 and one second clamping member 220 jointly clamp one leaflet LF, and another first clamping member 210 and another second clamping member 220 jointly clamp another leaflet LF.

[0083] It should be noted that the installation position of one end of the first clamping member 210 on the lock base 100 and the installation position of one end of the second clamping member 220 on the lock base 100 can be the same (eg Figure 5 As shown in the figure), they may also be different, such as staggered, as long as the first clamping member 210 and the second clamping member 220 can clamp the leaflet LF together when the first clamping member 210 is closed.

[0084] In some embodiments, in combination Figure 5The valve clamping device 10 further includes a fixing seat 610 and a connecting rod 620. The distal end of the control rod 400 is fixedly connected to the fixing seat 610, one end of the connecting rod 620 is rotatably connected to the fixing seat 610, and the other end of the connecting rod 620 is rotatably connected to the middle part of the first clamping member 210.

[0085] The control rod 400 pulls the fixing seat 610 to move along the Z direction, so as to realize the rotation of the connecting rod 620 and the first clamping member 210, thereby controlling the first clamping member 210 to close or open.

[0086] It is understandable that in other embodiments, the distal end of the control rod 400 may also be directly rotatably connected to the first clamping member 210 to control the first clamping member 210 to close or open.

[0087] It should be noted that there are many structural forms in which the locking block 500 is configured to move toward the second through hole 302 when abutting against the locking base 100 .

[0088] In one possible example, combining Figure 6 and Figure 7 , one end of the lock block 500 is connected to the lock core 300, and there is a gap between the other end of the lock block 500 and the lock core 300. In this way, the other end of the lock block 500 is a free end, which can be elastically bent and deformed, and bend toward the second through hole 302 to lock the control rod 400 located in the second through hole 302. The side wall of the lock block 500 away from the second through hole 302 has a first protrusion 510. When the first protrusion 510 abuts against the lock seat 100, due to the obstruction of the lock seat 100, the first protrusion 510 drives the lock block 500 to move toward the second through hole 302 to clamp the control rod 400 located in the second through hole 302, thereby locking the control rod 400. When the first protrusion 510 is separated from the lock seat 100, without the restriction of the lock seat 100, the lock block 500 is reset to unlock the control rod 400.

[0089] Specifically, combined Figure 6 and Fig.16 The proximal end of the first protrusion 510 has a first inclined surface 511. When the lock core 300 drives the lock block 500 to move from the distal end to the proximal end, the first inclined surface 511 can guide the lock block 500 to gradually move toward the second through hole 302, thereby avoiding a sudden increase in resistance from the lock base 100 and preventing the first protrusion 510 from breaking.

[0090] Specifically, combined Figure 6 and Fig.16The distal end of the first protrusion 510 has a second inclined surface 512. When the lock core 300 drives the lock block 500 to move from the proximal end to the distal end, the first inclined surface 511 can guide the lock block 500 to gradually move toward the second through hole 302, thereby avoiding a sudden increase in resistance from the lock base 100 and preventing the first protrusion 510 from breaking.

[0091] Optionally, combined Figure 8 and Fig. 9 The lock block 500 and the lock core 300 are integrally formed. Figure 8 In the illustrated embodiment, the locking block 500 is located at the distal end of the lock core 300. It is understood that in other embodiments, the locking block 500 may also be located in the middle of the lock core 300. Since there is a gap between the remaining end of the locking block 500 and the lock core 300, it can also move toward the second through hole 302 to achieve locking of the control rod 400.

[0092] Optionally, the locking block 500 is a hard metal block. For example, the locking block 500 is a nickel-titanium alloy block, a cobalt-chromium alloy block or a stainless steel block. Among them, since nickel-titanium alloy has excellent physical and chemical properties, nickel-titanium alloy material has good elasticity, bending resistance, corrosion resistance and stability, and is non-toxic. Therefore, combined with Figure 5 The locking block 500 formed of nickel-titanium alloy material has a certain resilience, so that the locking block 500 can be reset in a natural state and can be bent and clamp the control rod 400 under the support of the lock seat 100.

[0093] Optionally, combined Figure 8 , Fig. 9 and Fig.15 The second through hole 302 is provided with a second protrusion 303 on the inner wall near the locking block 500. When the locking block 500 moves toward the inside of the second through hole 302, the second protrusion 303 abuts against the control rod 400 located in the second through hole 302, thereby increasing the clamping force of the lock core 300 clamping the control rod 400. When the locking block 500 is reset, the second protrusion 303 is reset accordingly, and no longer clamps the control rod 400, so that the control rod 400 is unlocked and can move smoothly in the second through hole 302.

[0094] Optionally, there is one locking block 500 , and one locking block 500 moves toward the inside of the second through hole 302 . The locking block 500 and the side wall of the second through hole 302 can clamp the control rod 400 to lock the control rod 400 .

[0095] Of course, see Fig. 9 The number of the locking blocks 500 may also be two (see Fig. 9 ), that is, a two-petal structure. The two locking blocks 500 are closed together to clamp the control rod 400 located in the second through hole 302, thereby locking the control rod 400. Figure 8The number of the locking blocks 500 may also be three (see Figure 8 The three locking blocks 500 are closed together to clamp the control rod 400 located in the second through hole 302, thereby locking the control rod 400. It can be understood that in other embodiments, the number of the locking blocks 500 can also be four or five.

[0096] Among them, after the number of locking blocks 500 increases, the rigidity of a single locking block 500 is smaller, and less driving force is required to complete locking or unlocking. Compared with the two-petal structure, a greater locking force can be achieved by applying the same driving force, but too many petals will also cause the strength of a single petal to become weak and easy to break. After comprehensive consideration and testing, the locking block 500 is a three-petal structure.

[0097] When the number of the locking blocks 500 is more than two, the more than two locking blocks 500 are spaced apart along the circumference of the lock core 300 .

[0098] In some embodiments, see Figure 6 and Figure 7 The inner wall of the first through hole 101 has a third inclined surface 103. The third inclined surface 103 gradually tilts outwards along the direction from the proximal end of the lock seat 100 to the distal end of the lock seat 100, and the third inclined surface 103 is used to guide the locking block 500 to gradually move toward the second through hole 302 when moving along the direction from the distal end of the lock seat 100 to the proximal end of the lock seat 100.

[0099] When the lock core 300 drives the lock block 500 to move from the distal end to the proximal end, the setting of the third inclined surface 103 causes the lock seat 100 to gradually increase the resistance of the lock block 500, guiding the lock block 500 to gradually move toward the second through hole 302, avoiding a sudden increase in resistance that may cause the lock block 500 to break.

[0100] In some embodiments, please combine Fig.10 and Fig.11 The valve clamping device 10 further includes a first elastic member 630 . The first elastic member 630 is mounted on the lock seat 100 , and is used to apply elastic force to the lock core 300 , so as to drive the lock core 300 to drive the lock block 500 to move to abut against the lock seat 100 .

[0101] When the operator pushes the lock block 500 to move away from the lock base 100, the first elastic member 630 is compressed and stores elastic potential energy. When the thrust is removed, the lock core 300 and the lock block 500 are pushed back to the lock base 100 under the resilience of the first elastic member 630, and the lock block 500 abuts against the lock base 100, and under the action of the third inclined surface 103 of the lock base 100, it quickly moves toward the inside of the second through hole 302 and clamps the control rod 400, thereby achieving rapid locking.

[0102] Specifically, the first elastic member 630 is a spring (see Fig.10 ) or shrapnel (see Fig.11 ).

[0103] Specifically, combined Fig.10 and Fig.11 The first elastic member 630 is movably connected to the lock core 300 .

[0104] Specifically, combined Fig.10 and Fig.11 The lock core 300 is provided with a push surface 304 for abutting against the first elastic member 630. The first elastic member 630 abuts against the push surface 304, thereby applying an elastic force to the lock core 300.

[0105] Optionally, the pushing surface 304 is a flange protruding from the outer periphery of the lock core 300 .

[0106] exist Fig.10 and Fig.11 In the illustrated embodiment, one end of the first elastic member 630 may be abutted, welded, or bonded to the lock base 100 , the middle portion of the first elastic member 630 movably sleeves the lock core 300 , and the other end of the first elastic member 630 abuts against the push surface 304 .

[0107] In other embodiments, please refer to Fig.12 The inner wall of the first through hole 101 has a fourth inclined surface 104. The fourth inclined surface 104 gradually tilts outwards along the direction from the distal end of the lock seat 100 to the proximal end of the lock seat 100, and the fourth inclined surface 104 is used to guide the locking block 500 to gradually move toward the second through hole 302 when moving along the direction from the proximal end of the lock seat 100 to the distal end of the lock seat 100.

[0108] exist Fig.12 In the illustrated embodiment, when the lock core 300 drives the lock block 500 to move from the proximal end to the distal end, the setting of the fourth inclined surface 104 causes the lock seat 100 to gradually increase the resistance of the lock block 500, thereby guiding the lock block 500 to gradually move toward the second through hole 302, thereby avoiding a sudden increase in resistance that would cause the lock block 500 to break.

[0109] In this way, through the structural design of the lock block 500 and the lock seat 100, the lock core 300 can be designed to move from the far end to the near end to achieve the lock block 500 locking the control rod 400, or the lock core 300 can be designed to move from the near end to the far end to achieve the lock block 500 locking the control rod 400.

[0110] like Fig.13 and Fig.14 In the illustrated embodiment, by configuring the first elastic member 630 , the locking block 500 can also be used to quickly lock the control rod 400 .

[0111] In order to enrich the structural form in which the lock block 500 is configured to move toward the second through hole 302 when abutting against the lock seat 100, in a possible example, Fig.16 The lock base 100 is not provided with the third inclined surface 103 or the fourth inclined surface 104. The proximal end of the lock block 500 is provided with a first inclined surface 511, so that when the lock core 300 moves from the distal end to the proximal end, the lock block 500 abuts against the lock base 100 and moves toward the inside of the second through hole 302 under the action of the first inclined surface 511, thereby clamping and locking the control rod 400 located in the second through hole 302.

[0112] Alternatively, a second inclined surface 512 is provided at the distal end of the locking block 500, so that when the lock core 300 moves from the proximal end to the distal end, the locking block 500 abuts against the lock seat 100 and moves toward the inside of the second through hole 302 under the action of the second inclined surface 512, thereby clamping and locking the control rod 400 located in the second through hole 302.

[0113] In order to enrich the structural form in which the lock block 500 is configured to move toward the second through hole 302 when abutting against the lock seat 100, in a possible example, Fig.17 The lock block 500 can be slidably installed on the lock core 300 along the radial direction X of the second through hole 302.

[0114] For example, Fig.17 In the illustrated embodiment, when the lock core 300 moves in the distal to proximal direction, the locking block 500 abuts against the lock seat 100 and moves toward the inside of the second through hole 302 along the radial direction X of the second through hole 302 under the obstruction of the lock seat 100, thereby clamping and locking the control rod 400 located in the second through hole 302.

[0115] At this time, the lock base 100 can be provided with a third inclined surface 103 (see Figure 6 ) or the fourth inclined surface 104 (see Fig.12 ), or none of them can be set (such as Fig.17 shown).

[0116] Optionally, a second elastic member 660 is provided between the locking block 500 and the lock core 300 , and the second elastic member 660 is used to apply an elastic force to the locking block 500 to move the locking block 500 along the radial direction X of the second through hole 302 toward the inside away from the second through hole 302 .

[0117] In order to enrich the structural form in which the lock block 500 is configured to move toward the second through hole 302 when abutting against the lock seat 100, in a possible example, Fig.18 The lock block 500 is rotatably mounted on the lock core 300 .

[0118] For example, Fig.18In the illustrated embodiment, when the lock core 300 moves in the distal to proximal direction, the lock block 500 abuts against the lock base 100 and rotates toward the inside of the second through hole 302 under the obstruction of the lock base 100, thereby clamping and locking the control rod 400 located in the second through hole 302.

[0119] At this time, the lock base 100 can be provided with a third inclined surface 103 (see Fig.18 ) or the fourth inclined surface 104 (see Fig.12 ), or neither setting is required.

[0120] Specifically, the lock block 500 is rotatably mounted on the lock core 300 via the rotating shaft 670 .

[0121] Specifically, a torsion spring is sleeved on the rotating shaft 670, and the torsion spring is used to apply an elastic force to the locking block 500, so that the locking block 500 rotates away from the inside of the second through hole 302 to release the lock of the control rod 400. In this way, in a natural state, the locking block 500 does not enter the inside of the second through hole 302.

[0122] In some embodiments, in combination Figures 19 to 21 The valve clamping device 10 further includes an unlocking rod 640 and a pull rod 650. The distal end of the unlocking rod 640 is detachably connected to the proximal end of the lock core 300, the pull rod 650 is movably arranged in the unlocking rod 640 and the lock core 300, and the distal end of the pull rod 650 is detachably connected to the proximal end of the control rod 400.

[0123] In this way, the operator manipulates the control rod 400 through the pull rod 650 to control the first clamping member 210 to close or open relative to the lock seat 100 through the pull rod 650. When the first clamping member 210 is closed and the free edge of the leaflet is clamped and fixed with the second clamping member 220, the operator manipulates the lock core 300 through the unlocking rod 640 to make the lock block 500 abut against the lock seat 100 and clamp the control rod 400 located in the second through hole 302. Then, the pull rod 650 is separated from the control rod 400, and the unlocking rod 640 is separated from the lock core 300, so that the valve clamping device 10 is implanted in the human heart and the front and rear leaflets are clamped, so that the front and rear leaflets of the mitral valve are well aligned and the regurgitation is reduced.

[0124] Specifically, the side of the distal end of the unlocking rod 640 has a first notch 641, and the proximal end of the lock core 300 has a second notch 305 facing the first notch 641. The first notch 641 is used to accommodate the proximal end of the lock core 300, and the second notch 305 is used to accommodate the distal end of the unlocking rod 640, so that the lock core 300 and the unlocking rod 640 can be detachably engaged.

[0125] Optionally, the side wall of the first notch 641 near the proximal end has a first arc surface, so that the distal end of the unlocking rod 640 can quickly enter or leave the first notch 641, thereby achieving rapid connection and separation between the unlocking rod 640 and the lock core 300.

[0126] Optionally, the side wall of the second notch 305 near the distal end has a second arc surface, so that the proximal end of the lock core 300 can quickly enter or leave the second notch 305, thereby achieving rapid connection and separation between the unlocking rod 640 and the lock core 300.

[0127] Specifically, the pull rod 650 is threadedly connected to the control rod 400, so that the two can be detachably connected. The operator can connect or separate the pull rod 650 from the control rod 400 by rotating the pull rod 650.

[0128] The proximal handle 20 of the valve clamping system 1 has a first operating member 21 and a second operating member 22 . The first operating member 21 is used to connect with the pull rod 650 to operate the pull rod 650 , and the second operating member 22 is used to connect with the unlocking rod 640 to operate the unlocking rod 640 .

[0129] The working process of the valve clamping system 1 and the valve clamping device 10 in a specific embodiment is described in detail below:

[0130] Combination Figure 5 and Fig. 22 , the valve clamping device 10 of the valve clamping system 1 enters the heart through the delivery pin tube 30, at which time, the first clamping member 210 is opened and located on the outside of the leaflet LF, and the second clamping member 220 is located on the inside of the leaflet LF. Figure 5 and Fig.23 , the control rod 400 pulls the fixing seat 610 to move toward the distal end, driving the end of the connecting rod 620 to move downward, so that the first clamping member 210 closes, and the first clamping member 210 and the second clamping member 220 clamp the fixed leaflet LF. Figure 5 and Fig.10 The operator rotates the lock core 300, and with the help of the threaded connection between the lock core 300 and the lock base 100, the lock core 300 is driven to move from the distal end to the proximal end. Under the elastic force of the first elastic member 630, the lock block 500 can quickly abut against the third inclined surface 103, and move toward the second through hole 302 under the action of the third inclined surface 103, clamping and locking the control rod 400 located in the second through hole 302. Figures 19 to 21 The operator rotates the pull rod 650 through the first operating member 21 to separate the pull rod 650 from the control rod 400 (see Fig. 20), and then the unlocking rod 640 is pulled by the second operating member 22. Since there is no radial restriction of the pull rod 650, the unlocking rod 640 and the lock cylinder 300 can be radially staggered from each other through the first notch 641 and the second notch 305 and then quickly separated (see Fig.21 Finally, the operator pulls the proximal handle 20 to remove the delivery pin tube 30 from the human body, and the valve clamping device 10 is implanted in the heart (see Fig.24 ).

[0131] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A valve clamping device, characterized in that: include: A lock seat, wherein the lock seat has a first through hole, and at least part of the inner wall of the first through hole has an internal thread; the axial direction of the lock seat refers to the direction from the distal end of the lock seat to the proximal end of the lock seat, and the circumferential direction of the lock seat refers to the direction around the axial direction of the lock seat; A first clamping member, wherein the number of the first clamping members is at least two, the at least two first clamping members are spaced apart and distributed along the circumference of the lock seat, and one end of the first clamping member is rotatably mounted on the lock seat; A second clamping member, the number of the second clamping members is at least two, the at least two second clamping members are spaced apart along the circumference of the lock seat and are located on the inner side of the first clamping member, and one end of the second clamping member is mounted on the lock seat; A lock core, wherein the lock core is inserted into the first through hole, at least a portion of the outer wall of the lock core has an outer thread matching the inner thread, and a middle portion of the lock core has a second through hole; A control rod, which is movably disposed in the second through hole, is connected to the first clamping member, and is used to drive at least two of the first clamping members to open or close relative to the lock seat; A locking block is movably mounted on the lock core, and the locking block is configured to move toward the second through hole when abutting against the lock seat to clamp the control rod located in the second through hole.

2. The valve clamping device according to claim 1, characterized in that: One end of the locking block is connected to the lock core, and a gap is formed between the other end of the locking block and the lock core. A side wall of the locking block away from the second through hole has a first protrusion, and when the first protrusion abuts against the lock seat, it drives the locking block to move toward the second through hole to clamp the control rod located in the second through hole.

3. The valve clamping device according to claim 2, characterized in that: The valve clamping device further comprises at least one of the following: The proximal end of the first protrusion has a first inclined surface; The distal end of the first protrusion has a second inclined surface; The lock block and the lock core are integrally formed; The locking block is a hard metal block; A second protrusion is provided on the inner wall of the second through hole close to the locking block.

4. The valve clamping device according to claim 1, characterized in that: The inner wall of the first through hole has a third inclined surface, and the third inclined surface gradually inclines outward along the direction from the proximal end of the lock seat to the distal end of the lock seat, and the third inclined surface is used to guide the locking block to gradually move toward the second through hole when moving along the direction from the distal end of the lock seat to the proximal end of the lock seat; Alternatively, the inner wall of the first through hole has a fourth inclined surface, which gradually inclines outward along the direction from the distal end of the lock seat to the proximal end of the lock seat, and the fourth inclined surface is used to guide the locking block to gradually move toward the second through hole when moving along the direction from the proximal end of the lock seat to the distal end of the lock seat.

5. The valve clamping device according to claim 1, characterized in that: The number of the locking blocks is one, two, three, four or five; Alternatively, the number of the locking blocks is more than two, and the more than two locking blocks are distributed at intervals along the circumference of the lock core.

6. The valve clamping device according to claim 1, characterized in that: The valve clamping device also includes a first elastic member, which is installed on the lock seat. The first elastic member is used to apply elastic force to the lock core to drive the lock core to drive the lock block to move to abut against the lock seat.

7. The valve clamping device according to claim 6, characterized in that: The valve clamping device further comprises at least one of the following: The first elastic member is a spring or a spring; The first elastic member is movably sleeved on the lock core; The lock core is provided with a pushing surface for abutting against the first elastic member.

8. The valve clamping device according to claim 1, characterized in that: The valve clamping device also includes an unlocking rod and a pull rod, the distal end of the unlocking rod is detachably connected to the proximal end of the lock core, the pull rod is movably inserted into the unlocking rod and the lock core, and the distal end of the pull rod is detachably connected to the proximal end of the control rod.

9. The valve clamping device according to claim 8, characterized in that: The side of the distal end of the unlocking rod has a first notch, and the proximal end of the lock core has a second notch facing the first notch, the first notch is used to accommodate the proximal end of the lock core, and the second notch is used to accommodate the distal end of the unlocking rod; And / or, the pull rod is threadably connected to the control rod.

10. The valve clamping device according to any one of claims 1 to 9, characterized in that: The valve clamping device also includes a fixing seat and a connecting rod, the distal end of the control rod is fixedly connected to the fixing seat, one end of the connecting rod is rotatably connected to the fixing seat, and the other end of the connecting rod is rotatably connected to the middle part of the first clamping member.

11. A valve clamping system, characterized in that: It comprises a proximal handle, a delivery pin tube and a valve clamping device as described in any one of claims 1 to 10, wherein the proximal end of the delivery pin tube is fixedly connected to the distal end of the proximal handle, the distal end of the delivery pin tube is fixedly connected to the locking seat, and the proximal handle is used to operate the valve clamping device.

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