An integrated biological sample transfer mechanism
By utilizing an integrated biosample transfer mechanism and the coordinated operation of lifting, pulling, pushing, and tube picking components, the problem of low transfer efficiency of cryopreservation racks and cryopreservation tubes in traditional biobanks has been solved, achieving efficient transfer of cryopreservation tubes and efficient operation of the biobank.
Patent Information
- Application Number
- CN202211123465.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-09-15
- Publication Date
- 2026-02-06
- Estimated Expiration
- 2042-09-15
AI Technical Summary
Traditional biobanks suffer from low efficiency in transferring cryopreservation racks and cryovials, especially in large biobanks. Cryopreservation rack transfer modules waste a lot of time transferring to distant locations, and cryovial transfer modules cannot work continuously, resulting in overall low efficiency.
An integrated biological sample transfer mechanism was designed, including a support box, lifting components, pull-pull components, lifting components, transfer components, and tube picking components. The integrated design enables efficient transfer of cryopreservation racks, cryopreservation boxes, and cryopreservation tubes. The mechanism utilizes components such as electric grippers, servo motors, and lead screws to work together to achieve rapid positioning and transfer of cryopreservation racks and cryopreservation boxes.
It improves the transfer efficiency of cryovials, reduces the transfer time of cryovial racks and boxes, enables continuous transfer of cryovials, and enhances the working efficiency of biobanks.
Smart Images

Figure CN115489913B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application belongs to the technical field of biological sample storage and access, and particularly relates to an integrated biological sample transfer mechanism. BACKGROUND
[0002] A biological sample bank, also known as a biological bank, is a storage library in which samples are classified and stored in a low-temperature storage refrigerator and can be automatically and intelligently accessed. The main automated equipment access device is a sample transfer device, which is composed of a cryopreservation rack transfer module, a cryopreservation box transfer module, and a cryopreservation tube transfer module.
[0003] Currently, the traditional sample transfer process is that the cryopreservation rack transfer module first takes out a cryopreservation rack to be taken out from a refrigerator, then moves the cryopreservation rack to a temporary storage refrigerator, then the cryopreservation box transfer module in the temporary storage refrigerator takes out the cryopreservation box to be taken out from the cryopreservation rack to be taken out, then the cryopreservation rack transfer module puts the taken-out cryopreservation rack back and takes out the next cryopreservation rack, at the same time, the cryopreservation box transfer module transfers the taken-out cryopreservation box to a tube picking platform, and finally the cryopreservation tube transfer module transfers the cryopreservation tube to be taken out in the taken-out cryopreservation box to an empty cryopreservation box.
[0004] Due to the large volume of the biological sample bank, the cryopreservation rack transfer module wastes a long time in transferring cryopreservation racks at a far position, and the cryopreservation tube transfer module cannot work continuously. After transferring the cryopreservation tubes to be taken out in a target cryopreservation box, the cryopreservation tube transfer module needs to wait for the cryopreservation box transfer module to put the taken-out cryopreservation box back and transfer a new cryopreservation box to be taken out before continuing to perform the cryopreservation tube picking work. When a large number of different cryopreservation racks or different cryopreservation boxes on the same cryopreservation rack need to be taken out, the efficiency is very low. Therefore, it is urgent to research an integrated biological sample transfer mechanism to solve the above problems. SUMMARY
[0005] The present application provides an integrated biological sample transfer mechanism, which aims to solve the technical problems proposed in the background.
[0006] To solve the above technical problems, the present application is realized by the following technical scheme:
[0007] The application discloses an integrated biological sample delivery mechanism which comprises a support box, a first electric clamp jaw, a second electric clamp jaw, a freezing rack and a first freezing box.
[0008] As a preferred technical scheme of the application, a second containing chamber corresponding to the lifting assembly is vertically arranged on one side wall of the support box; the lifting assembly comprises a support fixed to the top end of the support box; a first servo motor is vertically fixed to the support; a first pulley is fixedly arranged on the output shaft of the first servo motor; a second pulley is drivingly connected to the first pulley through a belt; the second pulley is fixedly arranged on the upper end of a vertically arranged first lead screw; the first lead screw is rotatably connected in the second containing chamber; and a first nut for mounting the first electric clamp jaw is arranged on the first lead screw.
[0009] As a preferred technical scheme of the application, the pull-push assembly comprises a pair of first guide rails fixed to the opposite side walls of the recess respectively; a push-pull frame in a U-shaped structure is horizontally arranged between the two first guide rails; clamping pieces for limiting the first freezing box are arranged on the opposite ends of the push-pull frame; a second nut is fixed to one side edge of the push-pull frame; a second lead screw is inserted through the second nut; the second lead screw is rotatably connected in the recess; one end of the second lead screw extends into the first containing chamber and is coaxially fixed to the output shaft of a second servo motor; and the second servo motor is fixed to an outer side wall of the workbench.
[0010] As a preferred technical scheme of the present application, the opposite ends of the push-pull frame are internally provided with third accommodating chambers; a first gear is rotatably arranged in the third accommodating chamber; a first rack and a second rack are engaged on the first gear; the first rack and the second rack are perpendicular to each other; the length direction of the first rack is parallel to the length direction of the side edge of the push-pull frame; the first rack is fixed in parallel on a driving rod; the driving rod is slidably inserted into the side edge of the push-pull frame, and the two ends of the driving rod can extend out of the side edge of the push-pull frame; the second rack is fixed in parallel on a limiting rod; the limiting rod is slidably inserted into a side wall of the third accommodating chamber, and one end of the limiting rod can extend to the inside of the push-pull frame.
[0011] As a preferred technical scheme of the present application, the jacking assembly comprises a mounting box fixed in the cavity; a plurality of jacking columns are vertically arranged and slidably inserted into the top wall of the mounting box; an iron sheet is horizontally fixed at the lower end of the jacking column; a first electromagnet is arranged below the iron sheet; the first electromagnet is fixed on the bottom wall of the mounting box; a second electromagnet is arranged above the iron sheet; the second electromagnet is fixed on the top wall of the mounting box.
[0012] As a preferred technical scheme of the present application, the transfer assembly comprises a pair of second guide rails which are respectively horizontally fixed at the opposite edges of the upper end of the cavity; the second guide rails are vertically arranged with the first guide rails; a third screw rod is rotatably connected in parallel on the second guide rail; one end of the third screw rod is coaxially fixed on a third servo motor; the third servo motor is fixed on one end of the second guide rail; a plurality of third nuts are sleeved side by side on the third screw rod; a second cryopreservation box is horizontally fixed on the third nut; the second cryopreservation box is slidably connected between the two second guide rails.
[0013] As a preferred technical scheme of the present application, the bearing assembly comprises a third guide rail which is fixed in parallel on one side surface of the second guide rail; a fourth screw rod is rotatably connected in parallel on the third guide rail; one end of the fourth screw rod is coaxially fixed on the output shaft of a fourth servo motor; the fourth servo motor is fixed on one end of the third guide rail; a fourth nut is sleeved on the fourth screw rod; a third cryopreservation box is horizontally fixed on the fourth nut; the third cryopreservation box is slidably connected on the third guide rail.
[0014] As a preferred technical scheme of the present application, the first freezing box, the second freezing box and the third freezing box are identical in structure; the first freezing box comprises a horizontally arranged bottom plate; the four edges of the bottom plate are integrally formed with limiting protrusions; a plurality of through holes are uniformly arranged on the upper surface of the bottom plate; a box body is fixed to the upper surface of the bottom plate; a plurality of storage holes corresponding to the through holes are vertically arranged on the box body; a positioning plate is horizontally fixed above the box body; a plurality of positioning holes corresponding to the storage holes are uniformly arranged on the upper surface of the positioning plate; the positioning plate is made of elastic material; and the diameter of the positioning hole is smaller than that of the storage hole.
[0015] As a preferred technical scheme of the present application, the tube picking assembly comprises a fourth guide rail vertically fixed at one end to one side wall of the support box; the fourth guide rail is vertically arranged with the third guide rail; a third rack is fixed in parallel on the fourth guide rail; a sliding frame is slidably connected to the fourth guide rail; a fifth servo motor is vertically fixed to the upper edge of the sliding frame; a second gear meshing with the third rack is fixed to the output shaft of the fifth servo motor; an electric push rod is vertically fixed to the lower edge of the sliding frame; and the output shaft of the electric push rod is connected with the second electric clamping jaw.
[0016] The present application has the following advantages:
[0017] Based on the integrated structure design, the first electric clamping jaw is first moved to the lower end of the support box by the lifting assembly, and the freezing rack carrying the first freezing box (the freezing tube is carried on the first freezing box) is clamped by the first electric clamping jaw, then the freezing rack is moved into the support box by the lifting assembly by driving the first electric clamping jaw to move upward, and the first freezing box on the freezing rack is correspondingly positioned with the transfer window, then the first freezing box on the freezing rack is pushed into the recessed cavity through the transfer window and the through hole by the pulling and pushing assembly, and the first freezing box is arranged directly above the jacking assembly, then the freezing tube in the first freezing box above is pushed onto the transfer assembly by the jacking assembly, and then the freezing tube on the transfer assembly is transferred to the bearing assembly by the tube picking assembly, so that the transfer of the freezing tube is realized, and the transfer efficiency of the freezing tube is effectively improved compared with the prior art, and the present application has high market application value.
[0018] Of course, any product implementing the present application does not necessarily need to achieve all the advantages described above. BRIEF DESCRIPTION OF DRAWINGS
[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed for the description of the embodiments will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.
[0020] Figure 1 A structural schematic view of a one-piece biological sample delivery mechanism of the present application.
[0021] Figure 2 A structural schematic view of the connection between the support box, the lifting assembly and the workbench of the present application.
[0022] Figure 3 A structural schematic view of the support box of the present application.
[0023] Figure 4 A structural schematic view of the cryogenic storage rack of the present application.
[0024] Figure 5 A structural schematic view of the first cryogenic storage box of the present application.
[0025] Figure 6 A structural schematic view of the lifting assembly of the present application.
[0026] Figure 7 A structural schematic view of the connection between the workbench, the pull-push assembly and the jacking assembly of the present application.
[0027] Figure 8 A structural schematic view of the connection between the workbench and the jacking assembly of the present application.
[0028] Figure 9 A structural schematic view of Figure 8 A structural front view of
[0029] Figure 10 A structural schematic view of the pull-push assembly of the present application.
[0030] Figure 11 A structural schematic view of the detent of the present application.
[0031] Figure 12 A structural schematic view of the installation of the transfer assembly and the bearing assembly on the workbench of the present application.
[0032] Figure 13 A structural schematic view of the connection between the transfer assembly and the bearing assembly of the present application.
[0033] Figure 14 A structural schematic view of the tube picking assembly of the present application.
[0034] Figure 15 A structural schematic view of the connection between the third rack and the second gear of the present application.
[0035] In the drawings, the components represented by each reference numeral are listed as follows:
[0036] 1-support box, 2-first electric clamping jaw, 3-second electric clamping jaw, 4-freezing rack, 5-first freezing box, 6-lifting assembly, 7-workbench, 8-pull-push assembly, 9-jacking assembly, 10-transferring assembly, 11-bearing assembly, 12-pipe-picking assembly, 101-passing window, 102-second containing cavity, 103-convex cavity, 501-bottom plate, 502-box body, 503-positioning plate, 601-stand, 602-first servo motor, 603-first pulley, 604-second pulley, 605-first screw rod, 606-first nut, 701-concave cavity, 702-through hole, 703-first containing cavity, 801-first guide rail, 802-pull-pull frame, 8021-third containing cavity, 803-second screw rod, 804-second servo motor, 805-first gear, 806-first rack, 807-second rack, 808-driving rod, 809-limiting rod, 901-mounting box, 902-jacking column, 903-first electromagnet, 904-second electromagnet, 1001-second guide rail, 1002-third screw rod, 1003-third servo motor, 1004-second freezing box, 1101-third guide rail, 1102-fourth screw rod, 1103-fourth servo motor, 1104-third freezing box, 1201-fourth guide rail, 1202-third rack, 1203-sliding frame, 1204-fifth servo motor, 1205-second gear, 1206-electric push rod, 5011-limiting convex, 5012-through hole, 5021-storing hole, 5031-positioning hole. DETAILED DESCRIPTION
[0037] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all the other embodiments obtained by a person of ordinary skill in the art without creative work are within the protection scope of the present application. Embodiment one
[0039] Please refer to Figures 1-2 , Figure 4 , Figures 7-8 and Figure 12As shown, the present application is a kind of integrated biological sample delivery mechanism, including support box 1, the first electric clamping jaw 2 of conventional in the art, the second electric clamping jaw 3 of conventional in the art, the conventional cryopreservation rack 4 of the art and the conventional first cryopreservation box 5 of the art;The lower part of support box 1 is open structure;Support box 1 is equipped with lifting assembly 6;Lifting assembly 6 is equipped with second electric clamping jaw 3;Second electric clamping jaw 3 is used to clamp cryopreservation rack 4;Cryopreservation rack 4 can be loaded with multiple first cryopreservation boxes 5 distributed above and below side by side;The side wall of support box 1 is provided with delivery window 101;The side wall of support box 1 is horizontally fixed with workbench 7 corresponding to delivery window 101;The upper surface of workbench 7 is provided with recess 701;The opposite sides of recess 701 are respectively provided with through hole 702 and first containing chamber 703;Through hole 702 is communicated with delivery window 101;First containing chamber 703 is equipped with pull-push assembly 8 for pushing first cryopreservation box 5 on cryopreservation rack 4 in support box 1 through delivery window 101 and through hole 702 into recess 701;Recess 701 is equipped with jacking assembly 9 for ejecting cryopreservation tube on first cryopreservation box 5 in recess 701 out of recess 701;Jacking assembly 9 is equipped with transfer assembly 10 for carrying ejected cryopreservation tube above;Transfer assembly 10 is equipped with carrying assembly 11 away from support box 1;Carrying assembly 11 is equipped with tube picking assembly 12 for transferring cryopreservation tube on transfer assembly 10 to carrying assembly 11 above.In use, first electric clamping jaw 2 is moved to the lower end of support box 1 by lifting assembly 6, and cryopreservation rack 4 loaded with first cryopreservation box 5 (cryopreservation tube is loaded on first cryopreservation box 5) is clamped by first electric clamping jaw 2, then cryopreservation rack 4 is moved into support box 1 by lifting assembly 6 by driving first electric clamping jaw 2 to move upward, and the first cryopreservation box 5 to be delivered on cryopreservation rack 4 corresponds to the position of delivery window 101, then first cryopreservation box 5 on cryopreservation rack 4 is pushed into recess 701 through delivery window 101 and through hole 702 by pull-push assembly 8, and first cryopreservation box 5 is arranged directly above jacking assembly 9, then the cryopreservation tube in first cryopreservation box 5 above is pushed onto transfer assembly 10 by jacking assembly 9, then the cryopreservation tube on transfer assembly 10 is transferred to carrying assembly 11 by tube picking assembly 12, so as to realize the transfer of cryopreservation tube, which effectively improves the transfer efficiency of cryopreservation tube compared with the prior art. Specific embodiment two:
[0041] On the basis of specific embodiment one, such as Figures 2-3 And Figure 6As shown, one side wall of the support box 1 is vertically provided with a second accommodating chamber 102 corresponding to the lifting assembly 6; the lifting assembly 6 comprises a support 601 fixed to the top end of the support box 1; the support 601 is in a "j" type structure; a first servo motor 602 is vertically fixed on the support 601; a first pulley 603 is fixed on the output shaft of the first servo motor 602; a second pulley 604 is connected to the first pulley 603 through a belt transmission; the second pulley 604 is fixed on the upper end of a vertically arranged first lead screw 605; the first lead screw 605 is rotationally connected in the second accommodating chamber 102; a first nut 606 for mounting the first electric clamping jaw 2 is sleeved on the first lead screw 605; the first electric clamping jaw 2 is mounted on one surface of the first nut 606; the first electric clamping jaw 2 is slidingly connected to the inner side wall of the support box 1. In use, the first servo motor 602 drives the first lead screw 605 to rotate through the first pulley 603 and the second pulley 604, which drives the first nut 606 to drive the first electric clamping jaw 2 to move up and down in the support box 1, thereby achieving the lifting of the cryopreservation rack 4. Specific embodiment three:
[0043] On the basis of the specific embodiment one, as Figures 7-8 and Figures 10-11As shown, the side wall of the support box 1 away from the workbench 7 has a convex cavity 103 corresponding to the pull-push assembly 8; the pull-push assembly 8 comprises a pair of first guide rails 801 fixed to the opposite side walls of the concave cavity 701 respectively; a u-shaped push-pull frame 802 is horizontally arranged between the two first guide rails 801; the opposite ends of the push-pull frame 802 are both provided with a clamping part for limiting the first cryopreservation box 5; one side edge of the push-pull frame 802 is fixed with a second nut; a second lead screw 803 is inserted through the second nut; the second lead screw 803 is rotationally connected in the concave cavity 701; one end of the second lead screw 803 extends into the first containing chamber 703 and is coaxially fixed on the output shaft of a second servo motor 804; the second servo motor 804 is fixed on an outer side wall of the workbench 7; the opposite ends of the push-pull frame 802 are both provided with a third containing chamber 8021; a first gear 805 is rotationally arranged in the third containing chamber 8021; a first rack 806 and a second rack 807 are engaged on the first gear 805; the first rack 806 and the second rack 807 are perpendicular to each other; the length direction of the first rack 806 is parallel to the length direction of the side edge of the push-pull frame 802; the first rack 806 is arranged on the side of the first gear 805 away from the jacking assembly 9; the first rack 806 is fixed in parallel on a driving rod 808; the driving rod 808 is slidingly inserted through the side edge of the push-pull frame 802, and the two ends of the driving rod 808 can extend out of the side edge of the push-pull frame 802; one end of the driving rod 808 can abut against one surface of the convex cavity 103, and the other end of the driving rod 808 can abut against one side wall of the first containing chamber 703; the second rack 807 is fixed in parallel on a limiting rod 809; the limiting rod 809 is slidingly inserted through one side wall of the third containing chamber 8021, and one end of the limiting rod 809 can extend to the inner side of the push-pull frame 802.When the first cryogenic box 5 on the cryogenic shelf 4 needs to be transferred to the jacking assembly 9, the second servo motor 804 is driven to rotate the second screw 803 in the positive direction, so as to drive the second nut to move the push-pull frame 802 through the through hole 702 and the transfer window 101 into the support box 1 (in this process, the limiting rod 809 is in the third accommodating chamber 8021, one end of the limiting rod 809 extends out of the side edge of the push-pull frame 802, and the opposite two side edges of the push-pull frame 802 are located on the inner side of the cryogenic shelf 4 and on the opposite sides of the first cryogenic box 5). When one end of the limiting rod 809 abuts against a surface of the convex cavity 103, since the push-pull frame 802 is still moving into the support box 1, the first rack 806 drives the first gear 805 to rotate, and the second rack 807 is driven by the first gear 805 to move, so that one end of the limiting rod 809 extends to the inner side of the push-pull frame 802, thereby establishing a limiting structure for the first cryogenic box 5. Then, the second servo motor 804 is driven to rotate the second screw 803 in the reverse direction, so that the limiting rod 809 pushes the first cryogenic box 5 on the cryogenic shelf 4 out, and the first cryogenic box 5 moves into the concave cavity 701 through the transfer window 101 and the through hole 702 in sequence, and the first cryogenic box 5 corresponds to the position of the jacking assembly 9, thereby realizing the transfer of the first cryogenic box 5. Specific embodiment four:
[0045] On the basis of the specific embodiment three, as shown in Figures 7-9 , the jacking assembly 9 includes a mounting box 901 fixed in the concave cavity 701; a plurality of vertical jacking columns 902 are slidingly inserted into the top wall of the mounting box 901; an iron sheet is horizontally fixed at the lower end of the jacking column 902; a first electromagnet 903 is arranged below the iron sheet; the first electromagnet 903 is fixed to the bottom wall of the mounting box 901; a second electromagnet 904 is arranged above the iron sheet; the second electromagnet 904 is fixed to the top wall of the mounting box 901; the first cryogenic box 5 and the second electromagnet 904 both have an annular structure; the second electromagnet 904 is gap-fitted on the outer periphery of the jacking column 902. When the first cryogenic box 5 corresponds to the position of the jacking assembly 9, the first electromagnet 903 is de-energized and the second electromagnet 904 is energized, so that the iron sheet drives the jacking column 902 to move upward under the magnetic attraction, thereby realizing the transfer of the cryogenic tube on the first cryogenic box 5 to the transfer assembly 10. Specific embodiment five:
[0047] On the basis of the specific embodiment four, as shown in Figure 2 , Figures 8-9 and Figures 12-13As shown, the transfer assembly 10 comprises a pair of second guide rails 1001 horizontally fixed at opposite edges of the upper port of the cavity 701 respectively; the second guide rails 1001 are vertically arranged with the first guide rails 801; a third screw rod 1002 parallel to the second guide rails 1001 is rotatably connected to one of the second guide rails 1001; one end of the third screw rod 1002 is coaxially fixed to a third servo motor 1003; the third servo motor 1003 is fixed to one end of the second guide rail 1001; a plurality of third nuts are sleeved on the third screw rod 1002 side by side; a second cryopreservation box 1004 is horizontally fixed on the third nut; the second cryopreservation box 1004 is slidingly connected between the two second guide rails 1001. When it is needed to transfer the cryopreservation tubes on the first cryopreservation box 5 to the transfer assembly 10, the third servo motor 1003 is first driven to rotate the third screw rod 1002, so as to make any second cryopreservation box 1004 be above the first cryopreservation box 5, thereby ensuring the transfer effect of the cryopreservation tubes; by arranging a plurality of second cryopreservation boxes 1004 between the two second guide rails 1001, when the picking assembly 12 transfers the cryopreservation tubes on one second cryopreservation box 1004, the cryopreservation tubes on another second cryopreservation box 1004 can also be transferred, thereby ensuring the continuous transfer of the cryopreservation tubes, and further ensuring the transfer efficiency of the cryopreservation tubes. Specific embodiment six:
[0049] Based on the specific embodiment five, as shown in Figure 9 and Figures 12-13 The carrying assembly 11 comprises a third guide rail 1101 fixed parallel to one side surface of the second guide rail 1001; a fourth screw rod 1102 parallel to the third guide rail 1101 is rotatably connected to the third guide rail 1101; one end of the fourth screw rod 1102 is coaxially fixed to the output shaft of a fourth servo motor 1103; the fourth servo motor 1103 is fixed to one end of the third guide rail 1101; a fourth nut is sleeved on the fourth screw rod 1102; a third cryopreservation box 1104 is horizontally fixed on the fourth nut; the third cryopreservation box 1104 is slidingly connected to the third guide rail 1101. In use, the fourth servo motor 1103 is driven to rotate the fourth screw rod 1102, so as to drive the third cryopreservation box 1104 to slide on the third guide rail 1101, thereby realizing the position adjustment of the third cryopreservation box 1104, and further meeting the use requirements of the picking assembly 12.
[0050] Among them, as shown in Figure 5 and Figures 12-13As shown, the structures of the first cryobox 5, the second cryobox 1004 and the third cryobox 1104 are the same; the first cryobox 5 comprises a horizontal bottom plate 501; the four edges of the bottom plate 501 are integrally formed with limiting protrusions 5011; a plurality of through holes 5012 are uniformly arranged on the upper surface of the bottom plate 501; a box body 502 is fixed on the upper surface of the bottom plate 501; a plurality of storage holes 5021 are vertically arranged on the box body 502 and correspond to the through holes 5012; a positioning plate 503 is horizontally fixed above the box body 502; a plurality of positioning holes 5031 are uniformly arranged on the upper surface of the positioning plate 503 and correspond to the storage holes 5021; the positioning plate 503 is made of elastic material; the diameter of the positioning hole 5031 is slightly smaller than that of the storage hole 5021; the edge of the positioning hole 5031 has a notch structure; the cryotubes are in clearance fit with the through holes 5012 and the storage holes 5021, and the cryotubes are in interference fit with the positioning holes 5031, but the cryotubes can slide relative to the positioning holes 5031 under the pushing or clamping of external force. When the first cryobox 5 and the second cryobox 1004 are in position correspondence, the cryotubes in the storage holes 5021 are moved upward by the jacking column 902 passing through the through holes 5012, so as to move the cryotubes in the first cryobox 5 into the second cryobox 1004; when the second cryobox 1004 and the third cryobox 1104 are in position correspondence, the second electric clamping jaw 3 can clamp the cryotubes on the second cryobox 1004 on the third cryobox 1104, so as to realize the transfer of the cryotubes. Specific embodiment seven:
[0052] On the basis of specific embodiment six, as shown in Figure 1 and Figures 14-15 As shown, the tube picking assembly 12 comprises a fourth guide rail 1201 vertically fixed on one side wall of the support box 1; the fourth guide rail 1201 is vertically arranged with the third guide rail 1101; a third rack 1202 is fixed in parallel on the fourth guide rail 1201; a sliding frame 1203 is slidably connected to the fourth guide rail 1201; a fifth servo motor 1204 is vertically fixed on the upper edge of the sliding frame 1203; a second gear 1205 is fixedly connected to the output shaft of the fifth servo motor 1204 and meshes with the third rack 1202; an electric push rod 1206 is vertically fixed on the lower edge of the sliding frame 1203; the output shaft of the electric push rod 1206 is connected with the second electric clamping jaw 3. In use, the fifth servo motor 1204 drives the second gear 1205 to rotate, so as to make the second gear 1205 roll on the third rack 1202, thereby realizing the sliding of the sliding frame 1203 on the fourth guide rail 1201, and further realizing the horizontal position adjustment of the second electric clamping jaw 3; then the electric push rod 1206 drives the second electric clamping jaw 3 to move up and down, thereby realizing the vertical position adjustment of the second electric clamping jaw 3, and ensuring the tube picking efficiency of the tube picking assembly 12.
[0053] The preferred embodiments of the application disclosed above are only to facilitate the elucidation of the application. The preferred embodiments do not describe all the details of the application and limit the application to the specific embodiments described. Obviously, many modifications and variations can be made in light of the teachings above. The description is chosen and described in order to best explain the principles of the application and its practical application to thereby enable others skilled in the art to best utilize the application and get the best results from the application. The application is only limited by the claims and their full scope and equivalents.
Claims
1. An integrated biological sample delivery mechanism, comprising a support box (1), a first electrically operated gripper (2), a second electrically operated gripper (3), a freezing rack (4) and a first freezing box (5), characterized in that: the lower part of the support box (1) is of an open structure; the support box (1) is internally provided with a lifting assembly (6); the lifting assembly (6) is provided with the first electrically operated gripper (2); the first electrically operated gripper (2) is used for clamping the freezing rack (4); the freezing rack (4) can carry multiple first freezing boxes (5) side by side; a delivery window (101) is formed in one side wall of the support box (1); a workbench (7) corresponding to the delivery window (101) is horizontally fixed to one side wall of the support box (1); a recess (701) is formed in the upper surface of the workbench (7); through holes (702) and a first accommodating chamber (703) are respectively formed in the opposite sides of the recess (701); the through holes (702) are in communication with the delivery window (101); the first accommodating chamber (703) is internally provided with a pulling assembly (8) for pushing the first freezing boxes (5) on the freezing rack (4) in the support box (1) through the delivery window (101) and the through holes (702) into the recess (701); the recess (701) is internally provided with a jacking assembly (9) for jacking the freezing tubes on the first freezing boxes (5) in the recess (701) out of the recess (701); the jacking assembly (9) is provided with a transfer assembly (10) above for carrying the jacked freezing tubes; a bearing assembly (11) is provided on the side of the transfer assembly (10) away from the support box (1); a tube picking assembly (12) is provided above the bearing assembly (11) for transferring the freezing tubes on the transfer assembly (10) to the bearing assembly (11); the pulling assembly (8) comprises a pair of first guide rails (801) respectively fixed to the opposite side walls of the recess (701); a push-pull frame (802) in a u-shaped structure is horizontally arranged between the first guide rails (801); the opposite ends of the push-pull frame (802) are each internally provided with a third accommodating chamber (8021); a first gear (805) is rotatably arranged in the third accommodating chamber (8021); a first rack (806) and a second rack (807) are engaged on the first gear (805); the first rack (806) and the second rack (807) are perpendicular to each other; the length direction of the first rack (806) is parallel to the length direction of the side edge of the push-pull frame (802); the first rack (806) is fixed in parallel to a driving rod (808); the driving rod (808) is slidingly inserted into the side edge of the push-pull frame (802), and the two ends of the driving rod (808) can pass through the side edge of the push-pull frame (802); the second rack (807) is fixed in parallel to a limiting rod (809); the limiting rod (809) is slidingly inserted into one side wall of the third accommodating chamber (8021), and one end of the limiting rod (809) can extend to the inside of the push-pull frame (802).
2. An integrated biological sample transfer mechanism according to claim 1, wherein, The side wall of the support box (1) is vertically provided with a second containing chamber (102) corresponding to the lifting assembly (6); the lifting assembly (6) comprises a support (601) fixed to the top end of the support box (1); the support (601) is vertically fixed with a first servo motor (602); the output shaft of the first servo motor (602) is fixedly sleeved with a first pulley (603); the first pulley (603) is connected with a second pulley (604) through a belt drive; the second pulley (604) is fixedly sleeved on the upper end of a vertically arranged first lead screw (605); the first lead screw (605) is rotatably connected in the second containing chamber (102); the first lead screw (605) is sleeved with a first nut (606) for mounting the first electric clamping jaw (2).
3. An integrated biological sample transfer mechanism according to claim 1 or 2, wherein, The side edge of the push-pull frame (802) is fixed with a second nut; the second nut is inserted with a second lead screw (803); the second lead screw (803) is rotatably connected in the cavity (701); one end of the second lead screw (803) extends into the first containing chamber (703) and is coaxially fixed on the output shaft of a second servo motor (804); the second servo motor (804) is fixed on an outer side wall of the workbench (7).
4. An integrated biological sample delivery mechanism as defined in claim 3, wherein, The jacking assembly (9) comprises a mounting box (901) fixed in the cavity (701); the top wall of the mounting box (901) is slidably inserted with a plurality of vertically arranged jacking columns (902); the lower end of the jacking column (902) is fixed with an iron sheet; the lower side of the iron sheet is provided with a first electromagnet (903); the first electromagnet (903) is fixed on the bottom wall of the mounting box (901); the upper side of the iron sheet is provided with a second electromagnet (904); the second electromagnet (904) is fixed on the top wall of the mounting box (901).
5. An integrated biological sample delivery mechanism as in claim 4, wherein, The transfer assembly (10) comprises a pair of second guide rails (1001) respectively fixed horizontally on the opposite edges of the upper end of the cavity (701); the second guide rails (1001) are vertically arranged with the first guide rails (801); the second guide rail (1001) is rotatably connected with a third lead screw (1002) parallel to each other; one end of the third lead screw (1002) is coaxially fixed on a third servo motor (1003); the third servo motor (1003) is fixed on one end of a second guide rail (1001); a plurality of third nuts are sleeved on the third lead screw (1002); the second freezing box (1004) is fixed horizontally on the third nut; the second freezing box (1004) is slidably connected between the two second guide rails (1001).
6. An integrated biological sample transfer mechanism according to claim 5, wherein, The bearing assembly (11) comprises a third guide rail (1101) fixed in parallel to one side of a second guide rail (1001); the third guide rail (1101) is rotationally connected with a fourth screw rod (1102) in parallel; one end of the fourth screw rod (1102) is coaxially fixed on an output shaft of a fourth servo motor (1103); the fourth servo motor (1103) is fixed on one end of the third guide rail (1101); a fourth nut is sleeved on the fourth screw rod (1102); a third cryopreservation box (1104) is fixed horizontally on the fourth nut; and the third cryopreservation box (1104) is slidingly connected to the third guide rail (1101).
7. An integrated biological sample transfer mechanism according to claim 6, wherein, The first cryopreservation box (5), the second cryopreservation box (1004) and the third cryopreservation box (1104) are the same in structure; the first cryopreservation box (5) comprises a bottom plate (501) arranged horizontally; limit protrusions (5011) are integrally formed at four edges of the bottom plate (501); a plurality of through holes (5012) are uniformly arranged on the upper surface of the bottom plate (501); a box body (502) is fixed on the upper surface of the bottom plate (501); a plurality of storage holes (5021) corresponding to the through holes (5012) are vertically arranged on the box body (502); and a positioning plate (503) is fixed horizontally above the box body (502).
8. An integrated biological sample delivery mechanism as in claim 7, wherein, The positioning plate (503) is made of elastic material; and the diameter of the positioning hole (5031) is smaller than that of the storage hole (5021).
9. An integrated biological sample transfer mechanism according to claim 7 or 8, wherein, The pipe picking assembly (12) comprises a fourth guide rail (1201) vertically fixed at one end on one side wall of the support box (1); the fourth guide rail (1201) is vertically arranged with the third guide rail (1101); a third rack (1202) is fixed in parallel on the fourth guide rail (1201); a sliding frame (1203) is slidingly connected to the fourth guide rail (1201); a fifth servo motor (1204) is vertically fixed on the upper edge of the sliding frame (1203); a second gear (1205) engaged with the third rack (1202) is fixedly sleeved on the output shaft of the fifth servo motor (1204); an electric push rod (1206) is vertically fixed on the lower edge of the sliding frame (1203); and the output shaft of the electric push rod (1206) is connected with the second electric clamping jaw (3).
Citation Information
Patent Citations
Tube picking device
CN110615275A
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