Stent and thrombectomy system

Abstract

The present application relates to a stent and a thrombectomy system comprising the stent, wherein the stent comprises a stent body and a visualization structure, the stent body is formed by at least one closed loop net unit coupled with each other, the closed loop net unit is formed by a wave pole, the visualization structure comprises a main body visualization, the main body visualization has at least one main body visualization wire, and the main body visualization wire is wound along the wave pole and at least part of the stent body. The thrombectomy system comprises the stent and a push rod arranged at the proximal end of the stent. Through the above arrangement, the positions of the first closed loop net unit and the second closed loop net unit on the stent body can be clearly determined, the position of the stent body is convenient for the operator to determine, more information is provided for the operator to determine the position of the stent, and the visibility of the stent body is further improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a stent and a thrombus removal system comprising the stent. Background Art

[0002] Stroke, also known as cerebral infarction, is an acute cerebrovascular disease characterized by symptoms of ischemic and hemorrhagic damage to brain tissue. The 2018 "China Stroke Prevention and Treatment Report" noted that stroke in my country exhibits five major characteristics: high morbidity, high disability, high mortality, high recurrence rate, and a high economic burden. Stroke has become the leading cause of death in my country, with one person suffering a stroke every 12 seconds and one dying from it every 21 seconds. According to the 2016 standardized prevalence rate, 1.96 million people die from stroke nationwide each year, and 70% of survivors suffer varying degrees of permanent disability. Acute ischemic stroke accounts for approximately 70% to 80% of all stroke cases. The key to treatment is to restore cerebral blood flow and minimize secondary brain damage as soon as possible before permanent damage occurs due to ischemia. Currently, there are two main treatment methods for acute ischemic stroke: drug thrombolysis and mechanical thrombectomy.

[0003] Arterial and intravenous thrombolysis is a conventional treatment for acute ischemic stroke. Although it has been shown to significantly improve neurological outcomes, it still faces several challenges. First, the time window for thrombolysis is short: intravenous thrombolysis should be performed within 3 hours of onset, while the time window for arterial thrombolysis is only 6 hours. This extremely short window results in only a small number of patients being eligible for thrombolytic therapy. Second, vascular recanalization after thrombolysis is prolonged, which may be a significant factor affecting clinical prognosis. Arterial and venous thrombolysis requires at least 1–2 hours to achieve recanalization. Third, thrombolytic therapy is only suitable for smaller clots; the recanalization rate is low for acute ischemic stroke caused by severe large vessel occlusion. Finally, some patients are not suitable for thrombolytic therapy.

[0004] To address the aforementioned issues with drug thrombolysis, mechanical thrombus removal has become a research hotspot in recent years. Arterial mechanical thrombectomy devices have garnered widespread attention due to their numerous advantages: rapid recanalization, a longer time window for stroke intervention, and lower bleeding rates. They have demonstrated particularly promising clinical results in recanalizing acute ischemic stroke caused by large vessel occlusion.

[0005] At present, existing mechanical thrombectomy usually uses intracranial thrombectomy devices, which are usually metal stents made using laser cutting processing technology. However, these metal stents still have many problems to be solved. One of the main problems is that the metal stents are provided with groups of developing points or developing wires. Under X-rays, they can only show the positioning or outline of the metal stent during surgery, and cannot fully display all the metal rods of the laser-cut metal stent. Doctors cannot judge the release and local expansion of the main body of the thrombectomy device under X-rays. Only after the thrombectomy device is removed from the human body can it be observed whether a thrombus is pulled out, which is not conducive to the doctor's judgment during the operation and wastes precious treatment time.

[0006] To improve visualization, new thrombectomy devices for blood vessels have emerged on the market. These devices, in addition to multiple visualization points on the distal end of the stent, also feature multiple sets of marking points on the stent body. These markings help the operating physician determine the position and orientation of the device within the vessel. However, the visualization performance of these devices is far from optimal. Summary of the Invention

[0007] In view of the above-mentioned shortcomings of the prior art, an object of the present invention is to provide a stent and a thrombectomy system including the stent to solve one or more problems in the prior art.

[0008] To achieve the above object, the technical solution of the present invention is as follows:

[0009] A bracket, comprising a bracket body and a development structure, wherein the bracket body is formed by mutually coupling at least one closed-loop network unit, wherein the closed-loop network unit is formed by enclosing a wave rod, and the development structure comprises a main body development, wherein the main body development has at least one main body development wire, and the main body development wire is wound around at least a portion of the bracket body along the wave rod.

[0010] Furthermore, the main developing wire is spirally wound around the wave rod.

[0011] Furthermore, the main developing wire is arranged along the proximal end to the distal end of the stent body or along the distal end to the proximal end of the stent body.

[0012] Furthermore, the main developing wire forms a developing net unit along the path of the wave rod winding around the stent body, and the developing net unit marks the structure and / or position of the stent.

[0013] Furthermore, the developing screen unit is a closed geometric shape;

[0014] or,

[0015] The developing web unit has a semi-open geometric shape.

[0016] Furthermore, the area of ​​the developing mesh unit is the same as the area of ​​the closed loop mesh unit of the support body at this position;

[0017] or,

[0018] The area of ​​the developing mesh unit is smaller than the area of ​​the closed loop mesh unit of the support body at this position;

[0019] Or,

[0020] The area of ​​the developing web unit is the sum of the areas of a plurality of the closed-loop web units at the position of the support body.

[0021] Furthermore, the closed-loop network unit includes at least one first closed-loop network unit and at least one second closed-loop network unit, and the area enclosed by the first closed-loop network unit is larger than the area enclosed by the second closed-loop network unit.

[0022] Furthermore, the area enclosed by the first closed-loop network unit is 2 to 5 times the area enclosed by the second closed-loop network unit.

[0023] Furthermore, the number of the first closed-loop network units is 1 / 20 to 1 / 3 of the number of the second closed-loop network units.

[0024] Furthermore, the main developing wire is attached to at least one of the first closed-loop net units in a winding manner, so that at least one of the first closed-loop net units can be developed on the bracket body.

[0025] The main developing wire is wound around all the corrugated rods of at least one first closed-loop network unit and is wound around part of the corrugated rods of at least one second closed-loop network unit.

[0026] Furthermore, at least one of the first closed-loop network units has a portion of wave rods wound by the main developing wire at least twice.

[0027] Furthermore, the main developing wire is wound around a portion of the corrugated rods of at least one of the first closed-loop network units and is wound around a portion of the corrugated rods of at least one of the second closed-loop network units.

[0028] Furthermore, the number of the main developing wires is at least two, one of which is wound around part of the wave rods of at least one first closed-loop network unit and part of the wave rods of at least one second closed-loop network unit, and the other is wound around the remaining wave rods of at least one first closed-loop network unit and part of the wave rods of at least one second closed-loop network unit.

[0029] Furthermore, the number of the main developing filaments is 1 to 8.

[0030] Furthermore, the development structure also includes a distal development, and the distal development is connected to the distal end of the stent body.

[0031] Furthermore, the proximal end of the distal end display is integrally connected to the distal end of the main body display or is detachably connected thereto.

[0032] Furthermore, the distal end development is that the first distal end development wire is wound around the distal end wave rod of the stent body to form at least one layer of wrapping structure.

[0033] Furthermore, the distal development is a second distal development wire, which is wound around the distal wave rod of the stent body to form an axial ring and wound around the outer side of the axial ring to form a circumferential ring.

[0034] Furthermore, the distal end development is coaxial or non-coaxial with the proximal end of the stent body.

[0035] Furthermore, the development structure further includes a proximal development, and the proximal development is connected to the proximal end of the stent body.

[0036] Furthermore, the distal end of the proximal end display is integrally connected to the proximal end of the main body display or is detachably connected thereto.

[0037] Furthermore, the proximal end development is coaxial or non-coaxial with the distal end of the stent body.

[0038] In addition, the present invention further provides a thrombus removal system, which includes the above-mentioned stent and a pushing rod arranged at the proximal end of the stent, and the pushing rod is arranged coaxially or non-coaxially with the stent.

[0039] Compared with the prior art, the beneficial technical effects of the present invention are as follows:

[0040] (1) The stent of the present invention includes a stent body and a developing structure. The stent body is formed by coupling at least one closed-loop mesh unit. The developing structure includes at least one main developing wire. The main developing wire is wound around at least a portion of the stent body along a wave rod. The main developing wire forms a developing mesh unit along the path of the wave rod. This arrangement allows the developing mesh unit to mark the structure and / or position of the stent, facilitating the operator's determination of the stent body's position, providing the operator with more information for determining the stent's position, and further improving the visibility of the stent body.

[0041] (2) Furthermore, the first closed-loop network unit and the second closed-loop network unit in the stent body are both formed by wave rod enclosure, wherein the enclosure area of ​​the first closed-loop network unit is larger than that of the second closed-loop network unit, so that the embedding efficiency of the thrombus and the thrombus removal efficiency can be improved.

[0042] (3) Furthermore, the stent body is provided with proximal development and distal development, respectively. Combined with the main body development, the stent body can achieve a full development effect at any time, so that the surgeon can achieve full body development of the stent body during the operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] Figure 1 A schematic diagram of the deployment structure of the stent of the present invention and a thrombus removal system including the stent is shown.

[0044] Figure 2 A schematic structural diagram of a stent according to an embodiment of the present invention and a stent in a thrombus removal system including the stent is shown.

[0045] Figure 3 A schematic structural diagram of a stent according to an embodiment of the present invention and a closed-loop network unit in a thrombus removal system including the stent is shown.

[0046] Figure 4 A schematic diagram showing the area relationship between the developing network unit and the closed-loop network unit in the stent according to an embodiment of the present invention and the thrombus removal system including the stent is shown.

[0047] Figure 5 A schematic diagram of a first winding path for main body visualization in a stent and a thrombectomy system including the stent according to an embodiment of the present invention is shown.

[0048] Figure 6 A schematic diagram of a second winding path for main body visualization in a stent and a thrombectomy system including the stent according to an embodiment of the present invention is shown.

[0049] Figure 7 A schematic diagram of a third winding path for main body visualization in a stent and a thrombectomy system including the stent according to an embodiment of the present invention is shown.

[0050] Figure 8 A schematic diagram of a fourth winding path for main body visualization in a stent and a thrombectomy system including the stent according to an embodiment of the present invention is shown.

[0051] Figure 9 A winding schematic diagram of a combination of a first winding path and a second winding path of a main body display in a stent and a thrombectomy system including the stent according to an embodiment of the present invention is shown.

[0052] Figure 10 A schematic diagram of a first winding path for main body visualization in a stent according to a second embodiment of the present invention and a thrombectomy system including the stent is shown.

[0053] Figure 11 A schematic diagram of a second winding path for main body visualization in a stent according to a second embodiment of the present invention and a thrombectomy system including the stent is shown.

[0054] Figure 12A schematic diagram of a third winding path for main body visualization in a stent according to a second embodiment of the present invention and a thrombectomy system including the stent is shown.

[0055] Figure 13 A schematic diagram of a fourth winding path for main body visualization in a stent according to a second embodiment of the present invention and a thrombectomy system including the stent is shown.

[0056] Figure 14 A schematic diagram of a fifth winding path for main body visualization in the stent and the thrombectomy system including the stent according to the second embodiment of the present invention is shown.

[0057] Figure 15 A schematic diagram of a sixth winding path for main body visualization in the stent and the thrombectomy system including the stent according to the second embodiment of the present invention is shown.

[0058] Figure 16 A schematic diagram showing a combination of a first winding path and a second winding path of a main body of a stent and a thrombectomy system including the stent according to a second embodiment of the present invention is shown.

[0059] Figure 17 A winding schematic diagram of a combination of a fifth winding path and a sixth winding path of a main body in a stent according to a second embodiment of the present invention and a thrombectomy system including the stent is shown.

[0060] Figure 18 A schematic diagram of a first winding path for main body visualization in a stent and a thrombectomy system including the stent according to a third embodiment of the present invention is shown.

[0061] Figure 19 A schematic diagram of a second winding path for main body visualization in a stent and a thrombectomy system including the stent according to a third embodiment of the present invention is shown.

[0062] Figure 20 A schematic diagram of a third winding path for main body visualization in a stent according to a third embodiment of the present invention and a thrombectomy system including the stent is shown.

[0063] Figure 21 A schematic diagram of a fourth winding path for main body visualization in a stent according to a third embodiment of the present invention and a thrombectomy system including the stent is shown.

[0064] Figure 22 A first structural schematic diagram of distal end visualization in a stent and a thrombectomy system including the stent according to an embodiment of the present invention is shown.

[0065] Figure 23 A cross-sectional view showing the distal end of a stent and a thrombectomy system including the stent according to an embodiment of the present invention is shown in the right side view.

[0066] Figure 24 A cross-sectional view of a stent according to an embodiment of the present invention and a thrombectomy system including the stent, with the distal end thereof being visualized in a front view, is shown.

[0067] Figure 25 A second structure diagram of the distal end visualization of the stent and the thrombectomy system comprising the stent is shown.

[0068] Figure 26 A second structure diagram of the distal end visualization of the stent and the thrombectomy system comprising the stent is shown.

[0069] Figure 27 A second structure diagram of the distal end visualization of the stent and the thrombectomy system comprising the stent is shown.

[0070] Figure 28 A second structure diagram of the distal end visualization of the stent and the thrombectomy system comprising the stent is shown.

[0071] Figure 29 A second structure diagram of the distal end visualization of the stent and the thrombectomy system comprising the stent is shown.

[0072] Figure 30 A third structure diagram of the distal end visualization of the stent and the thrombectomy system comprising the stent is shown.

[0073] Figure 31 A structure diagram of the proximal end visualization of the stent and the thrombectomy system comprising the stent is shown.

[0074] In the drawings, the following signs are marked: 1, distal end visualization; 101, first distal end visualization wire; 102, second distal end visualization wire; 103, third distal end visualization wire; 2, main body visualization; 201, first main body visualization wire; 202, second main body visualization wire; 203, third main body visualization wire; 3, proximal end visualization; 301, proximal end visualization wire; 4, stent body; 41, distal end part; 411, arc-shaped part; 42, middle part; 43, proximal end part; 430, first inclined slot wave pole; 431, second inclined slot wave pole; 400, first closed loop net unit; 4001, first long wave pole; 4002, first short wave pole; 4003, second long wave pole; 4004, second short wave pole; 401, second closed loop net unit; 4011, third short wave pole; 5, push rod. DETAILED DESCRIPTION

[0075] In order to make the objects, technical solutions and advantages of the present application clearer, the stent and the thrombus extraction system comprising the stent according to the present application are further described in detail below in combination with the drawings and specific embodiments. The advantages and features of the present application will be clearer according to the following description. It should be noted that the drawings are greatly simplified and all use non-precise proportions, only for the purpose of facilitating and clarifying the description of the embodiments of the present application. In order to make the objects, features and advantages of the present application more obvious and easy to understand, please refer to the drawings. It should be noted that the structures, proportions, sizes and the like shown in the drawings attached to the present specification are only used to cooperate with the content disclosed in the specification, so that those skilled in the art can understand and read, and are not used to limit the conditions for implementing the present application, so they do not have substantial technical significance. Any modification of structure, change of proportion relationship or adjustment of size, without affecting the effects and purposes that can be achieved by the present application, should still fall within the scope of the technical content disclosed by the present application.

[0076] As used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the content clearly dictates otherwise. The term "proximal" generally refers to the end closer to the operator, and the term "distal" generally refers to the end closer to the patient's lesion site. By way of example, Figure 1 the left side of the stent is the distal end, Figure 1 the right side of the stent is the proximal end. Figure 1

[0077] Embodiment One:

[0078] The specific structure of the stent is described as follows:

[0079] Please refer to Figure 1 and Figure 2 , the stent comprises a stent body 4 and a developing structure.

[0080] The stent body 4 is a cylindrical structure formed by at least one closed loop net unit coupled with each other, but is not limited to only a cylindrical structure, in other embodiments of the present application, it can be coupled to form a spherical structure, a wedge-shaped structure, a spindle-shaped structure, or any one or a combination of other irregular bodies, and the closed loop net unit is composed of a wave pole.

[0081] The developing structure comprises a main developing structure 2, the main developing structure 2 comprises at least one main developing wire, the main developing wire is wound along at least part of the wave pole of the stent body 4, preferably, the main developing wire is spirally wound on the wave pole, and the main developing wire is arranged from the proximal end to the distal end along the stent body 4 in the stent of the present embodiment one.

[0082] ​Correspondingly, in other embodiments of the present application, the main body developing wire can also be arranged from the distal end to the proximal end of the stent body 4, and the present application does not make any limitation in this regard.

[0083] The specific structure of the stent body 4 is described as follows:

[0084] Please continue to refer to Figure 1 and Figure 2 , the stent body 4 can be self-expanded along the longitudinal axis in the circumferential direction, and the stent body 4 comprises a distal end portion 41, an intermediate portion 42 and a proximal end portion 43 connected in sequence. The above-mentioned closed loop net unit comprises at least one first closed loop net unit 400 and at least one second closed loop net unit 401.

[0085] Specifically, the first closed loop net unit 400 is designed with large mesh, which enables the stent body 4 to effectively embed inside the thrombus when the thrombus is opened in the middle, and is not easy to cut the thrombus into small pieces or cut into small pieces, so as to facilitate the complete removal of the thrombus. Please refer to Figure 3 , the first closed loop net unit 400 can be a common mesh closed structure, and the shape of the mesh can be circular, rhombic, hexagonal, etc. In specific implementation, in order to further increase the flexibility and wall adhesion of the overall spiral structure of the stent body 4, the first closed loop net unit 400 comprises two first long wave rods 4001 and second long wave rods 4003 which are parallel to each other, and two first short wave rods 4002 and second short wave rods 4004 which are parallel to each other, wherein the first long wave rod 4001, the second long wave rod 4003, the first short wave rod 4002 and the second short wave rod 4004 form a quadrilateral structure.

[0086] Further, the second closed loop net unit 401 is designed with small mesh, which enables the stent body 4 to generate a larger radial support force when capturing the thrombus during the release process, which is beneficial to drag the thrombus when the stent body 4 is withdrawn, and the thrombus is not easy to fall off during the withdrawal process. Please refer to Figure 2 and Figure 3 , the second closed loop net unit 401 is also a mesh closed structure, and the shape of the mesh can be circular, rhombic, hexagonal, etc. In specific implementation, the second closed loop net unit 401 is surrounded by a plurality of third short wave rods 4011 to form a quadrilateral structure. Of course, if the second closed loop net unit 401 is adjacent to the first closed loop net unit 400, please refer to Figure 1 and Figure 2 , the second closed loop net unit 401 will share a wave rod or a part of a wave rod with the first closed loop net unit 400, and the shared wave rod can be any one of the first short wave rod 4002 and the second short wave rod 4004 of the first closed loop net unit 400, or it can be a part of any one of the first long wave rod 4001 and the second long wave rod 4003.

[0087] Further, the first closed loop net unit 400 encloses an area larger than the area enclosed by the second closed loop net unit 401. The arrangement of the large-mesh first closed loop net unit 400 and the small-mesh second closed loop net unit 401 can improve the embedding efficiency of thrombus and improve the thrombectomy efficiency.

[0088] Further, in the stent described in Embodiment One, the area enclosed by the first closed loop net unit 400 is 2-5 times the area enclosed by the second closed loop net unit 401, preferably, the area enclosed by the first closed loop net unit 400 is 2-4 times the area enclosed by the second closed loop net unit 401.

[0089] Further, in the stent described in Embodiment One, the number of the first closed loop net units 400 is 1 / 20-1 / 3 the number of the second closed loop net units 401. Preferably, the number of the first closed loop net units 400 is 1 / 14-1 / 4 the number of the second closed loop net units 401.

[0090] Further, please refer to Figure 2 , the stent body 4 further comprises a bevelled mouth wave pole arranged at an angle to the axis of the stent body 4, in the stent described in Embodiment One, the bevelled mouth wave pole is respectively a first bevelled mouth wave pole 430 and a second bevelled mouth wave pole 431.

[0091] The specific structure of the main body development 2 is described as follows:

[0092] Please refer to Figure 1 , the main body development 2 comprises a main body development wire, the main body development wire forms a development net unit on the path of winding the stent body 4 along the wave pole, the development net unit marks the structure and / or position of the stent.

[0093] Further, in the stent described in Embodiment One, the development net unit is a closed geometric shape. The area of the development net unit is the same as the area of the closed loop net unit of the stent body 4 at this position, wherein the area of the development net unit refers to the area enclosed by the main body development wire, and the area of the closed loop net unit specifically refers to the area enclosed by the wave pole. For example, please refer to Figure 5 , Figure 5 , the area enclosed by the first main body development wire 201 in the first main body development wire 201 is the area of the development net unit, and the area of the development net unit is the same as the area of the closed loop net unit of the stent body 4 at this position, i.e. the area enclosed by the wave pole (the area enclosed by the first long wave pole 4001, the first single-pole 4002, the second long wave pole 4003, and the second short wave pole 4004).

[0094] Further, the developing net unit marks the special position of the stent, the special position being any one or more of 1 / 3 or 1 / 2 or 2 / 3 of the total length of the stent. Marking the special position by the developing net unit can provide the operator with the position and posture of the stent, facilitating the operator to judge and operate.

[0095] Of course, in other embodiments of the present application, the area of the developing net unit can also be smaller than the area of the closed loop net unit of the stent body 4 at this position. Alternatively, please refer to Figure 4 As shown, the area of the developing net unit is the sum of the areas of several closed loop net units of the stent body 4 at this position.

[0096] Please refer to Figure 5 The main developing 2 is at least one first main developing wire 201 and is attached to all wave rods of at least one first closed loop net unit 400 in a winding manner and is attached to part of the wave rods of at least one second closed loop net unit 401 in a winding manner.

[0097] Further, please continue to refer to Figure 5 The winding direction of the first main developing wire 201 is from the proximal end of the stent body 4 to the distal end of the stent body 4. Specifically, the first main developing wire 201 winds from the proximal end of the first bevel wave rod 430 in the arrow direction, changes direction at the first bifurcation of the first bevel wave rod 430, and reaches the distal end of the stent body 4 after winding the three first closed loop net units 400 in turn. Specifically, the first main developing wire 201 winds the first closed loop net unit 400 one turn in the counterclockwise direction, and the winding path of the first main developing wire 201 is in the order of the first long wave rod 4001, the first short wave rod 4002, the second long wave rod 4003, and the second short wave rod 4004, wherein the first main developing wire 201 winds twice at the first long wave rod 4001 and enters the next first closed loop net unit 400 along the winding path. The first main developing wire 201 winds around all wave rods of the first closed loop net unit 400 to form a developing net unit, which can develop the first closed loop net unit 400, facilitating the operator to perform surgery.

[0098] Further, please continue to refer to Figure 5 When winding the next first closed loop net unit 400 after winding a first closed loop net unit 400, the first main developing wire 201 needs to wind a third short wave rod 4011 in the second closed loop net unit 401 in order to enter the winding path of the next first closed loop net unit 400.

[0099] Accordingly, in other embodiments of the present invention, the winding path of the first main developing wire 201 can be changed to obtain the following different winding paths:

[0100] Please refer to Figure 6 , Figure 6 A second winding path of the first main developing filament 201 in the main developing apparatus 2 is shown, wherein the first main developing filament 201 is again wound from the proximal end of the support body 4 to the distal end of the support body 4. The first main developing filament 201 begins winding along the arrow direction from the proximal end of the second beveled wave rod 431, changes direction at the first bifurcation of the second beveled wave rod 431, and sequentially winds around three first closed-loop network units 400 before reaching the distal end of the support body 4. Specifically, the first main developing filament 201 winds around all the wave rods of the first closed-loop network unit 400 in a clockwise direction, with the winding order being the second short wave rod 4004, the second long wave rod 4003, the first short wave rod 4002, and the first long wave rod 4001. The first main developing filament 201 is wound around the second short wave rod 4004 twice.

[0101] Please refer to Figure 7 , Figure 7 The third winding path of the first main developing filament 201 in the main developing apparatus 2 is shown. The first main developing filament 201 is again wound from the proximal end of the support body 4 to the distal end of the support body 4. The first main developing filament 201 is wound along the arrow direction from the proximal end to the middle portion of the first beveled wave rod 430. At the second bifurcation of the first beveled wave rod 430, the first main developing filament 201 changes direction and sequentially winds around three first closed-loop network units 400 before reaching the distal end of the support body 4. Specifically, the first main developing filament 201 is wound around all the wave rods of the first closed-loop network unit 400 in a clockwise direction, with the winding order being the second long wave rod 4003, the first short wave rod 4002, the first long wave rod 4001, and the second short wave rod 4004. The first main developing filament 201 is wound around the second long wave rod 4003 twice.

[0102] Please refer to Figure 8 , Figure 8The fourth winding path of the first main developing filament 201 in the main developing device 2 is shown, wherein the first main developing filament 201 is again wound from the proximal end of the support body 4 to the distal end of the support body 4. The first main developing filament 201 is wound along the arrow direction from the proximal end to the distal end of the second beveled wave rod 431. At the third bifurcation of the second beveled wave rod 431, the first main developing filament 201 changes direction and sequentially winds around three first closed-loop network units 400 before reaching the distal end of the support body 4. Specifically, the first main developing filament 201 is wound around all the wave rods of the first closed-loop network unit 400 in a counterclockwise direction. The winding order is first short wave rod 4002, second long wave rod 4003, second short wave rod 4004, and first long wave rod 4001. The first main developing filament 201 is wound around the first short wave rod 4002 twice.

[0103] Please refer to Figure 9 In other embodiments of the present invention, the main body developing 2 may also use more than one main body developing wire. Figure 9 The main body developing 2 includes a first main body developing filament 201 and a second main body developing filament 202, wherein the first main body developing filament 201 is Figure 5 The first main body developing wire 201 is wound in the first winding path, and the second main body developing wire 202 is wound in the first winding path. Figure 6 The second winding path shown is used for winding. The overlapping manner of the first main developing wire 201 and the second main developing wire 202 allows the position of the first closed-loop network unit 400 to be more clearly indicated, thereby facilitating the surgeon to perform surgery.

[0104] Correspondingly, in other embodiments of the present invention, the winding path of the main body developer 2 may also be as follows: Figures 5 to 8 Any combination thereof can be used as long as the position of the first closed-loop network unit 400 can be more clearly indicated to facilitate the operator in performing the operation.

[0105] Furthermore, the stent according to the first embodiment of the present invention may further include a distal imaging 1 and / or a proximal imaging 3, please refer to Figure 1 The distal end development 1 is fixed to the distal end of the stent body 4 , and the proximal end development is fixed to the proximal end of the stent body 4 .

[0106] The specific structure of the distal imaging 1 is described below:

[0107] Please refer to Figures 22 to 24In the stent described in Example 1 of the present invention, the distal imaging device 1 is sleeved on the distal wave rod of the stent body 4. The distal imaging device 1 comprises a first distal imaging filament 101 wound around the distal wave rod of the stent body 4 to form at least one layer of a wrapping structure. Specifically, in Example 1 of the present invention, the first distal imaging filament 101 is wound around the distal end of the stent body 4 in a proximal-to-distal direction (or vice versa) to form a single layer of a wrapping structure.

[0108] For further information, please refer to Figure 1 、 Figures 22 to 24 The proximal end of the distal imaging device 1 is integrally or detachably connected to the distal end of the main imaging device 2. When the proximal end of the distal imaging device 1 and the distal end of the main imaging device 2 are integrally connected, they are formed from the same imaging wire. When the proximal end of the distal imaging device 1 and the distal end of the main imaging device 2 are detachably connected, they can also be connected and fixed by bonding or winding. Of course, the proximal end of the distal imaging device 1 and the distal end of the main imaging device 2 can also be fixed by welding. In some embodiments, the distal imaging device 1 and the main imaging device 2 can also be independent of each other and not connected.

[0109] Of course, in other embodiments of the present invention, the first distal developing wire 101 can be wrapped around the distal wave rod of the stent body 4 from the proximal end to the distal end (or from the distal end to the proximal end of the stent body 4) for several turns to form a wrapping structure and then wrapped along the one wrapping structure for several turns to form a wrapping structure of two or more layers.

[0110] Furthermore, in other embodiments of the present invention, the distal end developer 1 can be fixed to the distal end of the stent body 4 by bonding, welding, or the like.

[0111] The specific structure of the proximal end development 3 is described below:

[0112] Please refer to Figure 1 and Figure 31 The proximal end developer 3 is connected to the proximal end of the stent body 4, wherein the proximal end developer 3 can be fixed to the proximal end of the stent body 4 by means of sleeve connection, winding, welding, or bonding, and the distal end of the proximal end developer 3 can be integrally connected or detachably connected to the proximal end of the main body developer 2. In the stent described in Example 1 of the present invention, the proximal end developer 3 uses a proximal end developer wire 301 and is wound around the proximal end of the stent body 4.

[0113] Furthermore, the number of developing filaments in the main body developing 2, the proximal end developing 3 and the distal end developing 1 can be 1 to 8, preferably 1 to 6.

[0114] Correspondingly, the present invention further provides a thrombus removal system, which includes the above-mentioned stent and a pushing rod 5 located at the proximal end of the stent, wherein the pushing rod 5 is non-coaxially arranged with the stent.

[0115] Furthermore, the proximal end development 3 is coaxially arranged with the proximal end of the stent, and the distal end development 1 is coaxially arranged with the distal end rod of the stent.

[0116] Furthermore, the proximal development 3, the main development 2 and the distal development 1 are made of developable materials, and the developable materials are any one or more combinations of tantalum, gold, platinum, platinum-iridium and platinum-tungsten.

[0117] Furthermore, the material of the stent body 4 can be any one of nickel-titanium alloy, cobalt-based alloy or stainless steel, which can be processed by cutting metal pipes.

[0118] Furthermore, the push rod 5 can be made of any one or more materials selected from stainless steel, cobalt-chromium-nickel alloy, or nickel-titanium alloy.

[0119] Of course, in other embodiments of the present invention, the push rod and the stent in the thrombectomy system can also be coaxially connected, the proximal development 3 and the proximal end of the stent can also be non-coaxially arranged, and the distal development 1 and the distal wave rod of the stent can also be non-coaxially arranged.

[0120] Example 2:

[0121] The bracket of the second embodiment of the present invention is basically the same as that of the first embodiment, and the same parts are not described again. Only the differences are described below.

[0122] The structure of the main body development 2 is described below:

[0123] In the bracket described in the second embodiment, the developing mesh unit can be a semi-open geometric shape or a closed geometric shape composed of semi-open geometric shapes. Specifically, the main developing 2 is at least one first main developing wire 201 wound around a portion of the corrugated rod of the first closed-loop mesh unit 400 and a portion of the corrugated rod wound around the second closed-loop mesh unit 401.

[0124] Please refer to Figure 10 , Figure 10The figure shows a first winding path of the first main developing filament 201 of the main developing device 2 in the second embodiment of the present invention. The first main developing filament 201 is again wound from the proximal end of the support body 4 to the distal end of the support body 4. The first main developing filament 201 starts at the proximal end (first bifurcation) of the second beveled wave rod 431 in the direction of the arrow, reverses direction, and sequentially winds around three first closed-loop network units 400 before reaching the distal end of the support body 4. Specifically, the first main developing filament 201 winds counterclockwise around some of the wave rods of the first closed-loop network unit 400, with the winding order being the first long wave rod 4001, the first short wave rod 4002, and the second long wave rod 4003.

[0125] Please continue to refer to Figure 10 When the first closed-loop network unit 400 is wound and the next first closed-loop network unit 400 is wound, the first main developing wire 201 passes through two third short-wave rods 4011 in sequence in this embodiment 2 so as to enter the next first closed-loop network unit 400 for winding.

[0126] Please refer to Figure 11 , Figure 11 The figure shows a second winding path for the first main developing filament 201 in the main developing device 2 of the second embodiment of the present invention. The first main developing filament 201 is again wound from the proximal end of the support body 4 to the distal end. The first main developing filament 201 is wound along the arrow direction from the proximal end to the distal end of the second beveled wave rod 431. At the third bifurcation of the second beveled wave rod 431, the filament changes direction and sequentially winds around three first closed-loop network units 400 before reaching the distal end of the support body 4. Specifically, the first main developing filament 201 is wound clockwise around some of the wave rods of the first closed-loop network unit 400, with the winding order being the first long wave rod 4001, the second short wave rod 4004, and the second long wave rod 4003.

[0127] Please continue to refer to Figure 11 When the first main developing yarn 201, after being wound in a first closed-loop mesh unit 400, needs to be wound in the next first closed-loop mesh unit 400, the first main developing yarn 201 in this second embodiment passes through two third short wave rods 4011 in sequence to enter the next first closed-loop mesh unit 400 for winding. Before the first main developing yarn 201 begins to wind around the first closed-loop mesh unit 400 at the distal end of the first beveled wave rod 430, it needs to pass through the second closed-loop mesh unit 401 and be wound around one of the third short wave rods 4011 therein.

[0128] Please refer to Figure 12 , Figure 12The third winding path of the first main body developing wire 201 in the second embodiment of the main body developing 2 is shown, wherein the first main body developing wire 201 is also wound from the proximal end of the stent body 4 to the distal end of the stent body 4, the first main body developing wire 201 is wound from the proximal end of the first bevelled wave rod 430 in the arrow direction, then reversed at the first bifurcation to sequentially wind three first closed loop net units 400 to reach the distal end of the stent body 4. Specifically, the first main body developing wire 201 winds the partial wave rod of the first closed loop net unit 400 in the clockwise direction, and the winding sequence is the second short wave rod 4004, the second long wave rod 4003 and the first short wave rod 4002 in turn.

[0129] Please continue to refer to Figure 12 When winding the next first closed loop net unit 400 after winding by a first closed loop net unit 400, the first main body developing wire 201 sequentially passes through a third short wave rod 4011 in this second embodiment to enter the next first closed loop net unit 400 for winding.

[0130] Please refer to Figure 13 , Figure 13 The fourth winding path of the first main body developing wire 201 in the second embodiment of the main body developing 2 is shown, wherein the first main body developing wire 201 is also wound from the proximal end of the stent body 4 to the distal end of the stent body 4, the first main body developing wire 201 is wound from the proximal end of the first bevelled wave rod 430 to the middle part of the first bevelled wave rod 430 in the arrow direction, then reversed at the second bifurcation of the first bevelled wave rod 430 to sequentially wind three first closed loop net units 400 to reach the distal end of the stent body 4. Specifically, the first main body developing wire 201 winds the partial wave rod of the first closed loop net unit 400 in the counterclockwise direction, and the winding sequence is the second short wave rod 4004, the first long wave rod 4001 and the first short wave rod 4002 in turn.

[0131] Please refer to Figure 14 , Figure 14 The fifth winding path of the first main body developing wire 201 in the second embodiment of the main body developing 2 is shown, wherein the first main body developing wire 201 is also wound from the proximal end of the stent body 4 to the distal end of the stent body 4, the first main body developing wire 201 is wound from the proximal end of the second bevelled wave rod 431 to the middle part of the second bevelled wave rod 431 in the arrow direction, then reversed at the second bifurcation of the second bevelled wave rod 431 to sequentially wind three first closed loop net units 400 to reach the distal end of the stent body 4. Specifically, the first main body developing wire 201 winds the partial wave rod of the first closed loop net unit 400 in the counterclockwise direction, and the winding sequence is 1 / 2 length of the first long wave rod 4001, the first short wave rod 4002 and 1 / 2 length of the second long wave rod 4003 in turn.

[0132] Please continue to refer to Figure 14 When the first main developing yarn 201 is wound around a first closed-loop mesh unit 400 and then needs to be wound around the next first closed-loop mesh unit 400, it passes through two third short-wave rods 4011 in sequence to enter the next first closed-loop mesh unit 400 for winding. Before the first main developing yarn 201 begins to wind around the first closed-loop mesh unit 400 at the middle portion of the second bevel-mouth wave rod 431, it passes through the second closed-loop mesh unit 401 and is wound around one of the third short-wave rods 4011 therein.

[0133] Correspondingly, in other embodiments of the present invention, the length of the first main developing wire 201 wrapped around the first long wave rod 4001 and the second long wave rod 4003 may also be more than 1 / 2 of the length. It may be 1 / 3 of the length, 1 / 4 of the length of the first long wave rod 4001 or the second long wave rod 4003, etc., as long as it can wrap around the first long wave rod 4001 and the second long wave rod 4003.

[0134] Please refer to Figure 15 , Figure 15 The sixth winding path of the first main developing wire 201 in the main developing 2 of the second embodiment of the present invention is shown. The sixth winding path is different from the above-mentioned fifth winding path in that the first main developing wire 201 is wound around part of the wave rods of the first closed-loop network unit 400 in a clockwise direction, and the winding order is winding the first long wave rod 4001 of 1 / 2 length, the second short wave rod 4004 and the second long wave rod 4003 of 1 / 2 length.

[0135] Please refer to Figure 16 , Figure 16 The first winding path of the main body development in the second embodiment of the present invention is shown (please refer to Figure 10 ) and the second winding path (see Figure 11 ) combination diagram, in Figure 16 The main body developing 2 uses a first main body developing wire 201 and a second main body developing wire 202, wherein the first main body developing wire 201 is Figure 10 In the second embodiment, the first winding path winds the bracket body 4, and the second main body developing wire 202 is wound around the bracket body 4. Figure 11 The second winding path of the embodiment 2 is used to wind the bracket body 4. Figure 16The first closed loop net unit 400 is surrounded by the first main developing wire 201 and the second main developing wire 202, wherein the first long wave rod 4001 and the second long wave rod 4003 in the first closed loop net unit 400 are respectively wound by the first main developing wire 201 and the second main developing wire 202, and the superimposed mode of the first main developing wire 201 and the second main developing wire 202 can clearly show the position of the first closed loop net unit 400, thereby facilitating the surgeon to perform the operation.

[0136] Please refer to Figure 17 , Figure 17 The fifth winding path (please refer to Figure 14 ) and the sixth winding path (please refer to Figure 15 ) of the main developing of the second embodiment of the application are shown in the schematic view, and in Figure 17 , the main developing 2 adopts the first main developing wire 201 and the second main developing wire 202, and the first closed loop net unit 400 is surrounded by the first main developing wire 201 and the second main developing wire 202, so that the position of the first closed loop net unit 400 can be clearly shown, thereby facilitating the surgeon to further perform the operation.

[0137] The specific structure of the distal developing 1 is described as follows:

[0138] Please refer to Figures 25 to 29 , in the stent of the second embodiment of the application, the distal developing 1 is the second distal developing wire 102 and the third distal developing wire 103 connected with the second distal developing wire 102, wherein the second distal developing wire 102 is wound on the arc-shaped part 411 of the distal end part 41 of the stent body 4 for several turns to obtain an axial ring, the proximal end of the third distal developing wire 103 is connected to the outside of the tail of the axial ring, and the third distal developing wire 103 is wound along the circumferential direction outside the axial ring to obtain a circumferential ring.

[0139] Embodiment three:

[0140] The stent of the third embodiment of the application is basically the same as the first embodiment or the second embodiment, and the same parts will not be described again, and only the different points will be described as follows.

[0141] The structure of the main developing 2 is described as follows:

[0142] Please refer to Figure 18 , the main developing 2 adopts the first main developing wire 201 and the second main developing wire 202, wherein the first main developing wire 201 is wound on the first long wave rod 4001 according to Figure 11In the second embodiment, the main body development is wound in a second winding path, and the second main body development wire 202 is wound in a spiral path from the proximal end of the bracket body 4 to the distal end of the bracket body 4. In this embodiment, the first short wave rod 4002 in the first closed-loop network unit 400 is not wound by the first main body development wire 201, but the first short wave rod 4002 is wound by the second main body development wire 202, so that the first closed-loop network unit 400 is surrounded and wound by the first main body development wire 201 and the second main body development wire 202. The overlapping manner of the first main body development wire 201 and the second main body development wire 202 makes the position of the first closed-loop network unit 400 clearly indicated, which is beneficial for the surgeon to perform surgery.

[0143] For further information, please refer to Figure 19 In other embodiments of the present invention, the main body developing 2 uses a first main body developing wire 201 and a second main body developing wire 202, wherein the first main body developing wire 201 is arranged according to Figure 6 In Example 1, the main body developer 2 is wound in the second winding path, and the second main body developer wire 202 is wound in a spiral path from the proximal end of the bracket body 4 to the distal end of the bracket body 4. Similarly, the first closed-loop network unit 400 is surrounded and wound by the first main body developer wire 201, and the second main body developer wire 202 is repeatedly wound at the first short-wave rod 4002. The superposition of the first main body developer 201 wire and the second main body developer wire 202 makes the position of the first closed-loop network unit 400 more clearly indicated, which is beneficial for the surgeon to perform surgery.

[0144] For further information, please refer to Figure 20 In other embodiments of the present invention, the second main body developing wire 202 and Figure 19 The second main body developing wire 202 is wound in a spiral path from the proximal end of the stent body 4 to the distal end of the stent body 4, and the first main body developing wire 201 is wound in a spiral path. Figure 5 In the first embodiment, the main body developer 2 is wound along the first winding path.

[0145] For further information, please refer to Figure 21 In other embodiments of the present invention, the main body developing 2 can use three main body developing wires, namely the first main body developing wire 201, the second main body developing wire 202 and the third main body developing wire 203, wherein the first main body developing wire 201 is also Figure 5 In Example 1, the main body developing wire 202 is wound along the first winding path, and the second main body developing wire 202 changes direction at the middle part of the first bevel wave rod 430 (i.e., the second bifurcation) and is wound from the proximal end of the bracket body 4 to the distal end of the bracket body 4 in a spiral path. The third main body developing wire 203 changes direction at the distal end of the first bevel wave rod 430 (i.e., the third bifurcation) and is also wound from the proximal end of the bracket body 4 to the distal end of the bracket body 4 in a spiral path.

[0146] In other embodiments of the present invention, the main developing filaments 2 may include 1 to 8 main developing filaments. In an embodiment including multiple main developing filaments, the main developing filaments may be combined in any one of the combinations of Embodiments 1 to 3.

[0147] Please refer to Figure 30 The distal development 1 in the third embodiment of the present invention also adopts the first distal development wire 101, wherein the first distal development wire 101 is tightly wound several times and forms an axial ring on the arc portion 411 of the distal end portion 41 of the bracket body 4, wherein the inner surface of the axial ring is in contact with the outer side of the arc portion 411.

[0148] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0149] The above-described embodiments merely illustrate several implementations of the present invention, and while their descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent. It should be noted that a person skilled in the art would be able to make numerous variations and improvements without departing from the spirit of the present invention, all of which fall within the scope of protection of the present invention. Therefore, the scope of protection of the patent for this invention shall be determined by the appended claims.

Claims

1. A bracket, characterized in that: The stent includes a stent body and a developing structure, wherein the stent body is formed by coupling at least one closed-loop network unit with each other, and the closed-loop network unit is formed by enclosing a wave rod. The developing structure includes a main developing body, and the main developing body has at least one main developing wire, and the main developing wire is wound around at least a portion of the stent body along the wave rod; The main body developing wire forms a developing net unit along the path of the wave rod winding around the stent body, and the developing net unit marks the structure and / or position of the stent; The developing web unit is a closed geometric shape; or, The developing screen unit is in a semi-open geometric shape; The main developing wire is arranged along the proximal end to the distal end of the stent body or along the distal end to the proximal end of the stent body; The closed-loop network unit includes at least one first closed-loop network unit and at least one second closed-loop network unit, and the area enclosed by the first closed-loop network unit is larger than the area enclosed by the second closed-loop network unit; The main developing wire is attached to at least one of the first closed-loop net units in a winding manner, so as to enable at least one of the first closed-loop net units to be developed on the bracket body.

2. The bracket according to claim 1, wherein: The main developing wire is spirally wound around the wave rod.

3. The bracket according to claim 1, wherein: The area of ​​the developing web unit is the same as the area of ​​the closed loop web unit of the support body at this position; or, The area of ​​the developing web unit is the sum of the areas of a plurality of the closed-loop web units at the position of the support body.

4. The bracket according to claim 1, wherein: The area enclosed by the first closed-loop network unit is 2 to 5 times the area enclosed by the second closed-loop network unit.

5. The bracket according to claim 1, wherein: The number of the first closed-loop network units is 1 / 20 to 1 / 3 of the number of the second closed-loop network units.

6. The bracket according to claim 1, wherein: The main developing wire is wound around all the corrugated rods of at least one first closed-loop network unit and is wound around part of the corrugated rods of at least one second closed-loop network unit.

7. The bracket according to claim 1, wherein: At least one of the first closed-loop network units has a portion of wave rods wound by the main developing wire at least twice.

8. The bracket according to claim 1, wherein: The main developing wire is wound around a portion of the corrugated rods of at least one of the first closed-loop network units and is wound around a portion of the corrugated rods of at least one of the second closed-loop network units.

9. The bracket according to claim 1, wherein: The number of the main developing wires is at least two, one of which is wound around part of the wave rods of at least one of the first closed-loop network units and part of the wave rods of at least one of the second closed-loop network units, and the other is wound around the remaining wave rods of at least one of the first closed-loop network units and part of the wave rods of at least one of the second closed-loop network units.

10. The bracket according to claim 1, wherein: The number of the main developing filaments is 1 to 8.

11. The bracket according to claim 1, wherein: The development structure further includes a distal development, and the distal development is connected to the distal end of the stent body.

12. The bracket according to claim 11, wherein: The proximal end of the distal end development is integrally connected to the distal end of the main body development or is detachably connected thereto.

13. The bracket according to claim 11, wherein: The distal end development is that the first distal end development wire is wound around the distal end wave rod of the stent body to form at least one layer of wrapping structure.

14. The bracket according to claim 11, wherein: The distal development is a second distal development wire, which is wound around the distal wave rod of the stent body to form an axial ring and around the outer side of the axial ring to form a circumferential ring.

15. The bracket according to claim 1, wherein: The development structure further includes a proximal development device connected to the proximal end of the stent body.

16. The bracket according to claim 15, wherein: The distal end of the proximal end development is integrally connected to the proximal end of the main body development or is detachably connected thereto.

17. Thrombectomy system, characterized by: The thrombus removal system comprises the stent according to any one of claims 1 to 16 and a pushing rod disposed at the proximal end of the stent, wherein the pushing rod is coaxial or non-coaxial with the stent.

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