An intelligent cryogenic refrigerator for storing biological samples

Abstract

The present invention discloses an intelligent cryogenic refrigerator for storing biological samples, comprising: a heat preservation box housing, two groups of rotary cylinder storage racks, a rotary cylinder driving mechanism, a gripper, a gripper lifting driving mechanism, a gripper handling driving mechanism, and a safety heat preservation door arranged on the front of the heat preservation box housing. A test tube rack access opening is arranged on the safety heat preservation door. The rotary cylinder storage rack comprises an inner rotary cylinder storage rack and an outer rotary cylinder storage rack which are concentrically arranged. The rotary cylinder driving mechanism is arranged above the top plate of the heat preservation box housing and comprises an inner rotary cylinder driving component for driving the inner rotary cylinder storage rack to rotate forward or backward and an outer rotary cylinder driving component for driving the outer rotary cylinder storage rack to rotate forward or backward. The gripper handling driving mechanism is used for driving the rotation and telescoping of the gripper to grasp the test tube racks in the inner rotary cylinder storage rack and the outer rotary cylinder storage rack. An intelligent cryogenic refrigerator for storing biological samples according to the present invention can realize the automatic access of a single test tube rack, effectively improving the working efficiency.

Description

Technical Field

[0001] The present invention relates to the technical field of cryogenic storage, and particularly to an intelligent ultra-low temperature refrigerator for storing biological samples. Background Art

[0002] At present, -80°C low-temperature storage refrigerators are mainly used in application scenarios with a small sample volume or low investment. Currently, the storage operation and management of samples in low-temperature refrigerators are mainly carried out manually. The traditional storage method requires opening the refrigerator door, which affects the temperature and humidity environment inside the refrigerator, thus affecting the storage safety of biological samples. Summary of the Invention

[0003] The main technical problem to be solved by the present invention is to provide an intelligent ultra-low temperature refrigerator for storing biological samples, which realizes the accuracy and efficiency of automated sample storage operations and has an absolute advantage over manual operation of refrigerator management of samples.

[0004] To solve the above technical problem, a technical solution adopted by the present invention is: an intelligent ultra-low temperature refrigerator for storing biological samples, comprising: a thermal insulation box housing, two sets of rotary storage racks for storing test tube racks arranged inside the thermal insulation box housing, a rotary drive mechanism, a gripper for picking and placing test tube racks, a gripper lifting drive mechanism, a gripper handling drive mechanism arranged on the gripper lifting drive mechanism, and a safety thermal insulation door arranged on the front of the thermal insulation box housing. A test tube rack access opening is arranged on the safety thermal insulation door. The rotary storage rack comprises a concentrically arranged inner rotary storage rack and an outer rotary storage rack. The rotary drive mechanism is arranged above the top plate of the thermal insulation box housing and comprises an inner rotary drive assembly for driving the inner rotary storage rack to rotate forward or backward and an outer rotary drive assembly for driving the outer rotary storage rack to rotate forward or backward. The gripper handling drive mechanism is used to drive the rotation and telescoping of the gripper to grab the test tube racks in the inner rotary storage rack and the outer rotary storage rack.

[0005] In a preferred embodiment of the present invention, the inner rotary storage rack and the outer rotary storage rack have the same structure, including a rotary cylinder, cryogenic storage racks wound around the rotary cylinder in layers along the circumferential direction of the rotary cylinder, and test tube racks arranged in a plurality of cryogenic storage racks. The side plates on both sides of the cryogenic storage rack are fixedly connected to the upper and lower plates of the rotary cylinder. The cryogenic storage rack is a sheet metal part. The gap between the upper and lower adjacent layers of test tube racks in the cryogenic storage rack is close to 8MM.

[0006] In a preferred embodiment of the present invention, a group of spaces are vacated from a plurality of cryogenic storage racks distributed in a ring shape in the outer rotary storage rack to form a feeding station, so as to facilitate the gripper to grab the test tube racks in the cryogenic storage racks on the inner rotary storage rack.

[0007] In a preferred embodiment of the present invention, the gripper lifting drive mechanism includes a lifting column disposed within the insulation box housing, a ball screw module disposed on the lifting column, a guiding slide rail disposed on the side of the lifting column, and a fixing plate connected to the slider on the slide rail. The ball screw module is connected to the fixing plate and can drive the fixing plate to perform lifting motion.

[0008] In a preferred embodiment of the present invention, the gripper handling drive mechanism includes a bottom plate connected to the fixing plate, a rotation drive mechanism, and a multi-stage telescopic material taking mechanism. The gripper is disposed on the multi-stage telescopic material taking mechanism. The rotation drive mechanism is disposed below the multi-stage telescopic material taking mechanism and can drive the multi-stage telescopic material taking mechanism to rotate to facilitate the gripper to grasp the test tube racks in different directions.

[0009] In a preferred embodiment of the present invention, the multi-stage telescopic material taking mechanism includes a first turntable plate, a second telescopic plate, a third telescopic plate, and a swing arm drive assembly. The second telescopic plate is slidably connected to the first turntable plate through a first slide rail. The third telescopic plate is slidably connected to the second turntable plate through a second slide rail. Chain wheel and chain assemblies are respectively disposed on both sides of the second telescopic plate. The swing arm drive assembly includes a swing arm drive motor disposed on the first turntable plate and a swing arm. One end of the swing arm is connected to the swing arm drive motor, and the other end is disposed in the chute below the second telescopic plate. The swing arm drive motor can drive the extension and retraction movements of the second telescopic plate and the third telescopic plate.

[0010] In a preferred embodiment of the present invention, the chain wheel and chain assemblies include chain wheels diagonally disposed on both sides of the second telescopic plate and a chain A wound around the chain wheels. One end of the chain A is connected to the first turntable plate, and the other end of the chain A is connected to the third telescopic plate.

[0011] In a preferred embodiment of the present invention, the rotation drive mechanism includes a turntable drive motor disposed on the bottom plate. The output end of the turntable drive motor is connected to a rotating shaft disposed below the first turntable plate through a belt.

[0012] In a preferred embodiment of the present invention, the inner cylinder drive assembly includes a first worm drive motor disposed above the top plate of the insulation box housing and a first worm connected to the first worm drive motor. The first worm meshes with a first gear at the top of the rotating shaft of the inner cylinder storage rack. The outer cylinder drive assembly includes a second worm drive motor disposed above the top plate of the insulation box housing and a second worm connected to the second worm drive motor. The second worm meshes with a second gear at the top of the rotating shaft of the outer cylinder storage rack.

[0013] In a preferred embodiment of the present invention, the inner drum drive assembly and the outer drum drive assembly are both connected to a manual drum drive assembly, and the manual drum drive assembly includes a parallel axis fixing frame and a parallel axis rotatably arranged on the parallel axis fixing frame, and one end of the parallel axis is connected to one end of the first worm gear through a chain B.

[0014] In a preferred embodiment of the present invention, the test tube rack entrance and exit includes an outer sealed door arranged on the front of the safety insulation door and an inner sealed sliding door arranged on the back of the safety insulation door. The safety insulation door is also provided with a door body structure consisting of functions such as an automatic holding station, a defrosting station, a dehumidification suction station, an image acquisition station and a touch screen. The interior of the safety insulation door is filled with insulation material, and a sealing strip is provided between the safety insulation door and the insulation box shell to ensure sealing.

[0015] The beneficial effects of the present invention are as follows: the present invention has two groups of rotary drum storage racks, each group of rotary drum storage racks is divided into two sets of independently movable inner and outer rotary drum storage racks, the gripper interacts with the rotation of the rotary drum storage rack through the lifting and rotating functions, so as to grasp any group of test tube racks on the freezing racks of the inner and outer rotary drum storage racks on the left and right sides, and the gripper cooperates with the multi-stage telescopic material retrieval mechanism to grasp the test tube racks with double depth, occupies less space, and can extend the secondary telescopic plate and the tertiary telescopic plate in turn according to the actual transportation space, is easy to use, can realize fully automatic low-temperature storage and retrieval operation of biological samples, and effectively improve work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative work, among which:

[0017] Figure 1 It is a structural schematic diagram of an intelligent deep low temperature refrigerator for storing biological samples of the present invention;

[0018] Figure 2 yes Figure 1 Enlarged view of the circled area;

[0019] Figure 3 It is a structural schematic diagram of a gripper lifting drive mechanism and a gripper transport drive mechanism in an intelligent deep-low temperature refrigerator for storing biological samples of the present invention;

[0020] Figure 4 It is a schematic diagram of a gripper transport drive mechanism in an intelligent deep-low temperature refrigerator for storing biological samples of the present invention when it is in an extended state;

[0021] Figure 5 It is a schematic diagram of part of the structure of the gripper handling drive mechanism in the extended state in an intelligent cryogenic refrigerator for storing biological samples according to the present invention;

[0022] Figure 6 It is a schematic diagram during the movement of the gripper handling drive mechanism in an intelligent cryogenic refrigerator for storing biological samples according to the present invention;

[0023] Figure 7 It is a schematic diagram of the gripper handling drive mechanism in the retracted state in an intelligent cryogenic refrigerator for storing biological samples according to the present invention;

[0024] Figure 8 It is a schematic diagram of the structure of the safety thermal insulation door in an intelligent cryogenic refrigerator for storing biological samples according to the present invention;

[0025] Figure 9 It is a schematic diagram of the structure of the rotary cylinder storage rack in an intelligent cryogenic refrigerator for storing biological samples according to the present invention. Detailed implementation manners

[0026] Next, the technical solutions in the embodiments of the present invention will be described clearly and completely. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts belong to the scope of protection of the present invention.

[0027] Please refer to Figure 1-3 , an embodiment of the present invention: an intelligent cryogenic refrigerator for storing biological samples, including: a thermal insulation box housing 1, two groups of rotary cylinder storage racks 2 for storing test tube racks arranged in the thermal insulation box housing, a rotary cylinder drive mechanism, a gripper 4 for picking and placing test tube racks, a gripper lifting drive mechanism 5, a gripper handling drive mechanism 6 arranged on the gripper lifting drive mechanism, and a safety thermal insulation door 7 arranged on the front of the thermal insulation box housing. Among them, the thermal insulation box housing is made of environmentally friendly foamed thermal insulation material, a thermal insulation layer 8 is arranged on the top plate of the thermal insulation box housing, and a storage area of -80 °C is provided in the thermal insulation box housing. The top of the device is separated by a heat insulation layer to ensure that the heat generated by the device and the cold in the storage area cancel each other out, thereby optimizing the sample storage environment and ensuring the safety of the samples.

[0028] As Figure 8As shown, the surface of the safety insulation door is a toughened glass panel. There is a test tube rack access opening on the safety insulation door to ensure that the samples inside the equipment will not be affected during the sample access process. According to production requirements, the test tube rack access opening includes an outer sealing door 81 provided on the front of the safety insulation door and an inner sealing sliding door 82 provided on the back of the safety insulation door. An automatic clamping station 83, a defrosting station 84, a dehumidifying and air suction station 85, an image acquisition station 86, and a touch screen 87 are also provided on the safety insulation door. The automatic clamping station uses two grippers installed on both sides to perform a clamping action. The image acquisition station uses a QR code camera for taking pictures to capture the position compensation of the test tube rack, making the grasping work safer and more effective. For the test tubes of the incoming samples, which may be frosted due to contact with the external humid environment, a special defrosting function can also be designed. The defrosting station uses an alcohol spraying device in the existing technology to complete the cleaning function of the test tube rack, by cleaning the test tubes and the bottom of the test tube rack, so as to make the subsequent picture taking and code reading more accurate and efficient. The dehumidifying and air suction station uses the method of pumping air or blowing nitrogen to complete the dehumidifying function.

[0029] As Figure 9As shown, the drum storage rack includes an inner drum storage rack 21 and an outer drum storage rack 22 which are arranged concentrically. The drum driving mechanism is arranged above the top plate of the heat preservation box shell, including an inner drum driving assembly 31 for driving the inner drum storage rack to rotate forward or reversely, and an outer drum driving assembly 32 for driving the outer drum storage rack to rotate forward or reversely. The gripper transport driving mechanism is used to drive the rotation and extension of the gripper to grab the test tube racks in the inner drum storage rack and the outer drum storage rack. The movement trajectory of the gripper is within the range of the inscribed circle formed by the inner and outer drum mechanisms and the entrance and exit of the test tube rack. The center of the inscribed circle is the rotation center of the gripper. The inner drum storage rack and the outer drum storage rack have the same structure, including a drum 211, and a plurality of rollers arranged in layers around the circumference of the drum. The freezing rack 212 and the test tube racks arranged in several freezing racks, the side panels on both sides of the freezing rack are fixedly connected to the upper and lower plates of the rotating drum, the freezing rack is a sheet metal part, the gap between the test tube racks in the freezing rack is close to 8MM, the rotating shaft of the inner ring and the outer ring of the inner rotating drum storage rack is a round tube, and the inner and outer sides can be rotated at different angles through bearing connection. Several freezing racks distributed in a ring shape in the outer rotating drum storage rack have a group of spaces to form a material retrieval station 15, so as to facilitate the gripper to grab the test tube rack in the freezing rack on the inner rotating drum storage rack. The gripper can achieve double-depth grabbing. The setting of the inner and outer two-layer rotating drum storage racks can store more biological samples. Compared with the previous single-layer freezing rack form, the double-layer storage has a great advantage and saves more volume. Specifically, the inner drum drive assembly includes a first worm drive motor 311 arranged above the top plate of the insulation box shell and a first worm 312 connected to the first worm drive motor, the first worm is meshed with a first gear 313 at the top of the shaft of the inner drum storage rack; the outer drum drive assembly includes a second worm drive motor 321 arranged above the top plate of the insulation box shell and a second worm 322 connected to the second worm drive motor, the second worm is meshed with a second gear 323 at the top of the shaft of the outer drum storage rack, the inner drum drive assembly and the outer drum drive assembly are both connected to a manual drum drive assembly, the manual drum drive assembly includes a parallel shaft fixing frame 9 and a parallel shaft 10 rotatably arranged on the parallel shaft fixing frame, one end of the parallel shaft is connected to one end of the first worm through a chain B 11 transmission, which can be used to manually rotate the internal drum storage rack, and is used for manually rotating the drum storage rack when a power outage occurs.

[0030] like Figure 3As shown in the figure, the gripper lifting drive mechanism includes a lifting column 51 disposed inside the incubator housing, a ball screw module 52 disposed on the lifting column, a guide rail 53 disposed on the side of the lifting column, and a fixing plate 54 connected to the slider on the rail. The ball screw module is connected to the fixing plate and can drive the fixing plate to move up and down. The gripper handling drive mechanism includes a bottom plate 601 connected to the fixing plate, a rotation drive mechanism, and a multi-stage telescopic material taking mechanism. The gripper is disposed on the multi-stage telescopic material taking mechanism. The rotation drive mechanism is disposed below the multi-stage telescopic material taking mechanism and can drive the multi-stage telescopic material taking mechanism to rotate to facilitate the gripper to grasp the test tube racks in different directions. The rotation drive mechanism includes a turntable drive motor 602 disposed on the bottom plate. The output end of the turntable drive motor is connected to a rotating shaft 613 disposed below the first-stage turntable plate through a belt 603. Through the interaction of the lifting and rotation functions with the rotation of the rotary storage rack, any group of test tube racks on the inner and outer circles of the left and right sides of the frozen storage rack can be grasped.

[0031] As Figure 4-7 shown in the figure, the multi-stage telescopic material taking mechanism includes a first-stage turntable plate 604, a second-stage telescopic plate 605, a third-stage telescopic plate 606, and a swing arm drive assembly. The second-stage telescopic plate is slidably connected to the first-stage turntable plate through a first slide rail 607. The third-stage telescopic plate is slidably connected to the second-stage turntable plate through a second slide rail 608. Chain and sprocket assemblies are respectively disposed on both sides of the second-stage telescopic plate. The swing arm drive assembly includes a swing arm drive motor 609 disposed on the first-stage turntable plate and a swing arm 600. One end of the swing arm is connected to the swing arm drive motor, and the other end is disposed in a chute 610 below the second-stage telescopic plate. The swing arm drive motor can drive the swing arm to swing back and forth to drive the extension and retraction movements of the second-stage telescopic plate and the third-stage telescopic plate.

[0032] Specifically, the chain and sprocket assembly includes sprockets 611 disposed diagonally on both sides of the second-stage telescopic plate and a chain A 612 wound around the sprockets. One end of the chain A is connected to the first-stage turntable plate, and the other end of the chain A is connected to the third-stage telescopic plate. The gripper 12 is installed at the front end of the third-stage telescopic plate. Test tube rack guide plates 13 are also disposed on both sides of the gripper. The drive motor drives the swing arm to swing towards the rotary storage rack, driving the second-stage telescopic plate to move towards the rotary storage rack. Through the cooperation of the sprockets and the chain, the third-stage telescopic plate can be driven to move towards the rotary storage rack to support the test tube rack 14 in the frozen storage rack. The setting of the multi-stage telescopic material taking mechanism enables the second-stage telescopic plate and the third-stage telescopic plate to slide and extend simultaneously, facilitating the support and transportation of the test tube rack. After the test tube racks in the outer rotary storage rack are taken and placed, it can further retract inward to take materials from the inner rotary frozen storage rack, and can realize double-depth grasping of the test tube rack.

[0033] The beneficial effects of the intelligent cryogenic refrigerator for storing biological samples of the present invention are:

[0034] 1. The setting of two groups of rotary drum storage racks has great advantages in terms of storage capacity compared with the previous single-layer freezing storage rack form. Each group of rotary drum storage racks is divided into an inner ring and an outer ring of two sets of independently moving inner and outer rotary drum storage racks. The gripper interacts with the rotation of the rotary drum storage rack through lifting and rotating functions to achieve grasping any set of test tube racks on the freezing storage racks in the inner and outer rotary drum storage racks on the left and right sides. The gripper cooperates with a multi-stage telescopic feeding mechanism to be able to grasp test tube racks in double-depth. The moving parts for sample in and out of the warehouse are few, with high efficiency and relatively small occupied space. The secondary telescopic plate and the tertiary telescopic plate can be extended in sequence according to the actual transportation space, which is convenient to use. It can realize fully automatic low-temperature access operation of biological samples, effectively improving work efficiency.

[0035] 2. The rotary drum drive mechanism of the worm and worm gear is also connected to a set of external manual rotary drum drive components, which can be used for manual rotation of the internal storage rack for operation of manually rotating the storage rack in case of power failure.

[0036] 3. The automatic function area at the entrance and exit of the test tube rack is integrated into an actually openable invisible sealed safety insulation door. This area is integrated with two sealed doors for internal and external interaction. The inner door automatically opens and closes corresponding to the internal gripper's picking and placing tasks, and the outer door corresponds to external operators or other automated equipment. When receiving a task instruction, the sealed door automatically opens and closes. The two sealed doors are ensured not to open simultaneously to ensure that the low-temperature environment of the samples inside the equipment will not be affected during the sample in and out process, optimizing the sample storage environment and ensuring sample safety. The insulation door is also provided with an automatic clamping station. When the test tube rack for in and out of the warehouse is placed at this station, the two positioning blocks will have a slight clamping as the secondary positioning of the test tube rack to ensure the accuracy of picking the test tube rack. There is a hidden nozzle at the bottom of the clamping station. When the incoming test tube rack from the outside cannot be recognized by bottom photographing identification, the hidden nozzle automatically slides to the bottom of the test tube for spraying defrosting, and at the same time, the top exhaust fan starts to extract the internal gas to ensure the high efficiency of sample in and out of the warehouse.

[0037] The above are only the embodiments of the present invention, and thus do not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the content of the specification of the present invention, or directly or indirectly applied in other related technical fields, shall be equally included in the patent protection scope of the present invention.

Claims

1. An intelligent cryogenic refrigerator for storing biological samples, characterized in that, it includes: a thermal insulation box housing, two groups of rotary storage racks for storing test tube racks arranged inside the thermal insulation box housing, a rotary driving mechanism, a gripper for picking and placing test tube racks, a gripper lifting driving mechanism, a gripper handling driving mechanism arranged on the gripper lifting driving mechanism, and a safety thermal insulation door arranged on the front of the thermal insulation box housing. A test tube rack access opening is arranged on the safety thermal insulation door. The rotary storage rack includes an inner rotary storage rack and an outer rotary storage rack arranged concentrically. The rotary driving mechanism is arranged above the top plate of the thermal insulation box housing and includes an inner rotary driving component for driving the inner rotary storage rack to rotate forward or backward and an outer rotary driving component for driving the outer rotary storage rack to rotate forward or backward. The gripper handling driving mechanism is used to drive the rotation and telescoping of the gripper to grab the test tube racks in the inner rotary storage rack and the outer rotary storage rack. The inner rotary storage rack and the outer rotary storage rack have the same structure, including a rotary cylinder, cryogenic storage racks wound around the rotary cylinder in layers along the circumferential direction, and test tube racks arranged in a number of cryogenic storage racks. The side plates on both sides of the cryogenic storage rack are fixedly connected to the upper and lower plates of the rotary cylinder. The cryogenic storage rack is a sheet metal part. The gap between the upper and lower adjacent layers of test tube racks in the cryogenic storage rack is close to 8MM. The gripper lifting driving mechanism includes a lifting column arranged inside the thermal insulation box housing, a ball screw module arranged on the lifting column, a guiding slide rail arranged on the side of the lifting column, and a fixing plate connected to the slider on the slide rail. The ball screw module is connected to the fixing plate and can drive the fixing plate to move up and down. The gripper handling driving mechanism includes a bottom plate connected to the fixing plate, a rotary driving mechanism, and a multi-stage telescopic material taking mechanism. The gripper is arranged on the multi-stage telescopic material taking mechanism. The rotary driving mechanism is arranged below the multi-stage telescopic material taking mechanism and can drive the multi-stage telescopic material taking mechanism to rotate to facilitate the gripper to grab test tube racks in different directions. The rotary driving mechanism includes a turntable driving motor arranged on the bottom plate. The output end of the turntable driving motor is connected to a rotating shaft arranged below the multi-stage telescopic material taking mechanism through a belt. The test tube rack access opening includes an outer sealing door arranged on the front of the safety thermal insulation door and an inner sealing sliding door arranged on the back of the safety thermal insulation door. An automatic clamping station, a defrosting station, a dehumidifying and air suction station, an image acquisition station, and a touch screen are also arranged on the safety thermal insulation door. A sealing strip is arranged between the safety thermal insulation door and the thermal insulation box housing to ensure sealing.

2. The intelligent cryogenic refrigerator for storing biological samples according to claim 1, characterized in that, a group of spaces are vacated in a ring-shaped distribution among a number of cryogenic storage racks in the outer rotary storage rack to form a material taking station, so as to facilitate the gripper to grab the test tube racks in the cryogenic storage racks on the inner rotary storage rack.

3. The intelligent cryogenic refrigerator for storing biological samples according to claim 1, characterized in that, The multi-stage telescopic material-grabbing mechanism includes a primary turntable plate, a secondary telescopic plate, a tertiary telescopic plate and a swing arm driving assembly. The secondary telescopic plate is slidably connected to the primary turntable plate via a first slide rail, and the tertiary telescopic plate is slidably connected to the secondary turntable plate via a second slide rail. Sprocket chain assemblies are respectively provided on both sides of the secondary telescopic plate. The swing arm driving assembly includes a swing arm driving motor and a swing arm provided on the primary turntable plate. One end of the swing arm is connected to the swing arm driving motor, and the other end is provided in a slide groove below the secondary telescopic plate. The swing arm driving motor can drive the extension and retraction movements of the secondary telescopic plate and the tertiary telescopic plate.

4. An intelligent deep-low temperature refrigerator for storing biological samples according to claim 3, It is characterized in that The sprocket chain assembly includes sprockets diagonally arranged on both sides of the secondary telescopic plate and a chain A wound around the sprockets, one end of the chain A is connected to the primary turntable plate, and the other end of the chain A is connected to the tertiary telescopic plate.

5. The intelligent deep-low temperature refrigerator for storing biological samples according to claim 1, It is characterized in that The inner drum drive assembly includes a first worm drive motor arranged above the top plate of the insulation box shell and a first worm connected to the first worm drive motor, the first worm being meshed with a first gear at the top of the rotating shaft of the inner drum storage rack; the outer drum drive assembly includes a second worm drive motor arranged above the top plate of the insulation box shell and a second worm connected to the second worm drive motor, the second worm being meshed with a second gear at the top of the rotating shaft of the outer drum storage rack.

6. An intelligent deep-low temperature refrigerator for storing biological samples according to claim 5, It is characterized in that The inner drum drive assembly and the outer drum drive assembly are both connected to a manual drum drive assembly, and the manual drum drive assembly includes a parallel axis fixing frame and a parallel axis rotatably arranged on the parallel axis fixing frame, and one end of the parallel axis is connected to one end of the first worm gear through a chain B transmission.

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