Kit on-line loading and automatic changeover system and method

Abstract

The present application relates to the technical field of analyzers, in particular to a kit online loading and automatic replacement system and method. The kit online loading and automatic replacement system comprises a reagent disc mechanism, a carrying mechanism, a clamping mechanism and an automatic opening and closing window mechanism; the reagent disc mechanism comprises a reagent disc cover, an outer ring turntable, an inner ring turntable and a reagent pot, and the reagent disc cover is provided with an outer ring loading port, an inner ring loading port and an automatic replacement port. The inner ring turntable and the outer ring turntable are matched with each other, the reagent kits on the inner ring turntable and the outer ring turntable are automatically replaced by the clamping mechanism driven by the carrying mechanism, the reagent kits on the inner ring turntable can be manually replaced through the inner ring loading port, the reagent kits are automatically loaded and replaced online without stopping, the operation efficiency of the instrument is improved, and manpower is saved; meanwhile, the reagent kits to be loaded are refrigerated in the machine, in addition, the automatic opening and closing window mechanism and the carrying mechanism are both arranged on the reagent disc cover, the overall occupied space is reduced, and the overall integration is improved.

Description

Technical Field

[0001] This invention relates to the field of analyzer technology, and in particular to a system and method for online loading and automatic replacement of reagent kits. Background Technology

[0002] To meet the testing needs of different types of samples, fully automated analyzers currently require low-temperature storage of various types of reagents in the reagent tray mechanism to improve instrument efficiency. During use, reagents are drawn from the reagent kit in the reagent tray mechanism and mixed with the sample for reaction.

[0003] Existing fully automated blood analyzers all have a reagent compartment and a turntable inside the reagent compartment in their reagent tray mechanism. When the machine is stopped, the reagent kits are loaded into the loading area of ​​the turntable, and the turntable rotates to transport the reagent kits to the reagent suction port of the reagent compartment for reagent aspiration.

[0004] However, in the existing reagent tray system, emergency testing requires stopping the machine to add reagents, and the machine needs to be stopped to replace reagents when some reagents are used up. This affects the efficiency of the instrument and increases the workload for customers due to the need for manual monitoring of the instrument's operation. At the same time, when replacing reagents, because the performance of the reagents requires storage in a low-temperature environment, the reagents to be used cannot be left in a room temperature environment for a long time. Therefore, the reagents should not be placed in the loading area in advance. When the reagents to be used up are about to run out, it is necessary to manually go back and forth between the refrigerator and the instrument to replace the reagents. This results in the need for manual monitoring and frequent operation during the operation of the instrument, which wastes manpower. Summary of the Invention

[0005] The purpose of this invention is to provide an online loading and automatic replacement system and method for reagent kits, so as to solve the technical problems in the prior art where reagent kits to be loaded cannot be placed in the loading area in advance and cannot be automatically replaced online.

[0006] The present invention provides an online loading and automatic replacement system for reagent kits, comprising: a reagent tray mechanism, a transport mechanism, a clamping mechanism, and an automatic opening and closing window mechanism;

[0007] The reagent tray mechanism includes a reagent tray cover, an outer ring turntable, an inner ring turntable, and a reagent pot for low-temperature storage of reagent kits. The reagent tray cover is placed on the reagent pot, and the outer ring turntable and the inner ring turntable are both located inside the reagent pot and can rotate relative to each other along the same axis.

[0008] The reagent tray cover has an outer ring loading port, an inner ring loading port, an automatic replacement port, and a reagent suction port. The outer ring loading port and the reagent suction port correspond to the outer ring turntable, the inner ring loading port corresponds to the inner ring turntable, and the automatic replacement port corresponds to both the inner ring turntable and the outer ring turntable. An outer ring cover is provided at the outer ring loading port, and an inner ring cover is provided at the inner ring loading port. An automatic opening and closing window mechanism is provided on the reagent tray cover and is used to close or open the automatic replacement port.

[0009] The outer turntable is provided with a plurality of first reagent positions for loading the reagent kit along the circumferential direction, and the inner turntable is provided with a plurality of second reagent positions for loading the reagent kit along the circumferential direction;

[0010] The clamping mechanism is used to clamp the reagent kit, and the transport mechanism is disposed on the reagent tray cover and is used to drive the clamping mechanism to move between the first reagent position and the second reagent position.

[0011] As a further technical solution, the reagent tray mechanism also includes a base plate, an inner ring drive device, and an outer ring drive device;

[0012] The reagent pot has a bottom wall, which is fixedly connected to the bottom plate and has a gap between it and the bottom plate;

[0013] Both the inner ring drive device and the outer ring drive device are mounted on the base plate and are located at the interval. The bottom wall has a through hole. The inner ring drive device passes through the through hole to drive the inner ring turntable to rotate, and the outer ring drive device passes through the through hole to drive the outer ring turntable to rotate.

[0014] As a further technical solution, the inner ring drive device includes a main shaft, an inner ring bushing, an inner ring bearing, an inner ring connecting flange, an inner ring motor, an inner ring synchronous pulley, and an inner ring transmission belt;

[0015] One end of the main shaft is fixedly connected to the base plate, and the other end passes through the through hole. The inner ring bushing is rotatably connected to the main shaft through the inner ring bearing. The inner ring turntable is connected to the inner ring bushing through the inner ring connecting flange.

[0016] The inner ring motor is fixedly connected to the base plate, the inner ring synchronous pulley is fixedly connected to the inner ring bushing, and the output end of the inner ring motor is connected to the inner ring synchronous pulley through the inner ring transmission belt.

[0017] As a further technical solution, the outer ring drive device includes an outer ring bushing, an outer ring bearing, an outer ring connecting flange, an outer ring motor, an outer ring synchronous pulley, an outer ring transmission belt, and an outer ring reduction gear;

[0018] The outer ring bushing is rotatably connected to the inner ring bushing via the outer ring bearing, and the outer ring turntable is connected to the outer ring bushing via the outer ring connecting flange;

[0019] The outer ring motor is fixedly connected to the base plate, the outer ring synchronous pulley is fixedly connected to the outer ring bushing, the output end of the outer ring motor is driven by the outer ring reduction gear, and the outer ring reduction gear is driven by the outer ring transmission belt and the outer ring synchronous pulley.

[0020] As a further technical solution, the reagent tray mechanism also includes an inner ring code disk, an inner ring zero-position optocoupler, an inner ring code tooth optocoupler, an outer ring code disk, an outer ring zero-position optocoupler, and an outer ring code tooth optocoupler;

[0021] The inner ring connecting flange is connected to the upper end of the inner ring bushing, the inner ring code disk is connected to the lower end of the inner ring bushing, and the inner ring zero position optocoupler and the inner ring code tooth optocoupler are both connected to the base plate and cooperate with the inner ring code disk.

[0022] The outer ring connecting flange is connected to the upper end of the outer ring bushing, the outer ring code disk is connected to the lower end of the outer ring bushing, and the outer ring zero-position optocoupler and the outer ring code tooth optocoupler are both connected to the base plate and cooperate with the outer ring code disk.

[0023] As a further technical solution, it also includes an outer RFID reader and an inner RFID reader. The outer RFID reader is disposed inside the reagent pot and is used to read the RFID information of the reagent kit at the first reagent position. The inner RFID reader is disposed on the reagent tray cover and is used to read the RFID information of the reagent kit at the second reagent position.

[0024] As a further technical solution, the automatic opening and closing window mechanism includes a window cover, an auxiliary guide rail, a first motor, a crank, a connecting rod, a linear guide rail, a limit baffle, and a limit optocoupler;

[0025] The auxiliary guide rail and the linear guide rail are arranged opposite to each other and are both fixed on the reagent tray cover. The first motor is fixed to the reagent tray cover and connected to the crank. One end of the connecting rod is hinged to the window cover and the other end is hinged to the crank. The limiting baffle is arranged on the crank. The limiting optocoupler is arranged on the reagent tray cover and cooperates with the limiting baffle.

[0026] As a further technical solution, the clamping mechanism includes a drive device, a front gripper, a rear gripper, a cam, a roller, and a return spring;

[0027] The front gripper and the rear gripper are arranged opposite to each other, and both the front gripper and the rear gripper are provided with rollers. The cam is disposed between the two rollers. The driving device is used to drive the cam to rotate. The cam drives the two rollers to move the front gripper and the rear gripper away from each other by rotating. One end of the return spring is connected to the front gripper and the other end is connected to the rear gripper. The return spring is used to drive the front gripper and the rear gripper to move closer to each other.

[0028] As a further technical solution, the reagent kit is provided with a first positioning part, and both the front gripper and the rear gripper are provided with a second positioning part that cooperates with the first positioning part for positioning.

[0029] As a further technical solution, the conveying mechanism includes an X-axis conveying device and a Z-axis conveying device;

[0030] The X-axis transport device is connected to the reagent tray cover via a support member, the Z-axis transport device is connected to the X-axis transport device, and the clamping mechanism is connected to the Z-axis transport device.

[0031] As a further technical solution, the conveying mechanism also includes an X-axis positioning buffer device and an X-axis positioning detection device disposed on the X-axis conveying device, and a Z-axis positioning buffer device and a Z-axis positioning detection device disposed on the Z-axis conveying device.

[0032] As a further technical solution, the reagent tray mechanism also includes a mixing device disposed within the reagent pot, the mixing device being used to mix the reagent kit.

[0033] As a further technical solution, the reagent tray mechanism also includes a retaining ring disposed on the inner side wall of the reagent pot and used to cooperate with the reagent kit, the retaining ring having a notch corresponding to the automatic replacement port.

[0034] As a further technical solution, the reagent kit has a spring sheet on one side and a snap fastener on the other side. The first reagent position and the second reagent position are both slots, and the slots have opposing first and second sidewalls. The first sidewall is used to engage with the spring sheet, and the second sidewall is used to engage with the snap fastener.

[0035] This invention provides a method for online loading and automatic replacement of reagent kits, using the aforementioned online loading and automatic replacement system, comprising the following steps:

[0036] S1, the reagent kit to be aspirated is loaded into the first reagent position through the outer ring loading port, and the reagent kit to be loaded into the second reagent position through the inner ring loading port, and at least one second reagent position is empty;

[0037] S2, Read the RFID information of the reagent kit on the first reagent position, and read the RFID information of the reagent kit on the second reagent position;

[0038] S3 automatically replaces the kit that has been emptied in the first reagent position with the kit with the same detection item in the second reagent position.

[0039] As a further technical solution, the step S2 of reading the RFID information of the reagent kit on the second reagent bit includes the following steps:

[0040] S211, Open the automatic switching port;

[0041] S212, the inner rotating disk rotates the reagent kit to be read to the automatic replacement port;

[0042] S213, the clamping mechanism picks up the reagent kit to be read and transports it to the inner RFID reader via the conveying mechanism to read the RFID information and match it with the original second reagent position;

[0043] S214, after reading, return to the original second reagent slot;

[0044] S215, repeat S212 to S214 to complete the RFID information reading of all reagent kits.

[0045] As a further technical solution, step S2, reading the RFID information of the reagent kit on the first reagent bit, includes the following steps:

[0046] S221, the outer turntable moves the reagent kit to be read to the outer RFID reader;

[0047] S222, the outer ring RFID reader reads the RFID information of the reagent kit to be read and matches it with the first reagent bit;

[0048] S223, repeat S221~S222 to complete the RFID information reading of all reagent kits.

[0049] As a further technical solution, step S3 includes the following steps:

[0050] S31, open the automatic switching port;

[0051] S32, the inner turntable moves the empty second reagent position to the automatic replacement port. After the reagent kit in the first reagent position is completely aspirated or after mixing is completed, the outer turntable moves the empty reagent kit in the first reagent position to the automatic replacement port.

[0052] S33, the clamping mechanism picks up the empty reagent kit on the first reagent position and transfers it to the empty second reagent position through the transport mechanism;

[0053] S34, the conveying mechanism lifts the clamping mechanism, and when the outer turntable receives a reagent aspiration request from the controller, the outer turntable moves the designated reagent kit to the reagent aspiration port, or when the outer turntable receives a mixing request from the controller, the outer turntable rotates to mix the reagent.

[0054] S35, the inner turntable moves the reagent kit with the same test item on the second reagent position to the automatic replacement port, and when the outer turntable receives a reagent aspiration request from the controller, after the reagent kit on the first reagent position has been aspirated, or when the outer turntable receives a mixing request from the controller, after the mixing is completed, the outer turntable moves the empty first reagent position to the automatic replacement port.

[0055] S36, The clamping mechanism picks up the reagent kit on the second reagent position and transfers it to the empty first reagent position via the transport mechanism;

[0056] S37, repeat S32~S36 to complete the replacement of the reagent kit that has been aspirated from the first reagent position with the reagent kit waiting to be loaded into the second reagent position;

[0057] S38, the conveying mechanism lifts the clamping mechanism and closes the automatic replacement port.

[0058] Compared with the prior art, the technical advantages of the online loading and automatic replacement system and method for reagent kits provided by the present invention are as follows:

[0059] The present invention provides an online loading and automatic replacement system for reagent kits, comprising: a reagent tray mechanism, a transport mechanism, a clamping mechanism, and an automatic opening and closing window mechanism; the reagent tray mechanism includes a reagent tray cover, an outer ring turntable, an inner ring turntable, and a reagent pot for low-temperature storage of reagent kits, the reagent tray cover being disposed on the reagent pot, and the outer ring turntable and the inner ring turntable being disposed inside the reagent pot and capable of rotating relative to each other along the same axis; the reagent tray cover has an outer ring loading port, an inner ring loading port, an automatic replacement port, and a reagent suction port, the outer ring loading port and the reagent suction port corresponding to the outer ring turntable, and the inner ring loading port corresponding to the inner ring turntable. The reagent tray covers the inner and outer rings, with corresponding automatic replacement ports. An outer ring cover is provided at the outer loading port, and an inner ring cover is provided at the inner loading port. An automatic opening and closing window mechanism is located on the reagent tray cover and is used to close or open the automatic replacement port. The outer ring ring has multiple first reagent positions for loading reagent kits along its circumference, and the inner ring ring has multiple second reagent positions for loading reagent kits along its circumference. A clamping mechanism is used to hold and place reagent kits, and a transport mechanism is located on the reagent tray cover and is used to drive the clamping mechanism to move between the first and second reagent positions.

[0060] In operation, the outer turntable rotates, loading reagent kits to be aspirated into the first reagent position through the outer loading port. The inner turntable rotates, loading reagent kits to be loaded into the second reagent position through the inner loading port. At least one second reagent position is empty. When a reagent kit in the first reagent position is emptied and needs to be replaced, the automatic opening and closing window mechanism opens the automatic replacement port. The outer turntable moves the emptied reagent kit in the first reagent position to the automatic replacement port, and the inner turntable moves the empty second reagent position to the automatic replacement port. The conveying mechanism drives the clamping mechanism to move to the first reagent position corresponding to the automatic replacement port. At the designated location, the clamping mechanism picks up the empty reagent kit and moves it to the corresponding automatic replacement port and the empty second reagent position via the transport mechanism. After loading the empty reagent kit into the empty second reagent position, the inner turntable moves the reagent kits with the same test items to the automatic replacement port. The transport mechanism then drives the clamping mechanism to transport and load the reagent kits with the same test items to the empty first reagent position, completing the automatic replacement of the reagent kits to be used with the empty reagent kits. This achieves online automatic loading and replacement of reagent kits without stopping the machine, improving the instrument's operating efficiency and saving manpower.

[0061] Meanwhile, since the outer and inner turntables can rotate independently, when the outer turntable is working, the reagent kits on the second reagent position can be manually replaced through the inner loading port. This allows for online loading and replacement of reagent kits on the second reagent position without stopping the instrument, improving instrument operating efficiency and reducing user workload. Furthermore, the reagent kits to be aspirated and the reagent kits to be loaded can be stored at low temperatures in the reagent pot at the same time, achieving on-site refrigeration of the reagent kits to be loaded, further reducing user workload and improving the user experience.

[0062] In addition, since the automatic window opening and closing mechanism and the conveying mechanism are both located on the reagent tray cover, the overall space occupied is reduced and the overall integration is improved.

[0063] The online loading and automatic replacement method for reagent kits provided by this invention uses the above-mentioned online loading and automatic replacement system for reagent kits. Therefore, the technical advantages and effects achieved by this method include those achieved by the above-mentioned online loading and automatic replacement system for reagent kits, which will not be elaborated here.

[0064] Other features and advantages of the present invention will be described in detail in the following detailed description section. Attached Figure Description

[0065] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0066] Figure 1 This is a schematic diagram of the online loading and automatic replacement system for reagent kits provided in an embodiment of the present invention;

[0067] Figure 2 This is a schematic diagram of the reagent tray mechanism provided in an embodiment of the present invention;

[0068] Figure 3 This is a schematic diagram of the reagent tray mechanism when the reagent tray cover is opened, provided in an embodiment of the present invention.

[0069] Figure 4 This is a schematic diagram of the reagent kit structure provided in an embodiment of the present invention;

[0070] Figure 5 A side view of the reagent tray mechanism provided in an embodiment of the present invention;

[0071] Figure 6 A cross-sectional view of the reagent tray mechanism provided in an embodiment of the present invention;

[0072] Figure 7 Provided for embodiments of the present invention Figure 6 Enlarged view of point A in the middle;

[0073] Figure 8 Provided for embodiments of the present invention Figure 6 Enlarged view at point B in the middle;

[0074] Figure 9 This is a schematic diagram of the structure at the retaining ring provided in an embodiment of the present invention;

[0075] Figure 10 This is a schematic diagram of the inner and outer ring turntable structures of the reagent tray mechanism provided in an embodiment of the present invention;

[0076] Figure 11 Exploded views of the inner ring drive device and the outer ring drive device provided in the embodiments of the present invention;

[0077] Figure 12 This is a schematic diagram of one side of the clamping mechanism provided in an embodiment of the present invention;

[0078] Figure 13 This is a schematic diagram of the structure of the other side of the clamping mechanism provided in an embodiment of the present invention;

[0079] Figure 14 This is a partial exploded view of the clamping mechanism provided in an embodiment of the present invention;

[0080] Figure 15 This is a schematic diagram of the clamping mechanism transmission provided in an embodiment of the present invention;

[0081] Figure 16A schematic diagram comparing the positions of the cam and roller in the three states of the clamping mechanism provided in the embodiments of the present invention: open, clamped, and grasping empty.

[0082] Figure 17 A schematic diagram comparing the positions of the front and rear jaws of the clamping mechanism provided in this embodiment of the invention in three states: open, clamped, and grasping empty.

[0083] Figure 18 This is a schematic diagram of the handling mechanism structure provided in an embodiment of the present invention;

[0084] Figure 19 An exploded view of the Z-axis conveying device provided in an embodiment of the present invention;

[0085] Figure 20 A schematic diagram of the Z-axis positioning buffer device and the Z-axis positioning detection device provided in an embodiment of the present invention;

[0086] Figure 21 A position comparison diagram of the Z-axis conveying device in the embodiments of the present invention, showing the three states of lifting, grasping, and positioning buffer.

[0087] Figure 22 This is a comparison diagram of the Z-axis driving plate and the Z-axis limiting pin in a tightly attached state and a disengaged state, provided in an embodiment of the present invention.

[0088] Figure 23 An exploded view of the X-axis conveying device provided in an embodiment of the present invention;

[0089] Figure 24 A comparison diagram of the snap-fit ​​and detachment states of the reagent kit provided in this embodiment of the invention;

[0090] Figure 25 A comparison diagram of the engagement state between the spring and the outer rotating disk during the removal process of the reagent kit provided in this embodiment of the invention;

[0091] Figure 26 A comparison diagram of two states during the positioning buffer state process of the X-direction conveying device provided in an embodiment of the present invention;

[0092] Figure 27 This is a schematic diagram of the closed state of the automatic opening and closing window mechanism provided in an embodiment of the present invention;

[0093] Figure 28 This is a schematic diagram of the open state of the automatic opening and closing window mechanism provided in an embodiment of the present invention;

[0094] Figure 29 This is a schematic diagram of the clamping mechanism provided in an embodiment of the present invention clamping the reagent kit on the inner circle turntable to the inner circle RFID reader;

[0095] Figure 30The flowchart illustrates the automatic reagent kit replacement process provided in this embodiment of the invention.

[0096] Icons: 1-Reagent tray mechanism; 2-Transfer mechanism; 3-Clamping mechanism; 4-Automatic opening and closing window mechanism; 5-Reagent tray cover; 6-Outer ring turntable; 7-Inner ring turntable; 8-Reagent pot; 9-Outer ring loading port; 10-Inner ring loading port; 11-Automatic changing port; 12-Reagent suction port; 13-Outer ring cover; 14-Inner ring cover; 15-First reagent position; 16-Second reagent position; 17-Base plate; 18-Bottom wall; 19-Main shaft; 20-Inner ring bushing; 21-Inner ring bearing; 22-Inner ring connecting flange; 23-Inner ring motor; 24-Inner ring synchronous pulley; 25-Inner ring transmission belt; 26-Outer ring bushing; 27-Outer ring bearing; 28-Outer ring connecting flange; 29-Outer ring motor; 30-Outer ring synchronous pulley; 31-Outer ring... 32-Outer ring drive belt; 33-Inner ring encoder; 34-Lower end face; 35-Outer ring flange nut; 36-Outer ring encoder; 37-Outer ring zero-position optocoupler; 38-Outer ring code tooth optocoupler; 39-Outer ring RFID reader; 40-Inner ring RFID reader; 41-Window cover; 42-Auxiliary guide rail; 43-First motor; 44-Crank; 45-Connecting rod; 46-Linear guide rail; 47-Limit stop plate; 48-Limit optocoupler; 49-Front gripper; 50-Rear gripper; 51-Cam; 52-Return spring; 53-X-direction conveying device; 54-Z-direction conveying device; 55-Retaining ring; 56-Notch; 57-Spring; 58-Snap fastener; 59-Side wall; 60-Bottom insulation layer; 61-Outer ring insulation layer ; 62-Inner ring insulation layer; 63-Motor bracket; 64-Second motor; 65-Motor mounting plate; 66-Front connecting frame; 67-Rear connecting frame; 68-Clamping guide rail; 69-Grip detection optocoupler; 70-Grip detection baffle; 71-Grip zero-position optocoupler; 72-Grip zero-position baffle; 73-Clamping base plate; 74-Positioning spring; 75-Pressing box frame; 76-Roller; 77-Roller shaft; 78-Reagent kit; 79-Reagent bottle bracket; 80-First reagent bottle; 81-Second reagent bottle; 82-Magnetic bead bottle; 83-Mixing gear support column; 84-X-direction belt pressure plate; 85-Positioning clamping hole; 86-Clamping pin; 87-Support column; 88-Z-direction motor assembly; 89-Z-direction base plate; 90-Z-direction synchronous belt; 91- Z-axis driven wheel assembly; 92-Z-axis drive plate; 93-Z-axis linear guide; 94-Z-axis slider mounting plate; 95-Z-axis loading linear track; 96-Z-axis belt pressure plate; 97-Z-axis zero-position optocoupler; 98-Z-axis zero-position baffle; 99-Z-axis position detection baffle; 100-Z-axis position detection optocoupler; 101-Z-axis limit pin; 102-Z-axis loading spring; 103-X-axis motor assembly; 104-X-axis base plate; 105-X-axis synchronous belt; 106-X-axis driven wheel assembly; 107-X-axis drive plate; 108-X-axis linear guide; 109-X-axis slider mounting plate; 110-X-axis loading linear track; 111-X-axis zero-position optocoupler; 112-X-axis zero-position baffle; 113-X-axis position detection optocoupler;114 - X-direction limiting pin; 115 - X-direction loading spring; 116 - Sector-shaped mixing gear. Detailed Implementation

[0097] The technical solution of the present invention will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0098] In the description of this invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0099] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0100] Furthermore, the technical solutions of the various embodiments can be combined with each other, but only if they are feasible for those skilled in the art. If the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such combination of technical solutions does not exist and is not within the scope of protection claimed by this invention.

[0101] The present invention will now be described in further detail with reference to specific embodiments and accompanying drawings.

[0102] The specific structure is as follows: Figures 1 to 30 As shown.

[0103] This embodiment provides an online loading and automatic replacement system for reagent kits, including: a reagent tray mechanism 1, a conveying mechanism 2, a clamping mechanism 3, and an automatic opening and closing window mechanism 4; the reagent tray mechanism 1 includes a reagent tray cover 5, an outer ring turntable 6, an inner ring turntable 7, and a reagent pot 8 for low-temperature storage of reagent kits 78. The reagent tray cover 5 covers the reagent pot 8, and the outer ring turntable 6 and the inner ring turntable 7 are both disposed inside the reagent pot 8 and can rotate relative to each other along the same axis; the reagent tray cover 5 has an outer ring loading port 9, an inner ring loading port 10, an automatic replacement port 11, and a reagent suction port 12. The outer ring loading port 9 and the reagent suction port 12 correspond to the outer ring turntable 6, and the inner ring loading port 10 corresponds to the inner ring turntable 6. Corresponding to tray 7, the automatic replacement port 11 corresponds to both the inner ring turntable 7 and the outer ring turntable 6. An outer ring cover 13 is provided at the outer ring loading port 9, and an inner ring cover 14 is provided at the inner ring loading port 10. An automatic opening and closing window mechanism 4 is provided on the reagent tray cover 5 and is used to close or open the automatic replacement port 11. The outer ring turntable 6 is provided with multiple first reagent positions 15 for loading reagent kits 78 along the circumference, and the inner ring turntable 7 is provided with multiple second reagent positions 16 for loading reagent kits 78 along the circumference. The clamping mechanism 3 is used to clamp and place the reagent kits 78, and the conveying mechanism 2 is provided on the reagent tray cover 5 and is used to drive the clamping mechanism 3 to move between the first reagent positions 15 and the second reagent positions 16.

[0104] In this embodiment, during use, the outer ring turntable 6 rotates, loading the reagent kit 78 to be aspirated into the first reagent position 15 through the outer ring loading port 9. The inner ring turntable 7 rotates, loading the reagent kit 78 to be loaded into the second reagent position 16 through the inner ring loading port 10. At least one second reagent position 16 is empty. When the reagent kit 78 in the first reagent position 15 is emptied and needs to be replaced, the automatic opening and closing window mechanism 4 opens the automatic replacement port 11. The outer ring turntable 6 moves the emptied reagent kit 78 in the first reagent position 15 to the automatic replacement port 11, and the inner ring turntable 7 moves the empty second reagent position 16 to the automatic replacement port 11. The conveying mechanism 2 drives the clamping mechanism 3 to move to the corresponding automatic replacement port 11. At the first reagent position 15, the clamping mechanism 3 picks up the empty reagent kit 78. The transport mechanism 2 drives the clamping mechanism 3 to move to the corresponding automatic replacement port 11 and the empty second reagent position 16. After the empty reagent kit 78 is loaded into the empty second reagent position 16, the inner turntable 7 moves the reagent kit 78 with the same test items to the automatic replacement port 11. The transport mechanism 2 drives the clamping mechanism 3 to transport and load the reagent kit 78 with the same test items onto the empty first reagent position 15. This completes the automatic replacement of the reagent kit 78 to be used with the empty reagent kit 78, realizing online automatic loading and replacement of reagent kit 78 without stopping the machine, improving the operating efficiency of the instrument and saving manpower.

[0105] Meanwhile, since the outer turntable 6 and the inner turntable 7 can rotate independently, when the outer turntable 6 is working, the reagent kit 78 on the second reagent position 16 can be manually replaced through the inner loading port 10. This allows for online loading and replacement of the reagent kit 78 on the second reagent position 16 without stopping the machine, improving instrument operating efficiency and reducing user workload. Furthermore, the reagent kit 78 to be aspirated and the reagent kit 78 to be loaded can be stored at low temperature in the reagent pot 8 at the same time, sharing a set of refrigeration systems to achieve on-machine refrigeration of the reagent kit 78 to be loaded, further reducing user workload and improving user experience.

[0106] In addition, since the automatic opening and closing window mechanism 4 and the conveying mechanism 2 are both located on the reagent tray cover 5, the overall space occupied is reduced and the overall integration is improved.

[0107] In the optional technical solution of this embodiment, the reagent tray mechanism 1 further includes a base plate 17, an inner ring drive device, and an outer ring drive device; the reagent pot 8 has a bottom wall 18, which is fixedly connected to the base plate 17 and is spaced apart from the base plate 17; the inner ring drive device and the outer ring drive device are both disposed on the base plate 17 and are both located at the interval; the bottom wall 18 has a through hole, through which the inner ring drive device passes to drive the inner ring turntable 7 to rotate, and through which the outer ring drive device passes to drive the outer ring turntable 6 to rotate.

[0108] In this embodiment, the reagent pot 8 is equipped with a refrigeration system to enable the reagent pot 8 to preserve the reagent kit 78 at low temperatures. A bottom insulation layer 60 is provided on the outside of the bottom wall 18 of the reagent pot 8, an outer ring insulation layer 61 is provided on the outside of the side wall 59 of the reagent pot 8, and an inner ring insulation layer 62 is provided at the through hole. The bottom insulation layer 60, the outer ring insulation layer 61, and the inner ring insulation layer 62 are all used to reduce heat exchange between the inside and outside of the reagent pot 8 and ensure that the inside of the reagent pot 8 is in a low-temperature state. The bottom insulation layer 60, the outer ring insulation layer 61, and the inner ring insulation layer 62 are all made of insulation material. Preferably, the bottom insulation layer 60, the outer ring insulation layer 61, and the inner ring insulation layer 62 are all insulation cotton, which has low cost and good insulation effect.

[0109] In this embodiment, the bottom wall 18 of the reagent pot 8 is fixedly connected to the base plate 17 by a support member, and the support member supports the reagent pot 8 and forms a gap between it and the base plate 17. The inner ring drive device and the outer ring drive device are both set at the gap, which improves the space utilization and makes it convenient to independently control the operation of the inner ring turntable 7 and the outer ring turntable 6 through the control module to achieve automated operation.

[0110] In the optional technical solution of this embodiment, the inner ring drive device includes a main shaft 19, an inner ring bushing 20, an inner ring bearing 21, an inner ring connecting flange 22, an inner ring motor 23, an inner ring synchronous pulley 24, and an inner ring transmission belt 25; one end of the main shaft 19 is fixedly connected to the base plate 17, and the other end passes through the through hole; the inner ring bushing 20 is rotatably connected to the main shaft 19 through the inner ring bearing 21; the inner ring turntable 7 is connected to the inner ring bushing 20 through the inner ring connecting flange 22; the inner ring motor 23 is fixedly connected to the base plate 17; the inner ring synchronous pulley 24 is fixedly connected to the inner ring bushing 20; and the output end of the inner ring motor 23 is connected to the inner ring synchronous pulley 24 through the inner ring transmission belt 25.

[0111] In this embodiment, the inner ring drive device uses the base plate 17 as a carrier, and the main shaft 19 is fixedly connected to the base plate 17. The inner ring bushing 20 is connected and supported to the main shaft 19 through the inner ring bearing 21. The lower end of the inner ring bushing 20 is fixedly connected to the inner ring synchronous pulley 24. The inner ring motor 23 drives the inner ring synchronous pulley 24 to rotate around the main shaft 19 through the inner ring transmission belt 25. The inner ring bushing 20 moves in a circular motion together with the inner ring synchronous pulley 24, and then drives the inner ring turntable 7 to rotate through the inner ring connecting flange 22. The overall structure is simple, and the transmission effect is stable and reliable.

[0112] In the optional technical solution of this embodiment, the outer ring drive device includes an outer ring bushing 26, an outer ring bearing 27, an outer ring connecting flange 28, an outer ring motor 29, an outer ring synchronous pulley 30, an outer ring transmission belt 31, and an outer ring reduction gear 32. The outer ring bushing 26 is rotatably connected to the inner ring bushing 20 through the outer ring bearing 27, and the outer ring turntable 6 is connected to the outer ring bushing 26 through the outer ring connecting flange 28. The outer ring motor 29 is fixedly connected to the base plate 17, the outer ring synchronous pulley 30 is fixedly connected to the outer ring bushing 26, and the output end of the outer ring motor 29 is driven by the outer ring reduction gear 32. The outer ring reduction gear 32 is driven by the outer ring transmission belt 31 and the outer ring synchronous pulley 30.

[0113] In this embodiment, the outer ring drive device uses the inner ring bushing 20 as a carrier. The outer ring bushing 26 and the inner ring bushing 20 are connected and supported by bearings. The outer ring connecting flange 28 and the outer ring bushing 26 are connected by the outer ring flange nut 35. The lower end of the outer ring bushing 26 is fixedly connected to the outer ring synchronous pulley 30. The outer ring motor 29 is reduced in one stage by the outer ring reduction gear 32 and then driven by the outer ring transmission belt 31 to rotate the outer ring synchronous pulley 30 around the main shaft 19. The outer ring bushing 26 moves in a circular motion with the outer ring synchronous pulley 30, and then drives the outer ring turntable 6 to rotate through the outer ring connecting flange 28. The overall structure is simple, the transmission effect is stable and reliable, and both the outer ring drive device and the inner ring drive device are integrated with the main shaft 19, reducing the space occupied.

[0114] In the optional technical solution of this embodiment, the reagent tray mechanism 1 further includes an inner ring code disk 33, an inner ring zero-position optocoupler, an inner ring code tooth optocoupler, an outer ring code disk 36, an outer ring zero-position optocoupler 37, and an outer ring code tooth optocoupler 38; the inner ring connecting flange 22 is connected to the upper end of the inner ring bushing 20, the inner ring code disk 33 is connected to the lower end of the inner ring bushing 20, and the inner ring zero-position optocoupler and the inner ring code tooth optocoupler are both connected to the base plate 17 and cooperate with the inner ring code disk 33; the outer ring connecting flange 28 is connected to the upper end of the outer ring bushing 26, the outer ring code disk 36 is connected to the lower end of the outer ring bushing 26, and the outer ring zero-position optocoupler 37 and the outer ring code tooth optocoupler 38 are both connected to the base plate 17 and cooperate with the outer ring code disk 36.

[0115] In this embodiment, both the inner ring connecting flange 22 and the outer ring connecting flange 28 are made of non-thermal conductive materials and are respectively located on the upper end face of the inner ring bushing 20 and the upper end face of the outer ring bushing 26, effectively reducing heat transfer to the outer ring turntable 6 and the inner ring turntable 7. Meanwhile, an inner ring encoder 33 is fixedly connected to the lower end of the inner ring bushing 20, and is matched with an inner ring zero-position optocoupler and an inner ring code tooth optocoupler. The inner ring zero-position optocoupler and the inner ring code tooth optocoupler are respectively fixed to the base plate 17 by a fixing bracket. The inner ring zero-position optocoupler and the inner ring encoder 33 cooperate to position the initial position of the inner ring turntable 7, that is, to position the first second reagent position 16. The inner ring code tooth optocoupler and the inner ring encoder 33 cooperate to ensure the movement accuracy of the inner ring turntable 7, ensuring that the second reagent position 16 can accurately correspond to the automatic changing port 11. An outer ring encoder 36 is fixedly connected to the lower end of the outer ring bushing 26, and is matched with an outer ring zero-position optocoupler 37 and an outer ring code tooth optocoupler 38. The outer ring zero-position optocoupler 37 and the outer ring code tooth optocoupler 38 are respectively fixed on the base plate 17 by a fixing bracket. The outer ring zero-position optocoupler 37 and the outer ring encoder 36 cooperate to position the initial position of the outer ring turntable 6, that is, to position the first reagent position 15. The outer ring code tooth optocoupler 38 and the outer ring encoder 36 cooperate to ensure the movement accuracy of the outer ring turntable 6, and ensure that the first reagent position 15 can accurately correspond to the automatic changing port 11.

[0116] In the optional technical solution of this embodiment, an outer ring RFID reader 39 and an inner ring RFID reader 40 are also included. The outer ring RFID reader 39 is disposed inside the reagent pot 8 and is used to read the RFID information of the reagent kit 78 on the first reagent position 15. The inner ring RFID reader 40 is disposed on the reagent tray cover 5 and is used to read the RFID information of the reagent kit 78 on the second reagent position 16.

[0117] In this embodiment, both the outer RFID reader 39 and the inner RFID reader 40 are components that read the RFID code on the end face of the reagent kit 78. The outer RFID reader 39 reads the RFID information of the reagent kit 78 to be absorbed on the first reagent position 15 and matches it with its corresponding first reagent position 15. The inner RFID reader 40 reads the RFID information of the reagent kit 78 to be installed on the second reagent position 16 and matches it with its corresponding second reagent position 16. This ensures the accuracy of replacing the reagent kit 78 on the first reagent position 15 with the reagent kit 78 on the second reagent position 16, while also ensuring the accuracy of the overall operation.

[0118] In the optional technical solution of this embodiment, the automatic opening and closing window mechanism 4 includes an auxiliary guide rail 42, a first motor 43, a crank 44, a connecting rod 45, and a linear guide rail 46. The auxiliary guide rail 42 and the linear guide rail 46 are arranged opposite to each other and are both fixed on the reagent tray cover 5. The auxiliary guide rail 42 is located at the end of the automatic changing port 11 near the outer ring turntable 6, and the linear guide rail 46 is located at the end of the automatic changing port 11 near the inner ring turntable 7. The outer ring RFID reader 39 is fixed on the reagent tray cover 5 and is located at the auxiliary guide rail 42. Motor 43 is fixed to reagent tray cover 5 via motor bracket 63. The output end of the first motor 43 is connected to crank 44. One end of connecting rod 45 is hinged to window cover 41, and the other end is hinged to one end of crank 44. A limit stop plate 47 is provided at the other end of crank 44. A limit optocoupler 48 is provided on reagent tray cover 5. The limit stop plate 47 and the limit optocoupler 48 cooperate to limit the rotation angle of the first motor 43, thereby enabling the first motor 43 to accurately open or close the automatic replacement port 11 via crank 44 and connecting rod 45. The first drive device has a simple and compact overall structure, occupies little space, and provides stable and precise drive. At the same time, the hinged ends of connecting rod 45 can effectively prevent jamming.

[0119] When there is a need to replace reagent kit 78, crank 44 rotates with the output end of the first motor 43, driving connecting rod 45 to move, thereby pushing / pulling window cover 41 to reciprocate along linear guide rail 46 and auxiliary guide rail 42. At the same time, when there is no need to replace reagent kit 78, automatic replacement port 11 remains closed, which keeps reagent pot 8 warm.

[0120] In the optional technical solution of this embodiment, the clamping mechanism 3 includes a driving device, a front gripper 49, a rear gripper 50, a cam 51, rollers, and a return spring 52. The front gripper 49 and the rear gripper 50 are arranged opposite to each other, and both the front gripper 49 and the rear gripper 50 are provided with rollers. The cam 51 is arranged between the two rollers. The driving device is used to drive the cam 51 to rotate. The cam 51 drives the two rollers to move the front gripper 49 and the rear gripper 50 away from each other by rotating. One end of the return spring 52 is connected to the front gripper 49, and the other end is connected to the rear gripper 50. The return spring 52 is used to drive the front gripper 49 and the rear gripper 50 to move closer to each other.

[0121] In this embodiment, the cam 51 is connected to the two rollers through a cam pair. The driving device drives the cam 51 to rotate, causing the two rollers to move away from each other, thereby causing the front gripper 49 and the rear gripper 50 to open. The tension of the return spring 52 causes the front gripper 49 and the rear gripper 50 to return to their original position and clamp, thus realizing the function of the front gripper 49 and the rear gripper 50 in clamping and placing the reagent kit 78. The structure is simple, the drive is convenient, and the clamping and placing is stable. At the same time, the cam 51 cooperates with the two rollers to drive, avoiding drive jamming and improving stability.

[0122] Specifically, the drive unit includes a second motor 64, a motor mounting plate 65, a front connecting frame 66, a rear connecting frame 67, a clamping guide rail 68, a gripping void detection optocoupler 69, a gripping void detection baffle 70, a gripper zero-position optocoupler 71, a gripper zero-position baffle 72, a clamping base plate 73, a positioning spring 74, and a pressure box frame 75. The second motor 64 is mounted on the upper side of the clamping base plate 73 via the motor mounting plate 65. The clamping guide rails 68 are mounted on the lower side of the clamping base plate 73, and a pair of clamping guide rails 68 are provided. The front gripper 49 is slidably connected to the pair of clamping guide rails 68 via the front connecting frame 66, and the rear gripper 50 is slidably connected to the rear connecting frame 67 via the rear connecting frame 67. The rollers are connected between a pair of clamping guide rails 68. The rollers include rollers 76 and roller shafts 77. The roller shafts 77 of the two rollers are respectively connected to the front connecting frame 66 and the rear connecting frame 67. The cam 51 is located between the rollers 76 of the two rollers and is connected to the cam 51 of the rollers 76. The zero-position optocoupler 71 of the gripper is set on the clamping base plate 73. The zero-position baffle 72 of the gripper is set on the upper end of the cam 51. The zero-position optocoupler 71 of the gripper and the zero-position baffle 72 of the gripper cooperate with each other to limit the rotation angle of the second motor 64, so that the second motor 64 can accurately drive the front gripper 49 and the rear gripper 50 to clamp and place through the cam 51.

[0123] A gap-grabbing detection optical coupler 69 is mounted on the clamping base plate 73, and a gap-grabbing detection baffle 70 is mounted on the rear connecting frame 67. When the front gripper 49 and the rear gripper 50 are in the open state, the distance between the gap-grabbing detection optical coupler 69 and the front end of the gap-grabbing detection baffle 70 is 'a', and the gap-grabbing detection baffle 70 does not obstruct the gap-grabbing detection optical coupler 69. When the front gripper 49 and the rear gripper 50 are in the clamping state, the distance between the gap-grabbing detection optical coupler 69 and the front end of the gap-grabbing detection baffle 70 is 'b', and the gap-grabbing detection baffle 70 does not obstruct the gap-grabbing detection optical coupler 69. When the front gripper 49 and the rear gripper 50 are in a gap-grabbing state, the distance between the gap-grabbing detection optical coupler 69 and the front end of the gap-grabbing detection baffle 70 is 'c', and the gap-grabbing detection baffle 70 obstructs the gap-grabbing detection optical coupler 69. Through the cooperation of the gap-grabbing detection optical coupler 69 and the gap-grabbing detection baffle 70, the accuracy of the grip is ensured, and gap-grabbing is avoided.

[0124] The two ends of the positioning spring 74 are connected to the clamping base plate 73 and the rear connecting frame 67 respectively through the positioning frame. The positioning spring 74 positions the rear gripper 50 to improve the stability and accuracy of clamping. The pressure box frame 75 is set on the rear gripper 50 and is located between the front gripper 49 and the rear gripper 50. It is used to cooperate in gripping the reagent kit 78 and prevent the reagent kit 78 from tilting when gripping it.

[0125] In the optional technical solution of this embodiment, the reagent kit 78 is provided with a first positioning part, and the front gripper 49 and the rear gripper 50 are both provided with a second positioning part that cooperates with the first positioning part for positioning.

[0126] In this embodiment, the reagent kit 78 includes a reagent bottle holder 79, a first reagent bottle 80, a second reagent bottle 81, and a magnetic bead bottle 82. The first reagent bottle 80 and the second reagent bottle 81 are snapped onto the reagent bottle holder 79, and the magnetic bead bottle 82 is rotatably connected to the reagent bottle holder 79. A spring clip 57 is provided on one side of the reagent bottle holder 79, and a latch 58 is provided on the opposite side. The reagent bottle holder 79 also has a first positioning part. When the front gripper 49 and the rear gripper 50 grip the reagent kit 78, the second positioning part on the front gripper 49 and the rear gripper 50 cooperates with the first positioning part on the reagent bottle holder 79 to ensure the stability of the reagent kit 78 gripping and prevent slippage. It should be noted that the reagent bottle holder 79 is not limited to the first reagent bottle 80 and the second reagent bottle 81; other reagent bottles can also be set on it, meaning the number of reagent bottles can be set according to requirements.

[0127] In this preferred embodiment, the first positioning part is a positioning clamping hole 85 provided on the reagent bottle support 79, and the second positioning part is a clamping pin 86. The structure is simple and the positioning effect is good. Furthermore, multiple positioning clamping holes 85 and clamping pins 86 are provided and correspond one-to-one, which further improves the stability of clamping.

[0128] In the optional technical solution of this embodiment, the conveying mechanism 2 includes an X-axis conveying device 53 and a Z-axis conveying device 54. The X-axis conveying device 53 is connected to the reagent tray cover 5 via a support column 87, and the Z-axis conveying device 54 is connected to the X-axis conveying device 53. The clamping mechanism 3 is connected to the Z-axis conveying device 54. The X-axis is horizontal, and the Z-axis is vertical. That is, the Z-axis conveying mechanism 2 can reciprocate up and down, and the X-axis conveying mechanism 2 can reciprocate radially along the inner ring turntable 7, providing Z-axis and X-axis power for the clamping mechanism 3 to convey the reagent kit 78. The step-by-step conveying by the X-axis conveying device 53 and the Z-axis conveying device 54 ensures the stability and accuracy of the conveying process.

[0129] Specifically, the conveying mechanism 2 also includes a Z-axis positioning buffer device and a Z-axis positioning detection device. The Z-axis conveying device 54 includes a Z-axis motor assembly 88, a Z-axis base plate 89, a Z-axis synchronous belt 90, a Z-axis driven wheel assembly 91, a Z-axis drive plate 92, a Z-axis linear guide rail 93, a Z-axis slider mounting plate 94, a Z-axis loading linear track 95, and a Z-axis pressure plate 96. The Z-axis positioning detection device includes a Z-axis zero-position optocoupler 97, a Z-axis zero-position baffle 98, a Z-axis positioning detection baffle 99, and a Z-axis positioning detection optocoupler 100. The Z-axis positioning buffer device includes a Z-axis limit pin 101 and a Z-axis loading spring 102.

[0130] In this embodiment, the Z-axis motor assembly 88, the Z-axis driven wheel assembly 91, the Z-axis linear guide rail 93, and the Z-axis zero-position optocoupler 97 are all connected to the Z-axis base plate 89. The Z-axis linear guide rail 93 has a slider, and the slider can move linearly along the length direction of the Z-axis linear guide rail 93. The Z-axis slider mounting plate 94 is connected to the slider of the Z-axis linear guide rail 93. The Z-axis loading linear guide rail 46 is mounted on the Z-axis slider mounting plate 94 by screws. The Z-axis zero-position baffle 98 and the Z-axis position detection baffle 99 are both fixed on the Z-axis slider mounting plate 94. The Z-axis loading linear guide rail 46 has a slider, and it can move linearly along the length direction of the Z-axis loading linear guide rail 46. The Z-axis drive plate 92 is mounted on the slider of the Z-axis loading linear guide rail 46 and can move together with the slider. The two ends of the Z-direction synchronous belt 90 are respectively fitted onto the Z-direction motor assembly 88 and the Z-direction driven pulley assembly 91. The Z-direction drive plate 92 is connected to the Z-direction synchronous belt 90 through the Z-direction belt pressure plate 96. The Z-direction motor assembly 88 drives the Z-direction synchronous belt 90 to move, thereby causing the Z-direction drive plate 92 to move in a straight line synchronously.

[0131] There are two Z - direction loading springs 102. One end of the Z - direction loading spring 102 is hung on the Z - direction limit pin 101, and the other end is hung on the lower end of the Z - direction driving plate 92. The Z - direction loading spring 102 pulls the upper end of the Z - direction driving plate 92 along the Z - direction loading linear guide 46 to be attached to the Z - direction limit pin 101. The Z - direction in - place detection optocoupler 100 is fixed on the Z - direction driving plate 92 and moves together with the Z - direction driving plate 92. Since the Z - direction zero - position optocoupler 97 determines the zero - position of the movement of the Z - direction driving plate 92, when the clamping mechanism 3 picks up the reagent kit 78 and places it on the outer - ring turntable 6 or the inner - ring turntable 7, when the Z - direction driving plate 92 moves downward by a length of L from the zero - position, theoretically, the bottom of the reagent kit 78 has contacted the bottom of the first reagent position 15 or the bottom of the second reagent position 16. However, due to the height error of the reagent kit 78, when placing the reagent kit 78, if the Z - direction driving plate 92 moves downward a distance > L, it will cause the Z - direction motor assembly 88 to lose steps; if the Z - direction driving plate 92 moves downward a distance < L, the reagent kit 78 is not placed in place, introducing other faults. In addition, the first reagent position 15 and the second reagent position 16 need to precisely position the reagent kit 78 in the width direction. The gap in the width direction of the reagent kit 78 is very small. When the reagent kit 78 is inserted into the first reagent position 15 or the second reagent position 16, it is required to align with the first reagent position 15 or the second reagent position 16. However, in fact, the alignment error between the reagent kit 78 and the first reagent position 15 or the second reagent position 16 is greater than the fitting gap between the reagent kit 78 and the first reagent position 15 and the second reagent position 16. Therefore, when the reagent kit 78 is inserted, there will be a rigid impact with the sides of the first reagent position 15 and the second reagent position 16, which will also cause the Z - direction motor assembly 88 to lose steps.

[0132] Therefore, in this embodiment, a Z - direction in - place buffer device and a Z - direction in - place detection device are provided. During the process of inserting the reagent kit 78 into the first reagent position 15 and the second reagent position 16, when the Z - direction driving plate 92 moves downward a distance of L, theoretically, at this time, the reagent kit 78 has reached the bottom of the first reagent position 15 or the bottom of the second reagent position 16. However, in order to ensure effective contact with the bottom and then continue to move downward a distance g, when the Z - direction motor assembly 88 continues to drive the Z - direction synchronous belt 90 to carry the Z - direction driving plate 92 to continue moving downward, the Z - direction driving plate 92 gradually detaches from being tightly attached to the Z - direction limit pin 101 until the Z - direction driving plate 92 detaches from and triggers the Z - direction in - place detection optocoupler 100, which is then considered that the reagent kit 78 is in place.

[0133] The conveying mechanism 2 also includes an X-axis positioning buffer device and an X-axis positioning detection device. The X-axis conveying device 53 includes an X-axis motor assembly 103, an X-axis base plate 104, an X-axis synchronous belt 105, an X-axis driven wheel assembly 106, an X-axis drive plate 107, an X-axis linear guide rail 108, an X-axis slider mounting plate 109, and an X-axis loading linear track 110. The X-axis positioning detection device includes an X-axis zero-position optocoupler 111, an X-axis zero-position baffle 112, and an X-axis positioning detection optocoupler 113. The X-axis positioning buffer device includes an X-axis limit pin 114 and an X-axis loading spring 115.

[0134] The X-axis motor assembly 103, the X-axis driven wheel assembly 106, the X-axis linear guide rail 108, and the X-axis zero-position optocoupler 111 are connected to the X-axis base plate 104. The X-axis linear guide rail 108 has a slider, and the slider can move linearly along the length of the X-axis linear guide rail 108. The X-axis slider mounting plate 109 is connected to the slider of the X-axis linear guide rail 108. The X-axis loading linear guide rail 46 is mounted on the X-axis slider mounting plate 109 by screws. The X-axis loading linear guide rail 46 has a slider, and it can move linearly along the length of the X-axis loading linear guide rail 46. The X-axis drive plate 107 is mounted on the slider of the X-axis loading linear guide rail 46 and can move together with the slider. The two ends of the X-direction synchronous belt 105 are respectively fitted onto the X-direction motor assembly 103 and the X-direction driven pulley assembly. The X-direction drive plate 107 is connected to the X-direction synchronous belt through the X-direction belt pressure plate 84. The X-direction motor assembly 103 drives the X-direction synchronous belt 105 to move, thereby causing the X-direction drive plate 107 to move in a straight line synchronously.

[0135] Similar to the Z-axis conveying device 54, two X-axis loading springs 115 are provided. One end of the X-axis loading spring 115 is hung on the X-axis limiting pin 114, and the other end is hung on the end of the X-axis driving plate 107 away from the X-axis limiting pin 114. The X-axis loading spring 115 pulls the end of the X-axis driving plate 107 close to the X-axis limiting pin 114 along the X-axis loading linear guide 46, so that it is attached to the X-axis limiting pin 114. The X-axis positioning detection optocoupler 113 is fixed on the X-axis driving plate 107 and moves together with the X-axis driving plate 107. When the clamping mechanism 3 picks up the reagent kit 78 on the outer ring turntable 6, the distance e from the buckle 58 of the reagent bottle holder 79 extending into the outer ring turntable 6 makes it impossible for the clamping mechanism 3 to remove the reagent kit 78 vertically upwards. Therefore, the X-axis conveying device 53 needs to move one end d in the opposite direction along the buckle 58, and d > e is required. At the same time, the distance d is compressed on the spring 57 of the reagent kit 78, where d = uncompressed distance f - compressed distance f′. In this way, the reagent kit 78 can be effectively removed from the edge of the outer ring turntable 6 before being removed upwards. To avoid rigid impact during the X-axis movement of the reagent kit 78, which could cause the X-axis motor assembly 103 to lose synchronization, and to effectively detect that the movement distance of the reagent kit 78 is greater than d, and to effectively detect that the buckle 58 of the reagent kit 78 has disengaged from the outer ring turntable 6, an X-axis positioning detection optocoupler 11 is connected to the X-axis drive plate 107. 3. The X-axis motor assembly 103 drives the X-axis synchronous belt 105, thereby driving the X-axis drive plate 107 to move. The X-axis drive plate 107 transmits the pulling force to the X-axis limit pin 114 through the X-axis loading spring 115. The X-axis limit pin 114 is fixed on the X-axis slider mounting plate 109, and the X-axis conveying mechanism 2 is fixed to the X-axis slider mounting plate 109 by screws. Therefore, the X-axis drive plate 107 ultimately transmits the power of the X-axis motor assembly 103 to the clamping mechanism 3 through the spring, moving the reagent kit 78 a distance d. When the distance d is moved to the position, the X-axis loading spring 115 continues to overcome the resistance of the spring piece 57 of the reagent kit 78 and generates tensile deformation until the X-axis zero position baffle 112 (X-axis position detection baffle) disengages from the X-axis position detection optocoupler 113 (non-triggered state). At this time, the trigger distance K of the X-axis zero position baffle 112 is greater than d, and the clamping mechanism 3 can reliably remove the reagent kit 78.

[0136] In the optional technical solution of this embodiment, the reagent tray mechanism 1 further includes a mixing device disposed in the reagent pot 8, which is used to mix the reagent kit 78.

[0137] In this embodiment, the mixing device includes multiple sector-shaped mixing gears 116, preferably four, which are evenly fixed to the inner bottom surface of the reagent pot 8 by screws through the mixing gear support column 83. When the reagent kit 78 of the outer ring turntable 6 rotates around the axis of the reagent tray mechanism 1, it also rotates around the axis of the sector-shaped mixing gear 116. Since the magnetic bead bottle 82 and the sector-shaped mixing gear 116 are connected by a gear pair, the magnetic bead bottle 82 can rotate on its own as the reagent kit 78 rotates, thus achieving the effect of mixing the magnetic bead reagent.

[0138] In the optional technical solution of this embodiment, the reagent tray mechanism 1 further includes a retaining ring 55 disposed on the inner side wall 59 of the reagent pot 8 and used to cooperate with the reagent kit 78. The retaining ring 55 is provided with a notch 56, which corresponds to the automatic replacement port 11.

[0139] In this embodiment, a retaining ring 55 is installed on the inner sidewall 59 of the reagent pot 8, positioned directly above the spring piece 57 of the reagent bottle holder 79, to prevent the reagent kit 78 from jumping up during mixing. The retaining ring 55 has a notch 56, giving it a C-shaped structure. The notch 56 corresponds to the automatic replacement port 11, providing an entry point for the automatic loading and unloading of the reagent kit 78 on the outer rotating disk 6.

[0140] In the optional technical solution of this embodiment, both the first reagent position 15 and the second reagent position 16 are slots, and the slots have opposing first and second sidewalls 59. The first sidewall 59 is used to engage with the spring piece 57 of the reagent bottle holder 79, and the second sidewall 59 is used to engage with the buckle 58 of the reagent bottle holder 79. Specifically, the second sidewall 59 is provided with a clearance opening to avoid the sector-shaped mixing gear 116. The buckle 58 is engaged with the upper wall of the clearance opening, that is, the lower end face 34 of the outer ring turntable 6 corresponding to the clearance opening. The spring piece 57 of the reagent bottle holder 79 generates a spring force that pushes the reagent kit 78 closer to the center of the outer ring turntable 6 through deformation, ensuring that the reagent bottle holder 79 is tangent to the outer ring turntable 6 and ensuring the center distance between the magnetic bead bottle 82 and the sector-shaped mixing gear 116, thereby ensuring effective meshing between the two to achieve the purpose of mixing.

[0141] In this preferred embodiment, the outer turntable 6 has 40 first reagent positions 15 evenly distributed circumferentially. Driven by the outer ring drive device, the corresponding reagent kit 78 is conveyed to the reagent suction port 12 or the automatic replacement port 11. The reagent suction port 12 provides the necessary reagents for the sample to be tested, and the automatic replacement port 11 facilitates the clamping mechanism 3 to remove the empty reagent kit 78 or put in a new reagent kit 78. The inner turntable 7 stores new reagent kits 78 and temporarily stores the reagent kits 78 that have been consumed on the outer turntable 6. The inner turntable 7 has 10+1 second reagent positions 16 evenly distributed circumferentially, which can hold 10 reagent kits 78 to be used. The extra second reagent position 16 is a temporary storage position for reagent kits 78. Driven by the inner ring drive device, the empty second reagent position 16 and the corresponding reagent kit 78 to be used are conveyed to the automatic replacement port 11, so that the clamping mechanism 3 can remove the new reagent kit 78 or put in the empty reagent kit 78.

[0142] This embodiment provides a method for online loading and automatic replacement of reagent kits, using the aforementioned online loading and automatic replacement system for reagent kits, including the following steps:

[0143] S1, the reagent kit 78 to be aspirated is loaded into the first reagent position 15 through the outer ring loading port 9, and the reagent kit 78 to be loaded into the second reagent position 16 through the inner ring loading port 10, and at least one second reagent position 16 is empty.

[0144] S2, Read the RFID information of reagent kit 78 on the first reagent position 15, and read the RFID information of reagent kit 78 on the second reagent position 16;

[0145] S3, automatically replace the empty reagent kit 78 on the first reagent position 15 with the reagent kit 78 on the second reagent position 16 that has the same detection item.

[0146] As a further technical solution, step S2, reading the RFID information of reagent kit 78 on the second reagent bit 16, includes the following steps:

[0147] S211, open the automatic switching port 11;

[0148] S212, the inner rotating disk 7 rotates the reagent kit 78 to be read to the automatic replacement port 11;

[0149] S213, the clamping mechanism 3 picks up the reagent kit 78 to be read and transports it to the inner RFID reader 40 through the transport mechanism 2 to read the RFID information and match it with the original second reagent position 16.

[0150] S214, after reading, return to the original second reagent slot 16;

[0151] S215, repeat S212 to S214 to complete the RFID information reading of all reagent kits 78.

[0152] In the optional technical solution of this embodiment, step S2, reading the RFID information of reagent kit 78 on the first reagent position 15, includes the following steps:

[0153] S221, the outer ring turntable 6 rotates the reagent kit 78 to be read to the outer ring RFID reader 39;

[0154] S222, the outer ring RFID reader 39 reads the information of the reagent kit 78 to be read and matches it with the first reagent position 15;

[0155] S223, repeat S221~S222 to complete the RFID information reading of all reagent kits 78.

[0156] In the optional technical solution of this embodiment, step S3 includes the following steps:

[0157] S31, open the automatic switching port 11;

[0158] S32, the inner turntable 7 moves the empty second reagent position 16 to the automatic replacement port 11. After the reagent kit 78 on the first reagent position 15 is completely aspirated or after mixing is completed, the outer turntable 6 moves the empty reagent kit 78 on the first reagent position 15 to the automatic replacement port 11.

[0159] S33, the clamping mechanism 3 picks up the empty reagent kit 78 on the first reagent position 15 and transports it to the empty second reagent position 16 through the transport mechanism 2;

[0160] S34, the conveying mechanism 2 lifts the clamping mechanism 3, and when the outer turntable 6 receives a reagent aspiration request from the controller, the outer turntable 6 rotates the designated reagent kit 78 to the reagent aspiration port 12, or when the outer turntable 6 receives a mixing request from the controller, the outer turntable 6 rotates to mix the reagent.

[0161] S35, the inner turntable 7 moves the reagent kit 78 with the same detection item on the second reagent position 16 to the automatic replacement port 11, and when the outer turntable 6 receives a reagent aspiration request from the controller, after the reagent kit 78 on the first reagent position 15 has been aspirated, or when the outer turntable 6 receives a mixing request from the controller, after the mixing is completed, the outer turntable 6 moves the empty first reagent position 15 to the automatic replacement port 11.

[0162] S36, the clamping mechanism 3 picks up the reagent kit 78 on the second reagent position 16 and transports it to the empty first reagent position 15 via the transport mechanism 2;

[0163] S37, repeat S32~S36 to complete the replacement of the reagent kit 78 that has been aspirated on the first reagent position 15 with the reagent kit 78 waiting to be loaded on the second reagent position 16.

[0164] S38, the conveying mechanism 2 lifts the clamping mechanism 3 and closes the automatic replacement port 11.

[0165] Specifically, the outer ring drive device drives the outer ring turntable 6 to rotate, and simultaneously loads the reagent kits 78 to be aspirated onto the first reagent positions 15 through the outer ring loading port 9. Preferably, the outer ring turntable 6 has forty first reagent positions 15, at which time the outer ring turntable 6 can be filled with forty reagent kits 78, but it can also be left unfilled. The inner ring drive device drives the inner ring turntable 7 to rotate, and simultaneously loads the reagent kits 78 to be loaded onto the second reagent positions 16 through the inner ring loading port 10, and at least one second reagent position 16 is kept empty. Preferably, the inner ring turntable 7 has eleven second reagent positions 16, at which time the inner ring turntable 7 can hold ten reagent kits 78, keeping one second reagent position 16 empty, but the number of reagent kits 78 can also be less than ten. After the outer ring turntable 6 and the inner ring turntable 7 are loaded, the instrument starts the test, and performs RFID information reading on the reagent kits 78 on the outer ring turntable 6 and on the reagent kits 78 on the inner ring turntable 7. These two processes can be performed simultaneously or sequentially.

[0166] The specific process for reading RFID information from reagent kits 78 on the outer ring turntable 6 is as follows: the outer ring turntable 6 is driven to rotate by the outer ring drive device, and the reagent kits 78 on the first reagent position 15 are sequentially moved to the outer ring RFID reader 39 for RFID information reading. After reading, each reagent kit 78 is matched with its first reagent position 15, and then the RFID information of the next reagent kit 78 is read, until all reagent kits 78 have completed RFID information reading.

[0167] The specific process for reading RFID information from reagent kits 78 on the inner turntable 7 is as follows: the automatic replacement port 11 is opened by the automatic opening and closing window mechanism 4, the inner turntable 7 is driven to rotate by the inner drive device, and the reagent kits 78 on the second reagent position 16 are sequentially moved to the automatic replacement port 11. The transport mechanism 2 drives the clamping mechanism 3 to extend into the automatic replacement port 11, and the clamping mechanism 3 clamps the reagent kits 78 at the automatic replacement port 11. The transport mechanism 2 transports the clamping mechanism 3 to the outer RFID reader 39 for RFID information reading. After reading, each reagent kit 78 is matched with its corresponding second reagent position 16. At the same time, the transport mechanism 2 drives the clamping mechanism 3 to put the reagent kit 78 back to its original position, and then the RFID information reading of the next reagent kit 78 is performed until all reagent kits 78 have completed RFID information reading.

[0168] After the above process is completed, the controller can issue a request to aspirate the reagent in the designated reagent kit 78 on the outer ring turntable 6, and drive the outer ring turntable 6 to rotate so that the designated reagent kit 78 is moved to the reagent suction port 12; or the controller can issue a request to mix the reagent in the reagent kit 78 on the outer ring turntable 6, and drive the outer ring turntable 6 to rotate to mix the reagent; after the reagent in the reagent kit 78 on the outer ring turntable 6 has been aspirated or the mixing is completed, the controller can issue a request to automatically replace the reagent kit 78 that has been aspirated in the first reagent position 15 with the reagent kit 78 with the same detection item in the second reagent position 16.

[0169] The automatic replacement process (i.e., automatic loading of reagent kit 78) is as follows: The automatic replacement port 11 is opened by the automatic opening and closing window mechanism 4; the outer ring drive device drives the outer ring turntable 6 to rotate and move the empty reagent kit 78 to the automatic replacement port 11; the inner ring drive device drives the inner ring turntable 7 to rotate and move the empty second reagent position 16 to the automatic replacement port 11. It should be noted that the above three processes can be performed simultaneously or in steps. After the above three processes are completed, the conveying mechanism 2 drives the clamping mechanism 3 to extend into the automatic replacement port 11, and the clamping mechanism 3 clamps the empty reagent kit 78 located at the automatic replacement port 11 on the outer ring turntable 6. The transport mechanism 2 drives the clamping mechanism 3 to load the empty reagent kit 78 onto the empty second reagent position 16 on the inner turntable 7. Then, the transport mechanism 2 drives the clamping mechanism 3 to lift and exit the automatic replacement port 11. Since the clamping mechanism 3 has exited the automatic replacement port 11, the controller can issue a request to aspirate the reagent in the designated reagent kit 78 on the outer turntable 6. The outer turntable 6 is driven to rotate via the outer turntable drive device to move the designated reagent kit 78 to the reagent suction port 12. Alternatively, the controller can issue a request to mix the reagent in the reagent kit 78 on the outer turntable 6. The outer turntable 6 is driven to rotate via the outer turntable drive device to mix the reagent. It should be noted that after the clamping mechanism 3 lifts and exits the automatic replacement port 11, the controller can issue a request to aspirate the reagent or to mix the reagent, or it can choose not to issue a request.

[0170] After the clamping mechanism 3 lifts and exits the automatic replacement port 11, and the controller does not issue a request to aspirate reagents or mix, the inner drive device drives the inner turntable 7 to rotate and move the reagent kit 78 with the same test item on the second reagent position 16 to the automatic replacement port 11. The transport mechanism 2 drives the clamping mechanism 3 to extend into the automatic replacement port 11. The clamping mechanism 3 clamps the reagent kit 78 with the same test item on the inner turntable 7 located at the automatic replacement port 11. The transport mechanism 2 drives the clamping mechanism 3 to load the reagent kit 78 with the same test item onto the empty first reagent position 15 on the outer turntable 6. Then, the transport mechanism 2 drives the clamping mechanism 3 to lift and exit the automatic replacement port 11.

[0171] After the clamping mechanism 3 lifts and exits the automatic replacement port 11, the controller issues a request to aspirate reagents or mix the reagents. The inner drive device drives the inner turntable 7 to rotate and move the reagent kit 78 with the same test item on the second reagent position 16 to the automatic replacement port 11. After the reagent kit 78 on the outer turntable 6 has been aspirated or mixed, the transport mechanism 2 drives the clamping mechanism 3 to extend into the automatic replacement port 11. The clamping mechanism 3 clamps the reagent kit 78 with the same test item on the inner turntable 7 located at the automatic replacement port 11. The transport mechanism 2 drives the clamping mechanism 3 to load the reagent kit 78 with the same test item onto the empty first reagent position 15 on the outer turntable 6. Then, the transport mechanism 2 drives the clamping mechanism 3 to lift and exit the automatic replacement port 11.

[0172] After the replacement of the empty reagent kit 78 on the first reagent position 15 with the reagent kit 78 waiting to be loaded on the second reagent position 16 is completed, the automatic replacement port 11 is closed by the automatic opening and closing window mechanism 4, and the replacement process ends.

[0173] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A reagent kit online loading and automatic replacement system, characterized in that, include: The reagent tray mechanism (1), the transport mechanism (2), the clamping mechanism (3), and the automatic opening and closing window mechanism (4) are included. The reagent tray mechanism (1) includes a reagent tray cover (5), an outer ring turntable (6), an inner ring turntable (7), and a reagent pot (8) for low-temperature storage of reagent kits (78). The reagent tray cover (5) is placed on the reagent pot (8). The outer ring turntable (6) and the inner ring turntable (7) are both located inside the reagent pot (8) and can rotate relative to each other along the same axis. The reagent tray cover (5) is provided with an outer ring loading port (9), an inner ring loading port (10), an automatic replacement port (11), and a reagent suction port (12). The outer ring loading port (9) and the reagent suction port (12) are both corresponding to the outer ring turntable (6). The inner ring loading port (10) is corresponding to the inner ring turntable (7). The automatic replacement port (11) is corresponding to both the inner ring turntable (7) and the outer ring turntable (6). An outer ring cover (13) is provided at the outer ring loading port (9), and an inner ring cover (14) is provided at the inner ring loading port (10). The automatic opening and closing window mechanism (4) is provided on the reagent tray cover (5) and is used to close or open the automatic replacement port (11). The outer turntable (6) is provided with a plurality of first reagent positions (15) for loading the reagent kit (78) along the circumferential direction, and the inner turntable (7) is provided with a plurality of second reagent positions (16) for loading the reagent kit (78) along the circumferential direction. The clamping mechanism (3) is used to clamp the reagent kit (78), and the transport mechanism (2) is disposed on the reagent tray cover (5) and is used to drive the clamping mechanism (3) to move between the first reagent position (15) and the second reagent position (16); The automatic opening and closing window mechanism (4) includes a window cover (41), an auxiliary guide rail (42), a first motor (43), a crank (44), a connecting rod (45), a linear guide rail (46), a limiting baffle (47), and a limiting optocoupler (48). The auxiliary guide rail (42) and the linear guide rail (46) are arranged opposite to each other and are both fixed on the reagent tray cover (5). The first motor (43) is fixed on the reagent tray cover (5) by a motor bracket (63), and the output end of the first motor (43) is connected to the crank (44). One end of the connecting rod (45) is hinged to the window cover (41), and the other end is hinged to the crank (44). The limiting baffle (47) is arranged on the crank (44), and the limiting optocoupler (45) is fixed on the crank (44). 8) The reagent tray cover (5) is set on and cooperates with the limiting baffle (47). When there is a need to replace the reagent kit (78), the crank (44) rotates with the output end of the first motor (43) and drives the connecting rod (45) to move, thereby pushing or pulling the window cover (41) along the linear guide rail (46) and the auxiliary guide rail (42) to reciprocate. At the same time, when there is no need to replace the reagent kit (78), the automatic replacement port (11) remains closed. The conveying mechanism (2) includes an X-axis conveying device (53) and a Z-axis conveying device (54). The X-axis transport device (53) is connected to the reagent tray cover (5) via a support member, the Z-axis transport device (54) is connected to the X-axis transport device (53), and the clamping mechanism (3) is connected to the Z-axis transport device (54).

2. The online loading and automatic replacement system for reagent kits according to claim 1, characterized in that, The reagent tray mechanism (1) also includes a base plate (17), an inner ring drive device, and an outer ring drive device; The reagent pot (8) has a bottom wall (18), which is fixedly connected to the bottom plate (17) and has a gap between it and the bottom plate (17); The inner ring drive device and the outer ring drive device are both mounted on the base plate (17) and are located at the interval. The bottom wall (18) has a through hole. The inner ring drive device passes through the through hole to drive the inner ring turntable (7) to rotate, and the outer ring drive device passes through the through hole to drive the outer ring turntable (6) to rotate.

3. The online loading and automatic replacement system for reagent kits according to claim 2, characterized in that, The inner ring drive device includes a main shaft (19), an inner ring bushing (20), an inner ring bearing (21), an inner ring connecting flange (22), an inner ring motor (23), an inner ring synchronous pulley (24), and an inner ring transmission belt (25). One end of the main shaft (19) is fixedly connected to the base plate (17), and the other end passes through the through hole. The inner ring bushing (20) is rotatably connected to the main shaft (19) through the inner ring bearing (21). The inner ring turntable (7) is connected to the inner ring bushing (20) through the inner ring connecting flange (22). The inner ring motor (23) is fixedly connected to the base plate (17), the inner ring synchronous pulley (24) is fixedly connected to the inner ring bushing (20), and the output end of the inner ring motor (23) is connected to the inner ring synchronous pulley (24) through the inner ring transmission belt (25).

4. The online loading and automatic replacement system for reagent kits according to claim 3, characterized in that, The outer ring drive device includes an outer ring bushing (26), an outer ring bearing (27), an outer ring connecting flange (28), an outer ring motor (29), an outer ring synchronous pulley (30), an outer ring transmission belt (31), and an outer ring reduction gear (32). The outer ring bushing (26) is rotatably connected to the inner ring bushing (20) through the outer ring bearing (27), and the outer ring turntable (6) is connected to the outer ring bushing (26) through the outer ring connecting flange (28). The outer ring motor (29) is fixedly connected to the base plate (17), the outer ring synchronous pulley (30) is fixedly connected to the outer ring bushing (26), the output end of the outer ring motor (29) is connected to the outer ring reduction gear (32), and the outer ring reduction gear (32) is connected to the outer ring synchronous pulley (30) through the outer ring transmission belt (31).

5. The online loading and automatic replacement system for reagent kits according to claim 4, characterized in that, The reagent disk mechanism (1) further includes an inner ring code disk (33), an inner ring zero position optocoupler, an inner ring code tooth optocoupler, an outer ring code disk (36), an outer ring zero position optocoupler (37), and an outer ring code tooth optocoupler (38). The inner ring connecting flange (22) is connected to the upper end of the inner ring bushing (20), the inner ring code disk (33) is connected to the lower end of the inner ring bushing (20), and the inner ring zero position optocoupler and the inner ring code tooth optocoupler are both connected to the base plate (17) and cooperate with the inner ring code disk (33). The outer ring connecting flange (28) is connected to the upper end of the outer ring bushing (26), the outer ring code disk (36) is connected to the lower end of the outer ring bushing (26), the outer ring zero position optocoupler (37) and the outer ring code tooth optocoupler (38) are both connected to the base plate (17) and cooperate with the outer ring code disk (36).

6. The online loading and automatic replacement system for reagent kits according to claim 1, characterized in that, It also includes an outer ring RFID reader (39) and an inner ring RFID reader (40). The outer ring RFID reader (39) is located inside the reagent pot (8) and is used to read the RFID information of the reagent kit (78) on the first reagent position (15). The inner ring RFID reader (40) is located on the reagent tray cover (5) and is used to read the RFID information of the reagent kit (78) on the second reagent position (16).

7. The online loading and automatic replacement system for reagent kits according to claim 1, characterized in that, The clamping mechanism (3) includes a drive device, a front gripper (49), a rear gripper (50), a cam (51), a roller, and a return spring (52). The front gripper (49) and the rear gripper (50) are arranged opposite to each other, and both the front gripper (49) and the rear gripper (50) are provided with rollers. The cam (51) is arranged between the two rollers. The driving device is used to drive the cam (51) to rotate. The cam (51) drives the two rollers to move the front gripper (49) and the rear gripper (50) away from each other by rotating. One end of the return spring (52) is connected to the front gripper (49) and the other end is connected to the rear gripper (50). The return spring (52) is used to drive the front gripper (49) and the rear gripper (50) to move closer to each other.

8. The online loading and automatic replacement system for reagent kits according to claim 7, characterized in that, The reagent kit (78) is provided with a first positioning part, and the front gripper (49) and the rear gripper (50) are each provided with a second positioning part that cooperates with the first positioning part for positioning.

9. The online loading and automatic replacement system for reagent kits according to claim 1, characterized in that, The transport mechanism (2) further includes an X-direction positioning buffer device and an X-direction positioning detection device disposed on the X-direction transport device (53), and a Z-direction positioning buffer device and a Z-direction positioning detection device disposed on the Z-direction transport device (54).

10. The online loading and automatic replacement system for reagent kits according to claim 1, characterized in that, The reagent tray mechanism (1) further includes a mixing device disposed in the reagent pot (8), which is used to mix the reagent kit (78).

11. The online loading and automatic replacement system for reagent kits according to claim 1, characterized in that, The reagent tray mechanism (1) further includes a retaining ring (55) disposed on the inner side wall (59) of the reagent pot (8) and used to cooperate with the reagent kit (78). The retaining ring (55) has a notch (56) that corresponds to the automatic replacement port (11).

12. The online loading and automatic replacement system for reagent kits according to claim 1, characterized in that, The reagent kit (78) has a spring (57) on one side and a buckle (58) on the other side. The first reagent position (15) and the second reagent position (16) are both slots, and the slots have opposing first sidewalls and second sidewalls. The first sidewall is used to engage with the spring (57) and the second sidewall is used to engage with the buckle (58).

13. A method for online loading and automatic replacement of reagent kits, using the online loading and automatic replacement system for reagent kits according to any one of claims 1-12, characterized in that, Including the following steps: S1, the reagent kit (78) to be aspirated is loaded into the first reagent position (15) through the outer ring loading port (9), and the reagent kit (78) to be loaded into the second reagent position (16) through the inner ring loading port (10), and at least one second reagent position (16) is empty; S2, read the RFID information of the reagent kit (78) on the first reagent position (15), and read the RFID information of the reagent kit (78) on the second reagent position (16); S3, automatically replace the kit (78) that was emptied on the first reagent position (15) with the kit (78) with the same detection item on the second reagent position (16).

14. The method for online loading and automatic replacement of the reagent kit according to claim 13, characterized in that, The step S2, which involves reading the RFID information of the reagent kit (78) on the second reagent bit (16), includes the following steps: S211, open the automatic switching port (11); S212, the inner turntable (7) rotates the reagent kit (78) to be read to the automatic replacement port (11); S213, the clamping mechanism (3) picks up the reagent kit (78) to be read and transports it to the inner RFID reader (40) through the transport mechanism (2) to read the RFID information and match it with the original second reagent position (16); S214, after reading, return to the original second reagent position (16). S215, repeat steps S212~S214 to complete the RFID information reading of all reagent kits (78).

15. The method for online loading and automatic replacement of the reagent kit according to claim 13, characterized in that, The step S2, which involves reading the RFID information of the reagent kit (78) on the first reagent bit (15), includes the following steps: S221, the outer ring turntable (6) moves the reagent kit (78) to be read to the outer ring RFID reader (39); S222, the outer ring RFID reader (39) reads the RFID information of the reagent kit (78) to be read and matches it with the first reagent bit (15); S223, repeat steps S221~S222 to complete the RFID information reading of all reagent kits (78).

16. The method for online loading and automatic replacement of reagent kits according to claim 13, characterized in that, Step S3 includes the following steps: S31, open the automatic switching port (11); S32, the inner turntable (7) moves the empty second reagent position (16) to the automatic replacement port (11). After the reagent kit (78) on the first reagent position (15) is completely aspirated or after mixing is completed, the outer turntable (6) moves the empty reagent kit (78) on the first reagent position (15) to the automatic replacement port (11). S33, the clamping mechanism (3) picks up the empty reagent kit (78) on the first reagent position (15) and transports it to the empty second reagent position (16) through the transport mechanism (2). S34, the conveying mechanism (2) lifts the clamping mechanism (3), and when the outer turntable (6) receives a reagent aspiration request from the controller, the outer turntable (6) rotates the designated reagent kit (78) to the reagent aspiration port (12), or when the outer turntable (6) receives a mixing request from the controller, the outer turntable (6) rotates to mix the reagent. S35, the inner turntable (7) moves the reagent kit (78) with the same test item on the second reagent position (16) to the automatic replacement port (11), and when the outer turntable (6) receives the reagent aspiration request from the controller, after the reagent kit (78) on the first reagent position (15) has been aspirated, or when the outer turntable (6) receives the mixing request from the controller, after the mixing is completed, the outer turntable (6) moves the empty first reagent position (15) to the automatic replacement port (11). S36, the clamping mechanism (3) picks up the reagent kit (78) on the second reagent position (16) and transports it to the empty first reagent position (15) by the transport mechanism (2). S37, repeat steps S32~S36 to complete the replacement of the reagent kit (78) that has been aspirated on the first reagent position (15) with the reagent kit (78) waiting to be loaded on the second reagent position (16); S38, the conveying mechanism (2) lifts the clamping mechanism (3) and closes the automatic replacement port (11).

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