A grinding system for preparing ultra-fine and highly active tricalcium phosphate

Abstract

The invention discloses a grinding system for preparing ultrafine high-activity tricalcium phosphate, comprising: an acquisition module, which evenly divides a scanned image into a plurality of monitoring sub-areas, and obtains the high-activity tricalcium phosphate particle size data in each corresponding monitoring sub-area; an analysis module, which obtains the high-activity tricalcium phosphate particle size data in the monitoring sub-areas, analyzes the data, and compares and integrates the obtained particle sizes of adjacent areas; a processing module, which receives a regional fusion signal and a regional segmentation signal sent by the analysis module, and if a regional fusion signal is obtained, two areas with a small difference are merged to obtain a new monitoring sub-area, and the new monitoring sub-area is compared with the next area; the particle size of the high-activity tricalcium phosphate obtained by grinding according to the invention meets the process standard, has a small particle size difference, and has good uniformity.

Description

Technical Field

[0001] The invention relates to the technical field of tricalcium phosphate, and in particular to a grinding system for preparing ultrafine high-activity tricalcium phosphate. Background Art

[0002] Tricalcium phosphate is a widely used chemical product. It is insoluble in water and ethanol, but soluble in acid. It is commonly found in human bones and is one of the daily calcium sources for organisms. In the food field, it can be used as an anti-caking agent, pH regulator, buffer, condiment, meat additive, etc. In the medical field, β-tricalcium phosphate can be widely used in joint and spinal fusion, limb trauma, oral and maxillofacial surgery, cardiovascular surgery, and filling periodontal cavities, etc. It can be seen that in daily life, tricalcium phosphate is widely used.

[0003] In the prior art, tricalcium phosphate needs to be ground during the production process to ensure that its particle size meets the process requirements. However, there is currently no effective monitoring of the grinding process of tricalcium phosphate. This will result in the tricalcium phosphate product having poor uniformity and a large difference in particle size between materials, although most of them meet the process requirements. Summary of the invention

[0004] The purpose of the present invention is to solve the above-mentioned problems of the background technology and to provide a grinding system for preparing ultra-fine high-activity tricalcium phosphate.

[0005] The purpose of the present invention can be achieved through the following technical solutions:

[0006] A grinding system for preparing ultrafine high-activity tricalcium phosphate, comprising:

[0007] The acquisition module obtains a scanned image of the high-activity tricalcium phosphate in the grinding chamber through a scanning device, sets a plane coordinate system for the plane where the scanned image is located, evenly divides the scanned image into a number of monitoring sub-areas, and obtains the particle size data of the high-activity tricalcium phosphate in each corresponding monitoring sub-area;

[0008] The analysis module obtains the particle size data of high-activity tricalcium phosphate in the monitoring sub-area, analyzes the data, and compares and integrates the obtained particle sizes of adjacent areas;

[0009] The processing module receives the regional fusion signal and the regional segmentation signal sent by the analysis module. If a regional fusion signal is obtained, two regions with small differences are merged to obtain a new monitoring sub-region, and the new monitoring sub-region is compared with the next region.

[0010] The grinding control module obtains the new monitoring sub-area after fusion, adds the high-activity tricalcium phosphate particle size distribution value Zf of the combined monitoring sub-area and takes the average value to obtain the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area, compares it with the corresponding threshold value, and then generates a grinding control signal.

[0011] As a further solution of the present invention: the specific working process of the analysis module is as follows:

[0012] Step 1: Obtain the average particle size of high-activity tricalcium phosphate in the monitoring sub-area and the average thickness of the high-activity tricalcium phosphate particle size in the area, and mark them as Zl and Zh respectively;

[0013] Step 2: Using the formula Zf=Zl×a1+Zh×a2, calculate the particle size distribution value Zf of the high-activity tricalcium phosphate in the area;

[0014] Step 3: Obtain the particle size distribution value Zf of high-activity tricalcium phosphate in each monitoring sub-area i , i is a non-zero positive integer; i = 1, ..., n; then use the formula Zc = | Zf i -Zf i-1 |, calculate the grinding uniformity Zc of high-activity tricalcium phosphate in two adjacent monitoring sub-areas;

[0015] Step 4: Compare the grinding uniformity Zc of the high-activity tricalcium phosphate with the grinding uniformity threshold of the high-activity tricalcium phosphate.

[0016] As a further solution of the present invention: if the grinding uniformity Zc of the high-activity tricalcium phosphate is less than the grinding uniformity threshold of the high-activity tricalcium phosphate, a regional fusion signal is obtained.

[0017] As a further solution of the present invention: if the grinding uniformity Zc of the high-activity tricalcium phosphate is greater than the grinding uniformity threshold of the high-activity tricalcium phosphate, a region segmentation signal is obtained.

[0018] As a further solution of the present invention: the specific working process of the grinding control module is as follows:

[0019] Step 1: Add the high-activity tricalcium phosphate particle size distribution values ​​Zf of the combined monitoring sub-areas and take the average value to obtain the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area;

[0020] Step 2: Compare the particle size distribution value J1 of the high-activity tricalcium phosphate in the new monitoring sub-area with the particle size distribution value of the high-activity tricalcium phosphate in the new monitoring sub-area.

[0021] As a further solution of the present invention: if the high-activity tricalcium phosphate particle size distribution value J1 of the new monitoring sub-area is greater than the high-activity tricalcium phosphate particle size distribution value of the new monitoring sub-area, a continue grinding signal is generated.

[0022] As a further solution of the present invention: if the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area is smaller than the high-activity tricalcium phosphate particle size distribution value of the new monitoring sub-area, a unloading signal is generated and the high-activity tricalcium phosphate in the area is taken out.

[0023] As a further solution of the present invention: when a continuous grinding signal is generated, the pressure value of the grinding head when the high-activity tricalcium phosphate is ground, and the pressure fluctuation frequency corresponding to the pressure value are obtained, and are marked as Py and Pp respectively; at the same time, the speed value of the grinding head when the high-activity tricalcium phosphate is ground, and the speed fluctuation frequency corresponding to the speed value are also obtained, and are marked as Zy and Zp respectively;

[0024] Using the formula The grinding value Y1 of the current high-activity tricalcium phosphate is calculated; wherein b1, b2, b3, and b4 are all proportional coefficients, b1 is 0.843, b2 is 0.412, b3 is 0.951, and b4 is 0.852;

[0025] And, obtain the mean particle size Zl of the new monitoring sub-area after fusion, and then use the formula Zl-Zlb|=K*Yl*t to calculate and predict the grinding end time t under the grinding working conditions.

[0026] Beneficial effects of the present invention:

[0027] The present invention scans and analyzes the particle size of high-activity tricalcium phosphate during the grinding process to determine whether the particle size meets the process standard and the uniformity of the particle size distribution of the high-activity tricalcium phosphate after grinding. Then, a sorting and fusion analysis is performed to take out qualified high-activity tricalcium phosphate particles, thereby reducing the time and efficiency of later grinding. The high-activity tricalcium phosphate with unqualified particle size is further ground, and it is ensured that the particle size of the high-activity tricalcium phosphate processed in batches meets the process standard after grinding, so that the particle size of the high-activity tricalcium phosphate obtained by grinding meets the process standard, the particle size difference is small, and the uniformity is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] The present invention will be further described below in conjunction with the accompanying drawings.

[0029] Figure 1 It is a system block diagram of the present invention. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Example 1

[0032] See also Figure 1 As shown, the present invention is a grinding system for preparing ultra-fine high-activity tricalcium phosphate, including a collection module and an analysis module;

[0033] The acquisition module obtains a scanning image of the high-activity tricalcium phosphate in the grinding chamber through a scanning device, sets a plane coordinate system for the plane where the scanning image is located, evenly divides the scanning image into a number of monitoring sub-areas, and marks the monitoring sub-areas as i, where i is a non-zero positive integer; i=1, ..., n; and obtains the particle size data of the high-activity tricalcium phosphate in each corresponding monitoring sub-area;

[0034] The high-activity tricalcium phosphate is scanned by a three-dimensional laser scanning device to obtain point cloud data of the high-activity tricalcium phosphate, and the particle size of the high-activity tricalcium phosphate is obtained based on the point cloud data;

[0035] The analysis module obtains the particle size data of high-activity tricalcium phosphate in the monitoring sub-area, analyzes the data, and compares and integrates the obtained particle sizes of adjacent areas;

[0036] The specific working process of this analysis module is as follows:

[0037] Step 1: Obtain the average particle size of high-activity tricalcium phosphate in the monitoring sub-area and the average thickness of the high-activity tricalcium phosphate particle size in the area, and mark them as Zl and Zh respectively;

[0038] Step 2: Use the formula Zf=Zl×a1+Zh×a2 to calculate the particle size distribution value Zf of the high-activity tricalcium phosphate in the area, where a1, a2, and a3 are coefficient factors, a1 is 0741, and a2 is 0.285;

[0039] Step 3: Obtain the particle size distribution value Zf of high-activity tricalcium phosphate in each monitoring sub-area i , i is a non-zero positive integer; i = 1, ..., n; then use the formula Zc = | Zf i -Zf i-1 |, calculate the grinding uniformity Zc of high-activity tricalcium phosphate in two adjacent monitoring sub-areas;

[0040] Step 4: Compare the grinding uniformity Zc of the high-activity tricalcium phosphate with the grinding uniformity threshold of the high-activity tricalcium phosphate:

[0041] If the grinding uniformity Zc of high-activity tricalcium phosphate is less than the grinding uniformity threshold of high-activity tricalcium phosphate, it means that the particle sizes of high-activity tricalcium phosphate in two connected regions are relatively small, and they can be fused as a whole to proceed to the next step, and obtain a regional fusion signal;

[0042] If the grinding uniformity Zc of high-activity tricalcium phosphate is greater than the grinding uniformity threshold of high-activity tricalcium phosphate, it means that the particle sizes of high-activity tricalcium phosphate in two connected regions are quite different and cannot be fused as a whole to proceed to the next step, thereby obtaining a region segmentation signal;

[0043] The processing module receives the regional fusion signal and the regional segmentation signal sent by the analysis module. If a regional fusion signal is obtained, two regions with small differences are merged to obtain a new monitoring sub-region, and the new monitoring sub-region is compared with the next region.

[0044] An example of the processing module working is as follows:

[0045] If the particle size distribution value Zf of the high-activity tricalcium phosphate in the monitoring sub-area No. 1 is Zf1, if the particle size distribution value Zf of the high-activity tricalcium phosphate in the monitoring sub-area No. 2 is Zf2, if the particle size distribution value Zf of the high-activity tricalcium phosphate in the monitoring sub-area No. 3 is Zf3, if the particle size distribution value Zf of the high-activity tricalcium phosphate in the monitoring sub-area No. 4 is Zf4, when |Zf 2 -Zf 1 | is less than the grinding uniformity threshold of high-activity tricalcium phosphate, then the fusion is Zf 21 area, and then |Zf 21 -Zf 3 |Compared with the grinding uniformity threshold of high-activity tricalcium phosphate, if it is less than, further fusion is obtained to obtain Zf 321 area, and then |Zf 321 -Zf 4 | is compared with the threshold, and then compared with the next monitoring sub-region in turn; if it is greater than, the monitoring sub-region No. 1 is merged with the monitoring sub-region No. 2 to obtain Zf 21 area, and at the same time, compare the monitoring sub-area No. 3 with the following monitoring sub-areas;

[0046] The grinding control module obtains the fused new monitoring sub-area, adds the high-activity tricalcium phosphate particle size distribution values ​​Zf of the combined monitoring sub-areas and takes the average value to obtain the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area, compares it with the corresponding threshold value, and then generates a grinding control signal;

[0047] The specific working process of the grinding control module is as follows:

[0048] Step 1: Add the high-activity tricalcium phosphate particle size distribution values ​​Zf of the combined monitoring sub-areas and take the average value to obtain the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area;

[0049] Step 2: Compare the particle size distribution value J1 of the high-activity tricalcium phosphate in the new monitoring sub-area with the particle size distribution value of the high-activity tricalcium phosphate in the new monitoring sub-area;

[0050] If the particle size distribution value J1 of the high-activity tricalcium phosphate in the new monitoring sub-region is greater than the particle size distribution value of the high-activity tricalcium phosphate in the new monitoring sub-region, a signal for continuing grinding is generated;

[0051] If the particle size distribution value J1 of the high-activity tricalcium phosphate in the new monitoring sub-area is smaller than the particle size distribution value of the high-activity tricalcium phosphate in the new monitoring sub-area, a discharge signal is generated, and the high-activity tricalcium phosphate in the area can be taken out;

[0052] Step 3: When a continuing grinding signal is generated, the pressure value of the grinding head when the high-activity tricalcium phosphate is ground, and the pressure fluctuation frequency corresponding to the pressure value are obtained, and are marked as Py and Pp respectively; at the same time, the speed value of the grinding head when the high-activity tricalcium phosphate is ground, and the speed fluctuation frequency corresponding to the speed value are also obtained, and are marked as Zy and Zp respectively;

[0053] Using the formula The grinding value Y1 of the current high-activity tricalcium phosphate is calculated; wherein b1, b2, b3, and b4 are all proportional coefficients, b1 is 0.843, b2 is 0.412, b3 is 0.951, and b4 is 0.852;

[0054] And, obtain the average particle size Zl of the new monitoring sub-area after fusion, and then use the formula |Zl-Zlb|=K*Yl*t to calculate the predicted grinding end time t under the grinding working conditions; where Zlb is the parameter value of the high-activity tricalcium phosphate grinding process, K is the proportional coefficient, and K takes a value of 3.02.

[0055] Example 2

[0056] Based on the above-mentioned embodiment 1, a working method of a grinding system for preparing ultrafine high-activity tricalcium phosphate of the present invention comprises the following steps:

[0057] Step 1: Obtain a scanning image of the high-activity tricalcium phosphate in the grinding chamber by means of a scanning device, set a plane coordinate system for the plane where the scanning image is located, evenly divide the scanning image into a number of monitoring sub-areas, and mark the monitoring sub-areas as i, where i is a non-zero positive integer; i=1, ..., n; and obtain the particle size data of the high-activity tricalcium phosphate in each corresponding monitoring sub-area;

[0058] Step 2: Obtain the particle size data of high-activity tricalcium phosphate in the monitoring sub-area, analyze the data, and compare and integrate the obtained particle sizes of adjacent areas;

[0059] Step 3: Receive the regional fusion signal and regional segmentation signal sent by the analysis module. If a regional fusion signal is obtained, merge the two regions with smaller differences to obtain a new monitoring sub-region, and compare it with the next region;

[0060] Step 4: The grinding control system obtains the new monitoring sub-area after fusion, adds the high-activity tricalcium phosphate particle size distribution value Zf of the combined monitoring sub-area and takes the average value to obtain the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area, compares it with the corresponding threshold value, and then generates a grinding control signal.

[0061] The above is a detailed description of an embodiment of the present invention, but the content is only a preferred embodiment of the present invention and cannot be considered to limit the scope of implementation of the present invention. All equivalent changes and improvements made within the scope of the present invention should still fall within the scope of the patent coverage of the present invention.

Claims

1. A grinding system for preparing ultrafine high-activity tricalcium phosphate, characterized in that: include: The acquisition module obtains a scanned image of the high-activity tricalcium phosphate in the grinding chamber through a scanning device, sets a plane coordinate system for the plane where the scanned image is located, evenly divides the scanned image into several monitoring sub-areas, and obtains the particle size data of the high-activity tricalcium phosphate in each corresponding monitoring sub-area; The analysis module obtains the particle size data of high-activity tricalcium phosphate in the monitoring sub-area, analyzes the data, and compares and integrates the obtained particle sizes of adjacent areas; The processing module receives the regional fusion signal and the regional segmentation signal sent by the analysis module. If a regional fusion signal is obtained, two adjacent regions with a small difference in particle size distribution values ​​are merged to obtain a new monitoring sub-region, and the new monitoring sub-region is compared with the next region. The grinding control module obtains the fused new monitoring sub-area, adds the high-activity tricalcium phosphate particle size distribution values ​​Zf of the combined monitoring sub-areas and takes the average value to obtain the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area, compares it with the corresponding threshold value, and then generates a grinding control signal; The specific working process of the analysis module is as follows: Step 1: Obtain the average particle size of high-activity tricalcium phosphate and the average thickness of high-activity tricalcium phosphate in the monitoring sub-area, and mark them as Z l and Zh respectively; Step 2: Calculate the particle size distribution value Zf of the high-activity tricalcium phosphate in the region using the formula Zf=Zl×a1+Zh×a2; a1 and a2 are coefficient factors; a1 is 0.741, and a2 is 0.285; Step 3: Obtain the particle size distribution value Zf of high-activity tricalcium phosphate in each monitoring sub-area i , i is a non-zero positive integer; i = 1, ..., n; Then use the formula Zc=|Zf i -Zf i-1 |, calculate the grinding uniformity Zc of high-activity tricalcium phosphate in two adjacent monitoring sub-areas; Step 4: Compare the grinding uniformity Zc of the high-activity tricalcium phosphate obtained with the grinding uniformity threshold of the high-activity tricalcium phosphate; The specific working process of the grinding control module is as follows: Step 1: Add the high-activity tricalcium phosphate particle size distribution values ​​Zf of the combined monitoring sub-areas and take the average value to obtain the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area; Step 2: Compare the high-activity tricalcium phosphate particle size distribution value Jl of the new monitoring sub-area with the corresponding threshold.

2. A grinding system for preparing ultrafine high-activity tricalcium phosphate according to claim 1, characterized in that: If the grinding uniformity Zc of the high-activity tricalcium phosphate is less than the grinding uniformity threshold of the high-activity tricalcium phosphate, a regional fusion signal is obtained.

3. A grinding system for preparing ultrafine high-activity tricalcium phosphate according to claim 2, characterized in that: If the grinding uniformity Zc of the high-activity tricalcium phosphate is greater than the grinding uniformity threshold of the high-activity tricalcium phosphate, a region segmentation signal is obtained.

4. A grinding system for preparing ultrafine high-activity tricalcium phosphate according to claim 1, characterized in that: If the particle size distribution value J1 of the high-activity tricalcium phosphate in the new monitoring sub-area is greater than the corresponding threshold, a continue grinding signal is generated.

5. A grinding system for preparing ultrafine high-activity tricalcium phosphate according to claim 4, characterized in that: If the particle size distribution value J1 of the high-activity tricalcium phosphate in the new monitoring sub-area is less than the corresponding threshold, a discharge signal is generated and the high-activity tricalcium phosphate in the area is taken out.

6. A grinding system for preparing ultrafine high-activity tricalcium phosphate according to claim 5, characterized in that: When the continue grinding signal is generated, the pressure value of the grinding head when the high-activity tricalcium phosphate is ground, and the pressure fluctuation frequency corresponding to the pressure value are obtained, and are marked as Py and Pp respectively; at the same time, the speed value of the grinding head when the high-activity tricalcium phosphate is ground, and the speed fluctuation frequency corresponding to the speed value are also obtained, and are marked as Zy and Zp respectively; Using the formula The grinding value Y1 of the current high-activity tricalcium phosphate is calculated; wherein b1, b2, b3, and b4 are all proportional coefficients, b1 is 0.843, b2 is 0.412, b3 is 0.951, and b4 is 0.852; And, obtain the mean particle size Zl of the new monitoring sub-area after fusion, and then use the formula |Zl-Zlb|=K*Yl*t, the grinding end time t is predicted under the grinding working conditions, where Zlb is the parameter value of the high-activity tricalcium phosphate grinding process, K is the proportional coefficient, and the value of K is 3.02.

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