A positioning device for facilitating analysis of mouse vital signs

Abstract

The application relates to the technical field of pharmacological experiment equipment, and discloses a placement device beneficial to analyzing mouse vital signs, which comprises a first friction plate fixedly installed at one end of a horizontal rotating shaft and rotating with a glass cage, a gas type rotating structure installed above a bottom fixed base plate and abutting against the surface of the first friction plate, a spring type gas pressure control structure, and a driving motor installed above the bottom fixed base plate and capable of rotatingly driving the gas type rotating structure. The placement device beneficial to analyzing mouse vital signs controls the friction force of the driving motor to the glass cage during rotation through gas pressure, the rotation trend formed by the friction force to the glass cage is consistent with the movement direction of the mouse, so that the rolling friction resistance between the rotation connecting components between the glass cage and the support body is offset, and the activity degree of the mouse during movement is improved when the mouse is observed.

Description

TECHNICAL FIELD

[0001] The application relates to the technical field of pharmacological experiment equipment, in particular to a placing device beneficial to analyzing mouse vital signs. BACKGROUND

[0002] Mice are essential materials for life science research. In the process of drug experiments, mice are first taken as experimental objects. In the process of experiments, in order to observe the vital signs of mice within a period of time before and after injection of drugs, the mice need to be placed in a mouse placing device.

[0003] A novel experimental mouse cage is disclosed in Chinese Patent No. CN209089645U. The main structure of the cage includes a plastic bottom groove, a metal mesh cover used in cooperation with the plastic bottom groove, a metal bottom groove with the same shape as the plastic bottom groove is arranged in the plastic bottom groove, and the size of the metal bottom groove is smaller than that of the plastic bottom groove. An activity partition plate is arranged in the metal bottom groove, and the activity partition plate is detachably connected with the metal bottom groove. A partition plate clamping groove is arranged on both sides of the metal bottom groove and used in cooperation with the activity partition plate. The activity partition plate is detachably connected to the metal bottom groove through the partition plate clamping groove. The metal mesh cover is arranged on the upper opening of the metal bottom groove, and the size of the metal mesh cover is smaller than that of the upper opening of the plastic bottom groove. When working, the metal mesh cover is opened, the metal bottom groove is held with both hands, and the metal bottom groove is shaken left and right or up and down to make the bedding and feces fall into the plastic bottom groove that has been contaminated, while the mouse is still in the metal bottom groove. At this time, the metal bottom groove is inclined at about 45 degrees, the opening end of the metal bottom groove with the slope faces upwards, and the mouse slides to the lower side. The activity partition plate is installed in the partition plate clamping groove, and the activity range of the mouse is limited to the 1 / 3 area of the rear side of the metal bottom groove. At this time, the metal bottom groove with the mouse is installed into the cleaned plastic bottom groove, new bedding is poured into the area separated by the activity partition plate and evenly spread. The activity partition plate is removed, the mouse is driven to the area with the changed bedding, the whole mouse cage is lifted and slightly shaken to make the bedding uniform, and the metal mesh cover is installed to complete the process of changing the bedding of the mouse.

[0004] From the above description, it can be known that the novel experimental mouse cage has a limited activity space for the mouse inside when working, and the liveliness of the mouse within a period of time before and after injection of drugs cannot be observed. The most obvious performance of the liveliness is the sustainable movement time of the mouse. Since the activity space is in a fixed form and the space is limited, and the mouse is often in a stationary state, it is difficult to observe the liveliness of the mouse.

[0005] The placing device for facilitating mouse movement also comprises a drum-type mouse placing cage, since the mouse is stored in the drum-type space structure, when the drum body rotates, the mouse is in a state of movement due to the change of the space under the feet, so as to facilitate observation, but due to the gravity of the drum body and the mouse itself, there is a rolling friction resistance between the rotating connecting parts between the drum body and the support body, the greater the friction, the greater the driving strength required when the mouse movement makes the drum body rotate, and the activity precision of the mouse due to the resistance is limited, therefore, in order to reduce the resistance, the drum body is often designed to be small in size and light in weight, and the structure often leads to small activity space of the mouse, which also affects the activity degree of the mouse. SUMMARY

[0006] (I) Technical problems to be solved

[0007] In view of the defects of the prior art, the present application provides a placing device for analyzing mouse vital signs, which controls the friction force when the glass cage body rotates by gas pressure, the rotating tendency of the glass cage body formed by the friction force is consistent with the movement direction of the mouse, thereby offsetting the rolling friction resistance between the rotating connecting parts between the glass cage body and the support body, improving the activity degree of the mouse when observing the mouse, and solving the above technical problems.

[0008] (II) Technical solutions

[0009] In order to achieve the above-mentioned purpose, the present application provides the following technical solutions: a placing device for analyzing mouse vital signs, comprising a bottom fixed base plate, a glass cage body, a drum-shaped placing cavity arranged at the center of the glass cage body and used for placing a mouse, a gas exchange hole arranged in an annular array on the circumferential surface of the glass cage body, a movable door mounted on one end surface of the glass cage body by a movable hinge and used for placing an object inside the drum-shaped placing cavity, two horizontal rotating shafts rotatable with the glass cage body, and a support body rotatably sleeved on the shaft body of the horizontal rotating shaft and mounted on the upper end surface of the bottom fixed base plate, further comprising a first friction plate fixedly mounted on the end of one of the horizontal rotating shafts and rotatable with the glass cage body; a gas-type rotating structure mounted above the bottom fixed base plate and having a friction surface abutting against the surface of the first friction plate, the gas-type rotating structure being rotatable relative to the surface of the first friction plate by the gas pressure in the gas-type rotating structure, and the gas-type rotating structure being capable of transmitting the rotating state; a spring-type gas pressure control structure mounted in the gas-type rotating structure and capable of controlling the maximum pressure of the gas in the gas-type rotating structure by the elasticity of the spring; and a driving motor mounted above the bottom fixed base plate and capable of driving the rotation of the gas-type rotating structure.

[0010] The above technical solution utilizes gas pressure to control the frictional force between the rotating glass cages via a drive motor. This frictional force creates a rotational trend in the glass cages that aligns with the mouse's movement direction, thereby counteracting the rolling frictional resistance between the rotating connecting parts of the glass cages and the support structure. This enhances the observation of the mouse's activity level. Furthermore, the rotational friction intensity controlled by the air pressure, under the elastic control of the helical spring, possesses a constant pressure control capability. This ensures that the small resistance experienced by the mouse during movement remains constant, reducing negative external influences and improving the accuracy of the assessment of the mouse's activity level during observation.

[0011] Preferably, the glass cage is a glass roller structure with closed ends.

[0012] The above technical solution facilitates the observation of the mouse's movement.

[0013] Preferably, the volume of the roller-shaped placement cavity is sufficient to prevent the mice and their food from sliding due to gravity when the roller-shaped placement cavity is stationary.

[0014] The above technical solutions enable mice to live normally, while providing a sufficiently large space for them to move around actively.

[0015] Preferably, the rotational speed of the rotor of the drive motor is not less than the maximum rotational speed of the glass cage when the mouse is in motion.

[0016] The above technical solution enables the rotary drive to work continuously alongside the glass cage, thus ensuring that the interaction force between frictional forces remains in a working state.

[0017] The preferred gas type rotating structure comprises a cylindrical rotating body rotatably mounted in the support body mounting hole through a bearing, a gas storage cavity is arranged in the center of the cylindrical rotating body, a component movable hole is arranged on one end face of the gas storage cavity, a gas limiting flow hole is arranged on the other end face of the gas storage cavity, a gas injection hole for injecting gas into the inside of the gas limiting flow hole is arranged in the inside of the cylindrical rotating body, a gas valve for controlling the flow of gas is mounted in the inside of the gas injection hole, a component mounting hole is arranged in the inside of the cylindrical rotating body, a spring type gas pressure control structure for controlling the outward discharge of gas in the inside of the gas limiting flow hole is sealingly mounted in the inside of the component mounting hole, a main piston plate movable along the axis of the gas storage cavity is arranged in the inside of the gas storage cavity, a telescopic contact rod penetrating through the component movable hole is fixedly mounted on one end face of the main piston plate, a second friction plate capable of contacting the first friction plate is fixedly mounted on the end of the telescopic contact rod located outside, the structural radius of the gas limiting flow hole is smaller than the structural radius of the gas storage cavity, a gas sealing ring is clamped on the circumferential face of the main piston plate, the cross-sectional structural shape of the component movable hole and the cross-sectional structural shape of the telescopic contact rod are consistent, and both are polygonal structures, and the cross-sectional structural sizes of the two are the same.

[0018] Through the above technical scheme, the rolling friction resistance between the rotating connecting parts between the glass cage and the support body can be offset, the liveliness of the mouse when observing the mouse can be improved, the negative influence of the outside world can be reduced, and the judgment degree of the liveliness of the mouse when observing can be improved.

[0019] The preferred spring type gas pressure control structure comprises a hollow shell which can be seamlessly mounted in the inside of the component mounting hole, a longitudinal reciprocating cavity is arranged in the inside of the hollow shell, an exhaust hole is arranged at the bottom end of the longitudinal reciprocating cavity, a limiting groove with a smaller structural radius is arranged at the top end of the longitudinal reciprocating cavity, an air inlet hole with a smaller structural radius and connected to the gas limiting flow hole is arranged at the top end of the limiting groove, a movable plate movable along the axis is arranged in the inside of the longitudinal reciprocating cavity, a secondary piston plate which can be seamlessly inserted into the inside of the limiting groove is mounted on the upper end face of the movable plate, a plurality of air holes are arranged in the plate body between the edge of the movable plate and the edge of the secondary piston plate, a spiral spring in a compressed state is fixedly mounted at the bottom end of the movable plate, the elastic strength of the spiral spring in the initial state controls the maximum gas pressure in the gas storage cavity, and the maximum friction strength of the first friction plate and the second friction plate in contact is equivalent to the maximum rotating resistance of the glass cage when rotating.

[0020] The technical scheme has the following beneficial effects: the rolling friction resistance between the rotating connecting components between the glass cage and the support body is offset, the liveliness of the mouse when moving is improved, the rotating friction intensity controlled by the air intensity has the constant pressure control ability under the elastic control of the spiral spring, so that the slight resistance suffered by the mouse when moving is kept in a constant state, the negative influence of the external environment is reduced, and the judgment degree of the liveliness of the mouse when observing is improved.

[0021] Preferably, the bottom fixed base plate is provided with an angle positioning structure capable of controlling the rotation angle around the center line part, the angle positioning structure comprises two support base plates, a cylindrical shell is fixed on the top of the support base plate through a longitudinal support rod, an inner rotating column capable of rotating in the cylindrical shell is arranged in the center of the cylindrical shell, a fixed shaft rotating with the inner rotating column is arranged on one rotating end of the inner rotating column, one end of the fixed shaft is fixedly arranged on one side of the middle part of the bottom fixed base plate, two inner insertion grooves at an angle of 90 degrees are arranged in the middle of the circumferential side of the inner rotating column, a component movement cavity is arranged in the cylindrical shell, a secondary spiral spring in a compressed state is arranged in the component movement cavity, a pin structure capable of moving axially in the component movement cavity and capable of being inserted into one of the inner insertion grooves is arranged at the bottom end of the secondary spiral spring, the pulling end of the pin structure is arranged above the cylindrical shell, when the pin structure is inserted into one of the inner insertion grooves, the bottom fixed base plate is in a horizontal state, and when the pin structure is inserted into the other inner insertion groove, the bottom fixed base plate is in a state perpendicular to the horizontal plane.

[0022] The technical scheme has the following beneficial effects: the comfort of the mouse when moving on the plane in a non-observation state is improved, and the difference in treatment in the arrangement is realized, that is, the switchability between the working state and the non-working state.

[0023] Compared with the prior art, the arrangement device for analyzing the vital signs of the mouse has the following beneficial effects:

[0024] The arrangement device for analyzing the vital signs of the mouse has the following beneficial effects: the friction between the rotating glass cages is controlled by the gas pressure control driving motor, the rotating tendency of the glass cages formed by the friction is consistent with the moving direction of the mouse, the rolling friction resistance between the rotating connecting components between the glass cage and the support body is offset, the liveliness of the mouse when moving is improved, the rotating friction intensity controlled by the air intensity has the constant pressure control ability under the elastic control of the spiral spring, so that the slight resistance suffered by the mouse when moving is kept in a constant state, the negative influence of the external environment is reduced, and the judgment degree of the liveliness of the mouse when observing is improved. BRIEF DESCRIPTION OF DRAWINGS

[0025] Figure 1It is a full section schematic diagram of the present application;

[0026] Figure 2 It is a perspective view of the present application;

[0027] Figure 3 It is a perspective section view of the gas type rotating structure in the present application;

[0028] Figure 4 It is a perspective view of the main piston plate, the telescopic contact rod and the second friction plate in the present application;

[0029] Figure 5 It is a perspective section view of the spring type gas pressure control structure in the present application;

[0030] Figure 6 It is a perspective view of the auxiliary piston plate and the movable plate in the present application;

[0031] Figure 7 It is a full section schematic diagram of the angle positioning structure in the present application.

[0032] Wherein: 1, the bottom fixed base plate; 2, the support body; 3, the horizontal rotating shaft; 4, the glass cage; 5, the drum-shaped placement cavity; 6, the movable door; 7, the air exchange hole; 8, the first friction plate; 9, the driving motor; 10, the gas type rotating structure; 101, the cylindrical rotating body; 102, the gas storage cavity; 103, the component movable hole; 104, the gas limiting flow hole; 105, the gas injection hole; 106, the gas valve; 107, the component mounting hole; 108, the main piston plate; 109, the telescopic contact rod; 1010, the second friction plate; 11, the spring type gas pressure control structure; 111, the hollow shell; 112, the longitudinal reciprocating cavity; 113, the exhaust hole; 114, the limiting groove; 115, the air inlet hole; 116, the auxiliary piston plate; 117, the movable plate; 118, the air hole; 119, the spiral spring; 12, the angle positioning structure; 121, the support base plate; 122, the longitudinal support rod; 123, the cylindrical outer shell; 124, the inner rotating column; 125, the fixed shaft; 126, the inner insertion groove; 127, the component movement cavity; 128, the pin structure; 129, the auxiliary spiral spring. DETAILED DESCRIPTION

[0033] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0034] Please refer to Figures 1-2The application relates to a device for placing mice for analyzing their vital signs, which comprises a bottom fixed base plate 1, a glass cage 4, a drum-shaped placing cavity 5 arranged at the center of the glass cage 4 and used for placing mice, air holes 7 arranged in a ring array on the circumferential surface of the glass cage 4, a movable door 6 movably connected to one end surface of the glass cage 4 and used for placing objects into the drum-shaped placing cavity 5, two horizontal rotating shafts 3 rotatable with the glass cage 4, a support 2 rotatably sleeved on the shaft body of the horizontal rotating shaft 3 through a bearing and arranged on the upper end surface of the bottom fixed base plate 1, a first friction plate 8 fixedly arranged at the end of one of the horizontal rotating shafts 3 and rotatable with the glass cage 4, a gas type rotating structure 10 arranged above the bottom fixed base plate 1 and having a friction surface abutting against the plate surface of the first friction plate 8, the gas type rotating structure 10 being rotatable relative to the plate surface of the first friction plate 8 through the gas pressure in the gas type rotating structure 10, and the gas type rotating structure 10 being capable of transmitting the rotating state, a spring type gas pressure control structure 11 arranged in the gas type rotating structure 10 and capable of controlling the maximum pressure of the gas in the gas type rotating structure 10 through the elasticity of the spring, and a driving motor 9 arranged above the bottom fixed base plate 1 and capable of driving the gas type rotating structure 10 to rotate, the glass cage 4 being a drum body structure made of glass and having closed end surfaces, the drum body structure made of glass being capable of observing the state of the mice in the drum-shaped placing cavity 5 from multiple angles without dead angle, thus facilitating observation, the space volume of the drum-shaped placing cavity 5 being sufficient to prevent the mice and the food of the mice from sliding due to gravity when the mice and the food are placed in the drum-shaped placing cavity 5 in a static state, the space volume of the drum-shaped placing cavity 5 being sufficient to prevent the mice and the food of the mice from sliding due to gravity when the mice and the food are placed in the drum-shaped placing cavity 5 in a static state, and the rotating speed of the rotor of the driving motor 9 being not less than the maximum rotating speed of the glass cage 4 in a mouse moving state, due to the rotating speed, the driving motor 9 can drive the second friction plate 1010 to always generate driving influence on the glass cage 4 in various speed states, so that the rotating driving can always work with the glass cage 4, and thus the acting force between the friction forces can always be in a working state.

[0035] Please refer to Figures 3-4The gas type rotating structure 10 comprises a cylindrical rotating body 101 rotatably mounted in the mounting hole of the support body 2 through a bearing, a gas storage cavity 102 is arranged in the center of the cylindrical rotating body 101, a component movable hole 103 is arranged on one end surface of the gas storage cavity 102, a gas limiting flow hole 104 is arranged on the other end surface of the gas storage cavity 102, a gas injection hole 105 for injecting gas into the inside of the gas limiting flow hole 104 is arranged in the inside of the cylindrical rotating body 101, a gas valve 106 for controlling the flow of gas is mounted in the inside of the gas injection hole 105, a component mounting hole 107 is arranged in the inside of the cylindrical rotating body 101, a spring type gas pressure control structure 11 for controlling the outward discharge of gas in the inside of the gas limiting flow hole 104 is sealingly mounted in the inside of the component mounting hole 107, a main piston plate 108 which can move axially is arranged in the inside of the gas storage cavity 102, a telescopic contact rod 109 which can pass through the component movable hole 103 is fixedly mounted on one end surface of the main piston plate 108, a second friction plate 1010 which can contact the surface of the first friction plate 8 is fixedly mounted on the other end of the telescopic contact rod 109 which is located outside, the structural radius of the gas limiting flow hole 104 is smaller than that of the gas storage cavity 102, a gas sealing ring is clamped on the circumferential surface of the main piston plate 108, the cross-sectional structural shape of the component movable hole 103 and that of the telescopic contact rod 109 are consistent, both are polygonal structures, and the structural sizes of the cross sections of the two are the same, a sufficient amount of gas is injected into the inside of the gas injection hole 105 by using an air pump, a high pressure interval is formed in the communication area of the gas storage cavity 102, the high pressure gas in the high pressure interval makes the main piston plate 108 have a movement trend in the direction of the first friction plate 8, the strength of the gas pressure acting on the surface of the main piston plate 108 can be directly converted into the force of the second friction plate 1010 acting on the first friction plate 8, the force forms a pressure, which can make the second friction plate 1010 have a certain rotational friction force when rotating relative to the first friction plate 8, the friction force can guide the first friction plate 8 to make the glass cage 4 have a rotating trend, the rotating force formed by the rotating strength can offset the rolling friction resistance between the rotating connecting components between the glass cage 4 and the support body, improve the liveliness of the mouse when observing, reduce the negative influence of the outside world, and improve the judgment degree of the liveliness of the mouse when observing.

[0036] Please refer to Figures 5-6, the spring type air pressure control structure 11 comprises a hollow shell 111 which can be seamlessly installed inside the component mounting hole 107, the inside of the hollow shell 111 is provided with a longitudinal reciprocating cavity 112, the bottom end of the longitudinal reciprocating cavity 112 is provided with an exhaust hole 113, the top end of the longitudinal reciprocating cavity 112 is provided with a limiting groove 114 with a relatively small structure radius, the top end of the limiting groove 114 is provided with an air inlet hole 115 with a small structure radius and connected with the gas limiting flow hole 104, the inside of the longitudinal reciprocating cavity 112 is placed with a movable plate 117 which can move along the axial direction, the upper end surface of the movable plate 117 is installed with a secondary piston plate 116 which can be seamlessly inserted into the inside of the limiting groove 114, the plate body between the edge of the movable plate 117 and the edge of the secondary piston plate 116 is provided with a plurality of air holes 118, the bottom end of the movable plate 117 is fixedly installed with a compressed spiral spring 119, the elastic strength of the spiral spring 119 in the initial state controls the maximum air pressure in the gas storage cavity 102, and the pressure makes the maximum friction strength of the first friction plate 8 and the second friction plate 1010 in the resisting type equivalent to the maximum rotation resistance of the glass cage 4 when rotating, when the gas pressure stored in the gas storage cavity 102 is greater than the elastic strength of the spiral spring 119 in the initial state, the gas pressure makes the secondary piston plate 116 press down and the spiral spring 119 is compressed again, when the secondary piston plate 116 exits the limiting groove 114, the gas in the gas storage cavity 102 can be discharged outwardly along the gap between the plate bodies and the air holes 118 and the exhaust hole 113, when the air pressure strength in the gas storage cavity 102 is consistent with the elastic strength of the spiral spring 119 in the initial state, the secondary piston plate 116 enters the inside of the limiting groove 114, the control of the air pressure strength is realized, and since the elastic strength of the spiral spring 119 in the initial state controls the maximum air pressure in the gas storage cavity 102, and the pressure makes the maximum friction strength of the first friction plate 8 and the second friction plate 1010 in the resisting type equivalent to the maximum rotation resistance of the glass cage 4 when rotating, therefore, the driving motor 9 can always drive the second friction plate 1010 to rotate, but the glass cage 4 is always in a stationary state without external force, thereby canceling the rolling friction resistance existing between the rotation connecting components between the glass cage and the support body, improving the liveliness of the mouse when observing, and the rotation friction strength controlled by the air strength has constant pressure control ability under the elastic control of the spiral spring, so that the small resistance received by the mouse when moving remains in a constant state, reduces the negative influence of the external environment, and improves the judgment degree of the liveliness of the mouse when observing.

[0037] Please refer to Figure 7The bottom fixed base plate 1 is provided with an angle positioning structure 12 on both sides of the middle part, which can control the rotation angle around the center line part. The angle positioning structure 12 includes two support base plates 121, a cylindrical shell 123 is fixed above the support base plate 121 through a longitudinal support rod 122, an inner rotating column 124 which can rotate inside is placed in the center of the cylindrical shell 123, a fixed shaft 125 which rotates with the inner rotating column 124 is installed on one end of the inner rotating column 124, one end of the fixed shaft 125 is fixedly installed on one side of the middle part of the bottom fixed base plate 1, two inner insertion grooves 126 which are at an angle of 90 degrees are arranged in the middle of the circumferential side of the inner rotating column 124, a component movement cavity 127 is arranged in the inner rotating column 124, a secondary spiral spring 129 in a compressed state is placed in the component movement cavity 127, a pin structure 128 which can move axially in the component movement cavity 127 and can be inserted into one of the inner insertion grooves 126 is placed at the bottom end of the secondary spiral spring 129, the pulling end of the pin structure 128 is above the cylindrical shell 123, when the pin structure 128 is inserted into one of the inner insertion grooves 126, the bottom fixed base plate 1 is in a horizontal state; when the pin structure 128 is inserted into the other inner insertion groove 126, the bottom fixed base plate 1 is in a state perpendicular to the horizontal plane, when the mouse needs to be observed, the pin structure 128 is pulled upwards so that the pin structure 128 is inserted into one of the inner insertion grooves 126, at this time, the bottom fixed base plate 1 is in a horizontal state, in this state, the glass cage 4 is in a horizontal roller shape, and the mouse can be detected for liveliness; when the mouse does not need to be observed and only needs to maintain its living state, the bottom fixed base plate 1 is in a state perpendicular to the horizontal plane, at this time, the glass cage 4 is in a vertical roller shape, and the mouse can use one of the end faces of the roller-shaped placement cavity 5 as an activity base, thereby improving the comfort of the mouse when moving on the plane and realizing the difference in treatment, i.e. the switchability between working state and non-working state.

[0038] In use, open the movable door 6, place the mouse inside the roller-shaped placement cavity 5, then inject sufficient gas into the gas injection hole 105 using an air pump, close the air pump when no excess gas is discharged outward through the exhaust hole 113, start the driving motor 9 when there is no excess gas discharged outward through the exhaust hole 113, apply a preliminary rotating force to the glass cage 4 when the liveliness of the mouse needs to be observed, the rotating direction needs to be consistent with the direction of the driving motor 9 and the head of the mouse, since the roller-shaped placement cavity 5 is in a rotating state, the mouse cannot remain in a plane at this time, and therefore will run in the rotating direction, by observing the state and time when running or walking, the specific liveliness and corresponding vital signs of the mouse at this time can be obtained.

[0039] While embodiments of the application have been shown and described, it is to be understood that the embodiments described are merely exemplary of the principles and application of the present application. Numerous modifications and adaptions can be effected without departing from the spirit and scope of the present application, which is not limited to the exact construction and arrangement described. It is intended, therefore, to cover all modifications and adaptions that fall within the scope of the claims and their equivalents.

Claims

1. A device for placing mice for analysis of vital signs, comprising a bottom fixed base plate (1), a glass cage (4), a drum-shaped placing cavity (5) arranged in the center of the glass cage (4) and used for placing mice, air exchange holes (7) arranged in an annular array on the circumferential surface of the glass cage (4), a movable door (6) mounted on one end surface of the glass cage (4) through a movable hinge and used for placing objects inside the drum-shaped placing cavity (5), two horizontal rotating shafts (3) rotatable with the glass cage (4), and a support body (2) rotatably sleeved on the shaft body of the horizontal rotating shaft (3) through a bearing and mounted on the upper end surface of the bottom fixed base plate (1), characterized in that: Also included is a first friction plate (8) fixedly mounted at the end of one of the horizontal rotating shafts (3) and rotating with the glass cage (4); A gas type rotating structure (10) mounted above the bottom fixed base plate (1) and having a friction surface in contact with the surface of the first friction plate (8), the gas type rotating structure (10) being capable of rotating relative to the surface of the first friction plate (8) by the gas pressure in its interior, and the gas type rotating structure (10) being capable of transmitting the rotating state; A spring type gas pressure control structure (11) mounted in the interior of the gas type rotating structure (10) and capable of controlling the maximum pressure in the interior of the gas type rotating structure (10) by spring elasticity; And a driving motor (9) mounted above the bottom fixed base plate (1) and capable of driving the rotation of the gas type rotating structure (10); The gas type rotating structure (10) includes a cylindrical rotating body (101) rotatably mounted in the mounting hole of the support body (2) by a bearing, the center of the cylindrical rotating body (101) being provided with a gas storage cavity (102), one end surface of the gas storage cavity (102) being provided with a component movable hole (103), the other end surface of the gas storage cavity (102) being provided with a gas limiting flow hole (104), the interior of the cylindrical rotating body (101) being provided with a gas injection hole (105) for injecting gas into the interior of the gas limiting flow hole (104), the interior of the gas injection hole (105) being mounted with a gas valve (106) capable of controlling the flow of gas, the interior of the cylindrical rotating body (101) being provided with a component mounting hole (107), the interior of the component mounting hole (107) being sealingly mounted with a spring type gas pressure control structure (11) capable of controlling the outward discharge of gas from the interior of the gas limiting flow hole (104), the interior of the gas storage cavity (102) being provided with a main piston plate (108) capable of moving along the axial direction thereof, one end surface of the main piston plate (108) being fixedly mounted with an extension and contact rod (109) penetrating through the component movable hole (103), one end of the extension and contact rod (109) being fixedly mounted with a second friction plate (1010) capable of contacting the surface of the first friction plate (8).

2. The positioning device for analyzing vital signs of a mouse according to claim 1, wherein: The glass cage (4) is a glass drum body structure, and the two end surfaces are closed structures.

3. The positioning device of claim 2, wherein: The space volume of the drum-shaped placement cavity (5) is sufficient to prevent the mouse and the mouse food placed in the interior thereof from sliding due to gravity when the drum-shaped placement cavity (5) is in a stationary state.

4. The positioning device of claim 3, wherein: The rotating speed of the rotor of the driving motor (9) is not less than the maximum rotating speed of the glass cage (4) in the mouse moving state.

5. The positioning device of claim 4, wherein: The structure radius of the gas limiting flow hole (104) is less than the structure radius of the gas storage cavity (102), the circumferential surface of the main piston plate (108) is provided with a gas sealing ring, the cross-sectional structure shape of the component movable hole (103) and the cross-sectional structure shape of the extension and contact rod (109) are consistent, and both are polygonal structures, and the cross-sectional structure sizes of the two are the same.

6. The positioning device of claim 5, wherein: The spring type air pressure control structure (11) comprises a hollow shell (111) which can be seamlessly installed inside the component mounting hole (107), the inside of the hollow shell (111) is provided with a longitudinal reciprocating cavity (112), the bottom end of the longitudinal reciprocating cavity (112) is provided with an exhaust hole (113), the top end of the longitudinal reciprocating cavity (112) is provided with a limiting groove (114) with a relatively small structure radius, the top end of the limiting groove (114) is provided with an air inlet hole (115) with a small structure radius and connected with the gas limiting flow hole (104), the inside of the longitudinal reciprocating cavity (112) is placed with a movable plate (117) which can move along the axial direction, the upper end surface of the movable plate (117) is installed with a secondary piston plate (116) which can be seamlessly inserted into the inside of the limiting groove (114), a plurality of air holes (118) are arranged in the plate body between the edge of the movable plate (117) and the edge of the secondary piston plate (116), and the bottom end of the movable plate (117) is fixedly installed with a spiral spring (119) in a compressed state.

7. The positioning device of claim 6, wherein: The elastic strength of the spiral spring (119) in the initial state controls the maximum air pressure in the gas storage cavity (102), and the maximum friction strength of the first friction plate (8) and the second friction plate (1010) in the abutting mode is equivalent to the maximum rotation resistance of the glass cage (4) when rotating.

8. The positioning device for facilitating analysis of vital signs of a mouse according to any one of claims 1-7, wherein: The angle positioning structure (12) is installed on both sides of the middle part of the bottom fixed base plate (1) and can control the rotation angle around the center line part, the angle positioning structure (12) comprises two support base plates (121), a cylindrical shell (123) is fixed above the support base plate (121) through a longitudinal support rod (122), an inner rotating column (124) which can rotate inside is placed in the center of the cylindrical shell (123), a fixed shaft (125) which rotates with the inner rotating column (124) is installed on one rotating end of the inner rotating column (124), one end of the fixed shaft (125) is fixedly installed on one side of the middle part of the bottom fixed base plate (1), two inner insertion grooves (126) which are at an angle of ninety degrees are arranged in the middle of the circumferential side surface of the inner rotating column (124), a component movement cavity (127) is arranged in the inside of the cylindrical shell (123), a secondary spiral spring (129) in a compressed state is placed in the inside of the component movement cavity (127), a pin structure (128) which can move axially along the component movement cavity (127) and can be correspondingly inserted into one inner insertion groove (126) is placed at the bottom end of the secondary spiral spring (129), and the pulling end of the pin structure (128) is located above the cylindrical shell (123).

9. The positioning device of claim 8, wherein: When the pin structure (128) is inserted into one of the inner insertion grooves (126), the bottom fixed base plate (1) is in a horizontal state, and when the pin structure (128) is inserted into the other inner insertion groove (126), the bottom fixed base plate (1) is in a state perpendicular to the horizontal plane.

Images