Sample image scanning device, sample detection system, and liquid-based sample detection system

Abstract

The application discloses a sample image scanning device, a sample detection system and a liquid-based sample detection system, which comprise a transfer device, a scheduling device, a scanning device and a slide unloading device. The transfer device comprises a first track and a transfer mechanism. The first track is provided with a transfer position and a recovery position. The transfer mechanism is used for moving along the first track to transfer a first slide basket loaded with slides to the transfer position and to transfer an empty first slide basket from the transfer position to the recovery position. The scheduling device is used for transferring the slides located at the transfer position to a scanning position. The scanning device is used for scanning the slides located at the scanning position. The slide unloading device is used for containing the scanned slides. The scheduling device is further used for transferring the scanned slides to the slide unloading device. The scanned slides are stored through the slide unloading device, the waiting time of the slide basket is saved, the slide basket can be prevented from being polluted by mirror oil, the repeated use of the slide basket is facilitated, and the work efficiency is improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical equipment, and in particular to a sample image scanning device, a sample detection system and a liquid-based sample detection system. BACKGROUND

[0002] The sample image scanning device is a device for automatically examining a prepared slide. The device captures sample images on the slide through a microscope, analyzes and judges the images to obtain a detection result, and assists in diagnosing diseases. Microscopic examination is a method of observing, analyzing and judging a prepared slide under a microscope. Human excreta, secretions, exfoliated cells, human tissues, animal tissues, and even plant cells can be used as microscopic examination objects, and the method is commonly used to assist in diagnosing diseases.

[0003] Currently, during the operation of the sample image scanning device, the prepared slides are usually loaded in a slide basket and transported to a corresponding position of the sample image scanning device by a transport device for scanning. The slides need to be placed back into the slide basket where they were originally loaded after the scanning is completed for slide unloading, which results in a long waiting time of the slide basket and affects the work efficiency of the sample image scanning device. SUMMARY

[0004] Therefore, the present application provides a sample image scanning device, a sample detection system and a liquid-based sample detection system.

[0005] The first aspect of the present application provides a sample image scanning device, comprising:

[0006] A transfer device, comprising a first track and a transfer mechanism, wherein the first track is provided with a transfer position and a recovery position, and the transfer mechanism is configured to move along the first track to transfer a first slide basket loaded with slides to the transfer position and to transfer an empty first slide basket from the transfer position to the recovery position.

[0007] A scheduling device configured to transfer the slides located at the transfer position to a scanning position.

[0008] A scanning device configured to scan the slides located at the scanning position.

[0009] A slide unloading device configured to accommodate the scanned slides, and the scheduling device is further configured to transfer the scanned slides to the slide unloading device.

[0010] The second aspect of the present application provides a sample detection system, comprising a sample preparation device, a first detection device, a control device, a display device and the sample image scanning device described above, the first detection device, the sample preparation device and the sample image scanning device are electrically connected with the control device, the first detection device is used to detect the sample and output a first detection result, the sample preparation device is used to prepare a sample slide, the sample image scanning device is used to receive and scan the sample slide prepared by the sample preparation device, when the first detection result is abnormal, the control device controls the sample preparation device to prepare a sample slide and controls the sample slide to be transported to the sample image scanning device, the sample image scanning device receives and scans the sample slide and outputs a scanning result, and the display device displays the first detection result and the scanning result; wherein the sample is any one of a blood sample and a gynecological sample.

[0011] The third aspect of the present application provides a liquid-based sample detection system, comprising a sample preparation device, a control device, a display device and the sample image scanning device described above, the sample preparation device and the sample image scanning device are electrically connected with the control device, the sample preparation device is used to prepare a liquid-based sample slide, the sample image scanning device is used to receive and scan the liquid-based sample slide prepared by the sample preparation device, the control device controls the sample preparation device to prepare a liquid-based sample slide and controls the liquid-based sample slide to be transported to the sample image scanning device, the sample image scanning device receives and scans the liquid-based sample slide and outputs a scanning result, and the display device displays the scanning result.

[0012] As can be seen from the above technical solutions, the sample image scanning device of the present application moves on the first track through the transfer device to transfer the first slide basket loaded with slides to the transfer position and transfer the first slide basket with no load to the recovery position, which is compact in structure and reasonably utilizes space, the first slide basket with no load can be moved out after all the slides are taken out by the scheduling device, without waiting for all the slides to be scanned in the original position, the scanned slides are stored through the slide unloading device, the waiting time of the slide basket is saved and the slide basket can be reused, thereby improving work efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0013] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0014] Figure 1 It is the schematic view of the hidden part structure of the first embodiment of the sample image scanning device provided by the present application.

[0015] Figure 2 is a schematic view of the hidden part structure of the second embodiment of the sample image scanning device proposed in the present application.

[0016] Figure 3 is a schematic view of the hidden part structure of the second embodiment of the sample image scanning device proposed in the present application. Figure 2 is a partial enlarged schematic view of A in the second embodiment of the sample image scanning device proposed in the present application.

[0017] Figure 4 is a schematic view of the second embodiment of the sample image scanning device proposed in the present application.

[0018] Figure 5 is a schematic view of the hidden part structure of the second embodiment of the sample image scanning device proposed in the present application. Figure 4 is a partial enlarged schematic view of B in the second embodiment of the sample image scanning device proposed in the present application.

[0019] Figure 6 is a schematic view of the second embodiment of the sample image scanning device proposed in the present application.

[0020] Figure 7 is a schematic view of the first embodiment of the sample image scanning device proposed in the present application.

[0021] Figure 8 is a schematic view of the slide recognition device and the rotating mechanism proposed in the present application.

[0022] Figure 9 is a schematic view of the transfer device, the sample feeding device and the sample discharging device proposed in the present application.

[0023] Figure 10 is a partial enlarged schematic view of the transfer device proposed in the present application.

[0024] Figure 11 is a schematic view of the slide unloading device proposed in the present application.

[0025] Figure 12 is a schematic view of the dispatching device proposed in the present application.

[0026] Figure 13 is a schematic view of the buffer assembly proposed in the present application.

[0027] Figure 14 is a schematic view of the docking of the conveying assembly and the scanning platform proposed in the present application.

[0028] In the figure: 100, sample image scanning device; 10, transfer device; 11, first track; 111, transfer site; 112, recycling site; 113, pick-and-place site; 12, transfer mechanism; 121, pushing structure; 1211, first pushing part; 1212, second pushing part; 122, fourth drive module; 123, accommodating part; 1231, first accommodating groove; 1232, second accommodating groove; 20, scheduling device; 21, first transfer mechanism; 211, X-axis drive module; 212, Y-axis drive module; 213, Z-axis drive module; 214, mechanical clamping jaw; 22, second transfer mechanism; 22a, buffer site; 221, buffer assembly; 2211, first drive module; 2212, buffer seat; 222, conveying assembly; 2221, second drive module; 2222, conveying structure; 30, scanning device; 31, scanning site; 31a, first scanning site; 31b, second scanning site; 32, scanning mechanism; 33, scanning platform; 40, slide unloading device; 41, slide containing bin; 411, slot; 50, slide recognition device; 51, camera; 52, light barrier; 60, rotating mechanism; 61, rotating seat; 62, rotating motor; 70, controller; 80, sample feeding device; 81, second track; 82, first pushing mechanism; 90, sample discharging device; 91, third track; 92, second pushing mechanism; 110, shell; 110a, first space; 110b, second space; 110c, third space; 110d, fourth space; 110e, fifth space; 110f, sixth space; 1101, top plate; 1102, bottom plate; 1103, front plate; 1103a, first front plate; 1103b, second front plate; 1104, rear plate; 1105, first side plate; 1106, second side plate; 120, first partition plate; 130, second partition plate; 140, mirror oil receiving mechanism; 150, maintenance cover; 160, maintenance area; 161, maintenance opening; 170, emergency device; 171, fourth track; 172, transfer mechanism; 180, follow-up device; 181, bearing seat; 182, sixth drive module; 200, first slide basket; second slide basket 300. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are some of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.

[0030] It should also be understood that the terms used herein are for the purpose of describing particular embodiments and are not intended to limit the application. As used in the specification and the appended claims, the singular forms "a," "an" and "the" are intended to include plural forms unless the context clearly dictates otherwise.

[0031] It should be further understood that the term "and / or" used in the specification and the appended claims means one or more of the associated listed items as well as all possible combinations of the items.

[0032] A sample image scanning device is a device for automatically performing microscopic examination of a prepared slide. The device captures sample images on the slide through a microscope, analyzes and judges the images to obtain a detection result, and assists in diagnosing diseases. Microscopic examination is a shortened form of microscopic examination, which is performed on a prepared slide under a microscope. Human excretions, secretions, exfoliated cells, or human tissues, animal tissues, and even plant cells can be used as objects of microscopic examination, and the method is commonly used to assist in diagnosing diseases.

[0033] At present, during the operation of the sample image scanning device, the prepared slide is usually loaded in a slide basket and transported to the corresponding position of the sample image scanning device by a conveying device for scanning. After the scanning is completed, the slide is placed back into the slide basket for slide unloading, which results in a long waiting time of the slide basket and affects the work efficiency of the sample image scanning device.

[0034] Therefore, the embodiments of the present application provide a sample image scanning device, which stores the scanned slide through a slide unloading device, saves the waiting time of the slide basket, avoids the contamination of the slide basket by mirror oil, facilitates the reuse of the slide basket, and improves the work efficiency.

[0035] Referring to Figures 1-2As shown, the sample image scanning device 100 provided by the embodiment of the present application comprises a transfer device 10, a scheduling device 20, a scanning device 30 and a slide unloading device 40. The scanning device 30 is a microscope assembly capable of performing microscopic examination on the slides. The transfer device 10 comprises a first track 11 and a transfer mechanism 12. The first track 11 is provided with a transfer position 111 and a recovery position 112. The transfer mechanism 12 is used to move along the first track 11 to transfer the first slide basket 200 loaded with slides to the transfer position 111 and to transfer the first slide basket 200 loaded with slides from the transfer position 111 to the recovery position 112. The scheduling device 20 is used to transfer the slides located at the transfer position 111 to a scanning position 31. The scanning device 30 is used to scan the slides located at the scanning position 31. The slide unloading device 40 is used to accommodate the scanned slides. The scheduling device 20 is further used to transfer the scanned slides to the slide unloading device 40.

[0036] The sample image scanning device 100 provided by the embodiment of the present application is compact in structure and makes rational use of space. After all the slides are taken out by the scheduling device 20, the first slide basket 200 loaded with slides can be moved out, without waiting for all the slides to be scanned. The scanned slides are stored by the slide unloading device 40, thereby saving the waiting time of the slide basket and avoiding the contamination of the slide basket by the microscope oil. The slide basket can be reused conveniently, and the work efficiency is improved.

[0037] In some embodiments, as shown in Figure 1 、 Figures 12-14 The scheduling device 20 comprises a first transfer mechanism 21 and a second transfer mechanism 22. The second transfer mechanism 22 has a buffer position 22a. The first transfer mechanism 21 is used to transfer the slides located at the transfer position 111 to the buffer position 22a. The second transfer mechanism 22 is used to transfer the slides to be scanned located at the buffer position 22a to the scanning position 31 and to transfer the scanned slides to the buffer position 22a. The first transfer mechanism 21 is further used to transfer the scanned slides from the buffer position 22a to the slide unloading device 40. The projection of the moving path of the first transfer mechanism 21 in the vertical direction covers the areas where the transfer position 111, the buffer position 22a and the slide unloading device 40 are located, so that one first transfer mechanism 21 can transfer the slides between the transfer position 111, the buffer position 22a and the slide unloading device 40. In the embodiment, one first transfer mechanism 21 can be used to transfer the slides from the transfer position 111 to the buffer position 22a and to transfer the scanned slides from the buffer position 22a to the slide unloading device 40.

[0038] In some embodiments, the transfer station 111, the slide unloading device 40 and the buffer station 22a are arranged in a horizontal direction below the moving path of the first transfer mechanism 21, so as to shorten the moving path of the first transfer mechanism and facilitate miniaturization of the machine.

[0039] In some embodiments, as shown in Figure 2 and Figure 12 , the first transfer mechanism 21 comprises an X-axis driving module 211, a Y-axis driving module 212, a Z-axis driving module 213 and a mechanical gripper 214. The X-axis driving module 211 is configured to drive the mechanical gripper 214 to move in an X-axis direction, which is the left-right direction of the sample image scanning device 100. The Z-axis driving module 213 is configured to drive the mechanical gripper 214 to move in a Z-axis direction, which is the height direction of the sample image scanning device 100. The Y-axis driving module 212 is configured to drive the mechanical gripper 214 to move in a Y-axis direction, which is the front-back direction of the sample image scanning device 100. The mechanical gripper 214 is configured to clamp or release the slide, so as to transfer the slide. In this embodiment, the X-axis driving module 211, the Y-axis driving module 212 and the Z-axis driving module 213 are configured to drive the mechanical gripper 214 to move in three-dimensional space, so as to facilitate the transfer of the slide between multiple positions.

[0040] In some embodiments, the transfer station 111, the buffer station 22a and the slide unloading device 40 are arranged below the moving path of the mechanical gripper 214, so as to facilitate the transfer of the slide between the transfer station 111, the buffer station 22a and the slide unloading device 40 by the mechanical gripper 214.

[0041] For example, the X-axis driving module 211, the Y-axis driving module 212 and the Z-axis driving module 213 can adopt a driving mode of a driving member combined with a transmission structure. The driving member of the Y-axis driving module 212 is connected to the X-axis driving module 211 through the transmission structure. The driving member of the X-axis driving module 211 is connected to the Z-axis driving module 213 through the transmission structure. The driving member of the Z-axis driving module 213 is connected to the mechanical gripper 214 through the transmission structure, so as to realize the movement of the mechanical gripper 214 in the X-axis, Y-axis and Z-axis directions. The driving member of the X-axis driving module 211, the Y-axis driving module 212 and the Z-axis driving module 213 can adopt a driving motor or other devices that can provide driving force. The transmission structure can adopt any one of a belt transmission mechanism, a chain transmission mechanism, a gear and rack transmission mechanism or a screw transmission mechanism, so as to realize the movement of the mechanical gripper 214.

[0042] In some embodiments, as shown in Figures 12-14As shown, the slide has a vertical state when sample is fed and a horizontal state when scanning, the first transfer mechanism 21 is used to transfer the slide in vertical state, the second transfer mechanism 22 includes a buffer assembly 221 and a conveying assembly 222, the buffer assembly 221 includes a first driving module 2211 and a buffer seat 2212 for carrying the slide, a buffer site 22a is arranged on the buffer seat 2212, the first driving module 2211 is used to drive the buffer seat 2212 to rotate, so as to switch the slide on the buffer site 22a between the vertical state and the horizontal state, the conveying assembly 222 includes a second driving module 2221 and a conveying structure 2222 for transferring the slide, the second driving module 2221 is used to drive the conveying structure 2222 to move, so as to transfer the slide in horizontal state between the buffer site 22a and the scanning site 31. In the embodiment, the first transfer mechanism 21 is used to transfer the slide in vertical state from the intermediate site 111 to the buffer site 22a, the second driving module 2211 is used to drive the buffer seat 2212 to rotate, so as to switch the slide on the buffer site 22a from the vertical state to the horizontal state, and then the second driving module 2221 is used to drive the conveying structure 2222 to move, so as to transfer the slide in horizontal state to the scanning site 31 for scanning, after scanning, the second driving module 2221 drives the conveying structure 2222 to move the slide from the scanning site 31 to the buffer site 22a, at this time, the first driving module 2211 is used to drive the buffer seat 2212 to rotate, so as to switch the slide on the buffer site 22a from the horizontal state to the vertical state, so as to transfer the slide in vertical state to the slide unloading device 40 by the first transfer mechanism 21.

[0043] Exemplarily, the first driving module 2211 can drive the pulley to rotate in the mode of motor synchronous belt, the pulley is connected with the buffer seat 2212 through the rotating shaft, so as to drive the buffer seat 2212 to flip.

[0044] Exemplarily, the second driving module 2221 can drive the sliding block to move along the slide rail in the mode that the motor drives the sliding block through the transmission structure, so as to drive the conveying structure 2222 connected with the sliding block to move in or out of the slide. The transmission structure can adopt any one of belt transmission mechanism, chain transmission mechanism, gear and rack transmission mechanism or screw transmission mechanism, so as to drive the conveying structure 2222 to move.

[0045] As an implementation mode, the buffer assembly 221 is connected with the conveying assembly 222 to be integrated into the same device, so as to be compact in structure and facilitate miniaturization of the machine.

[0046] As another implementation mode, the buffer assembly 221 and the conveying assembly 222 are independently arranged, and the conveying assembly 222 is located between the buffer assembly 221 and the scanning site 31, so as to facilitate the transfer of the slide between the buffer site 22a and the scanning site 31.

[0047] In some embodiments, asFigure 2 and Figure 14 As shown in FIG. 12, the scanning device 30 comprises a scanning mechanism 32, a scanning platform 33 and a third driving module. The scanning mechanism 32 is configured to scan the slide located in the scanning position 31. The scanning position 31 is arranged on the scanning platform 33, and the scanning position 31 comprises a first scanning position 31a and a second scanning position 31b. The third driving module is connected to the scanning platform 33, and is configured to drive the scanning platform 33 to move so as to alternatively connect the first scanning position 31a and the second scanning position 31b with the conveying structure 2222. The third driving module is configured to drive the scanning platform 33 to move so as to connect the second scanning position 31b with the conveying structure 2222 when the scanning of the slide in the first scanning position 31a is completed, so that the conveying structure 2222 transfers the slide to be scanned located in the buffer position 22a to the second scanning position 31b. Then, the scanning platform 33 is driven to move so as to connect the first scanning position 31a with the conveying structure 2222, so that the conveying structure 2222 transfers the scanned slide to the buffer position 22a. In this embodiment, the first scanning position 31a and the second scanning position 31b are arranged, so as to avoid the interference between the removal of the scanned slide and the insertion of the slide to be scanned, and to improve the work efficiency.

[0048] As an example, the third driving module can drive the scanning platform 33 to move horizontally by driving the sliding block to move along the sliding rail through the motor and the transmission structure. It can be understood that the third driving module can comprise two groups of driving structures. Each group of driving structures comprises a motor, a transmission structure, a sliding block and a sliding rail, so as to realize the movement in two directions perpendicular to each other in the horizontal direction. The sliding rail of one group of driving structures can be arranged on the sliding block of the other group of driving structures and perpendicular to the sliding rail of the other group of driving structures. The structure is compact, the space is reasonably utilized, and the position of the scanning platform 33 can be adjusted in two spatial dimensions. The transmission structure can adopt any one of a belt transmission mechanism, a chain transmission mechanism, a gear and rack transmission mechanism or a screw transmission mechanism, so as to drive the scanning platform 33 to move.

[0049] In some embodiments, as shown in FIG. 13, the sample image scanning device 100 further comprises a slide recognition device 50. The first transfer mechanism 21 is configured to transfer the slide to the slide recognition device 50 for identity recognition and / or front and back recognition, and then transfer the slide from the slide recognition device 50 to the buffer position 22a. In this embodiment, the slide recognition device 50 can be arranged around the buffer seat 2212. The camera 51 and the light shield plate 52 are arranged on both sides of the buffer position 22a. The slide is photographed by the camera 51, so as to detect whether the slide is placed reversely and acquire the sample information on the slide. Figure 8

[0050] ​Optionally, the slide identification device 50 can also be integrally arranged after being connected with the buffer seat 2212, and the slide identification device 50 is arranged corresponding to the buffer position 22a. When the slide on the buffer position 22a is in the vertical state, the slide identification device 50 is used for identity recognition and / or front and back identification of the slide on the buffer position 22a. In the embodiment, the camera 51 and the light barrier 52 are installed on the buffer seat 2212 and are respectively located on both sides of the buffer position 22a. The slide is photographed by the camera 51 to detect whether the slide is placed reversely and to obtain the sample information on the slide.

[0051] Optionally, the slide identification device 50 can also be arranged on the scanning platform 33, and the slide identification device 50 is arranged corresponding to the scanning position 31 and is used for identity recognition and / or front and back identification of the slide located on the scanning position 31. In the embodiment, the camera 51 and the light barrier 52 are arranged on the scanning platform 33 and are respectively located on both sides of the scanning position 31. The slide is photographed by the camera 51 to detect whether the slide is placed reversely and to obtain the sample information on the slide.

[0052] In some embodiments, as shown in Figure 8 The sample image scanning device 100 further comprises a rotating mechanism 60, which is used to drive the slide to rotate so as to adjust the slide to be front-facing. In the embodiment, the rotating mechanism 60 is connected to the buffer seat 2212 and is used to drive the slide in the vertical state on the buffer seat 2212 to rotate horizontally so as to change the orientation of the slide, so that the slide is turned to the horizontal state with the front facing upward. Exemplarily, the rotating mechanism 60 comprises a rotating seat 61 and a rotating motor used to drive the rotating seat to rotate horizontally. The rotating seat has a clamping position used to accommodate the slide in the vertical state, so as to facilitate the change of the orientation of the slide.

[0053] In some embodiments, as shown in Figure 9 The transfer mechanism 12 comprises a pushing structure 121 and a fourth driving module 122. The pushing structure 121 is used to move the first slide basket 200. The fourth driving module 122 is connected to the pushing structure 121 and is used to drive the pushing structure 121 to move the first slide basket 200 along the first track 11 back and forth. In the embodiment, the pushing structure 121 is used to receive the first slide basket 200 loaded with the slides. The fourth driving module 122 is used to drive the pushing structure 121 to move the first slide basket 200 along the first track 11 to the transfer position 111, so that the first transfer mechanism 21 transfers the slides to the scanning position 31 for scanning.

[0054] Exemplarily, as shown in Figure 9As shown, the pushing structure 121 includes oppositely arranged first pushing part 1211 and second pushing part 1212, and the first pushing part 1211 and the second pushing part 1212 are arranged in the extension direction of the first track 11 to push the first slide basket 200 along the first track 11. In the embodiment, the first pushing part 1211 is used to abut against one side of the first slide basket 200 to push the first slide basket 200 to the transfer position 111, and the second pushing part 1212 is used to abut against the other side of the first slide basket 200 to push the first slide basket 200 out of the transfer position 111. The fourth driving module 122 includes a motor and a transmission assembly, the transmission assembly is connected with the pushing structure 121, and the motor is used to drive the transmission assembly to drive the pushing structure 121 to move along the first track 11, so as to facilitate the transfer of the first slide basket 200. The transmission assembly can adopt any one of a belt transmission mechanism, a chain transmission mechanism, a gear and rack transmission mechanism, or a screw transmission mechanism to drive the pushing structure 121 to move the first slide basket 200.

[0055] In some embodiments, as shown, Figure 9 The slides include conventional slides, emergency slides, and / or recheck slides. The first slide basket 200 is used to accommodate at least the conventional slides. The transfer mechanism 12 further includes an accommodating part 123 connected to the pushing structure 121 or the fourth driving module 122. The accommodating part 123 is used to accommodate the emergency slides and / or the recheck slides. The fourth driving module 122 is further used to drive the accommodating part 123 to move back and forth along the first track 11 to transfer the emergency slides and / or the recheck slides. In the embodiment, the accommodating part 123 can be arranged in parallel with the pushing structure 121 along the extension direction of the first track 11, so that one fourth driving module 122 can drive the accommodating part 123 to move synchronously with the pushing structure 121. Through the same first track 11 and the fourth driving module 122, the transfer of the conventional slides, the emergency slides, and / or the recheck slides can be realized. The structure is compact, the space is reasonably utilized, the volume is reduced, the cost is saved, and the miniaturization of the machine is facilitated.

[0056] For example, the conventional slides are sample slides detected in normal order, the emergency slides are sample slides that need to be detected preferentially, and the recheck slides are sample slides that need to be rechecked due to scanning structural abnormalities. The recheck slides have two forms, including first recheck slides and second recheck slides. Specifically, the slides that need to be taken out for manual microscopic examination or automatically examined on other equipment after scanning abnormalities are the first recheck slides. The slides that are prepared by a slide maker to coat the same sample according to the sample code of the scanning abnormalities, find the same sample, and then are sent into the sample image scanning device 100 for microscopic examination by the scanning device 30 are the second recheck slides.

[0057] In some embodiments, as shown,Figure 7 As shown, the first track 11 is further provided with a taking and placing position 113, which is used for a user to place an emergency slide or take a return slide, and the fourth driving module 122 is further used to drive the containing member 123 to move along the first track 11 between the transfer position 111 and the taking and placing position 113, so that the user can place an emergency slide or take a return slide through the taking and placing position 113. In the embodiment, the user can place an emergency slide or a second return slide through the taking and placing position 113, and can also take a first return slide through the taking and placing position 113.

[0058] In some embodiments, the controller 70 is configured to control the transfer mechanism 12 to move from the transfer position 111 to the taking and placing position 113 when an emergency push-out instruction is received, so that an emergency slide is placed into the containing member 123, and is configured to control the transfer mechanism 12 to transfer the emergency slide from the taking and placing position 113 to the transfer position 111 when an emergency push-in instruction is received, and control the scheduling device 20 to transfer the emergency slide from the transfer position 111 to the scanning position 31. In the embodiment, the above-mentioned arrangement can control the transfer mechanism 12 and the scheduling device 20 to give priority to the emergency slide when the emergency slide needs to be inserted, and the detection efficiency is high.

[0059] In some embodiments, the controller 70 is configured to control the scheduling device 20 to transfer a first return slide at a corresponding position in the sample image scanning device 100 into the containing member 123 at the transfer position 111 when a return push-out instruction is received, and control the transfer mechanism 12 to move the first return slide from the transfer position 111 to the taking and placing position 113. In the embodiment, the above-mentioned arrangement can control the scheduling device 20 and the transfer mechanism 12 to cooperate to move the first return slide to the taking and placing position 113 through the controller 70 when the slide scanning is abnormal and needs to be taken out for manual review or automatic microscopic examination on other equipment, so as to facilitate manual review or automatic microscopic examination on other equipment.

[0060] In some embodiments, the controller 70 is configured to control the transfer mechanism 12 to move from the transfer position 111 to the taking and placing position 113 when a return push-in instruction is received, so that a second return slide is placed into the containing member 123 or the first slide basket 200 through the taking and placing position 113, and then the second return slide is transferred to the transfer position 111, and control the scheduling device 20 to transfer the second return slide from the transfer position 111 to the scanning position 31. In the embodiment, the second return slide is specifically a new slide coated with the same sample according to the sample code of the scanning abnormality, and the new slide is sent into the sample image scanning device 100 to perform microscopic examination through the scanning device 30, and the controller 70 is configured to control the transfer mechanism 12 and the scheduling device 20 to cooperate to transfer the second return slide to the scanning position 31 for scanning, so as to obtain a review result of the same sample.

[0061] In some embodiments, as shown in FIG. 1A, the slide transport device 10 comprises a slide accommodation member 123, a slide transport mechanism 12, a slide scanning device 20, a slide unloading device 40, and a controller 70. Figure 10 In some embodiments, as shown in FIG. 1A, the slide accommodation member 123 comprises at least one first accommodation slot 1231 for accommodating an emergency slide and / or at least one second accommodation slot 1232 for accommodating a first follow-up slide. In this embodiment, the first accommodation slot 1231 is configured to accommodate the emergency slide, and the second accommodation slot 1232 is configured to accommodate the first follow-up slide, thereby avoiding confusion between the emergency slide and the first follow-up slide and preventing the mirror oil on the first follow-up slide from contaminating the emergency slide. Since the second follow-up slide is a newly prepared sample slide without mirror oil, it can be placed in the first accommodation slot 1231 or the first slide basket 200 and then fed by the transport mechanism 12.

[0062] In some embodiments, as shown in FIG. 1A, the slide accommodation member 123 comprises a first accommodation slot 1231 and a second accommodation slot 1232, which are arranged separately to leave a predetermined distance for the user to take and place the slides, thereby facilitating user operation. Figure 10

[0063] In some embodiments, the slide transport device 10 further comprises a controller 70 configured to control the transport mechanism 12 to move a first distance along the first track 11 to make the position of the first accommodation slot 1231 correspond to the taking and placing position 113 when receiving an emergency instruction, and / or control the transport mechanism 12 to move a second distance along the first track 11 to make the position of the second accommodation slot 1232 correspond to the taking and placing position 113 when receiving a follow-up instruction. In this embodiment, the first accommodation slot 1231 and the second accommodation slot 1232 are arranged separately along the extension direction of the first track 11, so the distance between the first accommodation slot 1231 and the taking and placing position 113 is different from the distance between the second accommodation slot 1232 and the taking and placing position 113. The transport mechanism 12 is driven by the motor, and the movement distance of the transport mechanism 12 can be controlled by the movement steps of the motor, so that the first accommodation slot 1231 or the second accommodation slot 1232 can be driven to correspond to the taking and placing position 113 according to different instructions.

[0064] In some embodiments, as shown in FIG. 1A, the slide unloading device 40 comprises a slide accommodation bin 41 having a plurality of slots 411 adapted to the slides, and the dispatching device 20 is configured to insert the scanned slides into the slots 411. In this embodiment, the slots 411 are configured to facilitate the placement of the slides. For example, the slide accommodation bin 41 can be provided with multiple rows of slots 411 arranged in order to facilitate the positioning of the slides. Figure 11 In some embodiments, as shown in FIG. 1A, the slide unloading device 40 comprises a slide accommodation bin 41 having a plurality of slots 411 adapted to the slides, and the dispatching device 20 is configured to insert the scanned slides into the slots 411. In this embodiment, the slots 411 are configured to facilitate the placement of the slides. For example, the slide accommodation bin 41 can be provided with multiple rows of slots 411 arranged in order to facilitate the positioning of the slides.​

[0065] It should be noted that the slide receiving chamber 41 is not limited to having a slot 411 for receiving slides. For example, in some embodiments, the slide receiving chamber 41 has multiple receiving positions for receiving slide baskets, and the slide transfer mechanism is used to transfer the scanned slides to the slide baskets in the receiving positions. In this embodiment, multiple empty slide baskets can be pre-placed in the receiving positions within the slide receiving chamber 41. When the slide baskets are full, the slide baskets and the scanned slides of the device are removed together, facilitating batch unloading of slides.

[0066] In some embodiments, such as Figure 2 As shown, since immersion varnish needs to be dripped onto the glass slide when the sample is scanned in the sample image scanning device 100, the sample image scanning device 100 also includes an immersion varnish receiving mechanism 140. The immersion varnish receiving mechanism 140 is located below the glass slide receiving chamber 41 and is used to receive immersion varnish dripping from the glass slide during the scanning process or during the transfer process after scanning. In this embodiment, the immersion varnish receiving mechanism 140 can be a receiving container with an open top to receive the dripping immersion varnish. The receiving container has a pull-out structure, which makes it easy to pull out from the sample image scanning device 100 to recover the immersion varnish.

[0067] For example, the cross-sectional area of ​​the opening of the receiving container is greater than or equal to the area covered by all the movements of the scanning device 30 and the scheduling device 20 in the sample image scanning device 100 to transfer the slides, so as to cover the movement of all the slides with added immersion oil and avoid contamination of the equipment by the immersion oil.

[0068] In some embodiments, such as Figure 9 As shown, the sample image scanning device 100 also includes a sample introduction device 80, which includes a second track 81 and a first pushing mechanism 82. The second track 81 is connected to the first track 11. The first pushing mechanism 82 is used to drive a first slide basket 200 loaded with slides to move along the second track 81 to transfer the first slide basket 200 to the first track 11. The second track 81 is perpendicular to the first track 11, and / or, the second track 81 is used to connect with a slide pusher, which is used to transfer the first slide basket 200 loaded with slides to the second track 81. In this embodiment, the second track 81 can be connected with the slide pusher to achieve automatic sample introduction of the first slide basket 200 loaded with slides. Of course, the second track 81 can also be independent of the slide pusher, allowing the first slide basket 200 loaded with slides to be manually placed onto the second track 81.

[0069] In some embodiments, such as Figure 9As shown, the sample image scanning device 100 further comprises a sample outlet device 90, which comprises a third track 91 and a second pushing mechanism 92, the recovery position 112 is connected with the third track 91, and the second pushing mechanism 92 is used to push the empty first slide basket 200 at the recovery position 112 to the third track 91. In this embodiment, the third track 91 is used to place the empty first slide basket 200, and the second track 81 and the third track 91 are both perpendicular to the first track 11. The second track 81 and the third track 91 are arranged in parallel on the same side of the first track 11, so that the first track 11, the second track 81 and the third track 91 form a U-shaped structure, so as to shorten the moving path of the first slide basket 200, improve the work efficiency, and compact the structure, which is beneficial to the miniaturization of the device.

[0070] Of course, the recovery position 112 can also be spliced with the recovery device of the external instrument to receive the empty first slide basket 200 by the recovery device of the external instrument, or the recovery position 112 can be used to splice with the slide pushing machine, which is used to receive the prepared slides into the empty first slide basket 200 and send the first slide basket 200 loaded with the slides into the sample image scanning device 100, so as to realize the repeated use of the slide basket.

[0071] In some embodiments, as Figures 1-7As shown, the sample image scanning device 100 further comprises a housing 110, a first partition 120 and a second partition 130, the housing 110 comprises oppositely arranged top plate 1101 and bottom plate 1102, oppositely arranged front plate 1103 and rear plate 1104, oppositely connected first side plate 1105 and second side plate 1106 between the front plate 1103 and the rear plate 1104, the front plate 1103 comprises a first front plate 1103a and a second front plate 1103b, the second front plate 1103b is located on the side of the first front plate 1103a away from the rear plate 1104; the first space 110a is formed between the first front plate 1103a and the rear plate 1104, the second space 110b is formed between the first front plate 1103a and the second front plate 1103b, the first partition 120 is arranged in the housing 110, and the first space 110a is divided into a third space 110c located above the first partition 120 and a fourth space 110d located below the first partition 120, the second partition 130 is arranged in the housing 110 and located below the first partition 120, and the fourth space 110d is divided into a fifth space 110e located above the second partition 130 and a sixth space 110f located below the second partition 130, wherein the slide unloading device 40 can move out of or into the fourth space 110d from the first front plate 1103a or the first side plate 1105 or the second side plate 1106, and the height of the slide unloading device 40 is higher than that of the transfer device 10, the transfer device 10 is used to transfer the first slide basket 200 loaded with slides to the fourth space 110d or move the first slide basket 200 unloaded out of the fourth space 110d, the scanning device 30 and the scheduling device 20 are arranged in the fourth space 110d, and the scheduling device 20 is used to transfer slides in the fourth space 110d to transfer slides to be scanned to the scanning position 31 or move the scanned slides out of the scanning position 31. In this embodiment, the first space 110a on the rear side of the housing 110 is divided into the third space 110c, the fifth space 110e and the sixth space 110f arranged in order from top to bottom, which is vertically arranged to reduce the horizontal size, thereby reducing the floor area occupied by the device, improving the space utilization rate, and arranging the first space 110a on the adjacent side of the second space 110b, which is beneficial to the taking and placing of slides, and at the same time, the height of the slide unloading device 40 is higher than that of the transfer device 10, avoiding the interference between the sample feeding and the slide unloading, and facilitating the user operation.

[0072] The transfer device 10 is located in the second space 110b and partially extends to the sixth space 110f, the part of the transfer device 10 extending to the sixth space 110f is a transfer position 111, and the transfer position 111 and the scanning position 31 are both located in the sixth space 110f. The scheduling device 20 is arranged in the fifth space 110e and extends to the sixth space 110f. The slide unloading device 40 can move out of or into the sixth space 110f from the first front plate 1103a or the first side plate 1105 or the second side plate 1106, so as to facilitate the scheduling device 20 to transfer the slides between the transfer position 111, the scanning position 31 and the slide unloading device 40. The scanning device 30 is arranged in the fifth space 110e and extends to the sixth space 110f, so as to facilitate scanning of the slides in the scanning position 31 of the sixth space 110f. Arranging the transfer position 111, the scanning position 31 and the slide unloading device 40 in the same area facilitates smooth transfer of the slides and improves the transfer efficiency of the slides.

[0073] In some embodiments, as shown in Figure 6 The sample image scanning device 100 further comprises a housing 110 and an inspection cover, the housing 110 has an inspection area inside, one side of the housing 110 has an inspection opening, the inspection opening is communicated with the inspection area, and the inspection cover is used to close or open the inspection opening. When the inspection cover is opened, at least one of the scanning device 30 and the scheduling device 20 is partially or entirely located in the visible range through the inspection opening. In this embodiment, the inspection opening can be opened through the inspection cover to expose the inspection area. The inspection personnel can operate and maintain the scanning device 30, the scheduling device 20 and the like in the inspection area through the inspection opening. In this application, in the case of failure of the scanning device 30, the scanning device 30 can be repaired through the inspection opening, the time for disassembling the machine body is reduced, maintenance is convenient, and the effective operation of the whole machine is ensured.

[0074] It should be noted that the sample feeding mode of the emergency slide is not limited to arranging the accommodating part 123 on the transfer mechanism 12. For example, in other embodiments, as shown in Figure 2 and Figure 4 The sample image scanning device 100 further comprises an independently arranged emergency device 170, which comprises a fourth track 171 and a transfer mechanism 172. The transfer mechanism 172 comprises a carrying structure and a fifth driving module. The carrying structure is used to place the second slide basket 300 loaded with the emergency slides. The fifth driving module is used to drive the carrying mechanism to move on the fourth track, so as to move the second slide basket 300 loaded with the emergency slides into the waiting position of the sample image scanning device 100. The scheduling device 20 is further used to transfer the slides in the second slide basket 300 located in the waiting position to the scanning position 31. In this embodiment, the emergency device 170 is independently arranged with the transfer device 10. When the emergency slide needs to be inserted, the emergency device 170 is used for processing, without waiting for the transfer mechanism 12 to enter the emergency mode from the normal mode, which is convenient for user operation.

[0075] Exemplarily, the fifth driving module comprises a motor and a transmission assembly, the transmission assembly is connected with the bearing structure, and the motor is configured to drive the transmission assembly to drive the bearing structure to move along the fourth track 171, so as to transfer the second slide basket 300 loaded with the emergency slide. The transmission assembly can adopt any one of a belt transmission mechanism, a chain transmission mechanism, a gear and rack transmission mechanism, or a screw rod transmission mechanism to realize driving the bearing structure to move.

[0076] In some embodiments, the sample image scanning device 100 further comprises a controller 70, which is configured to control the fifth driving module to drive the bearing structure to move to the loading position for loading the second slide basket 300 loaded with the emergency slide when the emergency command is received, and to control the fifth driving module to move from the loading position to the waiting position when it is detected that the second slide basket 300 is loaded on the bearing structure, and then to control the dispatching device 20 to transfer the slide in the second slide basket 300 at the waiting position to the scanning position 31. In this embodiment, when the emergency slide needs to be inserted, the controller 70 can be used to control the emergency device 170 and the dispatching device 20 to give priority to the emergency slide, so that the detection efficiency is high.

[0077] It should be noted that the feeding and removing modes of the review slide are not limited to the setting of the accommodating member 123 on the transfer mechanism 12. For example, in another embodiment, as shown in FIGS. 17 and 18, the sample image scanning device 100 further comprises a review device 180 independently arranged, which comprises a bearing seat 181 and a sixth driving module 182. The bearing seat 181 is configured to place the review slide which needs to be reviewed. The dispatching device 20 is further configured to transfer the first review slide which needs to be taken out for manual review to the bearing seat 181 or to transfer the second review slide which needs to be sent to the scanning position 31 for scanning from the bearing seat 181 to the scanning position 31. The sixth driving module 182 is configured to drive the bearing seat 181 to move, so as to remove the first review slide from the sample image scanning device 100 or to move the second review slide into the sample image scanning device 100. Figure 3 and Figure 5 In this embodiment, the review device 180 and the transfer device 10 are independently arranged, and when the first review slide needs to be taken out or the second review slide needs to be sent in, the bearing seat 181 can be driven to move by the sixth driving module 182, without waiting for the transfer mechanism 12 to enter the review mode from the normal mode, so that the operation is facilitated.

[0078] The sixth driving module 182 is configured to drive the carrier seat 181 to rotate, so that the carrier seat 181 is at least partially exposed to the sample image scanning device 100, and the user can take out the first review slide from the carrier seat 181 or put the second review slide into the carrier seat 181. In this embodiment, the carrier seat 181 is rotated to move out of or into the sample image scanning device 100, which reduces the moving stroke, is high in work efficiency, small in size, saves space, and is beneficial to miniaturization of the machine. For example, the sixth driving module 182 can drive the pulley to rotate in the mode of the motor synchronous belt, the pulley is connected to the carrier seat 181 through the rotating shaft, and the carrier seat 181 is driven to rotate.

[0079] In some embodiments, the sample image scanning device 100 further comprises a controller 70, which is configured to control the scheduling device 20 to transfer the first review slide at the corresponding position in the slide unloading device 40 into the carrier seat 181 when a review push-out command is received, and control the sixth driving module 182 to drive the carrier seat 181 to move, so that the first review slide is moved out of the sample image scanning device 100, and / or the controller 70 is configured to control the sixth driving module 182 to drive the carrier seat 181 to move to be exposed to the sample image scanning device 100 when a review push-in command is received, so that the user can put the second review slide into the carrier seat 181, and control the carrier seat 181 to move when it is detected that the second review slide is put into the carrier seat 181, so that the second review slide is moved into the sample image scanning device 100, and control the scheduling device 20 to transfer the second review slide from the carrier seat 181 to the scanning position 31. In this embodiment, the controller 70 can control the review device and the scheduling device 20 to preferentially process the review slide when the first review slide needs to be taken out or the second review slide needs to be fed, and the detection efficiency is high.

[0080] In some embodiments, the controller 70 is in communication connection with the sample feeding device 80, the transfer device 10, the scheduling device 20 and the scanning device 30, and the controller 70 is configured to detect whether the buffer position 22a is empty, control the first transfer mechanism 21 to pick up the slide from the first slide basket 200 and transfer the slide to the buffer position 22a when the buffer position 22a is empty, and control the second transfer mechanism 22 to transfer the slide to the scanning device 30 to obtain a scanning result.

[0081] In some embodiments, the slides include normal slides and abnormal slides, the first slide basket 200 is used to load at least the normal slides, the abnormal slides include review slides and / or emergency slides, the sample image scanning device 100 further comprises a review device and / or an emergency device, the review device is used to feed the review slides, the emergency device is used to feed a second slide basket 300 loaded with the emergency slides, or the transfer device 10 is used to feed the emergency slides.

[0082] The controller 70 is further configured to: when detecting that the first transfer mechanism 21 feeds the first slide basket 200, detect whether the buffer position 22a is empty, and when the buffer position 22a is empty, control the first transfer mechanism 21 to transfer the regular slide from the first slide basket 200 to the buffer position 22a; when detecting that the referral device 180 feeds the referral slide, detect whether the buffer position 22a is empty, and when the buffer position 22a is empty, control the first transfer mechanism 21 to transfer the referral slide from the referral device 180 to the buffer position 22a; when detecting that the emergency device 170 feeds the second slide basket 300 loaded with the emergency slide or the transfer device 10 feeds the emergency slide, detect whether the buffer position 22a is empty, and when the buffer position 22a is empty, control the first transfer mechanism 21 to transfer the emergency slide to the buffer position 22a; wherein the priority of the first transfer mechanism 21 to transfer the emergency slide is higher than the priority of the first transfer mechanism 21 to transfer the referral slide, and the priority of the first transfer mechanism 21 to transfer the referral slide is higher than the priority of the first transfer mechanism 21 to transfer the regular slide.

[0083] Specifically, the controller 70 is configured to control the transfer device 10, the dispatch device 20 and the scanning device 30 to jointly or independently execute a plurality of working states, and dynamically detect whether the resources of the transfer device 10, the dispatch device 20 and the scanning device 30 related to the working state can be acquired during the execution of any working state, if yes, acquire the resources related to the working state to continue to execute the working state, if no, the controller 70 controls to execute other working states.

[0084] In some embodiments, the plurality of working states at least include a first working state in which the second transfer mechanism 22 puts the slide into the first scanning position 31a or the second scanning position 31b, and a second working state in which the second transfer mechanism 22 takes out the slide from the first scanning position 31a or the second scanning position 31b.

[0085] It should be understood that when a control unit of the controller 70 acquires the resource of any device and controls the device, the device cannot be occupied by other control units and controlled by other control units, and other control units will detect that the resource of the device cannot be acquired, so other control units cannot intervene in the control of the device. Only when the controller 70 occupying the resource of the device releases the resource of the device, other control units can detect that the resource of the device can be acquired, and occupy the resource to control.

[0086] Based on this, the sample image scanning device 100 provided by the embodiments of the present application is controlled to execute different working states by multiple control units, and any control unit avoids the conflict between different working states in time sequence when multiple working states of the sample image scanning device 100 are in parallel by detecting whether the device resource can be occupied before controlling the corresponding device, and occupying the resource under the condition that the resource can be occupied to avoid the control of the device by other control units. The work of putting the slide into the first scanning position 31a or the second scanning position 31b, taking the slide out of the first scanning position 31a or the second scanning position 31b, transferring the slide, recycling the slide, and performing microscopic scanning on the slide of the sample image scanning device 100 is independently and orderly performed.

[0087] Further, the controller 70 dynamically detects whether the device resource related to the working state can be acquired during the execution of any working state, and if not, the controller 70 is controlled to execute other working states. Similarly, the controller 70 also dynamically detects whether the device resource related to the other working state can be acquired when it is controlled to execute other working states, and if so, the resource related to the working state is acquired to continue to execute the working state.

[0088] It is known that the sample image scanning device 100 can timely control the idle other devices to perform related work by the above-mentioned controller 70 logic, fully utilize each device in the sample image scanning device 100, and efficiently complete the processing of batch slide transfer, microscopic scanning, recycling and the like.

[0089] In some embodiments, the controller 70 controls to execute the first working state, which includes:

[0090] Detecting whether the resources of the scanning device 30 and the second transfer mechanism 22 can be acquired, if so, acquiring the resources of the scanning device 30 and the second transfer mechanism 22, and detecting the state of the second transfer mechanism 22;

[0091] If the second transfer mechanism 22 is in a standby feeding state of feeding the slide accommodated in the buffer position 22a to the first scanning position 31a or the second scanning position 31b, the state of the first scanning position 31a or the second scanning position 31b is detected;

[0092] If the first scanning position 31a or the second scanning position 31b is in an empty state, the second transfer mechanism 22 is controlled to cooperate with the scanning device 30 to feed the slide to the corresponding scanning position;

[0093] After the slide is fed to the corresponding scanning position, the second transfer mechanism 22 is set to an empty state, and the corresponding scanning position is set to a standby scanning state;

[0094] The resources of the scanning device 30 and the second transfer mechanism 22 are released.

[0095] For example, the control executing the first working state is specifically controlled by a thread of the first control unit of the controller 70.

[0096] When the controller 70 controls the execution of the first working state, it specifically detects whether the resources of the scanning device 30 and the second transfer mechanism 22 can be acquired, acquires the resources of the scanning device 30 and the second transfer mechanism 22 if the resources can be acquired, and then detects the state of the second transfer mechanism 22. If the second transfer mechanism 22 is currently in the standby feeding state, the state of the first scanning site 31a or the second scanning site 31b is detected. It should be understood that the standby feeding state is used to represent that the buffer site 22a contains a slide, and the slide contained in the buffer site 22a is waiting to be fed to the first scanning site 31a or the second scanning site 31b for microscopic scanning.

[0097] After detecting the state of one of the first scanning site 31a and the second scanning site 31b, if it is detected that the first scanning site 31a or the second scanning site 31b is in the empty state, the controller 70 controls the second transfer mechanism 22 to cooperate with the scanning device 30 to feed the slide to the corresponding scanning site, and after feeding the slide to the corresponding scanning site, sets the second transfer mechanism 22 to the empty state, sets the corresponding scanning site to the standby scanning state, and then releases the resources of the scanning device 30 and the second transfer mechanism 22 to release the occupation of the scanning device 30 and the second transfer mechanism 22.

[0098] It should be noted that the corresponding scanning site is one of the first scanning site 31a and the second scanning site 31b, and when it is determined that one of them is in the standby slide taking state, it can be determined that the scanning site is the corresponding scanning site.

[0099] In some embodiments, the controller 70 controls the execution of the second working state, which includes:

[0100] detecting whether the resources of the scanning device 30 and the second transfer mechanism 22 can be acquired, acquiring the resources of the scanning device 30 and the second transfer mechanism 22 if the resources can be acquired, and detecting the states of the second transfer mechanism 22, the first scanning site 31a, and the second scanning site 31b;

[0101] when it is detected that the second transfer mechanism 22 is in the empty state, and at least one of the first scanning site 31a and the second scanning site 31b is in the standby slide taking state, determining the state of the corresponding scanning site and the slide located in the corresponding scanning site, wherein the state of the slide includes one of the standby recycling state and the standby rotating state;

[0102] controlling at least the second transfer mechanism 22 to cooperate with the scanning device 30 to transfer the slide to the second transfer mechanism 22, and setting the corresponding scanning site to the empty state;

[0103] According to the state to be recycled, the second transfer mechanism 22 is set to the recycling indication state, or according to the state to be rotated, the second transfer mechanism 22 is set to the rotating indication state.

[0104] The resources of the second transfer mechanism 22 and the scanning device 30 are released.

[0105] For example, the control executing the second working state is specifically controlled by the thread of the first control unit of the controller 70.

[0106] Specifically, when the controller 70 controls the second working state, it first detects whether the resources of the scanning device 30 and the second transfer mechanism 22 can be acquired, and if so, acquires the resources of the scanning device 30 and the second transfer mechanism 22, and detects the states of the second transfer mechanism 22, the first scanning site 31a and the second scanning site 31b. When it is detected that the second transfer mechanism 22 is in the idle state, and at least one of the first scanning site 31a and the second scanning site 31b is in the state of waiting for a slide, the controller 70 determines the corresponding scanning site and the state of the slide located in the corresponding scanning site.

[0107] It should be noted that the corresponding scanning site is one of the first scanning site 31a and the second scanning site 31b, and when it is determined that one of them is in the state of waiting for a slide, the scanning site is determined as the corresponding scanning site.

[0108] It should be further noted that the way the controller 70 determines the state of the slide can be to directly read the state set by the controller 70 for the slide, and the state of the slide specifically includes one of the state to be recycled and the state to be rotated. The slide in the state to be recycled indicates that the sample image scanning device 100 has performed a microscopic scanning operation on the slide, and the slide is to be recycled; the slide in the state to be rotated indicates that the attitude of the slide is abnormal, and the slide is to be rotated.

[0109] After determining the state of the slide located in the scanning site, the controller 70 at least controls the second transfer mechanism 22 and the scanning device 30 to cooperate to transfer the slide to the buffer site 22a of the second transfer mechanism 22, and sets the corresponding scanning site to the idle state. Then, according to the state of the slide located in the corresponding scanning site, the state of the second transfer mechanism 22 is set, and the resources of the second transfer mechanism 22 and the scanning device 30 are released. Among them, the controller 70 can set the state of the second transfer mechanism 22 to the recycling indication state or the rotating indication state, and at the same time release the idle state of the second transfer mechanism 22.

[0110] Specifically, if the slide is in a to-be-recovered state, the controller 70 sets the second transfer mechanism 22 to a recovery indication state; if the slide is in a to-be-rotated state, the controller 70 sets the second transfer mechanism 22 to a rotation indication state. The recovery indication state and the rotation indication state are respectively used to indicate that the controller 70 controls the slide to be recovered and rotated.

[0111] The controller 70 proposed in the embodiments of the present application can be a PLC (Programmable Logic Controller) 70, a DDC (Direct Digital Controller) 70, or a single-chip microcomputer control system, etc., to realize the above control process.

[0112] The embodiments of the present application also provide a sample detection system, which comprises a slide preparation device, a first detection device, a control device, a display device, and the sample image scanning device 100. The first detection device, the slide preparation device, and the sample image scanning device 100 are electrically connected to the control device. The first detection device is used to detect a sample and output a first detection result. The slide preparation device is used to prepare a sample slide. The sample image scanning device 100 is used to receive and scan the sample slide prepared by the slide preparation device. When the first detection result is abnormal, the control device controls the slide preparation device to prepare a sample slide and controls the sample slide to be transported to the sample image scanning device 100. The sample image scanning device receives and scans the sample slide and outputs a scanning result. The display device displays the first detection result and the scanning result. The sample is any one of a blood sample and a gynecological sample. The sample detection system proposed in the embodiments of the present application has all the beneficial effects brought by the technical solutions of any one of the embodiments of the sample image scanning device 100, which will not be repeated here.

[0113] For example, when the sample is a blood sample, the first detection device is a blood cell analysis device, such as a blood routine and specific protein detection all-in-one machine, a blood routine detector, or a specific protein detector, etc. When the sample is a gynecological sample, the first detection device is at least one of a dry chemical detection device, a dry chemical detection device, a dry staining and microscopic examination all-in-one machine, and a dry staining and microscopic examination device. When the sample is a blood sample or a gynecological sample, the slide preparation device is a slide pushing module, a staining module, or a slide pushing and staining all-in-one module.

[0114] The embodiment of the present application further provides a liquid-based sample detection system, comprising a sample slide preparation device, a control device, a display device and the sample image scanning device 100, the sample slide preparation device and the sample image scanning device 100 are electrically connected with the control device, the sample slide preparation device is used for preparing a liquid-based sample slide, the sample image scanning device 100 is used for receiving and scanning the liquid-based sample slide prepared by the sample slide preparation device, the control device controls the sample slide preparation device to prepare the liquid-based sample slide and controls the liquid-based sample slide to be transported to the sample image scanning device 100, the sample image scanning device 100 receives and scans the liquid-based sample slide and outputs a scanning result, and the display device displays the scanning result. In the embodiment, when the sample is a cervical sample, the sample detection system can be free of a first detection device, and the sample slide preparation device can include a staining module or not include the staining module. The liquid-based sample detection system provided by the embodiment of the present application has all the beneficial effects brought by the technical solutions of any one of the embodiments of the sample image scanning device 100, and details are not described herein.

[0115] The above merely describes the specific embodiments of the present application, but the protection scope of the present application is not limited to this. Any person skilled in the art can easily think of various equivalent modifications or replacements within the technical range disclosed by the present application, and these modifications or replacements should be covered in the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A sample image scanning apparatus, characterized by comprising: The application relates to a slide conveying system, comprising: a conveying device, comprising a first track and a conveying mechanism, wherein a transfer position and a recovery position are arranged on the first track, and the conveying mechanism is used for moving along the first track to convey a first slide basket loaded with slides to the transfer position and to convey the first slide basket unloaded with slides from the transfer position to the recovery position; a scheduling device, used for transferring slides located at the transfer position to a scanning position; a scanning device, used for scanning slides located at the scanning position; a slide unloading device, used for accommodating slides after scanning, and the scheduling device is further used for transferring the slides after scanning to the slide unloading device; the scheduling device comprises a first transferring mechanism and a second transferring mechanism, the second transferring mechanism has a buffer position, the slides have a vertical state at a sampling time and a horizontal state at a scanning time, and the first transferring mechanism is used for transferring the slides in the vertical state; the first transferring mechanism is used for transferring the slides located at the transfer position to the buffer position; the second transferring mechanism is used for transferring the slides to be scanned located at the buffer position to the scanning position and transferring the slides after scanning to the buffer position, and the first transferring mechanism is further used for transferring the slides after scanning from the buffer position to the slide unloading device; wherein a projection of a moving path of the first transferring mechanism in a vertical direction covers regions where the transfer position, the buffer position and the slide unloading device are located, so that one first transferring mechanism can transfer the slides between the transfer position, the buffer position and the slide unloading device; the second transferring mechanism comprises: a buffer assembly, comprising a first driving module and a buffer seat used for carrying slides, the buffer position is arranged on the buffer seat, and the first driving module is used for driving the buffer seat to rotate to switch the slides located at the buffer position between the vertical state and the horizontal state; a conveying assembly, comprising a second driving module and a conveying structure used for transferring slides, and the second driving module is used for driving the conveying structure to move to transfer the slides in the horizontal state between the buffer position and the scanning position.

2. The sample image scanning apparatus of claim 1, wherein The transfer position, the slide unloading device and the buffer position are arranged below the moving path of the first transferring mechanism in a horizontal direction.

3. The sample image scanning apparatus of claim 1, wherein the scanning device comprises: a scanning mechanism, used for scanning the slides located at the scanning position; a scanning platform, wherein the scanning position is arranged on the scanning platform, and the scanning position comprises a first scanning position and a second scanning position; a third driving module, connected to the scanning platform, and the third driving module is used for driving the scanning platform to move to make the first scanning position and the second scanning position alternately dock with the conveying structure; The third driving module is configured to drive the scanning platform to move to the second scanning position to be docked with the conveying structure when the slide scanning on the first scanning position is completed, so that the conveying structure transfers the slide to be scanned located on the buffer position to the second scanning position, and then drives the scanning platform to move to the first scanning position to be docked with the conveying structure, so that the conveying structure transfers the scanned slide to the buffer position.

4. The sample image scanning apparatus of claim 1, wherein The sample image scanning device further comprises a slide identification device, and the first transfer mechanism is configured to transfer the slide to the slide identification device for identity recognition and / or front-back face recognition, and then transfer the slide from the slide identification device to the buffer position. Alternatively, The sample image scanning device further comprises a slide identification device, and the slide identification device is arranged correspondingly to the buffer position and is configured to perform identity recognition and / or front-back face recognition on the slide on the buffer position when the slide on the buffer position is in the vertical state. The sample image scanning device further comprises a slide identification device, and the slide identification device is arranged correspondingly to the scanning position and is configured to perform identity recognition and / or front-back face recognition on the slide on the scanning position.

5. The sample image scanning apparatus of claim 4, wherein The sample image scanning device further comprises a rotating mechanism configured to drive the slide to rotate to adjust the slide to be front face.

6. The sample image scanning apparatus of claim 1, wherein, The transfer mechanism comprises: a pushing structure configured to transfer the first slide basket; a fourth driving module connected to the pushing structure, and the fourth driving module is configured to drive the pushing structure to move the first slide basket back and forth along the first track.

7. The sample image scanning apparatus of claim 6, wherein The slide comprises a regular slide, and the first slide basket is configured to accommodate at least the regular slide, and the slide further comprises an emergency slide and / or a recheck slide; The transfer mechanism further comprises an accommodating member connected to the pushing structure or the fourth driving module, and the accommodating member is configured to accommodate the emergency slide and / or the recheck slide, and the fourth driving module is further configured to drive the accommodating member to move back and forth along the first track to transfer the emergency slide and / or the recheck slide.

8. The sample image scanning apparatus of claim 7, wherein, The first track is further provided with a taking and placing position for a user to place the emergency slide or take and place the recheck slide, and the fourth driving module is further configured to drive the accommodating member to move along the first track between the transit position and the taking and placing position, so that the user places the emergency slide or takes and places the recheck slide through the taking and placing position.

9. The sample image scanning apparatus of claim 8, wherein, The recheck slide comprises a first recheck slide and a second recheck slide, and the sample image scanning device further comprises a controller; The controller is configured to control the transfer mechanism to move from the transit position to the taking and placing position to place the emergency slide into the accommodating member when receiving an emergency pushing-out instruction, and control the transfer mechanism to transfer the emergency slide from the taking and placing position to the transit position and control the scheduling device to transfer the emergency slide from the transit position to the scanning position when receiving an emergency pushing-in instruction; and / or, The controller is configured to control the scheduling device to transfer a first review slide at a corresponding position in the sample image scanning device to the accommodation member at the transit position and control the transfer mechanism to transfer the first review slide from the transit position to the pick-up position when a review push-out command is received; and / or, The controller is configured to control the transfer mechanism to move from the transit position to the pick-up position when a review push-in command is received, so that a second review slide is transferred to the transit position after the second review slide is placed into the accommodation member or the first slide basket through the pick-up position, and control the scheduling device to transfer the second review slide from the transit position to the scanning position.

10. The sample image scanning apparatus of claim 1, wherein, The slide unloading device comprises a slide accommodation bin having a plurality of slots adapted to the slides, and the scheduling device is configured to insert the scanned slides into the slots; or, The slide accommodation bin has a plurality of accommodation positions for accommodating slide baskets, and the slide transfer mechanism is configured to transfer the scanned slides into the slide baskets at the accommodation positions.

11. The sample image scanning apparatus of claim 1, wherein, The sample image scanning device further comprises a sample feeding device, which comprises a second track connected to the first track and a first pushing mechanism configured to drive the first slide basket loaded with slides to move along the second track to transfer the first slide basket to the first track, wherein the second track is arranged perpendicularly to the first track, and / or the second track is configured to be spliced with a slide pushing machine configured to move the first slide basket loaded with slides to the second track; and / or, The sample image scanning device further comprises a sample discharging device, which comprises a third track connected to the first track and a second pushing mechanism configured to push the first slide basket at the recovery position to the third track, or the recovery position is configured to be spliced with a recovery device configured to receive the first slide basket, or the recovery position is configured to be spliced with a slide pushing machine configured to transfer prepared slides to the first slide basket and move the first slide basket loaded with the slides into the sample image scanning device; and / or, The sample image scanning device further comprises a sample discharging device, which comprises a third track connected to the first track and a second pushing mechanism configured to push the first slide basket at the recovery position to the third track, or the recovery position is configured to be spliced with a recovery device configured to receive the first slide basket, or the recovery position is configured to be spliced with a slide pushing machine configured to transfer prepared slides to the first slide basket and move the first slide basket loaded with the slides into the sample image scanning device; and / or, The sample image scanning device further comprises a housing, a first partition plate and a second partition plate, the housing comprises oppositely arranged top plate and bottom plate, oppositely arranged front plate and rear plate, first side plate and second side plate connected between the front plate and the rear plate, the front plate comprises a first front plate and a second front plate, the second front plate is located on the side of the first front plate away from the rear plate; the first space is formed between the first front plate and the rear plate, the second space is formed between the first front plate and the second front plate, the first partition plate is arranged in the housing, and the first space is divided into a third space above the first partition plate and a fourth space below the first partition plate, the second partition plate is arranged in the housing and below the first partition plate, and the fourth space is divided into a fifth space above the second partition plate and a sixth space below the second partition plate, wherein the slide unloading device can move out of or into the fourth space from the first front plate or the first side plate or the second side plate, and the height of the slide unloading device is higher than that of the transfer device, the transfer device is used to transfer the first slide basket loaded with slides to the fourth space or move the first slide basket without load out of the fourth space, the scanning device and the scheduling device are arranged in the fourth space, and the scheduling device is used to transfer the slides in the fourth space to the scanning position or move the scanned slides out of the scanning position; and / or, The sample image scanning device further comprises a housing and a maintenance cover, the housing has a maintenance area, one side of the housing has a maintenance opening, the maintenance opening is communicated with the maintenance area, and the maintenance cover is used to close or open the maintenance opening. When the maintenance cover is opened, at least one of the scanning device and the scheduling device is partially or entirely located in the visible range through the maintenance opening.

12. The sample image scanning apparatus of claim 1, wherein, The slide comprises a conventional slide and an emergency slide, and the first slide basket is used to accommodate the conventional slide; The sample image scanning device further comprises: An emergency device comprising a fourth track and a transfer mechanism, the transfer mechanism comprising a bearing structure and a fifth drive module, the bearing structure being used to place a second slide basket loaded with emergency slides, and the fifth drive module being used to drive the bearing structure to move on the fourth track to move the second slide basket loaded with emergency slides into a waiting position of the sample image scanning device, and the scheduling device is further used to transfer the slides in the second slide basket located in the waiting position to the scanning position.

13. The sample image scanning apparatus of claim 12, wherein, Further comprising: A controller, the controller being used to control the fifth drive module to drive the bearing structure to move to a placing position of the bearing structure for placing the second slide basket loaded with emergency slides when an emergency command is received, and being used to control the fifth drive module to move from the placing position to the waiting position when it is detected that the second slide basket is placed on the bearing structure, and then control the scheduling device to transfer the slides in the second slide basket located in the waiting position to the scanning position.

14. The sample image scanning apparatus of claim 1, wherein, The slides include regular slides and review slides, the first slide basket is used to accommodate the regular slides, the review slides include first review slides which need to be taken out of the sample image scanning device for review and / or second review slides which need to be sent to the scanning position for scanning; The sample image scanning device further comprises: a review device comprising a carrier seat and a sixth driving module, the carrier seat is used to place the review slides, the scheduling device is further used to transfer the first review slide to the carrier seat or transfer the second review slide from the carrier seat to the scanning position, and the sixth driving module is used to drive the carrier seat to move so as to move the first review slide out of the sample image scanning device or move the second review slide into the sample image scanning device.

15. The sample image scanning apparatus of claim 14, wherein, The sixth driving module is used to drive the carrier seat to rotate so that the carrier seat is at least partially exposed outside the sample image scanning device, so that a user takes out the first review slide on the carrier seat or sends the second review slide into the carrier seat.

16. The sample image scanning apparatus of claim 14, wherein, Further comprising: a controller, when receiving a review push-out command, the controller controls the scheduling device to transfer the first review slide at a corresponding position in the slide unloading device to the carrier seat, and controls the sixth driving module to drive the carrier seat to move so as to move the first review slide out of the sample image scanning device, and / or, when receiving a review push-in command, the controller controls the sixth driving module to drive the carrier seat to move to be exposed outside the sample image scanning device, so that a user puts the second review slide into the carrier seat, and controls the carrier seat to move when detecting that the second review slide is put into the carrier seat, so as to move the second review slide into the sample image scanning device, and controls the scheduling device to transfer the second review slide from the carrier seat to the scanning position.

17. The sample image scanning apparatus of claim 1, wherein, Further comprising: a sample feeding device used to feed the first slide basket loaded with slides; a controller in communication connection with the sample feeding device, the transfer device, the scheduling device and the scanning device, the controller is used to: detect whether the buffer position is empty; when the buffer position is empty, control the first transfer mechanism to pick up the slide from the first slide basket and transfer the slide to the buffer position; control the second transfer mechanism to transfer the slide to the scanning device for scanning to obtain a scanning result.

18. The sample image scanning apparatus of claim 17, wherein, The slides include regular slides and abnormal slides, the first slide basket is used to at least load regular slides, the abnormal slides include review slides and / or emergency slides, the sample image scanning device further comprises a review device and / or an emergency device, the review device is used to feed review slides, and the emergency device is used to feed a second slide basket loaded with emergency slides; The controller is further used to: when detecting that the first transfer mechanism feeds the first slide basket, detect whether the buffer position is empty, and when the buffer position is empty, control the first transfer mechanism to transfer the regular slide from the first slide basket to the buffer position; detecting whether the buffer position is empty when the reexamining device feeds the reexamining slide, and controlling the first transfer mechanism to transfer the reexamining slide from the reexamining device to the buffer position when the buffer position is empty; detecting whether the buffer position is empty when the emergency device feeds the second slide basket loaded with emergency slides, and controlling the first transfer mechanism to transfer the emergency slides to the buffer position when the buffer position is empty; wherein the priority of the first transfer mechanism to transfer the emergency slides is higher than the priority of the first transfer mechanism to transfer the reexamining slides, and the priority of the first transfer mechanism to transfer the reexamining slides is higher than the priority of the first transfer mechanism to transfer the routine slides.

19. A sample detection system, characterized by, The sample image scanning device according to any one of claims 1-18, a first detection device, a control device, and a display device, wherein the first detection device, the sample image scanning device, and the control device are electrically connected, the first detection device is used to detect a sample and output a first detection result, the sample image scanning device is used to receive and scan a sample slide prepared by the sample image scanning device, the control device controls the sample image scanning device to receive and scan the sample slide when the first detection result is abnormal, and the display device displays the first detection result and a scanning result output by the sample image scanning device.

20. A liquid-based sample testing system, comprising: The sample image scanning device according to any one of claims 1-18, a control device, and a display device, wherein the sample image scanning device and the control device are electrically connected, the sample image scanning device is used to receive and scan a liquid-based sample slide prepared by the sample image scanning device, the control device controls the sample image scanning device to receive and scan the liquid-based sample slide, and the display device displays a scanning result output by the sample image scanning device.

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